7/25/2019 BIO353 StudyGuide Exam 1 Lect7 v.2 2015Spring

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BIO 353 Cell BiologySpring 2015

Exam 1 Study Guide

Lecture 7 The Nucleus, DNA and RNA

Who is Linus Pauling and why is he important?

Who is Rosalind Franklin and why is she important? Who are James Watson, Francis Crick and Wilkins and why are they important?

What are the three different regions of the chromosome described in lecture?

o nderstand and be able to describe the importance and functions of!

Replication origins

Centromeres

What is special about the "#$ packing in the centromeres and what is

the specific name gi%en to the packed "#$ there?

What can a dysfunction of the centromere lead to?

&elomeres

'inetochoreso nderstand "#$ packing and be able to describe the importance and functions of!

(istones

#ucleosomes

(eterochromatin

)uchromatin

"uring what phase of the cell cycle does the le%el of "#$ packing %ary?

"escribe R#$!

o What is the specific term used to describe the cellular process that synthesi*es R#$?

o nderstand and be able to describe the functions of the different types of R#$ +ee

table -./ in lecture slides01 What is the specific term used to describe the cellular process that synthesi*es

proteins from mR#$? What are RNA genes2genes that produce non.coding R#$ +R#$ that is not

mR#$03 and what are their primary functions?

o "escribe R#$ processing, including!

&he three primary purposes of 45 capping and 65 polyadenylation of pre.

mR#$1 mR#$ splicing . including the role of splicesosomes and introns, and the

different ways that genes can be spliced1

Be ale identi!y the l"cati"ns and#"r "rganelles $ithin the cell $here re%licati"n,transcri%ti"n, the di!!erent &inds "! RNA %r"cessing, and translati"n all "ccur $ithin

the cell'