Cancer Clinical Trials A treatment option for cancer patients.
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Transcript of Cancer Clinical Trials A treatment option for cancer patients.
Cancer Clinical TrialsA treatment option for cancer patients
Today’s standard treatment options are a product of prior research
Clinical Trials serve as vehicles of innovation and progress resulting in: Improved clinical outcomes Personalized treatment plans which
are more effective and less toxic
Barriers based in common misconceptions
Fear of abuse or exploitation:
My patients will be treated like
“guinea pigs”
if they participate in a clinical trial
*Slide content adapted from the Education Network to Advance Cancer Clinical Trials (ENACCT), used with permission.
Barriers based in common misconceptions
Misunderstanding of the purpose of cancer clinical trials:
“Clinical trials are only for patients who have run out of other
treatment options”
*Slide content adapted from the Education Network to Advance Cancer Clinical Trials (ENACCT), used with permission.
Barriers based in common misconceptions
Misunderstanding of design/ethics of cancer clinical trials:
“My patients may receive a placebo instead of appropriate
treatments”
*Slide content adapted from the Education Network to Advance Cancer Clinical Trials (ENACCT), used with permission.
Clinical Trials provide a good quality option for care
Expert panels state that clinical trials provide a high quality treatment option for cancer patients at all stages of the disease continuum
National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology:
“…the best management of any cancer patient is in a clinical trial.”
Institute of Medicine: “…therapies offered through Cancer Clinical Trials should ideally be considered the preferred treatment choice for physicians and patients, if they are available.”
*Slide content from the Education Network to Advance Cancer Clinical Trials (ENACCT), used with permission.
Phase IIIStudy Question:
Is the agent better than the standard approach?
n = 100s-1000s
Phase IIStudy Question:
Is the agent effective?n = <100
Phase IStudy Question:
Is the agent safe?n = 15–20
Phases of Cancer Clinical Trials:
*Slide content adapted from the Education Network to Advance Cancer Clinical Trials (ENACCT),
used with permission.
A call to actionProgress is a result of a communal effort that requires a solid partnership between patients and doctors. Each individual physician can participate by:Referring patients to oncologists that
conduct clinical trials. Introducing the concept of a clinical trial as
a viable treatment option.Providing patients with print information
about clinical trials.Encouraging patients to ask their oncologist
about clinical trials
We are available to answer your questions:
[Insert contact information]
Reference Education Network to Advance Cancer Clinical Trials (ENACCT):
http://www.enacct.org Comis RL, Miller JD, et al. Public attitudes toward participation in
cancer clinical trials. J Clin Oncol. 2003;21(5):830-835. National Comprehensive Cancer Network Guidelines:
http://www.nccn.org/professionals/physician_gls/f_guidelines.asp
National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Institute of Medicine of the National Academies; 2010.
Fenton L, Rigney M, Herbst R. Clinical trial awareness, attitudes, and participation among patients with cancer and oncologists. Commun Oncol. 2009;6:207-213.
Comis RL, Miller JD. Cancer clinical trials awareness and attitudes in cancer survivors. Philadelphia (PA): Coalition of Cancer Cooperative Groups; 2005: http://www.cancertrialshelp.org/Icare_content/icMainContent.aspx?intAppMode=19.