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Transcript of BIR UK MRI course
BIR UK MRI COURSE 2014Venue: Events Centre, Stewart House, London
CPD: 24 Credits
4 – 7NOVEMBER
2014
More information available soon at www.bir.org.uk
• Room1Primers for the non-specialistsSessionorganisedbyDrDavid
Wilson,ConsultantInterventional
MSKradiologist,OxfordUniversity
HospitalsNHSTrust
• Room2Radiation protectionSessionorganisedbyMrAndy
Rogers,HeadofRadiationPhysics,
NottinghamUniversityHospitals
NHSTrust
Save the date
• Room1Clinical hybrid imaging in oncologySessionorganisedbyDrGopinathGnanasegaran,ConsultantPhysicianinNuclearMedicine,StThomas’Hospital
• Room2Musculoskeletal imagingSessionorganisedbyDrRichardWakefield,ConsultantinRheumatology,StJames’sUniversityHospital
Essentials for the radiology traineeSessionorganisedbyDrHardiMadani,RadiologyRegistrar,RoyalFreeLondonHospitalandDrAusamiAbbas,CardiothoracicRadiologyPostCCTFellow,UniversityHospitalAlberta
Day 2Day 1
BIR ANNUAL CONGRESS 20154–5 NOVEMBER
LONDON
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Save the date
Day 2
WelcomeandthankyouforcomingtotheBritishInstituteofRadiologyUKMRIcourse2014.
Thisbookletcontainstheabstractsandbiographiesforeachspeaker(wheresupplied)
Thismeetinghasbeenawarded24RCRcategoryICPDcredits(6perday).
TheBIRMRIcourseorganisingcommitteeandtheBIRwishyouaveryenjoyableandeducationalexperience.
Certificate of attendance
Yourcertificateofattendancewillbeemailedtoyouwithinthenexttwoweeksonceyouhavecompletedtheonlineeventsurveyat:
https://www.surveymonkey.com/s/MRIcourse2014
BIR Annual Congress 2015: 4–5 November, London
We are most grateful to
for supporting this conference
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Programme Tuesday 4 November
DAY 1: PHYSICS
09:00 Registration and refreshments
Chair: DrMartinGraves,ConsultantClinicalScientist, CambridgeUniversityHospitalsNHSFoundationTrust
09:40 Welcome and introduction
09:45 Basic physics refresher DrIanCavin,MRIPhysicist,NHSTayside
10:15 Principles of gradient echo imaging MrLukaszPriba,ClinicalScientist, RoyalInfirmaryEdinburgh,NHSLothian
10:45 Principles of fast/turbo spin echo imaging DrMartinGraves,ConsultantClinicalScientist, CambridgeUniversityHospitalsNHSFoundationTrust
11:15 Refreshments
11:45 Principles of diffusion weighted imaging MrLukaszPriba,ClinicalScientist, RoyalInfirmaryEdinburgh,NHSLothian
12:15 Imaging options: what do they mean? DrIanCavin,MRIPhysicist,NHSTayside
12:45 Fat/water imaging DrMartinGraves,ConsultantClinicalScientist, CambridgeUniversityHospitalsNHSFoundationTrust
13:15 Lunch
14:00 Osirix - the top 10 tricks DrJohnCurtis,ConsultantRadiologist,UniversityHospitalAintree
14:30 Paediatric MRI = GA DrOwenArthurs,ConsultantPaediatricRadiologist, GreatOrmondStreetHospital
15:00 Why is my image quality poor? DrGeoffCharles-Edwards,PrincipalClinicalScientist, Guy’s&StThomas’NHSFoundationTrust
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15:30 Incidental findings ProfessorDavidLomas,ProfessorofClinicalMRI, UniversityofCambridge
16:00 Refreshments
16:15 Advanced pulse sequences DrGeoffCharles-Edwards,PrincipalClinicalScientist, Guy’s&StThomas’NHSFoundationTrust
16:45 Question and answer
17:15 Close of day________________________________________________________________________
Certificate of attendance
Yourcertificateofattendancewillbeemailedtoyouwithinthenexttwoweeksonceyouhavecompletedtheonlineeventsurveyat:
https://www.surveymonkey.com/s/MRIcourse2014
BIR Annual Congress 2015: 4–5 November, London
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Speaker profiles (where supplied)
Dr Owen ArthursConsultant Paediatric Radiologist, Great Ormond Street Hospital
OwenArthursistheClinicalLeadforPaediatricandPerinatalPostMortemImagingatGreatOrmondStreetHospitalinLondon,fundedbyanNIHRClinicianScientistFellowship.HetrainedinpaediatricsandacademicradiologyinCambridge,developingnewpaediatricMRtechniquesforwhichhewonseveralnationalandinternationalprizes.HewasaclinicallecturerinCambridge,ESOR/ESPRfellowinParis,andlatterlyafellowatGreatOrmondStreetHospitalinLondon.Hismaininterestsarenon-accidentalinjuryandpostmortemimaginginchildren,andhehasco-authoredover45peerreviewedpapers,reviewarticlesandbookchapters.
Dr Ian CavinMRI Physicist, NHS Tayside
DrIanCavinisanMRIphysicistwithNHSTaysideprovidingbothclinicalandresearchsupporttoMRIRadiologyaswellasclinicalandacademicresearchersfromtheUniversitiesofDundeeandStAndrews.Priortohiscurrentposition,IanhascarriedoutresearchattheUniversityofNottinghamSirPeterMansfieldMRICentreinvestigatingthebiologicaleffectsofMRImagneticfieldsassociatedwithwholebodyclinical1.5,3and7TeslaMRIscanners.
Dr Geoff Charles-EdwardsPrincipal Clinical Scientist, Guy’s & St Thomas’ NHS Foundation Trust
Aftertrainingasaclinicalphysicist,GeoffCharles-EdwardsobtainedaPhDinmagneticresonancefromtheInstituteofCancerResearch,beforemovingtoGuy’s&StThomas’Hospitalsin2003whereheisnowPrincipalClinicalScientist.HeisalsoaHEFCE-NIHRSeniorClinicalLecturerandanHonorarySeniorLectureratKing’sCollegeLondon.
Dr John CurtisConsultant Radiologist, University Hospital Aintree
DrJohnCurtishasbeenaconsultantradiologistatUniversityHospitalAintreesince1997.Hehasaninterestinchestradiologyandmedicaleducation.HehasorganisedtheAintreeFRCRcoursessince2002andinthelast5yearshashadextensiveexperienceusingOsiriXoncoursesandforteaching.
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Dr Martin GravesConsultant Clinical ScientistCambridge University Hospitals NHS Foundation trust
MartinGravesisaConsultantClinicalScientistatCambridgeUniversityHospitalsNHSTrustwhereheisHeadofMRphysicsandradiologyIT;heisalsoanAffiliatedLecturerwithintheUniversityofCambridgeClinicalSchool.HehasaBScinphysicsandanMScinmedicalelectronicsfromtheUniversityofLondonandaPhDinMRIfromtheUniversityofCambridge.Hehasover30yearsofexperienceworkinginclinicalandresearchMRIinLondonandCambridge.HeisafellowoftheInstituteofPhysicsandEngineeringinMedicineandtheHigherEducationAcademy.HeisactiveonanumberofnationalandinternationalcommitteesincludingtheClinicalImagingBoardandtheISMRMEducationandAnnualMeetingProgrammeCommittees.Hehasauthoredover140journalarticles/bookchaptersaswellastheawardwinningMRItextbookMRI:fromPicturetoProton,PhysicsMCQsforthePart1FRCR,andco-editorofCarotidDisease:theRoleofImaginginDiagnosisandManagement.HeteachesonanumberofMRIcoursesbothnationallyandinternationallyandhasreceivedISMRMOutstandingTeacherawardsin2006and2011.
