Bioengineering and Biotechnology Courses

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Contents

Biosignals and Systems ................................................3

Biomechanics ..............................................................7

Bio MEMS, NEMS, & Materials..................................10

Biomedical Imaging ..................................................14

Biophysics ..................................................................16

Biotechnology............................................................18

General Textbooks ....................................................22

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3

Biosignals and SystemsFrom Esteemed CRC Press Author Robert B. Northrop

University of Connecticut, Storrs, USA

For more information and complete contents, visit www.crctextbooks.com

Updated Edition of a Bestseller

Analysis and Application of Analog ElectronicCircuits to Biomedical InstrumentationSecond EditionSeries: Biomedical Engineering

Pedagogical Features

• An extensive glossary

• End-of-chapter problems and examples thatemphasize biomedical electronic applications

A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents

Sources and Properties of Biomedical SignalsProperties and Models of Semiconductor Devices

Used in Analog Electronic SystemsThe Differential AmplifierGeneral Properties of Electronic, Single-Loop

Feedback SystemsFeedback, Frequency Response, and Amplifier

StabilityOperational Amplifiers and ComparatorsIntroduction to Analog Active FiltersInstrumentation and Medical Isolation AmplifiersNoise and the Design of Low-Noise Signal

Conditioning Systems for BiomedicalApplications

Digital InterfacesModulation and Demodulation of Biomedical

SignalsPower Amplifiers and Their Applications in

BiomedicineWireless Patient MonitoringRFID Tags, GPS Tags, and Ultrasonic Tags Used in

Ecological ResearchExamples of Special Analog Circuits and Systems

Used in Biomedical InstrumentationAppendixGlossaryBibliography and Recommended Reading

Catalog no. K12982, March 2012, 578 pp.ISBN: 978-1-4398-6669-6, $119.95 / £76.99Also available as an eBook

Analysis and Application of Analog ElectronicCircuits to Biomedical Instrumentation, SecondEdition helps biomedical engineers understand thebasic analog electronic circuits used for signal con-ditioning in biomedical instruments. It explains thefunction and design of signal conditioning systemsusing analog ICs—the circuits that enable ECG, EEG,EMG, ERG, tomographic images, biochemical spec-trograms, and other crucial medical applications.

This book demonstrates how op amps are the key-stone of modern analog signal conditioning systemdesign and illustrates how they can be used to buildinstrumentation amplifiers, active filters, and manyother biomedical instrumentation systems and sub-systems. It introduces the mathematical tools usedto describe noise and its propagation through linearsystems, and it looks at how signal-to-noise ratioscan be improved by signal averaging and linear fil-tering.

• Analyzes the properties of photonic sensorsand emitters and the circuits that power them

• Details the design of instrumentation amplifiersand medical isolation amplifiers

• Considers the modulation and demodulationof biomedical signals

• Examines analog power amplifiers, includingpower op amps and class D (switched) PAs

• Describes wireless patient monitoring, including Wi-Fi and Bluetooth communicationprotocols

• Explores RFID, GPS, and ultrasonic tags andthe design of fractal antennas

• Addresses special analog electronic circuitsand systems such as phase-sensitive rectifiers,phase detectors, and IC thermometers

By explaining the "building blocks" of biomedicalsystems, the author illustrates the importance ofsignal conditioning systems in the devices thatgather and monitor patients’ critical medical infor-mation. Fully revised and updated, this second edi-tion includes new chapters, a glossary, and newend-of-chapter problems.



From Esteemed CRC Press Author Robert B. NorthropUniversity of Connecticut, Storrs, USA

4 Request your Complimentary eBook or Print Exam Copy at www.crctextbooks.com

Biosignals and Systems

Signals andSystems Analysisin BiomedicalEngineeringSecond EditionSeries: Biomedical Engineering

The interdisciplinary field ofbiomedical engineeringrequires its practitioners toknow and master not only engineering skills, butalso a diversity of material in the biological sciences.This text helps biomedical engineering studentsand professionals strengthen their skills in the net-work of applied mathematics that ties togetherthese diverse disciplines. Based on the author's 30years of experience in teaching as well as his per-sonal research on neurosensory systems, this book,now in its second edition, provides a ready sourceof information on the specialized mathematicaltechniques most useful in describing and analyzingbiomedical signals.

Features

• Focuses on the mathematical tools required toanalyze and describe the signals and systemsfound in biomedical engineering

• Includes a comprehensive chapter on jointtime-frequency analysis of nonstationary biomedical signals, and the use of wavelets in JTFA

• Explores the mathematics of tomographicimaging

• Describes the analytical signal and the Hilbert transform

• Discusses the analysis of nonlinear systems,nonlinear oscillators, and biological clocks

• Introduces the analysis of and modeling strategies for complex systems

A solutions manual is available upon qualifying course adoption.

Selected Contents

Introduction to Biomedical Signals and Systems.Review of Linear Systems Theory. The LaplaceTransform and Its Applications. Fourier SeriesAnalysis of Periodic Signals. The ContinuousFourier Transform. The Discrete Fourier Transform.Introduction to Joint Time Frequency Analysis ofBiomedical Signals. Introduction to the Analysis ofStationary Noise, and Signals Contaminated withNoise. ... Glossary. Appendices. Index.

Catalog no. K10633, March 2010, 654 pp.ISBN: 978-1-4398-1251-8, $109.95 / £69.99

Introduction toComplexity and ComplexSystemsWritten for students and pro-fessionals in the fields of bio-medical engineering, systems biology, biophysics,and physiology, this unique reference covers com-plexity issues within living systems. Topics includehuman responses to coping with complex systems,the Law of Unintended Consequences, the relationof complexity to evolution, the complexity inherentin invertebrate immune systems, and the complex-ity inherent in economic systems. A comprehensiveglossary provides acronyms and terms relating tocomplex, nonlinear biological systems. Dynamicmodels and homework questions are also includedto further aid in understanding.


• Dynamic models for various complex systems• Present-day examples for dealing with

complex systems• Homework problems• A glossary


Selected Contents

Introduction to Complexity and ComplexSystems. Introduction to Large Linear Systems.Introduction to Nonlinear Biochemical Systemsand Biochemical Oscillators. Modularity,Redundancy, Degeneracy, Pleiotropy andRobustness in Complex Biological Systems. TheEvolution of Biological Complexity; InvertebrateImmune Systems. The Complex Adaptive andInnate Human Immune Systems. Complexity inQuasispecies: MicroRNAs. Introduction toPhysiological Complexity: Examples of Models ofSome Complex Physiological Systems. The Questfor Quantitative Measures of Complexity."Irreducible and Specified Complexity" in LivingSystems. Introduction to Complexity in EconomicSystems. Dealing with Complexity. Appendix.Bibliography and References. Glossary. Index.

Catalog no. K11775, December 2010, 551 pp.ISBN: 978-1-4398-3901-0, $87.95 / £56.99Also available as an eBook




5



BiomedicalEngineeringPrinciplesSecond Edition

Arthur B. Ritter, Vikki Hazelwood, Antonio Valdevit, and Alfred N. Ascione

Praise for the Previous Edition

“... not only an in-breadth overview on currentBME fields, but also an in-depth analysis of specificselected topics that are supported by appropriatemathematical models, equations, quantitative datacharts and tables."

—Biomedical Engineering Online, 2005

“... an excellent textbook for a class. Each chaptercontains numerous examples and contains manyfigures to enhance learning. References and sugges-tions for further reading are included at the end ofeach chapter. Problems are included at the end ofchapters, where they will best test the student'sknowledge.”

—Richard C. Fries, PE, CRE, Baxter Healthcare, Inc., in IEEE Engineering in Medicine and Biology Magazine,

December 2006

Integrating engineering, medicine, biology, andphysics, this book clearly defines basic principles inimage processing and biomechanics, modeling phys-iological processes, and bioelectric signal analysis tobuild a solid understanding of devices and designs forimproved functioning of the human body.


