BIOCON Company Profile

8/8/2019 BIOCON Company Profile

http://slidepdf.com/reader/full/biocon-company-profile 1/6

BIOCON Company Profile Biocon is India's leading integrated biotechnology enterprise focused on the development

of biopharmaceuticals. Since its inception Biocon has evolved from an

enzymemanufacturing company to a fully integrated biopharmaceutical enterprise,

focused on healthcare. Biocon has successfully forayed into drug discovery and

development. It has developed innovative and effective biomolecules in diabetology,

oncology, cardiology and other therapeutic segments. Biocon delivers products and

solutions to partners and customers in over 50 countries.

Biocon was founded on November 29, 1978 as a joint venture between Biocon

Biochemicals Ltd. of Ireland and an Indian entrepreneur, Kiran Mazumdar Shaw. In

1979, Biocon became the first Indian company to manufacture and export enzymes to

USA and Europe. Unilever plc. acquired Biocon Biochemicals Ltd. in Ireland in 1979 and

merged it with its subsidiary, Quest International. In 1989, Biocon became the first

Indian biotech company to receive US funding for proprietary technologies. In 1993,

Biocon's R&D and manufacturing facilities received ISO 9001 certifi cation from RWTUV,Germany. In 1994, Biocon established a subsidiary Syngene International Pvt. Ltd to

address the growing need for outsourced R&D in the pharmaceutical sector. In 1996,

Biocon entered the biopharmaceuticals and statins segment. In 1998, Unilever sold its

shareholding in Biocon to the Indian promoters and Biocon became an independent

entity. In 2000 Biocon commissioned its first fully automated submerged fermentation

plant to produce speciality pharmaceuticals. In the same year Clinigene, India's first

clinical research organisation and a subsidiary of Biocon, was set up to pursue

clinical research and development. In 2001, Biocon became the first Indian company to

be approved by US FDA for the manufacture of lovastatin, a cholesterol-lowering

molecule. In 2003 Biocon became the first company worldwide to develop human insulin

on a Pichia expression system. In 2004, Biocon entered the stock market with

its IPO and became only the second Indian company to cross the $ 1 billion mark on theday of listing. In 2006, Biocon launched India's first cancer drug BIOMAb EGFR.

Products & Services Offered by Biocon:

1. Biopharmaceuticals: Today, Biocon is a leading biopharmaceutical company with

strong capabilities in statins, immunosuppressants, recombinant insulin and a wide

product range across key therapeutic segments including diabetology, cardiology and

oncology. Following biopharmaceutical products are offered by Bi ocon:

o Small molecules: Biocon produces anti-diabetic agents, anti-hypertensiveagents, anti-inflammatory agents, anti-oxidants, cardiovascular agents, digestive-

aid enzymes, hemostatic agents, hepatoprotective agents, immunosuppressants,and neutraceuticals.

o Biologicals: In the field of Biogenerics, Biocon is currently working on products

that include: Insulin, Streptokinase, and Monoclonal Antibodies. o Dosage Forms: Biocon provides products in the therapeutic segments of

cardiology and diabetes.

2. Enzymes: Biocon is India's largest producer and exporter of enzymes. It

manufactures and markets a broad range of industrial enzymes, food additives and



process aids. Biocon is the first enzyme company globally to receive the ISO 9001

accreditation. Enzymes manufactured by Biocon are: Amylases, Amyloglucosidases,

Cellulases, Catalase, Lipases, Glucanases, Hemicellulases, Phytases, Proteases, and

Pectinases.

3. Custom Research: Biocon subsidiary Syngene conduct high value R&D in early stage

drug discovery and development for a diverse global clientele.

4. Clinical Research: Biocon subsidiary Clinigene offers global biotechnology and

pharmaceutical majors strong clinical trial services, regulatory and laboratory capabilities

for clinical drug development. Its value added services include value-added services

include patient registries and clinical databases in diabetes, lipidemia, oncology,

cardiovascular diseases.

Major Achievements of Biocon:

o First Indian company to manufacture and export enzymes to USA and Europe. o First Indian biotech company to receive US funding for proprietary technologi es.

o First Indian company to be approved by US FDA for the manufacture of lovastatin, a cholesterol-lowering molecule.

o First company worldwide to develop human insulin on a Pichia expression system.

o India's largest producer and exporter of enzymes.

o Second Indian company to cross the $ 1 billion mark on the day of listing.

o Launched India's first cancer drug BIOMAb EGFR

Biocon Placement Paper(Chemistry)

(1) A reaction was found to be second order with respect to the concentration

of carbon monoxide. If the concentration of carbon monoxide is doubled, with everythingelse kept the same, the rate of reaction will

(a) remain unchanged(b) triple

(c) increase by a factor of 4

(d) double

Answer (c) increase by a factor of 4

(2) HBr reacts with CH2 = CH ± OCH3 under anhydrous conditions at room temperatureto give

(a) CH3CHO and CH3Br(b) BrCH2CHO and CH3OH(c) BrCH2 ± CH2 ± OCH3

(d) H3C ± CHBr ± OCH3

Answer (d) H3C ± CHBr ± OCH3

(3) The IUPAC name for the complex [Co(NO2)(NH3)5]Cl2 is



(a) nitrito-N-pentaamminecobalt (III) chloride

(b) nitrito-N-pentaamminecobalt (II) chloride(c) pentaammine nitrito-N-cobalt (II) chloride

(d) pentaammine nitrito-N-cobalt (III) chloride

Answer (d) pentaammine nitrito-N-cobalt (III) chloride

(4) The term anomers of glucose refers to

(a) isomers of glucose that differ in configurations at carbons one and four (C-1 and C-4)(b) a mixture of (D)-glucose and (L)-glucose

