Bionanotechnology for Public Security and Environmental ......Bionanotechnology for Public Security...
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Bionanotechnology for Public Security and Environmental Safety West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015 PI: Paul L. Hill, Ph.D. Submied: 16 October 2009 Award Date: 13 August 2010 Official Start Date: 15 August 2010 Expiration Date: 31 July 2015 Award No: EPS-1003907
Transcript of Bionanotechnology for Public Security and Environmental ......Bionanotechnology for Public Security...
Bionanotechnology for Public Security and Environmental Safety
West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
PI: Paul L. Hill, Ph.D.Submitted: 16 October 2009
Award Date: 13 August 2010Official Start Date: 15 August 2010
Expiration Date: 31 July 2015
Award No: EPS-1003907
Bionanotechnology for Public Security and Environmental Safety
Acronyms
BRF Bioengineering Research Facility
CI Cyberinfrastructure
CTC Community and Technical College
ELT Executive Leadership Team
ETAB External Technical Advisory Board
GFP Graduate Fellowship Program
HPC High Performance Computing
IRT Interdisciplinary Research Team
LA Learning Assistants program
MU Marshall University
PUI Predominantly Undergraduate Institution
RCF Research Challenge Fund
SCF Shared Computing Facility
TREK Teacher Research Experience for advancing Knowledge
UREP UnderREPresented Populations
WV West Virginia
WVSU West Virginia State University
WVU West Virginia University
West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
Table of Contents
Executive Summary one
Introduction one
Vision two
Mission two
Alignment with State S&T Priorities two
Strategic Priorities four
Research four
Diversity six
Workforce Developement seven
Cyberinfrastructure seven
External Engagement - Outreach, eight
Communication and Dissemination
Evaluation and Assessment nine
Sustainability ten
Management eleven
Anticipated Impacts of the RII eleven
Appendix A - Milestones twelve
Appendix B - Preliminary Metrics eighteen
Appendix C - Risk Mitigation Matrix tenty-one
Bionanotechnology for Public Security and Environmental Safety
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West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
West Virginia Strategic Plan for RII Implementation
A. Executive Summary
Introduction
Prior investments by NSF and the State of West Virginia in researchers and instrumentation havebuilt a base competency in nanoscience through support of WVNano, the State of West Virginia's initiative for nanoscale science, engineering, education, and workforce and economic development.West Virginia University, Marshall University and West Virginia State University partnered with the WVEPSCoR office and external advisors to develop a program that would build upon prior investments and propel the West Virginia research enterprise forward in bionanotechnology.
In 2010, West Virginia was awarded a $20 million cooperative agreement with the National ScienceFoundation to develop national recognition for strong research and discovery in bionanotechnologyfor public security and environmental safety.
Strategy: The RII program is directed toward a number of complementary activities to enhance
the competitive position of WV S&T to the benefit of its citizens. Specific infrastructure investmentsinclude:
1. Investing in Interdisciplinary Research Teams (IRTs) through new hires and advanced equipment to design and fabricate the critical components for next-generation devices to exploit opportunities in molecular recognition and cell-based platforms. The IRTs will serve as a model for interdisciplinary efforts across multiple WV institutions and we are building a cyber-enabled network of scientists and engineers.
2. Seeding new research opportunities in cellular biology. This research investment is helping leverage established and ongoing state and federal investments in bionanotechnology, thereby providing tools to explore cells and their environment at the nanometer scale. It is also providing a robust opportunity for student training in state-of-the art research experiences.
3. Enhancing student and faculty diversity by implementing a system-wide diversity action plan, the core of which is a WVI3 (Innovation through Institutional Integration) Think Tank which is bringing together key scientists and educators to direct, integrate, and fill gaps in currently funded K-20 programs.
4. Providing workforce training and development opportunities to a diverse group of students and institutions through a new PUI/CTC Incubator, piloting a business-science M.S. program, and engaging the private-sector through internships and entrepreneurial coursework.
5. Enhancing CI by providing researchers with advanced tools to predict nanoscale behavior. Thisactivity is complementing the EPSCoR Track II (RII-T2) award, linking human resources in the state to leverage their intellectual capital.
6. Improving science teacher retention and competency through a pilot program, Teacher Research Experience for advancing Knowledge tied to research activities; recruiting teachers through a Learning Assistants program ; and providing underrepresented minority, disabled persons, first-generation college students and women the tools to be successful in future careers through a new graduate fellowship program.
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Collectively, these initiatives will strengthen the State’s human resource base and provide neededtools to create integrated devices that will advance ongoing biometric identification efforts for publicsecurity, detect environmental toxins, and explore how cells can be used as a platform for more advanced diagnostic devices with private sector engagement.
Previous RII and state investment positioned WV to focus on bionanotechnology as a platform for future R&D. WV’s investment in tools and human resources to build a bionanotechnology platformwill advance 1) next-generation public security research, supporting state leadership in molecularrecognition; 2) field deployable technology to promote environmental stewardship in support ofgreen growth of WV’s energy intensive economy; and 3) nanoscale cell-based devices that can beused to explore cellular responses to the environment. The WVNano Initiative, a State-wide organization enabled by the 2006 RII grant, coordinates the major scientific and educational activities and will be the catalyst for the Center’s creation. The current effort is serving as the foundation for a sustainable, externally funded Center of research excellence in bionanotechnologybenefiting from the State’s established and emerging research and education programs in biometrics,nanotechnology, forensic science, and molecular biology at WVU, MU, and WVSU. Best practices will arise from a careful assessment of the program, and through dissemination will help transform,not only WV, but also other regions of the U.S. to move competitively into the future.
VisionWithin five years, the West Virginia RII program will build a nationally recognized and sustainablestatewide center in Bionanotechnology for Public Security and Environmental Safety.
Mission The West Virginia RII program will build the necessary human and physical research infrastructureand the needed educational and training programs to create a statewide center in Bionanotechnologyfor Public Security and Environmental Safety to advance a biotechnology platform consisting of:
1) Next-generation public security research, supporting state leadership in molecular recognition;
2) Field deployable technology to promote environmental stewardship in support of sustainable growth of WV’s energy intensive economy; and
3) Nanoscale cell-based devices that can be used to explore cellular responses to the environment.
Alignment with State S&T PrioritiesIn FY2005, WVEPSCoR led academic and business leaders in the development of the state’s Science &Technology (S&T) strategic plan, Vision 2015. The plan names identification sciences and bionanotechnology as two key industries for development in WV. Under the bionanotechnologyumbrella, Vision 2015 directs attention to developing public security and environmental safety technologies. The West Virginia RII program addresses these priorities in Vision 2015 and will contribute to the economic development of the state.
The WV RII program provides the necessary infrastructure to stimulate innovative researchand integrated education, workforce development and diversity programs around a platform of bionanotechnology for enhanced public security and environmental safety. Success will enhancethe competitiveness of WV academic institutions and help transform the economy, creating new employment opportunities in the state.
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West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
Overview of Strategic PlanThis RII supports a number of integrated activities to enhance the competitive position of WV Science and Technology. Specific infrastructure investments include: 1) investing in InterdisciplinaryResearch Teams (IRTs) through new hires and advanced equipment to design and fabricate criticalcomponents for next generation devices to exploit opportunities in molecular recognition andcell-based platforms; 2) seeding new research opportunities in cellular biology to leverage establishedand ongoing investments in bionanotechnology, thereby providing tools to explore cells and their environment at the nanometer scale; 3) enhancing student and faculty diversity by implementing a system-wide diversity action plan, the core of which is a WVI3 Think Tank charged with bringingtogether key scientists and educators to direct, integrate, and fill gaps in currently funded K-20 programs; 4) providing workforce training and development opportunities to a diverse group of students and institutions through a new PUI/CTC Incubator, piloting a business-science M.S. program and engaging the private-sector through internships and entrepreneurial coursework; 5) enhancing cyberinfrastructure (CI) by providing researchers with advanced tools to predictnanoscale behavior; 6) improving student retention and science teacher recruitment and competencythrough a pilot program, Teacher Research Experience for Advancing Knowledge (TREK) and aLearning Assistants (LA) program tied to research activities; and 7) providing underrepresented minority, disabled persons, first-generation college students and women the tools to be successful in future careers through a new graduate fellowship program. To enhance research activities andmove toward a Center, regional collaborations are being strengthened with universities and centersof excellence with complementary strengths and needs, such as NIOSH, Carnegie Mellon University,and the NSF-IUCRC, Center for Identification Technology Research, and its affiliates, e.g., DoD theFBI, and various industrial partners.
The WV RII project is congruent with the WV Science and Technology Strategic Plan, Vision 2015. Particularly, the outcomes of this investment in the West Virginia research enterprise will addressseveral of the goals of that plan including building a nationally competitive research cluster, developing intellectual property that will help build tech-based businesses, and increasing STEM student retention (emphasizing broadening participation) and increasing STEM doctorates awarded.
Process
RII participants (including the leadership team and faculty) and members of the WV Science and Research Council met on November 3 and 4, 2010 at the WVU Alumni Center in Morgantown, WV to develop a strategic implementation plan for the WVEPSCoR RII project. Dr. Kevin DiGrigorio facilitated the strategic planning process and NSF Program Officer Dr. Maija Kukla was also presentto observe and provide advice. After review and editing, and approval of the Science and ResearchCouncil, the WV RII Strategic Implementation Plan was provided via email to Dr. Kukla on February2, 2011.
The Strategic Plan which follows is organized in sections that follow the proposal which was submitted by WVEPSCoR: Research (IRT 1, IRT2, IRT2 and Human and Physical Infrastructure), Diversity, Workforce Development, Cyberinfrastructure, External Engagement, Evaluation and Assessment, Sustainability, and Management. For each section, one or two Strategic Priorities weredeveloped. For each Strategic Priority, groups of participants worked together to develop the plansthat would allow them to reach the objective. They also developed a set of provisional metrics (Appendix B) that would allow evaluation of success and milestones (Appendix A) to gauge progress.
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Strategic Priorities
Research:
IRT 1 - PORTABLE AND RAPID IDENTIFICATION PLATFORMS
IRT 1 targets approaches and component technologies that address key barriers to creating rapid,portable DNA analysis needed for biometric applications. To enable rapid and portable microfluidicsystems capable of identifying humans by DNA fingerprinting, IRT1 is developing critical compo-nents: rapid PCR with nanofluidic/microfluidic interface (NMI) concentrators and photonic crystals(PhC) for sensitive and integrated fluorescence detection.