• Extensive examples• In-chapter problems


Selected Contents

Introduction: Modeling of Physiological Processes.Cell Physiology and Transport. Principles andBiomedical Applications of Hemodynamics. ASystems Approach to Physiology. TheCardiovascular System. Biomedical SignalProcessing. Signal Acquisition and Processing.Techniques for Physiological Signal Processing.Examples of Physiological Signal Processing.Principles of Biomechanics. Practical Applicationsof Biomechanics. Biomaterials. Principles ofBiomedical Capstone Design. Unmet ClinicalNeeds. Entrepreneurship: Reasons why Most GoodDesigns Never Get to Market. ...

Catalog no. K10621, May 2011, 540 pp.ISBN: 978-1-4398-1232-7, $104.95 / £66.99Also available as an eBook

Bestseller

Basic TransportPhenomena inBiomedicalEngineeringThird Edition

Ronald L. FournierUniversity of Toledo, Ohio, USA

Exploring fundamental engineering and life scienceprinciples to uncover key concepts in biomedicalengineering transport phenomena, this volumebegins with a review of the basics of thermodynam-ics. It then examines the physical properties of bodyfluids and the cell membrane before moving on totopics such as properties of blood, solute transport,pharmacokinetic analysis, extracorporeal devices,tissue engineering, and bioartificial organs.Homework problems provide students the opportu-nity to explore in greater detail the material coveredin each chapter.

Features

• Provides an introductory-level text for studentsin bioengineering, chemical engineering,mechanical engineering, and the life sciences

• Presents a basic understanding and the theories of transport in biological systems andthen builds on this knowledge base to showreal-world applications in the developmentand design of artificial organs, drug deliverysystems, and tissue engineering

• Contains an extensive bibliography of theresearch literature that supports the material in the text


• Numerous examples with a discussion of thenumerical methods used to solve the problems

• Many illustrations• End-of-chapter homework problems


Selected Contents

Introduction. A Review of ThermodynamicConcepts. Physical Properties of the Body Fluidsand the Cell Membrane. The Physical and FlowProperties of Blood. Solute Transport in BiologicalSystems. Pharmacokinetic Analysis. ExtracorporealDevices. Tissue Engineering. Bioartificial Organs.Index.

Catalog no. K11304, August 2011, 483 pp.ISBN: 978-1-4398-2670-6, $93.95 / £46.99Also available as an eBook






Introduction toBiomedicalEngineeringTechnologySecond Edition

Laurence StreetRosedale, British Colombia, Canada

Thoroughly revised and updated, this second edi-tion describes current technological devices, thephysiological and anatomical basis of their func-tion, their practical applications, and their commonlocations in hospitals.

• Covers a wider range of devices and includesan expanded section on equipment management

• Describes the day-to-day work of biomedicalengineering technologists using extensiveexamples

• Provides appendices listing normal medicalvalues, biomedical associations, test equipmentmanufacturers, helpful Internet resources, andmore


• Chapter summaries• Questions to aid in reader comprehension• More than 360 illustrations • A 16-page grayscale insert with photographs

of real-life equipment problems


Selected Contents

Introduction. Diagnostic Devices: Part One.Diagnostic Devices: Part Two. Diagnostic Devices:Part Three. Diagnostic Imaging. TreatmentDevices: Part One. Treatment Devices: Part Two.Treatment Devices: Part Three. BiomedicalEngineering Technologist (BMET) Work. Testersand Tools. Batteries, Radiation, and Computers.Technology Management. Appendix A: NormalValues. Appendix B: Regulations and Standards.Appendix C: Biomedical Engineering TechnologyPrograms in the United States and Canada.Appendix D: Biomedical Associations. AppendixE: Devices and Manufacturers. Appendix F: TestEquipment Manufacturers. Appendix G:Bibliography and Internet Resources. Index.

Catalog no. K12781, October 2011, 391 pp.ISBN: 978-1-4398-6058-8, $93.95 / £59.99Also available as an eBook

Biology forEngineersArthur T. JohnsonUniversity of Maryland, College Park, USA

Introducing the field of biolo-gy to today’s engineeringstudents, this entry-level textminimizes unnecessarymemorization of connections and classificationsand emphasizes concepts, technology, and the uti-lization of living things. Filled with practical exam-ples, the book discusses biological responses fromthe perspectives of psychology, human factors,genetics, plant and animal physiology, imaging,control systems, actuary, and medicine. Offeringnumerous tables of useful information, it covers thescaling of biological responses and attributes as wellas different types of applications related to biologi-cal systems. Classroom-tested at the University ofMaryland, this comprehensive text introduces theconcepts and terminology needed to understandmore advanced biology literature.

Features

• Explores areas in physics, chemistry, mathematics, and engineering relating tobiology

• Examines the differences between biologicalengineering and biological science

• Includes a chapter on scaling relations showing how size effects other physical characteristics

• Surveys a broad range of application areas


• Questions at the end of each chapter to testcomprehension

• Practical examplesA solutions manual is available

upon qualifying course adoption.

Selected Contents

Introduction: Introduction. Principles from theSciences: Principles of Physics. Principles ofChemistry. Principles of Mathematics andEngineering Sciences. Principles of Biology.Responses of Living Systems: BiologicalResponses in Context. Scaling Factors: AllometricRelationships from Evolutionary Pressure. UtilizingLiving Systems: Systems Approach. Appendices.References. Index.

Catalog no. 77635, September 2010, 775 pp.ISBN: 978-1-4200-7763-6, $109.95 / £69.99Also available as an eBook




7

Biomechanics


Forthcoming

Fundamentals of BiomechanicsRonald L. HustonUniversity of Cincinnati, Ohio, USA

Biomechanics is a fundamental topic of study that employs the principles of mechanicsapplied to human systems and organs. This textbook provides a comprehensive surveyof this increasingly important subject. After a review of terminology, a summary of

Tissue BiomechanicsHard and Soft TissueBonesBone Cells and Microstructure...Kinematical Preliminaries: FundamentalEquationsPoints, Particles, and BodiesParticle, Position, and Reference FramesParticle Velocity...Kinematic Preliminaries: Inertia ForceConsiderationsApplied Forces and Inertia ForcesMass CenterEquivalent Inertia Force Systems...Human Body Inertia PropertiesSecond Moment Vectors, Moments, and Productsof InertiaInertia DyadicsSets of Particles...Kinematics of Human Body ModelsNotation, Degrees of Freedom, and CoordinatesAngular VelocitiesGeneralized CoordinatesPartial Angular Velocities...Kinetics of Human Body ModelsApplied (Active) and Inertia (Passive) ForcesGeneralized ForcesGeneralized Applied (Active) Forces on a HumanBody Model...Dynamics of Human Body ModelsKane's EquationsGeneralized Forces for a Human Body ModelDynamical Equations...Numerical MethodsGoverning EquationsNumerical Development of the GoverningEquations...Simulations and ApplicationsReview of Human Modeling for DynamicSimulationA Human Body in Free-Space: A "Spacewalk"A Simple Weight Lift...Appendix: Anthropometric Data Tables

Catalog no. K14776, May 2013, c. 512 pp.ISBN: 978-1-4665-1037-1, $99.95 / £63.99

human anatomy, and a presentation of anthropo-metric data, the text discusses methods for biome-chanical analyses including essential mathematics,mechanics, and modeling techniques. It then cov-ers tissue biomechanics, kinematics and dynamicsof human body models, and applications such aslifting, walking, swimming, and accident victimsimulation. Each chapter contains reference lists formore in-depth study and problems sets with solu-tions.


• An extensive glossary• Numerous examples, illustrations, and tables• End-of-chapter problems to test assimilation


Selected Contents

IntroductionPrincipal Areas of BiomechanicsApproach in This BookReview of Human Anatomy and Some BasicTerminologyGross (Whole-Body) ModelingPosition and Direction Terminology...Methods of Analysis I: Review of Vectors,Dyadics, Matrices, and DeterminantsVectorsVector Algebra: Addition and Multiplication byScalars...Methods of Analysis II: Forces and ForceSystemsForces: Vector RepresentationsMoments of ForcesMoments of Forces about Lines...Methods of Analysis III: Mechanics of MaterialsConcepts of StressConcepts of StrainPrincipal Values of Stress and Strains...Methods of Analysis IV: Modeling of BiosystemsMultibody (Lumped Mass) SystemsLower Body ArraysWhole Body, Head/Neck, and Hand ModelsGross-Motion Modeling of Flexible Systems...




