BLUE LIGHT-FILTERING CONTACT LENS PARAMETER CHANGES AFTER MULTI
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INTRODUCTION CONCLUSSIONS RESULTS BLUE LIGHT-FILTERING CONTACT LENS PARAMETER CHANGES AFTER MULTI-PURPOSE SOLUTION CLEANING Chamorro E 1 , Bonnin-Arias C 2 , Ríos-Santos S 3 , Sánchez-Ramos C 4 Aim: Determining the physical compatibility properties (diameter, power, and transmittance) in contact lenses with filters blocking the short-wave length bands after a cleaning process with the multipurpose solution All Clean ® (Avizor), according to the ISO 11981:2010 regulations. 1 Factoria I+D, Spain 2 Alta Eficacia Tecnología, Spain Retinal degenerations are the main cause of blindness in the first world. In Europe, they currently affect millions of people, and it is expected an exponential increase because of the rise in the life expectancy, the greater exposition to light, and the loss of the natural protection meant by the ozone layer. The retinal neuro-degeneration can be prevented, stopped, and treated by means of implanting optical filters to block the of short-wave length radiations of the light spectrum reaching the ocular system. The efficiency of the treatment incorporated in the contact lenses has been shown in experimental studies carried out for 4 years with rats, mice, and rabbits. However, it is necessary to know the biocompatibility of the aseptification, cleaning, and maintenance solutions for this type of contact lenses, and determine the parametrical changes likely to take place in the cleaning process. REFERENCES 1.International Organization for Standardization, Ophthalmic Optics. Contact Lenses. Part 3: Measurement methods. in ISO 18369-3:2006 . Geneva. 2.Mutalib, H.A. and K.C. Lee, Soft Contact Lens Parameter Changes After using the Lens2 (R) Automated Lens Cleaner Machine. Sains Malaysiana, 2010. 39(4): p. 685-688. 3.Crabbe, A. and P. Thompson, Effects of microwave irradiation on the parameters of hydrogel contact lenses. Optometry and Vision Science, 2001. 78(8): p. 610-615. 4.Long W.D., Bauman, R.E., Dandridge, R. & Hagmann, P. 1997. Measured versus labeled parameters of daily disposable contact lenses. International Contact Lens Clinic 24: p.187-197 Corresponding author: [email protected] After the cleaning process with the treatment All Clean®, it is shown a variation in the physical parameters for both types of contact lens materials. However, these changes are not clinically-significant because they are within the tolerance ranges established in the ISO regulations. The maintenance solution for contact lenses All Clean® keeps the physical compatibility properties within an acceptable range. EAOO 2012 “Viability study. Contact lenses to prevent blindness: Maintenance and hygiene products”. AVIZOR in collaboration with Universidad Complutense and Factoria I+D. Supported by Comunidad de Madrid and FEDER funds. DIAMETER Tolerance ISO= ±0.20mm POWER REFRACTION Tolerance ISO=±0.25D SPECTRUM MATERIALS AND METHODS DIAMETER POWER REFRACTION UVB TRANSMITANCE UVA TRANSMITANCE VISIBLE TRANSMITANCE > Variation in CL with no filters > Variation in CL with filters With no variations due to cleaning > Variation in CL without filters > Variation in CL without filters GROUPS OF 10 CONTACT LENSES Hema 55%WC Profilcon A 52%WC Measurement of physical parameters in contact lenses before and after a process of cleaning with the multipurpose solution All Clean Soft: 3 cycles, with 10 cleaning protocols in every cycle, and 3 measure registries (30 cleanings/lens, with intervals of 4 hours) Soft lens analyzers Chiltern (diameter) Spectrophotometer Humphrey System (power and transmittance) 3 Avizor Laboratories, Spain 4 Neuro-Computing and Neuro-Robotics Research Group, University Complutense of Madrid, Spain Fig.6. Diameter variation induced by the cleaning process in lenses with and without uv-blue filters Fig.7. Power variation induced by the cleaning process in lenses with and without uv-blue filters Fig.8. UVB transmittance variation induced by the cleaning process in lenses with and without uv-blue filters Fig.9. UVA transmittance variation induced by the cleaning process in lenses with and without uv-blue filters Fig.10. Visible transmittance variation induced by the cleaning process in lenses with and without uv-blue filters Fig.1. Multipurpose solution All Clean Soft and cleaning process performed in hydrophilic CL. Fig.2. Types and classification of the CL used. Fig.3. Procedure to measure the CL diameter. Fig.4. Procedure to measure the CL power refraction Fig.5. Procedure to measure the CL transmittance. Example of transmission spectrum Diameter (mm) Diameter variation after cleaning (mm) Powe refraction variation after cleaning (D) Powe refraction variation after cleaning (D) UVB Transmitance (%) UVB Transmitance variation after cleaning (%) UVA Transmitance (%) UVA Transmitance variation after cleaning (%) Visible Transmitance (%) Visible Transmitance variation after cleaning (%) CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters Basal After Cleaning Process
Transcript of BLUE LIGHT-FILTERING CONTACT LENS PARAMETER CHANGES AFTER MULTI
INTRODUCTION
CONCLUSSIONS
RESULTS
BLUE LIGHT-FILTERING CONTACT LENS PARAMETER CHANGES AFTER MULTI-PURPOSE SOLUTION CLEANING
Chamorro E1, Bonnin-Arias C2, Ríos-Santos S3, Sánchez-Ramos C4
Aim: Determining the physical compatibility properties (diameter, power, and transmittance) in contact lenses with filters blocking the short-wave length bands
after a cleaning process with the multipurpose solution All Clean ® (Avizor), according to the ISO 11981:2010 regulations.
