Brevion: the new small-scale industrial gamma irradiator
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Transcript of Brevion: the new small-scale industrial gamma irradiator
Radiation Physics and Chemistry 63 (2002) 567–569
Brevion: the new small-scale industrial gamma irradiator
Dan McKinney, Robert Perrins, Wayne Gibson, Daniel Levesque*
MDS Nordion, 447 March Road, Kanata, Ont., Canada K2K 1X8
Abstract
The economical processing of low-volume products has been a challenge to the gamma industry since inception,
influencing customers to send their products to contractors or choose alternative technologies. With the introduction of
the Brevion irradiator (patent pending), economical gamma processing of low annual volume product lines is now
possible. This innovative design is specifically targeted at plants processing product volumes of up to 20,000 m3/yr.
Brevion provides good cobalt efficiency and good dose uniformity, thus processing these volumes efficiently and
economically. The Brevion facility has the distinct advantage of a low capital cost, compared to medium-sized
automatic tote plants, while maintaining similar performance. Lead-time for the construction phase is also considerably
shorter, resulting in significantly lower start-up costs. Companies with low-volume product lines can now achieve the
control provided by in-house processing, and eliminate transportation time and costs associated with shipping products
off-site. r 2002 Elsevier Science Ltd. All rights reserved.
Keywords: Batch irradiator; Gamma; Design
1. Introduction
The Brevion ‘‘cartridge’’ irradiator (Fig. 1) is a unique
concept, designed for the low-volume irradiation mar-
ket. It is an extremely versatile and efficient batch
irradiator for irradiating medical and other products.
The Brevion offers processors a low capital cost
alternative to ethylene oxide sterilisation equipment,
by making gamma radiation of low-volume product
lines affordable for in-house processing.
The Brevion is designed to meet the needs of multi-
national medical device manufacturers with small-
volume production in off-shore markets, as well as
contract irradiation service providers in developing
countries facing a small but growing market. This
irradiator has a capacity of 1 million curies (37 PBq)60Co, allowing the ability for significant growth.
1.1. Facility benefits
The Brevion will provide the performance of a typical
medium-scale automatic tote facility but for a much
lower total facility cost. Benefits of a Brevion facility
include:
1. Low capital cost;
2. Short project lead time;
3. Economical processing of small volumes;
4. Flexibility for processing different densities (small
product hold-up, fast product changeover, batch
processing);
5. Minimum direct labour to operate facilityF1
operator per shift; and,
6. Easy and quick dismantling for re-location.
1.2. Brevion performance
The Brevion has the following performance features:
1. Rack capacity: 1 MCi (37 PBq) cobalt
2. Product density range: up to 0.4 g/cm3 (maximum
tote load 88 kg);
3. High product throughput;
4. Competitive processing speed (Fig. 2);
5. Low dose uniformity ratio (DUR);
6. Small shield footprint: 12m� 8m; and,
7. Short installation time: o4weeks on-site
*Corresponding author. Fax: +1-613-592-6815.
E-mail address: [email protected] (D. Lev-
esque).
0969-806X/02/$ - see front matter r 2002 Elsevier Science Ltd. All rights reserved.
PII: S 0 9 6 9 - 8 0 6 X ( 0 1 ) 0 0 5 5 4 - 0
To achieve cost-effective processing with small vo-
lumes, the Brevion utilises a ‘‘batch’’ processing technol-
ogy. Typically, ‘‘batch’’ irradiators can provide good
dose uniformity (low DUR), but they may not provide
adequate throughput or economical processing, due to
the downtime required for batch change-out.
To overcome this challenge, the Brevion utilises a
double cartridge system. To further simplify design and
increase reliability, the interchangeable cartridges are
simple modular structures, which do not contain any
drive mechanisms.
The pre-loaded tote cartridge is exchanged in less than
5min. To achieve this, the shielded door slides out with
the source pass mechanism in-tow, the un-irradiated
cartridge is then exchanged with the irradiated cartridge.
After the exchange, the source pass moves back into the
chamber with the door closing behind.
To provide optimum tote packing efficiency, two tote
sizes are available; the size best suited for the product
cartons to be processed in the facility is chosen.
To maximise cobalt efficiency, the totes are stacked
two-high creating product-overlapping source geometry.
This minimises the gap between the upper and lower
level product, by eliminating the space required for a
second level roller conveyor. The stacked totes are
circulated once around the single level source pass and
vertically interchanged, then circulated a second time
around the source pass. The vertical interchange of
product is performed inside the cell, thereby reducing
total batch cycle time.
While one cartridge of product is being irradiated, a
single operator can easily unload the second one at the
load/unload station. The load/unload station consists of
a stacker/de-stacker and a ten-tote tilt station, which
separates the loading and unloading activities. The
operator indexes each cartridge row until all the totes
are unloaded and re-loaded with unprocessed product.
Once the whole cartridge is re-loaded, it is moved back
to the interchange position until the current batch is
completed.
Performing both irradiation and cartridge reloading
processes together, translates into very fast cycle times
and allows for the processing of a significant number of
batches per year (Fig. 2).
2. Design features
A reliable PLC with redundant safety interlock
features will monitor the whole cycling process. The
computer control process will be fully validated.
The source pass mechanism will require less main-
tenance than a traditional two-level tote plant since
there are fewer moving components, and only one level
of drives. Maintenance can be performed on the second
cartridge, while outside the shield, without shutting the
irradiator down.
The Brevion facility occupies a very small land area
(less than 31m� 18 m). The shield is only 12 m long-
� 8m wide, as there is no maze.
A Brevion facility, including shield, can be built in a
few short months. The modular irradiator design
provides for shipment of a small number of fully
assembled components. This approach allows the main
assemblies to be effectively shop-tested and optimised
prior to shipment. On-site installation time is reduced to
a few weeks, attributable to the factory-assembly and
pre-testing of modular components.
In today’s economy, the need for creative solutions to
maintain global competitiveness is paramount. Brevion
is designed for the eventuality that the facility may
require relocation after several years, to be better
Fig. 1. Pictorial representation of the Brevion irradiator.
Fig. 2. Total batch processing time.
D. McKinney et al. / Radiation Physics and Chemistry 63 (2002) 567–569568
situated in relation to the end market, regional distribu-
tion centres, or transportation routes.
Relocation of the Brevion is a cost-effective option,
given that the modular equipment is designed for easy
disassembly. The cost of rebuilding a shield on a new site
is relatively low due to its simple rectangular layout and
small footprint.
3. Conclusions
The Brevion irradiator is a full production gamma
irradiator, with small-scale size and a low capital cost,
that provides cost-effective processing for low-volume
product lines. This facility is designed for rapid
installation and commissioning, by greatly shortening
the lead-time between order and start-up. Brevion can be
easily relocated, should the reason for the original
location and/or its processing requirements change over
the life of the facility.
Further reading
Fraser, F., 1993. Radiat. Phys. Chem. 42, 429–434.
Kunstadt, P., Steeves, C., Beaulieu, D., 1993. Radiat. Phys.
Chem. 42, 259–268.
McKinney, D., Perrins, R., 2000. Radiat. Phys. Chem. 57,
569–571.
D. McKinney et al. / Radiation Physics and Chemistry 63 (2002) 567–569 569