Name: Marisa Mellett

Date: February 11, 2013

Analysis

Table 1

Anti-A Serum Anti-B Serum Anti-Rh Serum Blood Type

Slide 1- Mrs. Smith Aggulation No aggulation Aggulation +A

Slide 2- Mr. Jones No aggulation Aggulation No aggulation B

Slide 3- Mr. Green Aggulation Aggulation No aggulation AB

Slide 4- Ms. Brown No aggulation No aggulation No aggulation O

1) Choose one of the following patients:

a) Mr. Smith, Mr. Jones, Mr. Green, Ms. Brown= Mr. Smith

b) Using the information shown in Figure 1 on Blood type and the data recorded in Table 1, What

agglutinogens are present on the patient’s RBC’s? A

c) What ABO agglutinin(s) is/are found in the patient’s Plasma? Anti-B

d) What is the patient’s blood type? A

e) If this patient needed a transfusion, what blood type(s) could this patient safely receive? O,A

f) What blood type(s) could safely receive this patient’s blood?A,AB

2) Below is the information representing the blood type analysis of a new patient (patient X). From the

information obtained, fill out the medical technologist report.

A: Agglutination B: No Agglutination Rh: Agglutination

Medical technologist’s report

ABO Type: A

Rh Type: Positive

3) Compare and Contrast agglutinogens and agglutinins. In the diagram show at least 2 similarities and

2 differences.

Agglutinogens Agglutinins

Differences Similarities Differences

Found on surface of erthrocytes, blood type is

based on

Produced in blood, part of immune system

found in plasma, production is initiated by amount of A and B antigens that enter the body

4) Pretend you went with your class on a medical career field trip to a local hospital. One of the stops

on the visit was to the hospital’s blood lab. The medical technologist at this stop gave a

demonstration of how blood types are determined. Your job is to write a paragraph for the school

newspaper on the visit to the blood lab, summarizing what you’ve learned about how ABO/Rh blood

groups are determined. Write a paragraph and include the title.

THE ANATOMY OF BLOOD TYPING:There are four blood types A, B, AB, and O. A persons blood type

is determined by the presence or absence of aggulutinogens, or antigens. Someone withA antigens

has anti-B antibodies, and a person with B antigens has anti-A antibodies. A person who does not

have A or B antigens has both anti-A and anti-B antibodies. Someone with both A and B antigens

doesn’t have anti-A nor anti-B antibodies. This means that blood type is based on the antigens, not

the antibodies. Your body can receive transfusions of only certain blood types, depending on the

type of blood they have; if incompatible blood types are mixed agglutinaton occurs. Landsteiner and

Wiener discovered that rabbit sera containing antibodies for the red blood cells of the Rhesus

monkey would agglutinate the red blood cells of 5% of Caucasians. Individuals who possess these

antigens are designated Rh+ and those who do not possess these antigens are designated Rh-.

5) List at least 3 situations where blood typing could be used.

a) Blood transfusions

b) Criminal Investigation

c) Paternity test

6) Define Erythroblastosis Fetalis. Hemolytic disease of the newborn is a blood disorder in a fetus or

newborn infant. Can be life threatening.

a) Describe the sequence of events that lead to this condition. A mother and her unborn baby have

incompatable blood types. Meaning that the mother produces antibodies that attack the baby’s

red blood cells.

b) What might be some benefits if the medical profession developed a shot or vaccination that

could desensitize an Rh+ situation?There would be no risk, or harm to the fetus.

7) You are a type A eryhthorocyte placing an ad in the personals and you are seeking a compatible

mate for a long lasting transfusion. Create an ad to be submitted to the newspaper.

I am a TYPE A looking for TYPE A/O. I am so red blooded and just looking for that special cell to share

a long lasting transfusion with.

8) Another important diagnostic tool used by medical technologist is determining a patient’s blood cell

count, for both red blood cells and white blood cells. When this procedure is performed, one

technique used is to take multiple samples and calculate the average. This method of multiple

sampling is a standard procedure in scientific and medical investigations. Discuss why this method is

important in blood typing. It is important to take multiple samples to confirm the results and reduce

the risk of human error.

9) Each year thousands of people contract blood borne diseases. What could be done in a clinical

blood lab to minimize the risk of obtaining or spreading a blood borne disease?You’re your hands

often, wear personal protective clothing (gloves, goggles, gowns, masks), and sanitize contaminated

equipment used in clinical blood lab (2).

10) In a short paragraph, identify what you think may be the next important breakthrough, milestone or

discovery in the study of blood and blood diseases and explain why. If a synthetic blood

substituewas created, those who needed blood in emergency situations would not have to wait for

compatible blood type, or a blood resource to be transported to them.