Professor David LomasProfessor of Clinical MRI, University of Cambridge
DavidJLomasisqualifiedinengineering,medicineandradiologyandhasbeenProfessorofClinicalMRIinCambridgesince2001.HehasworkedcloselywithAddenbrooke’sHepatologyandLivertransplantationservicesoverthelast25yearsandleadstheclinicalMRIservice.HisresearchinterestsincludenoveldevelopmentsinBodyMRIincludingthehepatobiliaryandGItractandhehelpeddevelopMRelastographywithcolleaguesattheMayoClinic.Hehaspublishedover100peerreviewedpapersandlecturedextensivelyintheseareas.PreviouslysecretaryofISMRM,heiscurrentlyChairoftheBIRMRIcommitteeandamemberofthePHEAGNIRgroup.
Mr Lukasz PribaClinical Scientist, Royal Infirmary Edinburgh, NHS Lothian
AftergraduatingwithanMScinmedicalphysicsfromUniversityofAberdeen,LukaszstartedhistrainingasaclinicalscientistinNinewellsHospital,Dundee,NHSTayside.AftersuccessfullycompletinghistraininginMRIanddiagnosticradiology,hejoinedthemedicalphysicsdepartmentinEdinburghwhereheworksnowasaseniorclinicalscientist.Inhiscurrentpost,hefocusesonsupportanddevelopmentofMRIserviceacrossLothian.
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Abstracts (where supplied)
Basic physics refresherDr Ian Cavin
This30minutebasicMRIphysicsrefresherwillrecaptheessentialphysicsneededtogainaworkingknowledgeofMRI.
Principles of gradient echo imagingMr Lukasz Priba
Educationalaim:Abasicunderstandingofimageformationusinggradientechopulsesequence.
Learningoutcomes:Gradientechoisoneofthebasesofmagneticresonanceimaging.Themajoradvantageofagradientechosequenceissignificantreductioninscantime.Toachievethat,smallflipanglesareused,which,inturn,allowveryshortrepetitiontimestobeused.Afterthistalk,delegateswillbefamiliarwithbasicphysicsprinciplesbehindthepulsesequenceandwillgainknowledgeonhowalteringsequenceparameterswillinfluenceresultantimagecontrast.Finally,thispresentationwilldiscussadvantagesanddisadvantagesofusinggradientechopulsesequencesaswellasgivesomeexamplesoffastimagingsequences.
Principles of fast/turbo spin echo imagingDr Martin Graves
Thefastorturbospinecho(FSE/TSE)pulsesequencewasoriginallydevelopedbyHennigetalasamethodtoreduceacquisitiontimesinT2-weightedimaging.Theimplementationisamodificationofamultiple-echospinechosequenceinthateachechoisnowindividuallyphasedencodedandcontributestotherawdata,ork-space,forasingleimage.ForexampleanFSEsequencemaycreate16echoesthroughtheuseof16refocusingpulsesinasinglerepetitionperiod(TR).Sinceeachechoisindividuallyphaseencodedthetimetocompletethefullk-spaceis16timesquicker.Thisdoeshoweverhaveimplicationsforimagecontrast.Sinceeachechoisacquiredatanincreasingtimefromtheinitialexcitationpulsethetimeoftheechothatisencodednearestthecentreofk-spacedictatesthe“effectiveechotime”TEeff,sincethecentreofk-spacehasthegreatestinfluenceonimagecontrast.Furthermore,sincethesignalisdecayingduetoT2relaxationduringtheacquisitionthereisaninevitableimageblurringassociatedwithFSEacquisitions.Theuseofmultiplerefocusingpulsesalsoincreasesthepowerdeposition(SAR)ofthesequence,whichmayrequirecarefuloptimisationofthesequence.
Attheendofthislecturetheparticipantswillbeexpectedto:• UnderstandthebasicprinciplesofFSEimaging.• AppreciatesomeoftheartifactsandlimitationsofFSE.• ExplainhowFSEsequencescanbeoptimised.
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Furtherreading:McRobbieDW,MooreEA,GravesMJandPrinceMR.MRI:fromPicturetoProton2ndEd.CambridgeUniversityPress.ISBN9780521683845
Principles of diffusion weighted imagingMr Lukasz Priba
Educationalaim:Abasicunderstandingofphysicsprinciplesbehindfunctionalimagingbasedonmolecularmotionofwaterinbodytissues.
Learningoutcomes:Diffusionweightedimaging(DWI)hasbeenestablishedasapowerfultoolinneurodiagnostics,mainlyindetectionofacuteischemicstroke.Further,ithasbeenimplementedtostudyneuralfibertractanatomyandbrainconnectivity.Nowadays,useofDWIhasbeenextendedtoimaginginabdomenandpelvisanditisheavilyutilisedinoncologyimagingfordiagnosisandmonitoringtreatmentresponse.Thislecturewillexplainthemoleculardiffusionofwaterinbodytissuesandphysicalprinciplesthatunderlinediffusioncontrastencoding.ThiswillallowthedelegatestounderstandtherelationshipbetweenMRsignalintensityanddiffusion.Withthebasicprinciplesinmind,arangeofmoresophisticatedtechniquesandapplicationswillbereviewed,discussingadvantagesandpotentialissues.
Imaging options: what do they mean?Dr Ian Cavin
Thispresentationwillbesplitintothreesections.Section1willcoverthephysicsprinciples,followedbytheconstructionofabasicpulsesequenceusedinimaginginSection2.Section3willdescribehowthetimingsofradiofrequency(rf)andgradientpulsescanbeusedtogenerateimageswithdifferentcontrast.
Educationalaims:ToprovidedelegateswithausefulandconciseoverviewoftheMRIprinciplessothattheywillbeabletoapplythisknowledgetogainanunderstandingoftheimagingsequencesusedinroutinediagnosticMRI.
Learningoutcomes:Bytheendofthepresentationdelegateswillbeabletoexplainthebasicprinciplesofhow:• AnMRsignalisgeneratedanddetected.• AnMRimageisformed.• Agradientechoimageisformed.• Aspinechoimageisformed.• Aninversionrecoverysequenceisformed.• T1,T2,T2*andprotondensity(PD)imagesaregeneratedwiththeappropriate
selectionofecho(TE)andrepetitiontime(TR).• ApplythebasicprinciplestounderstandtheothertypesofadvanceMRimaging
sequences.
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Fat/water imagingDr Martin Graves
InvivoMRimagesusuallycontainsignalsfromprotonsinbothwaterandfat.Humanfatisstoredastriglycerideswhichareasubgroupoflipidmolecules.Triglyceridescomprisemultiplegroupsofprotons(CH3,CH2,CH=CHetc)withthenuclearshieldingeffectresultinginarangeofchemicalshifts.Themostabundantresonancecomesfromthemethylene(CH2)groups,whichprecessapproximately3.4ppmlowerthanwater.Intermsofrelaxationtimes,fathastheshortestT1,approximately270msat1.5T,ofanybodytissue.Inthislecturewewillconsidertechniquesthatcanallowustoeithersuppressthesignalfromfatorprovidequalitativeorquantitativemeasurementsoffatcontentinordertoaiddiagnosis.Fatsuppressiontechniquescaneitherbeusedtoimprovethecontrastinanimagebyremovingthehighsignalfromlipids,ortoreducetheartefactsthatarisefromthechemicalshiftbetweenwaterandfat.Fatsensitivetechniquescanalsobeusedtohelpcharacterisefat-containinglesionsandprovidequantitativemeasurementsoforganfatsuchasintheliver.
Attheendofthislecturetheparticipantswillbeexpectedto:• Describetheeffectsofthechemicalshiftbetweenwaterandfat.• Comparevariousmethodsoffatsuppression.• Explaintheprinciplesandapplicationsofchemical-shift-basedimaging
techniques.
Furtherreading:McRobbieDW,MooreEA,GravesMJandPrinceMR.MRI:fromPicturetoProton2ndEd.CambridgeUniversityPress.ISBN9780521683845HorgerW.FatSuppressionintheAbdomen.SiemensMagnetomFlash2007:3;114-119
OsiriX - the top 10 tricksDr John Curtis
OsiriXisafreesourcesoftwareusingApplecomputersandisnowwidelyusedbyradiologiststodisplayDICOMimagesforreporting,teachingandexamining.TherearenumerousactionspossiblewithOsiriXbutinthislecturethetoptentrickswillbecoveredthatwillgetthenoviceupandrunningandtheexperienceduserabletoperformadvancedactionstoaugmentteachingandarchiving.