Biomechanics

Biofluid MechanicsThe Human Circulation, Second Edition

Krishnan B. Chandran, Ajit P. Yoganathan, and Stanley E. Rittgers

“... the book provides a good platform in fluid mechanics prior to progressing tothe physiological applications which make it an appropriate textbook for BMEstudents."

—Professor Tim McGloughlin, Centre for Applied Biomedical Engineering Research andDepartment of Mechanical Aeronautical and Biomedical Engineering, University of Limerick

Cardiac Valves...BIOMECHANICS OF THE

HUMAN CIRCULATIONRheology of Blood and Vascular MechanicsRheology of BloodSummary...Static and Steady Flow ModelsIntroductionHydrostatics in the CirculationApplications of the Bernoulli EquationRigid Tube Flow Models...Unsteady Flow and Nonuniform

Geometric ModelsIntroductionWindkessel Models for the Human CirculationContinuum Models for Pulsatile Flow Dynamics...Native Heart ValvesIntroductionAortic and Pulmonary ValvesMitral and Tricuspid ValvesCARDIOVASCULAR IMPLANTS,

BIOMECHANICAL MEASUREMENTS, AND COMPUTATIONAL SIMULATIONS

Prosthetic Heart Valve DynamicsIntroductionBrief History of Heart Valve ProsthesesHemodynamic Assessment of Prosthetic Heart

Valves...Vascular Therapeutic TechniquesVascular Graft ImplantsArteriovenous FistulasTypes of Vascular Graft Materials Used...Fluid Dynamic Measurement TechniquesIntroductionBlood Pressure MeasurementBlood Flow MeasurementImpedance Measurement...Computational Fluid Dynamic Analysis

of the Human CirculationIntroductionComputational Fluid Dynamic (CFD) Analysis

Techniques ...Index

Catalog no. K12006, February 2012, 451 pp.ISBN: 978-1-4398-4516-5, $104.95 / £66.99Also available as an eBook

This classroom-tested text teaches students howfluid mechanics is applied to the study of the humancirculatory system. Reflecting changes in the fieldsince the publication of its predecessor, this secondedition includes improved figures, additional exam-ples, and more problems at the end of each chapter.It also presents a new chapter on the computationalfluid dynamic analysis of the human circulation,which reflects the rapidly increasing use of compu-tational simulations in research and clinical arenas.

• Provides a classroom-tested textbook for a firstcourse on fluid mechanics in human circulation,focusing on the heart and major arteries

• Reviews fluid and solid mechanics and normalcardiovascular physiology

• Explains how to model steady and unsteadyflows

• Evaluates the design and development of artificial heart valves, stent implants, and vascular grafts

• Describes various considerations and approachesinvolved in the computational modeling of cardiovascular diseases and therapies


• End-of-chapter problems• Examples• Numerous figures throughout, selected from

the publications of many eminent researchers


Selected Contents

FLUID AND SOLID MECHANICS AND CARDIOVASCULAR PHYSIOLOGY

Fundamentals of Fluid MechanicsIntroductionIntrinsic Fluid PropertiesHydrostatics...Introduction to Solid MechanicsIntroduction to Mechanics of MaterialsAnalysis of Thin-Walled Cylindrical Tubes...Cardiovascular PhysiologyIntroductionHeart



9

Biomechanics


Biomechanics ofthe Upper LimbsMechanics, Modelingand MusculoskeletalInjuries, Second Edition

Andris FreivaldsThe Pennsylvania State University,University Park, USA

Over the past two decades, the growth in comput-er-related jobs has led to considerable increase inthe number of work-related musculoskeletal disor-ders in the upper limbs. Biomechanics of theUpper Limbs: Mechanics, Modeling andMusculoskeletal Injuries, Second Edition offersvital information and tools to improve analysis ofexternal forces and their effects on the humanbody. This can help ergonomists better understandjob stressors and the role they play in the develop-ment of disorders, enabling them to modify thework environment and educate practitioners to bet-ter control harmful situations. Now in its secondedition, this comprehensive text is expanded toinclude recent findings regarding job stressors anda variety of ergonomic solutions. It providesresearch on the biomechanics of the upper limbsand the mechanics of neuromuscular systems. Thebook also covers risk factors for various disordersand tools used to identify their causes.


• Numerous examples in each chapter

• Downloadable PowerPoint® slides, sampleexams, and other background material on a supporting website

• End-of-chapter references to enhance further study


Selected Contents

Introduction to Biomechanics. Structure of theMusculoskeletal System. NeuromuscularPhysiology and Motor Control. Modeling ofMuscle Mechanics. Models of the Upper Limbs.Musculoskeletal Disorders and Risk Factors.Instrumentation. Job and Worksite Analysis. Hand Tools. The Office Environment.

Catalog no. 91190, February 2011, 564 pp.ISBN: 978-1-4200-9119-9, $125.95 / £79.99Also available as an eBook

BiofluidDynamicsPrinciples andSelected Applications

Clement KleinstreuerNorth Carolina State University,Raleigh, USA

Biofluid Dynamics builds a solid understanding ofmedical implants and devices from a bioengineer-ing standpoint. The text features worked examplesand mathematical appendices; exercises and proj-ect assignments to stimulate critical thinking andbuild problem-solving skills; numerous illustrations,including a 16-page color insert; computer simula-tions of biofluid dynamics processes and medicaldevice operations; tools for solving basic biofluidproblems; and a glossary. The text can be used asa primary selection for a comprehensive course orfor a two-course sequence or as a reference for pro-fessionals.


Catalog no. 2221, April 2006, 528 pp.ISBN: 978-0-8493-2221-1, $119.95 / £77.99

Biomechanicsand ExercisePhysiologyQuantitativeModeling

Arthur T. JohnsonUniversity of Maryland, College Park, USA

Using numerous worked examples to demonstratewhat and when to calculate, this text covers morethan just the fundamentals of exercise physiology,it demonstrates the vast amount of physiologicalmaterial that can be quantitatively predicted anddescribes how to translate this information intoapplications. The book examines the energetics ofexercise, biomechanics, circulation, respiration,and thermoregulation, and includes numericalexamples and homework problems. With anemphasis on quantitative description, it includestables and illustrations that make this book helpfulfor estimating magnitudes, determining trends,and illustrating concepts.

Catalog no. DK5813, March 2007, 688 pp.ISBN: 978-1-57444-906-8, $145.95 / £93.00






Bio MEMS, NEMS & Materials

Textbooks for Your Biomaterials Lectures and Lab Courses

An Introductionto BiomaterialsSecond EditionEdited by

Jeffrey O. HollingerCarnegie Mellon University,Pittsburgh, Pennsylvania, USA

Series: Biomedical Engineering

The second edition of this popular text includesnine new chapters that provide a comprehensiveand up-to-date educational framework for biomate-rials education. A new chapter on the biology ofwound healing sets the stage for the basic require-ments of standardized biomaterials testing andexplains the reactions between biomaterials andthe living system into which it is implanted.

Features

• Covers wound healing biology and hostresponse to implanted biomaterials

• Examines the regulatory process, includingstandardized product testing

• Reviews the innovativeness of biomaterials,with inventorship and patents in mind

• Considers experimental design, basic scientificmethods, and statistics


• Numerous examples• End-of-chapter questions and answers• Extensive references for further study

An instructor's manual and figure slides are available upon qualifying course adoption.

