Case Study-Xylitol. Result Book Nelson Textbook of Pediatrics, 2007 18e. –possible sources of...
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Case Study-Xylitol
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Result
Book• Nelson Textbook of Pediatrics, 2007 18e.
– possible sources of evidences 2004-2006
Review• Dental caries. Lancet 369:51-9 2007• Infect Dis Clin North Am 2007; 21(2): 471-502
– possible sources of evidences 2006-2007
Patient Education• Early childhood caries,• Dental cavities, Radiography, Dental
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Rampant caries (early childhood caries) in 3 yr old child
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Basic Dental Anatomy
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Diagnosis (iceberg metaphor)
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Caries Process
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Clinical Presentations
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Clinical Implications
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Clinical Implications
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Patient Education
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Case - Clinician
• 張小妹,六歲,喜歡吃糖但卻滿口蛀口。
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Ask• P: children/adults (with dental caries)• I: chewing gum with xylitol• C: chewing gum without xylitol• O: incidence of dental decay
• Type of Question: therapy• Keyword:
– Dental caries– xylitol
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Acquire / Search2007
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Search - xylitol dental caries2009
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Acquire / Search
2009
xylitol dental caries
xylitol
2007
2009
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Advanced Search - Article Type
• Cochrane — thoes found in The Cochrane Database of Systematic Reviews (CDSR)
• Trials — Narrows you search to articles containing information about Clinical Trials, Randomized Control Trials, and similar articles.
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2005
2005
2004
2007
2008
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等級 治療 診斷 預後 病因
I 第 II 級證據的系統回顧 (systematic review)
II隨機對照
試驗由連續或隨機取樣組成的橫斷面研究
前瞻性起始世代研究
前瞻性世代研究
LOE: Level of Evidence (Oxford)
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LOE (GRADE)
• 評分方式:結合研究方法,研究品質,一致性,相關性• 高( high ) = further research is very unlikely to change
our confidence in the estimate of effect • 中(moderate ) = further research is likely to have an
important impact on our confidence in the estimate of effect and may change the estimate
• 低( low ) = further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate
• 極低( very low ) = any estimate of effect is very uncertain
The GRADE Working Group - http://www.gradeworkinggroup.org/
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