C Number: ALL€¦ · TDMS No. 20310 - 01 P09: NON-NEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL Date...

TDMS No. 20310 - 01 P09: NON-NEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL Date Report Requested: 07/22/2009

Test Type: 26-39 WEEKS 3'-Azido-3'-deoxythymidine (AIDS) Time Report Requested: 11:48:12

Route: GAVAGE CAS Number: 30516-87-1 First Dose M/F: NA / 11/18/04

Species/Strain: MICE/C3B6F1-+/Trp53(tm1Brd) Lab: NCTR

C Number: C20310C

Lock Date: 12/01/2008

Cage Range: ALL

Date Range: ALL

Reasons For Removal: ALL

Removal Date Range: ALL

Treatment Groups: Include 912 Vehicle 9 mo F Include 913 AZT 40 9 mo F Include 914 AZT 80 9 mo F

Include 915 AZT 120 9 mo F

Study Gender: Female

TDMSE Version: 2.1.0

ALIMENTARY SYSTEM.........................................................................................................................................................................................................

Esophagus + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Gallbladder + + + + + + + + + + + + + + + + + A + + + + + + +.........................................................................................................................................................................................................

Intestine Large, Cecum + + + + + + + + + + + + + + + + + A + + + + + + +Hyperplasia, Lymphoid 2 3

.........................................................................................................................................................................................................

Intestine Large, Colon + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Intestine Large, Rectum + + + + + + + + + + + + + + + + + A + + + + + + +.........................................................................................................................................................................................................

Intestine Small, Duodenum + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Intestine Small, Ileum + + + + + + + + + + + + + + + + + A + + + + + + +.........................................................................................................................................................................................................

Intestine Small, Jejunum + + + + + + + + + + + + + + + + + A + + + + + + +.........................................................................................................................................................................................................

Liver + + + + + + + + + + + + + + + + + + + + + + + + +Tension Lipidosis 1 1 1Vacuolization Cytoplasmic 1 1 1 1 1 2

.........................................................................................................................................................................................................

Mesentery +Hemorrhage 3

.........................................................................................................................................................................................................





DAY ON TEST0198

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C3B6F1-+/TRP53(TM1BRD) NCTRMICE FEMALE

ANIMAL IDVehicle 9 mo F

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females(cont...)

* .. Total animals with tissue examined microscopically; Total animals with lesion and mean severity grade+ .. Tissue examined microscopically M .. Missing tissue 1-4 .. Lesion qualified as:x .. Lesion present A .. Autolysis precludes evaluation 1) Minimal 3) ModerateI .. Insufficient tissue BLANK .. Not examined microscopically 2) Mild 4) Marked

Pancreas + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Salivary Glands + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1 2 1 1 1 2 1 1 1 1 1 1 1 1

.........................................................................................................................................................................................................

Stomach, Forestomach + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Stomach, Glandular + + + + + + + + + + + + + + + + + A + + + + + + +

CARDIOVASCULAR SYSTEM.........................................................................................................................................................................................................

Blood Vessel + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Heart + + + + + + + + + + + + + + + + + + + + + + + + +Inflammation, Chronic Active 1

ENDOCRINE SYSTEM.........................................................................................................................................................................................................

Adrenal Cortex + + + + + + + + + + + + + + + + + + + + + + + + +Subcapsular, Hyperplasia 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

.........................................................................................................................................................................................................

Adrenal Medulla + + + + + + + + + + + + + M + + + + + + + + + + +.........................................................................................................................................................................................................

Islets, Pancreatic + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Parathyroid Gland + + + + M M + + + M + + + + + M + + + + + + M + +





DAY ON TEST0198

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females(cont...)


.........................................................................................................................................................................................................

Pituitary Gland + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Thyroid Gland + + + + + + + + + + + + + + + M + + + + + + + + +Degeneration 1

GENERAL BODY SYSTEMNONE

GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + + M + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Ovary + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Uterus + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Polymorphonuclear 2Endometrium, Hyperplasia, Cystic 1 2 1Lumen, Dilatation 1 1 1 2 2 1 1 1 1

.........................................................................................................................................................................................................

Vagina M + + + + + + + + + + + + + + + + + + + + + + + +

HEMATOPOIETIC SYSTEM.........................................................................................................................................................................................................

Bone Marrow + + + + + + + + + + + + + + + + + + + + + + + + +





DAY ON TEST0198

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females(cont...)


.........................................................................................................................................................................................................

Lymph Node +Lumbar, Hyperplasia, Lymphoid 2

.........................................................................................................................................................................................................

Lymph Node, Mandibular + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Lymph Node, Mesenteric + + + + + + + + + + + + + + + + + + + + + + + + +Hyperplasia, Lymphoid 1 2 2 2 1 1 1 1

.........................................................................................................................................................................................................

Spleen + + + + + + + + + + + + + + + + + + + + + + + + +Hematopoietic Cell Proliferation 3 2 4 3 2Hyperplasia, Lymphoid 2 2 2 2

.........................................................................................................................................................................................................

Thymus + + M + + + + + + + + + + + + + + A + + + + + + +Hyperplasia, Lymphoid 2 2

INTEGUMENTARY SYSTEM.........................................................................................................................................................................................................

Mammary Gland + + M + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Skin + + + + + + + + + + + + + + + + + + + + + + + + +

MUSCULOSKELETAL SYSTEM.........................................................................................................................................................................................................

Bone, Femur + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................





DAY ON TEST0198

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females(cont...)


Skeletal Muscle + + + + + + + + + + + + + + + + + + + + + + + + +Atrophy 2 2Cyst 4

NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Brain, Cerebellum + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Brain, Cerebrum + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Peripheral Nerve + +Axon, Degeneration 2 3

.........................................................................................................................................................................................................

Spinal Cord +Axon, Degeneration 2

RESPIRATORY SYSTEM.........................................................................................................................................................................................................

