CASCADED LINEAR-SYSTEMS ANALYSIS OF CMOS FLAT-PANEL DETECTORS FOR DIGITAL...

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Biomedical Mechatronics Lab CASCADED LINEAR-SYSTEMS ANALYSIS OF CMOS FLAT-P ANEL DETECTORS FOR DIGITAL RADIOGRAPHY Seung Man Yun, Min Kook Cho, Chang Hwy Lim, Ho Kyung Kim * School of Mechanical Engineering, Pusan National University, Republic of Korea Thorsten Graeve Rad-icon Imaging Corp., Belick street, Santa Clara, CA 95045-2404 USA Hyosung Cho Department of Radiological Science, Yonsei University, Republic of Korea Jung-Min Kim College of Health Science, Korea University, Republic of Korea ANDE 2007

Transcript of CASCADED LINEAR-SYSTEMS ANALYSIS OF CMOS FLAT-PANEL DETECTORS FOR DIGITAL...

Page 1: CASCADED LINEAR-SYSTEMS ANALYSIS OF CMOS FLAT-PANEL DETECTORS FOR DIGITAL RADIOGRAPHYbml.pusan.ac.kr/Publication/PDF/IntCon/036_IntConf_an… ·  · 2008-11-04Biomedical Mechatronics

Biomedical Mechatronics Lab

CASCADED LINEAR-SYSTEMS ANALYSIS

OF CMOS FLAT-PANEL DETECTORS

FOR DIGITAL RADIOGRAPHY

Seung Man Yun, Min Kook Cho,Chang Hwy Lim, Ho Kyung Kim*

School of Mechanical Engineering, Pusan National University, Republic of Korea

Thorsten GraeveRad-icon Imaging Corp., Belick street, Santa Clara, CA 95045-2404 USA

Hyosung ChoDepartment of Radiological Science, Yonsei University, Republic of Korea

Jung-Min KimCollege of Health Science, Korea University, Republic of Korea

ANDE 2007

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Motivation

• For better design and usage of various radiographic modalities▫ Computed tomography (CT), digital radiography (DR)

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Miniatured cone-beam CT system using CMOS flat-panel detector

SO 11-III [2007-494] October 19, 17:00

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

CMOS flat panel detector

• Photodiode arrays manufactured by CMOS process with scintillator▫ Smaller image lag and larger fill factor than a conventional amorphous

photodiode array

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Rad-icon RadEye1TM

Array format512 1024

pixels/1 detector

Pixel pitch 48 m

Field of view25 50

mm2/1 detector

Dynamic range 85 dB (>14 bits)

ADC bit-depth 12 bits

Pixel fill factor 0.87

Kodak Lanex Min-RTM

Composition Gd2O2S:Tb

Coverage 33.91 mg/cm2

Thickness 90 m

Density 3.77 g/cm3

RadEyeTM

Min-RTM

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

X-ray imaging system evaluation

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DQE

NPS

Resolution

Contrast

Noise

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Objectives

• Analyzing DQE of CMOS flat-panel detector for digital radiography▫ As a function of design parameters using cascaded model analysis

• Cascaded linear-systems theory-based modeling and simulation▫ Numerical modeling of NPS and DQE for x-ray imaging system evaluation

• Investigating a validity of the proposed cascaded model▫ Comparison with experimentally measured data for same condition

• Simulating DQE of the CMOS photodiode array with various design parameters▫ Photodiode quantum efficiency, fill factor, additive electronic noise

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Evaluation procedure

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)(NNPS

)(MTF)(DQE

0

2

fq

ff

2D FFT

1D FFT

• Slit images• Gain-offset corrections

• Synthesizing LSF`s

• HVL measurements• Spectral simulation• Tuning kVp• Estimating fluence

• Scaling for non-uniformity• Averaging• Extracting 1D profiles

• White images• Gain-offset corrections• Detrending• Conversion into relative noise• Windowing

f

f

f

mmAl

I/I 0

spect

ral density

MTF

1

DQ

E

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Cascaded linear system analysis

• Cascade model describes the interacting of each process in detectors▫ The response of an system be linear and shift invariant (LSI), random noise

process be wide-sense stationary

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Stage Description Symbol Process

Incident X-ray q Uniform distribution

Quantum detection g1=AQBinomial selection

Quantum amplification g2=AMBinomial selection

Quantum scattering TscnStochastic blurring

Quantum conversion g4=ADBinomial selection

Aperture integration TapertDeterministic blurring

Sampling III Deterministic process

Additive noise saddDeterministic process

1g

2g

scnT 3

gapert

T III addσ signaldigital q

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

• DQE of cascaded linear-systems of the CMOS flat-panel detectors

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Fluence System gain

Noise power spectrum Additive electronic noise

System MTF

22

0

224

2222

σ)()(11

)()( )( )(DQE

addk

apertscn

M

DDMQ

apertscnDMQ

dd

kT

d

kT

I

AAAAAaq

TTAAAaq

ρρ

ρρρ

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Monte Carlo simulation

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Absorption Reflection

Refraction & transmission

Energy deposition& light conversionScintillator

Air gap = 1 m

Light photon detection plane

Spectral source sampling

MCNPXTM

DETECT2000TM

Polished surface

Grounded surface

Refractive index of phosphor = 2.6Absorption mfp. = 10 cmScattering mfp = 0.0017 cm

Pencil beam

Thin slap geometry: radius >> thickness

Subdividing the scintillatorinto thin sublayers to calculate the partial energy deposition and to estimate the escape probability of light photons with respect to the depth!!! Source

AED

OPD

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Experimental setup

• RQA 5 experimental condition (IEC 62220-1)

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Tube voltage 70 kVp (RQA5)

Tube current 0 ~ 125 mA

Exposure time at 1fps 550 ms

Source-to-detector distance 1000 mm

Added filter 21 mmAl

Added filter

Source-to-detector distance

X-raytube

CM

OS d

ete

ctor

surface

10 m wide slit camera(I.I.E. GmbH, Aachen, GER)

Slit camera

Ion chamber

Ion chamber(RAD-CHECK PLUS 06-526)

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Cascaded model simulation parameter

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Description Parameters

Pixel pitch d = 48 m

Pixel fill factor g = 87 %

pixel aperture a = 44.72 m

Incidence of X-ray q = 4.4×105 mm-2

Quantum absorption efficiency of screen AQ = 0.23

Average conversion efficiency of screen AM = 520

Quantum efficiency of photodiode AD = 0.55

Statistical swank factor I = 0.9

MTF of the scintillator Tscn( f ) = (1+1.0001f 2)-1

MTF due to the aperture integration Tapert( f ) = |sinc(af )|

Additive electronic noise sadd = 1100 e-

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Model validation

• Compared with Kodak Lanex Min-RTM screen (RQA 5, @50mA)

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Effect of a photodiode quantum efficiency

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Effect of a fill factor

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Effect of a additive electronic noise

• The DQE is vulnerable to the additive noise than the other parameters

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Cascaded Linear-systems Analysis of CMOS flat-panel detectors for digital radiography, ANDE 2007

Conclusion

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• Cascaded linear-systems analysis of CMOS detector▫ Describes the signal and noise propagation

▫ Estimates its overall imaging performance

▫ Additive electronic noise is the most significant design parameter

• The developed model is a useful tool to design the CMOS flat-panel detector for digital radiography

• Based on this study, we can simulate a optimized design parameters of the CMOS photodiode array with scintillator