Strategic Priority: Develop rapid and portable microfluidic systems capable of identifying humans and pathogens based on unique DNA signatures while training students and post-docs inthese research areas. Responsible party: IRT1 Leader, Jeremy Dawson
Plans• Integrate modular components for cell lysis, DNA extraction, separation and optical detection
technologies
• Validate bench-top, PCR-based detection and fingerprinting of human and pathogenic DNA
• Develop and optimize microfluidic interfaces
• Refine application-specific rapid, high-resolution electrophoretic DNA separation
• Integrate nanophotonic structures for optical detection of DNA markers into microfluidic architectures
• Collaborate with other regional centers as needed and appropriate
• Educate and train post-docs, PhDs and other students
IRT 2 - FIELD-DEPLOYABLE MICROFLUIDIC ELECTROCHEMICAL SENSORS FOR MULTIPLEXED DETECTION OF HEAVY METALS ANDSMALL MOLECULE TOXINS
The goal of IRT2 is to develop the fundamental scientific knowledge and engineering approaches required to fabricate a highly sensitive, selective, and portable field-deployable microfluidic electrochemical sensor for heavy metals (Hg, Pb and As) and pesticides/herbicides (malathion,atrazine, propanil). This sensor will eventually achieve detection and analysis time comparable or better than commercial large-scale analytical instruments. The IRT’s approach will leverage a sensor element and signal transduction device, developed by Wu and co-workers at WVU that are sensitive and analyte specific.
Strategic Priority: Develop lab-on-a-chip devices for detection of environmental toxins and extend to clinical diagnostic tools while training students and post-docs in these research areas. Responsible Party: IRT2 Leaders Nick Wu and Pete Gannett
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West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
Plans
• Develop aptamer selection methods for environmental toxins
• Optimize molecular recognition probe (aptamer/protein/antibody, binding mechanism of detection)
• Develop and optimize nanoelectrode arrays (NEA) for lab-on-a-chip devices
• Fabricate and optimize microfluidic systems for blood-target separation and analyte capture
• Develop a modular system for on-chip fluids control
• Integrate and test devices
• Develop lab-on-a chip devices (for example, for high-throughput drug screening, cancer marker detection, heavy metal detection)
RESEARCH: IRT 3 - EX VIVO AND IN VITRO BIOMIMETICS FOR CELLULAR RESPONSE MONITORING
The goal of IRT 3 is to develop groundwork for a cell-based sensor platform that seeks to replicate
the complexity of cell behavior in a chip-based component. These cell-based sensors will advance
analytical investigations beyond composition to determine fundamental effects of materials in the
environment. To achieve these goals, microfluidic technology that supports in vitro (from cultured
cells) and ex vivo (from fresh biopsies) culture will be developed and combined with optical
microscopy and downstream integrated nanosensors for analysis of cells that naturally grow in
vivo as monolayers.
Strategic Priority: Develop microfluidic cell-based platforms to assess real time physiological
responses to external agents and stimuli while training students and post-docs in these research
areas. Responsible parties: Yon Rojanasakul at WVU, Elmer Price at MU
Plans
• Design and fabricate microfluidic chips for the growth and study of epithelial or endothelial monolayers
• Develop extracellular matrix (i.e. fibronectin), antibody-coated or surface- derivatized growth areas (MU and WVU)
• Grow cell lines and primary cultures on chips to optimize function and longevity
• Optimize functional assays (NO release for endothelial cells, transepithelial barrier properties, calcium transients or mucus release for epithelial cells)
• Determine the effects of nanoparticles and toxins on monolayer properties
• Integrate chips into instruments for optical and electrical detection and downstream sensors
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HUMAN AND PHYSICAL INFRASTRUCTURE
Strategic Priority: Increase research capability by strategic faculty hiring and investment in advanced instruments. Responsible Parties: John Maher (MU), Curt Peterson (WVU), Ulises Toledo(WVSU)
Plans
• Hire faculty with expertise in organismal development (MU)
• Hire faculty with expertise in molecular mechanisms underlying cellular differentiation (MU)
• Purchase and install advanced genome sequencer (MU)
• Hire faculty with expertise in computational biology (WVSU)
• Purchase and install a suite of shared equipment – HPLC, GC-Mass Spec, protein analyzer, light scanner, microprobe (WVSU)
• Purchase and install 576 cores to expand the Shared Computational Facility (SCF) (WVU)
• Purchase and install suite of shared equipment in BRF (WVU)
Diversity
WVEPSCoR’s diversity plan is initially designed to address student retention issues of
underrepresented populations in the STEM enterprise. As WV is an unusually ethnically
homogenous state (< 5% minority), its underrepresented populations (UREP) include minorities,
women, persons with disabilities, first-generation and/or economically disadvantaged students.
WVEPSCoR has established working relationships with state leaders and key diversity recruitment
and retention programs on partner campuses including CTCs. Through an ongoing team
approach, diversity strategies and initiatives will be conducted, supported and evaluated
throughout the project to ensure use of best practices and that benchmarks and milestones are met.
Strategic Priority: Increase undergraduate UREP student retention rates in STEM degrees
to achieve the same completion rates as majority students. Responsible parties: Brittan Hallar
(WVEPSCoR), Tina Cartwright (MU), Aniketa Shinde (WVU), Dedrielle Taylor (WVSU)
Plans
• Determine and categorize the baseline level of UREP STEM students
• Collect data on barriers, gaps, and best practices for UREP STEM student retention
• Periodically disseminate successful programs throughout the state with state-wide coordination through WVI3 Think Tank and Chancellor’s Diversity Initiative
• Leverage WVI3 and CDI Council to form campus networks and a Statewide network to foster communication and collaboration between campuses, communities, and industry throughout West Virginia
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West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
• Involve PUIs and CTCs in learning about best practices to increase UREP STEM student retention at their respective institutions
• Secure new external funding to implement academic support programs at our institutions that enhance student success and increase UREP STEM student retention
• Involve UREP undergraduate students in science research, targeting IRT projects while not excluding other research projects
• Periodically identify existing institutional support programs (HELP Center, others) and utilize them to enhance student retention as appropriate
• Create a statewide reporting system or assessment tool for UREP students in STEM
Workforce Development
Through this RII, WVEPSCoR is complementing the Governor’s investments in workforcedevelopment (WFD) by focusing on building a diverse workforce in STEM fields, specifically in bionanoscience and biotechnology. WV’s objective is to increase technically competent graduates from the state’s colleges, universities and community colleges.
Strategic Priority: Increase the annual number of STEM graduates from the state’s colleges, universities, and community colleges. Responsible parties: Paul Hill (WVEPSCoR), John Maher (MU, Curt Peterson (WVU) , Ulises Toledo (WVSU)Plans
• Create a “workforce development plan” for STEM fields focusing on nanobio science and biotechnology (HEPC)
• Implement Summer Teacher/Student Research Program (TREK) (MU, WVSU, WVU)
• Continue support of PROMISE and HEG Scholarships (HEPC)
• Create PUI/CTC Incubator Program (MU, WVSU, WVU)
• Design and implement MS/Business degree (MU, WVSU)
• Implement Summer Institutes for HPC (also under CI)
• Implement Graduate Fellowship Program (WVU)
• Implement Learning Assistant (LA) Program (MU, WVSU, WVU)
• Strengthen articulation agreements between CTCs and colleges and universities
Cyberinfrastructure
CI efforts will support both broad CI goals and specific objectives of Vision 2015 which encourages
deployment of sustainable resources and expansion of advanced network infrastructure, enhanced
HPC and data storage resources, acquisition of inter-institutional collaboration tools, and develop-
ment of advanced applications and tools for the research community. Expansion of the Shared
Computational Facility will allow increased computational and modeling integration into RII
research and will establish the path for future growth of CI-enabled research and discovery. It
will also serve as a magnet for future computational research group hires.
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Strategic Priority:: Increase discovery and innovation through computational research and
the collaboration of theoretical, experimental, and computational researchers. Responsible party:
James Lewis
Plans
• Integrate seamlessly with RII Track 2
• Build CI-enabled shared facilities
• Manage a moderately sized HPC cluster to enable computational research
• Sustain resources via increased research competitiveness
• Enable a sustainable CI workforce by offering HPC-related Summer Institutes, system-wide faculty mentoring, and campus-level HPC specific workshops
• Link instrumentation remotely using CI
• Create a virtual science collaboratory
External Engagement - Outreach, Communication and Dissemination
The overall goal of WVEPSCoR’s Outreach, Communication and Dissemination Plan is to effectivelycommunicate results, benefits and processes of science to WV’s citizens at all education levels. Theseefforts will help build scientific literacy in the state and strengthen education and research capacity.
Strategic Priority: Communicate and disseminate the importance, outcomes, and innovations
from the RII and other STEM activities to West Virginia stakeholders, policy makers, and citizens. Responsible party: Kelly Merritt (WVEPSCoR)
Plans
• Continue publication of the Neuron
• Bring in Nanooze-The Exhibition and create ancillary learning activities to extend the experience into the classroom
• Develop a regional edition of the Nanooze magazine
• Advertise in the statewide business magazine, WV Executive
• Continue the biennial statewide STaR Symposium
• Enhance DSR website with a “Discovery” tab highlighting findings of WV researchers
• Create a Press Room on the website to facilitate media access to information
• Contract with MetroNews Radio Networks or other venues for a year-long statewide radio campaign to increase awareness of the benefits of the research in this proposal and others
• Communicate regularly with NSF EPSCoR via telephone, email and/or personal meetings to coordinate NSF involvement in Outreach and Communication activities
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West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
Evaluation and Assessment
Success in the RII program will be measured through a variety of mechanisms all nucleated around
a comprehensive evaluation and assessment plan utilizing qualitative and quantitative approaches to
provide both formative feedback and summative assessment. Process use (self-assessment, collective
knowledge generation and collaborative action) will encompass institutional perspectives and will
create a learning process for the management team that will help build capacity, sustainability and
institutionalization. The management team will be actively engaged in identifying the information
needed to make decisions, and in interpreting and using the evaluative data. The management team
will respond to external evaluation and External Technical Advisory Board (ETAB) and focus on
how recommendations will be incorporated into practice along with a timeframe for the appropriate
actions.
Evaluation findings will be used by the project’s management team to inform processes and
practices, decrease barriers to research competitiveness and develop strength for the formation
of intra/interjurisdiction collaborations to address scientific issues of regional relevance and
national importance.
