Biotechnology and Medicine in Tartu

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Tartu city & county Biotechnology and Medicine in Tartu Sector overview Tartu city World-class research and development Medical and biotechnological hub Applied excellence Knowledge-based Tartu, Estonia

Transcript of Biotechnology and Medicine in Tartu

Tartu city & county

Biotechnology and Medicine in Tartu

Sector overviewTartu city

World-class research and development

Medical and biotechnological hub

Applied excellence

Knowledge-based Tartu, Estonia

Estonia’s medical and biotechnological hubDistinguished history, high-level expertise, world-class research & development.

Tartu is the centre of Estonia’s medical and biotechnological landscape. The University of Tartu Hospital – a unique medical care and training hospital in Estonia – and world-class research & development centres in the field of medicine and biotechnology gathered around the University of Tartu, strong private medical practices as well as biotechnology companies lay the basis for promising future developments.

The life sciences have an outstanding history at the University of Tartu. Medical sciences have been taught here since its foundation in 1632 by the Swedish King Gustav II Adolf. It was at the beginning of the 19th century, however, when medicine here really started to flourish, marked by a number of groundbreaking discoveries valid till the present time. For example Nikolai Pirogov wrote his name in the annals of medical history as the founder of topographic anatomy. Rudolf Buchheim, the founder of the world’s first laboratory of experimental pharmacology, which was situated in Tartu, was also the first to classify drug ingredients according to their chemical effects and pharmacodynamic characteristics, still valid today.

Nowadays the main competences of Estonian biotechnology lie in medical biotechnology, supported by the heritage of the Soviet period as well, when leading groups in the USSR in exact sciences carried out research at the University of Tartu.

These long traditions and internationally recognised research in medicine, biotechnology and chemistry continue in Tartu up to the present day. During the last five years about 300 PhDs and MDs graduated in medicine, biology and chemistry in Tartu. Specialists for the rapidly growing sector are provided by the University of Tartu, Estonian University of Life Sciences and Tartu School of Health Care. More than 750

• www.tartu.ee • www.biotech.ee • www.investinestonia.com • www.eas.ee • www.estonianbiotech.com • www.archimedes.ee • www.geneforum.ee • http://encc.com • www.appliedphenomics.ee • www.asperbio.com • www.bioatlas.com • www.tptak.ee • www.biodata.ee • www.biomedium.ee • www.egeeninc.com • www.fitbiotech.com • www.kinasera.com • www.labas.ee •

“Biotechnology is one of the most

rapidly developing research fields

within the University of Tartu. This

can be said both in respect of

investment numbers and research

results as well as the scale of

international cooperation.

University of Tartu has also

intensive development plans for

the coming years as the new

Centres of Excellences will be

established for R&D in Medical,

Biomedical, Biotechnological

and related fields of research.”

Prof Alar Karis, Rector University of Tartu

Growing workforceProjected employment, biotechnology sectorNumber of employees, 2008 – 2016

Source: (Laidre, 2008), Estonian Biotechnology Strategy 2008-2013

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researchers work at the research and development institutions in the fields of life and exact sciences as well as medicine in Tartu.

The University of Tartu Hospital is the only university hospital and also the largest provider of medical care in Estonia, uniting 17 different profile clinics and employing 3000 people. For several fields (e.g. organ and bone marrow transplantation, paediatric cardiac surgery) it is the only medical treatment provider in Estonia and it also acts as a pioneer in the landscape of medical treatment in Estonia, e.g. the first bone marrow transplantation in Estonia as well as in the Baltics was carried out here in 1993.

But the University of Tartu Hospital is much more than just a regional hospital. As the only university hospital in Estonia, the University of Tartu Hospital plays a substantial role in the lives of undergraduate and postgraduate students, as well as in the development of the country’s medical science. Almost every doctor in Estonia has been educated in Tartu and the majority of medical research and development in Estonia is carried out here as well.

As a university city, the network of private clinics is well-developed in Tartu. Clinics collaborate closely with the research and development institutions as well as with other companies.