Selected ContentsConsensus Definitions, Fundamental Concepts,and a Standardized Approach to AppliedBiomaterials Sciences. Biology, Biomechanics,Biomaterial Interactions: Wound Healing Biology.Biology, Biomechanics, Biomaterial Interactions:Cellular Mechanics. Biology, Biomechanics,Biomaterial Interactions: Materials–HostInteractions. Biomaterials Testing, Statistics,Regulatory Considerations, Intellectual Property:Standardized Materials Testing. BiomaterialsTesting, Statistics, Regulatory Considerations,Intellectual Property: Statistics. BiomaterialsCompositions. Biomaterials Applications. Index

Catalog no. K10637, November 2011, 644 pp.ISBN: 978-1-4398-1256-3, $119.95 / £49.99Also available as an eBook

A LaboratoryCourse inBiomaterialsWujing XianUniversity of Illinois at Urbana-Champaign, USA

A teaching tool for instructorsin biomaterials and bioengi-neering, this volume is a com-prehensive laboratory textbook. It trains readers inlaboratory skills, data analysis, problem solving, andscientific writing. It integrates a variety of principlesthat include materials science, chemistry, biochem-istry, molecular and cell biology, and engineering.Providing detailed descriptions, explanations, andillustrations of experiments, the text also includes aseries of questions and answers at the end of eachchapter to clarify concepts. Many of the experi-ments presented are adapted from research papersto reflect the recent progress in biomaterials andbioengineering.


• Detailed, step-by-step descriptions of lab procedures and explanations for the underlyingprinciples

• User-friendly graphic illustrations for theexperiments

• End-of-chapter questions and answers to clarify concepts and induce critical thinking

• Text boxes with in-depth information, casestudies, and lab tips

• Information on equipment, reagents, and supplies for instructors

Selected Contents

Basic Laboratory SkillsModule I: Drug Delivery: Controlled Release ofEncapsulated Protein from PLGA MicrospheresModule II: Natural Biomaterials: Collagen andChitosanBasic Laboratory Skills II: Cell Culture andMicroscopyModule III: Biocompatibility Testing: Cytotoxicityand AdhesionModule IV: Tissue Engineering: OrganotypicCultures of Skin EquivalentsModule V: Bioceramics: Porous HydroxyapatiteCompositeAppendix: AnswersIndex

Catalog no. 75829, June 2009, 216 pp., Soft CoverISBN: 978-1-4200-7582-3, $67.95 / £43.99




11



A LaboratoryCourse in TissueEngineeringMelissa Kurtis Micou and Dawn M. Kilkenny

“The book is well organized to teach cell cultureand tissue engineering experiments to novice andexperienced students. There is a quantitativeemphasis in the book that strengthens the ‘engineering’ part of tissue engineering.”

—Ann Saterbak, Rice University, Houston, Texas, USA

“This book has a protocol-like style and can actu-ally be used directly by teachers to prepare labcourses as well as by people with lab experiencethat enter the field of tissue engineering. … pro-vides students with good insight in methods, tech-niques and approaches in the field of tissue engi-neering."

—Gerjo J.V.M. van Osch, Erasmus MC, UniversityMedical Center Rotterdam, The Netherlands

“… a much-needed book for undergraduate bio-engineering curricula. Tissue engineering is a topicbest learned through practice, and this book justmight take the fear out of offering a laboratorycourse on the subject."

—Michael J. Moore, Ph.D., Tulane University, New Orleans, USA

“… provides comprehensive coverage of laboratorytechniques in tissue engineering, including detailedexperimental protocols."—Adam Higgins, Oregon State University, Corvallis, USA

A hands-on lab manual for tissue engineeringinstruction, this book contains 15 standalone exper-iments based on both classic and modern approach-es. Experiments encompass a set of widely applica-ble techniques: cell culture, microscopy, histology,immunohistochemistry, mechanical testing, softlithography, and common biochemical assays.


• Fifteen standalone experiments, allowing youto customize your courses

• Prelab and postlab questions for each experiment• More than 70 illustrations


Catalog no. K13694, August 2012, 304 pp.Soft Cover, ISBN: 978-1-4398-7893-4$59.95 / £38.99Also available as an eBook

Introduction toBioMEMSAlbert FolchUniversity of Washington, Seattle, USA

“The field has been waitingfor a true textbook that pro-vides a practical, historical,authoritative and compre-hensive introduction to bioMEMS. It has finallyarrived, courtesy of Albert Folch, complete withPowerPoint lectures and thoughtful homeworkquestions.”

—David J. Beebe, University of Wisconsin–Madison

“... successfully integrates microfabrication and thephysics of microfluidics with numerous biologicalapplications. It provides a visual feast of imagesthat lead to a comprehensive understanding ofmany complex concepts. Applications presentedrange from biomolecules to cells, tissues, andorganisms, and are presented in clear, logicalsteps. It serves as an outstanding text for advancedundergraduates and graduate students ...”

—Dr. Fawwaz Habbal, Harvard University

“With extensive citations of the current literature,explanations that really put the technology in con-text, clear enunciation of the motivations forminiaturization, and historical perspective, theauthor has made the material very accessible andclear … . I definitely recommend this textbook forbioengineering students.”

—Professor Karen C. Cheung, University of British Columbia

“... a monumental achievement which brings anauthoritative and comprehensive account to the rapidly growing, multidisciplinary field of bioMEMS.”

—Mehmet Toner, Helen Andrus Benedict Professor ofBioengineering, Harvard Medical School, USA

This classroom-tested book—in color throughout—covers the whole breadth of this dynamic field,including classical microfabrication, microfluidics,tissue engineering, cell-based and noncell-baseddevices, and implantable systems.


• Fundamental concepts highlighted anddefined in an extensive glossary

• More than 400 color figures, problem sets,design challenges, and key references

• Downloadable PowerPoint® slides for instructors

An instructor's manual is available upon qualifying course adoption.







From MEMS toBio-MEMS andBio-NEMSManufacturingTechniques andApplications

Marc J. MadouUniversity of California, Irvine, USA

This textbook details manufacturing techniquesapplicable to bio-nanotechnology. After reviewingMEMS techniques, materials, and modeling, theauthor covers nanofabrication, genetically engi-neered proteins, artificial cells, nanochemistry, andself-assembly.

Features

• Focuses on applications of NEMS and MEMS

• Covers scaling laws, actuators, and fluidics

• Discusses top-down and bottom-upmanufacturing methods

• Explains how to use nature as a guide


• End-of-chapter problems

• Worked-out problems within the text

• Color illustrations throughout

• Extensive references for further reading

• A comprehensive glossary of termsA solutions manual, PowerPoint® lecture slides, and electronic

figures are available upon qualifying course adoption.

Selected Contents

From Traditional Manufacturing ToNanotechnology: Nonlithography-Based(Traditional) and Lithography-Based(Nontraditional) Manufacturing Compared.Nature as an Engineering Guide: Biomimetics.Nanotechnology: Top-Down and Bottom-UpManufacturing Approaches Compared.Packaging, Assembly, and Self-Assembly. SelectedMaterials and Processes for MEMS and NEMS.Metrology and MEMS/NEMS Modeling. Scaling Laws, Actuators, and Power and BrainsIn Miniature Devices: Scaling Laws. Actuators.Power and Brains in Miniature Devices. Miniaturization Application: MEMS and NEMSApplications.

Catalog no. 5516X, June 2011, 650 pp.ISBN: 978-1-4200-5516-0, $104.95 / £66.99Also available as an eBook

BioMEMSScience andEngineeringPerspectives

Simona Badilescu and MuthukumaranPackirisamyConcordia University, Montreal, Quebec, Canada

BioMEMS: Science and Engineering Perspectivessupports and expedites the multidisciplinary learn-ing involved in the development of biomicrosys-tems. Divided into nine chapters, it starts with a bal-anced introduction of biological, engineering,application, and commercialization aspects of thefield.

The book also discusses:

• Different materials and platforms used todevelop biomicrosystems

• Various biological entities and pathogens (in ascending order of complexity)

• The multidisciplinary aspects of engineeringbioactive surfaces

• Engineering perspectives, including methodsof manufacturing bioactive surfaces anddevices

• Microfluidics modeling and experimentation

• Device level implementation of BioMEMS concepts for different applications


• Examples and problems

• Review questions

• Case studies


Selected Contents

Introduction. Substrate Materials Used inBioMEMS Devices. Biomolecules and ComplexBiological Entities: Structure and Properties.Engineering of Bioactive Surfaces. Methods ofStudy and Characterization of Surface-ModifiedSubstrates. Biosensing Fundamentals. Fabricationof BioMEMS Devices. Introduction toMicrofluidics. BioMEMS: Life Science Applications.

