BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... ·...

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BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. J Lipid Res, 39(6): 12806. Abdel-Hameed. and El-Sayed Saleh. (2009). Total phenolic contents and free radical scavenging activity of certain Egyptian Ficus species leaf samples. Food Chemistry, 114: 12711277. Abdullahil, B.M., Robiul, I., Sharifun, N.I., Khurshi, A.H.M., Bytul, M., Sadik, G. and Mondal, K. (2007). Sub-acute toxicity study of the compound 4-methoxy-6-carboxy-benzofuran isolated from Derris indica. Res.J.Med. Sci, 2(2): 106-110. Abu-Elheiga, L., Matzuk, M.M., Abo-Hashema, K.A. and Wakil, S. (2001). J. Science, 291: 2613. Adams, L.A. and Angulo, P. (2005). Recent concepts in non-alcoholic fatty liver disease. Diabet Med, 22: 112933. Adiels, M., Taskinen, M.R., Packard, C., Caslake, M.J., Soro-Paavonen, A. and Westerbacka J. (2007). Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia, 49: 75565. Agarwal, S. and Rao, A.V. (2000). Tomato lycopene and its role in human health and chronic diseases. Canadian Medical Association Journal , 163(6): 739−744. Ahmed, M.H., Byrne, C.D (2007). Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD). Drug Discovery Today, 12:740747. Ahmed, M.M. and Zaki, N.I. (2009). Assessment the Ameliorative Effect of Pomegranate and Rutin on Chlorpyrifos-ethyl-Induced Oxidative Stress in Rats. Nature and Science, 7(10): 49-61. Ahmedullah, M., Nayar, M.P. (1999). Red data book of Indian plants, Vol.4 (Peninsular India), Calcutta: Botanical Survey of India. Ahsan, R., Islam, K.M., Bulbul, I.J., Musaddik, M.A. and Haque, E. (2009). Hepatoprotctive activity of methanol extract of some medicinal plants against CCl 4 induced hepatoprotective in rats. European Journal of Scientific Research, 37 (2): 302-310.

Transcript of BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... ·...

Page 1: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

BIBLIOGRAPHY

Aarsland A and Wolfe RR (1998) Hepatic secretion of VLDL fatty acids

during stimulated lipogenesis in men J Lipid Res 39(6) 1280ndash6

Abdel-Hameed and El-Sayed Saleh (2009) Total phenolic contents and free

radical scavenging activity of certain Egyptian Ficus species leaf samples

Food Chemistry 114 1271ndash1277

Abdullahil BM Robiul I Sharifun NI Khurshi AHM Bytul M

Sadik G and Mondal K (2007) Sub-acute toxicity study of the compound

4-methoxy-6-carboxy-benzofuran isolated from Derris indica ResJMed

Sci 2(2) 106-110

Abu-Elheiga L Matzuk MM Abo-Hashema KA and Wakil S (2001)

J Science 291 2613

Adams LA and Angulo P (2005) Recent concepts in non-alcoholic fatty

liver disease Diabet Med 22 1129ndash33

Adiels M Taskinen MR Packard C Caslake MJ Soro-Paavonen A

and Westerbacka J (2007) Overproduction of large VLDL particles is

driven by increased liver fat content in man Diabetologia 49 755ndash65

Agarwal S and Rao AV (2000) Tomato lycopene and its role in human

health and chronic diseases Canadian Medical Association Journal 163(6)

739minus744

Ahmed MH Byrne CD (2007) Modulation of sterol regulatory element

binding proteins (SREBPs) as potential treatments for non-alcoholic fatty

liver disease (NAFLD) Drug Discovery Today 12740ndash747

Ahmed MM and Zaki NI (2009) Assessment the Ameliorative Effect of

Pomegranate and Rutin on Chlorpyrifos-ethyl-Induced Oxidative Stress in

Rats Nature and Science 7(10) 49-61

Ahmedullah M Nayar MP (1999) Red data book of Indian plants Vol4

(Peninsular India) Calcutta Botanical Survey of India

Ahsan R Islam KM Bulbul IJ Musaddik MA and Haque E (2009)

Hepatoprotctive activity of methanol extract of some medicinal plants

against CCl4 induced hepatoprotective in rats European Journal of Scientific

Research 37 (2) 302-310

Ai J Wang N Yang M Du ZM Zhang YC and Yang BF (2005)

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Al-Fatimi M Wurster M Schroumlder G and Lindequist U (2007)

Antioxidant antimicrobial and cytotoxic activities of selected medicinal

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Al-Ghamdi MS (2001) The anti-inflammatory analgesic and antipyretic

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Allard JP Aghdassi E Mohammed S Raman M Avand G Arendt

BM Jalali P Kandasamy T Prayitno N Sherman M Guindi M Ma

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Anand Khakhar Hindu April 25th 2010

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Anstee QM Goldin RD (2006) Mouse models in non-alcoholic fatty

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(Eds) Pregman Press

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Cakir A Ahmet Yildirim MA Duru M E HArmandar M and Kazaz

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Cave M Deaciuc I Mendez C Song Z Joshi-Barve S and Barve S

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nutrition J Nutr Biochem 18 184ndash195

Ceriello A (2000) Oxidative stress and glycemic regulation Metabolism

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Ceriello A (2003) New insights on oxidative stress and diabetic

complication may lead to a causal antioxidant therapy Diabetes Care 26

1589ndash1596

Ceylan-Isik AF Fliethman RM Wold LE and Ren J (2008) Herbal

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Charlton M Sreekumar R Rasmussen D Lindor K and Nair KS

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Chatterjee TK (2000) Medicinal plants with hepatoprotective properties in

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Edition (Books amp Allied (P) Ltd Calcutta) 135