Strategic Priority: Provide both formative feedback and summative assessment of overall
program implementation, milestones, benchmarks, and deliverables. Responsible party: Rose Shaw
Plans
• Refine and expand the comprehensive evaluation and assessment plan with input from
the grant leadership
• Integrate recommendations of the external evaluation and the External Technical Advisory
Board (ETAB) to inform processes and practices and decrease barriers
• Collect and provide metric data to NSF and stakeholders
• Develop uniform data collection protocols
• Utilize the existing metric collection and reporting system (GO!)
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Sustainability
Infrastructure improvements will be sustained through: 1) human infrastructure and equipment
secured by State [RCF ~$4M annually and RTF] and university funds; 2) continuing efforts to
increase the RCF; 3) increasing number and competitiveness of individual, group and large-scale,
multidisciplinary proposals from all faculty, research clusters and partners; 4) building stronger
research collaborations; 5) setting up university-wide undergraduate research education offices;
and 6) setting up a post-doc and junior faculty mentoring system that will increase success of all
faculty. Cyber-enabled mentoring and continued implementation of Vision 2015 will improve
policies, and financial and infrastructure support for workforce and research enterprise. The BRF
and Cyber Facilities will be sustained as part of the WVNano Shared Facilities. A senior faculty
member will be hired at WVU to be permanent WVNano director, will be sustained by the
university and lead the transition of the program to Center status.
Strategic Priority 1: Sustain and advance the state-wide infrastructure improvements in
bionanotechnology beyond the duration of the RII. Responsible parties: Paul Hill (WVEPSCoR),
John Maher (MU), Curt Peterson (WVU), Ulises Toledo (WVSU)
Plans
• Secure human and physical infrastructure, including equipment, by State (RCF ~$4M annually and RTF) and university funds
• Double the percentage of state video lottery funds dedicated to the RCF
• Increase the number and competitiveness of individual, group and large-scale, multidisciplinary proposals from all faculty, research clusters, and partners
• Promote stronger research collaborations among various institutions
• Set up university-wide undergraduate research education offices
• Set up a post-doc and junior faculty mentoring system that will increase success of all faculty
Strategic Priority 2: Develop additional competitive research areas through seed funding of new
ideas related to the focus of the RII and through developing an emerging area of interdisciplinary
research in cell biology and biotechnology. Responsible parties: Elmer Price (MU), David Lederman
(WVU), Tim Ruhnke (WVSU)
Plans
• Hold annual competition for seed funding
• Develop junior faculty through mentoring and grantsmanship training
• Purchase and install advanced instrumentation at Marshall and West Virginia State Universities
• Develop collaborative research between Marshall and West Virginia State faculty.
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West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
Management
Strategic Priority: Provide leadership oversight and resources and ensure timely completion
of milestones and deliverables through a multi-level management approach. Responsible party:
Paul Hill (WVEPSCoR)
Plans
• Operate a multi-level management team with defined roles and responsibilities
• Conduct quarterly Science and Research Council Meetings to review major areas of project progress
• Conduct quarterly Executive Leadership Team meetings to review budget milestones and deliverables and provide feedback
• Conduct reverse site visit
• Solicit feedback from faculty and staff involved in project and use to evaluate and modify plans and activities
• Conduct annual ETAB program evaluation and use results to modify plans and activities
Plan Revision
This strategic plan will be modified as needed throughout the course of the project, including re-
vising activities, goals, and metrics based on experience and learnings to best fulfill the Vision
and Mission.
We will conduct an Annual Review of the entire Strategic Plan with the full team.
Each team will meet at least quarterly to review and revise plans and will disseminate results,
updates, and changes in Quarterly Reports.
Anticipated Impacts of the RII
This RII will not only advance technology important to national security, but also provide signif-
icant research and education experiences for a diverse group of students, post docs, high school
teachers and institutions in the state. Research discoveries, education and workforce develop-
ment programs will enhance the prosperity of the state and the nation by preparing our citizens
for the increasingly knowledge-based economy. Existing and developing partnerships with
small technology companies, large industry and government agencies such as DoD ensure that
discoveries will be applied beneficially to the problems of the state and nation.
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earc
h i
nit
iate
d
Yea
r 5
1. S
ucc
essf
ul
inte
gra
tio
no
f m
od
ule
s in
to
syst
em-l
evel
ar
chit
ectu
re
2. S
yst
em-l
evel
fu
nct
ion
alit
y a
chie
ved
3. T
ech
tra
nsf
er p
lan
d
evel
op
ed
1.M
od
ula
r sy
stem
of
on
-ch
ip fl
uid
s co
ntr
ol
dev
elo
ped
2. L
ab-o
n-c
hip
dev
ices
dev
elo
ped
an
d
succ
essf
ull
y t
este
d.
1. F
luid
ic c
on
dit
ion
s fo
rlo
ng
-ter
m c
ult
uri
ng
of
cell
s in
ch
ips
op
tim
ized
2. A
pp
roac
hes
fo
r h
igh
-th
rou
gh
pu
t T
EE
R
mea
sure
men
t o
pti
miz
ed(W
VU
)
3. E
ffec
ts o
f n
ano
par
ti-
cles
an
d t
oxi
ns
on
cel
lm
on
ola
yer
s q
uan
tifi
edas
fu
nct
ion
of
toxi
n
con
cen
trat
ion
.
tth
irte
en
So
lici
tati
on
are
aY
ear
1Y
ear
2Y
ear
3Y
ear
4Y
ear
5R
esea
rch
Hu
man
an
d
Ph
ysi
cal
Infr
astr
uct
ure
Div
ersi
ty
1. G
eno
me
seq
uen
cer
inst
alle
d a
nd
o
per
atio
nal
(M
U)
2. C
ell
bio
log
y
inst
rum
enta
tio
n
inst
alle
d a
nd
o
per
atio
nal
(W
VS
U)
1.W
VI3
Th
ink
Tan
k
Ad
vis
ory
Bo
ard
cre
ated
and
act
ive
2. B
asel
ine
dat
a fo
r u
nd
erre
pre
sen
ted
(UR
EP
) S
TE
M
stu
den
ts c
oll
ecte
d
3. D
ata
on
exi
stin
g
cam
pu
s p
rog
ram
s fo
rU
RE
P S
TE
M s
tud
ents
coll
ecte
d.
1. O
rgan
ism
al
dev
elo
pm
ent
facu
lty
hir
ed (
MU
)
2. C
om
pu
tati
on
al
bio
log
y f
acu
lty
hir
ed(W
VS
U)
1.C
amp
us
net
wo
rks
of
UR
EP
ST
EM
pro
gra
ms
crea
ted
an
d c
oo
rdin
ated
2. S
tate
wid
e n
etw
ork
of
cam
pu
ses
and
in
du
stry
crea
ted
an
d a
ctiv
e
3. A
t le
ast
on
e ex
tern
alg
ran
t fu
nd
ed f
or
sup
po
rtin
g U
RE
P
ST
EM
ret
enti
on
4. R
epo
rt o
n U
RE
PS
TE
M s
tud
ents
an
d
pro
gra
ms
com
ple
ted
and
dis
trib
ute
d t
o
inst
itu
tio
ns.
3. C
on
dit
ion
s fo
r N
Oan
d T
EE
R m
easu
rem
ent
for
end
oth
elia
l an
d
epit
hel
ial
cel
ls
op
tim
ized
4. C
ellu
lar
fun
ctio
n
succ
essf
ull
y c
orr
elat
edw
ith
cel
l-sp
ecifi
c b
iom
ark
ers
1. M
ole
cula
r m
ech
anis
ms
facu
lty
hir
ed (
MU
)
2. S
har
ed b
ioen
gin
eer-
ing
res
earc
h f
acil
ity
com
ple
ted
(W
VU
) an
do
per
atio
nal
1. P
rog
ress
of
inst
itu
-ti
on
al c
han
ge
sup
po
rtin
gU
RE
P s
tud
ent
rete
nti
on
trac
ked
.
2. C
om
pre
hen
siv
e d
iver
sity
pla
n
imp
lem
ente
d
4. B
iop
hy
sica
l p
aram
eter
s o
f te
stag
ents
det
erm
ined
5. M
icro
chip
s
succ
essf
ull
y i
nte
gra
ted
wit
h o
pti
cal
and
do
wn
-st
ream
sen
sors
1.S
har
ed
com
pu
tati
on
al
faci
lity
up
gra
de
com
-p
lete
d a
nd
o
per
atio
nal
1. R
eten
tio
n d
ata
for
ST
EM
stu
den
tsth
rou
gh
gra
du
atio
n,
wo
rkfo
rce,
gra
d s
cho
ol
coll
ecte
d a
nd
an
aly
zed
.
2. S
yst
em-w
ide
rep
ort
ing
mec
han
ism
for
ST
EM
UR
EP
st
ud
ents
an
d
pro
gra
ms
dev
elo
ped
and
im
ple
men
ted
su
cces
sfu
lly
fou
rtee
n
So
lici
tati
on
are
aY
ear
1Y
ear
2Y
ear
3Y
ear
4Y
ear
5R
esea
rch
Div
ersi
ty C
on
t.