Catalog no. K10877, April 2011, 368 pp.ISBN: 978-1-4398-1699-8, $104.95 / £66.99Also available as an eBook




13



BiomedicalMicrosystemsEllis MengUniversity of Southern California,Los Angeles, USA

Written by an activeresearcher named one ofTechnology Review’s Young Innovators Under 35, thisbook begins with an introduction to the benefits ofminiaturization. It introduces materials, fabricationtechnology, and the necessary components of allBioMEMS. The author covers fundamental princi-ples and building blocks, including microfluidicconcepts, lab-on-a-chip systems, and sensing anddetection methods. The final chapters explore sev-eral important applications of BioMEMS, such asmicrodialysis, catheter-based sensors, MEMSimplants, neural probes, and tissue engineering.Detailed examples, exercises, and illustrations helpclarify the concepts.



BiomaterialsA Nano Approach

Seeram Ramakrishna,Murugan Ramalingam,T.S. Sampath Kumar, andWinston O. Soboyejo

From a multidisciplinary pointof view, this book examines basic concepts, pro-cessing methodologies, and techniques involved inthe preparation and characterization of nanobio-materials that are specific to biomedical applica-tions. It spans their historical development andreviews recent advances in the field. It describeshow basic concepts in nanotechnology are appliedto the processing of novel nanobiomaterials, includ-ing nanostructured metals and alloys. Presentingillustrative examples and applications, this textoffers a solid framework for understanding presentand future trends of biomaterials in human healthcare systems.

Figure slides are available upon qualifying course adoption.

Catalog no. 47817, June 2010, 372 pp.ISBN: 978-1-4200-4781-3, $104.95 / £73.99

UnderstandingNanomedicineAn IntroductoryTextbook

Rob BurgessMedical NanotechnologiesIncorporated, Richardson, Texas, USA

"Dr. Burgess has done anexcellent job in providing themuch-needed background in the numerous physi-cal, chemical, and biological methods that areused to enable nanomedicine. This book will be auseful reference for any student in the field ofnanomedicine and describes many examples wherenanotechnology promises to improve the diagnosis,monitoring, and treatment of disease”

—Dr. Gareth Hughes, Medical Nanotechnologies, Inc., USA

This book comprehensively covers a broad range oftherapeutic and diagnostic applications of nan-otechnology, providing descriptions of cutting-edge discoveries along with historical perspectives.

Catalog no. N10477, June 2012, 524 pp.ISBN: 978-981-4316-38-5, $149.95 / £95.00Also available as an eBook

BestsellerDesign ofBiomedicalDevices andSystemsSecond EditionPaul H. King and Richard C. Fries

The second edition of a bestseller, this book pro-vides a comprehensive overview of biomedicaldevice and system design—including topics relatedto databases, process analysis, and device improve-ment—from a strong design perspective. It coversall aspects of design that must be considered forcomplex biomedical projects. This second editionfeatures information on device definition and relia-bility, as well as testing and hardware verification,and each chapter has been updated to reflectadvances in the field.


Catalog no. 61798, August 2008, 424 pp.ISBN: 978-1-4200-6179-6, $129.95 / £82.99Also available as an eBook







Biomedical Imaging

Webb's Physicsof MedicalImagingSecond EditionEdited by

M.A. FlowerInstitute of Cancer Research/RoyalMarsden NHS Foundation Trust, UK

Series in Medical Physics andBiomedical Engineering

“Possibly the most comprehensive book on the subject currently on the market.”

—Dr. Sandro Olivo, University College London

Praise for the First Edition

“Steve Webb has produced a first-class book.Because The Physics of Medical Imaging is up todate in a rapidly changing field, it is the text ofchoice for teaching graduate research students inthis new and exciting subspeciality of physics.”

—Physics Today

“… a worthwhile addition to the personal libraryof anyone connected with this field.”—Journal of Clinical Physics and Physiological Measurement

“For all those requiring a comprehensive review ofmedical imaging techniques, at a fairly basic level,this text is highly recommended.”

—Australian Physicist

“This is a book well worth the money and I canstrongly recommend it both as desk and bedsidereading.”

—HPA Bulletin

“Developments in digital radiography, together withan analysis of the computing requirements of thevarious techniques, complete this excellent text. Theauthors have done a remarkable job in coveringsuch a wide subject so well in such a short book.”

—Image Processing Magazine

Selected Contents

In the Beginning: The Origins of MedicalImaging. Diagnostic Radiology with X-Rays. X-RayTransmission Computed Tomography. ClinicalApplications of X-Ray Computed Tomography inRadiotherapy Planning. Radioisotope Imaging.Diagnostic Ultrasound. Spatially LocalisedMagnetic Resonance. Physical Aspects of InfraredImaging. Imaging of Tissue Electrical Impedance.Optical Imaging. Mathematics of ImageFormation and Image Processing. Medical ImageProcessing. Perception and Interpretation ofImages. Computer Requirements of ImagingSystems. Multimodality Imaging. Epilogue. Index.

Catalog no. IP743, June 2012, 864 pp.ISBN: 978-0-7503-0573-0, $89.95 / £49.99Also available as an eBook

BiomedicalSignal andImageProcessingSecond Edition

Kayvan Najarian and Robert Splinter

“... a great collection of topics ... highly recommended ..."

—Purang Abolmaesumi, University of British Columbia,Vancouver, Canada

“... balances the coverage of physics of biomedicalimaging with biomedical image processing. … Iwas impressed by how clearly the concepts areexplained."

—Shahram Shirani, McMaster University,Hamilton, Ontario, Canada

“… an excellent bridge between the physiologicalsignificance of the methods, and the underlyingmathematics. … covers a broad range of biomed-ical problems. … clear, well written, and easy tofollow. … this is an excellent course textbook, andalso an excellent reference book for professionals."

—Dr. Kristian Sandberg, Computational Solutions, Inc.,Boulder, Colorado, USA


• Numerous examples, many of which are MATLAB® based

• End-of-chapter problems• Downloadable figures for presentations

A solutions manual is availableupon qualifying course adoption.

Selected Contents

Introduction To Digital Signal And ImageProcessing: Signals and Biomedical SignalProcessing. Fourier Transform. Image Filtering,Enhancement, and Restoration. Edge Detectionand Segmentation of Images. Wavelet Transform.Other Signal and Image Processing Methods.Clustering and Classification. Processing OfBiomedical Signals: Electrical Activities of Cell.Electrocardiogram. Electroencephalogram.Electromyogram. Other Biomedical Signals.Processing Of Biomedical Images: Principles ofComputed Tomography. X-Ray Imaging andComputed Tomography. Magnetic ResonanceImaging. Ultrasound Imaging. Positron EmissionTomography. Other Biomedical ImagingTechniques. Related Titles.





15

Biomedical Imaging


Forthcoming

PracticalUltrasoundAn Illustrated Guide,Second Edition

Jane Alty, Edward Hoey,Michael Weston, andStephen Wolstenhulme

Practical Ultrasound contains everything you needto know to become competent in learning the skillsof ultrasound scanning. This essential illustratedguide will enable you to use the equipment andinterpret the images on screen accurately. It usesillustrations, accurate images, and uncomplicatedlanguage throughout to ensure that this guide ispractical and easy to use. In addition, it includesstep-by-step sections on how to perform ultrasoundscans, which are supplemented by high-qualityimages and handy hints.

Catalog no. K17225, March 2013, c. 282 pp.Soft Cover, ISBN: 978-1-4441-6829-7$79.95 / £49.99

Forthcoming

Introduction to Nuclear ScienceSecond Edition

Jeff C. BryanUniversity of Wisconsin,La Crosse, USA

This introductory text covers general aspects ofnuclear chemistry and physics. It discusses hownuclear science impacts our daily lives throughmedicine, electrical power generation, food safety,waste, and weapons. This edition features newchapters that address nuclear reactors, dosimetry,radiochemistry, and nuclear forensics. It alsoexpands coverage of nuclear medicine and radia-tion therapy. With additional end-of-chapter prob-lems, the text supplies critical information for stu-dents earning nuclear-related degrees, as well asproviding an accessible reference for anyone withan interest in nuclear issues.

