Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

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Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere

Transcript of Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

Page 1: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

Bundle of fibers

Muscle fiber (muscle cell)

Myofibril Sarcomere

Page 2: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

Myosin filamentActin filament

Relaxed

Partially contracted

Fully contracted

Z- line Z- line

M- disk

A band

H Zone

Page 3: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

Myofibril

I band I bandA band

H ZoneZ line Z line

One Complete Sarcomere

M line

Page 4: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

Actin TroponinTropomyosin

Thin filament organization

Page 5: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

Myosin Tail(-helix coiled coil)

Myosin Head

Myosin light chains(LC1, LC2)

Page 6: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

M-disk Region

Page 7: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.
Page 8: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

ATP binding causes release of myosin from actin

ATP

Page 9: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

Hydrolysis of ATP

ADPPi

Conformational change“cocking of myosin head”

Page 10: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

ADPPi Formation of myosin/actin

crossbridge

Page 11: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

“Power Stroke”

ADP

Pi

Release of ADP and Pi

Page 12: Bundle of fibers Muscle fiber (muscle cell) Myofibril Sarcomere.

High Ca2+

Ca2+

channelCa2+

pump

Ca2+/calmodulin

MLCKMLCK-Ca2+

(active)

Myosin/MLC(relaxed)

Myosin/MLC- P(contraction)

ATP ADP

Pi H2O

MLC phosphatase

MLCK- P(inactive)

MLCK phosphatase

Epinephrinereceptor

Epinephrine

G Protein

Adenylatecyclase

ATP

cAMPR2C2 Protein kinase

(inactive)

2C Protein kinase

(active)

Electrical stimulation

Monocyte membrane


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Warm-Up 1.Based on what you know about Latin root words, what do you think these terms refer to? Sarcomere Sarcoplasm Myofibril Epimysium Perimysium.

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Biology - PapaCambridge · skeletal muscle and not smooth muscle [2] (b) The graph below shows the length of a sarcomere during muscle contraction. 0 1 Length of sarcomere/µm 2 3

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Concept 50.5: The physical interaction of protein …...0.5 µm Fig. 50-25a Bundle of muscle fibers Muscle Nuclei Single muscle fiber (cell) Z lines Plasma membrane Myofibril Sarcomere

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THE INFLUENCE OF TEMPERATURE ON MUSCLE VELOCITY AND … · temperatures. Sarcomere length excursion and muscle shortening velocity, V, were determined from high-speed motion pictures

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Notes: Skeletal Muscle Anatomy. (1) Levels of Organization Muscle (whole organ) Fascicle (portion of muscle) Muscle Fiber (single muscle cell) Myofibril.

Notes: Skeletal Muscle Anatomy. (1) Levels of Organization Muscle (whole organ) Fascicle (portion of muscle) Muscle Fiber (single muscle cell) Myofibril.

Sarcomere mechanics in striated muscles: from molecules to …web.as.uky.edu/Biology/faculty/cooper/Muscle class-UK... · 2017. 3. 3. · REVIEW Sarcomere mechanics in striated muscles:

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MUSCLES AND TENDONS. A transmission electron micrograph showing a longitudinal section of cardiac (heart) muscle, in which the sarcomere structure and.

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wchsmsloan.pbworks.comwchsmsloan.pbworks.com/f/muscles.pdf · Endomysium O Epimysium Fascicle Fiber Myofilament Myofibril O Perimysium Sarco lemma Sarcomere ... first label the following

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What I would like to learn: What I know: Regardingibruce/courses/EE3BB3_2011/EE3BB… · Muscle contraction fibers (slow twitch, fast twitch) Myofibril structure (A band, sarcomere,

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