Biocircuits Lindemann 1990
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BIOCIRCUITS: NEwTEo+{oLocBs IN Wsor-nnc }fuerrn TerryPatteq Tools For Eploration 42atc Redwood Highway San Rafael CA 94903 ncyr. sore pNEiri thd sne bni! dchitg Ning {lE 31ho@ddol6, udydbicnoib mbe mde at Loncin r rfl nom{ilh pd 6d4 onlytDou! i2o. rtryreinvcntdft xtuy]€maso mdhu&.4 of p€pLhuE r6dtrc46rDen@uingrds dee6- €.r, udyer uril lcnrly, biencui$ hrw rcmh d u- publiciu4 doated tn oraclitlY. ft. tandoc sMoudhg bioci.rddt 6ntro&tr1 ny riL lstic ud I ton the €ry b€dmilg or ou M.h tor the b6l Btocxeta..ir@hg NN TMkIU ,,la€rt ,/4. $len lalie b.go r*3!cDl!gtq sbe m u dlbBi,s,i€lry s$n n er or !b. odg!'r "E@4 sM," r lormr bur depriEly stnple aptaats @!- sndngolM @!p€r KeE, ech linlred ry*ird b M opp.rhedleTlesrgtrprlelddidwn .tilgon topotlnede6, odes.Iab€na.blhebeof rhe spile mdlxeorherbcnatlherop of rnesp !h! (s fd inEhdo4 page 14). sl.h.dued$cgesEgnbrlyforabodsilFm' digintly to r.ndc sts or $e erd ofd. mrk day. And 6nen b llnq dnu!6 h Ec@'s "Eberio! ctrqfi" latie ietsh€tad afi6h r*n olturg/iorh.r 4d!3's adiviid B*nhany, whnc vng o! rhc bidn- oit lalie begtuto hFeblistul qpederc in *hich shc *urd r@rmed ourofh6ordiMry ideo!fidliorwidrhe body, onrinuoNpirha neldof plduble encrAtmdio! tuu du!'r ne! jn al didioE. stdrd4 osto6 l! {Dic! ft ss dc cimil s ability to .ftlgrh.rh.r ovrrix h.il!b, tn*crpcricrG we peF ,Ei@ bi*imib *ge m tuoditury bl al boie pdpL shourd ho* abour, Togcrhcr*c aSed lhar snerhilg3hoddb.publishe4ddwended!pvrlting ! 2,40 pag.b@Ldsiblg,stole rd *,Irich rheE€lrh s.fu % onry.nc 6Pd gidrheiMlo!oflhesffiB,rlinle'lotmEnglin' Dd ebtl oller lead b3dte hen hd brd h. tippoed upon biocmirl Me! * ob- i.ired a opy or Emt opu, cdF:dvulatrr!, re rcl@ljheLlddeoledLLjscldicEer,ovdsronyyd Pdio4 ro bft'rdaFtion crtuil" &oE Gbirjbtrg bjui6 slftre{ duirg rhc 6^! worrd we, in *nich he sftd a a pilor, sNivhg onen6lr cidup bynedidl ddod d'100% disble4" F.De rsi.d b rhe libL for guidde daoliio!ri4ltesictstorldbcncdcdnythc'lalingor orbe{b." \lly the Pldal? Wly"!o bdd"? Pcrhqs ou bodi6 wre bi!.I.r tsredt dd perb4slneF*reorto&hu(snard 3.ecsrryd- adL E!@setdioftnhilElldndlrsobcilt ed ! Hy ro lry bu,rs o! ni! (rn mhl ncmu stsrer 1\ltr oppsbmdl4 rooMd thert hcaling innude ot tis bdd! dnedy 6 M sPp€r sde6 sbjcn !€t@ plied benulh rxc bp ud bodon ofhis sphe wld herdyin rxa aPpmtu Ee@ feli a 3mrbing ud poooud Ehnon rle pbe. He s.