• www.tartu.ee • www.biotech.ee • www.investinestonia.com • www.eas.ee • www.estonianbiotech.com • www.archimedes.ee • www.geneforum.ee • http://encc.com • www.appliedphenomics.ee • www.asperbio.com • www.bioatlas.com • www.tptak.ee • www.biodata.ee • www.biomedium.ee • www.egeeninc.com • www.fitbiotech.com • www.kinasera.com • www.labas.ee •

“On December 28, 1895

Wilhelm Conrad Röntgen made

his preliminary report on X-rays.

Two months later, in March 1986

X-rays were already used in Tartu

to image a bullet in the palm of

a young male patient. There is a

unique mixture of world level

historic fame and modern cutting

edge research and medical practice

in this university town.”

Jaanus Pikani, President Estonian Biotechnology Association

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Critical mass is inevitable for carrying out knowledge intensive research. Not just in terms of people, but also in terms of different research objects and topics. For that reason the Centres of Excellence, bringing together high-level research groups in related fields of study, were initiated in 2005. In medical and health sciences two Centres of Excellence – the Centre of Molecular and Clinical Medicine and Estonian Centre of Behavioural and Health Sciences – were founded at the University of Tartu. The Centre of Excellence for Gene and Environmental Technologies set the focus on green biotech. Applied research is encouraged by two Competence Centres, established by a consortium of industrial and science partners – the Bio-Competence Centre of Healthy Dairy Products and Estonian Nanotechnologies Competence Centre.

In addition to these institutions, key actors in biotechnological and medical research in the Tartu region are the Estonian Biocentre, various institutes of the Estonian University of Life Sciences (Institute of Veterinary Medicine and Animal Sciences, Institute of Agricultural and Environmental Sciences) and the University Clinics as well as the University of Tartu (e.g. Institute of Molecular and Cell Biology, Institute of Technology). The Institute of Veterinary Medicine and Animal Sciences is the only research centre in Estonia where studies on animal genetics and reproductive biotechnology, animal health, welfare and veterinary public health are performed.

• www.naxolab.com • www.medfiles.eu • www.pharmasynth.ee • www.quantum.ee • www.quattromed.com • www.cellfactory.quattromed.com • www.quintiles.com • www.quretec.com • www.sbd.ee • www.biodiscovery.eu • www.hot.ee/torrosen • www.alkranel.ee • www.aquaconsult.ee • www.tymri.ut.ee • http://cmcm.ut.ee • www.ebc.ee • www.biotech.ebc.ee • www.emu.ee •

“The University of Tartu Hospital’s

mission is to ensure the continuity

and development of Estonian

medicine through high-level

integrated medical treatment,

training and research.”

Urmas Siigur, Chairman of the Executive Board University of Tartu Hospital

Medical and biotechnological researchAward winning knowledge intensive state-of-the-art research. Locally integrated treatment, training and research. Key players in international R&D networks.

Core competences Main competence fields in biotechnology in Tartu

• Genetics & heredity

• Neurosciences

• Biochemistry

• Bioinformatics

From 2007 the University of Tartu hosts the Estonian Genome Project, the database of the health, genealogy and genome data of the Estonian population. It currently holds data from over 18,000 gene donors, and comprises a valuable collection for both national research on public health as well as international-level research. The aim is to increase the number of gene donors up to 100,000 by 2010.

Research activities of research and development institutes as well as companies in the biotechnological and biomedical field are strongly interlinked with research groups in other European countries. Integration into the European Research Area

and active participation in European Framework Programmes has created a solid basis for the development of life sciences in Estonia. For example, in 2006 the world’s largest charitable biomedicine foundation, Wellcome Trust, awarded an International Senior Research Fellowship grant in the amount of 645,070 GBP to Mart Loog, a senior research fellow at the University of Tartu, in order to promote within five years the research on protein kinase signalling networks in the eukaryotic cell cycle at Loog’s research laboratory. A United States patent was approved in July 17, 2007 for the strain of microorganism Lactobacillus fermentum ME-3 as a novel antimicrobial and antioxidative probiotic discovered by the research group of Marika Mikelsaar from the Institute of Microbiology in cooperation with the Institute of Biochemistry of the University of Tartu. For this discovery and application as a probiotic a “Special Recognition Award” from the European Union Women Inventors & Innovators Network (EUWIIN) was awarded to Marika Mikelsaar in 2007.