Wo
rkfo
rce
Dev
elo
pm
ent
1. W
ork
forc
e D
evel
op
men
t C
om
mitt
ee
dev
elo
ped
an
d c
on
ven
ed
2. R
FP
fo
r P
UI
incu
bat
or
rele
ased
3. P
UI
Incu
bat
or
Gra
nt
awar
ded
4. M
S/b
usi
nes
s em
ph
asis
deg
ree
pro
gra
m d
esig
ned
5. C
amp
us
Ed
uca
tio
n
Co
ord
inat
ors
hir
ed
6. T
hre
e n
ew c
ou
rses
d
evel
op
ed a
nd
sc
hed
ule
d f
or
TR
EK
teac
her
s
7. T
each
ers
and
stu
den
ts
succ
essf
ull
y r
ecru
ited
for
TR
EK
8. R
esea
rch
pla
ns
dev
elo
ped
an
d
imp
lem
ente
d f
or
TR
EK
tea
cher
s
5. C
om
pre
hen
siv
e d
iver
sity
pla
n d
evel
op
ed
6. T
hin
k T
ank
re
com
men
dat
ion
s o
nsu
pp
ort
ing
an
d i
mp
rov
-in
g U
RE
P S
TE
M s
tud
ent
rete
nti
on
an
d p
rog
ram
sp
rov
ided
to
in
stit
uti
on
s
1. S
TE
M w
ork
forc
e d
evel
op
men
t p
lan
d
evel
op
ed
2. P
UI
Incu
bat
or
Gra
nts
awar
ded
3. M
S/b
usi
nes
s em
ph
asis
deg
ree
pro
gra
m
imp
lem
ente
d
4. T
each
ers
and
stu
den
tssu
cces
sfu
lly
rec
ruit
ed
for
TR
EK
5. T
RE
K im
ple
men
ted
6. L
A p
arti
cip
ants
an
dfa
cult
y s
ucc
essf
ull
y
recr
uit
ed a
nd
tra
ined
7. L
A p
rog
ram
Im
ple
men
ted
8. G
rad
uat
e F
ello
ws
recr
uit
ed a
nd
fel
low
ship
saw
ard
ed
1. P
UI
Incu
bat
or
Gra
nts
awar
ded
2. T
each
ers
and
stu
den
ts
succ
essf
ull
y r
ecru
ited
for
TR
EK
3. T
RE
K
imp
lem
ente
d
4. L
A p
arti
cip
ants
an
dfa
cult
y s
ucc
essf
ull
y
recr
uit
ed a
nd
tra
ined
5. L
A p
rog
ram
im
ple
men
ted
6. G
rad
uat
e F
ello
ws
recr
uit
ed a
nd
fel
low
-sh
ips
awar
ded
1. P
UI
Incu
bat
or
Gra
nt
awar
ded
2. T
each
ers
and
st
ud
ents
su
cces
sfu
lly
re
cru
ited
fo
r T
RE
K
3. L
A p
arti
cip
ants
an
dfa
cult
y s
ucc
essf
ull
y
recr
uit
ed a
nd
tra
ined
4. L
A p
rog
ram
im
ple
men
ted
5. G
rad
uat
e F
ello
ws
recr
uit
ed a
nd
fel
low
-sh
ips
awar
ded
1. T
each
ers
and
st
ud
ents
su
cces
sfu
lly
re
cru
ited
fo
r T
RE
K
2. T
RE
K i
mp
lem
ente
d
3. L
A p
arti
cip
ants
an
dfa
cult
y s
ucc
essf
ull
y
recr
uit
ed a
nd
tra
ined
4. L
A p
rog
ram
im
ple
men
ted
fift
een
So
lici
tati
on
are
aY
ear
1Y
ear
2Y
ear
3Y
ear
4Y
ear
5R
esea
rch
Wo
rkfo
rce
Dev
elo
pm
ent
Co
nt.
Cy
ber
-in
fras
tru
ctu
re
9. A
pp
rov
al o
f ed
uca
tio
np
lan
s b
y c
amp
us
IRB
s
10. B
asel
ine
dat
a co
llec
ted
fo
r T
RE
K a
nd
LA
pro
gra
ms
11. P
edag
og
y c
ou
rse
dev
elo
ped
fo
r L
A
par
tici
pan
ts
12. L
A p
arti
cip
ants
an
dfa
cult
y s
ucc
essf
ull
y
recr
uit
ed a
nd
tra
ined
13. G
rad
uat
e F
ello
ws
recr
uit
ed a
nd
fel
low
-sh
ips
awar
ded
1. S
um
mer
In
stit
ute
fo
r H
PC
dev
elo
ped
2. F
irst
128
no
des
fo
rS
har
e C
om
pu
tin
g
Fac
ilit
y (
SC
F)
inst
alle
d
1. S
um
mer
In
stit
ute
fo
rH
PC
hel
d
2. N
ext
128
no
des
(fu
nd
ed b
y R
II T
rack
2)
inst
alle
d
3. C
amp
us
rese
arch
-sp
ecifi
c H
PC
wo
rksh
op
sh
eld
4. S
uit
able
in
stru
men
ta-
tio
n r
emo
tely
lin
ked
v
ia C
I
5. V
irtu
al S
cien
ce
Co
llab
ora
tory
cre
ated
and
in
use
1. S
um
mer
In
stit
ute
fo
r H
PC
hel
d
2. N
ext
64
no
des
in
stal
led
3. C
amp
us
rese
arch
-sp
ecifi
c H
PC
wo
rksh
op
sh
eld
1. S
um
mer
In
stit
ute
fo
r H
PC
hel
d
2. N
ext
128
no
des
in
stal
led
3. C
amp
us
rese
arch
-sp
ecifi
c H
PC
wo
rk-
sho
ps
hel
d
1. S
um
mer
In
stit
ute
fo
r H
PC
hel
d
2. F
inal
192
no
des
in
stal
led
3. C
amp
us
rese
arch
-sp
ecifi
c H
PC
wo
rk-
sho
ps
hel
d
sixt
een
So
lici
tati
on
are
aY
ear
1Y
ear
2Y
ear
3Y
ear
4Y
ear
5R
esea
rch
Ext
ern
al
En
gag
emen
t
Ev
alu
atio
n a
nd
A
sses
smen
t
Su
stai
nab
ilit
y
1. T
he
Neu
ron
p
ub
lish
ed q
uar
terl
y
2. R
II A
ds
pu
bli
shed
in
WV
Exe
cuti
ve
mag
azin
e
3. S
TaR
Sy
mp
osi
um
hel
d
4. P
ress
Ro
om
cr
eate
d o
n D
SR
web
site
1. C
om
pre
hen
siv
e ev
alu
atio
n p
lan
refi
ned
and
exp
and
ed
2. R
eco
mm
end
atio
ns
pro
vid
ed t
o l
ead
ersh
ipan
d e
xter
nal
ad
vis
ors
3. U
nif
orm
dat
a co
llec
tio
n p
roto
cols
d
evel
op
ed
4. E
val
uat
ion
dat
a co
llec
ted
1. P
ost
-do
c m
ento
rin
gp
rog
ram
est
abli
shed
2. I
nte
r-u
niv
ersi
ty
coll
abo
rati
on
s es
tab
lish
ed
3. G
ran
tsm
ansh
ip
trai
nin
g i
mp
lem
ente
d
1. T
he
Neu
ron
p
ub
lish
ed q
uar
terl
y
2. D
isco
ver
y t
ab h
igh
-li
gh
tin
g W
V r
esea
rch
crea
ted
on
DS
R w
ebsi
te
3. S
tate
wid
e ra
dio
ca
mp
aig
n w
ith
RII
re
sear
ch s
po
ts
imp
lem
ente
d
1. R
eco
mm
end
atio
ns
pro
vid
ed t
o l
ead
ersh
ipan
d e
xter
nal
ad
vis
ors
2. E
val
uat
ion
dat
a co
llec
ted
1. S
tate
lo
tter
y f
un
ds
ded
icat
ed t
o t
he
Res
earc
h C
hal
len
ge
Fu
nd
do
ub
led
2. U
niv
ersi
ty-w
ide
un
der
gra
du
ate
rese
arch
offi
ces
esta
bli
shed
3. J
un
ior
facu
lty
m
ento
rin
g p
rog
ram
im
ple
men
ted
1. T
he
Neu
ron
p
ub
lish
ed q
uar
terl
y
2. N
ano
oze
-Th
e E
xhib
itio
n b
rou
gh
t in
to
to
ur
WV
sch
oo
ls
3. R
egio
nal
Nan
oo
zem
agaz
ine
crea
ted
an
dd
istr
ibu
ted
4. S
TaR
Sy
mp
osi
um
hel
d
1. R
eco
mm
end
atio
ns
pro
vid
ed t
o l
ead
ersh
ipan
d e
xter
nal
ad
vis
ors
2. E
val
uat
ion
dat
a co
llec
ted
1. I
nte
r-u
niv
ersi
ty
coll
abo
rati
ve
pro
po
sals
sub
mitt
ed
1. T
he
Neu
ron
p
ub
lish
ed q
uar
terl
y
2. R
egio
nal
Nan
oo
zem
agaz
ine
pu
bli
shed
an
d d
istr
ibu
ted
1. R
eco
mm
end
atio
ns
pro
vid
ed t
o l
ead
ersh
ipan
d e
xter
nal
ad
vis
ors
2. E
val
uat
ion
dat
a co
llec
ted
1. I
nte
r-u
niv
ersi
ty
coll
abo
rati
ve
pro
po
sals
sub
mitt
ed
2. I
nte
r-u
niv
ersi
ty
coll
abo
rati
ve
pro
po
sals
sub
mitt
ed
1. T
he
Neu
ron
pu
bli
shed
qu
arte
rly
2. R
egio
nal
Nan
oo
zem
agaz
ine
pu
bli
shed
an
d d
istr
ibu
ted
3. S
TaR
Sy
mp
osi
um
hel
d
1. R
eco
mm
end
atio
ns
pro
vid
ed t
o l
ead
ersh
ipan
d e
xter
nal
ad
vis
ors
2. E
val
uat
ion
dat
a co
llec
ted
1. I
nte
r-u
niv
ersi
ty
pro
po
sals
fu
nd
ed
2. I
nte
r-u
niv
ersi
ty
coll
abo
rati
ve
pro
po
sals
su
bm
itted
sev
ente
en
So
lici
tati
on
are
aY
ear
1Y
ear
2Y
ear
3Y
ear
4Y
ear
5R
esea
rch
Man
agem
ent
1.Q
uar
terl
y S
cien
ce
and
Res
earc
h C
ou
nci
l m
eeti
ng
s h
eld
2. Q
uar
terl
y E
LT
m
eeti
ng
s h
eld
3. E
val
uat
or’
s re
com
men
dat
ion
s im
ple
men
ted
4. Q
uar
terl
y c
amp
us
vis
its
con
du
cted
1.Q
uar
terl
y S
cien
ce a
nd
Res
earc
h
Co
un
cil
mee
tin
gs
hel
d
2. Q
uar
terl
y E
LT
m
eeti
ng
s h
eld
3. R
ever
se s
ite
vis
it
succ
essf
ull
y c
on
clu
ded
4. E
TA
B p
rog
ram
ev
alu
atio
n h
eld
5. E
TA
B
reco
mm
end
atio
ns
imp
lem
ente
d
6. E
val
uat
or’
s re
com
men
dat
ion
s im
ple
men
ted
7. Q
uar
terl
y c
amp
us
vis
its
con
du
cted
1.Q
uar
terl
y S
cien
ce
and
Res
earc
h C
ou
nci
l m
eeti
ng
s h
eld
2. Q
uar
terl
y E
LT
m
eeti
ng
s h
eld
3. E
TA
B p
rog
ram
ev
alu
atio
n h
eld
4. E
TA
B r
eco
mm
end
a-ti
on
s im
ple
men
ted
5. E
val
uat
or’
s re
com
men
dat
ion
s im
ple
men
ted
6. Q
uar
terl
y c
amp
us
vis
its
con
du
cted
1.Q
uar
terl
y S
cien
cean
d R
esea
rch
Co
un
cil
mee
tin
gs
hel
d
2. Q
uar
terl
y E
LT
m
eeti
ng
s h
eld
3. R
ever
se s
ite
vis
it
succ
essf
ull
y c
on
clu
ded
4. E
TA
B p
rog
ram
ev
alu
atio
n h
eld
5. E
TA
B
reco
mm
end
atio
ns
imp
lem
ente
d
6. E
val
uat
or’
s re
com
men
dat
ion
s im
ple
men
ted
7. Q
uar
terl
y c
amp
us
vis
its
con
du
cted
1.Q
uar
terl
y S
cien
ce
and
Res
earc
h C
ou
nci
lm
eeti
ng
s h
eld
2. Q
uar
terl
y E
LT
m
eeti
ng
s h
eld
3. E
TA
B p
rog
ram
ev
alu
atio
n h
eld
4. E
TA
B r
eco
mm
end
a-ti
on
s im
ple
men
ted
5. E
val
uat
or’
s re
com
men
dat
ion
s im
ple
men
ted
6. Q
uar
terl
y c
amp
us
vis
its
con
du
cted
Bionanotechnology for Public Security and Environmental Safety
Research
All iRTs and
Sustainability priority 2
Human and physical infrastructure
Diversity
Workforce Development
number of peer-reviewed research publications
number of citations in nationally recognized
peer reviewed research publications
number of invited talks
employment of program graduates in academic,
industrial, and government organizations