Lung + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Nose + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Trachea + + + + + + + + + + + + + + + + + + + + + + + + +





DAY ON TEST0198

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females(cont...)


SPECIAL SENSES SYSTEM.........................................................................................................................................................................................................

Eye + + + + + + + + + + + + + + + + + A + + + + + + +Cataract 1

.........................................................................................................................................................................................................

Harderian Gland + + + + + + + + + + + + + + + + + + + + + + + + +

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + + + + + + + + + + + + + + + + + + + + + + + + +Casts Protein 1Cyst 1Infiltration Cellular, Lymphocyte 1 1 2 1 1 1 1 1Mineralization 1

.........................................................................................................................................................................................................

Urinary Bladder + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1





DAY ON TEST0198

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females(cont...)



Esophagus + 26.........................................................................................................................................................................................................

Gallbladder + 25.........................................................................................................................................................................................................

Intestine Large, Cecum + 25Hyperplasia, Lymphoid 2 2.5

.........................................................................................................................................................................................................

Intestine Large, Colon + 26.........................................................................................................................................................................................................

Intestine Large, Rectum + 25.........................................................................................................................................................................................................

Intestine Small, Duodenum + 26.........................................................................................................................................................................................................

Intestine Small, Ileum + 25.........................................................................................................................................................................................................

Intestine Small, Jejunum + 25.........................................................................................................................................................................................................

Liver + 26Tension Lipidosis 3 1.0Vacuolization Cytoplasmic 6 1.2

.........................................................................................................................................................................................................

Mesentery 1Hemorrhage 1 3.0

.........................................................................................................................................................................................................





DAY ON TEST0336

.................................................................................................................................................................



00632 * TOTALS


Pancreas + 26.........................................................................................................................................................................................................

Salivary Glands + 26Infiltration Cellular, Lymphocyte 2 15 1.2

.........................................................................................................................................................................................................

Stomach, Forestomach + 26.........................................................................................................................................................................................................

Stomach, Glandular + 25


Blood Vessel + 26.........................................................................................................................................................................................................

Heart + 26Inflammation, Chronic Active 1 1.0


Adrenal Cortex + 26Subcapsular, Hyperplasia 25 1.0

.........................................................................................................................................................................................................

Adrenal Medulla + 25.........................................................................................................................................................................................................

Islets, Pancreatic + 26.........................................................................................................................................................................................................

Parathyroid Gland + 21





DAY ON TEST0336

.................................................................................................................................................................



00632 * TOTALS


.........................................................................................................................................................................................................

Pituitary Gland + 26.........................................................................................................................................................................................................

Thyroid Gland + 25Degeneration 1 1.0


GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + 25.........................................................................................................................................................................................................

Ovary + 26.........................................................................................................................................................................................................

Uterus + 26Infiltration Cellular, Polymorphonuclear 1 2.0Endometrium, Hyperplasia, Cystic 3 1.3Lumen, Dilatation 1 10 1.2

.........................................................................................................................................................................................................

Vagina + 25


Bone Marrow + 26





DAY ON TEST0336

.................................................................................................................................................................



00632 * TOTALS


.........................................................................................................................................................................................................

Lymph Node 1Lumbar, Hyperplasia, Lymphoid 1 2.0

.........................................................................................................................................................................................................

Lymph Node, Mandibular + 26.........................................................................................................................................................................................................

Lymph Node, Mesenteric + 26Hyperplasia, Lymphoid 8 1.4

.........................................................................................................................................................................................................

Spleen + 26Hematopoietic Cell Proliferation 5 2.8Hyperplasia, Lymphoid 4 2.0

.........................................................................................................................................................................................................

Thymus + 24Hyperplasia, Lymphoid 2 3 2.0


Mammary Gland + 25.........................................................................................................................................................................................................

Skin + 26


Bone, Femur + 26.........................................................................................................................................................................................................





DAY ON TEST0336

.................................................................................................................................................................



00632 * TOTALS


Skeletal Muscle + 26Atrophy 2 2.0Cyst 1 4.0

NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + 26.........................................................................................................................................................................................................

Brain, Cerebellum + 26.........................................................................................................................................................................................................

Brain, Cerebrum + 26.........................................................................................................................................................................................................

Peripheral Nerve 2Axon, Degeneration 2 2.5

.........................................................................................................................................................................................................

Spinal Cord 1Axon, Degeneration 1 2.0


Lung + 26.........................................................................................................................................................................................................

Nose + 26.........................................................................................................................................................................................................

Trachea + 26





DAY ON TEST0336

.................................................................................................................................................................



00632 * TOTALS



Eye + 25Cataract 1 1.0

.........................................................................................................................................................................................................

Harderian Gland + 26

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + 26Casts Protein 1 1.0Cyst 1 1.0Infiltration Cellular, Lymphocyte 1 9 1.1Mineralization 1 1.0

.........................................................................................................................................................................................................

Urinary Bladder + 26Infiltration Cellular, Lymphocyte 1 1.0





DAY ON TEST0336

.................................................................................................................................................................



00632 * TOTALS



Esophagus + + + + + + + + + + + + + + + + + + + + + + + + +Adventitia, Necrosis 2

.........................................................................................................................................................................................................

Gallbladder + + + + + + + + + + + + + + + A + + + + + + + + +.........................................................................................................................................................................................................

Intestine Large, Cecum + + + + + + + + + + + + + + + + + + + + + + + + +Hyperplasia, Lymphoid 2 2

.........................................................................................................................................................................................................

Intestine Large, Colon + + + + + + + + + + + + + + + A + + + + + + + + +.........................................................................................................................................................................................................

Intestine Large, Rectum + + + + + + + + + + + + + + + + + + + + + + + + +Hyperplasia, Lymphoid 2

.........................................................................................................................................................................................................

