Biotechnology In Every School

Carlmont High SchoolBiotechnology 3-year

Program

Carlmont High SchoolBiotechnology 3-year

Program

Tina Doss

[email protected]

Dan Raffa

[email protected]

So you want to start anInnovative Science class.So you want to start an

Innovative Science class.

Goals and Objectives?Target Students?Teacher/Classroom?Cost of Program?Future Pathways?Curriculum?Financial Support?Administrative Support?

Goals and Objectives?Target Students?Teacher/Classroom?Cost of Program?Future Pathways?Curriculum?Financial Support?Administrative Support?

Goals and ObjectivesGoals and Objectives

To better prepare students for higher education?

To better prepare students for industry?

To increase scientific literacy in students?

All of the above.

To better prepare students for higher education?

To better prepare students for industry?

To increase scientific literacy in students?

All of the above.

Target Students?Target Students?

Honor students?Middle 50%

students?Low-level or

high-risk students?

Will you have prerequisites?

Honor students?Middle 50%

students?Low-level or

high-risk students?

Will you have prerequisites?

Teacher / ClassroomTeacher / Classroom

Who will teach the class? Enthusiastic Teacher Willing to learn

Where will it be taught?Designated SpaceStorageComputers?Will you have to share a room?

Timeline for Implementation

Who will teach the class? Enthusiastic Teacher Willing to learn

Where will it be taught?Designated SpaceStorageComputers?Will you have to share a room?

Timeline for Implementation

Cost of ProgramCost of Program

$10,000 - $500,000Length of your programSeries of labsComputers?

$10,000 - $500,000Length of your programSeries of labsComputers?

What is Biotechnology?What is Biotechnology?

Manipulation of living things or their components to benefit

humankind.

Manipulation of living things or their components to benefit

humankind.

Insulin

Carlmont HS Biotechnology Program


Why did this happen?

Bay Area has been a leader in the industry for over 25 years.

Local media such as the San Jose Mercury (December 4, 2002) point to the industry’s desperate need for a well educated workforce and mention in particular the need to draw more minority students into the sciences.

Why did this happen?

Bay Area has been a leader in the industry for over 25 years.

Local media such as the San Jose Mercury (December 4, 2002) point to the industry’s desperate need for a well educated workforce and mention in particular the need to draw more minority students into the sciences.



How did this happen?

Measure G funds

SSP

Ellyn Daugherty, Biotechnology Teacher

Industry Donations

How did this happen?

Measure G funds

SSP

Ellyn Daugherty, Biotechnology Teacher

Industry Donations

Chemistry for Biotechnology Students:

Standard Chemistry with specific Biotech applications. Caffeine Spec Analysis, Quantitative Analysis, Organic & Protein Chemistry

Biotechnology 3 -4

Advanced SLOP, Plant, “How to Videos” Pharmaceutical and Agricultural Biotechnology, Diagnostic Biotechnology, Product Productivity Project

Biotechnology 1-2

SLOP, Scientific Notebook, Lab Safety, DNA/ Protein Purification, Protease Project

Where can students go after:Where can students go after:

ROP Regional Occupational Program (spring/summer program)

Community College (AA Bio-manufacturing)

UC/CSU/Private Universities

ROP Regional Occupational Program (spring/summer program)

Community College (AA Bio-manufacturing)

UC/CSU/Private Universities

Skyline College - BIOMAPS Location

Skyline College - BIOMAPS Location

Bay Area Bioscience Cluster

Bay Area Bioscience Cluster

Birthplace of Biotechnology—Cetus founded in 1971 / Genentech founded in 1976

9 counties, 101 cities, 7,000 square miles of land 900 Life Science Companies 90,000 Employed in Bioscience Directly $6 Billion PayrollAverage wage $68,000 393 marketed products / 400 products in Phase II

and Phase III

Birthplace of Biotechnology—Cetus founded in 1971 / Genentech founded in 1976

9 counties, 101 cities, 7,000 square miles of land 900 Life Science Companies 90,000 Employed in Bioscience Directly $6 Billion PayrollAverage wage $68,000 393 marketed products / 400 products in Phase II

and Phase III

INTRODUCTION TO

BIO SCIENCE (Employability, Life Skills, Ergonomics)

