BTS VIII 04.13 0159

B. Tech. Degree VIII Semester Examination April 2013

CS/EB/EC/IT 804 (B) BIOINFORIVIATICS(2006 Scheme)

Time : 3 Hours Maximum Marks : 100

PART A(Answer ALL questions)

(8 x 5 = 40)I. Write short answers on:

Gen BankCentral dogma of molecular biologyBLOSUMClustalWBLAST

FASTAStar treesRasMol

PART B(4 x 15 = 60)

II. (a) Write briefly on web based proteomic databases. (7)(b) Explain DNA replication. (8)

ORIII. (a) Write a brief note on secondary databases. (7)

(b) Discuss protein synthesis. (8)

Explain global comparison for pairwise sequence alignment of two sequences. (15)OR

Write notes on: (15)PAMNeighbor-joining method

What are microarrays? Write about the microarray image analysis. (15)OR

Explain identification of protein coding regions. (15)

Discuss on drug discovery using bioinformatics tools. (15)OR

(a) Compare the gene structures in prokaryotes and eukaryotes. (7)(b) Explain molecular visualization. (8)

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