Intestine Small, Duodenum + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Intestine Small, Ileum + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Intestine Small, Jejunum + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Liver + + + + + + + + + + + + + + + + + + + + + + + + +Inflammation, Chronic Active 1 1Tension Lipidosis 1 2 1 2Vacuolization Cytoplasmic 1 1 1 1

.........................................................................................................................................................................................................





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ANIMAL IDAZT 40 9 mo F

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females(cont...)


Pancreas + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Salivary Glands + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1 1 1 1 1 2 1 1 1 1 1 1 1

.........................................................................................................................................................................................................


Stomach, Glandular + + + + + + + + + + + + + + + + + + + + + + + + +


Blood Vessel + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Heart + + + + + + + + + + + + + + + + + + + + + + + + +Bacterium XPericardium, Necrosis 2


Adrenal Cortex + + + + + + + + + + + + + + + + + + + + + + + + +Subcapsular, Hyperplasia 1 1 1 1 1 1 1 1 1 2 2 2 2 1 1 1 2 1 1 1 1 1 1

.........................................................................................................................................................................................................

Adrenal Medulla + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................






DAY ON TEST0334

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females(cont...)


Parathyroid Gland + + + + + + + + M M M + + + + M M + + + + + + + +Cyst 1

.........................................................................................................................................................................................................

Pituitary Gland + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Thyroid Gland + + + + + + + + + + + + + + + + + + + + + + + + +Cyst 1Degeneration 1 1Ectopic Thymus X X

GENERAL BODY SYSTEM.........................................................................................................................................................................................................

Tissue NOS +

GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + + + + + + + + + + + + + M + + + + + + + + + + +.........................................................................................................................................................................................................

Ovary + + + + + + + + + + + + + + + + + + + + + + + + +Cyst

.........................................................................................................................................................................................................

Uterus + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Polymorphonuclear 2 2 3Endometrium, Hyperplasia, Cystic 2 2 2 2Lumen, Dilatation 2 1 2 1 1 1 1 1 1 2 2

.........................................................................................................................................................................................................

Vagina + + + + + + + + + + + + + + + + + + + + + + + + +





DAY ON TEST0334

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females(cont...)



Bone Marrow + + + + + + + + + + + + + + + A + + + + + + + + +.........................................................................................................................................................................................................

Lymph Node +.........................................................................................................................................................................................................


Lymph Node, Mesenteric + + + + + + + + + + + + + M + + + + + + + + + + +Hyperplasia, Lymphoid 2 3 1 1 2 2

.........................................................................................................................................................................................................

Spleen + + + + + + + + + + + + + + + A + + + + + + + + +Hematopoietic Cell Proliferation 2 2 2 2Hyperplasia, Lymphoid 3 2 2 2 2

.........................................................................................................................................................................................................

Thymus + + + + + + + + + + + + + A + + + + + + + + + + +Bacterium XForeign Body XHyperplasia, Lymphoid 2 2Necrosis 4


Mammary Gland + + + + + + + + + + + + + + + M + + + + + + + + +Alveolus, Hyperplasia 2

.........................................................................................................................................................................................................





DAY ON TEST0334

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females(cont...)


Skin + + + + + + + + + + + + + + + + + + + + + + + + +


Bone +.........................................................................................................................................................................................................

Bone, Femur + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Skeletal Muscle + + + + + + + + + + + + + + + + + + + + + + + + +

NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + + + + + + + + + + + + + + + + + + + + + + + + +Gliosis

.........................................................................................................................................................................................................


Brain, Cerebrum + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1Mineralization 1


Lung + + + + + + + + + + + + + + + + + + + + + + + + +Bacterium X





DAY ON TEST0334

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females(cont...)


Mediastinum, Foreign Body XMediastinum, Necrosis 3

.........................................................................................................................................................................................................

Nose + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Trachea + + + + + + + + + + + + + + + + + + + + + + + + +


Eye + + + + + + + + + + + + + A + A + + + + + + + + +.........................................................................................................................................................................................................

Harderian Gland + + + + + + + + + + + + + + + + + + + + + + + + +

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + + + + + + + + + + + + + + + + + + + + + + + + +Casts Protein 1Infiltration Cellular, Lymphocyte 1 1 1 2 1 1Metaplasia, Osseous 1

.........................................................................................................................................................................................................

Urinary Bladder + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1 1 1





DAY ON TEST0334

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0336

0333

.................................................................................................................................................................



00300

00301

00302

00303

00304

00317

00325

00326

00363

00364

00403

00429

00430

00445

00451

00483

00505

00506

00507

00508

00529

00544

00545

00546

00548

females(cont...)



Esophagus + + 27Adventitia, Necrosis 1 2.0

.........................................................................................................................................................................................................

Gallbladder + + 26.........................................................................................................................................................................................................

Intestine Large, Cecum + + 27Hyperplasia, Lymphoid 2 2.0

.........................................................................................................................................................................................................

Intestine Large, Colon + + 26.........................................................................................................................................................................................................

Intestine Large, Rectum + + 27Hyperplasia, Lymphoid 1 2.0

.........................................................................................................................................................................................................

Intestine Small, Duodenum + + 27.........................................................................................................................................................................................................

Intestine Small, Ileum + + 27.........................................................................................................................................................................................................

Intestine Small, Jejunum + + 27.........................................................................................................................................................................................................

Liver + + 27Inflammation, Chronic Active 2 1.0Tension Lipidosis 2 5 1.6Vacuolization Cytoplasmic 4 1.0

.........................................................................................................................................................................................................





DAY ON TEST0335

0326

.................................................................................................................................................................



00550

00673 * TOTALS


Pancreas + + 27.........................................................................................................................................................................................................

Salivary Glands + + 27Infiltration Cellular, Lymphocyte 1 14 1.1

.........................................................................................................................................................................................................

Stomach, Forestomach + + 27.........................................................................................................................................................................................................

Stomach, Glandular + + 27


Blood Vessel + + 27.........................................................................................................................................................................................................