Chaudary SA Tayyab M and Ditta A (1996) Serum Lipid Profile in

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Cult 70 (3-4) 142-5

Cheikh Rouhou S Besbes S Hentati B Blecker C Deroanne C and

Attia H (2007) Nigella sativa L chemical composition and

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Cheikh Rouhou S Hentati B Besbes S Blecker C Deroanne C and

Attia H (2006) Chemical composition and lipid fraction characteristics of

Aleppo Pine (Pinus halepensis Mill) seeds cultivated in Tunisia Food

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Chiang MY Chang JY Kuo CC Chang CY and Kuo YH (2005)

Cytotoxic triterpenes from the aerial roots of Ficus microcarpa

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Choudhury J and Sanyal AJ (2004) Insulin resistance and the

pathogenesis of non-alcoholic fatty liver disease Clin Liver Dis 8575ndash94

Cioffi G Dal Piaz F De Caprariis P Sanego R Marzocco S Autore

G and De Tommasi N (2006) Antiproliferative triterpene saponins from

Entada africana Journal of Natural Products 69 1323ndash1329

Clarke SD (2001) Nonalcoholic steatosis and steatohepatitis I Molecular

mechanism for polyunsaturated fatty acid regulation of gene transcription

Am J Physiol Gastrointest Liver Physiol 281 G865ndash869

Comalada MD CAmuesco S Sierra I Ballester J Xaus J Galvez and

Zarzuelo (2005) In vivo quercitin anti-inflammatory effect involves release

of quercitin which inhibits inflammation through down-regulation of the Nf-

Kappa B pathway Eur J Immunol 35 584-592

Cook NC and Samman S (1996) Flavonoids ndash chemistry metabolism

cardioprotective effects and dietary sources Nutr Biochem 7 66-76

Corbett JW Harwood H J (2007) Jr Rec Pat Cardiovasc Drug Discov

2 162

Cotgreave I Moldeus P and Orrenius S (1988) Host biochemical

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189-212

Craig WJ (1970) Health-promoting properties of common herbs Am J

Clin Nutr 70(3 suppl) 491Sndash499S

Crespo J Cayon A and Pons-Romero F (2004) Pathogenesis of non-

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Cronan JE Jr and Waldrop GL (2002) Multi-subunit acetyl-CoA

carboxylases Prog Lipid Res 41 407ndash435

Crook MA (2006) Clinical chemistry and metabolic medicine 7th

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Hodder Arnold London 426

Cross CE Halliwell B Borish ET Pryor WA Ames BN Saul RL

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Cross CE Reznick AZ Packer L Davis PZ SuzukiYJ and

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Society of plant physiology 1250-1318

Cui W Chen SL and Hu KQ (2010) Quantification and mechanisms of

oleic acid induced steatosis in HepG2 cells Am J Transl Res 2 95-104

Czakoacute L Szabolcs A Vajda A Csaacuteti S Venglovecz V and

Rakonczay Z (2007) Hyperlipidaemia induced by a cholesterol-rich diet

aggravates necrotizing pancreatitis in rats European Journal of

Pharmacology 572 74ndash81

Daba MH and Abdel-Rahman MS (1998) Hepatoprotective activity of

thymoquinone in isolated rat hepatocytes Toxicology Letters 95 23ndash29

Dandona P Aljada A Chaudhuri A Mohanty P and Rajesh G (2004)

Metab Syndr RelatDisord 2 2e8

Daniel RS Mathew BC Devi KS and Augusti KT (1998) Antioxidant

effect of two flavonoids from the bark of Ficus bengalensis Linn in

hyperlipidemic rats Indian Journal of Experimental Biology 36 902ndash906

Das S Vasisht S Das SN and Srivastava LM (2000) Correlation

between total antioxidant status and lipid peroxidation in

hypercholesterolaemia Current Science 78 486ndash487

Das U (2002) A radical approach to cancer Med Sci Monit 8 RA79ndash92

Day CP James O (1998) Steatohepatitis a tale of two hits

Gastroenterology 114 842-5

De Jong N Plat J and Mensink RP (2003) Metabolic effects of plant

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Deladino L Anbinder PS Navarro AS and Martino MN (2008)

Encapsulation of natural antioxidants extracted from Ilex paraguariensis

Carbohydrate Polymers 71 126ndash134

Delaquis P Stanich K and Toivonen P (2005) Effect of pH on the

inhibition of Listeria spp by vanillin and vanillic acid Journal of Food

Protein 68 1472-1476

Delazar A Reid RG and Sarker SD (2004) GC-MS analysis of the

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of Natural compounds 40(1) 4-27

Denechaud PD Dentin R Girard J and Postic C (2008) Role of

ChREBP in hepatic steatosis and insulin resistance FEBS Lett 58268ndash73

Deng J Wangyuan Cheng and Guangzhong Yang (2011) A novel

antioxidant activity index (AAU) for natural products using the DPPH assay

Food Chemistry 125 1430ndash1435

Dentin R Girard J and Postic C (2005) Carbohydrate responsive element

binding protein (ChREBP) and sterol regulatory element binding protein-1c

(SREBP-1c) two key regulators of glucose metabolism and lipid synthesis in

liver Biochime 8781ndash6

Devasagayam TPA Kamat JP and Sreejayan N (2001) Antioxidant

action of curcumin In micronutrients and health Molecular Biological

Mechanisms (eds Nesartnam K And Packer L) AOCS Press Champaign

IL USA 42-59

Di Carlo G Mascolo N and Izzo AA (1999) Flavonoids old and new

aspects of a class of natural therapeutic drugs Life Sci 65 337-53

Di Majo D Giammanco M La Guardia M Tripoli E Giammanco S

and Finotti E (2005) Flavonones in citrus fruit Structure-antioxidant

activity relationships Food Research International 38 1161-1166

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overexpression Arterioscler Thromb Vasc Biol 25 90ndash95