Paediatric MRI = GADr Owen Arthurs
ThispresentationwillfocusonthecurrentchallengesinperformingMRIexaminationsinsmallchildren.Toachievediagnosticimagesthisoftenneedsthemtoliestilltoreducepatientmotion.Therefore,toobtainhigh-qualityimages,paediatricMRIisfrequentlycarriedoutundersedationorgeneralanaesthesia,butthisisnotwithoutriskandexpense.ThispresentationwillfocusonthecurrentadvantagesanddisadvantageofsedationandanaesthesiaforpaediatricMRI,thecurrentalternativesthatareavailable(includingneonatalcomfortingtechniques,sleepmanipulation,andappropriateadaptationofthephysicalenvironment),aswellasgeneralissuesinpaediatricMRIsuchasRF
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heating.Thereisanincreasingunderstandingonwhatcanbeachievedwithsub-anaestheticdosesoftraditionalanaestheticdrugs,aswellaswhatcanbeachievedwithoutaccesstoanaestheticdrugsatall.Therisk–benefitanalysismustultimatelybetakenonapatient-by-patientbasis,andtothisendshoulddetermineserviceprovisionandtrainingrequirements.ThechoiceofapproachtoappropriatepaediatricMRIismultifactorial,withlimitedscientificevidenceformanyofthecurrentapproaches.
Educationalaims:TohighlightthelimitationsofthedifferentoptionsavailableforpaediatricMRI.
Learningoutcomes:ToappreciatethechallengesfacedindeliveringpaediatricMRIexaminationsandto“broadenthemind”withpossiblesolutions.
References• ArthursOJ,SuryM.AnaesthesiaorsedationforpediatricMRI:advantagesand
disadvantages.CurrentOpinioninAnesthesiology(2013)26:489-494• ArthursOJ,EdwardsAD,AustinTA,GravesMJ,LomasDJ.Thechallengesofneonatal
magneticresonanceimaging.PediatricRadiology(2012)42:1183–1194• EdwardsAD,ArthursOJ.PaediatricMRimagingundersedation:isitnecessary?What
istheevidenceforthealternatives?PediatricRadiology(2011)41:1353–1364• SuryMRJ,HarkerH,BegentJetal.Themanagementofinfantsandchildrenfor
painlessimaging.ClinRadiol(2005)60:731–741
Why is my image quality poor?Dr Geoff Charles-Edwards
Educationalaims:TohighlightthevariousissuesrelatingtoMRimagequality.
Learningoutcomes:AnunderstandingofthereasonsforapoorqualityMRimage.AlthoughitistypicallystraightforwardtoidentifythatthequalityofanMRimageispoor,thereasonsforthisaresometimeslessobviousandnotwellunderstood.ThistalkwillcoverissuessuchasSNR,acquiredversusreconstructedspatialresolution,distortions,T2-blurring,andMRartefactsshowingexamplesandhighlightingapproachestoresolvecommonissues.
Incidental findingsProfessor David Lomas
Thedetectionof“incidental”findingsbydiagnostictestsisanincreasinglycomplexproblem.Thisappliesnotjusttoimagingbuttootherdiagnostictestsandinparticulargenesequencing.Theproblemiscompoundedbyusingdiagnostictestsdesignedforsymptomaticpatientstostudy“healthy”individualsbyeither“screening”proceduresorasapartofresearchstudies.Therearenowmultiplelargepopulationbasedstudiesbeingundertakentolinkthegeneticsofanindividualtotheirphenotypeanddiseaserisk,severalofwhichinvolveimaging-usuallywithMRI(egUKBiobank).
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Incidentalfindingsmaybecategorisedaccordingtotheirsignificanceandtheincidencevarieswidelydependingonthenatureofthetestandthepopulation.Examplesofsignificantfindingsincludeunexpectedasymptomaticbrain,lung,renalorcoloncancers,gallstonesinthecommonbileduct,andacerebralAVM.Recentstudiessuggestincidentalfindingsinasmanyas20%ofstudiesalthough“significant”findingsthatmayadverselyaffecthealthareusuallylessthan5%.
InresearchstudiesthedetectionandmanagementofincidentalfindingsshouldnowbeexplicitlyaddressedduringtheEthicalReviewprocessandparticipantsshouldbeinformedoftherisksandconsequencesofsuchfindings.Thesemightincludetheanxiety,costandrisksrelatedtofurtherinvestigation(eg,brainorliverbiopsy)toachieveadefinitivediagnosis.Inmanycasestherisksoffalsenegativeandfalsepositivesarepoorlyunderstoodandmaynotbeknown.Unexpectedcomplicationsofanincidentalfindingsuchasrefusalforlifeinsuranceoramortgageapplicationareoftennotconsideredorappreciatedinadvance.
RecentpublicconsultationstudiesbytheWellcomeTrusthavemadeclearthatthegeneralpopulationarelargelyunawareoftheseissuesandhaveasimplisticviewofbenefitrelatedtodetectinganddiagnosinganunexpecteddiseaseprocess.ThislackofunderstandingandpubliceducationhasrecentlybeenhighlightedbytherecentCOMAREreportfirmlyadvocatingagainstself-referralCTandotherimagingscreeningservicesbeingofferedbytheprivatesector.
InthepastmanyMRIsiteswouldusetheirstaffandstudentsasvolunteersforMRIresearchstudieswithonlyminimalunderstandingandoversightoftheseissues.ThisisnolongerconsideredacceptableandMRIsitesnowrequireethicalapprovalandwritteninformedconsentforvolunteerstudies,eventotestoutnewsequencevariations,protocolsornewapplications.Informationhastobegiventotheparticipantoutliningtherisksandmanagementofincidentalfindings.Thereisnotyetcompleteconsensusontheseissuesbutthereislargelyagreementthatforparticipantsinscreeningandresearchstudiesthereshouldbe“nosurprises”.
Advanced pulse sequencesDr Geoff Charles-Edwards
Educationalaims:TodescribethebasicprinciplesandkeybenefitsofsomeofthemoreadvancedpulsesequencesavailableonclinicalMRIscanners.
Learningoutcomes:Anunderstandingoftheaimsandlimitationsofsomeofthemoreadvancedpulsesequences.
ThereisacontinuingexpansionofpulsesequencesandtechniquesavailableonclinicalMRIsystems.Thistalkwillintroducethebasicconceptsofsomeoftheseandhighlightareaswheretheyappearstohavesignificantutility.TopicswillincludePROPELLER/BLADE/multi-vaneforreducedmotionartefact,SPACE/CUBE/VISTAforspin-echobased3Dacquisitions,temporalsharingfordynamiccontrast-enhancedMRI,susceptibility-weightedimagingforenhancedsensitivitytomicrobleedsandnewmetalartefactreductionsequences.