Heart + + 27Bacterium 1Pericardium, Necrosis 1 2.0


Adrenal Cortex + + 27Subcapsular, Hyperplasia 1 1 25 1.2

.........................................................................................................................................................................................................

Adrenal Medulla + + 27.........................................................................................................................................................................................................

Islets, Pancreatic + + 27.........................................................................................................................................................................................................





DAY ON TEST0335

0326

.................................................................................................................................................................



00550

00673 * TOTALS


Parathyroid Gland + + 22Cyst 1 1.0

.........................................................................................................................................................................................................

Pituitary Gland + + 27.........................................................................................................................................................................................................

Thyroid Gland + + 27Cyst 1 1.0Degeneration 2 1.0Ectopic Thymus 2


Tissue NOS 1

GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + + 26.........................................................................................................................................................................................................

Ovary + + 27Cyst 1 1 1.0

.........................................................................................................................................................................................................

Uterus + + 27Infiltration Cellular, Polymorphonuclear 3 2.3Endometrium, Hyperplasia, Cystic 4 2.0Lumen, Dilatation 1 12 1.3

.........................................................................................................................................................................................................

Vagina + + 27





DAY ON TEST0335

0326

.................................................................................................................................................................



00550

00673 * TOTALS



Bone Marrow + + 26.........................................................................................................................................................................................................

Lymph Node 1.........................................................................................................................................................................................................

Lymph Node, Mandibular + + 27.........................................................................................................................................................................................................

Lymph Node, Mesenteric + + 26Hyperplasia, Lymphoid 6 1.8

.........................................................................................................................................................................................................

Spleen + + 26Hematopoietic Cell Proliferation 4 2.0Hyperplasia, Lymphoid 5 2.2

.........................................................................................................................................................................................................

Thymus + + 26Bacterium 1Foreign Body 1Hyperplasia, Lymphoid 2 2.0Necrosis 1 4.0


Mammary Gland + + 26Alveolus, Hyperplasia 1 2.0

.........................................................................................................................................................................................................





DAY ON TEST0335

0326

.................................................................................................................................................................



00550

00673 * TOTALS


Skin + + 27


Bone 1.........................................................................................................................................................................................................

Bone, Femur + + 27.........................................................................................................................................................................................................

Skeletal Muscle + + 27

NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + + 27Gliosis 3 1 3.0

.........................................................................................................................................................................................................

Brain, Cerebellum + + 27.........................................................................................................................................................................................................

Brain, Cerebrum + + 27Infiltration Cellular, Lymphocyte 1 1.0Mineralization 1 1.0


Lung + + 27Bacterium 1





DAY ON TEST0335

0326

.................................................................................................................................................................



00550

00673 * TOTALS


Mediastinum, Foreign Body 1Mediastinum, Necrosis 1 3.0

.........................................................................................................................................................................................................

Nose + + 27.........................................................................................................................................................................................................

Trachea + + 27


Eye + + 25.........................................................................................................................................................................................................

Harderian Gland + + 27

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + + 27Casts Protein 1 1.0Infiltration Cellular, Lymphocyte 6 1.2Metaplasia, Osseous 1 1.0

.........................................................................................................................................................................................................

Urinary Bladder + + 27Infiltration Cellular, Lymphocyte 1 4 1.0





DAY ON TEST0335

0326

.................................................................................................................................................................



00550

00673 * TOTALS



Esophagus + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Gallbladder + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Intestine Large, Cecum + + + + + + + + + + + + + + + + + + + + + + A A +Hyperplasia, Lymphoid 2 2 2Epithelium, Hyperplasia 2

.........................................................................................................................................................................................................

Intestine Large, Colon + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Intestine Large, Rectum + + + + + + + + + + + + + + + + + + + + + + + + +Hyperplasia, Lymphoid 3

.........................................................................................................................................................................................................

Intestine Small, Duodenum + + + + + + + + + + + + + + + + + + + + + + A A +.........................................................................................................................................................................................................

Intestine Small, Ileum + + + + + + + + + + + + + + + + + + + + + + A A +.........................................................................................................................................................................................................

Intestine Small, Jejunum + + + + + + + + + + + + + + + + + + + + + + A A +.........................................................................................................................................................................................................

Liver + + + + + + + + + + + + + + + + + + + + + + + + +Hematopoietic Cell ProliferationInflammation, Chronic Active 1Necrosis 1Tension Lipidosis 1 1 1 1 2 1 1Vacuolization Cytoplasmic 1 1





DAY ON TEST0334

0334

0337

0337

0339

0339

0336

0336

0336

0335

0335

0334

0334

0334

0336

0336

0336

0336

0336

0336

0335

0335

0176

0199

0335

.................................................................................................................................................................



00296

00297

00318

00319

00327

00331

00338

00339

00340

00341

00359

00383

00384

00385

00404

00405

00406

00407

00408

00425

00435

00436

00458

00462

00532

females(cont...)


.........................................................................................................................................................................................................

Mesentery +Fat, Necrosis 3

.........................................................................................................................................................................................................

Pancreas + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1Acinar Cell, Degeneration 1

.........................................................................................................................................................................................................

Salivary Glands + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1 1 2 1 1 1 2 1 1

.........................................................................................................................................................................................................


Stomach, Glandular + + + + + + + + + + + + + + + + + + + + + + A A +


Blood Vessel + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Heart + + + + + + + + + + + + + + + + + + + + + + + + +Congestion 3 2Inflammation, Chronic Active 1


Adrenal Cortex + + + + + + + + + + + + + + + + + + + + + + + + +





DAY ON TEST0334

0334

0337

0337

0339

0339

0336

0336

0336

0335

0335

0334

0334

0334

0336

0336

0336

0336

0336

0336

0335

0335

0176

0199

0335

.................................................................................................................................................................