number and dollar value of extramural
research grants awarded
number of scientific outreach and education
grants awarded
number of undergraduate degrees awarded
number of phds awarded
number of post-docs trained
number of undergraduates matriculating to
graduate school
number of invention disclosures
number of patents
Successful faculty hiring when planned
Timely installation of equipment
Graduation rates for URep students in STeM
URep students participating in LA program
Completion rates of URep students receiving a
C or better in LA-supported courses
Grant submitted to support URep STeM
student retention
number of participating pUis and CTCs
participating in statewide URep STeM student
retention initiatives
number of URep undergraduate students in
iRT project research
A statewide reporting system or assessment tool
for URep students in STeM
number of new courses developed
(TReK, LA, GFp)
5
TBd, citations
will appear Yr 2
8
TBd, data
collected Sept. '11
$2.90M (18)
$1.17M (1)
21
13
2
TBd, data
collected Sept. '11
3
2
faculty hires
completed Yr 2&3
Fall 2009
enrollment: 847
Fall 2011 data
Fall 2011 data
1
TBd Year 2
1
0
0
10
doubled
15
+50%
$5.80M (36)
2.3M (2)
30
16
8
+25%
+50%
3
new hires
retained
equipmentinstalled in
Yrs 1-3
At thesame rateas theirmajoritycounter-
parts
50% of LAs
90%
2
TBd
5
developedand in use
4
WVEPSCoR RII Metrics (baseline is year one of the grant due to mismatch with faculty and projects in last grant)
Strategic Priority Area Provisional Metrics Baseline 5-Yr Target
eight-
teen
A p p e n d i x B
nine-teen
West Virginia EPSCoR Strategic Plan for RII Implementation 2010-2015
Strategic Priority Area Provisional Metrics Baseline 5-Yr Target
Degree program developed (MS/Business)
Number of persons completing TREK
Number of persons completing LA Program
Number of persons completing MS/Business
degree
Number of Graduate Fellows completing PhD
Workforce Development Plan created
Number of PUIs receiving PUI Incubator awards
Number of proposals resulting from Incubator
grants
Number of awards resulting from Incubator
grants
Number of publications resulting from
Incubator grants
Number of graduate fellows mentored
Employment/collaboration of program graduates at academic, industry and government organizations (GFP, MS/Business)
Number of Internships established
(MS/Business)
Increase in the overall number of
computational community members
Increase in the number of interdisciplinary
computational/experimental grants
Increase in the number of interdisciplinary
computational/experimental publications
Amount of hardware resources obtained
beyond those provided by the RII
Increase in number of computational (only)
grants
Increase in number of computational (only)
publications
Number of students participating in Nanooze
exhibits
Number of classrooms and students using
ancillary learning activities
Number of WV Executive readers
Number of participants in STaR Symposium
Listenership of WV MetroNews Radio Network
Workforce DevelopmentCont..
Participation by UREP(TREK, LA, GFP,MS/Business)
Cyberinfrastructure
External Engagement
0
30
22
0
0
0
1
0
0
0
6
0
TBD, begins Yr 2
6
3
3
0
3
4
0
0
90,000
135
TBD, begins Yr 2
2
120
176
10/yr.
total 24 by yr 5
1
total 4, by yr 5
8 by yr 5
total 3 by yr 5
5 by year 5
total 30, byYr 5
75%
10
50
10
10
100%
15
20
500
20/500
100,000
200
100,000
Bionanotechnology for Public Security and Environmental Safety
twenty
Strategic Priority Area Provisional Metrics Baseline 5-Yr Target
External Engagement
Cont.
Evaluation and
Assessment
Sustainability
Strategic Priority 1
Management
Number of unique and repeat visitors to DSR website, particularly to Discovery and Press Room
Number of print and other media pieces on RII
activities
External evaluator reports
On-site review summaries (ETAB reports)
Timely submission of program reports
Plans and activities modified in response to
evaluations
Number of WV Nano shared facilities users, including internal and external users and thosefrom academic, industrial, and government organizations
Number of external users of shared facilities
Number of academic users
Number of industrial users
Number of government users
Number of proposals that include user fees for
the shared facilities
Number of collaborative and interdisciplinary
proposals submitted
Number and dollar value of awards obtained
Percentage of video lottery funds dedicated to RCF
Dollars per year available from RCF
Creation of undergraduate research offices on all
three campuses
Number and type of IP actions and
commercialization
Budget expenditures on schedule and accurate
Deliverables reported on schedule
Reverse site visit successful
ETAB program evaluations provided in writing
and used by management and research teams
Unique IPs20,639 Total
Visitors 54,366total visitors tonew tabs 9,113
16
97
5
94 (2 external)
2
1
11
5
$4.1M (19)
0.50%
$3.1M
yes
2
quarterly
yes
+25%
24 in Yr 5
annually
annually
annually
annually
120
10
115
3
2all that makeuse of shared
facilities
10 annually
8.2M (38)
double
$6.2M
sustained
3 licenses/start-ups
annually
all successful
annually
Co
mp
on
ent
Co
nd
itio
nC
on
seq
uen
ceIm
pac
tL
ikel
iho
od
Mit
igat
ion
Res
earc
h –
Gen
eral
IRT
1:
Tra
vel
ing
Wav
e E
letr
o-
ph
ore
sis
(TW
E)
IRT
1:
Th
erm
ally
re
ver
sib
leth
erm
o-g
el
IRT
1:
Ph
oto
nic
cry
stal
-bas
ed
flu
ore
scen
ceen
han
cem
ent
IRT
man
agem
ent
do
esn
ot
faci
lita
te t
ruly
in
terd
isci
pli
nar
y w
ork
.
TW
E i
s n
ot
cap
able
of
per
form
ing
hig
h r
eso
lu-
tio
n D
NA
sep
arat
ion
s
Mu
lti-
lay
er T
WE
ar
chit
ectu
re i
s n
ot
stru
c-tu
rall
y r
elia
ble
Po
lym
er g
el e
xhib
its
larg
e p
erfo
rman
ce
dis
crep
ancy
dep
end
ent
on
bas
e-p
air-
size
ran
ge
of
inp
ut
sam
ple
Ch
ann
el m
ater
ials
no
tco
mp
atib
le w
ith
oth
ersy
stem
co
mp
on
ent
arch
itec
ture
s
En
han
cem
ent
in l
attic
ed
efec
ts n
ot
exp
erim
en-
tall
y m
easu
reab
le
Res
earc
h g
oal
s ar
e n
ot
met
,p
utt
ing
us
in a
les
s co
mp
eti-
tiv
e p
osi
tio
n f
or
adv
anci
ng
re
sear
ch a
nd
res
earc
h f
un
din
g.
Alt
ho
ug
h t
he
rese
arch
may
be
val
id, i
t w
ou
ld n
ot
be
rese
arch
that
rea
lly
req
uir
es a
gro
up
in
terd
isci
pli
nar
y e
nv
iro
nm
ent
to s
up
po
rt.
DN
A s
enso
r w
ou
ld b
e m
issi
ng
cen
tral
fu
nct
ion
alit
y
Sy
stem
pro
ne
to l
eak
age
and
incr
ease
d l
ikel
iho
od
of
fail
ure
Ov
eral
l se
par
atio
n r
eso
luti
on
dep
end
ent
on
sam
ple
ty
pe
(hu
man
ST
Rs
vs.
pat
ho
gen
)
Incr
ease
d s
yst
em c
om
ple
xity
Co
nse
qu
ence
No
im
pro
vem
ent
in l
imit
of
det
ecti
on
an
d a
sso
ciat
ed
nu
mb
er o
f P
CR
cy
cles
nee
ded
Med
ium
Hig
h
Med
ium
Med
ium
Lo
w
Hig
h
Hig
h
Hig
h
Med
ium
Lo
w
Med
ium
Med
ium
Pro
gra
m m
anag
emen
t h
as i
ncr
ease
d
men
tori
ng
of
IRT
lea
der
s to
im
pro
ve
com
mu
nic
atio
n a
nd
co
llab
ora
tio
n; h
ow
-ev
er, u
np
rod
uct
ive
and
/or
dy
sfu
nct
ion
alIR
Ts
wil
l re
qu
ire
rep
lace
men
t o
f IR
T
lead
ersh
ip o
r te
rmin
atio
n o
f th
e IR
T.
See
d p
roje
cts
hav
e b
een
str
ateg
ical
ly
sele
cted
to
pro
vid
e al
tern
ativ
e re
sear
char
eas
in c
ase
this
hap
pen
s.
Use
TW
E f
or
con
cen
trat
ion
an
d
pu
rifi
cati
on
; Use
th
erm
ally
rev
ersi
ble
ther
mo
-gel
as
sole
sep
arat
ion
co
mp
on
ent
Dev
elo
p s
ing
le-e
lect
rod
e la
yer
arc
hit
ectu
re
Per
form
fu
nct
ion
al t
esti
ng
to
op
tim
ize
reso
luti
on
fo
r w
ide
ran
ge
of
sam
ple
ty
pes
Ev
alu
ate
fun
ctio
nal
ity
in
a v
arie
ty o
f m
ater
ial
syst
em;
Dev
elo
p h
yb
rid
sy
stem
wit
h s
imp
le f
abri
cati
on
an
d h
igh
rel
iab
ilit
y
Uti
lize
latt
ice
surf
ace
as m
ain
en
han
cem
ent
mec
han
ism
AP
PE
ND
Ix
C.