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Programme Wednesday 5 November
DAY 2: BODY - GI/HPB
08:45 Registration and refreshments
Chair: ProfessorDavidLomas,ProfessorofClinicalMRI, UniversityofCambridge
09:00 Lecture A - a scientific lecture given by the ‘physicist of the day’ to cover the physics aspects of the subsequent lectures DrGeoffCharles-Edwards,PrincipalClinicalScientist, Guy’s&StThomas’NHSFoundationTrust
09:30 Lecture B - Diffuse liver ProfessorDavidLomas,ProfessorofClinicalMRI, UniversityofCambridge
10:00 Lecture C - Focal liver DrSofiaGourtsoyianni,ConsultantRadiologist, Guy’sandStThomas’NHSFoundationTrust
10:30 Lecture D - MRCP/pancreas DrHelenBungay,ConsultantGastrointestinalRadiologist, OxfordUniversityHospitalsNHSTrust
11:00 Refreshments
11:30 Workshop session 1 - topics A&B and C&D
12:15 Workshop session 2 - topics C&D and A&B
13:00 Lunch
14:00 Lecture E - Upper GI DrAngelaRiddell,ConsultantDiagnosticRadiologist, TheRoyalMarsdenHospital
14:30 Lecture F - Lower GI DrSofiaGourtsoyianni,ConsultantRadiologist, Guy’sandStThomas’NHSFoundationTrust
15:00 Workshop session 3 - topics E&F
15:45 Refreshments
16:15 Panel discussion reviewing complex cases
17:00 Close of day
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Speaker profiles (where supplied)
Dr Geoff Charles-EdwardsPrincipal Clinical Scientist, Guy’s & St Thomas’ NHS Foundation Trust
Seepage4
Professor David LomasProfessor of Clinical MRI, University of Cambridge
Seepage5
Dr Sofia GourtsoyianniConsultant Radiologist, Guy’s and St Thomas’ NHS Foundation Trust
April2012-March2013-ClinicalResearchFellow,DivisionofImagingSciences,King’sCollegeLondon,Guy’sandStThomas’NHSFoundationTrust,London,UK
February2011-February2012-LocumConsultantRadiologist,KonstantopouleionGeneralHospital,Athens,Greece
January2010-January2011-ResearchFellowinCTApplications,DepartmentofComputedTomography,BethIsraelDeaconessMedicalCenter,HarvardMedicalSchool,Boston,USA
January2006-November2009-ResidentinRadiology,DepartmentofRadiology,UniversityHospitalofHeraklion,Crete,Greece
May2004-November2005-InstituteofClinicalRadiology,LudwigMaximilianUniversity,CampusInnenstadtandCampusGrosshadern,Munich,Germany
Dr Helen BungayConsultant Gastrointestinal Radiologist, Oxford University Hospitals NHS Trust
Helenisaconsultantgastrointestinalradiologist,specialisinginhepatobiliaryandpancreaticimaging,attheOxfordUniversityHospitalsNHSTrust.HavingstudiedatStJohn’sCollege,Cambridge,andGreenCollege,Oxford,shedidherradiologytraininginOxford.Helenis,indeed,bigsistertoPeterBungay,ConsultantRadiologist,Derby!Butalsomumtotwogorgeousdaughters.ShehasspokenatRSNA,BSGAR,RCRandBIRstudydays,butalsoenjoysfacepaintingatschoolfetes.Sheisveryhappytodiscussinterestingcaseswithpeoplefromdifferenthospitals,andwishalittlemoreofthatcooperationwerepossibleinthetimestrappedNHS.
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Dr Angela RiddellConsultant Diagnostic Radiologist, The Royal Marsden Hospital
DrAngelaRiddellworksasaconsultantdiagnosticradiologistattheRoyalMarsdenHospital.HerworkisinoncologyimagingwithspecialistinterestsinupperGIandhepatobiliarycancer.SheinitiallytrainedinradiologyinOxford&undertookanabdominalimagingFellowshipinTorontobeforeundertakingaradiologyresearchpostattheRoyalMarsdenHospital.ShewasawardedanMDin2007forherresearchdevelopinganMRItechniqueforassessingoperabilityinoesophago-gastriccancer.SheiscurrentlytheleadinvestigatorforaUKmulti-centretrialinvestigatingthetechnique.SheistheleadradiologyrepresentativeontheLondonCancerAllianceforupperGI&hepatobiliarycancers.
Abstracts (where supplied)
Lecture B - Diffuse liverProfessor David Lomas
MRIisofvalueinthedetectionand,increasingly,quantificationofarangeofdiffuseliverdiseases.
Hepatic steatosis or “fatty liver”
Theepidemicofobesityaffectingthewesternworldhasledtotherecognitionthat“fattyliver”isnolongera“normalvariant”butamarkerofpotentiallyimportantdisease,inparticularnon-alcoholicsteato-hepatitis(NASH)whichisexpectedtobecomethemajorcauseofliverfibrosis/cirrhosisandhepatocellularcarcinomainthenextdecade.Regionalvariationofhepaticfat(focaldepositionandsparing)isalsoanincreasingdiagnosticprobleminradiology.MRIprovidesbothconfidentdiagnosisandquantificationofglobalandregionalhepaticsteatosisthroughbothinandoutofphaseimagingand3pointDixontechniques.Inthefuturethesewillbewidelyavailableandarelikelytousefulforthemonitoringofhepaticsteatosisasnewtherapiesemerge.
Hepatic iron – haemochromatosis/haemosiderosis
ItwasrecognisedveryearlyinthedevelopmentofMRIthataccumulationofironintheliverresultsinT2andT2*shortening–reducingtheliversignalrelativetoothertissues.MorerecentlyreliablemethodstoaccuratelyevaluateT2valuesandcorrelatethesewithhepaticironconcentrationhavebeendeveloped.TheseincludeacommercialFDAapprovedofferingdevelopedinAustraliaaswellasseveral“DIY”methodspublishedintheliterature.Theorganpatternofirondepositionmayalsousefultohelpcharacterisetheunderlyingaetiology.
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Liver fibrosis
Traditionally,imagingtestshavebeenrelativelyinsensitivetomildandmoderateliverfibrosisandonlyofrealvalueinestablishedcirrhosiswhenmorphologicalchangeshavedeveloped.Increasinglythisviewisbeingchallengedbynewerfunctionalimagingapproacheswhichincludeelastography(usingbothMRIandUS)andmeasurementsoftheextra-cellularmatrixusingT1methods.Whilstthesearestillbeingvalidated,severalarenowavailablecommercially.Thesetechniquesarealreadyreducingthenumberofdiagnosticliverbiopsiesperformedforsuspectedliverdisease.
Lecture C - Focal liverDr Sofia Gourtsoyianni
Mostcommonlyencounteredfocalliverlesionsinnon-cirrhoticpatientsandtheirtypicalMRIcharacteristicswillbereviewed.DifferentavailableMRIcontrastmechanismsincludinghepatocytespecificcontrastagentsandDWIacquisitionprotocols(optimalbvalues,optimalsequences)willbediscussed.
FocuswillbeplacedonhowDWIandhepatocytespecificcontrastagentscanaidincharacterisationoffocalliverlesionsanddifferentiationbetweenbenignandmalignantlesions(mainlylivermetastases).
Lecture D - MRCP/pancreasDr Helen Bungay
Educationalaims:ThissessionisaimedatconsultantradiologistswhoreportMRCP/MRIpancreas,butdonotholdaspecialistHPBpost,andradiologytrainees.
Thelecture,andtheaccompanyingworkshops,willdiscuss:MRCP:including:• Normalanatomyandvariantsofclinicalimportance(especiallybiliaryvariants
relevanttocholecystectomy);• Artefactsandmimicks;• pathology:calculi;tumour;primarysclerosingcholangitis.
MRIofthepancreas:including:• Pancreatitis;cysticlesions;IgG4relateddisease.
ThesessionwillincludewhentouseMRI,utilityofdifferentsequences,tipsontechniqueandcommonpitfalls,aswellasanoverviewofcommonandimportantpathologies.
Learningoutcomes:Delegatesshouldknowtherelevantanatomyandsequences,understandwhentochooseMRItoimagecertaingroupsofpatients,applytechniquemodificationsforoptimalimages,analysetheimagesinlightofthepossibleartefacts,andsynthesiseareport,knowinglikelycommondiagnoses.
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Lecture E - Upper GIDr Angela Riddell
WithadvancesinsurfacecoiltechnologyandthedevelopmentoffastersequencesitisnowpossibletoachievegoodqualityimagingoftheupperGItract.ThereisanemergingroleforMRIinbothmorphologicalandfunctionalimagingoftheupperGItract.
ThelecturewilldescribehowfunctionalMRIhasbeenevaluatedasanalternativetovideofluoroscopyfortheassessmentofmotilitydisorderswithintheoesophagusforseveralyears.Smallgroupstudieshaveshownthatitshowspotentialtodiagnosemotilitydisorders,suchasgastro-oesophagealrefluxandachalasia.
