Biomarkers indiabetes:analytical and clinical perspectives

February 23 - 24, 2017 · Hotel Crowne Plaza · Belgrade, Serbia

U N D E R T H EA U S P I C E S O F

PROGRAMMEU N D E R T H E A U S P I C E S O F

ORGANIZERS

Clinical Center of Serbia,Center for Medical Biochemistry andClinic for Endocrinology, Diabetes and Metabolic Disorders

COORGANIZERS

Serbian Diabetes Society

Board on Cardiovascular Pathology of theSerbian Academy of Sciences and Arts

AUSPIECES

2nd Serbian Biomarkers SymposiumBiomarkers in diabetes: analytical and clinical perspectivesis organized under the auspices of

International Federation of Clinical Chemistryand Laboratory Medicine (IFCC)

European Federation of Clinical Chemistryand Laboratory Medicine (EFLM)

European Society of Pharmacogenomicsand Personalised Therapy (ESPT)

Ministry of Health of the Republic of Serbia

Ministry of Education, Science and Technological Development of Serbia

UNDER HONORARY PATRONAGE

TRH Crown Prince Alexander and Princess Katherine Karadjordjevic

Dear Colleagues and Friends,

It is a great pleasure and honor to invite you to the 2nd Serbian Biomarker

Symposium (SERBIS) that will be held in Belgrade, Serbia, on February 23-24, 2017.

This international symposium is arranged to bridge clinical and laboratory work,

emphasizing the importance of teamwork and interactions between all

professionals involved in the �ght against diabetes mellitus and personalized

medicine approach. The 2nd SERBIS with the overall theme Biomarkers in diabetes:

analytical and clinical perspectives is intended to display the state of the biomarker

use at the interface between diabetes mellitus and laboratory medicine.

This symposium will bring together international experts who will provide a

comprehensive and up-to-date overview of recent advances in the �eld of

integrated biomarker assessment and quali�cation in the context of diagnosis,

treatment, and prevention of diabetes. Our innovative and original programme this

year promises to be challenging and stimulating as we consider key topics of

interest and concern, covering a range of topical and relevant issues which a�ect us

all from the laboratory to the clinic.

The most recent advances in the management of diabetes focusing on HbA1c and

new biomarkers will be presented, followed by pharmacogenomic �ndings which

will greatly improve the e�cacy of diabetes treatment.

We are convinced that SERBIS will be top level educational and scienti�c event in

our region, giving to the participants an excellent opportunity for education and

chance for improvement of personal achievements. It will o�er a unique

opportunity to identify new research ideas and establish collaboration with

colleagues from di�erent countries. Also, to keep up to date with Industry partners

who will showcase their latest advances on their booths in bio-technology

innovations, novel assays and therapies in diabetes �eld.

We hope that SERBIS will meet your expectations, provide you some unforgettable

personal and professional memories, and trust that you will enjoy your visit to the

very beautiful and exciting cosmopolitan city of Belgrade.

We look forward to welcoming you in Belgrade.

Sincerely yours,

Milika AsaninNebojsa M. LalicSanja Stankovic

HONORARY COMMITTEE

Asst. dr Zlatibor LoncarMinister of Health of the Republic of Serbia

Mladen SarcevicMinister of Education, Science and Technological Development of the Republic of Serbia

Academician Vladimir KosticPresident of Serbian Academy of Sciences and Arts

Academician Dragan MicicPresident of Serbian Health Council

Academician Vladimir KanjuhPresident, Board on Cardiovascular Pathology of the Serbian Academy of Sciences and Arts

Academician Ljubisa RakicPresident, Board on Biomedical Investigation of the Serbian Academy of Sciences and Arts

