Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of...

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Biochemistry Lecture 5

Transcript of Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of...

Biochemistry

Lecture 5

Proteins

Lipids

Enzymes

Ribozymes

Amino Acids

R Groups

Additional Amino Acids

4-hydroxyproline

5-hydroxylysine

Peptides

oxytocin

vasopressin

Cys

Tyr

Phe Gln

Asn

Cys

SS

H2NO

NH2CGlyArgPro

Cys

Tyr

Ile Gln

Asn

Cys

SS

H2NO

NH2CGlyLeuPro

CH C NH CCH OH

O O

CH 2

OO

HH

NHCCHNHCCHNH

O

HO

NH2

C

Tyr–Gly–Gly–Phe–Met Methionine enkephalin

CH2CHCH3

CH3Morphine

O

N

HO OH

CH3

H

H

Tyr–Gly–Gly–Phe–Leu Leucine enkephalin

Enkephalins

Bovine Insulin

Proteins

Proteins

Purification of Proteins

Structure of Proteins

Sequence Varies: Ask 23andMe

Structure of Proteins

Alpha Helices

Beta Strands