00296

00297

00318

00319

00327

00331

00338

00339

00340

00341

00359

00383

00384

00385

00404

00405

00406

00407

00408

00425

00435

00436

00458

00462

00532

females(cont...)


Subcapsular, Hyperplasia 1 1 1 1 1 1 1 1 2 2 1 2 1 1 1 1 1 2 1 2 1 1 1 1 2.........................................................................................................................................................................................................

Adrenal Medulla + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................


Parathyroid Gland + + + + M + M M + + + + + + + + + + M + M + + + +.........................................................................................................................................................................................................

Pituitary Gland + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Thyroid Gland + + + + + + + + + + + + + + + + + + + + + + + + +


GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + + + M + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Ovary + + + + + + + + + + + + + + + + + + + + + + + + +Cyst 2Bilateral, Cyst 2

.........................................................................................................................................................................................................

Uterus + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Polymorphonuclear 2 2 2Endometrium, Hyperplasia, Cystic 2 2 2 2 2





DAY ON TEST0334

0334

0337

0337

0339

0339

0336

0336

0336

0335

0335

0334

0334

0334

0336

0336

0336

0336

0336

0336

0335

0335

0176

0199

0335

.................................................................................................................................................................



00296

00297

00318

00319

00327

00331

00338

00339

00340

00341

00359

00383

00384

00385

00404

00405

00406

00407

00408

00425

00435

00436

00458

00462

00532

females(cont...)


Lumen, Dilatation 3 2 1 1 1 2 1 1 2 2 2 2 2 1.........................................................................................................................................................................................................

Vagina + + + + + + + + + + + + + + + + + + + + + + + + +


Bone Marrow + + + + + + + + + + + + + + + + + + + + + + A + +Myeloid Cell, Hyperplasia 2 2 3 3

.........................................................................................................................................................................................................

Lymph Node A.........................................................................................................................................................................................................

Lymph Node, Mandibular + + + + + + + + + + + + + + + + + + + + + + A + +Hyperplasia, Lymphoid 2 3

.........................................................................................................................................................................................................

Lymph Node, Mesenteric + + + + + + + + + + + + + + + + + + + + + + + A +Hyperplasia, Lymphoid 2 1 1 2 1 1

.........................................................................................................................................................................................................

Spleen + + + + + + + + + + + + + + + + + + + + + + + + +Hematopoietic Cell Proliferation 3 2 2 4Hyperplasia, Lymphoid 3 2 3 2 3 3 1

.........................................................................................................................................................................................................

Thymus + M + + + + + + + + + + + + + + + + + + + + A A +Hyperplasia, Lymphoid 2 2 2






DAY ON TEST0334

0334

0337

0337

0339

0339

0336

0336

0336

0335

0335

0334

0334

0334

0336

0336

0336

0336

0336

0336

0335

0335

0176

0199

0335

.................................................................................................................................................................



00296

00297

00318

00319

00327

00331

00338

00339

00340

00341

00359

00383

00384

00385

00404

00405

00406

00407

00408

00425

00435

00436

00458

00462

00532

females(cont...)


Mammary Gland + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Skin + + + + + + + + + + + + + + + + + + + + + + + + +


Bone, Femur + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Skeletal Muscle + + + + + + + + + + + + + + + + + + + + + + + + +

NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................


Brain, Cerebrum + + + + + + + + + + + + + + + + + + + + + + + + +Mineralization 1 1 1 1


Lung + + + + + + + + + + + + + + + + + + + + + + A + +.........................................................................................................................................................................................................

Nose + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................





DAY ON TEST0334

0334

0337

0337

0339

0339

0336

0336

0336

0335

0335

0334

0334

0334

0336

0336

0336

0336

0336

0336

0335

0335

0176

0199

0335

.................................................................................................................................................................



00296

00297

00318

00319

00327

00331

00338

00339

00340

00341

00359

00383

00384

00385

00404

00405

00406

00407

00408

00425

00435

00436

00458

00462

00532

females(cont...)


Trachea + + + + + + + + + + + + + + + + + + + + M + + + +


Eye + + + + + + + + + + + + + + + + + + + + + + A + +.........................................................................................................................................................................................................

Harderian Gland + + + + + + + + + + + + + + + + + + + + + + + + +

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + + + + + + + + + + + + + + + + + + + + + + + + +Casts Protein 1 1Hydronephrosis 4Infiltration Cellular, Lymphocyte 1 1 1 1Inflammation, Suppurative 4Nephropathy 4

.........................................................................................................................................................................................................

Ureter +Inflammation, Suppurative 3Lumen, Dilatation 2

.........................................................................................................................................................................................................

Urinary Bladder + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1 1





DAY ON TEST0334

0334

0337

0337

0339

0339

0336

0336

0336

0335

0335

0334

0334

0334

0336

0336

0336

0336

0336

0336

0335

0335

0176

0199

0335

.................................................................................................................................................................



00296

00297

00318

00319

00327

00331

00338

00339

00340

00341

00359

00383

00384

00385

00404

00405

00406

00407

00408

00425

00435

00436

00458

00462

00532

females(cont...)



Esophagus + + 27.........................................................................................................................................................................................................

Gallbladder + + 27.........................................................................................................................................................................................................

Intestine Large, Cecum + + 25Hyperplasia, Lymphoid 3 2.0Epithelium, Hyperplasia 1 2.0

.........................................................................................................................................................................................................

Intestine Large, Colon + + 27.........................................................................................................................................................................................................

Intestine Large, Rectum + + 27Hyperplasia, Lymphoid 1 3.0

.........................................................................................................................................................................................................

Intestine Small, Duodenum + + 25.........................................................................................................................................................................................................

Intestine Small, Ileum + + 25.........................................................................................................................................................................................................

Intestine Small, Jejunum + + 25.........................................................................................................................................................................................................

Liver + + 27Hematopoietic Cell Proliferation 1 1 1.0Inflammation, Chronic Active 1 1.0Necrosis 1 1.0Tension Lipidosis 7 1.1Vacuolization Cytoplasmic 2 3 1.3





DAY ON TEST0335

0312

.................................................................................................................................................................