Academician Radoje ColovicPresident of Serbian Medical Association

Academician Vladimir BumbasirevicRector, University of Belgrade

Academician Jovan Hadzi-Dzokic

Academician Nebojsa LalicDean, University of Belgrade, School of Medicine

Prof. dr Zorica VujicDean, University of Belgrade, School of Pharmacy

SCIENTIFIC COMMITTEE

Milika AsaninAntonio Ceriello

Joris DelangheEmma English

Michèle FonfredePhilippe Gillery

Garry JohnAleksandra Jotic

Patricia KaiserVladimir Kanjuh

Eric KilpartickKatarina Lalic

Nebojša M. LalicPaivi Laitinen

Erna Lenters-Westra Randie Little Dragan Micic

Andrea MoscaDavid Sacks

Sverre SandbergRon van Schaik Petar Seferovic

Goran StankovicSanja Stankovic

Cas Weykamp

ORGANIZING COMMITTEE

Daniela BartolovicAndjelo BeleticEmina ColakAnica DjordjevicJelica DjordjevicRadica DunjicOlja GabricJasna IlicMirjana MilivojevicRadmila ObrenovicGordana StosicTatjana VodnikDragana Vukosavljevic

WEDNESDAY, FEBRUARY 22, 20172nd SERBIS ProgrammeBiomarkers in diabetes: analytical and clinical perspectives

15:00-16:15 Special Pre-Symposium Session

Chair: Sanja Stankovic

15.00-15.30 Antionio Ceriello (Italy)Markers of glycemic control

15:30-16:00 Nebojsa M.Lalic (Serbia)Individual treatment goals in diabetes: the role of biomarkers

16:00-16:15 Q&A (Discussion)

THURSDAY, FEBRUARY 23, 2017 08:30 - 10:00 Registration OPENING CEREMONY 10:00-10:30 Welcome note 10:30-11:00 Cocktail

THURSDAY, FEBRUARY 23, 2017Session 1

Chairs: Garry John, Nebojsa M. Lalic 11:00-11:30 Garry John (UK)A general history of HbA1c from 1960s to 2016

11:30-12:00 David Sacks (USA)HbA1c in diabetes and pre diabetes diagnosis

12:00-12:30 Nebojsa M. Lalic (Serbia)Diagnosis of diabetes: achievements and pitfalls

12:30-12:40 Q&A (Discussion) Chairs: Ron van Schaik, Sanja Stankovic 12:40-13:10 Ron van Schaik (The Netherlands) Pharmacogenetics in diabetes: where do we stand?

13:10-13:40 Sanja Stankovic (Serbia)Pharmacogenetics of metformin response:current evidence and future prospects

13:40-13:50 Q&A (Discussion) 13:50-14:50 Lunch

THURSDAY, FEBRUARY 23, 2017Session 2

Chairs: Sverre Sandberg, Eric Kilpatrick 14:50-15:20 Erna Lenters-Westra (The Netherlands)Standardization of HbA1c assays

15:20-15:50 Cas Weykamp (The Netherlands)Performance criteria of HbA1c assay devices

15:50-16:20 Sverre Sandberg (Norway)POCT of HbA1c: advantages and pitfalls

16:20-16:50 Emma English (UK)Which lessons from meta-analyses on HbA1c?

16:50-17:20 Eric Kilpatrick (Qatar)Clinical outcomes of HbA1c standardization

17:20-17:30 Q&A (Discussion)

FRIDAY, FEBRUARY 24, 2017Session 3

Chairs: Cas Weykamp, Andrea Mosca

10:00-10:30 Randie Little (USA)The NGSP experience of HbA1c

10:30-11:00 Patricia Kaiser (Germany)Challenges in HbA1c evaluation by LC/MS

11:00-11:30 Andrea Mosca (Italy)Impact of Hb variants and RBC disorders on HbA1c interpretation

11:30-11:40 Q&A (Discussion) 11:40-11:50 Co�e break

FRIDAY, FEBRUARY 24, 2017Session 4

Chairs: Philippe Gillery, Joris Delanghe 11:50-12:20 Fonfrede Michèle (France)Other markers or short-term glycation:fructosamine, glycated albumin, 1,5-anhydroglucitol

12:20-12:50 Philippe Gillery (France)Advanced glycation end products as biomarkers in diabetesmellitus and chronic diseases

12:50-13:20 Joris Delanghe (Belgium)Keratin glycation as a biomarker for diabetes

13:20-13:50 Aleksandra Jotic (Serbia)Diabetes in pregnancy: the relevance of standard markersof glucose control

13:50-14:00 Q&A (Discussion) 14:00-15:00 Lunch

FRIDAY, FEBRUARY 24, 2017Session 5

Chairs: Vladimir Kanjuh, Dragan Micic 15:00-15:30 Vladimir Kanjuh (Serbia)Causes, histopathology and consequences of vascularlesions in diabetes mellitus type 2 15:30-16:00 Dragan Micic (Serbia)Obesity, diabetes and cardiovascular risk markers

16:00-16:30 Katarina Lalic (Serbia)Lipid abnormalities in diabetes: LDL or nonHDL?