WV
EP
SC
OR
RI
I R
IS
K M
IT
IG
AT
IO
N A
NA
LY
SI
S M
AT
RI
x
twen
ty-o
ne
twen
ty-t
wo
Ref
ract
ive
ind
ex o
f m
ater
ials
use
d f
or
oth
ersy
stem
co
mp
on
ents
do
es n
ot
crea
te i
nd
exco
ntr
ast
suffi
cien
t to
set
up
op
tica
l b
and
gap
nec
-es
sary
fo
r en
han
cem
ent
Th
e ac
tual
rea
liza
tio
n o
fth
e co
mp
ute
r-d
esig
ned
apta
mer
do
es n
ot
bin
das
pre
dic
ted
by
th
e co
mp
ute
r d
esig
n.
To
mak
e d
ot
size
smal
ler
and
dis
tan
cela
rger
req
uir
es e
tch
ing
larg
e sp
her
es i
n t
he
tem
-p
late
use
d f
or
nan
oel
ec-
tro
de
arra
y f
abri
cati
on
;h
ow
ever
, th
e sp
her
esco
uld
be
mel
ted
du
rin
get
chin
g.
Diffi
cult
y g
row
ing
thre
e-d
imen
sio
nal
cel
lst
ruct
ure
s w
ith
in t
he
mic
rofl
uid
ic c
han
nel
s
Fu
nct
ion
alit
y o
f m
old
ed l
attic
est
ruct
ure
s co
mp
rom
ised
Dec
reas
e in
sen
sor
spec
ifici
tym
ay r
end
er s
enso
r le
ss
com
pet
itiv
e w
ith
alt
ern
ativ
ete
chn
olo
gie
s.
On
ce s
ph
eres
are
mel
ted
d
uri
ng
etc
hin
g, d
esir
ed d
ot
size
an
d i
nte
r-d
ot
spac
ing
ca
nn
ot
be
ob
tain
ed, a
nd
do
tsh
ape
may
be
deg
rad
ed.
On
lyN
EA
s w
ith
lar
ge
size
an
dsm
all
dis
tan
ce c
an b
e fa
bri
-ca
ted
. S
ensi
tiv
ity
of
the
sen
sor
wil
l b
e d
imin
ish
ed.
Th
e se
nso
r ca
nn
ot
be
fab
rica
ted
wit
ho
ut
the
thre
e-d
imen
sio
nal
cel
l st
ruct
ure
s
Hig
h
Med
ium
Hig
h
Hig
h
Ev
alu
ate
mo
ldin
g p
roce
ss i
n w
ide
ran
ge
of
mic
rofl
uid
ic m
ater
ials
to
det
erm
ine
tho
se b
est
for
ban
dg
ap c
reat
ion
an
d s
yst
emin
teg
rati
on
NM
R m
easu
rem
ents
wil
l b
e u
sed
to
u
nd
erst
and
th
e n
atu
re o
f fa
ilu
re t
o b
ind
.B
ecau
se t
her
e ar
e m
any
ap
tam
er
con
form
atio
ns
that
diff
er v
ery
sli
gh
tly
,sm
all
chan
ges
in
str
uct
ure
co
uld
res
olv
e th
e p
rob
lem
. T
ho
ug
h l
ess
no
vel
, SE
LE
x
is a
hig
h-p
rob
abil
ity
-of-
succ
ess
alte
rnat
ive.
a. R
edu
ce t
he
po
wer
of
pla
sma
etch
ing
to
low
er t
he
etch
ing
rat
e;
b.
Do
no
t p
erfo
rm c
on
tin
uo
us
etch
ing
. In
stea
d, e
tch
fo
r a
sho
rt p
erio
d o
f ti
me
and
th
en c
oo
l fo
r a
per
iod
of
tim
e.c.
Dev
elo
p a
new
etc
han
t re
cip
e.M
itig
atio
n
Alt
ho
ug
h w
ays
of
dev
elo
pin
g t
he
cell
ula
rst
ruct
ure
s h
ave
bee
n d
evel
op
ed, t
hey
are
tim
e co
nsu
min
g a
nd
th
e ep
ith
elia
l ce
ll
lay
ers
pro
du
ced
are
no
t al
way
s as
co
nti
nu
ou
s as
req
uir
ed f
or
the
sen
sor
to w
ork
. If
we
can
no
t d
ecre
ase
the
tim
ean
d i
ncr
ease
th
e co
her
ence
, we
wil
l in
ves
tig
ate
bri
ng
ing
in
a v
isit
ing
res
earc
hw
ith
exp
erti
se i
n t
his
are
a to
ass
ist
us
in
dev
elo
pin
g a
n a
lter
nat
ive
pro
ced
ure
.
Med
ium
Med
ium
Hig
h
Med
ium
IRT
2:
Ap
tam
er
sele
ctio
n
IRT
2: N
ano
-el
ectr
od
eA
rray
IRT
3:
Cel
lula
r S
enso
rsC
om
po
nen
t
IRT
3:
Cel
lula
r S
enso
rs(W
VU
)
Co
mp
on
ent
Co
nd
itio
nC
on
seq
uen
ceIm
pac
tL
ikel
iho
od
Mit
igat
ion
twen
ty-t
hre
e
Lac
k o
f n
ov
elty
or
bre
adth
of
det
ecti
on
En
do
thel
ial
cell
s d
o n
ot
surv
ive
for
a su
ffici
ent
tim
e fr
ame
En
do
thel
ial
cell
s w
ill
no
tre
spo
nd
to
qu
ery
su
b-
stan
ce
En
do
thel
ial
cell
s la
cksu
ffici
ent
sen
siti
vit
y
A d
rop
in
res
ista
nce
up
on
cel
l ex
po
sure
to
sin
gle
wal
led
car
bo
nn
ano
tub
es c
an b
e att
rib
-u
ted
to
bo
th c
han
ges
in
cell
mo
rph
olo
gy
as
wel
las
cel
l d
eath
.
Wil
l m
ake
it d
ifficu
lt t
o f
un
dp
roje
ct a
nd
les
s u
sefu
l to
p
ote
nti
al c
on
sum
ers
Dev
ice
wil
l n
ot
hav
e an
ad
equ
ate
“sh
elf
life
”
Dev
ice
wil
l n
ot
det
ect
un
kn
ow
ns
Dev
ice
wil
l n
ot
be
sup
erio
r to
exis
tin
g m
eth
od
s
Har
d t
o d
isti
ng
uis
h b
etw
een
the
cell
po
pu
lati
on
un
der
go
ing
mo
rph
olo
gic
al c
han
ges
an
dce
lls
un
der
go
ing
ap
op
tosi
s.T
his
co
uld
lea
d t
o n
on
-val
idco
ncl
usi
on
s ab
ou
t n
ano
tub
eto
xic
ity
.
Hig
h
Lo
w
Lo
w
Mo
der
ate
Hig
h
Th
e re
sear
ch o
f th
e se
ed b
y D
inu
an
d
Ro
jan
asak
ul
pro
po
ses
an a
lter
nat
e w
ay
of
dev
elo
pin
g t
his
sen
sor,
an
d c
ou
ld b
e in
corp
ora
ted
in
to I
RT
3 t
o p
rov
ide
an
alte
rnat
e p
ath
to
th
e fi
nal
go
al.
Wil
l co
nsu
lt w
ith
NIO
SH
ab
ou
t th
e id
eal
con
fig
ura
tio
n f
or
the
spec
ific
typ
es o
f te
sts
they
bel
iev
e ar
e m
ost
im
po
rtan
t. T
his
wil
lh
elp
fo
cus
the
effo
rt a
nd
mak
e th
e fi
nal
d
evic
e m
ore
mar
ket
able
an
d u
sefu
l to
re
sear
cher
s an
d c
on
sum
ers.
Pro
vid
e ad
equ
ate
pH
co
ntr
ol
wit
h b
uff
ers,
rath
er t
han
CO
2 g
as; p
rov
ide
slo
w c
ircu
la-
tio
n o
f m
edia
, rat
her
th
an s
tati
c in
cub
atio
n
If c
ells
do
no
t re
spo
nd
dir
ectl
y t
o c
om
-p
ou
nd
, dev
elo
p a
lin
ked
sig
nal
tra
nsd
uc-
tio
n b
ased
on
en
gin
eere
d d
etec
tors
(su
chas
ap
tam
ers)
Dev
elo
p a
mea
ns
to a
mp
lify
th
e si
gn
al,
such
as
ho
rser
adis
h p
ero
xid
ase
con
jug
ated
anti
bo
dy
-bas
ed l
um
ines
cen
ce
Ad
dit
ion
al t
ox
icit
y e
xp
erim
ents
wil
l b
ep
erfo
rmed
. S
pec
ifica
lly
, cel
ls w
ill
be
incu
bat
ed w
ith
sin
gle
wal
led
car
bo
n n
ano
tub
es f
or
0, 1
2,24
, 48,
an
d 7
2 h
, su
bse
qu
entl
y s
tain
edu
sin
g l
ife
and
dea
th c
ell
assa
ys
and
o
bse
rved
via
flu
ore
scen
ce m
icro
sco
py
.
Med
ium
Hig
h
Hig
h
Mo
der
ate
Hig
h
IRT
3:
Cel
lula
r S
enso
rs(W
VU
) C
on
t.
IRT
3 (M
U)
See
d:
Din
u/
Ro
jan
asak
ul
Component
Condition
Consequence
Impact
Likelihood
Mitigation
twen
ty-f
ou
r
It c
an b
e d
ifficu
lt t
o
det
erm
ine
the
mec
han
ism
s o
f n
ano
tub
e ce
llu
lar
up
tak
e in
rea
l-ti
me.
