Caffeine piece in Wired

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    2737 BC

    Chinese emperor Shen

    Nung is said to dis-

    cover tea when leaves

    blow into his cup o

    hot water.

    ca. 1000

    Cofee, previously

    eaten as beans, is irst

    inused with water.

    AD 350

    The irst account o

    planting and drink-

    ing tea is published in

    China.

    1300s

    The process o

    roasting cofee is

    discovered.

    1511

    Meccas governor

    bans cofee, citing

    ill health efects

    and bad behavior in

    those who drink it.

    Th HistorHighlights oour 5,000-year addictionto cafeine.

    THePRODUCTS

    Hr ar just aractio o th quick

    ixs o thmarkt toda.

    Isid th ovrstimulatd, udrrgulatd, multiatioal idustr.caf

    feine

    caffein

    e

    35

    208

    160

    149

    200

    54

    47

    60

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    caffe i ne has go ne c r az y . It now comes in so many orms that its hard to keep up: sot drinks,

    obviously, but also energy drinks, energy shots, chewing gum, sports gels, and nasal sprays. In all o

    them, the marquee ingredient is a white powder, delivered to our bloodstreams by a sophisticated

    global supply chain that ew o us know anything about. The scale o this industry is as eye-

    opening as a NoDoz. Americans plow through more than 15 million pounds o powdered caeine

    annuallyenough to ill a reight train 2 miles long, all 270 cars loaded to the brim. This

    turbocharging might be taking a toll on our health. US emergency room visits related to energy

    drinks spiked rom 1,100 in 2005 to 13,000 in 2009, and in November the FDA announced it was

    investigating 5-Hour Energy ater 13 deaths were associated with the popular product. Through it

    all, sales continue to jitter upward. We have become creatures that turn caeine into motion, and

    the corner store is our illing station. Heres a graphical look at the drug that keeps America moving.

    1734

    J. S. Bach composes

    the Cofee Cantata.

    1886

    Coca-Cola is

    introduced.

    1615

    Venetian merchants

    introduce cofee to

    Europe.

    1819

    Friedlieb Ferdinand

    Runge, a German

    chemist, isolates ca-

    eine rom cofee.

    1895

    Emil Fischer, another

    German chemist,

    synthesizes cafeine

    rom urea.

    1898

    Pepsi-Cola is

    introduced.

    By MURRAy CARPenTeR ILLUSTRATIOnS By CARL DeTORReS

    224

    50

    5069

    80

    100

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    320

    WIReD 077FEB 2013

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    Sthtic CafiThese days, the majority o cafeine is made in

    chemical actoriesand most o that happens in

    China. According to Panjiva, which tracks global

    trade, just three Chinese irms manuacture nearly

    hal o the cafeine consumed in the US. Diferent

    actories make cafeine in slightly diferent ways,

    but heres how German irm BASF does it.

    1909

    Federal government

    seizes shipment o

    Coca-Cola over the

    alleged ill efects o

    cafeine.

    1911

    Coke hires psy-

    chologist Harry

    Hollingworth, who

    demonstrates the

    beneits o cafeine.

    1938

    Nesca instant cofee

    is launched.

    1980

    Journalists at the

    1980 Democratic

    National Convention

    are ofered emergency

    NoDoz kits.

    1985

    Jolt Cola is introduced.

    1992

    Starbucks goes public.

    THePOWDeRThr ar two was

    to produc powdrdcafi: Ri it or

    mak it rom scratch.

    natural CafiAmericas largest natural caeine producer is

    Maximus Cofee Group, which extracts it rom

    more than 100 million pounds o beans per year.

    Heres how.

    Urea

    MeThyLaMine

    forMic aciD

    TheoPhyLLine

    caffeine

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    THe PROBLeM

    Cafi is addictiv; also, sic

    its a diurtic, it ca caus dhdra

    tio. But worst o all, i rar cass

    a ovrdos o cafi ca kill ou,

    tpicall b stoppig our hart.

    Th FDA hast rlasd much data

    about th 13 daths its ivstigat

    ig, but i at last thr cass th

    oficial caus o dath was hart

    attack. Usuall it taks a lot o ca

    i to gt thr. I April 2010,a Brito amd Michal Bdord

    at two spoouls o pur cafi

    powdr ad washd it dow with a

    rg drik. H quickl vomitd,

    collapsd, ad did. But Bdord

    likl cosumd mor tha 5 grams

    o cafith quivalt o

    24 shots o 5Hour erg. Thats

    mor tha v th biggst buzz

    chasr would vr wat to swallow.

    THePOWeR-UP

    Cafi starts bcrossig th bloodbraibarrirth it crats

    fcts throughoutth bod.

    1997

    Red Bull is launched

    in the US.

    2003

    Stay Alert gum is

    introduced.

    2004

    5-Hour Energy creates

    the irst energy shot.

    2009

    Scientists and state

    attorneys general

    petition the FDA to

    restrict alcoholic

    energy drinks.

    2012

    The FDA investigates

    claims o 13 deaths

    related to 5-Hour

    Energy; results are

    still pending.

    2011

    LeBron James

    introduces Sheets,

    melt-on-the-tongue

    cafeine strips.

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