A solutions manual is availableupon qualifying course adoption.

Catalog no. K14329, March 2013, c. 416 pp.ISBN: 978-1-4398-9892-5, $89.95 / £57.99Also available as an eBook

Applied Medical ImageProcessingA Basic Course

Wolfgang BirkfellnerMedical University of Vienna,Austria

“The topics covered are clearly explained, includingexplanations of the mathematical operations thatare required, therefore making it an ideal text foranyone who is new to medical image processing.”

—Sarah Cade, Scope, December 2011

“The CD adds substantial value … Several bookson image processing have been published recently,and this book takes a backseat to none of them. …Students who take a course where this book is usedas the course text will be fortunate indeed.”—William Hendee, Medical Physics, Vol. 37, December 2010

“... an outstanding work that will be of interest tovirtually all biomedical engineers. ... important concepts and definitions are described concisely andwell. ... a well-written, coherent, and comprehensivework covering the major topics in the field ...”

—Edward J. Ciaccio, Columbia University, BioMedical Engineering OnLine, 2011

“... a lucid, well-written, and hands-on textbookthat explains in simple terms and with examplesthe basic issues of medical image processing.”

—Prof. Leo Joskowicz, The Hebrew University of Jerusalem

“The plethora of examples in each chapter …allows the reader to apply the theory and visuallyassess the outcomes. ... a perfect blend of theoryand practice. I highly recommend it.”—Dr. Pascal Fallavollita, Technische Universität München


• Numerous diagrams and figures• Many practical examples for MATLAB® and

Octave with a CD featuring image materialand program files

Selected Contents

A Few Basics of Medical Image Sources. ImageRepresentation. Operations in Intensity Space.Segmentation. Filtering and Transformations.Spatial Transforms. Rendering, Visualization, andSurface Models. Registration. VolumeReconstruction. Appendix. Glossary. Index.

Catalog no. K11176, September 2010, 403 pp.ISBN: 978-1-4398-2444-3, $76.95 / £48.99Also available as an eBook






Biophysics

Ultrasonic andElectromagneticNDE forStructure andMaterialCharacterizationEngineering andBiomedical ApplicationsEdited by

Tribikram KunduThe University of Arizona, Tucson, USA

“... an essential reference for researchers and grad-uate students working in ultrasonic or electromag-netic NDE. The different chapters contributed byrecognized experts in the field cover both funda-mental theory as well as current research areas.”

—Dr. Paul Fromme, University College London, UK

“... provides a comprehensive and rigorousapproach of the fundamentals of linear and non-linear ultrasonics and electromagnetic methods ...also provides enough advanced engineering andbiological applications to make the reader familiarwith these technologies ... an excellent text for asenior/first-year graduate course in nondestructivetesting and evaluation, or as a text in a course inengineering and biological materials characteriza-tion. It is also an excellent reference book for prac-ticing engineers and scientists, and I highly recom-mend it.”

—Henrique Reis, University of Illinois at Urbana-Champaign, USA


• Questions, problems, and worked-out examples• More than 640 illustrations


Selected Contents

Mechanics of Elastic Waves and UltrasonicNondestructive Evaluation. Modeling of UltrasonicFields by Distributed Point Source Method.Electromagnetic Nondestructive Evaluation.Distributed Point Source Method for Imaging inElectrostatic and Electromagnetic Problems. GuidedWaves for Plate and Pipe Inspection. Fundamentalsand Applications of Nonlinear UltrasonicNondestructive Evaluation. Theory and Applicationsof Laser Ultrasonic Techniques. MaterialCharacterization by Nonlinear Ultrasonic Technique.Toward Structural Health Monitoring Solutions forBolted Joints. Measurement of the Elastic Propertiesof Solids by Brillouin Spectroscopy. ...

Catalog no. K11655, June 2012, 890 pp.ISBN: 978-1-4398-3663-7, $149.95 / £95.00Also available as an eBook

QuantitativeUnderstandingof BiosystemsAn Introduction to Biophysics

Thomas M. NordlundUniversity of Alabama atBirmingham, USA

“… highly recommended forintroducing biophysics to the motivated and curious undergraduate students.”

—Nikolaos Kourkoumelis, Contemporary Physics, June 2012

“This terrific text offers a broad range of learningopportunities for many undergraduate majors. … Itwill enable students to understand the significanceof biological parameters through quantitativeexamples—a modern way of learning biophysics.”

—American Journal of Physics, February 2012

“... a beautiful review of essential physics for under-standing biological systems ... emphasizing thatwhich is rarely taught in standard physics classes:how to think like a physicist.”

—Ernest Barreto, George Mason University


Catalog no. 89772, March 2011, 583 pp.ISBN: 978-1-4200-8972-1, $93.95 / £59.99

Also available as an eBook

New

PhysicalChemistry forEngineering andApplied SciencesFrank R. Foulkes

This book is the result of morethan 30 years of teaching by the author of a one-semester course in physical chemistry to first-year stu-dents at the University of Toronto. The enrollment var-ied from 300 to 800 students per year over the years.The book is unique in that it provides the detaileddevelopment of the equations, which can be followedrelatively easily even with only moderate mathemati-cal skills and backgrounds. The book provides interest-ing and inspiring examples, as well as many problemsand solutions.


Catalog no. K15157, September 2012, 703 pp.ISBN: 978-1-4665-1846-9, $89.95 / £57.99Also available as an eBook





17

Biophysics


New

MolecularMotors inBionano-technologyKeith Firman and James YouellUniversity of Portsmouth, UK

Many techniques have evolved to study and char-acterize molecular motors at the single-moleculelevel, such as the use of molecular tweezer devicesfor single-molecule studies. This book describes awide range of molecular motors, from chemical tobiological. It introduces readers to the concepts andbenefits of each technique and looks at structuralinformation and how this helps to understand func-tion. The book also examines how some of thesemotors are being used or may be used in the futureas part of a synthetic biology approach to buildingdevices and sensors.

Catalog no. N10568, November 2012, 300 pp.ISBN: 978-981-4267-02-1, $149.95 / £95.00Also available as an eBook

Dynamics ofBiologicalSystemsMichael SmallHong Kong Polytechnic University

Series: Chapman & Hall/CRCMathematical & Computational Biology

With exercises and projects in each chapter, thisclassroom-tested text shows how to apply a varietyof mathematical and computational techniques tomodel and analyze the temporal and spatial phe-nomena of biological systems. The mathematicalmodels and computer simulations offer insight intocardiac pacemakers, artificial electrical defibrillation,pandemics, pattern formation, flocking behavior,the interaction of autonomous agents, and hierar-chical and structured network topologies. MATLAB®

implementations of algorithms and case studies areavailable on the author’s website.



Physics forDiagnosticRadiologyThird Edition

Philip Palin DendyAddenbrookes NHS Trust,Cambridge, UK

Brian HeatonAberdeen Radiation ProtectionServices, UK

“This is the third edition of a well-established andpopular textbook on physics of diagnostic radiolo-gy. It is a textbook written in a clear and concisestyle, supported by excellent illustrations. The text-book describes recent state-of-the-art advances inmedical imaging in a way radiologists, radiogra-phers and medical physicists will find easy tounderstand. It is internationally recognised as oneof the key textbooks in its field.”

—Dr. Keith Faulkner, North East Strategic Health Authority, UK

Fully revised and updated, this bestselling text helpsreaders understand how various imaging tech-niques work.

Catalog no. 83155, August 2011, 720 pp.ISBN: 978-1-4200-8315-6, $79.95 / £49.99Also available as an eBook

Physiology,Biophysics, andBiomedicalEngineeringEdited by

Andrew W. WoodSwinburne University of Technology,Hawthorn, Victoria, Australia

Showing how biophysics and biomedical engineer-ing have advanced modern medicine, this text pro-vides a multidisciplinary understanding of biologicalphenomena and the instrumentation for monitoringthese phenomena. It also explores the application ofphysics and engineering methods to medicine andbiology. The book includes a range of numericalproblems with worked solutions and offers MATLAB®

code for advanced mathematical analysis of physio-logical and clinical monitoring systems.