CONTEXTUALIZED BIO SCIENCE LITERACY/

VESL TRAINING(100-150 hours)

ASSISTANT MEDIA PREP

30K – 40K + Benefits

PREPARATION(11-12th grade literacy Training)

ENTRY LEVELTRAINING

(300 hrs of community college credited course)

UPGRADEE MPLOYMENT

ADVANCEEMPLOYMENT

Originally developed byWorkforce Strategy Center

GRUBER & PEREIRA ASSOCIATES, LLC.Workforce and Economic Development Consulting

THE SAN MATEO REGIONAL BIOTECH CAREER LADDER SYSTEM

GRUBER&PEREIRA ASSOCIATESSAN MATEO LABOR COUNCIL

PENINSULA WORKSSKYLINE COLLEGEOHLONE COLLEGE

STATE OF CALIFORNIA – EDDBIO INDUSTRY

PARTNERS

PHARMACEUTICAL MATERIALSSPECIALIST


BIO PROCESS MANUFACTURINGTECHNICIAN

35k – 45k + Benefits

1-3 MONTHS PAID WORK EXPERIENCE($14.00+ per hour)

BIO PROCESS/ASSISTANT MEDIA PREP/ PHARMACEUTICAL MATERIALS

SPECIALIST TRAINING(Biological Sciences, Physical Sciences, Engineering)

(300 hours)

QUALITY CONTROL (QC) ANALYSTTECHNICIAN

40k – 50k + Benefits

ENTRY LEVEL EMPLOYMENT

LABWARE TECH.30K – 40K + Benefits

ASST. FINAL PRODUCT INSPECTOR


MFG. DOCUMENTATIONREVIEWER


LABELING AND PACKAGINGOPERATOR


4 MONTHS UPGRADE TRAININGUPGRADETRAINING

(300 hrs of Chemistry, Biology, GMP, FDA)

PAID WORK EXPERIENCE

SB 70 (Scott) -- Economic Development and Career Technical Education Reform

Initiative

SB 70 (Scott) -- Economic Development and Career Technical Education Reform

InitiativeSenate Bill 70 provides $20 million to the California

Community Colleges. The funds, which became available January 1, 2006, are being used for several

types of projects:

"Quick Start" Partnerships, which will enhance linkages and pathways between secondary schools and selected economic and workforce development initiatives in community colleges

Projects that will grow program capacity and infrastructure

Projects that will strengthen Career and Technical Education sectors at secondary school.

Senate Bill 70 provides $20 million to the California Community Colleges. The funds, which became

available January 1, 2006, are being used for several types of projects:

"Quick Start" Partnerships, which will enhance linkages and pathways between secondary schools and selected economic and workforce development initiatives in community colleges

Projects that will grow program capacity and infrastructure

Projects that will strengthen Career and Technical Education sectors at secondary school.

BIOMAPS Quickstart ProjectBIOMAPS Quickstart Project

Meet industry-driven workforce needs;

Expand certificate programs Develop articulated courses Expand work experience

opportunities, Initiate mentor programs

(BIOMentors), Conduct company tours

(BIOBus), Provide faculty (including

counselors) professional development.

Meet industry-driven workforce needs;

Expand certificate programs Develop articulated courses Expand work experience

opportunities, Initiate mentor programs

(BIOMentors), Conduct company tours

(BIOBus), Provide faculty (including

counselors) professional development.

BIOBus Tour of South San FranciscoBIOBus Tour of South San Francisco

Skyline College and Carlmont High School sponsored a BIO-Bus Tour of the South San Francisco Biotechnology Industry.