{ dis dnie dailyh d arlcdp! ro hd biDs€it wfthin a lE,hemIuIyl@vere4 Hcstcnt plorbs nn tur'linay 'lilovorr. EeDe s{bisrigeDenl (hnlion cntuif'6 adi6 dnoery lor mdic.r $ience, a demp€udc @l *ft armGrlinidds appliorios. Hcot6eda priErete€ling ph.d@in rch he !5€dth. r.b&rio! dmir b bar d widermge ol d€di€l srdirios, dd he tePaned sly osindt su@ *id problem rudns fron insonnit b 3dfils ol os.la ,id joht b dep.std psr.b- logislpnbles,lhich Edd @tdd addrs byabg rhe .xdi. ro undx bui.d EeEoris dd motios d@i atd*ilh to'8o!e! ciildhmd ta'M. b ni56ti6t rhmreriral iNsligalioa, Ft1m djdr *ris of eiperituna in *hi.h he nrppal rhre d6 or polqirysidin de tmb bod]rtsd b rm( len ro iig4 In@ctilgy cnoug\ his tudins: pumc ehich viw tlae a6 dr poldit s b.ttc lir- tdg ba]lle \{xi! rhc bMe body.He loud 1b,. wher hc 6d€ded tne righrbnd rolhe bsortu spine, mdlbe left to lnerop ofrhe spjle, arlzedon cinilm romea TlepeBorlyinsin$ecnd muldreL:'l4Pl, tcqneorry being eaM ioroadeply refrshing slep. Bur {hd rxe haldld *crc dchsgcA onndi.g se rop ot rhe spine r rnenghl hrd u'r rhr boron oI rhc spirdo lnelefi, rhcpesorlyilg iDcnoi voddbmle imbble, resdduodrdtublqaequenty4en goingsoEr$ ro Aner he op.rcd hn tesling pndie, F,tln loud sonc P@Plc *ho wrc s *c.t ud cn erg/ inro rls relas iion cimir E lM risgd up sne dalirs ad h?dr6 dd raydM !d ro hrs !atje!6, didry omde{ to tten .trerg/ nos, Hc foud rb{ the deply s@!bj!8 efie.! of .he bisnojr uere [email protected]€lly i!d6e4 0. lsr nos of .he tihe. E M €!€d rhis pBcrie ol omdbg M or nore pmpte rogerhs i! a silgl. legc Pas614 itebJn.J,jtrltg@1990 neJdtltd d M RM')
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Transcript of Biocircuits Lindemann 1990
BIOCIRCUITS: NEw TEo+{oLocBs IN Wsor-nnc }fuerrnTerry Patteq Tools For Eploration
42atc Redwood HighwaySan Rafael CA 94903
ncyr. sore pNEiri thd sne bni! dchitgNing {lE 31ho@ddol6, udydbicnoib mbemde at Loncin r rfl nom{ilh pd 6d4 only tDou!i2o. rtryreinvcntdft xtuy]€maso mdhu&.4of p€pLhuE r6dtrc46rDen @uingrds dee6-€.r, udyer uril lcnrly, biencui$ hrw rcmh d u-publiciu4 doated tn oraclitlY.
ft. tandoc sMoudhg bioci.rddt 6ntro&tr1ny riL lstic ud I ton the €ry b€dmilg or ouM.h tor the b6l Btocxeta..ir@hg NN TMkIU,,la€rt ,/4. $len lalie b.go r*3!cDl!gtq sbe mu dlbBi,s,i€lry s$n n er or !b. odg!'r "E@4sM," r lormr bur depriEly stnple aptaats @!-sndng olM @!p€r KeE, ech linlred ry*ird b Mopp.rhedleTlesrgtrprlelddidwn .tilgontopotlnede6, odes.Iab€na.blhebeof rhe spilemdlxeorherbcnatlherop of rnesp!h! (s fd inEhdo4 page 14).
sl.h.dued$cgesEgnbrlyforabodsilFm'digintly to r.ndc sts or $e erd ofd. mrk day.
