Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o...

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CORPORATE PRESENTATION June 2017 1

Transcript of Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o...

Page 1: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

CORPORATE PRESENTATION

June 2017

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Page 2: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

DisclaimerCautionary StatementsThis presentation contains “forward‐looking statements” within the meaning of the federal securities laws. Except for historical information contained herein, the statements in this presentation are forward‐looking and made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward‐looking statements made herein relate to, among other things, future sales, earnings, return on equity, cost savings, process improvements, free cash flow, share repurchases, capital expenditures, acquisitions, benefits of investments and partnerships, business strategies and other matters. Such statements can be identified by words such as: “expected,” “expects,” “expect,” “forecast,” “would,” “estimate,” “will,” or similar references to future periods. 

Forward‐looking statements are neither historical facts nor assurances of future performance. Instead, they are based only on our current beliefs, expectations and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy and other future conditions. Because forward‐looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control.  Actual results could differ materially from those stated or implied in the forward‐looking statements. For a list of factors, risks and uncertainties which could make our actual results differ from expected results, please see our latest Annual Report on Form 10‐K. We undertake no obligation to publicly update any forward‐looking statement, whether written or oral, as a result of new information, future developments or otherwise.

This presentation also contains non‐GAAP financial information. Management uses this information in its internal analysis of results and believes this information may be informative to investors in gauging the quality of our financial performance, identifying trends in our results and providing meaningful period‐to‐period comparisons. For definitions of applicable non‐GAAP financial measures and reconciliations of non‐GAAP financial information to GAAP financial information, see the Reconciliations of GAAP to Non‐GAAP Financial Measures included in the Company’s financial reports on Forms 10‐Q and 10‐K and related press releases.

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Page 3: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Bio‐Techne Business OverviewAt a Glance:President and CEO: Chuck KummethHeadquarters: Minneapolis, MNNumber of Employees: 1,700FY2016 Revenues: $499 millionNASDAQ: TECHMarket Cap: $4.2B 

Market Profile:Leader in:‐ Life Science Consumables Market‐ Automated Protein Analysis Solutions‐ Controls & Calibrators for IVD Assays‐ Molecular Anatomic PathologyAddressable Market Size: ~$5‐10 billion

Key Product Lines and Workstreams:Biological ContentAutomated Western BlotSingle and Multiplex ImmunoAssaysRNA‐ISH Molecular Diagnostics 

36%

23%

25%

17%

Revenue by Customer Segmentation

Pharma/Biotech

Academia

OEM

Distributors

59%27%

14%

Revenue by Geography

Americas EMEA APAC

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Page 4: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Our Vision

• Expanding our product portfolio with New & Innovative research tools

• Delivering more complete solutions through a greater diversity of technologies

• Geographic expansion with continued focus on China

• Focusing on products that bring us closer to the “clinic” by leveraging diagnostic and bioprocess applications

• Extract maximal value from the “treasure trove” of reagents developed over the past 40 years

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Page 5: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Our Mission

80%

12%

8%

Headcount by Geography

North America

EMEA

APAC

1,700Employees

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In excess of 200 employees hold PhD degree

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A Great Big Welcome and Hello

North America

Minneapolis

San Marcos

Devens

Cambridge

San Jose

Newark

Emeryville

Littleton

Oakville

Toronto

Ottawa

Wallingford

Europe

Abingdon

Langley

Bristol

Wiesbaden

Lille

Milan

Zug

Asia

Shanghai

Beijing

Hong Kong

Singapore

Tokyo

Total Geographic Sites – 24Total WW Employees ‐ 1700

Global Locations

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Page 7: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Subsidiary Model

Biotechnology

Diagnostics

Protein Platforms

Americas

EMEA

APAC

Collaboration Structure

‐ Commercial teams collaborations‐ Global prioritization‐ Global capital planning‐ M&A

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Divisions (Own Strategy)

Regions(Own Execution)

Page 8: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Current Reportable Segments & Brands

~64% of Sales~80% Gross Margin

Low 50s Op. Margin%

~15% of SalesHigh 60s GM%

High single‐digit OM%

~21% of SalesMid 40s Gross Margin%

~ 30% Op. Margin

Note:  All margin percentages have been adjusted to exclude impact of acquisition costs

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Page 9: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Large Addressable Markets

Customers Servedo Pharmao Biotecho Academiao CROso Hospitalso Foundationso Government

$5B‐$10B Addressable 

Market 4‐10% CAGR

Life Science Research Reagents$1.8B   Tumor 

Biology $0.8B

Stem Cells$0.9B

Research Immunoassay 

$0.7B

Diagnostics $4.2B

ClinicalControls$0.4B

BioProcessMedia $1.6B

Single Cell Biology$0.9B

Western Blot$0.5B

Biologics Manufacturing

$0.6B

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Page 10: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Minneapolis Headquarters Offices and Labs