Researchstudieshavealsodemonstratedtheutilityofthetechniquetolocallystageoesophagogastriccancerandtoassessresponsefollowingneoadjuvanttherapy.Thelecturewillofferguidanceonsequenceselectionandoptimisationtoachievediagnosticqualityimagesinthischallengingarea;highlightthestrengthsandweaknessesofthetechniqueanddemonstratewherethetechniquecouldpotentiallyfitintothestagingalgorithmforpatientswithoesophago-gastriccancer.Itwillalsoshowhowtheintroductionofdiffusionweightedimaginghasenabledthetechniquetobeusedinresponseassessmentfollowingneoadjuvantchemotherapyandchemoradiotherapy.Itwillalsodescribehowthetechniqueisbeingutilisedforradiotherapyplanning.
Lecture F - Lower GIDr Sofia Gourtsoyianni
Pre-operativeMRIoftherectum,usingmainlyhighresolutionT2weightedsequences,hasgainedsignificantaccreditation,especiallyaftertheintroductionoftotalmesorectalexcision(TME)surgeryandneoadjuvanttherapyinthetreatmentregimenofrectalcancer.MRimagingissofartheonlymethodthatcanpreoperativelyidentifypatientsmostlikelytobenefitfromneoadjuvanttherapyaswellasdemonstratehighriskpatientsforlocalrecurrence/metastaticdisease.
StateoftheartMRimagingprotocolstailoredtoallowradiologiststoobtainallnecessaryinformationforappropriatetreatmentdecisionmaking,willbedescribed.MRsignalchangesencounteredinpelvicstructures/tissuesinvolvedbyprimaryrectalcanceratbaselinestagingaswellasaftercompletionofneoadjuvanttreatmentwillbeillustrated.Influenceofimagingfindingsoninitialtherapeuticapproachwillbediscussed.
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Programme Thursday 6 November
DAY 3: NEURO - BRAIN
08:45 Registration and refreshments
Chair: DrMarkRadon,ConsultantNeuroradiologist,TheWaltonCentre
09:00 Lecture A - a scientific lecture to cover the physics aspects of the subsequent lectures DrJonathanAshmore,MRIPhysicist,King’sCollegeHospital
09:30 Lecture B - Demyelination and inflammation DrBrynmorJones,ConsultantNeuroradiologist, ImperialCollegeLondon
10:00 Lecture C - Stroke and mimics DrTufailPatankar,ConsultantNeuroradiologist, LeedsGeneralInfirmary
10:30 Lecture D - Epilepsy DrIanCraven,ConsultantNeuroradiologist, SheffieldTeachingHospitalsNHSFoundationTrust
11:00 Refreshments
11:30 Workshop session 1 - topics A&B and C&D
12:15 Workshop session 2 - topics C&D and A&B
13:00 Lunch
14:00 Lecture E - Tumours DrMarkRadon,ConsultantNeuroradiologist,TheWaltonCentre
14:30 Lecture F - Congenital brain and spine abnormalities in children DrStavrosStivaros,HeadofPaediatricNeuroradiology, RoyalManchesterChildren’sHospitaland NationalInstituteforHealthResearch(NIHR)ClinicianScientist, UniversityofManchester
15:00 Workshop session 3 - topics E&F
15:45 Refreshments
16:15 Panel discussion reviewing complex cases
17:00 Close of day
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Speaker profiles (where supplied)
Dr Jonathan AshmoreMRI Physicist, King’s College Hospital
JonathanAshmoreisanMRIphysicistspecialisinginneuroimagingatKing’sCollegeHospital,London.HedidhisclinicalscientisttrainingatUniversityCollegeLondonHospitalandtheNationalHospitalforNeurologyandNeurosurgery,QueensSquare,London.HisareasofinterestincludeadvancedMRItechniquesforbraintumourimagingandpre-surgicalplanning.
Dr Ian CravenConsultant NeuroradiologistSheffield Teaching Hospitals NHS Foundation Trust
DrCravenisaConsultantNeuroradiologistwithasub-specialtyinterestinpaediatricandneonatalimagingatLeedsGeneralInfirmary.HeisanEducationalLeadforradiologyintheLeedsTeachingHospitalTrustandSpecialistInterestLeadforNeuroradiology.
HeiscurrentlyundertakingaPhDatSheffieldUniversityinMRbrainimaginginyoungadultsandchildren.Duringhisfellowship,heundertookseveralresearchprojectsinepilepsyimagingat3.0Tandhasrecentlysetupa3.0TserviceforimagingrefractoryfocalepilepsyinLeeds.
Dr Brynmor JonesConsultant Neuroradiologist, Imperial College London
2004-2008:DiagnosticradiologytrainingatHammersmithHospitalNHSTrust.2008-2010:PanLondonDiagnosticNeuroradiologyFellowship.2010–present:ConsultantDiagnosticNeuroradiologist,ImperialCollegeHealthcareNHSTrustwithaninterestinpaediatricneuroimaging.
Dr Tufail PatankarConsultant Neuroradiologist, Leeds General Infirmary
DrPatankartrainedinManchesterindiagnosticandinterventionalneuroradiologyandgotPhDinmedicinefromUniversityofManchestermainlyinMRperfusioninbraintumours.HehasbeenaconsultantneuroradiologistintheUKforthelast9years.HestartedtheinterventionalserviceinPrestonandmovedtoLeeds4yearsago.
DrPatankarhasexpertiseinendovasculartreatmentofneurovasculardiseasesespeciallyinbrainaneurysmsandemergingtechnologiesinflowdivertorsandflowdisruptors.
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Hehasaspecialinterestinimaginginstrokeparticularlyinadvancedimagingofstrokeanditsroleintreatmentofstroke.Hehasover100publicationsinpeer-reviewedjournalsandhasbeeninvolvedwithvariousresearchprojectsinbraintumourandbiomarkerimagingandtreatmentofneurovasculardiseases(mainlybrainaneurysmsandstroke).
Hehasbeeninvolvedwithteachingandtrainingmedicalstudents,radiologytraineesandneurologyandneurosurgicaltraineesatUniversityofLeedsandUniversityofManchesterandhasbeeninvolvedwithsupervisingPhD,MDandMScstudentsatUniversityofManchesterandLeeds.
HehasbeenaproctorforwebtreatmentofbrainaneurysmsandbeentrainingneurointerventionsistinUKandEuropeandinaddition,havetrained,supportedandassistedcomplexneurointerventionalcasesinanumberofUKandEuropeancentres.
HeisanAssociateEditorforBJRandmemberofthetrainingandstandardssubcommitteeandacademicsubcommitteeandresearchsubcommitteeofBSNRandreviewerfornumberofnationalandinternationaljournals.
Dr Mark RadonConsultant Neuroradiologist, The Walton Centre
DrRadonqualifiedfromtheUniversityofCambridgemedicalschool,andsubsequentlytrainedinradiologyinSheffield.HetookafellowshipindiagnosticneuroradiologyattheNationalHospitalforNeurologyandNeurosurgeryinLondonandnowworksasaconsultantneuroradiologistatTheWaltonCentreinLiverpool.
Dr Stavros StivarosHead of Paediatric Neuroradiology, Royal Manchester Children’s Hospital and National Institute for Health Research (NIHR) Clinician Scientist, University of Manchester
StavrosStivarosisHeadofPaediatricNeuroradiologyattheRoyalManchesterChildren’sHospital,oneofthelargestspecialistchildren’shospitalsinEuropeandisalsoaNationalInstituteforHealthResearch(NIHR)ClinicianScientistattheUniversityofManchester.Hespecialisesinpaediatricneuroradiologywithaspecialinterestinimaginghydrocephalusandtheimagingofbloodflowandcerebrospinalfluidthroughouttheheadandspineandleadsthepaediatricmulti-parametricimagingresearchgroupwhichcombinesanatomical,physiologicalandfunctionalimaginganalysisinspecificdiseasegroupsincludingneurofibromatosis,autism,epilepsyandchildren’sbraintumours.