And 6nen b llnq dnu!6 h Ec@'s "Eberio!ctrqfi" latie ietsh€tad afi6h r*n olturg/iorh.r4d!3's adiviid B*nhany, whnc vng o! rhc bidn-oit lalie begtu to hFeblistul qpederc in *hich shc*urd r@rmed our ofh6ordiMry ideo!fidliorwidrhebody, onrinuoNpirha neld of plduble encrAtmdio!tuu du!'r ne! jn al didioE.stdrd4 osto6 l! {Dic! ft ss dc cimil s ability to.ftlgrh.rh.r ovrrix h.il!b, tn*crpcricrG we peF,Ei@ bi*imib *ge m tuoditury bl al boiepdpL shourd ho* abour, Togcrhcr *c aSed lharsnerhilg3hoddb.publishe4ddwended!pvrlting !2,40 pag.b@L dsiblg,stole rd*,Irich rhe E€lrh s.fu % onry.nc 6Pd
gidrheiMlo!oflhesffiB,rlinle'lotmEnglin'
Dd ebtl oller lead b3d te henhd brd h. tippoed upon biocmirl Me! * ob-i.ired a opy or Emt opu, cdF:dvulatrr!, re
rcl@ljheLlddeoledLLjscldicEer,ovdsronyydPdio4 ro bft'rdaFtion crtuil"
&oE Gbirjbtrg bjui6 slftre{ duirg rhc 6^! worrdwe, in *nich he sftd a a pilor, sNivhg one n6lrcidup by nedidl ddod d'100% disble4" F.Dersi.d b rhe libL for guiddedaoliio!ri4ltesictstorldbcncdcdnythc'lalingor
orbe{b." \lly the Pldal? Wly"!obdd"? Pcrhqs ou bodi6 wre bi!.I.r tsredt ddperb4slneF*reorto&hu(snard 3.ecsrryd-adL E!@setdioftnhilElldndlrsobcilt ed! Hy ro lry bu,rs o! ni! (rn mhl ncmu stsrer1\ltr oppsbmdl4 rooMd therthcaling innude ot tis bdd! dnedy 6 M sPp€rsde6 sbjcn !€t@ plied benulh rxc bp ud bodonofhis sphe wld he rdy in rxa aPpmtu Ee@ feli a3mrbing ud poooud Ehnon rle pbe. He s.{dis dnie daily h d arlcdp! ro hd biDs€it wfthin alE,hemIuIyl@vere4 Hcstcntplorbs nn tur'linay 'lilovorr.
EeDe s{bisrigeDenl (hnlion cntuif'6 a di6dnoery lor mdic.r $ience, a demp€udc @l *ftarmGrlinidds appliorios. Hcot6eda priErete€lingph.d@in rch he !5€d th. r.b&rio! dmir b bar dwide rmge ol d€di€l srdirios, dd he tePaned slyosindt su@ *id problem rudns fron insonnitb 3dfils ol os.la ,id joht b dep.std psr.b-logislpnbles,lhich Edd @tdd addrs by abg rhe.xdi. ro undx bui.d EeEoris dd motios d@iatd*ilh to'8o!e! ciildhmd ta'M.
b ni5 6ti6t rhmreriral iNsligalioa, Ft1m djd r*ris of eiperituna in *hi.h he nrppal rhre d6 orpolqirysidin de tmb bod]r tsd b rm( len ro iig4
In@ctilgy cnoug\ his tudins:
pumc ehich viw tlae a6 dr poldit s b.ttc lir-tdg ba]lle \{xi! rhc bMe body. He loud 1b,.wher hc 6d€ded tne righr bnd rolhe bsortu spine,mdlbe left to lne rop ofrhe spjle, a rlzedon cinilmromea TlepeBorlyinsin$ecnd muldreL:'l4Pl,tcqneorry being eaM ioro a deply refrshing slep. Bur{hd rxe haldld *crc dchsgcA onndi.g se rop otrhe spine r rne nghl hrd u'r rhr boron oI rhc spirdolne lefi, rhcpesorlyilg iDcnoi voddbmle imbble,resdduodrdtublqaequenty4en goingsoEr$ ro
Aner he op.rcd hn tesling pndie, F,tln loudsonc P@Plc *ho wrc s *c.t ud cn
erg/ inro rls relasiion cimir E lM risgd up sne dalirs ad h?dr6dd ray dM !d ro hrs !atje!6, didry omde{ totten .trerg/ nos, Hc foud rb{ the deply s@!bj!8efie.! of .he bisnojr uere [email protected]€lly i!d6e4 0.lsr nos of .he tihe. E M €!€d rhis pBcrie olomdbg M or nore pmpte rogerhs i! a silgl. legc
Pas614 itebJn.J,jtrltg@1990 neJdtltd d M RM')
*ldng diaglu "mp€mrirc hcdllg." By sh{ilg rct.q^ utu{ I@ri4 er.rA/, the M oery nctds @"@pc6dng" b*n a mre poc4rhnn arhginnrcDecoop.Eri€ cinfuy b.@ $e sM tor nucr oi EclMt rst tdlsulrs odgid Mrk oE rtc .d. forry
Plrh mpaiieciiois, EcM mded trn llc E-Irdto, ciloir @rt dr gror der ori.ro@ddof bor0p\rialddbentl uh!e, Ttisob*mtiotrtoucdr!.
