Catalysing Innovation in Pharma IT: Keeping AstraZeneca Ahead of Disruptive Technology
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Catalyzing Innovation in Pharma IT Keeping AstraZeneca Ahead of Disruptive Technology Rob Hernandez Data Analytics lead – Tech Incubation Labs, Office of the CTO 28 September 2016
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Transcript of Catalysing Innovation in Pharma IT: Keeping AstraZeneca Ahead of Disruptive Technology
Catalyzing Innovation in Pharma ITKeeping AstraZeneca Ahead of Disruptive Technology
Rob HernandezData Analytics lead – Tech Incubation Labs, Office of the CTO 28 September 2016
The explosive pace of technological change means we all
need to be empowered to embrace new approaches
Big Data Is Reshaping Our World
Big Data & AI are changing our lives
Mapping and Navigation
Image Recognition
Language Translation
Self-repairing hardware
Natural language processing
Autonomous car
Healthcare reasoning
Home automation
Personal Assistants
Fraud Detection
Security Surveillance
Movie & Music Recommendation
Technology has already disrupted other industries
Mobile service that
enabled you to find
better ways to travel
On-demand, app-
based legal music
distribution through
streaming
Go-to-device, more
intimate, shocked the
PC industry
Displaced telecoms
companies through
free chat
Displaced retailers
and changed home
entertainment
Online rental service
to enable you to rent
and find vacation
homes
Technology giants are now coming after health
Opened their own lab to
test own drug treatments
Major tech companies
sharing better analysis toolsPivoted from photos to
printing stem cells !
Major tech companies
creating Joint Ventures
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Technology Giants Applying Big Data analytics to health
AstraZeneca
A global science-led biopharmaceutical company
Our business is providing innovative, effective medicines
that make a real difference to patients
“Science led, IT driven”
- Dave Smoley CIO, AstraZeneca
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Chief Technology Office
Competency Centres Enterprise Architecture
Uplift Govern
• Find, validate and prove the
value of 10x technologies
• Catalyse best technology
across AstraZeneca
• User Experience (UX)
• Mobility
• Develop internal expertise
with best practice, training,
guidelines, standards and
communities
• Simplify & Modernise our
technology environment
• Define future technology
roadmaps
• digital transformation and
business innovation strategy
Tech Incubation Labs
Scout
Driving Technology LeadershipCreate new value by leveraging innovative technologies across AstraZeneca and AZIT.
Technology Incubation labs
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Drive Technology
Leadership
• Accelerate innovation
culture
• Support learning between
functional silos
• Position IT as a strategic
partner
Bring Emerging
Technology In
• Reframe problems
• Leverage new
technology to improve
operations
• Exploit new business
opportunities
2 3External
Perspective
• Tech Trends
• Best practice
• Pharma and other
industries
• Potentially disruptive
developments
trends start-ups
VCs presentations
news register
showcase tools
1
scout validate
proof of concepts
Act as a technology catalyst
Tech Videos
Tech News
Tech Register
Tech Adoption
We enable communication about
technology, track internal tech and
innovation and act as expert
advisors on trends.
Recent focus areas – DATA is key
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NLP & Emotion Detection Predictive Modelling
Genomics Analysis
Big Data Analytics
Cyber Security Threat DetectionArtificial Intelligence
IoT - Sensors
Blockchain
Big Data affects all aspects of pharma
Machine Learning highlighted by
multiple AZ IT leaders as key to their
areas.
Multiple areas in the business
looking for predictive modelling
solutions but need expertise.
Volumes of Data
Next Generation Sequencing
Whole body imaging
Tissue Microarrays
Sales force optimisation
Clinical trial statistical analytics
High Throughput Screening
Toxicogenomics
Open Innovation Approaches
PowerPoint/Excel content
Structured databases
Predictive Chemistry Modelling
Unstructured data
Real-time news sentiment
experimental data capture
Wearable sensor information
Log analytics in Operations
Streaming of Data Variety of Data Complexity of Data
We’re data driven company: We need data driven decisions
Predictive modelling PoCs: 20+ use cases across AZ
Evaluated innovative Data Science
technology.
Partnered with business functions to
work through use cases.
End goal: Democratise Predictive
Modelling & ML at AZ.
Predict disease exacerbation from clinical data
Predict machine breakdown from sensor & log data
Predict clinician behaviour from Sales / interaction data
Predict drug response from RWE data
Predictive
Modelling
The PoCs served to highlight gaps
Capture DataNeed to capture the right data, manage it and make it accessible in the right way.
Working through the use cases helped us understand the steps we need to put in
place for successful projects.
Understand MLNeed to increase awareness of machine learning, what it can and can’t do and how to frame problems in the right way.
Wrangle DataEvery data challenge involves transforming, wrangling and cleaning up the data.
Partner with BusinessWork closely with the right stakeholders. Understand the decisions that will be driven by the models and the potential value of the predictions.
Big Unstructured Data – R&D Search applications
A single search platform supporting all of AZ
Scientific Partners
R&D News Alerts R&D ChemSearch
Mobile Apps
Find People at AZR&D Intelligence
Can we get it to work?Can we teach it information from the internet?Can we get it returning information about AZ?How about information from our Intranet?Can we apply it to a real use case?
“We believe Artificial Intelligence and Conversational UI will disrupt the technical landscape in AstraZeneca”
The next search front ends could be chatbots
We started off by integrating our prototype
into our Teams Slack channel
AI Chatbots
Smart
Speaker
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Automated Service desks Patient drug adherence Cognitive meeting rooms
“By 2020, 85% of customer interactions will be managed without a human” (Gartner)
Smartphone
Virtual Assistant
Messenger
Chatbot
Conversational UI
Natural Language Processing
Text Analytics
Machine Learning
Google, Amazon and Apple changing from “Mobile First” to “AI First”
Today AZ has less than 20 digital
health initiatives in flight, relatively
uncoordinated.
Digital Health – The upcoming data deluge
PROACTPatient Reported Opinions
About Clinical Trials
Turbu+ Smart Inhaler, Mobile App,
Web Portal
Flight DeckA centralised approach
for mobile app demand
management
MicroservicesA mobile-centric
microservices strategy
focused on digital
health
CTO are creating a mobile service
foundation now. A common data
layer, for data streaming, storage
and advanced analytics Supporting
R&D and Commercial.
Developed video extraction Text
AZ CHATBOT
PROACT
Developed a mobile app to capture patient videos and diaries to understand drug tolerability and
potential side effects in phase 1 clinical trials.
Developed facial expression Sentiment
Internet of Things & The Physical Web
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Industrial Sensors
Smart Buttons
Beacons
Shipment Tracking
All brought together on one cloud platform
Wearables
“By 2020, there will be 21 Billion connected devices” - Gartner
And we are all finding our own direction
Astra
Zeneca
Genomics Initiative,
2M sequenced to
transform drug
discovery.
Start-ups
Contact
Acknowledgements
Nick Brown, Adrian Wong, Josh Mesout,
Hariprasad Radhakrishnan, Steve Woodward
and many other AZ colleagues
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UK Tech Lab Director
Scouting for disruptive 10X technologies
We can be your conduit into AstraZeneca
Venture Capital Institutes Innovative Companies
Mobile Digital Health Creative Tech Big Data IoT DevOps
