Biomonitoring air pollution

Paulo Saldiva

Institute of Advanced Studies – USP

pepino@usp.br

Clinics (Sao Paulo) v.66(6); 2011 Jun PMC3129956

1819 1819 1819N =

DirtyClean

10

8

6

4

2

0

-2

births

late

early

736796645969N =

GROUP

NNFNFFNNNFFNFNNFFF

FE

TA

L W

EIG

HT

(g

ram

s)

1,8

1,6

1,4

1,2

1,0

,8

374596184169N =

GROUP

NNFNFFNNNFFNFNNFFF

PL

AC

EN

TA

L W

EIG

HT

(g

ram

s)

,14

,13

,12

,11

,10

,09

21-30d11-20d6-10d3-5d0-2d

age categories

14

12

10

8

6

4

2

0

Me

an

+-

2 S

E b

od

y w

eig

ht

(g) gestation + post natal

post natal

gestation

filtered

Filtered Ambient

placenta

-10 -9 -8 -7 -6 -5 -4-100

-75

-50

-25

0

Exposto (n=11)

Controle (n=9)

*

** *

Isoproterenol (Log M)

Rela

xam

en

to (

%)

-9 -8 -7 -6 -5 -4-100

-75

-50

-25

0

Exposto (n=12)

Controle (n=9)

** * *

Acetilcolina (Log M)

Rela

xam

en

to (

%)

Environ Res. 2019 Jun;173:23-32.

Spatial

distribution of

nitrogen dioxide

in São Paulo

(according to

Ribeiro et al.,

2019)

RIBEIRO et al. Incidence and mortality for

respiratory cancer and traffic-related air

pollution in São Paulo, Brazil. Environmental

Research 170:243-251, 2019

Odds ratio for

anthracosis,

controlling for:

- Age,

- Time living in SP,

- Tobacco load,

- Passive

smoking,

- Road density,

- Distance to the

large roads,

- Socioeconomic

index

MODAU Team (unpublished)

The problem – An overview

The problem – An overview

ePM2,5 = (7,5 x índice de refletância) + 10

CE = ePM2,5 x Δt(a)

r = -0,52 p < 0,001

r = -0,63 p < 0,001

Instituto Nacional de Análise Integrada do Risco Ambiental – INCT

Environ Res. 2019 Jul;174:88-94. doi: 10.1016/j.envres.2019.04.021. Epub 2019 Apr 25.

Environ Health Perspect. 2017 Apr;125(4):753-759.

New initiative

Association between micronuclei frequency in pollen mother cells of Tradescantia and mortality due to cancer and cardiovascular diseases: A preliminary study in Sao José dos Campos, Brazil

aDepartment of Geochemistry, Fluminense Federal University (UFF), Niteroi, RJ, Brazil bNational Institute for Space Research, Sao José dos Campos, SP, Brazil cExperimental Air Pollution Laboratory, Department of Pathology, Sao Paulo University Medical School, Sao Paulo, Brazil dDepartment of Biological Sciences, Western Illinois University, Macomb, IL 61455, USA Environ Pollut. 2009 Jun;157(6):1767-70.

4,003,503,002,502,00

micronuclei (%)

6,00

5,00

4,00

3,00adju

sted

mor

tality

rate

for n

eopl

asia

(dea

ths/

10,0

00 in

habi

tant

s)

Environ Int. 2016 May;91:271-5