Catalog no. C6513, February 2012, 782 pp. ISBN: 978-1-4200-6513-8, $99.95 / £49.99Also available as an eBook







Biotechnology

New

Learning Bio-Micro-NanotechnologyMel I. MendelsonLoyola Marymount University, Los Angeles, California, USA

"… a great combination of two key disciplines in the coming quarter of this century,biotechnology and nanotechnology. This will be a good guidebook for the academicadventure as well as a bible for the pioneer in the engineering and scientific field."

—Hideyuki Kanematsu, Suzuka National College of Technology

"… provides an excellent, multi-dimensionalapproach to learning that I have not seen in othernanotechnology text books. … I really like the multitude of ways the author has the studentsthink about the material through problems, groupactivities, thinking exercises, etc."

—Kory Goldammer, Richland College

Learning Bio-Micro-Nanotechnology is a primeron micro/nanotechnology that teaches the vocab-ulary, fundamental concepts, and applications ofmicro/nanotechnology in biology, chemistry,physics, engineering, electronics, computers, bio-medicine, microscopy, ethics, and risks tohumankind. It provides an introduction into thesmall world with a low fog index, emphasizing theconcepts using analogies and illustrations to simpli-fy the non-observables.

Features

• Introduces the micro/nanotechnology vocabulary, concepts, and applications fromfirst principles

• Breaks down the barriers between biology,chemistry, physics, engineering, and ethicswith cross-disciplinary coverage

• Includes biology, chemistry, physics,engineering, microscopy, electronics and

computers, and micro-technology• Discusses nanotechnology and cancer, risks,

ethics, and future predictions


• Case studies, thinking exercises, and analogies• Study questions using Bloom’s taxonomy,

team assignments, and assessment exercises• A math review and glossary of terms in the

appendix


Selected Contents

Thinking Small and BigIntroduction. Bit of Technology History. Tera-to-Pico Multipliers. Size of Things. What Is "SmallTechnology?". ...

Biomolecules and CellsIntroduction. Science of Evolution. Powers of "10"Revisited. Building a Human Cell. Biomolecules.Protein Folding. Identifying Biomolecules. ...Molecular ChemistryIntroduction. Periodic Table. Some ChemicalDefinitions. Chemical Bonding. Macromolecules.Polymer Examples. Colloids. Solid Nanomolecules.Bit of PhysicsIntroduction. Size Matters. Working toward theBottom. Definitions at the Bottom. ...Engineering Bits and BytesIntroduction. Electronics-on-a-Chip. ComputerApplications. Control Systems.Seeing Small ThingsIntroduction. Human Eye. Some MicroscopeDefinitions. Light Microscopes. ElectronMicroscopes.NanoelectronicsIntroduction. Computer Applications.Lithographic Tools. Recent Chip Developments.Emerging Technology. Bottom-Up Technology.Microelectromechanical SystemsIntroduction. Overview. Microsensors.Microactuators. Biochips.Nanotechnology and CancerIntroduction. What Is Cancer? Discovery: L.Detection: I. Delivery: T. Destruction: R.Risks: Nano or Mega?Introduction. Bit of Anatomy. Definitions Relatingto Risk. Chemical and Physical Factors. Benefitsversus Risks. Risk Assessment. Risk Management.Ethics and Social RelevanceIntroduction. Some Ethics Definitions. ...Self-Assembled FutureIntroduction. Definition: Self-Assembled Future.Geometric Proportions. Chemical Assembly. SnowFlake Assembly. Self-Assembled Colloids. ...AppendicesMath Review: Multiplying and DividingExponents. Math Review: Dimensional Analysis.Math Review: No. of Ways and Probability. ...

Chapters include key concepts, questions and problems, and references.

Catalog no. 82035, January 2013, 611 pp.ISBN: 978-1-4200-8203-6, $89.95 / £57.99Also available as an eBook



19

Biotechnology


New

Introduction to Instrumentation in Life SciencesPrakash Singh BisenDefense Research & Development Establishment, Gwalior, India

Anjana SharmaRani Durgavati University, Jabalpur, India

"A comprehensive text book on instrumentationmethods which covers all major topics includingpractical exercises representing the syllabi of vari-ous postgraduate and undergraduate programmesin life sciences."—Prof. Vinay Sharma, Professor and Head, Department ofBioscience and Biotechnology, Banasthali University, India

"I find that the book should be much useful forundergraduate (bachelor’s degree) and graduate(master’s degree) students. Very good book, proper-ly arranged topics, will certainly be useful for theaudience."—Anil Kumar, Ph.D., Professor and Head (Chair), School

of Biotechnology, Devi Ahilya University, India

Features

• Provides a comprehensive, detailed overviewof techniques and usage of key instrumenta-tion needed in biotechnology and life sciences

• Includes basic theoretical and practical detailsfor numerous types of chromatography, suchas column, thin-layer, and high-performanceliquid chromatography

• Describes a broad range of spectroscopic techniques, including UV/visible, fluorescence,NMR, and circular dichroism spectroscopy

• Covers electrophoretic techniques and theirapplications for deciphering the molecularnature of cell components as well as in genetechnology

• Contains unique in-depth coverage of fermentation processes

• Offers an excellent bench manual for researchers

Figure slides are available upon qualifying course adoption.

Selected Contents

Microscopy. Micrometry. ElectrochemicalTechniques. Chromatography. Spectroscopy.Centrifugation. Electrophoresis. X-RayMicroanalysis. Techniques with Radioisotopes.Fermentation. Conductivity Meters. Glossary.Index.

Catalog no. K14893, September 2012, 383 pp.Soft Cover, ISBN: 978-1-4665-1240-5$79.95 / £49.99Also available as an eBook

Instrumentation is central to the study of physiolo-gy and genetics in living organisms, especially atthe molecular level. Numerous techniques havebeen developed to address this in various biologicaldisciplines, creating a need to understand the phys-ical principles involved in the operation of researchinstruments and the parameters required in usingthem. Introduction to Instrumentation in LifeSciences fills this need by addressing differentaspects of tools that hold the keys to cutting-edgeresearch and innovative applications, from basictechniques to advanced instrumentation. The textdescribes all topics so even beginners can easilyunderstand the theoretical and practical aspects.

Comprehensive chapters encompass well-definedmethodology that describes the instruments andtheir corresponding applications in different scien-tific fields. The book covers optical and electronmicroscopy; micrometry, especially in microbial tax-onomy; pH meters and oxygen electrodes; chro-matography for separation and purification of prod-ucts from complex mixtures; spectroscopic andspectrophotometric techniques to determine struc-ture and function of biomolecules; preparative andanalytical centrifugation; electrophoretic tech-niques; and much more.

The book is designed to serve a wide range of stu-dents and researchers in diversified fields of life sci-ences: pharmacy, biotechnology, microbiology,biochemistry, and environmental sciences. It intro-duces different aspects of basic experimental meth-ods and instrumentation. The book is unique in itsbroad subject coverage, incorporating fundamentaltechniques as well as applications of modern molec-ular and proteomic tools that are the basis for state-of-the-art research.

"The proposed book is an excellent one for use ofstudents, research scholars and teachers of life sci-ences, biotechnology, biochemistry, biophysics andother related disciplines where such books exclu-sively dedicated for life sciences are not available."

—Prof. Sukh Mahendra Singh, Coordinator, School ofBiotechnology, Banaras Hindu University, India




Biotechnology

BiotechnologyFundamentalsFirdos Alam KhanManipal University, Dubai, UAE

This textbook discusses thefundamentals of biotechnolo-gy as well as the latest devel-opments such as stem cellresearch, cloning, biofuel, transgenic plants, genet-ically modified food or crops, pharmacogenomics,and nano-biotechnology. Incorporating extensivepedagogy into the content, the authors provideexamples, end-of-chapter problems, case studies,and laboratory tutorials.