DrStivarosholdsadegreeinmedicalphysicsfromUniversityCollegeLondonaswellasamedicaldegreefromtheUniversityofManchesterfromwhereheobtainedhisjointcomputerscience/medicalimagingPhD.Hefrequentlyprovidesevidenceandreportstothecourtandcoroneronissuesrelatedtobrainimaginginchildren.
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Abstracts (where supplied)
Lecture A - a scientific lecture to cover the physics aspects of the subsequent lecturesDr Jonathan Ashmore
ThereareanumberofadvancedMRItechniqueswhichcansignificantlyaidinneuroradiologicaldiagnosisandtreatmentplanning.Theseinclude:• Magneticresonancespectroscopy(MRS)• Diffusionweighted(andtensor)imaging• Dynamicsusceptibilitycontrast(DSC)perfusionimaging• Arterialspinlabelling(ASL)perfusionimaging• Susceptibilityweightedimaging(SWI)• Volumetricimaging(includingCUBE/SPACE/VISTA)
Manyofthesetechniqueshave,however,hadlimiteduptakeintoroutineclinicalusepotentiallyduetodifficultiesintheirimplementationandinterpretation.
MRSmeasurestheprotonNMRsignalforhydrogenatomsattachedtovariousmetabolitesratherthanthoseattachedtothewatermolecule.Theseprotonsresonateatslightlydifferentfrequenciestothoseinthewatermoleculeallowingthemtobedisplayedina“spectra”ofmetabolitesratherthananimage.Theirclinicalapplicationsincludebraintumourdiagnosisandtheidentificationexoticmetabolicspeciesinpaediatricneurologicaldisorders.
DWIweightstheimagetothediffusiverandommotionofwatermoleculesfromwhichmapsoftheapparentdiffusioncoefficient(averagediffusionalongeachdirection)andthefractionalanisotropy(therelativerestrictionofdiffusionalongonedirectioncomparedtotheother)canbecreated.
DSCandASLaretechniqueswhichmeasureperfusionthroughendogenousandexogenousbasedcontrastmethodsrespectively.TheuseofgadoliniuminDSCresultsinincreasedSNRandthereforeshorterimagingtimesbutwiththeassociatedrisksofinjectinggadolinium.InASLspinsarelabelledwithinmajorfeedingarteriesandproducesuppressionofsignalfromthetissueintowhichtheyperfuse.Thesemethodshavefounduseindiagnosisofoncologicalandvascularpathologies.
SWIisaT2*basedimagesequencewhichutilisesthephaseshiftassociatedwithsusceptibilitydifferencesintissuetoenhancethecontrastintheresultantT2*weightedimage.Itsmajoruseistoenhancetheidentificationofbleed.
ThevolumetricfastspinechosequencesCUBE(GE),SPACE(Siemens),VISTA(Philips)utilizeastandard3Dfastspinechotechniquebutwithamodifiedrefocusingpulsetoallowfortheuseoflongechotrains.ThesemethodsreplacestandardT1W,FLAIRandT2Wimagingforcertainapplicationssuchassurgicalplanningwheretrue3Dimagingisbeneficial.
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Lecture B - Demyelination and inflammationDr Brynmor Jones
BothconventionalandadvancedMRItechniquesgiveavaluableinsightintoadiverseandoftendevastatinggroupofdisordersaffectingthecentralnervoussystem(CNS).ThistalkwillconcentrateonthecommonCNSdemyelinatingdisorderslookingatconventionalMRIimagingfeatureswhichincombinationwithclinicalfindingswillhelptoprovideanappropriatedifferentialdiagnosis.Particularattentionwillbegiventoclinicallyisolatedsyndromes(CIS)andmultiplesclerosis(MS)withdiscussionofthespecificityofimagingfindingsrequiredfordiagnosis.Otherprimarydemyelinatingpathologiessuchasneuromyelitisoptica(NMO)willbecoveredemphasisingthedifferentialdiagnosisoflongintramedullaryspinalcordlesions.
DiseasemodifyingtherapiesarenowfrequentlyemployedinMS.JCvirusrelatedprogressivemultifocalleucoencephalophyisadisorderwhichwaspreviouslyonlyseeninseverelyimmunocompromisedHIVpatients.Itis,however,ararebutwellrecognisedcomplicationofsomeofthesediseasemodifyingtreatments.
Wewillreviewsomeofthesecondarydemyelinatingdisorderssuchasacutedisseminatedencephalomyelitis(ADEM)andbrieflydiscussotherCNSinflammatoryconditionssuchasneurosarcoid,Behcet’sandsystemlupuserythromatosis(SLE).
Lecture C - Stroke and mimicsDr Tufail Patankar
TheinterestinMRIasatoolforacutestrokemanagementliesnotonlyinthecapabilityofthistechniquetodetectearlyischemiclesionswithhighsensitivity,butalsointhebreadthofthecerebrovascularpathologyrevealedbysuchimaging.MultimodalMRIcandelineatethepresence,size,location,extentandeffectsofacutebrainischemia,identifythehypoperfusedtissuethatisatriskofinfarction,andshowadditionalfeaturesofthecerebrovascularpathology.MRIcanalsodetectorexcludehemorrhagewithaccuracycomparabletoCT.TheadditionaldiagnosticinformationobtainedwithMRIcouldresultinimprovementsinpatientoutcomesandcost-effectiveness.
ThepresentationwillcovertypicalacutestrokeMRIimagingandthebenefitsofvariousMRsequencesandmagneticresonanceangiographyandperfusion-weightedwhichhastransformedthediagnosisofischemicstrokeimaging.ItaimstodiscussMRappearancesofstroke,thedifficultiesthatcanbeencounteredbytheradiologistsandthevariousotherpathologiesthatcanmimicstroke.
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Lecture D - EpilepsyDr Ian Craven
Imagingpatientswithepilepsycanbeacontentioustopicasoftenwearegivenlimitedinformationyetexpectedtoexcludeamultitudeofpathologies.Inatimepressuredclinicalenvironment,theutilisationofmultiplesequencesisundesirable.Thissessionwillcoverhowtoidentifypatientsthatrequirein-depthexaminationusingdedicatedepilepsyprotocols.Thecommonpathologieswillbediscussedindetailwithmultipleexamplesillustratingwhycertainsequencesaresoimportant.Therareaetiologieswillalsobecovered,allowingtheaudiencetoseeexamplesthattheymaynothavecomeacrossintheirownpractice.Advancedimagingtechniqueswillbediscussedtogivetheaudienceinsightintowhatcanbeachievedandwhatmaybecomeroutinepracticeinthefuture.Thecasesprovidedfortheworkshopwillhelpconsolidatethelecturematerialandalsoallowinformeddiscussionofeverydayproblemsencounteredinclinicalpractice.
Lecture E - TumoursDr Mark Radon
MRIisthecoremodalityforthediagnosisandfollow-upofbraintumours.Thislecturereviewsthemostimportanttypesofprimarybraintumourandtheirimagingcharacteristicsandfeaturesthatdistinguishthemfrommetastatictumours.
Theimportanceofanatomicallocalisationfordifferentialdiagnosisandsurgicalplanningishighlighted,withemphasisonthedifferencesbetweenintra-axialandextra-axialtumours,andbetweensupra-andinfra-tentorialregions.Thefeaturesofavariouslow-andhigh-gradetumoursarecompared,andindicationsforadvancedMRItechniquesdiscussed.Treatmenteffectsarealsoillustrated.Commonpitfallsinbothdiagnosisandfollow-uparehighlighted,andtheindicationsfortheuseoftechniquessuchasMRspectroscopyandperfusionarereviewed.
Thistalkaimstoillustratetheapplicationoftheseprincipleswithseveralcases,andhighlightthefindingswhichassistindiagnosisandfollow-up.