Diehl AM (2003) Non-alcoholic steatohepatitis pathogenesis In Arroyo

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Diseases Barcelona Medicina STM Editores 227-32

Dini I Tenore GC and Dini A (2009) Saponins in Ipomoea batatas

tubers isolation characterization quantification and antioxidant properties

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Dinnis TCP Maderia VM and Almeida LM (1994) Action of phenolic

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membrane lipid peroxidation and as peroxyl radical scavengers Arch

Biochem Biophys 315 161-169

Diraison F and Beylot M (1998) Role of human liver lipogenesis and

reesterification in triglycerides secretion and in FFA reesterification Am J

Physiol 274 E321ndashE327

Domenicali M Vendemiale G Serviddio G Grattagliano I Pertosa

AM Nardo B Principe A Viola A Trevisani F Altomare E

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ischemia-reperfusion is modulated by nutritional status Dig Liver Dis 37

689ndash697

Donnelly KL Smith CI Schwarzenberg SJ Jessurun J Boldt MD

and Parks EJ (2005) Sources of fatty acids stored in liver and secreted via

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Clinical Investigations 115(5) 1343ndash1351

Doreswamy R and Sharma D (1995) Plant drugs for liver disorders

management Indian Drugs 32 139

Doumas BT (1975) Clin Chem 21 1159

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fatty liver disease World J Gastroenterol 13 4539ndash4550

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Eisenberg M Kessler RC Foster C Norlock FE Calkins DR and

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Prevalence costs and patterns of use New Engl J Med 32 246-252

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radical scavenging properties of lignans Organic and Bimolecular

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Ekstedt M Franzeacuten LE Mathiesen UL Thorelius L Holmqvist M

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NAFLD and elevated liver enzymes Hepatology 44 865ndash873

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NADPH supported oxidase activity and lipid peroxidation dependent on

ethanol-inducible cytochrome P-450 (P-450 IIE1) Biochem Pharmacol 38

1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

protects against induced hepatotoxicity and improves serum lipid profile in

rats Arzneimittelforschung 50 832ndash836

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Emery MG Fisher JM and Chien JY (2003) CYP2E1 activity before

and after weight loss in morbidly obese subjects with nonalcoholic fatty

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

expression of hepatic CYP2E1 and CYP4A in obese diabetic obob mice

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biochemistry of 4-hydroxynonenal malonaldehyde and related aldehydes

Free Radical Biology amp Medicine 11 (1) 81ndash128

Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fan JG Zhu J and Li XJ (2005) Fatty liver and the metabolic syndrome

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

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Ferannini E Natalie A and Bell P (1997)Insulin resistance and

hypersecretion in obesity J Clin Invest 100 1166

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during plant stress Proceedings of the Royal Society of Edinburgh 102B

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inducers of lipid peroxidation in tissue slices Free Radical Biology and

Medicine 3 119-123

Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

liver chemistry tests Gasteroenteerology 123 1367-1384

Grill V and Bjoumlrklund A (2009) Impact of metabolic abnormalities for

beta cell function clinical significance and underlying mechanisms Mol

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improvement for nutritional and health benefits Curr Opin Biotechnol 13

508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

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antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

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Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

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FRAP assay Nutrition Research 23 1719ndash1726

Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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superoxide in inflammation and immune regulation Journal of Physiology

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action of medicinal herbs from Ghana Thonningia sanguine on

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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and hepatoprotective effects of silibinin in a rat model of nonalcoholic

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Halliwell B (1993) The role of oxygen radicals in human disease with

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Halliwell B (1994) Free radicals antioxidants and human disease

curiosity cause or consequence Lancet 344 721ndash724

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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antioxidants in biological systems Free Radical Biol Med 18 125ndash126

Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

characterization of antioxidant Food Chem Toxicol 33 601-617

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

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Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harbrone JBC (1973) Phytochemical methods Chapman and Hall

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

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and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

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Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

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some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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Hedge JE and Hofreiter BT (1962) Detremination of reducing sugars

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

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and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

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a causal role in multiple forms of insulin resistance Nature 440944ndash8

httpclinicaltrialsgovct2showNCT00065676intrfrac1422quercetin

22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

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Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

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King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

al The role of oxidative stress in non-alcoholic steatohepatitis Clin Chim

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Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Medicinal Chemistry 24(2) 395minus405

Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

and Dosso M (2004) Traditional medicine in North Cocircte-DlsquoIvoire

Screening of 50 medicinal plants for antibacterial activity Journal of

Ethnopharmacology 93 43ndash49

Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

feeding results in higher serum alanine aminotransferase and increased

insulin resistance compared with a standard murine high-fat diet Am J

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Korchak HM (1962) Regulation of hepatic lipogenesis Tufts Folia Med

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

of chemical composition and antifungal and antioxidant activities of the

essential oils from three Turkish Artemisia species Journal of Agricultural

and Food Chemistry 53 1408ndash1416

Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

in patients with nonalcoholic steatohepatitis Journal of Clinical

Gastroenterology 37 177ndash182

Kotani K Peroni OD Minokoshi Y Boss O and Kahn BB (2004)

GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

Koteish A and Diehl AM (2002) Animal models of steatohepatitis Best

Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not

ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

Kowdley KV (2000) Ursodeoxycholic acid therapy in hepatobiliary

disease Am J Med 108 481ndash486

Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

resistance in high-fat-fed rats Diabetes 40 1397 ndash 1403

Kresge N Simoni RD and Hill RL (2006) Forty years of superoxide

dismutase research the work of irwin fridovich [J] J Biol Chem 281(22)

17-19

Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

(2007) Antihyperglycemic and antilipidperoxidative effects of Ficus

racemosa (Linn) bark extracts in alloxan induced diabetic rats J Med Sci

7 330-338

Kroumltz F Sohn HY and Gloe T (2002) Oxidase-dependent platelet

superoxide anion release incrj5eases platelet recruitment Blood 100 917-

924

Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

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6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

