Biology Essentials - 031 - bozemanscience · Biology Essentials - 031 Gene Regulation...
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Biology Essentials - 031 Gene Regulation bozemanscience.com
Transcript of Biology Essentials - 031 - bozemanscience · Biology Essentials - 031 Gene Regulation...
Gene regulation
Regulatory sequence
Regulatory gene
Bacteria Eukaryotes
Promoter
Positive Control
Negative Control
lac operon trp operon
Transcription factors
Activators Repressor
Terminology
Proteins
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Gene
TATA Box (Example)
Regulatory gene
Regulatory Protein
TATA Binding Protein (Example)
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Gene 1 Gene 2 Gene 3
The lac OperonTake Two:
in Bacteria
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Promoter Operator
Repressor(positive control)
lacZ lacY lacA
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Promoter Operator
Repressor(positive control)
lacZ lacY lacA
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Promoter Operator
Repressor(positive control)
lacZ lacY lacA
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trpE trpD trpC trpB trpA
Tryptophan Synthesis Genes
The trp OperonTake Two:
in Bacteria
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trpE trpD trpC trpB trpAPromoter Operator
Repressor (negative control)
Tryptophan
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trpE trpD trpC trpB trpAPromoter Operator
Repressor (negative control)
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trpE trpD trpC trpB trpAPromoter Operator
RNA Polymerase
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trpE trpD trpC trpB trpAPromoter Operator
RNA Polymerase
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Gene
PromoterEnhancers
Transcription Factors
RNA Polymerase
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Gene
PromoterEnhancers
Transcription Factors
RNA Polymerase
PromoterEnhancers
RNA Polymerase
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Bioinformatik, English: Jawahar Swaminathan and MSD staff at the European Bioinformatics InstituteDeutsch: Jawahar Swaminathan und MSD Mitarbeiter am Europäischen Institut für BioinformatikPlattdüütsch: Jawahar Swaminathan un de Lüüd von MSD an dat Europääsche Institut för. English: Cartoon Representation of the Molecular Structure of Protein Registered with 2nvw Code., [object HTMLTableCellElement]. English: http://www.ebi.ac.uk/pdbe-srv/view/images/entry/2nvw600.png, displayed on http://www.ebi.ac.uk/pdbe-srv/view/entry/2nvw/summary. http://commons.wikimedia.org/wiki/File:PDB_2nvw_EBI.jpg. DNA, n.d. http://openclipart.org/detail/58543/dna-by-kumar35885. “File:E Coli at 10000x, Original.jpg.” Wikipedia, the Free Encyclopedia, November 13, 2013. http://en.wikipedia.org/w/index.php?title=File:E_coli_at_10000x,_original.jpg&oldid=478393073. “File:Glass of Milk on Tablecloth.jpg.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Glass_of_milk_on_tablecloth.jpg. “File:Lac operon1.png.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Lac_operon1.png. “File:Protein TBP PDB 1c9b.png.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Protein_TBP_PDB_1c9b.png. “File:Ribosome mRNA Translation En.svg.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Ribosome_mRNA_translation_en.svg. Forluvoft. Simple Cartoon of Transcription Termination, October 9, 2007. Own work. http://commons.wikimedia.org/wiki/File:Simple_transcription_termination1.svg.
Acknowledgements
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