Lim
itat
ion
s in
ap
tam
erse
lect
ion
mak
e th
e se
n-
sor
app
lica
ble
to
a s
mal
ln
um
ber
of
ster
oid
alco
mp
ou
nd
s
Pro
po
sals
are
no
t co
mp
etit
ive
Man
usc
rip
ts n
ot
pu
bli
shed
Co
llab
ora
tiv
e to
ols
n
ot
resp
on
siv
e to
co
mm
un
ity
nee
ds
Co
llab
ora
tiv
e to
ols
are
pro
pri
etar
y o
r n
ot
exte
nsi
ble
Fea
ture
cre
ep i
n
coll
abo
rati
ve
or
vis
ual
izat
ion
to
ol
sco
pe
If w
e ca
nn
ot
dis
tin
gu
ish
b
etw
een
cel
lula
r u
pta
ke
by
pie
rcin
g v
s. b
y e
nd
ocy
tosi
s,
it w
ill
be
diffi
cult
to
dev
elo
pst
rate
gie
s to
mit
igat
e th
e ca
rbo
n n
ano
tub
e to
xici
tyan
d/o
r fu
rth
er p
urs
ue
the
mec
han
ism
s fo
r sp
ecifi
c to
xici
ty.
Wil
l li
mit
th
e ap
pli
cab
ilit
y o
fth
e se
nso
r.
Pro
po
sals
are
no
t fu
nd
ed
Gra
nts
wil
l n
ot
be
com
pet
itiv
e
Co
llab
ora
tiv
e fr
amew
ork
is
un
der
uti
lize
d
Co
llab
ora
tiv
e fr
amew
ork
is
un
der
uti
lize
d
Co
mm
un
ity
req
ues
ts f
or
fun
ctio
n e
xcee
d f
un
din
g
Hig
h
Med
ium
Mo
der
ate
Lo
w
Med
ium
Med
ium
Lo
w
Ad
dit
ion
al e
xper
imen
ts w
ill
be
per
form
edu
sin
g a
tom
ic f
orc
e m
icro
sco
py
to
det
er-
min
e ch
ang
es i
n t
he
cell
mo
rph
olo
gy
up
on
exp
osu
re. C
ell
mo
rph
olo
gy
up
on
nan
otu
be
exp
osu
re w
ill
be
com
par
ed w
ith
cell
mo
rph
olo
gy
of
con
tro
l sa
mp
les.
Hig
hm
orp
ho
log
ical
ch
ang
es o
r “h
ole
s” i
nto
cel
lm
emb
ran
e w
ou
ld c
on
firm
cel
lula
r en
do
cyto
sis.
In r
elat
ed w
ork
, th
e P
Is h
ave
fou
nd
th
atth
e se
lect
ion
can
be
eng
inee
red
to
det
ect
exp
losi
ves
in
en
vir
on
men
tal
sam
ple
s, g
iv-
ing
th
e p
roje
ct a
n a
lter
nat
ive
via
ble
tar
get
that
is
also
of
gre
at c
on
cern
fo
r se
curi
tyan
d e
nv
iro
nm
enta
l ap
pli
cati
on
s.
Imp
lem
ent
in-h
ou
se a
nd
ext
ram
ura
l p
re-s
ub
mis
sio
n r
evie
w
Pro
vid
e m
ento
rsh
ip a
nd
tea
chin
g r
elea
sefo
r R
II s
up
po
rted
fac
ult
y
Insu
re t
hat
to
ol
pro
toty
pes
are
d
emo
nst
rate
d e
arly
an
d i
tera
tiv
ely
im
pro
ved
Bu
ild
on
pro
ven
exp
erti
se, e
.g.,
the
Wo
rk-
too
ls e
xper
ien
ce a
nd
th
e C
HE
F t
eam
Co
mm
un
icat
e fe
atu
re s
et d
escr
ipti
on
an
dd
emo
nst
rate
wo
rkin
g p
roto
typ
es; d
ocu
-m
ent
des
ired
fea
ture
s n
ot
incl
ud
ed a
nd
com
mu
nic
ate
them
to
th
e C
on
sort
ium
.
See
d:
Din
u/
Ro
jan
asak
ul
Co
nt.
See
d:
Ho
llan
d/
So
ote
r
Em
erg
ing
them
e
Co
llab
ora
tio
nan
d
Vis
ual
izat
ion
Co
mp
on
ent
Co
nd
itio
nC
on
seq
uen
ceIm
pac
tL
ikel
iho
od
Mit
igat
ion
Hig
h
Med
ium
Hig
h
Hig
h
Hig
h
Mo
der
ate
twen
ty-fi
ve
Co
mp
on
ent
Co
nd
itio
nC
on
seq
uen
ceIm
pac
tL
ikel
iho
od
Mit
igat
ion
Fac
ult
y
Hir
ing
: B
ioin
form
atic
sP
rofe
sso
r(W
VS
U)
Tw
o f
acu
lty
(MU
) C
ellu
-la
r/M
ole
cula
rM
ech
anis
ms
Sh
ared
F
acil
itie
s
Nex
t G
ener
atio
nS
equ
ence
r(M
U)
Cy
ber
-in
fras
tru
ctu
re
Hir
ing
of
this
fac
ult
ym
emb
er d
oes
no
t o
ccu
ru
nti
l 12
-24
mo
nth
s la
ter
fro
m o
rig
inal
pro
po
sed
dat
e
Del
ays
in h
irin
g
Lac
k o
f ab
ilit
y t
o r
eco
ver
cost
s v
ia u
ser
fees
an
dco
st s
har
e
Insu
ffici
ent
fun
ds
to d
e-v
elo
p n
ew u
sers
an
dp
roje
cts
Lac
k o
f u
sers
Cu
rric
ulu
m i
n b
ioin
form
atic
sis
no
t av
aila
ble
to
stu
den
ts /
Res
earc
h a
nd
ass
oci
ated
ac
tiv
itie
s ar
e n
ot
con
du
cted
as
pro
po
sed
.
Co
llab
ora
tio
ns
and
res
earc
hp
rod
uct
ivit
y m
etri
cs a
re n
ot
met
Ab
ilit
y t
o r
etai
n s
taff
an
d
serv
ice
con
trac
ts o
n
inst
rum
ents
is
jeo
par
diz
ed;
sust
ain
abil
ity
is
no
t ac
hie
ved
Inv
estm
ent
in “
fiel
d b
iolo
gy
gen
om
ics”
wil
l n
ot
bea
r fr
uit
Inv
estm
ent
no
t fu
lly
u
tili
zed
an
d c
om
pu
tati
on
sn
ano
mat
eria
ls c
om
mu
nit
yd
oes
no
t d
evel
op
Mo
der
ate
Med
ium
Med
ium
Med
ium
Med
ium
Med
ium
Med
ium
Hig
h
Mo
der
ate
Med
ium
Wh
ile
this
per
man
ent
facu
lty
po
siti
on
is
fill
ed, t
he
nee
d c
an b
e te
mp
ora
rily
met
by
hir
ing
a p
ost
-do
cto
ral
emp
loy
ee t
o p
rov
ide
sup
po
rt t
o t
he
pro
po
sed
act
ivit
ies
in
rela
tio
n t
o t
his
po
siti
on
.
Ad
d t
arg
eted
rec
ruit
men
t to
wid
ely
-ad
ver
tise
d a
pp
roac
h
Inst
itu
ted
new
sy
stem
fo
r ch
arg
ing
th
atta
kes
dir
ect
cost
s in
to a
cco
un
t fo
r ea
ch
inst
rum
ent,
in
clu
din
g s
taff
tim
e, s
erv
ice
con
trac
ts, c
on
sum
able
s, a
nd
tra
inin
g.
Wil
lre
vis
e ra
tes
in O
cto
ber
201
1 an
d p
roje
ct f
or
rest
of
fisc
al y
ear
to e
nsu
re s
ust
ain
abil
ity
.
See
k i
ntr
amu
ral
and
ext
ram
ura
l fu
nd
ing
Ad
dit
ion
al w
ork
sho
ps
wil
l b
e sc
hed
ule
d
to e
xpo
se f
acu
lty
to
th
e en
han
ced
CI,
an
dto
dem
on
stra
te t
hat
co
mp
uta
tio
nal
stu
die
sca
n b
e v
alu
able
to
th
eir
rese
arch
pro
gra
ms.
Co
mp
uta
tio
nal
fac
ult
y h
ires
in
ph
ysi
cs,
chem
istr
y a
nd
en
gin
eeri
ng
in
201
2 w
ill
hel
p i
ncr
ease
fac
ilit
y u
sag
e. S
eed
fu
nd
ing
may
be
use
d t
o e
nco
ura
ge
coll
abo
rati
on
b
etw
een
exp
erim
enta
list
s an
d
com
pu
tati
on
al s
cien
tist
s.
twen
ty-s
ix
Co
mp
on
ent
Co
nd
itio
nC
on
seq
uen
ceIm
pac
tL
ikel
iho
od
Mit
igat
ion
Lea
rnin
g
Ass
ista
nts
(LA
)
TR
EK
Tea
cher
an
dS
tud
ent
Su
mm
er
Res
earc
hp
rog
ram
An
in
suffi
cien
t n
um
ber
of
lear
nin
g a
ssis
tan
ts a
rere
cru
ited
.
LA
s se
lect
ed d
o n
ot
per
-fo
rm t
o t
he
sati
sfac
tio
no
f fa
cult
y o
ver
seei
ng
cou
rses
.
Lac
k o
f in
tere
sted
an
dco
mm
itted
tea
cher
s to
par
tici
pat
e
Lac
k o
f ab
ilit
y t
o r
ecru
itst
ud
ents
to
par
tici
pat
e
Lac
k o
f R
II R
esea
rch
ers
wil
lin
g t
o a
ccep
t T
RE
Kp
arti
cip
ants
Th
e p
rog
ram
can
no
t o
per
ate
at f
ull
str
eng
th a
nd
th
us
its
imp
act
is m
ute
d, a
s n
ot
asm
any
stu
den
ts a
re r
each
ed.
Dep
artm
ents
can
cel
or
de-
crea
se p
arti
cip
atio
n i
n t
he
LA
pro
gra
m a
nd
/or
the
pro
gra
mfa
ces
facu
lty
op
po
siti
on
.