• www.naxolab.com • www.medfiles.eu • www.pharmasynth.ee • www.quantum.ee • www.quattromed.com • www.cellfactory.quattromed.com • www.quintiles.com • www.quretec.com • www.sbd.ee • www.biodiscovery.eu • www.hot.ee/torrosen • www.alkranel.ee • www.aquaconsult.ee • www.tymri.ut.ee • http://cmcm.ut.ee • www.ebc.ee • www.biotech.ebc.ee • www.emu.ee •

“We are open to new innovations

and cooperation. In our daily work

state-of-the-art biotechnology

is used, including genetic and

laboratory diagnostics. The Elite

Clinic is the only private maternity

clinic in southern Estonia so far.”

Andrei Sõritsa, Owner and manager Elite

Medical and biotechnological researchAward winning knowledge intensive state-of-the-art research. Locally integrated treatment, training and research. Key players in international R&D networks.

Biotechnology

Biotechnology, added value createdin comparison to other economic sectors in 2006Added value, thousands of Euro per employee

Source: Estonian Biotechnology Strategy 2008-2013

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Estonia has undergone remarkable development from a closed country occupied by the Soviet Union to an active partner in the global economy, prone to adopting new technologies. The liberal economic environment, favourable towards entrepreneurship, has fuelled the growth of the Estonian economy. Biotechnology-related legislation in Estonia is well-established and harmonised with EU legislation. The importance of progress in this sector is also recognised by the government as one of the strategic key technologies. However, today our R&D costs constitute little more than 1% of GDP. The specific goal is to increase gross investment in R&D to 3% of the GDP by 2014.

Millions of euros (5.6 million euros in 2006) have been invested in up-to-date laboratory infrastructure enriching the equipment pool of the Estonian Biocentre and University of Tartu, e.g. core laboratory of sequencing and genotyping (incl. Illumina Beadstation 500GX genotyping platform), core laboratory of biomedicine and molecular and cell biology, transgenic technology core laboratory, core laboratory of applied virology and the core laboratory of proteomics.

Biotechnological entrepreneurship is promoted by several support organisations, such as the Tartu Biotechnology Park and Tartu Science Park. The main objective of the private initiative-based Tartu Biotechnology Park, established in 2001, is to support the development of Estonian high tech and knowledge-based companies in life sciences and medicine and to enhance the international competitiveness of the sector by offering physical infrastructure as well as business development and consultancy services. The Tartu Biotechnology Park supports companies in finding partners and is also active in the establishment process of new companies.

Outstanding potential for growthLiberal economic environment. Effective support organisations. State-of-the-art technologies. Highly qualified experts. International networks.

“Quattromed has acted as a

middleman between science

and business – one of the

cornerstones of our business

strategy has been the process

of transforming knowledge

created in academia to

products and services

needed by society.”

Erki Mölder, CEO Quattromed

• www.tymri.ut.ee • www.tuit.ut.ee • www.geenivaramu.ee • www.genomics.ee • www.biopark.ee • www.teaduspark.ee • www.akliinik.ee • www.clinica.ee • www.eguerapraksis.ee • www.fert-c.ee/elite • www.fert-c.ee/gyne • www.jl.ee • www.medex.ee • www.medicover.com • www.stigma.ee • www.tammeerakliinik.ee • www.kliinikum.ee • www.tipparst.ee • www.fert-c.ee/tahe • www.einst.ee

Exponential sales projectedProjected sales revenue, biotechnology sectorMillions of EUR, 2008 – 2016

Source: (Laidre, 2008), Estonian Biotechnology Strategy 2008-2013

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The Tartu Science Park, supporting business innovation activities in the region by networking with universities, public and private sector, is the oldest science park in Estonia as well as in the Baltics. The Tartu Science Park’s technology incubator offers a variety of services to start-up companies from fully developed infrastructure and office services to business and management consultancy.

