Burger Triangle as a Method for Correcting Inaccuracies of Einthoven Triangle
Transcript of Burger Triangle as a Method for Correcting Inaccuracies of Einthoven Triangle
are compatible with the view that some of the central effects of reserpine are mediated through the release of seroto- nin. I t is conceivable that the beneficial effects of reserpine in mental disturb-ances result from the liberation of sero-tonin. T h e posslbilit~ that reserpine also affects the level of serotonin in brain is now under investigation.
ALFREDPLETSCKER" PARKHURSTA. SHORE
BERNARDB. BRODIE Laboratory of Chemical Pha?rnacology, National H e a ~ t Instztute, Natzonal Institutes of Health, U.S . Publzc Health Seroice, Bethesda, Maryland
References and Notes
1. J. N. Gaddum, Ciba Foundation Symposium, London, ( 1 9 5 3 ) ; D. W. Woolley and E. Shaw, Proc. Natl . Acad. Sci. ( U . S . ) 40, 228 (1954 ) .
2 . P. A. Shore. S. L. Silver. B. B. Brodie, E x ~ e r i -entia, in press.
3 . --, Scie~tce122, 284 ( 1 9 5 9 ) . 4 . T. W. Gaddum. 1. Phvsiol. 121. 15P (1953 ) 5 . ~v . -A . Stoll, ~ c i t w e i z : Arch. Neural. Psychiat.
68, 279 ( 1 9 4 7 ) . 6 . S. Udenfriend and E. 0. Titus, Federatiorz
Proc. 13, 411 ( 1 9 5 4 ) . 7 . S . Udenfriend, H. Weissbach, C. T. Clark, J .
Riol Chem. .. in nress . 8 . R. L. Bowman, P. A. Caulfield, S. Udenfriend,
* Science 122, 32 ( 1 9 5 5 ) . Guest worker from Hoffmann-La Roche, Basel, Switzerland.
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Burger Triangle as a Method for Correcting Inaccuracies of Einthoven Triangle
The triangle of Burger and van Milaan ( I ) was constructed on the basis of the lead vector concept. Burger and van Milaan demonstrated that, in contrast with the triangle of Einthoven, their tri- angle is accurate for calculating cardiac vectorial directions in the frontal plane of a human phantom, regardless of tho- rax form, tissue nonhomogeneity, and ec- centricity of the assumed resultant heart vector. The shape of the Burger triangle is determined by these factors; the three sides are usually unequal (though the influence of the dispersion of the electro- motive forces of the heart is not consid- ered in their concept). T o use such a tri- angle it is necessary, before beginning the usual procedure, to divide the deflections written in the classic limb leads by the length of the corresponding sides: Subse- quent studies (2-8) suggest that the Bur- ger triangle may prove to be more valu- able in clinical electrocardiography than the Einthoven triangle.
The present communication demon-strates the relationship between the shape of the Burger triangle and the inaccuracy of the Eiuthoven triangle in the calcula- tion of the vectorial directions in the frontal plane. A Burger triangle from a
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given subject (human or animal, living or dead, or electrolytic model) could have one of three shapes: equilateral, isosceles, or scalene. If i t is equilateral, ~vhich is exceptional, the Einthoven tri- angle is obviously accurate. If it is not equilateral, the Einthoven triangle is in- accurate. But isosceles or scalene tri-angles can have various accentuations and departures from the equilateral tri- angle.
Figure 1 shows four hypothetical Bur- ger triangles from four subjects; a and b are isosceles, whereas c and d are sca-lene. But b and d depart more from the equilateral than do a and c. For con-venience, a Burger triangle may be trans- formed to a triaxial reference system (just as the Einthoven triangle has been transformed to the triaxial reference sys- tem of Bayley) with parallel transposi- tion of the three sides of the Burger tri- angle toward its geometric center until they coincide. In the same figure four triaxial reference systems-transformed from Burger triangles a, b, c, and d, re-spectively-are shown.
We may designate 1, m, and n as the lengths of the lead vectors RL, RF, and LF of a Burger triangle; and p,, p,, and p , as projections of the heart vector upon I , m, and n. O n the basis of the con-cept that the deflection of an electro-cardiographic lead equals the scalar product of heart vector and the lead vec- tor, one gets
I n order to demonstrate the relation- ship between the Burger triangular shapes in Fig. 1 and the inaccuracy of the Einthoven triangle, it is necessary to as- sume the heart vector to be of equal length in the same arbitrary direction, V (1- 45 ) , in each case. From the ter- minus of V in each triaxial reference sys- tem, perpendicular lines to three sides were drawn; p,, p,, and p , were meas- ured. From the equations, the deflections in LI, LII, and LIII were calculated. T h e values were used to plot the vectorial direction for each subject in the triaxial
Fig. 1. Four hypothetical Burger triangles and corresponding triaxial reference sys-tems. V is the arbitrarily true hmrt vector, which is assumed to be the same in each case.
reference system of Bayley (Fig. 2 ) . The directions a, b, c, and d correspond to rubjects with Burger triangles a, b, c, and d, respectively. I t may be observed that they deviate from V ( the arbitrary "true" direction); that 6 b o V is larger than LaoV , and that L d o V is larger than L c o v .
Fig. 2. The triaxial reference system oi Bayley showing the directions of V and the calculated vrctors.
T h e Einthoven triangle is inaccurate for subjects possessing Burger triangles eithcr of isosceles or scalene shape. The more the triangle departs from the equi- lateral, the more the vectorial direction, calculated in the Einthoven triangle, de- viates from the true one. Use of the Bur- ger triangle permits correction of these potential errors.
ZANGZ. ZAO Ribeira" Preto Medical School, IJnioersity of SZo Paulo, Brazil
References
1. H. C. Burger and J. B. van Slilaan, Brit. Heart 7. 8. 157 ( 1 9 4 6 ) : 9. 154 119471,
2. k.k. Wilson,'j. i f . ~ r b a n t , ' F .D. Johnston, A m . Heart J . 37, 493 ( 1 9 4 9 ) .
3. A. G. T. Beckins. H. C. Burser. 1. B. van Ivlilaan, Brit. Heart J . 12, 339 (1950j.
4 . R. McFee, R. Stow, F. D. Johnston, Circula-tion 6, 21 ( 1 9 5 2 ) .
5 . D . A. Brody and W. E. Romans, Am. Heart J. 45. 263 ( 1 9 5 3 ) .
6 . E.' Frank and C. F. Kay, Circulation 9, i 2 4 ( 1 9 5 4 ) .
7 . 2. 2. Zao, paper presented a t 6th annual meet- ing, Brazil Association for the Advancement of Science, 1954.
8 . -, Z. Kreislaufforschg., in press.
Photochemical Activity of Chloroplasts Isolated from Sugar Beet Infected with Virus Yellows
Sugar beet virus yellows is a serious disease in Europe, where even the mild forms can reduce sugar yields by more than 20 percent ( I ) . The d' ~ s e a ~ e now appears to be widespread in the western United States. Watson and Watson ( 2 )