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cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

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Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

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of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

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metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

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Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Lipids 99 11-19

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

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Rheediinosides A and B two antiproliferative and antioxidant triterpene

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Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

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(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

rich tomato juice and lycopene supplements The FASEB Journal 12(4)

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

oxygen and nitrogen species and glutathione key players in the legume-

Rhizobium symbiosis Journal of Experimental Botany 57 (8) 1769-76

Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

Sci 5 445-459

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

Ethanopharmacology 91 99-104

Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

Reitman S Frankel S (1957) Amer JClin Path 2856

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

Med 20 933ndash956

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

Brain Res 900 128-136

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dcrease in lipid peroxidation after vitamin E dietary supplementation in

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

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fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

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Coll Nutr 24 376e384

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the hamster The Journal of Clinical Investigation 81 300ndash309

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

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Ethanopharmacol 112 514-524

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Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

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pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

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varieties cumin black cumin and bitter cumin on antioxidant systems Eur

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Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

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activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

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Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

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Trivedi CP Shinde S and Sharma RC (1969) Preliminary

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(Gular) Indian J Med Res 57 (6) 1070ndash1074

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Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

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Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

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organs of rats exposed to lead Indian J Pharm 33 185-191

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JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

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human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

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Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

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Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

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Brunt EM (2001) Nonalcoholic steatohepatitis definition and pathology

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(Eds) Pregman Press

Bu-Elheiga L Brinkley WR Zhong L Chirala SS Woldegiorgis G

and Wakil SJ (2000) The subcellular localization of acetyl-CoA

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Bytul MR Abdul MA Rahman MM Robiul MI and Shah MAB

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114

Cai Y Luo Q Sun M and Corke H (2004) Antioxidant activity and

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Cakir A Ahmet Yildirim MA Duru M E HArmandar M and Kazaz

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Caponio F Alloggio V and Gomes T (1999) Phenolic compounds of

virgin olive oil influence of paste preparation techniques Food Chemistry

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Carr TP Andresen CJ and Rudel LL (1993) Enzymatic determination

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Clinical Biochemistry 26 39ndash42

Cases S Novak S Zheng YW Myers HM Lear SR and Sande E

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Cave M Deaciuc I Mendez C Song Z Joshi-Barve S and Barve S

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nutrition J Nutr Biochem 18 184ndash195

Ceriello A (2000) Oxidative stress and glycemic regulation Metabolism

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Ceriello A (2003) New insights on oxidative stress and diabetic

complication may lead to a causal antioxidant therapy Diabetes Care 26

1589ndash1596

Ceylan-Isik AF Fliethman RM Wold LE and Ren J (2008) Herbal

and traditional Chinese medicine for the treatment of cardiovascular

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Chalasani N Deeg MA and Crabb DW (2004) Systemic levels of lipid

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Charlton M (2004) Nonalcoholic Fatty Liver Disease a Review of Current

Understanding and Future Impact Clin Gastroenterol Hepatol 21048-1058

Charlton M Sreekumar R Rasmussen D Lindor K and Nair KS

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Hepatology 35898ndash904

Chatterjee IB and Nandi A (1991) Ascorbic acid a scavenges of

oxyradicals Indian J Biochem Biophys 28 233-236

Chatterjee MD and Shinde R (1998) Liver function tests In text book of

Medical Biochemistry Chap34 Delhi Lordson Publishers 3 904-927

Chatterjee TK (2000) Medicinal plants with hepatoprotective properties in

Herbal Options 3rd

Edition (Books amp Allied (P) Ltd Calcutta) 135

Chaudary SA Tayyab M and Ditta A (1996) Serum Lipid Profile in

Albino Rats Fed on Atherogenic Supplemented Palm Oil Diet and Nigella

sativa Thesis Deptt Path Post Grad Med Inst Lahore Pakistan

Chaudhuri P Maji T and Ray KD (2004) Cancer and Radiotherapy Sci

Cult 70 (3-4) 142-5

Cheikh Rouhou S Besbes S Hentati B Blecker C Deroanne C and

Attia H (2007) Nigella sativa L chemical composition and

physicochemical characteristics of lipid fraction Food Chemistry 101 673ndash

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Cheikh Rouhou S Hentati B Besbes S Blecker C Deroanne C and

Attia H (2006) Chemical composition and lipid fraction characteristics of

Aleppo Pine (Pinus halepensis Mill) seeds cultivated in Tunisia Food

Science and Technology International 15 (5) 407ndash416

Chiang MY Chang JY Kuo CC Chang CY and Kuo YH (2005)

Cytotoxic triterpenes from the aerial roots of Ficus microcarpa

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Chipault JR (1962) In Lundberg WO (Ed) Autooxidation and

Antioxidants vol 2 Interscience New York pp 477ndash542

Chopra RN Nayar SL Chopra IC (1956) Glossary of Indian

Medicinal Plants CSIR New Delhi India pp175

Choudhury J and Sanyal AJ (2004) Insulin resistance and the

pathogenesis of non-alcoholic fatty liver disease Clin Liver Dis 8575ndash94

Cioffi G Dal Piaz F De Caprariis P Sanego R Marzocco S Autore

G and De Tommasi N (2006) Antiproliferative triterpene saponins from

Entada africana Journal of Natural Products 69 1323ndash1329

Clarke SD (2001) Nonalcoholic steatosis and steatohepatitis I Molecular

mechanism for polyunsaturated fatty acid regulation of gene transcription

Am J Physiol Gastrointest Liver Physiol 281 G865ndash869

Comalada MD CAmuesco S Sierra I Ballester J Xaus J Galvez and

Zarzuelo (2005) In vivo quercitin anti-inflammatory effect involves release

of quercitin which inhibits inflammation through down-regulation of the Nf-

Kappa B pathway Eur J Immunol 35 584-592

Cook NC and Samman S (1996) Flavonoids ndash chemistry metabolism

cardioprotective effects and dietary sources Nutr Biochem 7 66-76

Corbett JW Harwood H J (2007) Jr Rec Pat Cardiovasc Drug Discov

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Cotgreave I Moldeus P and Orrenius S (1988) Host biochemical