Features

• Includes information on current research trends • Covers novel medical genetics topics such as

intra-uterine insemination• Discusses the process of biotech product

development, with suitable examples • Examines ethical issues within biotechnology

research and product development (e.g.embryonic stem cells, cloning, gene therapy,and GM crops)


• Learning objectives for each chapter• End-of-chapter problems• Lab assignments• Suggestions for field trips


Selected Contents

Introduction to BiotechnologyGenes and GenomicsProteins and ProteomicsRecombinant DNA TechnologyMicrobial BiotechnologyAgricultural BiotechnologyAnimal BiotechnologyEnvironmental BiotechnologyMedical BiotechnologyNanobiotechnologyProduct Development in BiotechnologyIndustrial BiotechnologyEthics in BiotechnologyCareers in BiotechnologyLaboratory TutorialsGlossary

Catalog no. K11059, September 2011, 608pp.,ISBN: 978-1-4398-2009-4, $93.95 / £49.99Also available as an eBook

BiotechnologyOperationsPrinciples andPractices

Michael J. RoyUniversity of Wisconsin-Madison, USA

Applying the author's experi-ence teaching the subject and working in bothindustry and government, BiotechnologyOperations: Principles and Practices introduceskey biotechnology developments and covers criticalelements, such as project management, regulatoryaffairs, quality assurance, biomanufacturing, qualitycontrol, nonclinical safety testing, and clinical eval-uation.

Features

• Provides an introduction to each key biotech-nology development subject, all compiled inone volume

• Incorporates an integrated approach, tyingtogether the seven key functional areas

• Emphasizes the need to both plan and integrate an operations program, offering theinformation required to successfully lead suchefforts

• Uses relatively simple language, clarifies jargon,and uses diagrams to describe processes, making concepts easy to understand


• Practical problems and questions• A glossary


Selected Contents

Introduction to Biotechnology Operations:Planning for SuccessProject ManagementRegulatory AffairsRegulatory ComplianceQuality SystemsBiomanufactureQuality ControlNonclinical StudiesClinical TrialsGlossaryAdditional ReadingPractical Problems and Questions

Catalog no. K11486, March 2011, 416 pp.ISBN: 978-1-4398-3027-7, $104.95 / £66.99Also available as an eBook




21

Biotechnology


HealthcareBiotechnologyA Practical Guide

Dimitris DogramatzisDogramatzis Pharmacy, Athens, Greece

"The section on marketing isalso particularly strong andwell thought through. ... pro-vides insight into the biotech-nology business sector."

—British Journal of Biomedical Science

Focusing on the management of healthcare relatedbiotechnology, this is a practical guide assisting pro-fessionals in their day-to-day activities. It containschapters on bioeconomy, biolicensing, biofinance,biopartnering, biodrug research, biomarket plan-ning, biopromotion, product life-cycle manage-ment, and biobusiness models. Written by a well-established professional and registered pharmacist,this reference is appropriate for graduate studentsand industry professionals. A solutions manual, instructor’s manual, and figure slides

are available upon qualifying course adoption.

Catalog no. K12108, December 2010, 689 pp.ISBN: 978-1-4398-4746-6, $109.95 / £69.99Also available as an eBook

Systems BiologyandBioinformaticsA ComputationalApproach

Kayvan Najarian,Christopher N.Eichelberger, Siamak Najarian, and Shahriar Gharibzadeh

Emphasizing computational methods, SystemsBiology and Bioinformatics provides an introduc-tion to systems biology and its impact on biologyand medicine. It reviews basic principles of molecu-lar and cell biology using a system-orientedapproach, with a brief description of the high-throughput biological experiments that producedatabases. The methods presented include tech-niques to discover genes, perform nucleotide andamino acid sequence matching, and estimate staticgene dynamic pathways. It also explains applica-tions for system-oriented models to predict thebehavior of biological systems.


Catalog no. 46500, April 2009, 190 pp.ISBN: 978-1-4200-4650-2, $79.95 / £49.99Also available as an eBook

EnvironmentalMicrobiology forEngineersVolodymyr IvanovNanyang Technological University,Singapore

Designed specifically for engi-neers with little or no biologytraining, this book coversdiversity and function ofmicroorganisms in environmental engineering sys-tems, environmental bioengineering processes,applied microbial genetics and molecular biology,microbiology of water and wastewater treatment,biotreatment and bioremediation, and microbialmonitoring. It also explores biocorrosion of the con-structions, biodeterioration of the materials, bioce-mentation and bioclogging of soil, biopollution ofindoor environment, and biofouling of the facilities.Each chapter includes quizzes and tutorials.


Catalog no. 92340, November 2010, 438 pp.ISBN: 978-1-4200-9234-9, $109.95 / £69.99Also available as an eBook

Colloids andInterfaces in Life Sciences and Bionano-technologySecond Edition

Willem Norde

This classroom-tested reference presents a conciseintroductory treatment of the physicochemicalprinciples that determine interrelated colloidal andinterfacial phenomena and their relevance to vari-ous life sciences. The book focuses on concepts thatform the basis for understanding this behavior. Itdeciphers the spontaneous assembly of amphiphilicmolecules and discusses the intentional fouling ofsurfaces for the immobilization of cells in bioreac-tors. It also devotes special attention to reversibleand soft colloids and examines the colloidal domainin a historical perspective, the size and distributionof particles, electrokinetic phenomena, and more.

Catalog no. K10890, June 2011, 495 pp.ISBN: 978-1-4398-1718-6, $134.95 / £39.99Also available as an eBook







General Textbooks

Forthcoming

NumericalMethods forChemicalEngineers UsingExcel, VBA, andMATLAB®

Victor J. Law

Since most practical engineering problems must besolved numerically, this text provides instruction onusing numerical methods and Excel®/VBA for chem-ical and biomolecular engineering problems. It alsoincludes an introduction to MATLAB®. The book isthe first to apply numerical methods specifically forchemical engineers in the Excel/VBA computingenvironment. All examples and exercises emphasizechemical and biomolecular engineering applica-tions. The book also contains homework problemsin each chapter.


Catalog no. K16702, March 2013, c. 252 pp.ISBN: $59.95 / £38.99Also available as an eBook

A First Course in DifferentialEquations,Modeling, andSimulationCarlos A. Smith andScott W. Campbell

Emphasizing a practical approach for engineers andscientists, this text avoids overly theoretical explana-tions and shows readers how differential equationsare derived by applying basic physical principlesand experimental observations to engineering sys-tems. This resource also covers classical methods forobtaining the analytical solution of differentialequations and Laplace transforms. In addition, theauthors discuss how these equations describemathematical systems and how to use software tosolve sets of equations in which analytical solutionscannot be determined. Numerical values are pro-vided in all examples and problems.



TechnicalWritingA Practical Guide for Engineers and Scientists

Phillip A. Laplante

Written by a renowned engi-neer and widely publishedtechnical author, this guideenables readers to write, edit, and publish materialsof a technical nature, including books, articles,reports, and electronic media. Complementing thetraditional writer’s reference manuals and otherbooks on technical writing, it helps readers under-stand the practical considerations in writing techni-cal content. Drawing on his own work, the authorpresents many first-hand examples of writing, edit-ing, and publishing technical materials. Theseexamples illustrate how a publication originated aswell as various challenges and solutions.

Catalog no. K11106, July 2011, 250 pp.Soft Cover, ISBN: 978-1-4398-2085-8$41.95 / £26.99Also available as an eBook

RandomPhenomenaFundamentals ofProbability andStatistics forEngineers

Babatunde A. Ogunnaike

“... distinguished from the crowded field by thewell-explained theory of statistics and how it provides interesting applications.”—Walid K. Sharabati, The American Statistician, August 2011

“... many unique features ... Instructors who arelooking for an alternative textbook should give aserious consideration to adopting this book.”

—Ali Cinar, Technometrics, August 2011

“I would have loved to be taught from a book likethis and I heartily recommend this book as a class-room textbook for both the clarity of the explana-tions and the amount of material covered.” —Pieter Bastiaan Ober, Journal of Applied Statistics, 2011








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Bioengineering and Biotechnology Courses

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Transcript of Bioengineering and Biotechnology Courses