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Programme Friday 7 November
DAY 4: MSK - FUNDAMENTALS
08:45 Registration and refreshments
Chair: DrDavidWilson,ConsultantInterventionalMSKRadiologist, OxfordUniversityHospitalsNHSTrust
09:00 Lecture A - a scientific lecture to cover the physics aspects of the subsequent lectures DrPeterWright,PrincipalMRIPhysicist, SheffieldTeachingHospitalsNHSFoundationTrust
09:30 Lecture B - Cartilage DrBernhardTins,ConsultantMusculoskeletalRadiologist, TheRobertJonesandAgnesHuntOrthopaedicandDistrictHospital
10:00 Lecture C - Bone DrDavidWilson,ConsultantInterventionalMSKRadiologist, OxfordUniversityHospitalsNHSTrust
10:30 Lecture D - Soft tissue tumours DrGeoffHide,ConsultantMusculoskeletalRadiologist, FreemanHospital
11:00 Refreshments
11:30 Workshop session 1 - topics A&B and C&D
12:15 Workshop session 2 - topics C&D and A&B
13:00 Lunch
Chair: DrSarahBurnett,ConsultantMusculoskeletalRadiologist, KingEdwardVIIHospital
14:00 Lecture E - Spine DrWinstonRennie,ConsultantMusculoskeletalRadiologistand HonorarySeniorLecturer,UniversityHospitalsofLeicesterNHSTrust
14:30 Lecture F - Rib lesions DrSarahBurnett,ConsultantMusculoskeletalRadiologist, KingEdwardVIIHospital
15:00 Workshop session 3 - topics E&F
15:45 Refreshments
16:15 Panel discussion reviewing complex cases
17:00 Close of event
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Speaker profiles (where supplied)Dr Sarah BurnettConsultant Musculoskeletal Radiologist, King Edward VII Hospital
SarahBurnettisaConsultantMusculoskeletalRadiologist,formerlyatStMary’sandtheRoyalNationalOrthopaedicHospital,shehasbeeninindependentpracticesince2001.Shequalifiedinmedicinein1985,andstartedherradiologytrainingatStBartholomew’sin1998,becomingaconsultantin1993.SheistheClinicalLeadforQualityat4WaysHealthcare,andhasvastexperienceofteleradiologyandaudit.Shealsohasalargemedicolegalpractice.
Dr Geoff HideConsultant Musculoskeletal Radiologist, Freeman Hospital
DrHidequalifiedinmedicinefromtheUniversityofNewcastleuponTynein1990andwasappointedasaconsultantradiologistatNewcastleUponTyneHospitalsin2002,withaspecialinterestinmusculoskeletalimaging.Heistheleadradiologistfortheboneandsofttissuetumourservice.HeisamemberoftheInternationalSkeletalSociety,currentlythetreasureroftheBritishSocietyofSkeletalRadiologistsandhasactedasanadvisortoNICEandtheDepartmentofHealth.
Dr Winston RennieConsultant Musculoskeletal Radiologist and Honorary Senior Lecturer, University Hospitals of Leicester NHS Trust
DrRennieisaConsultantMusculoskeletalandTraumaInterventionalRadiologistwithanacademicinterestattheLeicesterRoyalInfirmary.HehassetuppioneeringpalliativeinterventionalprocedureslikespinaltumourcoablationandcementoplastyinLeicester.HewasInvolvedincollaborativeresearchprojectswithLoughboroughUniversityandisasupervisoroftwoPhDfellowsinBiomechanicsandinPhysicalsciences.Hehasaspecialinterestinthespineandspinalintervention,havingsetuptheRFKyphoplastyserviceinLeicesterforspinalfractureswithstandardisedQoLoutcomemeasures.
HisspecialdiagnosticinterestisspineMRimaginginSpA,havingcaughtthebugworkingasamusculoskeletalradiologyfellow,intheprestigiousCanadianUniversityofAlbertawithProfessorsWMaksymowychandRLambert.HehasprovidedadvicetotheNationalAnkylosingSpondylitisSociety,withguidanceonsettingupservicesintheUnitedKingdom.HehasdevelopedstandardisedprotocolsinSpAMRimagingandaminvitedinternationalfacultyteachingbothNationallyandInternationallyonhandsonMRIinSpAcoursesforrheumatologistandradiologists.HewasrecentlyappointedontotheNICEGuidelinesDevelopmentGroupforSpAintheUK.
Heisareviewerforpeerreviewedjournalsinawiderangeofspecialitiesrangingfromorthopaedics,trauma,sportsmedicine,RheumatologyandradiologybasedintheUK,NorthAmericaandEurope.Heattempttostimulateaninterestinresearch,highqualityreportingandjournalpublicationsamongsthistrainees.
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HehasbeeninvitedtocontributetoanSpAthinktankheldatPortcullisHouse(HouseofCommons).Inthelittletimehehastospare,heenjoysplayingtheguitar(verybadly)tothewomenwhocaretolisten(hiswifeandyoungdaughters!).
Dr Bernhard TinsConsultant Musculoskeletal Radiologist, The Robert Jones and Agnes Hunt Orthopaedic and District Hospital
DrTinsstudiedphysicsandmedicineinMünster,Germanyandinitiallywantedtobecomeascientist.Howeverhechangedhismindandbeganworkasadoctor,eventuallytrainingasaradiologyregistrarinStoke-on-Trent.DuringthistimehespentsixmonthsinMunich,Germany,inMRimagingand1yearinOswestryasamusculoskeletalfellow.HetookajobasMSKRadiologistinOswestryandhasdevelopedininterestincartilageimagingandspinalimagingandintervention.
Dr David WilsonConsultant Interventional MSK Radiologist, Oxford University Hospitals NHS Trust and President, BIR
DrWilson’sprimaryinterestisintheapplicationofmodernimagingtechniquestodisordersofthelocomotorsystemandspineintervention.Hehasundertakenoriginalworkintheapplicationofdiagnosticultrasoundtojoint,muscle,andsofttissuediseasewithparticularattentiontojointeffusionandcongenitaldysplasiaofthehip.Hehasover20yearsofexperienceinvertebroplastyandistheauthorofpublicationsonmulticentrecontrolledtrialsonthetreatmentofinsufficiencyfractures.HehasestablishedinnovativetrainingcoursesintheUKinmusculoskeletalultrasoundinOxfordandBath.Heteachesinternationallyandisaleaderinthedevelopmentofultrasoundinmusculoskeletaldiseaseandinjectiontechniquesinthespine.HehasconsiderableexperienceinallaspectsofmusculoskeletalimagingandistheEditoroftheprincipletextbookonMSKimaging.AsaformerPresidentoftheBritishSocietyofSkeletalRadiologistandapreviousMedicalDirectoroftheNuffieldOrthopaedicCentrehehaswideclinicalandresearchexperience.HehasbeenamemberoftheBIRsince1982.HewasCommissioningEditoroftheBJR(2011-12)andthenDeputyEditor(2012-2013).HewasVicePresident(ExternalAffairs)from2012-2014.HeiscurrentlyPresidentoftheBIR(2014-16).
Dr Peter WrightPrincipal MRI Physicist, Sheffield Teaching Hospitals NHS Foundation Trust
AfterbeingawardedaPhDinMRIPhysicsattheUniversityofNottingham,DrWrightstartedtrainingtowardsbecomingaclinicalscientistattheUniversityHospitalNorthStaffordshire(UHNS).DrWrightcontinuedhistrainingatLeedsTeachingHospital,wherehewasresidentMRIPhysicisttotheNIHRLeedsMusculoskeletalandBiomedicalResearchUnit(LMBRU)for3years.Sincethen,DrWrightreturnedtoUHNStoestablishanddevelopanMRPhysicsteamandisnowPrincipalMRIPhysicistatSheffieldTeachingHospitalsNHSFoundationTrust.
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Abstracts (where supplied)
Lecture A - a scientific lecture to cover the physics aspects of the subsequent lecturesDr Peter Wright
Educationaims• Introductiontofatsaturationtechniques• AdvantagesanddisadvantagesofSTIR,SPIRandSPAIR• Importanceofshimming• Tipsandtrickstoreduceartefactcausedbymetalimplants• Tounderstandthephysicsbehindthemagicangleeffect
Bytheendofthelecturedelegatesshouldbefamiliarwithfatsuppressiontechniques,includingshorttauinversionrecovery(STIR),spectralpre-saturationwithinversionrecovery(SPIR)andspectraladiabaticinversionrecovery(SPAIR)andtheadvantagesanddisadvantagesofthesetechniques.Theroleofshimmingwillbeintroducedandtheimportanceitplaysinfatsuppression.