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Craig WJ (1970) Health-promoting properties of common herbs Am J

Clin Nutr 70(3 suppl) 491Sndash499S

Crespo J Cayon A and Pons-Romero F (2004) Pathogenesis of non-

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Cronan JE Jr and Waldrop GL (2002) Multi-subunit acetyl-CoA

carboxylases Prog Lipid Res 41 407ndash435

Crook MA (2006) Clinical chemistry and metabolic medicine 7th

edition

Hodder Arnold London 426

Cross CE Halliwell B Borish ET Pryor WA Ames BN Saul RL

McCord JM and Harman D (1987) Oxygen radicals and human disease

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Cross CE Reznick AZ Packer L Davis PZ SuzukiYJ and

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Free Radical Research Communications 15 347-352

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Biochemistry and molecular biology of plants Roclville MD American

Society of plant physiology 1250-1318

Cui W Chen SL and Hu KQ (2010) Quantification and mechanisms of

oleic acid induced steatosis in HepG2 cells Am J Transl Res 2 95-104

Czakoacute L Szabolcs A Vajda A Csaacuteti S Venglovecz V and

Rakonczay Z (2007) Hyperlipidaemia induced by a cholesterol-rich diet

aggravates necrotizing pancreatitis in rats European Journal of

Pharmacology 572 74ndash81

Daba MH and Abdel-Rahman MS (1998) Hepatoprotective activity of

thymoquinone in isolated rat hepatocytes Toxicology Letters 95 23ndash29

Dandona P Aljada A Chaudhuri A Mohanty P and Rajesh G (2004)

Metab Syndr RelatDisord 2 2e8

Daniel RS Mathew BC Devi KS and Augusti KT (1998) Antioxidant

effect of two flavonoids from the bark of Ficus bengalensis Linn in

hyperlipidemic rats Indian Journal of Experimental Biology 36 902ndash906

Das S Vasisht S Das SN and Srivastava LM (2000) Correlation

between total antioxidant status and lipid peroxidation in

hypercholesterolaemia Current Science 78 486ndash487

Das U (2002) A radical approach to cancer Med Sci Monit 8 RA79ndash92

Day CP James O (1998) Steatohepatitis a tale of two hits

Gastroenterology 114 842-5

De Jong N Plat J and Mensink RP (2003) Metabolic effects of plant

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Deladino L Anbinder PS Navarro AS and Martino MN (2008)

Encapsulation of natural antioxidants extracted from Ilex paraguariensis

Carbohydrate Polymers 71 126ndash134

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antioxidant activity index (AAU) for natural products using the DPPH assay

Food Chemistry 125 1430ndash1435

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NADPH supported oxidase activity and lipid peroxidation dependent on

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

protects against induced hepatotoxicity and improves serum lipid profile in

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

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Ferannini E Natalie A and Bell P (1997)Insulin resistance and

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Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

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beta cell function clinical significance and underlying mechanisms Mol

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508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

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antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

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disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

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Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

Harada N Oda Z Hara Y Fujinami K Okawa M Ohbuchi K

Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harborne JB (1973) Phytochemical methods Chapman and Hall New

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Harbrone JBC (1973) Phytochemical methods Chapman and Hall

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

JG Magee WP Dalvie DK Soliman VF Martin WH Mularski CJ

and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

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some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

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Biochem Biophys 395 137-145

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388-389

Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

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22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

MJ and Weinrauch Y (2008) Reactive nitrogen species contribute to

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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Johnson IT (2004) New approaches to the role of diet in the prevention of

cancers of the alimentary tract Mutation Research 551(1ndash2) 9minus28

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

Alonso-Villaverde C Aragones G Claria J and Camps J (2007) The

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193ndash202

Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

Kiyoshi Mizuguchi (2009) Suppression of hepatic fat accumulation by

highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

diet Biochimica et Biophysica Acta 1791 281ndash288

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spectrophotometric assay of superoxide dismutase Indian J

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

Koumlnigsrainer I Koumlnigsrainer A Schick F Fritsche A Haumlring HU

and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

59ndash75) London UK Taylor and Francis Press

Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

Experimental 35 655-657

Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

K (2005) Potential of sourdough for healthier cereal products Trends Food

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radiation on red cell membrane and intracellular oxidative defense systems

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Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

Keeling CI and Bohlmann J (2006) Genes enzymes and chemicals of

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against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

Ipomoea mauritiana 1 22-30

Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

oxidative damage response in Wistar rats Life Sciences 77 1194ndash1210

Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

Ursodeoxycholic acid and atorvastin in the treatment of non-alcoholic

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Klichko VI Radyuk SN and Orr WC (2004) Profiling catalase gene

expression in Drosophilla melanogastr during development and aging

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Knight JA (2000) Review Free radicals antioxidants and the immune

system Ann Clin Lab Sci 30 145-158

Knowles JR (1989) The mechanism of biotin-dependent enzymes Ann

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Acta (2011) doi101016jcca201104013

Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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supplementation retards early progression of arteriosclerosis in heart

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

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Progress in Lipid Research 48 1e26

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relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

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preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

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Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

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Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

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Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

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Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

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Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

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and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

Seeds Food Chem 106 760-766

Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

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carotenoids are more bioaccessible from fruits than dark green vegetables

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Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

Portois L and Chardigny JM (2006) Alteration of adipocyte metabolism

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Okada Y Shibata S Ikekawa T Javellana AMJ and Kamo O (1987)

Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

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Acta Chromatographica 19 253-269

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convenient substrate for determination and study of L-and D-glutamyl trans