The biotechnology sector in the region of Tartu is highly diverse. Considerable expertise can be found in genetics and heredity, neurosciences and biochemistry, which is also reflected in the main activity fields of companies. The majority of companies are active in red biotech focusing on support services for drug development, diagnostics, etc. 24 companies, ca. 50% of Estonian biotech companies, are situated in Tartu. The overall turnover of biotechnology companies, employing over 180 specialists, was about 12 million euros in 2006. The average turnover per company and year is 20,000 – 1,000,000 EUR.

Due to the small size of the internal market products and services are mostly exported. The main export markets are Finland, Sweden, Germany and United

States, but the importance of France and Great Britain is growing as well. International networking is enhanced through participation in the research and development projects supported by the European Commission.

Quattromed, a spin-off from the University of Tartu in 1999, started with offering molecular diagnostics services. Today it is the biggest biotechnology company in Estonia, employing 80 highly skilled professionals. Company’s activities cover clinical and molecular diagnostics (Quattromed HTI Laborid), protein production and biological assays for drug development (Quattromed Cell Factory) and the provision of a large set of research tools in the molecular biology area to life science research institutions worldwide.

Asper Biotech, a genetic testing company founded in 1999, has since grown to become Estonia’s largest biotech exporter. Asper offers diagnostic DNA tests for over fifteen different human diseases to healthcare professionals worldwide. The company also provides custom genotyping projects and genetic testing hardware to the scientific and commercial communities. Asper’s genotyping partners include,

Outstanding potential for growthLiberal economic environment. Effective support organisations. State-of-the-art technologies. Highly qualified experts. International networks.

“Additionally to the traditional

business and development services

a typical technology park offers,

the Tartu Biotechnology Park

as a pathfinder has proactively

taken the initiative to enhance

entrepreneurship in life sciences

and medicine by investing in

new companies.

We are not only taking the shares,

but we also actively participate in

the management of the spin-off

company. The pilot investment,

TBD-Biodiscovery, was made

in 2006.”

Andrus Tasa, CEO Tartu Biotechnology Park

• www.tymri.ut.ee • www.tuit.ut.ee • www.geenivaramu.ee • www.genomics.ee • www.biopark.ee • www.teaduspark.ee • www.akliinik.ee • www.clinica.ee • www.eguerapraksis.ee • www.fert-c.ee/elite • www.fert-c.ee/gyne • www.jl.ee • www.medex.ee • www.medicover.com • www.stigma.ee • www.tammeerakliinik.ee • www.kliinikum.ee • www.tipparst.ee • www.fert-c.ee/tahe • www.einst.ee

amongst others, Columbia University, Stanford University, University College London and several leading global pharmaceutical companies. In May 2008 Asper launched a pan-European direct-to-consumer DNA testing service for members of the public.

The research facility of Finnish company FIT Biotech, an innovative medical biotechnology company engaged in the development of DNA vaccination as well as in immunotherapies and gene therapies, is located in Tartu. The company works closely with the research group of Prof. Mart Ustav from the University of Tartu. Joint research is concentrated on the development of an HIV vaccine that is in its clinical trial phase at the moment. Clinical research organisations in Tartu include EGeen and Quintiles Eesti, which are both branches of international companies headquartered in the US.

Solis BioDyne has been developing and producing life science reagents since 1995, having today become one of the leading reagent suppliers in Europe. Their DNA polymerases, dNTPs, PCR Master Mixes and other reagents are used by a quickly growing number of customers across the globe,

including top research institutes and biotech companies. Solis BioDyne has almost 300 customers, distributors and business partners in 30 countries, the majority of them in Germany (48%), but also in other EU countries, the US (22%) and other countries from Asia and Africa.

TBD Biodiscovery is an innovative contract research company focusing its activities towards synthetic and analytical chemistry. This fast growing spin-off company of the University of Tartu is specialised in the custom-tailored synthesis of molecules for pharmaceutical, agrochemical, chemical and speciality intermediates markets. During the short period of activities TBD Biodiscovery has gained customers from Finnish, Swedish (Biovitrum), UK, French and Estonian biotech and pharmaceutical companies. The process of obtaining a GMP certificate for the company is in force (expected time October 2008).