MetalimplantscancausesevereartefactinMRimagingtothepointthatimagescanbenon-diagnostic.ThesecondpartofthelecturewilldiscusstipsandtrickstoreducingmetalartefactusingmodifiedstandardMRsequences.
ThemagicangleeffectcancausetheT2oftissuestolengthen.InthecaseoftendonsandothershortT2tissuesthiscanresultinsignalappearingwherenoneisexpected,leadingtothepotentialformis-diagnosis.Herewewilllookatthephysicsbehindthemagicangleeffectandhowtoidentifyit.
Lecture B - CartilageDr Bernhard Tins
Cartilagedamageduetotraumaordegenerationisacauseforjointdegeneration.Thisisassociatedwithpain,lifestylelimitationsandmorbidityandultimatelycost.Theinterestincartilageimaginghasarisenfromtheneedtobetterunderstanddegenerativejointdisease.
Cartilagehasacomplexmicroscopicstructure.Innormalcartilageitsnutritionispurelybydiffusionanditsmetabolicrateandrepaircapacityisthereforelimited.Thenormalanatomyandimagingappearanceofcartilagewillbediscussed.Inrecentyearsimagingtechniqueshavebeendevelopedthatallowtoassesscartilagemetabolismandinfersomeinformationonitsmicrostructure.Conventionalandadvancedimagingtechniquesandtheirrelevancetoroutinepracticeandresearchwillbereviewed.ThisincludescontrastmediumenhancementandT1rhoandT2weightedimaging.
Scoringsystemsforjointdegenerationaresometimesusedbysurgeonsbutaremainlyrelevantforresearch,theywillbrieflybeintroduced.
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Cartilagehasalimitedrepaircapacity.Surgicalrepairtechniques,theirproblemsandcomplicationsandtherelevantimagingappearanceswillbediscussed.Inparticularmicrofracture,chondrocyteimplantationandmosaicplastywillbeexplainedandtheimagingappearancesoutlined.
Whileanumberoftopicswillbecovered,themainaimofthispresentationistoenableageneralradiologisttounderstandwhichaspectsofcartilageimagingarerelevantforroutinepracticeandwhichareasaremainlythedomainsofresearch.Afterthispresentationaradiologistshouldbeabletounderstandtheirorthopaedicsurgeonsandofferguidancetoourorthopaediccolleagues.
Lecture C - Bone Dr David Wilson
Bonesmaybeaffectedbydiseasethatis:-• Lytic• Sclerotic• Mixedlyticandsclerotic• Periostealreaction• Expanded• Deformed• Fractured
Diseasesmaybegroupedas:-• Congenital• Trauma• Infection• Malignant• Metabolic
Imagingisinorderofuse:-• ConventionalRadiographs• CT• MRI• Nuclearmedicine• Ultrasound(thesemethodsarecomplimentary–MRisnotthepanacea)
Commonpitfallsare:-• Missthelyticlesion• Missthediffusemarrowdisease• Misstheperiostealreaction• Misstheundisplacedfracture• Missthesubperiostealerosion• Confuseinsufficiencyfracturewithmalignancy• Forgettothinkofinfection.
Examplesoftheabovewillbepresentedinaquizformat.
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Lecture D - Soft tissue tumoursDr Geoff Hide
ThispresentationwillfocusontheuseofMRIandotherimagingmodalitiesinthediagnosisandstagingofsofttissuetumours.Asystematicapproachtodeterminingadiagnosis,wherepossible,willbediscussedaswilltheadvantagesandlimitationsofMRI.
Lecture E - SpineDr Winston Rennie
Educationalaims:• TounderstandtheprinciplesofspineMRandtheessentialnuancesand
criticaldifferencetoallotherradiologicalimaging-whyspineMRisleftatthebottomofthepile!
• Toplananimagingprotocoltodeliverasmoothpatientthroughputyetnotcompromiseondiagnosticimagequality-quantitynotattheexpenseofquality!
• Todevelopstandardisedclinicallyrelevantnomenclatureandappreciatethediagnosticprocess-stopthetowerofbabel!
• Togainaninsightintospecialisedspineimagingpathwaystailoredtotheclinicalpathology-clinicalstandardisedprotocolsnotstandardprotocols
Learningoutcomes:• Tobeabletoconstructaprotocol/pathwayforspineMRI• Tohaveastandardisedapproachtospinereporting• TobeabletostreamlineservicesandpatientflowthroughtheMR
department• TogainaninsightintoSpAMRIImaging.
Lecture F - Rib lesionsDr Sarah Burnett
Thetalkwillcoverdiverseaspectsofribpathology.LearningoutcomesincludethebenefitsandlimitationsofMRIasamethodofdiagnosingrib,sternalandchestwallpathology.Bytheendofthesession,delegatesshouldexpecttoknowthebestmethodtoimagecertaintypesofribpathology,andlearnsomeoftheclassicalappearances.Thesewillberevisedintheinteractiveandpanelsessions.
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Platinum sponsors
Philipsisadiversifiedhealthandwell-beingcompanyandaworldleaderinhealthcare,lifestyleandlighting.Ourvisionistomaketheworldhealthierandmoresustainablethroughmeaningfulinnovation.
Wedevelopinnovativehealthcaresolutionsacrossthecontinuumofcare,inpartnershipwithcliniciansandourcustomerstoimprovepatientoutcomes,providebettervalue,andexpandaccesstocare.
Aspartofthismissionwearecommittedtofuellingarevolutioninimagingsolutions,designedtodelivergreatercollaborationandintegration,increasedpatientfocus,andimprovedeconomicvalue.Weprovideadvancedimagingtechnologiesyoucancountontomakeconfidentandinformedclinicaldecisions,whileprovidingmoreefficient,morepersonalisedcareforpatients.
TheSiemensHealthcaresectorisoneoftheworld’slargestsupplierstothehealthcareindustryandatrendsetterinmedicalimaging,laboratorydiagnostics,medicalinformationtechnologyandhearingaids.Siemensoffersitscustomersproductsandsolutionsfortheentirerangeofpatientcarefromasinglesource–frompreventionandearlydetectiontodiagnosis,andontotreatmentandaftercare.Byoptimisingclinicalworkflowsforthemostcommondiseases,Siemensalsomakeshealthcarefaster,betterandmorecost-effective.Forfurtherinformationpleasevisit:http://www.siemens.co.uk/healthcare
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FORTHCOMING EVENTS
WELSH BRANCH MEETING: TO REPORT OR NOT TO REPORT....WHAT IS THE ANSWER?11 NOVEMBER 2014
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THE JOURNEY FROM RESEARCH TO PUBLICATION20 NOVEMBER 2014
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THE FUTURE OF RADIOLOGY IN THE NHS: TOP TOPICS FOR INTERVIEWS21 NOVEMBER 2014
LONDON
DIAGNOSTIC RADIOLOGY FOR ADVANCED HEAD AND NECK CANCER PLANNING26 NOVEMBER 2014
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ADVANCES IN RADIOTHERAPY FOR PROSTATE CANCER: FROM THEORY TO PRACTICE12 DECEMBER 2014
CARDIFF
THE SPINE IN HEALTH AND DISEASE21 JANUARY 2015
LONDON
CONTRAST STUDY DAY AND ESSENTIAL PHYSICS FOR FRCR29 - 30 JANUARY 2015
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RADIOLOGY ERRORS6 FEBRUARY 2015
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4TH ANNUAL SPECT/CT SYMPOSIUM: CURRENT STATUS AND FUTURE DIRECTIONS OF SPECT/CT IMAGING23 FEBRUARY 2015
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THE TECHNOLOGY AND USES OF ON-TREATMENT IMAGING IN RADIOTHERAPY24 MARCH 2015
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