1 Factoria I+D, Spain 2 Alta Eficacia Tecnología, Spain
Retinal degenerations are the main cause of blindness in the first world. In Europe, they currently affect millions of people, and it is expected an exponential increase because of the rise
in the life expectancy, the greater exposition to light, and the loss of the natural protection meant by the ozone layer. The retinal neuro-degeneration can be prevented, stopped, and
treated by means of implanting optical filters to block the of short-wave length radiations of the light spectrum reaching the ocular system.
The efficiency of the treatment incorporated in the contact lenses has been shown in experimental studies carried out for 4 years with rats, mice, and rabbits. However, it is necessary to
know the biocompatibility of the aseptification, cleaning, and maintenance solutions for this type of contact lenses, and determine the parametrical changes likely to take place in the
cleaning process.
REFERENCES 1.International Organization for Standardization, Ophthalmic Optics. Contact Lenses. Part 3:
Measurement methods. in ISO 18369-3:2006 . Geneva.
2.Mutalib, H.A. and K.C. Lee, Soft Contact Lens Parameter Changes After using the Lens2 (R)
Automated Lens Cleaner Machine. Sains Malaysiana, 2010. 39(4): p. 685-688.
3.Crabbe, A. and P. Thompson, Effects of microwave irradiation on the parameters of hydrogel
contact lenses. Optometry and Vision Science, 2001. 78(8): p. 610-615.
4.Long W.D., Bauman, R.E., Dandridge, R. & Hagmann, P. 1997. Measured versus labeled
parameters of daily disposable contact lenses. International Contact Lens Clinic 24: p.187-197
Corresponding author: [email protected]
After the cleaning process with the treatment All Clean®, it is shown a variation in the physical parameters for both types of contact lens
materials. However, these changes are not clinically-significant because they are within the tolerance ranges established in the ISO regulations.
The maintenance solution for contact lenses All Clean® keeps the physical compatibility properties within an acceptable range.
EAOO 2012
“Viability study. Contact lenses to prevent blindness: Maintenance and
hygiene products”. AVIZOR in collaboration with Universidad Complutense
and Factoria I+D. Supported by Comunidad de Madrid and FEDER funds.
DIAMETER
Tolerance ISO= ±0.20mm
POWER REFRACTION
Tolerance ISO=±0.25D
SPECTRUM
MATERIALS AND METHODS
Basal
Tras ciclo de limpieza
DIAMETER POWER REFRACTION UVB TRANSMITANCE UVA TRANSMITANCE VISIBLE TRANSMITANCE
> Variation in CL with no filters > Variation in CL with filters With no variations due to cleaning > Variation in CL without filters > Variation in CL without filters
GROUPS OF 10
CONTACT LENSES
Hema 55%WC Profilcon A 52%WC
Measurement of physical parameters in contact lenses before and after
a process of cleaning with the multipurpose solution All Clean Soft: 3
cycles, with 10 cleaning protocols in every cycle, and 3 measure
registries (30 cleanings/lens, with intervals of 4 hours)
Soft lens analyzers Chiltern (diameter)
Spectrophotometer Humphrey System (power and transmittance)
3 Avizor Laboratories, Spain 4 Neuro-Computing and Neuro-Robotics Research Group, University Complutense of Madrid, Spain
Fig.6. Diameter variation induced by the cleaning
process in lenses with and without uv-blue filters Fig.7. Power variation induced by the cleaning
process in lenses with and without uv-blue filters
Fig.8. UVB transmittance variation induced by the
cleaning process in lenses with and without uv-blue
filters
Fig.9. UVA transmittance variation induced by the
cleaning process in lenses with and without uv-blue
filters
Fig.10. Visible transmittance variation induced by the
cleaning process in lenses with and without uv-blue
filters
Fig.1. Multipurpose solution All Clean Soft and cleaning
process performed in hydrophilic CL.
Fig.2. Types and classification of the CL used.
Fig.3. Procedure to measure the CL
diameter.
Fig.4. Procedure to measure the CL
power refraction Fig.5. Procedure to measure the CL
transmittance. Example of
transmission spectrum
Dia
mete
r (m
m)
Dia
mete
r variation a
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Pow
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efr
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D)
Pow
e r
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ariation
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UV
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) U
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ariation
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%)
UV
A T
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) U
VA
Tra
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ariation
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%)
Vis
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Tra
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ita
nce
(%
) V
isib
le T
ransm
itance v
ariation
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cle
anin
g (
%)
CL with no uv-blue filters CL with uv-blue filters
CL with no uv-blue filters
CL with uv-blue filters
CL with no uv-blue filters
CL with uv-blue filters
CL with no uv-blue filters
CL with uv-blue filters CL with no uv-blue filters
CL with uv-blue filters
CL with no uv-blue filters
CL with uv-blue filters
CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters CL with no uv-blue filters CL with uv-blue filters
Basal
After Cleaning Process