“High educational standards at the

University of Tartu give a competitive

edge to succeed in the international

market. TBD Biodiscovery penetrated

the foreign market from the first step

of its business and with an aggressive

marketing strategy the company has

achieved tenfold growth in 2007 in

comparison with the year 2006.”

Olga Tshubrik, Head of Development TBD Biodiscovery

• www.tartu.ee • www.biotech.ee • www.investinestonia.com • www.eas.ee • www.estonianbiotech.com • www.archimedes.ee • www.geneforum.ee • http://encc.com • www.appliedphenomics.ee • www.asperbio.com • www.bioatlas.com • www.tptak.ee • www.biodata.ee • www.biomedium.ee • www.egeeninc.com • www.fitbiotech.com • www.kinasera.com • www.labas.ee • www.naxolab.com

• www.tartu.ee • www.biotech.ee • www.investinestonia.com • www.eas.ee • www.estonianbiotech.com • www.archimedes.ee • www.geneforum.ee • http://encc.com • www.appliedphenomics.ee • www.asperbio.com • www.bioatlas.com • www.tptak.ee • www.biodata.ee • www.biomedium.ee • www.egeeninc.com • www.fitbiotech.com • www.kinasera.com • www.labas.ee • www.naxolab.com

A short overview of Estonian biotechnology sectorYear Facts/events

2004 Founded companies and R&D institutions: CeMines Estonia Ltd., GenomicToolbox Ltd., MolCode Ltd., PharmaSynth Ltd., Quretec Ltd. Competence Centre of Food and Fermentation Technologies (R&D institution) Project BioSPINNO2 supported by Enterprise Estonia started.

2005 Establishment of Graduate School in Biomedicine and Biotechnology. Founded companies: Bio-Competence Centre of Healthy Dairy Products (R&D institution), Competence Centre for Cancer Research (R&D institution), FibroTX Ltd., Quattromed Cell Factory OÜ, Quattromed HTI Laborid OÜ New building of the Institute of Technology of University of Tartu. Cornerstone of building for information and biotechnology of Tallinn Park of Technology.

2006 Founded companies and R&D institutions: Bioatlas Ltd., BioMedium Ltd., Kinasera Ltd., TBD BioDiscovery Ltd., Technomedicum of Tallinn University of Technology. Foundation of the Estonian Development Fund.

2007 Founded R&D institution: Centre of Biology of Integrated Systems by Tallinn University of Technology. Estonian Genome Project was integrated with University of Tartu. Estonian parliament approved Estonian Research and Development and Innovation Strategy 2007-2013 “Knowledge-Based Estonia”, where biotechnologies are defined as one of strategic key technologies. Founded companies: BiotaP Ltd.

2008 Estonian Biotechnology Strategy was accepted.

Source: Biotechnology in Estonia: Overview, Companies & Research

Published by Estonian Genome Foundation. Tartu, 2008

Biotechnology and Medical organisations in Tartu

Biotechnology companies

Applied Phenomics LLCLunini 24, 50406 TartuTel: +372 527 3465Clinical [email protected]

Asper Biotech Ltd.Oru 3, 51014 TartuTel: +372 744 1556Molecular diagnostics, [email protected]

Bioatlas Ltd.Riia 181A, 51014 TartuTel: +372 5562 4867Distribution of life-science [email protected]

Bio-Competence Centre of Healthy Dairy ProductsKreutzwaldi 1, 51014 TartuTel: +372 731 3403, +372 516 4210Functional [email protected]

BioData Ltd.Oru 3, 51014 TartuTel: +372 737 [email protected]

BioMedium Ltd.Tiigi 61b, 50410 TartuTel: +372 513 [email protected]

EGeen Inc.Ülikooli 6A, 51003 TartuTel: +372 730 9530Clinical [email protected]

Elementum Ltd.Nooruse 10, 50411 TartuApplied and commercial development of lactic acid and it’s [email protected]

FitBiotech Oyi Plc EstoniaNooruse 9, Tartu 50411Tel: +372 737 7070Medical biotechnology, DNA [email protected]