00533

00609 * TOTALS


.........................................................................................................................................................................................................

Mesentery 1Fat, Necrosis 1 3.0

.........................................................................................................................................................................................................

Pancreas + + 27Infiltration Cellular, Lymphocyte 1 1.0Acinar Cell, Degeneration 1 1.0

.........................................................................................................................................................................................................

Salivary Glands + M 26Infiltration Cellular, Lymphocyte 2 10 1.3

.........................................................................................................................................................................................................


Stomach, Glandular + + 25


Blood Vessel + + 27.........................................................................................................................................................................................................

Heart + + 27Congestion 2 2.5Inflammation, Chronic Active 1 1.0


Adrenal Cortex + + 27





DAY ON TEST0335

0312

.................................................................................................................................................................



00533

00609 * TOTALS


Subcapsular, Hyperplasia 1 1 27 1.2.........................................................................................................................................................................................................

Adrenal Medulla + + 27.........................................................................................................................................................................................................


Parathyroid Gland + + 22.........................................................................................................................................................................................................

Pituitary Gland + + 27.........................................................................................................................................................................................................

Thyroid Gland + + 27


GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + + 26.........................................................................................................................................................................................................

Ovary + + 27Cyst 1 2.0Bilateral, Cyst 1 2.0

.........................................................................................................................................................................................................

Uterus + + 27Infiltration Cellular, Polymorphonuclear 3 2.0Endometrium, Hyperplasia, Cystic 5 2.0





DAY ON TEST0335

0312

.................................................................................................................................................................



00533

00609 * TOTALS


Lumen, Dilatation 14 1.6.........................................................................................................................................................................................................

Vagina + + 27


Bone Marrow + + 26Myeloid Cell, Hyperplasia 4 2.5

.........................................................................................................................................................................................................

Lymph Node 0.........................................................................................................................................................................................................

Lymph Node, Mandibular + M 25Hyperplasia, Lymphoid 2 2.5

.........................................................................................................................................................................................................


.........................................................................................................................................................................................................

Spleen + + 27Hematopoietic Cell Proliferation 4 5 3.0Hyperplasia, Lymphoid 7 2.4

.........................................................................................................................................................................................................

Thymus + M 23Hyperplasia, Lymphoid 3 2.0






DAY ON TEST0335

0312

.................................................................................................................................................................



00533

00609 * TOTALS


Mammary Gland + + 27.........................................................................................................................................................................................................

Skin + + 27


Bone, Femur + + 27.........................................................................................................................................................................................................


NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + + 27.........................................................................................................................................................................................................


Brain, Cerebrum + + 27Mineralization 4 1.0


Lung + + 26.........................................................................................................................................................................................................

Nose + + 27.........................................................................................................................................................................................................





DAY ON TEST0335

0312

.................................................................................................................................................................



00533

00609 * TOTALS


Trachea + + 26


Eye + + 26.........................................................................................................................................................................................................

Harderian Gland + + 27

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + + 27Casts Protein 1 3 1.0Hydronephrosis 1 4.0Infiltration Cellular, Lymphocyte 1 5 1.0Inflammation, Suppurative 1 4.0Nephropathy 1 4.0

.........................................................................................................................................................................................................

Ureter 1Inflammation, Suppurative 1 3.0Lumen, Dilatation 1 2.0

.........................................................................................................................................................................................................

Urinary Bladder + + 27Infiltration Cellular, Lymphocyte 2 1.0





DAY ON TEST0335

0312

.................................................................................................................................................................



00533

00609 * TOTALS



Esophagus + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Gallbladder + + + + + + + + + + + + + + + + + + A + + + + + +.........................................................................................................................................................................................................

Intestine Large, Cecum + + + + + + + + + + + + + + + + A + A + + + + + +Hyperplasia, Lymphoid 2 2

.........................................................................................................................................................................................................

Intestine Large, Colon + + + + + + + + + + + + + + + + + + A + + + + + +.........................................................................................................................................................................................................

Intestine Large, Rectum + + + + + + + + + + + + + + + + + + A + + + + + +.........................................................................................................................................................................................................

Intestine Small, Duodenum + + + + + + + + + + + + + + + + + + A + + + + + +.........................................................................................................................................................................................................

Intestine Small, Ileum + + + + + + + + + + + + + + + + + + A + + + + + +.........................................................................................................................................................................................................

Intestine Small, Jejunum + + + + + + + + + + + + + + + + + + A + + + + + +.........................................................................................................................................................................................................

Liver + + + + + + + + + + + + + + + + + + + + + + + + +Basophilic Focus 2Infiltration Cellular, Lymphocyte 1Tension Lipidosis 1 1 1Vacuolization Cytoplasmic 1 1 1 1 1 1 1 1 1 1

.........................................................................................................................................................................................................

Mesentery +





DAY ON TEST0334

0332

0339

0336

0336

0335

0335

0335

0335

0334

0334

0333

0338

0336

0336

0288

0301

0307

0255

0064

0335

0335

0335

0334

0332

.................................................................................................................................................................



00310

00311

00329

00345

00346

00347

00369

00370

00371

00372

00373

00387

00418

00419

00420

00447

00448

00449

00453

00497

00525

00526

00527

00528

00554

females(cont...)


Hemorrhage 3Fat, Necrosis 4

.........................................................................................................................................................................................................

Pancreas + + + + + + + + + + + + + + + + + + + + + + + + +Cytoplasmic AlterationInfiltration Cellular, Lymphocyte 1 1 1Acinar Cell, Degeneration 2

.........................................................................................................................................................................................................

Salivary Glands + + + + + + + + + + + + + + + + + + + + + + + + +Infiltration Cellular, Lymphocyte 1 1 1 1 1 1 1 1 1

.........................................................................................................................................................................................................