Twenty-seven Carlmont Students, toured a circular route through the area with stops at Genentech and Cell Genesys for on-site tours.

The tour ended at Skyline College with activities in the new Science Facilities and lunch in the new Student and Community Center.

Skyline faculty led experiments to provide the students with experiential learning in biotechnology.

Skyline College and Carlmont High School sponsored a BIO-Bus Tour of the South San Francisco Biotechnology Industry.

Twenty-seven Carlmont Students, toured a circular route through the area with stops at Genentech and Cell Genesys for on-site tours.

The tour ended at Skyline College with activities in the new Science Facilities and lunch in the new Student and Community Center.

Skyline faculty led experiments to provide the students with experiential learning in biotechnology.

Curriculum SupportCurriculum Support

Text Biotechnology: Science for the New Millennium, Ellyn

Daugherty Biotech Education Groups (workshops)

County (Gene Connection, SCCBEP etc.) Regional (BABEC) National (Bio-link, BIO etc.)

On the web bio-link.org, accessexcellence.org, biospace.org,

bio.org Consultant

Ellyn Daugherty [email protected]

Text Biotechnology: Science for the New Millennium, Ellyn

Daugherty Biotech Education Groups (workshops)

County (Gene Connection, SCCBEP etc.) Regional (BABEC) National (Bio-link, BIO etc.)

On the web bio-link.org, accessexcellence.org, biospace.org,

bio.org Consultant

Ellyn Daugherty [email protected]

Ellyn DaughertyFounder of the San Mateo

Biotechnology Career Pathway (SMBCP) and recipient of The Biotechnology Institute’s first

National Biotechnology Teacher-Leader Award, has

been teaching from the Biotechnology: Science for the New Millennium in her SMBCP

courses for ten years. Teachers throughout the country have

used her model program to launch Biotechnology programs

in their schools.

Ellyn DaughertyFounder of the San Mateo

Biotechnology Career Pathway (SMBCP) and recipient of The Biotechnology Institute’s first

National Biotechnology Teacher-Leader Award, has

been teaching from the Biotechnology: Science for the New Millennium in her SMBCP

courses for ten years. Teachers throughout the country have

used her model program to launch Biotechnology programs

in their schools.

Financial SupportFinancial Support

School (Dept. Staff Dev., PTA, Boosters, Principal)

District (Grant Writer)State (Specialized Secondary Program -

SSP, SB70)National (NSF, NIH)Industry (Applied Biosystems, Alza, VWR)Private (Peninsula Community

Foundation)

School (Dept. Staff Dev., PTA, Boosters, Principal)

District (Grant Writer)State (Specialized Secondary Program -

SSP, SB70)National (NSF, NIH)Industry (Applied Biosystems, Alza, VWR)Private (Peninsula Community

Foundation)

• Students conduct research and invest $1,000 in a minimum of two Biotechnology companies.

• Weekly, students check progress of stock.

• Students may sell and buy new stock after 60 days.

• Final project is a PowerPoint presentation to the class explaining:

1. Stocks Price Per Share as it changed over time.

2. Stocks Total Value Per Share over time.

3. Reasons for fluctuation in the stocks.

Stock Summaries of Genentech, Gene Logic,

Chiron, and Biogen

Stock Summaries of Genentech, Gene Logic,

Chiron, and Biogen

GenentechGenentechbiotechnology company that discovers, develops, manufactures and commercializes

biotherapeutics for significant unmet medical needs.

13 biotechnology products in the United States.

licenses additional products to other companies

product development efforts cover a range of medical conditions: cancer, respiratory disorders, cardiovascular diseases, endocrine disorders and inflammatory and immune problems.

biotechnology company that discovers, develops, manufactures and commercializes

biotherapeutics for significant unmet medical needs.

13 biotechnology products in the United States.

licenses additional products to other companies

product development efforts cover a range of medical conditions: cancer, respiratory disorders, cardiovascular diseases, endocrine disorders and inflammatory and immune problems.