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Scientific Society Press Tokyo 241-251

Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

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tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

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Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

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Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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Biophys Acta 1487 190-200

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

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Page 3: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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(Eds) Pregman Press

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Burits M and Bucar F (2000) Antioxidant activity of Nigella sativa

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Bytul MR Abdul MA Rahman MM Robiul MI and Shah MAB

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Cai Y Luo Q Sun M and Corke H (2004) Antioxidant activity and

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Cakir A Ahmet Yildirim MA Duru M E HArmandar M and Kazaz

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flavonoids in plant samples Lancet 179

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Caponio F Alloggio V and Gomes T (1999) Phenolic compounds of

virgin olive oil influence of paste preparation techniques Food Chemistry

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Carr TP Andresen CJ and Rudel LL (1993) Enzymatic determination

of triglyceride free cholesterol and total cholesterol in tissue lipid extracts

Clinical Biochemistry 26 39ndash42

Cases S Novak S Zheng YW Myers HM Lear SR and Sande E

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acyltransferase Its cloning expression and characterization J Biol Chem

273 26755-26764

Cave M Deaciuc I Mendez C Song Z Joshi-Barve S and Barve S

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nutrition J Nutr Biochem 18 184ndash195

Ceriello A (2000) Oxidative stress and glycemic regulation Metabolism

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Ceriello A (2003) New insights on oxidative stress and diabetic

complication may lead to a causal antioxidant therapy Diabetes Care 26

1589ndash1596

Ceylan-Isik AF Fliethman RM Wold LE and Ren J (2008) Herbal

and traditional Chinese medicine for the treatment of cardiovascular

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Chalasani N Deeg MA and Crabb DW (2004) Systemic levels of lipid

peroxidation and its metabolic and dietary correlates in patients with

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Charlton M (2004) Nonalcoholic Fatty Liver Disease a Review of Current

Understanding and Future Impact Clin Gastroenterol Hepatol 21048-1058

Charlton M Sreekumar R Rasmussen D Lindor K and Nair KS

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Hepatology 35898ndash904

Chatterjee IB and Nandi A (1991) Ascorbic acid a scavenges of

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Chatterjee MD and Shinde R (1998) Liver function tests In text book of

Medical Biochemistry Chap34 Delhi Lordson Publishers 3 904-927

Chatterjee TK (2000) Medicinal plants with hepatoprotective properties in

Herbal Options 3rd

Edition (Books amp Allied (P) Ltd Calcutta) 135

Chaudary SA Tayyab M and Ditta A (1996) Serum Lipid Profile in

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sativa Thesis Deptt Path Post Grad Med Inst Lahore Pakistan

Chaudhuri P Maji T and Ray KD (2004) Cancer and Radiotherapy Sci

Cult 70 (3-4) 142-5

Cheikh Rouhou S Besbes S Hentati B Blecker C Deroanne C and

Attia H (2007) Nigella sativa L chemical composition and

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Cheikh Rouhou S Hentati B Besbes S Blecker C Deroanne C and

Attia H (2006) Chemical composition and lipid fraction characteristics of

Aleppo Pine (Pinus halepensis Mill) seeds cultivated in Tunisia Food

Science and Technology International 15 (5) 407ndash416

Chiang MY Chang JY Kuo CC Chang CY and Kuo YH (2005)

Cytotoxic triterpenes from the aerial roots of Ficus microcarpa

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Chipault JR (1962) In Lundberg WO (Ed) Autooxidation and

Antioxidants vol 2 Interscience New York pp 477ndash542

Chopra RN Nayar SL Chopra IC (1956) Glossary of Indian

Medicinal Plants CSIR New Delhi India pp175

Choudhury J and Sanyal AJ (2004) Insulin resistance and the

pathogenesis of non-alcoholic fatty liver disease Clin Liver Dis 8575ndash94

Cioffi G Dal Piaz F De Caprariis P Sanego R Marzocco S Autore

G and De Tommasi N (2006) Antiproliferative triterpene saponins from

Entada africana Journal of Natural Products 69 1323ndash1329

Clarke SD (2001) Nonalcoholic steatosis and steatohepatitis I Molecular

mechanism for polyunsaturated fatty acid regulation of gene transcription

Am J Physiol Gastrointest Liver Physiol 281 G865ndash869

Comalada MD CAmuesco S Sierra I Ballester J Xaus J Galvez and

Zarzuelo (2005) In vivo quercitin anti-inflammatory effect involves release

of quercitin which inhibits inflammation through down-regulation of the Nf-

Kappa B pathway Eur J Immunol 35 584-592

Cook NC and Samman S (1996) Flavonoids ndash chemistry metabolism

cardioprotective effects and dietary sources Nutr Biochem 7 66-76

Corbett JW Harwood H J (2007) Jr Rec Pat Cardiovasc Drug Discov

2 162

Cotgreave I Moldeus P and Orrenius S (1988) Host biochemical

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189-212

Craig WJ (1970) Health-promoting properties of common herbs Am J

Clin Nutr 70(3 suppl) 491Sndash499S

Crespo J Cayon A and Pons-Romero F (2004) Pathogenesis of non-

alcoholic fatty liver and potential therapeutic targets Gastroenterol Hepatol

27 (Suppl 1) 15-23

Cronan JE Jr and Waldrop GL (2002) Multi-subunit acetyl-CoA

carboxylases Prog Lipid Res 41 407ndash435

Crook MA (2006) Clinical chemistry and metabolic medicine 7th

edition

Hodder Arnold London 426

Cross CE Halliwell B Borish ET Pryor WA Ames BN Saul RL

McCord JM and Harman D (1987) Oxygen radicals and human disease

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Cross CE Reznick AZ Packer L Davis PZ SuzukiYJ and

