BRENDA Tutorial · BRENDA Tutorial •Search for enzyme ... •Classic View (C) •…further...
Transcript of BRENDA Tutorial · BRENDA Tutorial •Search for enzyme ... •Classic View (C) •…further...
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BRENDA Tutorial
• Search for enzyme data• Enzyme Summary Page
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(A)
(B)
(C)
The main search options:
• Quick access (A) • and more specific queries (B)• Classic View (C)• …further details in the corresponding BRENDA tutorials
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Select an
information or
data category
(A)quick access to Enzyme Data
Choose a
search option
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Enter a
search term
and perform
the query
(A)quick access to Enzyme Data
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Select the
entries you are
interested in
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Result page:
Click on the EC
number you are
interested in
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Enzyme Summary Page
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New features on theEnzyme Summary Page
Display of the
classification of
the enzyme within
the EC tree
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New features on theEnzyme Summary Page
the display of the
Word Map is
enlarged
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New features on theEnzyme Summary Page
Display of the
reaction scheme
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New features on theEnzyme Summary Page
New options in
the navigation bar
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the number of
entries is shown
only the information
fields with entries
are highlighted
choose the information
field to be displayed by
clicking the checkbox
the different information
fields, collapsed, are
shown by mouseover of
the header, i.e.
„Functional Parameters“
click here to jump
directly to the
„KM Values“ field
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Click here to go
directly to the specific
search to expand or
limit the results.
New features on theEnzyme Summary Page
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Click here to hide or
display all entries of
the information field
below
Here you can choose
to show or to hide all
entries
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Click here to hide or
display all entries in
the table below
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Click here to print the
information field
below
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In the Organism section
you will find all organisms
expressing the enzyme
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Click on the organism to
be linked to the TaxTree
Explorer (see BRENDA
Tutorial TaxTree)
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For detailed protein
sequence information, click
on the UniProt-ID to display
the complete sequence
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Detailed sequence information
including links to the sequence
database and download options
are shown
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Click on „Amino Acid
Sequences“ or
„Transmembrane Helices“
to get more information on
protein sequences
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Here you find all published
protein sequences, the number
of transmembrane helices etc.
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Jump to „PDB and
Structure Links“ to get
more information on
protein structures
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Detailed information on
protein structure classification
of SCOPe and CATH are
displayed by mouseover
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To display the literature
information click on the
reference-ID…
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…to see the detailed literature
information
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Jump to the Enzyme-Ligand
Interactions to learn about
the substrates, products,
inhibitors, cofactors etc.,
i.e. molecular structures
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Click on to display the
molecular structure
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Click on „Disease“ to
display enzyme-related
disease information,
based on text mining
methods
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For further information
from external databases
click on „Links“