Stomach, Glandular + + + + + + + + + + + + + + + + + + A + + + + + +


Blood Vessel + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Heart + + + + + + + + + + + + + + + + + + + + + + + + +Inflammation, Chronic Active 4


Adrenal Cortex + + + + + + + + + + + + + + + + + + A + + + + + +Subcapsular, Hyperplasia 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 2 2 1 1

.........................................................................................................................................................................................................





DAY ON TEST0334

0332

0339

0336

0336

0335

0335

0335

0335

0334

0334

0333

0338

0336

0336

0288

0301

0307

0255

0064

0335

0335

0335

0334

0332

.................................................................................................................................................................



00310

00311

00329

00345

00346

00347

00369

00370

00371

00372

00373

00387

00418

00419

00420

00447

00448

00449

00453

00497

00525

00526

00527

00528

00554

females(cont...)


Adrenal Medulla + + + + + + + + + + + + + + + + + + A + + + + + +.........................................................................................................................................................................................................


Parathyroid Gland + + M + + + M + + + + + M M + + M + + + + + + + +.........................................................................................................................................................................................................

Pituitary Gland + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Thyroid Gland + + + + + + + + + + + + + + + + + + A + + + + + +Ectopic Thymus X


Tissue NOS +Mediastinum, Abscess 4Mediastinum, Foreign Body X

GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + + + + + + + + + + + + + + + + + + + + + + + + +Degeneration 3

.........................................................................................................................................................................................................

Ovary + + + + + + + + + + + + + + + + + + A + + + + + +Cyst 2Pigmentation 2

.........................................................................................................................................................................................................





DAY ON TEST0334

0332

0339

0336

0336

0335

0335

0335

0335

0334

0334

0333

0338

0336

0336

0288

0301

0307

0255

0064

0335

0335

0335

0334

0332

.................................................................................................................................................................



00310

00311

00329

00345

00346

00347

00369

00370

00371

00372

00373

00387

00418

00419

00420

00447

00448

00449

00453

00497

00525

00526

00527

00528

00554

females(cont...)


Uterus + + + + + + + + + + + + + + + + + + + + + + + + +Edema 3Infiltration Cellular, Polymorphonuclear 2 2 2Endometrium, Hyperplasia, Cystic 2 1 2 2Lumen, Dilatation 2 1 2 1 1 1 1 1

.........................................................................................................................................................................................................

Vagina + + + + + + + + + + + + + + + + M + M + + + + + +


Bone Marrow + + + + + + + + + + + + + + + + + + A + + + + + +Myeloid Cell, Hyperplasia 2

.........................................................................................................................................................................................................

Lymph Node + +Lumbar, Hyperplasia, Lymphoid 2

.........................................................................................................................................................................................................


Lymph Node, Mesenteric + + + + + + + + + + + + + + + + + + + + + + + + +Hyperplasia, Lymphoid 2 2 2 1 2 1

.........................................................................................................................................................................................................

Spleen + + + + + + + + + + + + + + + + + + + + + + + + +Hematopoietic Cell Proliferation 4 3 2 3 2 4 4 2Hyperplasia, Lymphoid 2 1 2 2 2 2

.........................................................................................................................................................................................................

Thymus + + + + + + + + + + + + + + + + + + + + + + + + +Hyperplasia, Lymphoid 2 2Inflammation, Chronic Active 3





DAY ON TEST0334

0332

0339

0336

0336

0335

0335

0335

0335

0334

0334

0333

0338

0336

0336

0288

0301

0307

0255

0064

0335

0335

0335

0334

0332

.................................................................................................................................................................



00310

00311

00329

00345

00346

00347

00369

00370

00371

00372

00373

00387

00418

00419

00420

00447

00448

00449

00453

00497

00525

00526

00527

00528

00554

females(cont...)



Mammary Gland + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Skin + + + + + + + + + + + + + + + + + + + + + + + + +


Bone +.........................................................................................................................................................................................................

Bone, Femur + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Skeletal Muscle + + + + + + + + + + + + + + + + + + + + + + + + +

NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................


Brain, Cerebrum + + + + + + + + + + + + + + + + + + + + + + + + +Compression 2Mineralization 1 1





DAY ON TEST0334

0332

0339

0336

0336

0335

0335

0335

0335

0334

0334

0333

0338

0336

0336

0288

0301

0307

0255

0064

0335

0335

0335

0334

0332

.................................................................................................................................................................



00310

00311

00329

00345

00346

00347

00369

00370

00371

00372

00373

00387

00418

00419

00420

00447

00448

00449

00453

00497

00525

00526

00527

00528

00554

females(cont...)



Lung + + + + + + + + + + + + + + + + + + + + + + + + +AbscessForeign Body XInflammation, Chronic Active 3Necrosis 2

.........................................................................................................................................................................................................

Nose + + + + + + + + + + + + + + + + + + + + + + + + +.........................................................................................................................................................................................................

Trachea + + + + + + + + + + + + + + + + + + + + + + + + +


Eye + + + + + + + + + + + + + + + + A + A + + + + + +.........................................................................................................................................................................................................

Harderian Gland + + + + + + + + + + + + + + + + + + A + + + + + +

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + + + + + + + + + + + + + + + + + + + + + + + + +Casts Protein 1 1Cyst 1GlomerulosclerosisInfiltration Cellular, Lymphocyte 1 1 1 1Nephropathy





DAY ON TEST0334

0332

0339

0336

0336

0335

0335

0335

0335

0334

0334

0333

0338

0336

0336

0288

0301

0307

0255

0064

0335

0335

0335

0334

0332

.................................................................................................................................................................



00310

00311

00329

00345

00346

00347

00369

00370

00371

00372

00373

00387

00418

00419

00420

00447

00448

00449

00453

00497

00525

00526

00527

00528

00554

females(cont...)


.........................................................................................................................................................................................................