|hp€utdebriq!6, awn6 rqhol.scd6 oldpsi-DeoB h alNirs iet.pnblc omuierior *itn rc
SomorFr@3 E6t ilrdgulng rkrclru btrq,!€riDctu r{rh rLugs t! rue cinii H. Lld mlied rharpoplc i! @pdtiw clrdia tued ro ,ori€, or €6e 04 st dfc ph$jel ffiios or axpei{e tmrL o|!d pdpre rytus ir ctruL u4rrn .M. Iry dou t! I cnclil *Lilc drnn& tle orheaIrt4 ia rhe sme cinth murd fe€l srgbiy doljr then-3.h8, Om d.r{hile E@! hy hasrcsriwcndirMil . wM sufert4 r 104! f€u ler rdr€*Mdstp.db 1140. Tlerc n remitre4 Tnis s s hr 6 hc6!ldioilldeit lle o.rt€rnE of [email protected] r!. M dt en&i oacksir6*iicrtedrr$tEd M 6"lrtn ebb6. wiain M nhu6, hercnp@tu h.ddbppelb 1000.
J.B, Rhim ofDuL unieefiiq lug36red b E l@oine@M5oEb*i&Dic..rMrbv,*hoERnilchcldhltgleren D.. Mrbyru 6F.i yilrcMr€ilillle.t4of dngslnihe.irdiL A*risotdoubleh[nd6s,@!du.r.{ by Ec@ ud Mlby lie re 6&d€ of aphmologsr pEdd.! sdo.c @!trm.tior ot *!!rE.,Mhdoukrclr Tr.qpsiEen,!.t a D@.! rilt tbe idetrdry ofihe drugs pj,ad ln ne{@r € unroom oorodiy ro rte qDertu d lubic6but al!. rh. @! @ldudhg the t6$. T14 o&frdtyt@ .d o.h drugk ini@!6, ilctudtnS ar pbl iologi-er bd p6r.ior0siet $bjecdc dd objnjv. 6p.6,krq. |j. Dlmoob*nt ondqcd thi! d,b rnn rh.i(iedin6 or the dns! lnlr bad b€a used (1b. tddritislad betr kepr s6q Irod rlc orls D.!). rre $bj4sd aturely .ra{ri.tr*d |!. 'ppoprirk i.nDroe of@.! dsg plle{t i! rbc ctrati.
