Body Fluids Introduction.docx

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    Minindu Ekanayake[Email address]

    Abstract[Draw your reader in with an engaging abstract. It is typically a short

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    #E$$%$A&

    E'(I&)'ME'*IDI)*s +roup

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    ,,- /-

    ,/-

    Introduction

    ,,- of her body weight 0/ kg 1standard

    male1

    23 liters of water

    /- of his body

    weight

    This lower percent being due to a higher fat

    'eonates contain more water

    than adults4 0,56/- water

    With proportionately more

    extracellular uid (ECF)

    then adults.

    At birth! the amount ofinterstitial 7uid isproportionally three times

    larger than in an adult.

    8y the age of 12 months!

    this has decreased to /-

    which is the adult 9alue.

    1 | 8 o d y : l u i d s

    0,- 56/-

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    *otal body water as a percentage

    of total body weight;*8Wlasma4 93% water;? 0- 1plasma

    solids1leural

    >eritoneal

    Byno9ial

    >ericardial

    #erebrospinal

    Intraocular

    %rinary

    $umen

    +.I. $umen

    Body l!id "ompartments #$0 g male&

    Body l!id "ompartments #$0 g male&

    ' | 8 o d y : l u i d s

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    % ofBody

    (eight

    % of )otalBody

    (ater

    *ol!me#+itres&

    ," 2$ '5 19

    lasma '.5 $.5 3.2

    / 12.0 20.0 .'

    ense ")water

    ! $.5 3.2

    Bone water ! #! 3.2

    )ranscell!lar 1.5 2.5 1.0

    /" 33 55 23

    )B( 0% 100%'2

    liters

    *i+erence in ICF and ECF by ma,or Cations

    and -nions

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    | 8 o d y : l u i d s

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    Intracellular Fluid

    *he Intracellular :luid is composed of at least C/C2 separate tiny

    cellular packages. *he concept of a single united compartment called intracellular

    7uid is clearly articial.

    *he I#: compartment is really a 9irtual compartment considered

    as the sum of this huge number of discontinuous small collections.

    Fow can the term Gintracellular 7uid be used as though it was a

    single body of 7uidH

    *he reason is that though not united physically! the collections

    ha9e e=tremely important unifying similarities which make the I#:

    concept of practical usefulness in physiology. In particular!

    similarities of location! composition and beha9iour4

    o +ocation4 )he distinction between /" and ," is clear

    and is easy to !nderstand4 they are separated by thecell membranes

    o "omposition4 /ntracell!lar !ids are high in potassi!m

    and magnesi!m and low in sodi!m and chloride ionso Beha6io!r4 /ntracell!lar !ids beha6e similarly to

    tonicity changes in the ,"

    8ecause of this physiological usefulness! it is con9enient to talk of

    an idealised I#: as though it were a single real entity. *he use of this

    con9ention allows predictions to be made about what will happen

    with 9arious inter9entions and within limits these are physiologically

    meaningful.

    $ | 8 o d y : l u i d s

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    Extracellular Fluid

    A similar argument applies to the E=tracellular :luid.

    *he E#: is di9ided into se9eral smaller compartments ;e.g.45 plasma!Interstitial 7uid! 7uid of bone and dense connecti9e tissue and

    transcellular 7uid

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    *he IB: bathes all the cells in the body and is the link between the

    I#: and the intra9ascular compartment.

    )=ygen! nutrients! wastes and chemical messengers all pass

    through the IB:. IB: has the compositional characteristics of E#: ;as

    mentioned abo9e< but in addition it is distinguished by its usually

    low protein concentration ;in comparison to plasmalasma is the only ma"or 7uid compartment that e=ists as a real 7uid

    collection all in one location.

    It diers from IB: in its much higher

    protein content and its high bulk 7ow

    ;transport function

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    ,,42, ,,430

    .,;34C