BMB170 2017 Lecture1 - California Institute of...
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Transcript of BMB170 2017 Lecture1 - California Institute of...
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– 6+,34=0-+/I0FZ+45+4G0'(E0• D<5$,07/$4,$7?+503>0I3=+/40D$37&L5$,<?0<4=05-/.,-./<?0I+-&3=50>/3I0-&+0<-3I$,0-30,+??.?</0?+P+?50
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BMB/BI/CH 170 SYLLABUS Fall 2017 http://saf.bio.caltech.edu/bi170.html
TUES/THUR 10:30 A.M. - 12 NOON 151 Crellin
Instructors Bil Clemons 157 Broad, x1796 [email protected]
Teaching Assistants Inha Cho, x4205, [email protected], 129 Spalding Claudia Jette, x , [email protected], ? Braun Jingzhou Wang, x , [email protected], ? Broad
Suggested Text: “Textbook of Structural Biology” Liljas, Liljas, Piskur et al PROTEINS 09/26 01) Introduction, history and basic chemistry #1CJ 09/28 02) Peptide bonds and secondary structure 10/03 03) Tertiary structure 10/05 04) Hydrophobic effect and stabilizing forces 10/10 05) Stability, folding and chaperones #2IC 10/12 06) Chaperones (cont.) and aggregates; motifs, oligomers, assemblies 10/17 07) Cytoskeleton and symmetrical assemblies 10/19 08) Viruses 10/24 09) Metals, enzymes and nucleotide binding proteins #3IC NUCLEIC ACIDS 10/26 10) Basic Chemistry, DNA/RNA structure 10/31 11) Protein interactions, transcription factors 11/02 12) Transcription factors (cont) and ribosomes 11/07 13) Ribosomes and translation #4CJ
MEMBRANES & LIPIDS 11/09 14) Lipids and biological membranes 11/14 15) Membrane protein synthesis and stability 11/16 16) Membrane proteins continued CARBOHYDRATES 11/21 17) Basic chemistry and CAZy #5JZ 11/23 Thanksgiving Holiday 11/28 18) More glycozymes and biological roles 11/30 19) Lectins and glycobiology 12/01 Last problem set due 5PM. 12/08 Finals due by 5PM. (Bil’s office or ????)
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C! NH
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3.2Å3.8Å
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2.8Å
C!
HN
CO
C!NH
OC
C!NH
OC
C!
HN
CO
