BSc and MSc projects in the Applied Zoology lab fileBSc and MSc projects in the Applied Zoology lab...
Transcript of BSc and MSc projects in the Applied Zoology lab fileBSc and MSc projects in the Applied Zoology lab...
BScandMScprojectsintheAppliedZoologylabInourlab,weseekanswerstofundamentalzoologicalquestions,suchasdeterminantsofmale(in)fertility,theroleofmito-nuclearinteractionsonmetabolism,thephenotypeandonevolutionarychange.Wealsostudythegeneticsandmaterialpropertiesoftheinsectskin.
Contact:@tu-dresden.de
SPERMBIOLOGY
biz.turnell@
FitnesseffectsofspermageandmetabolismSpermproducereactiveoxygenspecies(ROS)thatcanacceleratetheirownageing.DospermofoldmaleagefasterandproducepooroffspringinDrosophila?Istheresexualselectiononspermageatpre-orpostcopulatorylevel?DospermfromDrosophilahigh-ROSlinesagemorequicklyinmalesandfemales?Reinhardt2007.Quart.ReviewofBiology82:375-393.Pizzarietal.2007.TrendsinEcology&Evolution23:131-140,Sanzetal2010,Aging2:200-223.
cornelia.wetzker@
AutofluorescencelifetimeimagingofcellmetabolismThemetabolicstateofcellsandtissuesisstronglyassociatedwiththeco-enzymeNADH.Weusetheinnovativetechniqueoffluorescencelifetimeimagingmicroscopy(FLIM)tostudythemetabolismofspermstoredinmaleandfemalefruitfliesofwildtypeortransgenicbackground.Wefurtherexplorestructuralaspectsofreproductivetissuesininsects(image:spermstorageorganspermathecaofafemalefruitfly).
cornelia.wetzker@
MolecularbiologyofspermmaturationandmetabolismInthefinalstagesofspermatogenesis,thespermchromatiniscompacteddramaticallytoachieveareducedspermheadsize.Thiseventismediatedthroughthenearlyentirereplacementofnuclearhistoneswiththebasicproteinsprotamines.Weexploretheroleofprotaminesandotherfactorsinthematurationandmetabolismofsperminfruitflies
klaus.reinhardt@
Canspermevolveinresponsetointeractionswithmicrobes?Dosexuallytransmittedmicrobesshapetheevolutionofspermfunction?Donewspeciesevolvebecauseofsexuallytransmitteddiseasesdifferindifferenthabitats?Lockhartetal.1996.Biol.Reviews71:415-471,Reinhardtetal.2016.AnnualRevEcol,Evol,System46:435-459.
INTERACTIONSBETWEENMITOCHONDRIAANDTHENUCLEUS
ralph.dobler@
Ecologyandevolutionofmitochondrial-nuclearinteractions Arepopulationdynamicsaffectedbymito-nuclearinteractions?Whatisthemitochondrialcontributiontobodysize,spermoreggsizeorotherfitness-relatedtraits?Donewspeciesarisebymito-nuclearco-evolution?Dowling2014Biochim.Biophys.Acta1840:1393-1403,Dobleretal.2014JEvol.Biol.27:2012-2034,Hill2016Ecol&Evol6:5831-5842
susanne.voigt@
Physiologyofspecificmitochondrial-nuclearcrosstalksDoesthemismatchedpairingofmitochondrialandnucleargenescausephysiologicalandhealtheffectsinDrosophila.Arephysiologicalmismatcheseradicatedbyselection?Picard&Wallace2016.Mitochondrion30:105-116//Gershonietal.2014,GenomeBiologyandEvolution6:2665-2680.
FUNCTIONOFTHEINSECTCUTICLE
bernard.moussian@
Molecularbiologyandgeneticsoftheinsectcuticle Howdoesthecuticle adoptitsfunctionasabarrieragainstwaterloss,pathogensandxenobiotics,andasanexoskeleton?Methods:CRISPR/Cas9,atomic-force,light,confocal&electronmicroscopy.MoussianB.2016.MolecularModelofSkeletalOrganizationandDifferentiation.In:ExtracellularCompositeMatricesinArthropods(ECohen,BMoussian)Springer,Wangetal.2017:JExpBiol.220:1396-99.Wangetal.2016:ProcBiolSci283:20152994
bernard.moussian@
Sex-biasedexpressionofcuticularenzymesHowdoestheexpressionofspecificgeneschangeduringcuticledevelopment?Howdoestheexpressionofspecificgenesdifferbetweenmalesandfemales?Howdoesgeneexpressionofcuticlegenesdifferacrossorgans?Gangishettietal.2012.EuropeanJournalofCellBiology21:283-295MoussianB.2010.InsectBiochemistryandMolecularBiology40:363-75.
klaus.reinhardt@
GenitaliaevolutionDoesnaturalselectionagainstinfectionaffecttheevolutionofgenitaliashapeandform?Whatisthedisadvantageofcomplexgenitalia?Domaleandfemalegenitaliahavespecificcuticleproperties?Reinhardt2010.Genetica138:119–127,Bar-Onetal.2014,NatureCommunications5:3894,Michelsetal.2015.JRoyalSoc.Interface20141107.
OTHER
klaus.reinhardt@
CulturalhistoryofinsectsWhatisthehistoryofbedbugsinDresdenandSaxony?HowarebedbugsrepresentedinfilmsorTVsitcoms?Howareinsectsrepresentedinchildren'sbooks.ReinhardtK.2014.LiterarischeWanzen.