IasGen Ltd.Pikk 98-58, 50606 TartuTel: +372 740 6164Genome [email protected]

Immunotron Ltd.Riia 185, 51014 TartuTel: +372 5343 [email protected]

Kinasera Ltd.Uus 63-55, 50606 TartuTel: +372 517 5593Inhibitors of protein kinases, fluorescent [email protected]

LabAs Ltd.Kungla 40, 50403 TartuTel: +372 742 8009Mono- and polyclonal antibodies, purified [email protected]

Naxo Ltd.Riia 185, 51014 TartuTel: +372 742 8001Distribution and production of reagents and [email protected]

Medfiles Ltd.Vasara 50, 50113 TartuTel: +372 730 5400Clinical [email protected]

PharmaSynth Ltd.Riia 185, 51014 TartuTel: +372 747 5620PET ligand precursors, PET ligand standards, custom [email protected]

Quantum Eesti Ltd.Saekoja 36a, 50107 TartuTel: +372 730 1321Sale of laboratory and medical [email protected]

Quattromed ASNooruse 9, 50411 TartuTel: +372 737 7070Development and production of research tools in the areas of molecular biology and [email protected]

Quattromed Cell FactoryNooruse 9, 50411 TartuTel: +372 737 7070Stable cell lines, recombinant protein [email protected]

Quintiles Eesti Ltd.Soola 8, 51013 TartuTel: +372 737 1150Co-ordination of clinical [email protected]

Quretec Ltd.Ülikooli 6a, 51003 TartuTel: +372 730 [email protected]

Solis BioDyneRiia 185a, 51014 TartuTel: +372 740 9960Development and production of thermostable DNA [email protected]

TBD BioDiscovery Ltd.Tiigi 61b, 50410 TartuTel: +372 738 3053Chemical [email protected]

Torrosen Ltd.J. Koorti 37, 51011 TartuTel: +372 526 [email protected]/torrosen

Environmental technology

ACESO Envirtech OÜNäituse 22B-26, 50407 TartuTel: +372 501 9455Environmental [email protected]

Alkranel LCCRiia 15b, 51010 TartuTel: +372 736 6676, +372 528 9175Environmental consultation [email protected]

Aqua Consult BalticPikk 14, 51013 TartuTel: +372 744 1249Environmental [email protected]

Research and development

Centre of Excellence for Gene and Environmental TechnologiesRiia 23, 51010 TartuTel: +372 737 5028Research and technological development in molecular and cell biology and gene and environmental [email protected]

Centre of Excellence for Molecular and Clinical MedicineRavila 19, 51014 TartuTel: +372 737 4051Research on brain, mind and [email protected]://cmcm.ut.ee

Estonian BiocentreRiia 23B, 51010 TartuTel: +372 737 5064Research in the field of molecular medicine and [email protected]

EMÜ Estonian University of Life SciencesKreutzwaldi 1, 51014 TartuTel: +372 731 3001The centre of research and development in such fields as food science and environmentally friendly [email protected]

Institute of Molecular and Cell Biology of University of TartuRiia 23, 51010 TartuTel: +372 737 5028Fundamental cancer research, human genetics, complex genetic disease studies and medical [email protected]

Institute of Technology of University of TartuNooruse 1, 50411 TartuTel: +372 737 4800The institute functions as research center and support system for the entire Tartu [email protected]

Estonian Genome Project, University of TartuTiigi 61B, 50410 TartuTel: +372 744 0240Establishment of a database of health, genealogical and genetic data of the people of [email protected]

Support

Estonian Genome FoundationVanemuise 21A, 51014 TartuTel: +372 742 0132Estonian Genome Foundation aims to promote the development of biotechnology in [email protected]

Tartu Biotechnology Park Ltd.Tiigi 61B, 50410 TartuTel: +372 738 3053Tartu Biotechnology Park aims to enhance the development of the life sector, especially biotechnology and medicine in Estonia through providing excellent physical infrastructure, business development and international networking [email protected]