16:30-17:00 Petar Seferovic (Serbia)Metabolic factors in cardiac failure

17:00-17:30 Paivi Laitinen (Finland)Cardiac troponin and diabetes

17:30-18:00 Goran Stankovic (Serbia)Predictors of stent thrombosis

18:00-18:10 Q&A (Discussion) 18:10-18:40 Summary and closing of the symposium

Hotel Crowne Plaza

4 star hotel in Belgrade.

Hotel address: Vladimira Popovica 10 Street, 11 070 Belgrade, Serbia

Phone: +381 11 2204-115, fax: +381 11 2204-104

E-mail: begcp.frontdesk@ihg.com

Web: www.ihg.com

Registration is free of charge and includes:

- Participation in all lectures

- Course material

- Registration material

- Access to exhibition

- Certi�cate of attendance

- Welcome cocktail

- Everyday lunch in Crown Plaza Hotel

- Refreshments with drinks and snacks

LANGUAGEThe o�cial language of the Symposium is English.

CURRENCYThe Serbian currency is Serbian Dinar (abbreviated as RSD). Current exchange rate is

about 124 RSD for 1 Euro. Credit cards (VISA, Euro card, MasterCard, American

Express, Diners Club) are accepted in most shops. Automated Teller Machines

(ATMs) and Exchange o�ces are also available in the Hotel. For detailed information

contact Hotel reception.

PUBLIC TRANSPORTATIONBus lines 74, 88, 95, as well as tram lines 7, 7L, 9, 11, and 13 connect the Crowne

Plaza Hotel with the City. The free multiple use tickets can be acquired at

registration desk. Taxis are available throughout the City of Belgrade, and also in

front of the Crowne Plaza Hotel.

WEATHER FORCASTDuring the two days of the Symposium mostly cloudy weather is expected, and

daily temperatures ranging from 0-3°C (source: www.accuweather.com).

SCIENTIFIC SECRETARIATSanja Stankovic, Clinical Center of Serbia,

Address: Višegradska 26, 11000 Belgrade, Serbia.

Phone/Fax: +381-11-361-5631,

Mobile phone: +381-63-237449.

E-mail: sanjast2013@gmail.com

TRAVEL AGENCYFor hotel reservations and travel arrangements please contact

Ms. Radmila Maricic - SMART TRAVEL PCO

Address: Njegoseva 72 a, 11000 Belgrade

Phone: (+ 381) 11 770 2184, (+ 381) 11 770 2522

Mobile phone: +381 63 25 20 24

Fax: (+ 381) 11 244 7524

Email: radmila.maricic@smarttravelpco4.rs

Web: www.smarttravelpco4.rs

Accommodation of the faculty members is organized at the Hotel Crowne

Plaza. Transportation from the airport and from the hotel will be organized

for all invited speakers.

WiFiFree WiFi is provided for al Symposium participants.

REGISTRATION DESKRegistration desk will be opened on Thursday February 23rd 2017, from 8:30 AM.

Registration fee for participants is free of charge. Preregistered participants can

pick up their name badges and Symposium material at the Registration desk

from Thursday February 23rd 2017, 8:30 AM. Symposium speaker’s abstracts will

be available at Symposium web site www.serbis.rs.

CERTIFICATES OF ATTENDANCEThe Symposium program is accredited by the Serbian Health Council with 10

CME credit hours for participants and 15 for lecturers (No. 153-02-3989/2016-01,

Ev. No. Ц-1-93/17). Certi�cates of attendance will be available at the Registration

Desk, on Friday, February 24, 2017 from 06:00 PM.

SYMPOSIUM WEBSITE:www.serbis.rs

P L A T I N U M S P O N S O R

SPONSORSPRINCIPAL SPONSOR