BME 128 Thursday April 14 (1) Chapter 9 (Protein Purification)

Half a Quiz

(2) Lecture: Fibrous ProteinsChapter 4

(3) Twirling around in 3-D: Hemoglobin A Classic Case Example: Sickle Cell Anemia

- pg 441-442

• eCommons site still in the works (sorry!): HW1 email OK

• Reading/Study Summary Weeks 1-3:Protein Basics/Structure: Chp 1+2 + Slides + Chp3 (near-completed)Protein Production/Purification/PTM: Slides + PTMs in Book + Chp9

EXAM WILL FOCUS ON PROTEINS AND METHODOLOGY

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Slide Credit: S. Mosimann

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Slide Credit: S. Mosimann

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Slide Credit: S. Mosimann

HW1 Just to be sure - Rules apply as usual…

Homework Turn-In & Late Policy: Homeworks are due at the specifiedtime. Homeworks turned in late have 5% deducted if turned in within 24hours, and an additional 10% for every additional day late until homeworksare returned or answers are given in class or on-line (generally one weekafter homeworks are turned in). You cannot get credit at all if you submityour homework later than that - therefore you have to contact us prior to thedue date/time if you have a serious circumstance!

Academic Honesty and Integrity: What is Academic Integrity? This question is better answered with how weviolate academic integrity. One prime example is fabrication.Fabrication: In any academic exercise, submitting falsified data includingbibliographic resources and experimental data, or altering gradedcoursework/exams and resubmitting to the instructor for a higher score.Facilitating Academic Dishonesty is a violation, too: One form of this isanswering questions on someone else's exam or doing someone else'shomework for them. Another form is helping another student take a test(allowing them to cheat from you).

See our official University Policy on Academic Integrity for Undergraduate Students

Blood Cell Variants and Malaria

Figure Credit: http://sickle.bwh.harvard.edu/malaria_sickle.html

Blood Cell Variants and Malaria

… Can we understand by looking at the structure?