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Name of Drug Action Mechanism of

Action

Adverse effects Indication Contraindication Nursing

Management

Omeprazole Proton pumpinhibitor

Chemical effect:Inhibits acid

(proton) pumps

binds to

hydrogen-

potassium

adenosine

triphosphate on

secretory surfaceof gastric acid.

Therapeutic

effect:

Relieves

symptoms caused

by excessive

gastric acid.

Constipation,diarrhea,

flatulence,

nausea, vomiting,

& acid

regurgitation,

abdominal pain,

asthma,

headache,dizziness,rash.

Contraindicated inpatients

hypersensitive to

the drug or any of

its components.

In children ages 2

to 16 years, drug

may be used to

treat GERD,erosive

esophagitis, and

for maintenance

of heading erosive

esophagitis

(tablets and

capsules only).

Explain to thepatient how to

reconstitute

powder for oral

suspensions.

Empty pocket

contents into a

small cup

containing 2 tbs ofh2O. Stir well and

drink moderately.

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Drug Name Action Mechanism ofAction

Adverse effect Indication Contraindication NursingManagement

Ranitidine Anti-ulcerative Chemical effect:

Competitively

inhibits action of

H2 at receptor

sites of parietal

cells, decreasing

gastric acidsecretion.

Therapeutic

effect:

Relieves GI

discomfort.

Diarrhea, con

tipation, dizziness,

tiredness,

headache, rash.

Rarely allergic

reactions,

arthralgia, blooddisorders,

hepatoxicity &

pancreatitis.

Contraindicated in

patients

hypersensitive to

drug or any of its

components.

Dont use

aluminum based

needles or

equipment when

mixing or giving

drug parenterally

because drug isincompatible with

aluminum.

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Name of Drug Action Mechanism ofAction

Adverse Effect Indication Contraindication NursingManagement

Fluimucil Zambon Liver detoxifies Chemical effect:

Increases

respiratory tract

fluids to help

liquefy tenacious

secretions.

Restoresglutathione in

liver to treat

acetaminophine

toxicity.

Rarely, uticaria,

bronchospasm,

nausea, vomiting.

Acute & chronic

respiratory tract

affections with

abundant mucus

secretions.

Contraindicated in

patients

hypersensitive to

drug use

cautiously in

debilated patients

with reverserespiratory

insufficiency. In

patients with

asthma or a

history of

bronchospasm.

Instruct patient to

follow directions

on drug label

exactly. Explain

importance of

using drug as

directed.

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Drug Name Action Mechanism of

Action

Adverse Effect Indication Contraindication Nursing

Management

Sertraline Nausea, diarrhea,loss stool,

anorexia, dry

mouth, increased

sweating, rarely

pancreatitis, &

serious liver

events.

Treatment ofsymptoms of

depressions, panic

post traumatic

stress disorder,

obsessive,

compulsive

disorder.

Advice patient tomix the oral with

4 oz of H2O,

gingerale or

lemon-lime soda

only, and to take

the dose right

away.

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