Halliwell B (1992) Oxidative damage to human plasma proteins by ozone

Free Radical Research Communications 15 347-352

Croteau K Kutchan TM and Leis NG (2000) Natural products

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Biochemistry and molecular biology of plants Roclville MD American

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Cui W Chen SL and Hu KQ (2010) Quantification and mechanisms of

oleic acid induced steatosis in HepG2 cells Am J Transl Res 2 95-104

Czakoacute L Szabolcs A Vajda A Csaacuteti S Venglovecz V and

Rakonczay Z (2007) Hyperlipidaemia induced by a cholesterol-rich diet

aggravates necrotizing pancreatitis in rats European Journal of

Pharmacology 572 74ndash81

Daba MH and Abdel-Rahman MS (1998) Hepatoprotective activity of

thymoquinone in isolated rat hepatocytes Toxicology Letters 95 23ndash29

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

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Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

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508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

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antioxidant activity of a triterpenoid glycoside isolated from the berries of

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Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

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Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

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and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

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of broiler chicks Egypt Poult Sci 24 247ndash266

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Conjugates of ursodeoxycholate protect against cytotoxicity of more

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

MJ and Weinrauch Y (2008) Reactive nitrogen species contribute to

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

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spectrophotometric assay of superoxide dismutase Indian J

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

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Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Kaufmann (1999) National products of high pharmacological potency

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Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

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Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

oxidative damage response in Wistar rats Life Sciences 77 1194ndash1210

Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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191

King J (1965b) The dehydrogenase or oxidoreductase-Lactate

dehydrogenase In Practical Clinical Enzymology (Ed Van D) London

Nostrond Company Limited 83

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

Ursodeoxycholic acid and atorvastin in the treatment of non-alcoholic

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system Ann Clin Lab Sci 30 145-158

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Rev Biochem 58 195ndash221

Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Acta (2011) doi101016jcca201104013

Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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supplementation retards early progression of arteriosclerosis in heart

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

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genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Michalak A (2006) Phenolic compounds and their antioxidant activity in

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

formulation in galactosamine induced hepatopathy in rats Indian J Physiol

Pharmacol 44 82-86

Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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1421

Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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Morris GM Goodsell DS Halliday RS Huey R Hart WE Belew

RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

algorithm and an empirical binding free energy function J Comput Chem

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antibiotics as a mechanism of pathogenesis Microbiological and Molecular

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Moss DW and Butterorth PJ (1974) Enzymology and Medicine London

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Mozaffari FS Ghorbani M Babai A and Farzami Sepehr M (2000)

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Mursu J Voutilainen S Nurmi T Tuomainen TP Kurl S and Salonen

JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

411

Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

composition of the fixed and volatile oils of Nigella Sativa L Zeitschrift for

Naturforschung 629-631

Nield and Pearson Burtis CA and Ashwood A (1963) In Text Book of

Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

reperfusion injury Br J Surg 91(2) 184-190

Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

Noguchi N Damiani E Greci L and Niki E (1999) Action of quinolinic

and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

Seeds Food Chem 106 760-766

Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

OConnell OF Ryan L and OBrien NM (2007) Xanthophyll

carotenoids are more bioaccessible from fruits than dark green vegetables

Nutrition Research 27(5) 258minus264

Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

fruits mixtures used in the treatment of diabtes AfrJBiotechnol 7(6) 701-

705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

Portois L and Chardigny JM (2006) Alteration of adipocyte metabolism

in omega3 fatty acid-depleted rats Horm Metab Res 38 789-798

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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chlorogenic acid in the leaves and inflorescences of Prunus serotina Ehrh

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convenient substrate for determination and study of L-and D-glutamyl trans

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Postharvest Biochemistry of Plant Food-Materials in Tropics Japan

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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the hamster The Journal of Clinical Investigation 81 300ndash309

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

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Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

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Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

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Page 4: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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Cave M Deaciuc I Mendez C Song Z Joshi-Barve S and Barve S

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Ceriello A (2000) Oxidative stress and glycemic regulation Metabolism

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Ceriello A (2003) New insights on oxidative stress and diabetic

complication may lead to a causal antioxidant therapy Diabetes Care 26

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Ceylan-Isik AF Fliethman RM Wold LE and Ren J (2008) Herbal

and traditional Chinese medicine for the treatment of cardiovascular

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peroxidation and its metabolic and dietary correlates in patients with

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Charlton M (2004) Nonalcoholic Fatty Liver Disease a Review of Current

Understanding and Future Impact Clin Gastroenterol Hepatol 21048-1058

Charlton M Sreekumar R Rasmussen D Lindor K and Nair KS

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Hepatology 35898ndash904

Chatterjee IB and Nandi A (1991) Ascorbic acid a scavenges of

oxyradicals Indian J Biochem Biophys 28 233-236

Chatterjee MD and Shinde R (1998) Liver function tests In text book of

Medical Biochemistry Chap34 Delhi Lordson Publishers 3 904-927

Chatterjee TK (2000) Medicinal plants with hepatoprotective properties in

Herbal Options 3rd

Edition (Books amp Allied (P) Ltd Calcutta) 135

Chaudary SA Tayyab M and Ditta A (1996) Serum Lipid Profile in

Albino Rats Fed on Atherogenic Supplemented Palm Oil Diet and Nigella

sativa Thesis Deptt Path Post Grad Med Inst Lahore Pakistan

Chaudhuri P Maji T and Ray KD (2004) Cancer and Radiotherapy Sci

Cult 70 (3-4) 142-5

Cheikh Rouhou S Besbes S Hentati B Blecker C Deroanne C and

Attia H (2007) Nigella sativa L chemical composition and

physicochemical characteristics of lipid fraction Food Chemistry 101 673ndash

681

Cheikh Rouhou S Hentati B Besbes S Blecker C Deroanne C and

Attia H (2006) Chemical composition and lipid fraction characteristics of

Aleppo Pine (Pinus halepensis Mill) seeds cultivated in Tunisia Food

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Chiang MY Chang JY Kuo CC Chang CY and Kuo YH (2005)