I!tt!.!- lslie ud I rld a fer dp€rddb ou-..16. Wo rok r s@d{d oppe FlEu rcbqLjo!crrcli dd Nr or. ot rxe *iG. wc stioD€d back rhc in-ruiriio! ed 'ubrersed 4cn .nd ido tsohdon or rhcE@Lunlej}yb€trigD burpturfr !ot,vlmioc ft .sudd.tr3useoIdw Hr M so stolg ed iN.dlieEPsr 0e qPdde turat lins b€foe w m suerDlrr.harolbeDuonrloEt krlwrielrwdo$qurudh.ilingrgd6, ou.ubj4ive dp€de@M u,dbiguou: tbe cinii ereftry did @mulleG u1ft-
doidiniueDq. web.gd ro Imr rorornd cerd.nwno wuld ombone - or b€tui
Duing EeDut M.ritu, hn dng ap.iinda a!trld.rl !h. rdd6t of Di Eric Pordr, a ladilg noDeparh i! E!3lmd dullg rhe toni6 dd ffd4 PftI epared E€Eet dtug dp.dn@6 sitrg hl)mp{6icrdedten hd o.dnded rhlr rh. ftlrnrioD cirul. on
omdlidlryudd@ryrrtlhoursnu! li*or@&nitutids oatyh-36red honmparhic ra.dt6. Pmlrt€gd toe!4lln\.iE nqlhtryinhbpriEEpndtce,borarMlror rd@tid dd 6 a ocd for rdhilislqils r.D.dnro hE pa[ma. He dra.lop.d a ehtu. t6. iMiDgEDdi6 ir@ rlc dmir }ticb he Lrmturir h.rlc* a rnc iarblotu'1iu.' Al.lournrd-.n n b6rr.nM for tu bmt , ft. Iro. Itritu, r.
F,@tdrcuiulalidgBya4rlddin rrrn{boor,PoreIr tumcrd. 6liB rhe Aurono@rrl,6 *iir rcpaeofs M ldne H. r€potu that h. obbilcd osl}hlty good r6uls id lln @ei
By $n ti@ w wc d&tlopiog snc tfrgrigarod&to[Por€I3 sugg6-
dol we b9 h rhc retiBrio. cnod..d b ist's olouMUbe'MtI$ebrc|i.d*1lgsubnas.dId.dlg'
l[pKm'!ridevllllm c Att6 rer mintrG in dc crtuil I f.trscr.rgrz.d Ididnl vd b lr4p ryilg doh ft 6 rtnBl!kdnnln€a 6upleof otsorofrdq *p!rhr rhn.o318!sodsroud.4nu6rhoustt*E adu.rtmd.harthie. em a ay ercra, ws snE!r.l.{ (r eNda!rb,t I atulrrjr do d rel ane. drinrhs ofiE), onff mrslbkjudr '@joa, .y itrcinil*i&nyuircupda*"rmilg i!.n mning$rt o!@ rbM. ElcntiDc,$e $rc lbrdr disDp.ltrd inrhe shon lif,c rlD.
ou und.Ehdirgolllis !*hnoiory dm@d nucttutrherahen w c!tur.red P.er I hd4qni. e Aesi-@ i.wh.r bod i! D51. Lind@trt bto.lrd Gtub,lill E€@ s,d*ropdouto
rnnoh I! rxcpr@ of bn ft4llry suGtulslcr b hal hiNlfvii biocirdiG ljnde@ bem. r $phndane{ !x6dr sbour rhc p.inciplg ud4rying bianotuy, H..r.d*loFd .ho fi6r mjo! ad@6 in bimiroiry side
Lildemis€n€da dctus.oroutsid.tdlasr iorlurc.r orlolc
stuuhroE. bd a qide tuge of vtbndoo,t belbgllr'furjg ilctudingEdio!16. tn d6diar., Mlt Mrrin, ide ncddd d6mi€d SibEtio!8rdriDg," AsLlndeDmd*tbe iqavibn.ioDrlin,nrre n 4g"ned' dnecdy ilro rx. turs| nrdoli6 orrn body. \trreo $c g"il,1:16" lbcft t diBhrstiir
rlb,hrnd daqddan a6*adt Maytun6)ut*ALwst1s$, pag.13
in '!e bodys vibEuoDtl dlE oi6 ud ne P€n'm orheird E Rubliska AL Ldt rlsret€xv. sv uon_dordsoddily@gflok rtitsbtfi inlhebodysenerg,:
.lixiE,;di;o6, or orld rppbtchE Tt€ vibdtiold
saft is o ltdple buL prcftiud mne!. although gEftilg_rhe