Gene Logic Continued…Gene Logic Continued…

The Stock value per stock when I first bought 129 shares of Gene Logic was $3.71 and after 18 weeks the stock value per share was $3.45 (Decrease of $.26 per share)

The total price of the stock went from $478.59 to $445.05

The Stock value per stock when I first bought 129 shares of Gene Logic was $3.71 and after 18 weeks the stock value per share was $3.45 (Decrease of $.26 per share)

The total price of the stock went from $478.59 to $445.05

Price Per Share for Genentech and Gene Logic

for 18 Weeks!!!

Price Per Share for Genentech and Gene Logic

for 18 Weeks!!!Price Per Share of Genentech and

Gene Logic for 18 weeks

$0.00$5.00

$10.00$15.00$20.00$25.00$30.00$35.00$40.00$45.00$50.00$55.00$60.00

0 5 10 15 20

Week Number

Price Per Share ($)

Genentech

Gene Logic

Total Value of Stocks for Genentech and Gene Logic for

18 weeks

Total Value of Stocks for Genentech and Gene Logic for

18 weeksTotal Value of Genentech and Gene

Logic per Week for 18 weeks

$300.00

$350.00$400.00

$450.00

$500.00$550.00

$600.00

0 5 10 15 20

Week Number

Total Price ($)

Genentech

Gene Logic

Total Value of Genentech and Gene Logic per Week for 18 weeks

$300.00

$350.00$400.00

$450.00

$500.00$550.00

$600.00

0 5 10 15 20

Week Number

Total Price ($)

Genentech

Gene Logic

•Students use existing scientific knowledge to design an experiment that tests for the presence of protease in unknown samples.

•Formal lab write-up.

•Story board (including camera angles, camera person, narrator, actors, etc.).

•Procedures are filmed in iMovie. Each group of 4 students gets 1 digital camera and 1 iBook.

•Final experiment is presented in PowerPoint with iMovies converted to QuickTime.

You know how protease works. It breaks down proteins. You are going to plan an awesome experiment. With this experiment, you will make millions of dollars.

To protect your money, you need to patent your experiment with the government. However, the government is only accepting experiments that show procedures in movie form.

Objective: (for your group of 4) To design an assay (test) for the presence of protease (protein-digesting enzymes)

Materials: Protease (Adolf’s Meat Tenderizer) and 3 unknown samples. Any other chemicals from the lab or grocery store. Include glassware. You list your own materials in this section.Procedures: You design a valid, controlled experiment to test for protease in unknown samples. Make sure your experiment has:

1. Positive and Negative Controls

2. Multiple replications

3. Everything the same in each trial except the variable being tested.

4. “reasonable” volumes and concentrations

5. MEASURABLE DATA

•Students work in groups of 4 and choose a scientific concept.

•Students must review concepts to be taught and write-out a script (Step-by-Step Procedures).

•Students similarly storyboard project (camera angles, etc.)

•Students turn in a QuickTime movie for peer review.

•Fellow students watch one another’s videos and check for scientific inaccuracies.

•Groups re-film and re-edit to make a final movie.

QuickTime™ and aH.263 decompressor

are needed to see this picture.

• Working solo and acting as a sales and marketing specialist, a student chooses a biotechnology product they are interested in.

• Research is conducted, a letter is sent to the company requesting an annual report, and an expert is encouraged to be found on that specific product (contact company, etc.)

• Students are to become an expert on his/her product and turn in a final PowerPoint presentation to the class.

• Examples are Roundup Ready Soybeans, Nerve Growth Factors, Pulmozyme, ABD #3948 DNA Synthesizer, etc.

THANK YOUTHANK YOU

Any Questions?We are all ears.

Any Questions?We are all ears.

[email protected] [email protected]

Biotechnology In Every School

Education

Transcript of Biotechnology In Every School