Tartu Science Park FoundationRiia 185, 51014 TartuTel: +372 738 3005The main goal is to provide a variety of services needed in the process of R&D commercialization. Its technology incubator offers a variety of services to start-up companies from fully developed infrastructure and office services to business and management [email protected]

Clinics

A-clinicRiia 13, 51010 TartuTel: +372 742 [email protected]

ClinicaKalevi 110, 50104 TartuTel: +372 734 8553Aesthetic [email protected]

E.G.U.Kivi 25-1, 51009 TartuTel: +372 742 [email protected]

EliteSangla 63, 50407 TartuTel: +372 740 9930Gynaecology, urology, endocrinology, arthroscopy, stomatology, ophthalmology, paediatrics and [email protected]/elite

GyneKalda tee 34, 50707 TartuTel: +372 734 [email protected]/gyne

Jaanson & LääneNäituse 22-23, 50407 TartuTel: +372 782 1011Psychologywww.jl.ee

MedexKalevi 4, 51010 TartuTel: +372 736 6088Day [email protected]

MedicoverTiigi 61B, 50410 TartuTel: +372 731 1958Occupational [email protected]

StigmaPikk 14, 51013 TartuTel: +372 740 [email protected]

TammeKungla 40, 50403 TartuTel: +372 742 8009Gynaecology, urology, endocrinology, cardiology, internal diseases, surgery and medical [email protected]

Tartu University HospitalL. Puusepa 1a, 50406 TartuTel: +372 731 8111Regional hospital, university [email protected]

TipparstVaksali 17, 50410 TartuTel: +372 734 1903Orthopaedics, neurology, [email protected]

TäheTähe 95, 50107 TartuTel: +372 734 8145Gynaecology, andrology, [email protected]/tahe

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Estonian ChambEr of CommErCE and industry tartu offiCE

Lai 6, Tartu 51004, EstoniaTel. +372 744 2196 [email protected] www.koda.ee

tartu sCiEnCE Park

Riia 185, Tartu 51014, EstoniaTel. +372 738 3005 www.teaduspark.ee [email protected]

tartu City GovErnmEnt dEPartmEnt of businEss dEvEloPmEnt

Küüni 5, Tartu 51004, EstoniaTel. +372 736 1196 [email protected] www.tartu.ee

tartu biotEChnoloGy Park

Tiigi 61B, 50410 TartuTel: +372 738 3053 [email protected] www.biopark.ee

Estonian GEnomE foundation

Vanemuise 21A, 51014 TartuTel: +372 742 0132 [email protected] www.genomics.ee

www.tartu.eewww.tartumaa.ee

Ministry of Finance www.fin.ee • Ministry of Foreign Affairs www.wm.ee • http://visitestonia.com • Enterprise Estonia www.eas.ee • Estonian Trade Council www.etc.ee • Baltics Regional Node www.ciesin.ee

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Estonia in brief Area: 45000 km²

Population: 1.34 million Capital: Tallinn (397,000) Other major cities: Tartu (100,000), Narva (68,000), Kohtla-Järve (59,000), Pärnu (45,000) Head of state: President of the Republic – Toomas Hendrik Ilves Official language: Estonian Foreign languages: English, German, Russian, Finnish Main religion: Evangelist Lutheran Government: Parliamentary Republic Single Chamber Parliament of 101 members Currency: 1 Estonian kroon (EEK) =100 sents Exchange rate: EEK 8 = DEM 1, (1992–1998) EEK 15.6466 = Euro 1 (since 1999) Accession to European Union: May 1, 2004 GDP Growth: 7.1% (2007) Local time: GMT +2 hours Average temp. range: -6°C in January and +17°C in July Flight times, Tallinn: Helsinki 35 minutes, Stockholm 1 hour, Copenhagen 1 hour 30 minutes, Moscow 1 hour 40 minutes, Brussels 2 hours 30 minutes, London 2 hours 45 minutes Barcelona 4 hours Distances from Tartu: Tallinn 186km, Narva 184km, Pärnu 178km, Riga 250km, St. Petersburg 315km

Ethnic composition of Tartu: Estonians 80%, Russian 15%, others 5%