Urinary Bladder + + + + + + + + + + + + + + + + + + A + + + + + +Infiltration Cellular, Lymphocyte 1





DAY ON TEST0334

0332

0339

0336

0336

0335

0335

0335

0335

0334

0334

0333

0338

0336

0336

0288

0301

0307

0255

0064

0335

0335

0335

0334

0332

.................................................................................................................................................................



00310

00311

00329

00345

00346

00347

00369

00370

00371

00372

00373

00387

00418

00419

00420

00447

00448

00449

00453

00497

00525

00526

00527

00528

00554

females(cont...)



Esophagus + + 27.........................................................................................................................................................................................................

Gallbladder + A 25.........................................................................................................................................................................................................

Intestine Large, Cecum + A 24Hyperplasia, Lymphoid 2 2.0

.........................................................................................................................................................................................................

Intestine Large, Colon + A 25.........................................................................................................................................................................................................

Intestine Large, Rectum + A 25.........................................................................................................................................................................................................

Intestine Small, Duodenum + A 25.........................................................................................................................................................................................................

Intestine Small, Ileum + A 25.........................................................................................................................................................................................................

Intestine Small, Jejunum + A 25.........................................................................................................................................................................................................

Liver + + 27Basophilic Focus 1 2.0Infiltration Cellular, Lymphocyte 1 1.0Tension Lipidosis 1 4 1.0Vacuolization Cytoplasmic 10 1.0

.........................................................................................................................................................................................................

Mesentery 1





DAY ON TEST0332

0292

.................................................................................................................................................................



00555

00674 * TOTALS


Hemorrhage 1 3.0Fat, Necrosis 1 4.0

.........................................................................................................................................................................................................

Pancreas + A 26Cytoplasmic Alteration 1 1 1.0Infiltration Cellular, Lymphocyte 3 1.0Acinar Cell, Degeneration 1 2.0

.........................................................................................................................................................................................................

Salivary Glands + + 27Infiltration Cellular, Lymphocyte 1 10 1.0

.........................................................................................................................................................................................................


Stomach, Glandular + A 25


Blood Vessel + + 27.........................................................................................................................................................................................................

Heart + A 26Inflammation, Chronic Active 1 4.0


Adrenal Cortex + + 26Subcapsular, Hyperplasia 1 2 24 1.2

.........................................................................................................................................................................................................





DAY ON TEST0332

0292

.................................................................................................................................................................



00555

00674 * TOTALS


Adrenal Medulla + + 26.........................................................................................................................................................................................................


Parathyroid Gland + + 22.........................................................................................................................................................................................................

Pituitary Gland + + 27.........................................................................................................................................................................................................

Thyroid Gland + + 26Ectopic Thymus 1


Tissue NOS 1Mediastinum, Abscess 1 4.0Mediastinum, Foreign Body 1

GENITAL SYSTEM.........................................................................................................................................................................................................

Clitoral Gland + + 27Degeneration 1 3.0

.........................................................................................................................................................................................................

Ovary + + 26Cyst 1 2.0Pigmentation 1 2.0

.........................................................................................................................................................................................................





DAY ON TEST0332

0292

.................................................................................................................................................................



00555

00674 * TOTALS


Uterus + + 27Edema 1 3.0Infiltration Cellular, Polymorphonuclear 3 2.0Endometrium, Hyperplasia, Cystic 1 5 1.6Lumen, Dilatation 8 1.3

.........................................................................................................................................................................................................

Vagina + A 24


Bone Marrow + + 26Myeloid Cell, Hyperplasia 1 2.0

.........................................................................................................................................................................................................

Lymph Node + 3Lumbar, Hyperplasia, Lymphoid 1 2.0

.........................................................................................................................................................................................................

Lymph Node, Mandibular + A 26.........................................................................................................................................................................................................


.........................................................................................................................................................................................................

Spleen + + 27Hematopoietic Cell Proliferation 8 3.0Hyperplasia, Lymphoid 6 1.8

.........................................................................................................................................................................................................

Thymus + + 27Hyperplasia, Lymphoid 2 2.0Inflammation, Chronic Active 1 3.0





DAY ON TEST0332

0292

.................................................................................................................................................................



00555

00674 * TOTALS



Mammary Gland + + 27.........................................................................................................................................................................................................

Skin + + 27


Bone 1.........................................................................................................................................................................................................

Bone, Femur + + 27.........................................................................................................................................................................................................


NERVOUS SYSTEM.........................................................................................................................................................................................................

Brain, Brain Stem + + 27.........................................................................................................................................................................................................


Brain, Cerebrum + + 27Compression 1 2.0Mineralization 2 1.0





DAY ON TEST0332

0292

.................................................................................................................................................................



00555

00674 * TOTALS



Lung + + 27Abscess 4 1 4.0Foreign Body 1Inflammation, Chronic Active 1 3.0Necrosis 1 2.0

.........................................................................................................................................................................................................

Nose + + 27.........................................................................................................................................................................................................

Trachea + + 27


Eye + A 24.........................................................................................................................................................................................................

Harderian Gland + A 25

URINARY SYSTEM.........................................................................................................................................................................................................

Kidney + + 27Casts Protein 2 1.0Cyst 1 1.0Glomerulosclerosis 3 1 3.0Infiltration Cellular, Lymphocyte 4 1.0Nephropathy 3 1 3.0





DAY ON TEST0332

0292

.................................................................................................................................................................



00555

00674 * TOTALS


.........................................................................................................................................................................................................

Urinary Bladder + + 26Infiltration Cellular, Lymphocyte 1 1.0

*** END OF REPORT ***





DAY ON TEST0332

0292

.................................................................................................................................................................



00555

00674 * TOTALS


C Number: ALL€¦ · TDMS No. 20310 - 01 P09: NON-NEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL Date...

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Transcript of C Number: ALL€¦ · TDMS No. 20310 - 01 P09: NON-NEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL Date...