r{bEdo; bn\ e{sy,ntjls ephltd€tiotr ro dccFo]( lbd lnilctr4 @ PLre b cn.1nl
No.eihel6, a mix bub€t of uni(s€Iv km3!sun6ds Diu podn€ €rt posidw bmEs in cnditurd Drior MtsB of rhc individut$ elsg p'tutubkneDl!e, I!dud.{ !d. dc emitr'{@is Creh_I'rIv ii@ir c), od, oM {.dc, tood slPptelena othc;r shrch niw r D6jri€ hiEG on d tndivid!'lvhm i@Ed (th* @ dnsr 6od *hst sa jnie 'od@ri ed @ror innrdc soE Peoplc "odd
tlsoi"a"oi opu. e.muct, *t* v.' pt"e tr* *tlrnd rDio a bio.rur. ou b{'drt ciqsiE d dite.iv.trdedbrrl.tvibEtotrdpinm hn|opoturdorrooh@svs$sne in rhccdir tblrrur dbc llbdsv
e'"o *tlou *true puea ion rlc o'cult ti_aiKrib 4 p&dtul rel! ft.v provid. a dtd dpcn_e@of sub{. oets''p.*tulutudo@tut tor iM ctprMdor' bpi6* -d.rlot-.d 'L,i' d.rvdised pstcr) bw6,6c trc. \Lhetr srbshd e b*nd ub uebtoirait, txcydbt. s to infsc lbeirrib6no!'l quaii-dE dn6{y tlto od bo<ti6 .!e€tneld!. U*!3lo!e o!f,ifi sut{66, bteiloia psdu@ bgibl.6ul6
UDtite s oa.y fteEpt6 *nicb (oder ne bdjvidudd.Dol,clluDl.@f6sio!,]neaktuiE-.*uiop*da wlrtdeE ttuc4t.€r'l.enerd dindio! dn dv, votr idme i tuav d*' rd rc- M t6e* fod J"- bodvs m d'u,r
l'iB BIOCIRCTnIAND ITS 1JSBlleildit @ h 6sh.1ed fion 6pp.r or sitL
Tbtr d6ls! E Ery lopre u6t opP€' bi4jrdB eome.tug tr'mB
rlrhsed. ftc bmdl6 ue neld td acn h'n4 ud tbes@smDbccduderthe@prndbonooofrt sPiacTxls ro@ ihc E€nm GdeBl R.hslion cndit
Tbe M oihd r@@dded r,lcnsl omgMdord. rheEe@ oDdbd Rebsnor cxoia ud rle'-iddedu coinny sldnett€l cirdr:
lrsro ue ahi@irNit I-t domdropoituoPp._rtuironeorih. UlBtardo'ngunos ror20loniauG (ls, 'f 6iDg d 5u!5M), ud rebr 6 dcplv ddonDl€rely 6 ]ou tu Tbe bosr trlivesal .M ot rbebi(ncuir rs t6 rblxwto deplv rluvou dd Rliee 5lsll ism. uundto fsl i o ! d*p dep
. B€arre Bod. Mdy p€ople Irc b @ rh.D in be'
"hd th.Y *Ur to gd 6 seP
. Alter IVo*- r5-lo miiurd I! |ne bldrur d.imrksurlyEjwtrb udddgj6 su ft'!rleii @
: c$ Napph& Biociroits m ptotde d.€p reeehnmr ir r@rd t'm., We hrw neld lmv teporo orbur6 l4lc wbo @ 6ppd bi*ndb bt @tup
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if.i"m'i tl,l.D- rtcy ar *t*p "r "or
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.:ublle Bodv sditivirv. The blena {illhelp fd_flirirriE dd sesirize sc6 b rhcx .rleric or subde.!ersi6. l@bdnea@lfor*EiEim.!qplondolTln is grcbly sefur mrpople wbo n€ditste ordosubde b.dyiorlc includils ffi'8e ud bellrgsorlqbr n x eriolable sd helPtu roi wertine,
il6ni@dior* olberpidiG,a)Ded rolA dd tda@ ine cn.ti@ of doe
iac** tq q *irt 'arou ..!rum p'&rrc,vislrrizaiioc. dfErlion, eietu lpe ofdep Psvcno'lociol elf-diffirytui4 sEe b6in d.bin6, Eiousuttniorr mo oeaar;t auai" q6, ed ourd_rhe_
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