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Bio 230-Blood Worksheet 1. What are the 2 components of whole blood? 1. 2. 2. What are 3 main components of plasma? 1. 2. 3. 3. What are the three formed elements in the blood? 1. 2. 3. Why are erythrocytes not considered “true” cells? 4. Name 3 functions of blood 1. 2. 3. State whether the following characteristics describe rbc, wbc, or platelets:

5. also known as leukocytes __________

6. has an average life cycle of 120 days __________

7. involved in clotting __________

8. also known as erythrocytes __________

9. biconcave shaped, non nucleated __________

10. involved in fighting infection __________

11. contains hemoglobin to transport Oxygen __________

Match the following types of white blood cells to their function:

12. neutrophils _________ a. produce antibodies

13. eosinophils_________ b. release histamine and heparin

14. basophils__________ c. phagocytes, first to respond to infection

15. monocytes _________ d. fight parasitic infections

16. lymphocytes________ e. the largest wbc, become phagocytes

(macrophages) in tissue

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Leukocyte Table:

Leukocyte Granulocyte or Aganulorcyte

Drawing: Label: nucleus(i) and Granules if present

% in blood

Function

Neutrophil Size relative to RBC=

Lymphocyte Size relative to RBC=

Monocyte

Size relative to RBC=

Eosinophil

Size relative to RBC=

Basophil Size relative to RBC=

REMEMBER: Never Let Monkeys Eat Bananas (most abundant to least abundant WBC)

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Questions: What is the difference between hematopoiesis and erythropoiesis? What is the function of the hormone Erythropoietin (aka EPO)? What organ makes erythropoietin and what triggers its release? ______________________________________________________________________________ Here is an example of how a CBC (complete blood count) will look in a lab report. Notice the WBC count is 6.1 X 103, That is the total WBC count! 103 means this is 6.1 thousand total WBC in the blood. Normal range (right column) is 3.4-10.8 thousand . Now look a the RBC count. 5.97 X 106. . 10 6 tells you this is 5.97 MILLION RBC’s in the blood. So when you look at a blood smear under the microscope you are seeing mostly RBC’s. The differential count is related to the different WBC type. Just under the platelet count you will see the WBCs listed in order (Never let monkeys eat bananas) Neutrophils, lymphocytes, monocytes, eosinophils, basophils. Every lab report will have them listed in this exact order! This report has a slightly elevated RBC count and hematocrit (HCT). Things to think about. Why might his RBC count be high? What if I told you he was a smoker, had some mild lung disease? And his measured PO2 (oxygen measured in his blood) was slightly low (below normal). Could you figure out what might be going on?

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If the patient had a low RBC count, low HCT what could be going on? We use the term “anemia” for conditions that have low RBC counts, but the causes are many! Diet (ex low iron), to blood loss (from bleeding, acute or chronic) or bone marrow problems! A CBC can tell us a lot, for now know the basics, understand what triggers erythropoiesis and where our blood elements are made (ie red bone marrow). If a patient how a high WBC total count (leukocytosis) you could assume they had some type of infection. WBC count usually in 11,000- 18, 000 range. You would then look at the differential count. The patients clinical presentation will help clue you in to what might be going on. If the WBC is low (leukopenia) what could be suppressing the WBC count? Things all nurses will grow to understand. The point of me telling you this is to re-enforce that you are learning anatomy as the bases of all that is to come. Then there is this: WBC counts over 25,000

Look at all those WBCs!!! This is a form of LEUKEMIA. Uncontrolled production of WBCs. A bone marrow biopsy would tell you what is going on. Where do we do bone marrow biopsies? Blood is your river of life!!