Valenzuela Et Al_2013_Exploring the Subjective Experience of the Rubber Hand Illusion
Can Hand Disownership in the Rubber Hand Illusion Reduce Pain?
-
Upload
simonvanrysewyk -
Category
Health & Medicine
-
view
139 -
download
0
Transcript of Can Hand Disownership in the Rubber Hand Illusion Reduce Pain?
Can Hand Disownership in the Rubber Hand Illusion Reduce Pain?
Simon van RysewykPost-Doctoral Fellow
Graduate Institute of Medical Humanities Taipei Medical University
Pain
‘An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.’ (IASP)
What does this pain definition imply?
Are there other important features of pain?
2RHI Pain
Pain
The multiple components of pain can separate:
• Nociception is not pain
– phantom pain, allodynia, SIA
• Pain sensation is not always painful
– frontal lobotomy, opiate analgesics
The link between pain components is not always strong.
RHI Pain 3
Types of Nociceptive Pain: Superficial
Fast (‘first pain’)
• sharp, pricking
• acute
• skin, muscles, peripheral nerves
• Aδ III fibers
• neospinothalamic
4RHI Pain
Types of Nociceptive Pain: Superficial
Burning
• burning, sore
• acute, chronic
• skin, muscles
• C IV fibers
• archispinothalamic,paleospinothalamic
RHI Pain 5
Types of Nociceptive Pain: Deep
Slow (‘second pain’)
• dull, aching
• chronic
• viscera, joints, tendons
• C IV fibers
• paleospinothalamic
6RHI Pain
RHI Pain 7
Nociceptive Pain and the RHI
RHI Pain 8
Can pain be felt in a rubber hand?
Capelari et al. (2009)
Aim: To study the interaction between vision, touch, proprioception, and pain.
Hypothesis: Nociceptive pain will inhibit the RHI because illusory localization of noxious stimuli may lead to actual tissue damage.
RHI Pain 9
Capelari et al. 2009
Conditions: synchronous, asynchronous (tactile ± nociceptive)
Materials: paint brush, sharp pin
Measures: VAS (0-10 cm, RHI magnitude), Drift, 2 questionnaires (Botvinick & Cohen (1998)
RHI Pain 10
Capelari et al. 2009
Procedure:
4 min. stroking right index fingers both hands
randomized conditions
questionnaires were completed after the experiment.
RHI Pain 11
Capelari et al. 2009
Main Results:
80% tactile RHI
77% tactile-nociceptive RHI
Subject RHI sensation mostly in response to visible stimuli.
RHI Pain 12
Mean VAS and SE per stimulus mode
RHI Pain 13
Mean VAS and SE for drift per condition
RHI Pain 14
*p ˂ 0.001
Capelari et al. (2009)
Implications for Pain:
Standard RHI does not inhibit nociceptive pain.
RHI can alter pain-location.
Pain localization involves similar mechanisms to those for innocuous touch.
RHI Pain 15
Pain Reduction and RHI: Hypothesis
RHI disrupts thermoregulation: ↓ in skin temperature (Moseley et al. 2008)
RHI disrupts immunoregulation: ↑ reactivity to intradermal histamine (Barnsley et al. 2012)
Hypothesis: Since tissue damage threatens homeostasis, RHI may reduce pain.
RHI Pain 16
Mohan et al. 2013
Aim: To study if RHI can reduce pain.
Hypothesis: RHI will have an analgesic effect on pain evoked by noxious stimuli given on the real right hand.
RHI Pain 17
Mohan et al. 2013
Conditions: synchronous, asynchronous (tactile ± noxious or innocuous temperature)
Materials: paint brush, heat probe
Measures: VAS (0-10 cm), de-briefing questionnaire (Botvinick & Cohen, 1998)
RHI Pain 18
Mohan et al. 2013
Procedure:
RHI Pain 19
Mohan et al. 2013
Main Results:
RHI Pain 20
Mean & SE for questionnaire
RHI Pain 21
Mean & SE for pain ratings
RHI Pain 22
Mohan et al. 2013
Implications for Pain:
Standard RHI does not reduce nociceptive pain.
Pain components can be independently manipulated.
Pain localization involves similar mechanisms to those for innocuous touch.
RHI Pain 23
Can Left-Hand RHI Reduce Pain?
RHI Pain 24