(c) enantiomers of glucose

(d) isomers of glucose that differ in configuration at carbon one (C-1)

Answer (d) isomers of glucose that differ in configuration at carbon one (C-1)

(5) Phenyl magnesium bromide reacts with methanol to give

(a) a mixture of anisole and Mg(OH)Br

(b) a mixture of benzene and Mg(OMe)Br(c) a mixture of toluene and Mg(OH)Br

(d) a mixture of phenol and Mg(Me)Br

Answer (b) a mixture of benzene and Mg(OMe)Br

(6) The pyrimidine bases present in DNA are

(a) cytosine and adenine

(b) cytosine and guanine

(c) cytosine and thymine(d) cytosine and uracil

Answer (c) cytosine and thymine

(7) Among the following mixtures, dipole-dipole as the major interaction, is present in

(a) benzene and ethanol

(b) acetonitrile and acetone

(c) KCl and water(d) benzene and carbon tetrachloride

Answer (b) acetonitrile and acetone

(8) Fluorobenzene (C6H5F) can be synthesized in the laboratory

(a) by heating phenol with HF and KF(b) from aniline by diazotisation followed by heating the diazonium salt with HBF4(c) by direct fluorination of benzene with F2 gas

(d) by reacting bromobenzene with NaF solution

Answer (b) from aniline by diazotisation followed by heating the diazonium salt with

HBF4



(9) A metal, M forms chlorides in its +2 and +4 oxidation states. Which of the following

statements about these chlorides is correct?

(a) MCl2 is more volatile than MCl4(b) MCl2 is more soluble in anhydrous ethanol than MCl4

(c) MCl2 is more ionic than MCl4(d) MCl2 is more easily hydrolysed than MCl4

Answer (c) MCl2 is more ionic than MCl4

(10) Which of the following statements is true?

(a) H3PO3 is a stronger acid than H2SO3

(b) In aqueous medium HF is a stronger acid than HCl

(c) HClO4 is a weaker acid than HClO3(d) HNO3 is a stronger acid than HNO2

Answer (d) HNO3 is a stronger acid than HNO2

Biocon Chemistry Paper - August

(1) Toluene is nitrated and the resulting product is reduced with tin and hydrochloric

acid. The product so obtained is diazotised and then heated with cuprous bromide. The

reaction mixture so formed contains

(a) mixture of oí and píbromotoluenes

(b) mixture of oí and pídibromobenzenes(c) mixture of oí and píbromoanilines

(d) mixture of oí and míbromotoluenes

Answer (a) mixture of oí and píbromotoluenes

(2) Phenol, when it first reacts with concentrated sulphuric acid and then withconcentrated nitric acid, gives

(a) 2,4,6-trinitrobenzene

(b) o-nitrophenol

(c) p-nitrophenol(d) nitrobenzene

Answer (b) o-nitrophenol

(3) Larger number of oxidation states are exhibited by the actinoids than those by the

lanthanoids, the main reason being

(a) 4f orbitals more diffused than the 5f orbitals

(b) lesser energy difference between 5f and 6d than between 4f and 5d orbitals(c) more energy difference between 5f and 6d than between 4f and 5d orbitals

(d) more reactive nature of the actinoids than the lanthanoids

Answer (b) lesser energy difference between 5f and 6d than between 4f and 5d orbitals



(4) Which of the following factors is of no significance for roasting sulphide ores to the

oxides and not subjecting the sulphide ores to carbon reduction directly?

(a) Metal sulphides are thermodynamically more stable than CS2(b) CO2 is thermodynamically more stable than CS2

(c) Metal sulphides are less stable than the corresponding oxides(d) CO2 is more volatile than CS2

Answer (a) Metal sulphides are thermodynamically more stable than CS2

(5) -D-(+)-glucose and -D-(+)-glucose are

(a) conformers

(b) epimers

(c) anomers(d) enantiomers

Answer (c) anomers

(6) Which one of the following is the correct statement?

(a) Boric acid is a protonic acid

(b) Beryllium exhibits coordination number of six

(c) Chlorides of both beryllium and aluminium have bridged chloride structures in solidphase

(d) B2H6.2NH3 is known as µinorganic benzene¶

Answer (c) Chlorides of both beryllium and aluminium have bridged chloride structures insolid phase

(7) Among the following substituted silanes the one which will give rise to cross linked

silicone polymer on hydrolysis is

(a) R4Si

(b) RSiCl3(c) R2SiCl2

(d) R3SiCl

Answer (b) RSiCl3

(8) In a compound atoms of element Y from ccp lattice and those of element X occupy2/3rd of tetrahedral voids. The formula of the compound will be

(a) X4Y3

(b) X2Y3

(c) X2Y(d) X3Y4

Answer (a) X4Y3

(9) Amount of oxalic acid present in a solution can be determined by its titration withKMnO4 solution in the presence of H2SO4. The titration gives unsatisfactory result when

carried out in the presence of HCl, because HCl



(a) gets oxidised by oxalic acid to chlorine

(b) furnishes H+ ions in addition to those from oxalic acid(c) reduces permanganate to Mn2+

(d) oxidises oxalic acid to carbon dioxide and water

Answer (c) reduces permanganate to Mn2+

(10) Which one of the following pairs of species have the same bond order?

(a) CNí and NO+(b) CNí and CN+

(c) Oí and CNí

(d) NO+ and CN+

Answer (a) CNí and NO+

BIOCON Company Profile

Documents

Transcript of BIOCON Company Profile