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Space: 950,000 ft2

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Global Bio‐Techne Locations

Abingdon, UK Office

Langley, UKWarehouse

Newark, CA ACD Office Devens, MA, Offices

Bristol, UK Offices

Shanghai PG labs

Milan, Italy Office

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ProteinSimpleJapan  Office

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Collaboration Programs• Active collaboration with over 50 Key Opinion Leaders to better identify product needs 

(Univ. of Minnesota, Mayo Clinic, Univ. of Pennsylvania, Stanford, etc.)

• Committed to educating life science researchers on BioTechne’s products and their role in enabling life science research activities

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Our Business Today

Develop and manufactures biological reagents used in all aspects of life science research (Research Tools such as: proteins, antibodies, & immunoassays) and molecular probes for the Molecular Pathology market 

Automated solutions that improve the efficiency of process work streams, such as: automated western blot instruments, bioprocess purity analyzers, microfluidic imaging instruments, multiplex‐ELISA instruments, etc.

Provide controls, calibrators and diagnostic assays for the regulated diagnostic market, such as: hematology controls, blood gas and chemistry controls, diagnostic assays reagents

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Page 14: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Proteins

Small MoleculesStem Cell 

Products

StemXVivo®

ELISAs AntibodiesProteome Profiler Arrays

LuminexRNA‐ISH

Biotechnology Division

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Page 15: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Separation

Imaging

Analysis

Microfluidics

Immunoassay

Measurement

Proteins are complex!

Protein Platforms Division

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Page 16: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Diagnostics Division

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Page 17: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

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Key Technologies with Diagnostic Applicability 

• ACD’s RNAscope (RNA in‐situ Hybridization)

• PPD’s Ella Multiplex Instrument 

Ella

Page 18: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

• Acquired in August 2016

• Newark, CA based company with ~150 employees

• Developed technology to improve detection of genes and gene transcripts using probes (in‐situ hybridization) with initial focus on RNA transcript detection (RNAScope)

• Key technology improvements:• Binding specificity to target RNA• Better signal amplification (b‐DNA)• Retention of morphological context

• Could be an aid to pathology practices where IHC reagents are deficient or lacking

• 13,000 current products, first commercialized in 2011, sold to both research and clinical customers

Advanced Cell Diagnostics

18RNAscope VENTANA LEICA

Probe: a synthetic short nucleic acid sequence complementary to the gene sequence of interest

Page 19: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Comparison of RNAscope® to other Dx Platforms for HPV Testing

RNAscope IHC DNA ISHPCR

(Roche Cobas)

Hybrid Capture

(Qiagen HC2)

RT PCR (HologicAptima)

Target HPV E6/E7mRNA P16 HPV DNA HPV DNA HPV DNA HPV E6/E7

mRNA

Evidence of Viral Activity √ ‐ ‐ ‐ ‐ √

Morphologic Context +++ +++ +++ ‐ ‐ ‐

Sensitivity +++ +++ + +++ ++ ++

Specificity +++ + +++ +++ +++ +++

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Page 20: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Fullfillment of an Unmet Need – In Situ RNA Analysis

• IHC and FISH are the leading tools for research & tissue diagnostics• No sensitive and robust technology for in situ RNA detection prior to RNAscope• RNAscope provides complementary information to FISH and IHC

DNA RNA Protein

FISH 1990s

IHC 1970s

RNAscope®

2012

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Page 21: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Ella Features Suitable for Diagnostic Applications

Ella

• Addresses low‐plex multi analyte immunoassay analysis:  (16 samples/4 analytes)

• Parallel immunoassay operation, thus avoiding “cross‐talk” between assays

• Hands off operation (removes operator bias)

• Quick turn around time (1 hr to results)

• Excellent performance (precision and dynamic range‐4 log S/N)

• Embedded standard curve (removes need to run standard curve)

• Closed platform: (controls performance and biological sample handling)

• Small sample volume requirements (~25 L)

• Small Footprint (WxDxH=37x54x26 cm)21

Page 22: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Targets withROIC > WACC

Targets that fill perceived gaps

Sound prioritization strategy

Healthy hopper of targets

Disciplined M&A and Investment Strategy

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Page 23: Bio-Techne Corp Deck FINAL June 2017 · Large Addressable Markets Customers Served o Pharma o Biotech o Academia o CROs o Hospitals o Foundations o Government $5B‐$10B Addressable

Bio‐Techne Summary

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