Red
uce
d i
mp
act
of
pro
gra
m
Tea
cher
par
tici
pan
t w
ith
ou
tst
ud
ent
cou
ld r
edu
ce
clas
sro
om
su
pp
ort
Lac
k o
f la
bs
to p
lace
teac
her
/stu
den
t p
airs
fo
rT
RE
K r
edu
ces
the
nu
mb
er o
f
Med
ium
Hig
h
Lo
w
Lo
w
Lo
w/
mo
der
ate
Med
ium
Med
ium
Mo
der
ate
Mo
der
ate
Mo
der
ate
Th
e E
du
cati
on
/Ou
trea
ch c
oo
rdin
ato
rs w
ill
incr
ease
eff
ort
s to
wo
rk c
lose
ly w
ith
th
ep
arti
cip
atin
g d
epar
tmen
ts a
nd
fac
ult
yle
ader
to
en
sure
th
e se
lect
ion
of
suffi
cien
tq
ual
ity
an
d q
uan
tity
of
stu
den
ts t
o s
taff
th
ep
rog
ram
. R
ecru
itm
ent
stra
teg
ies
such
as
Soci
ety
of
Ph
ysi
cs S
tud
ents
mee
tin
gs,
A
sso
ciat
ion
of
Wo
men
in
Sci
ence
mee
tin
gs,
and
oth
er m
eeti
ng
s o
f h
igh
ly m
oti
vat
ed
un
der
gra
du
ates
wil
l b
e u
sed
.
LA
Fac
ult
y l
ead
ers
and
Ed
uca
tio
n/
Ou
trea
ch c
oo
rdin
ato
rs w
ill
imp
rov
e th
ep
rep
arat
ion
co
nd
itio
ns
of
the
LA
s to
en
sure
that
th
ey a
re a
deq
uat
ely
pre
par
ed t
o
exec
ute
th
eir
du
ties
.
Op
en p
osi
tio
ns
wil
l b
e fi
lled
th
e fo
llo
win
gsu
mm
er w
ith
a m
ax. O
f 1
add
itio
nal
teac
her
/stu
den
t p
air/
yea
r. A
dd
itio
nal
re
cru
itm
ent
thro
ug
h h
igh
sch
oo
l v
isit
s an
d c
ross
pro
ject
pla
nn
ing
/ co
ord
inat
ion
for
pla
cem
ent
of
rese
arch
ers
fro
m m
ult
iple
pro
gra
ms
wil
l im
pro
ve
the
pro
cess
.
Mo
ney
fro
m m
issi
ng
stu
den
ts w
ill
be
uti
lize
d f
or
add
itio
nal
su
pp
ort
mec
han
ism
in t
he
clas
sro
om
. A
dd
itio
nal
rec
ruit
men
tm
ech
anis
ms
wil
l fo
cus
recr
uit
men
t o
nte
ach
ers
clo
ser
to p
arti
cip
atin
g c
amp
use
s
Res
earc
her
s o
uts
ide
of
the
RII
hav
e b
een
uti
lize
d t
his
firs
t su
mm
er a
t W
VU
. F
utu
reco
ord
inat
ion
eff
ort
s b
etw
een
th
is a
nd
oth
er
twen
ty-s
evenC
om
po
nen
tC
on
dit
ion
Co
nse
qu
ence
Imp
act
Lik
elih
oo
dM
itig
atio
n
un
der
gra
du
ate/
gra
du
ate/
ou
trea
ch r
esea
rch
pro
gra
ms
wil
l p
re-a
ccep
t p
arti
cip
ants
in
tola
bs
in a
n a
ttem
pt
to d
istr
ibu
te t
he
par
tici
-p
atin
g a
cro
ss a
bro
ad r
ang
e o
f fa
cult
y.
Wh
ile
cou
rses
are
bei
ng
dev
elo
ped
at
WV
SU
, oth
er s
ou
rces
, to
tem
po
rari
ly
sup
ple
men
t th
e n
eed
, can
be
exp
lore
dth
rou
gh
MU
an
d o
ther
in
stit
uti
on
al
par
tner
ship
s.
Lo
ng
-ter
m a
rran
gem
ents
to
su
pp
lem
ent
thes
e co
urs
es w
ill
hav
e to
be
mad
e th
rou
gh
MU
an
d o
ther
in
stit
uti
on
al p
artn
ersh
ips.
Imp
lem
ent
ou
trea
ch a
ctiv
itie
s to
acr
oss
th
e st
ate
to i
nfo
rm S
TE
M-b
ased
bu
sin
esse
so
f th
e o
pp
ort
un
itie
s at
Mar
shal
l
Incr
ease
men
tori
ng
eff
ort
s w
ith
PU
I/C
TC
PIs
an
d w
ith
co
rres
po
nd
ing
in
stit
uti
on
alad
min
istr
atio
n (
to n
ego
tiat
e re
du
ced
te
ach
ing
lo
ads
and
gra
nt
adm
inis
trat
ion
)
Wee
kly
gro
up
mee
tin
gs
are
bei
ng
im
ple
men
ted
to
en
sure
th
at s
tud
ents
ar
e m
on
ito
red
. If
a s
tud
ent
star
ts t
o f
all
beh
ind
in
co
urs
es a
nd
/or
rese
arch
, th
e E
du
cati
on
/ O
utr
each
co
ord
inat
or
wil
l d
evel
op
an
in
div
idu
aliz
ed p
lan
th
at
iden
tifi
es t
he
area
s in
wh
ich
th
e st
ud
ent
is s
tru
gg
lin
g a
nd
pro
vid
es a
ssis
tan
ce i
n
term
s o
f tu
tori
ng
an
d/o
r m
ento
rin
g.
TR
EK
Tea
cher
an
dS
tud
ent
Co
nt.
Wo
rkfo
rce:
M
.A. B
iote
ch/
Bu
sin
ess
Tra
ck(W
VS
U)
MB
A
Pro
gra
m f
or
scie
nce
gra
ds
(MU
)
PU
I/C
TC
In
cub
ato
r
Gra
du
ate
Fel
low
ship
Pro
gra
m(G
FP
)
Bu
sin
ess
cou
rses
are
no
tm
ade
avai
lab
le a
t W
VS
Uw
ith
in t
he
nex
t 24
mo
nth
s
Bu
sin
ess
cou
rses
are
no
tm
ade
avai
lab
le a
t W
VS
U
Insu
ffici
ent
enro
llm
ent
Su
pp
ort
do
es n
ot
lead
to
new
ext
ram
ura
l fu
nd
ing
or
incr
ease
s p
rod
uct
ivit
y
Gra
du
ate
Fel
low
s d
o n
ot
mak
e su
ffici
ent
pro
gre
sso
n c
ou
rsew
ork
, an
d/o
rre
sear
ch.
par
tici
pan
ts w
e ar
e ca
pab
le o
fac
cep
tin
g
Th
e p
rop
ose
d t
rack
wil
l b
e d
elay
ed a
nd
no
t i
mm
edia
tely
avai
lab
le t
o n
ew e
nro
lled
st
ud
ents
in
th
e B
iote
ch
pro
gra
m a
t W
VS
U
Th
e p
rop
ose
d t
rack
wil
l h
ave
to b
e o
ffer
ed u
sin
g e
xter
nal
re
sou
rces
Ad
min
istr
ativ
e w
ith
dra
wal
of
inst
itu
tio
nal
su
pp
ort
Lo
ng
ter
m s
ust
ain
abil
ity
at
WV
’s C
TC
s an
d P
UIs
wil
l n
ot
be
ach
iev
ed
Fel
low
ship
s ar
e n
ot
ren
ewed
and
/or
Fel
low
s d
o n
ot
con
tin
ue
wit
h n
ano
mat
eria
lsre
sear
ch
Med
ium
Med
ium
Mo
der
ate
Hig
h
Hig
h
Hig
h
Lo
w
Mo
der
ate
Mo
der
ate
Med
ium
twen
ty-e
igh
tCo
mp
on
ent
Co
nd
itio
nC
on
seq
uen
ceIm
pac
tL
ikel
iho
od
Mit
igat
ion
Gra
du
ate
Fel
low
ship
Pro
gra
m(G
FP
) C
on
t.
Div
ersi
ty
Man
agem
ent
Th
e G
FP
co
ho
rt l
ack
s d
iver
sity
.
UR
EP
ST
EM
Stu
den
t re
ten
tio
n n
ot
incr
ease
d
Un
exp
ecte
d d
epar
ture
o
f le
ader
ship
per
son
nel
We
fail
to
fu
lfill
ou
r co
mm
itm
ent
and
res
po
nsi
bil
ity
to i
ncr
ease
th
e d
iver
sity
of
ST
EM
res
earc
her
s
We
fail
to
fu
lfill
ou
r co
mm
it-
men
t an
d r
esp
on
sib
ilit
y t
o
incr
ease
th
e re
ten
tio
n o
f d
iver
se u
nd
erg
rad
uat
e S
TE
Mst
ud
ents
Lac
k o
f g
uid
ance
fo
r p
roje
ctim
ple
men
tati
on
Hig
h
Hig
h
Hig
h
Hig
h
Med
ium
Lo
w
We
hav
e id
enti
fied
in
ten
sify
ing
rec
ruit
ing
of
un
der
rep
rese
nte
d g
rou
ps
for
the
sum
mer
un
der
gra
du
ate
rese
arch
p
rog
ram
s as
a p
rio
rity
. C
ou
ple
d w
ith
in
crea
sed
rec
ruit
ing
of
tho
se s
tud
ents
to
gra
du
ate
sch
oo
l, w
e ca
n m
axim
ize
div
ersi
ty, a
s th
e u
nd
erg
rad
uat
e re
sear
chst
ud
ents
are
sig
nifi
can
tly
mo
re d
iver
seth
an t
he
gra
du
ate
stu
den
t b
od
y.
Cen
tral
offi
ce s
taff
wil
l in
crea
se e
ffo
rts
tow
ork
clo
sely
wit
h C
om
mis
sio
n l
ead
ersh
ipto
en
sure
th
e co
ord
inat
ion
of
the
Ch
ance
llo
r’s
Div
ersi
ty I
nit
iati
ve
and
W
VI3
Th
ink
Tan
k e
ffo
rts
as w
ell
as
uti
lize
th
e ex
per
ien
ce a
nd
exp
erti
se o
f n
atio
nal
lea
der
s in
ST
EM
stu
den
t re
ten
tio
nto
dev
elo
p b
etter
ret
enti
on
eff
ort
s ac
ross
inst
itu
tio
ns.
Cen
tral
offi
ce s
taff
wil
l ap
ply
for
exte
rnal
fu
nd
ing
to
su
pp
ort
ST
EM
re
ten
tio
n i
nit
iati
ves
as
wel
l as
co
ord
inat
etr
ack
ing
of
ST
EM
stu
den
ts w
ith
th
e D
ivis
ion
of
Po
licy
an
d P
lan
nin
g.
Tra
in y
ou
ng
cen
tral
offi
ce s
taff
an
d t
enu
red
fa
cult
y a
t u
niv
ersi
ties
in
lea
der
ship
. S
ucc
essi
on
pla
n i
n p
lace
.