Cytotoxic triterpenes from the aerial roots of Ficus microcarpa

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Chipault JR (1962) In Lundberg WO (Ed) Autooxidation and

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Chopra RN Nayar SL Chopra IC (1956) Glossary of Indian

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Choudhury J and Sanyal AJ (2004) Insulin resistance and the

pathogenesis of non-alcoholic fatty liver disease Clin Liver Dis 8575ndash94

Cioffi G Dal Piaz F De Caprariis P Sanego R Marzocco S Autore

G and De Tommasi N (2006) Antiproliferative triterpene saponins from

Entada africana Journal of Natural Products 69 1323ndash1329

Clarke SD (2001) Nonalcoholic steatosis and steatohepatitis I Molecular

mechanism for polyunsaturated fatty acid regulation of gene transcription

Am J Physiol Gastrointest Liver Physiol 281 G865ndash869

Comalada MD CAmuesco S Sierra I Ballester J Xaus J Galvez and

Zarzuelo (2005) In vivo quercitin anti-inflammatory effect involves release

of quercitin which inhibits inflammation through down-regulation of the Nf-

Kappa B pathway Eur J Immunol 35 584-592

Cook NC and Samman S (1996) Flavonoids ndash chemistry metabolism

cardioprotective effects and dietary sources Nutr Biochem 7 66-76

Corbett JW Harwood H J (2007) Jr Rec Pat Cardiovasc Drug Discov

2 162

Cotgreave I Moldeus P and Orrenius S (1988) Host biochemical

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Craig WJ (1970) Health-promoting properties of common herbs Am J

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Crespo J Cayon A and Pons-Romero F (2004) Pathogenesis of non-

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27 (Suppl 1) 15-23

Cronan JE Jr and Waldrop GL (2002) Multi-subunit acetyl-CoA

carboxylases Prog Lipid Res 41 407ndash435

Crook MA (2006) Clinical chemistry and metabolic medicine 7th

edition

Hodder Arnold London 426

Cross CE Halliwell B Borish ET Pryor WA Ames BN Saul RL

McCord JM and Harman D (1987) Oxygen radicals and human disease

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Cross CE Reznick AZ Packer L Davis PZ SuzukiYJ and

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Free Radical Research Communications 15 347-352

Croteau K Kutchan TM and Leis NG (2000) Natural products

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Biochemistry and molecular biology of plants Roclville MD American

Society of plant physiology 1250-1318

Cui W Chen SL and Hu KQ (2010) Quantification and mechanisms of

oleic acid induced steatosis in HepG2 cells Am J Transl Res 2 95-104

Czakoacute L Szabolcs A Vajda A Csaacuteti S Venglovecz V and

Rakonczay Z (2007) Hyperlipidaemia induced by a cholesterol-rich diet

aggravates necrotizing pancreatitis in rats European Journal of

Pharmacology 572 74ndash81

Daba MH and Abdel-Rahman MS (1998) Hepatoprotective activity of

thymoquinone in isolated rat hepatocytes Toxicology Letters 95 23ndash29

Dandona P Aljada A Chaudhuri A Mohanty P and Rajesh G (2004)

Metab Syndr RelatDisord 2 2e8

Daniel RS Mathew BC Devi KS and Augusti KT (1998) Antioxidant

effect of two flavonoids from the bark of Ficus bengalensis Linn in

hyperlipidemic rats Indian Journal of Experimental Biology 36 902ndash906

Das S Vasisht S Das SN and Srivastava LM (2000) Correlation

between total antioxidant status and lipid peroxidation in

hypercholesterolaemia Current Science 78 486ndash487

Das U (2002) A radical approach to cancer Med Sci Monit 8 RA79ndash92

Day CP James O (1998) Steatohepatitis a tale of two hits

Gastroenterology 114 842-5

De Jong N Plat J and Mensink RP (2003) Metabolic effects of plant

sterols and stanol J Nutr Biochem 14 362-369

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

protects against induced hepatotoxicity and improves serum lipid profile in

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Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

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Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

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508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

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antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

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Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

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Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

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and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

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of broiler chicks Egypt Poult Sci 24 247ndash266

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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Johnson IT (2004) New approaches to the role of diet in the prevention of

cancers of the alimentary tract Mutation Research 551(1ndash2) 9minus28

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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stability of ethanolic extracts of Holy basil and Galangal Food Chem 92

193ndash202

Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

Kiyoshi Mizuguchi (2009) Suppression of hepatic fat accumulation by

highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

diet Biochimica et Biophysica Acta 1791 281ndash288

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spectrophotometric assay of superoxide dismutase Indian J

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

Koumlnigsrainer I Koumlnigsrainer A Schick F Fritsche A Haumlring HU

and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

59ndash75) London UK Taylor and Francis Press

Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

K (2005) Potential of sourdough for healthier cereal products Trends Food

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radiation on red cell membrane and intracellular oxidative defense systems

Free Radical Research 24 199ndash204

Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

Keeling CI and Bohlmann J (2006) Genes enzymes and chemicals of

teerpenoid diversity in the constitutive and induced defence of coniters

against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

Ipomoea mauritiana 1 22-30

Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

oxidative damage response in Wistar rats Life Sciences 77 1194ndash1210

Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

Ursodeoxycholic acid and atorvastin in the treatment of non-alcoholic

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Klichko VI Radyuk SN and Orr WC (2004) Profiling catalase gene

expression in Drosophilla melanogastr during development and aging

Archives of Insect Biochemisry and Physiology 56 34-50

Knight JA (2000) Review Free radicals antioxidants and the immune

system Ann Clin Lab Sci 30 145-158

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Acta (2011) doi101016jcca201104013

Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Medicinal Chemistry 24(2) 395minus405

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Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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lipid-lowering and insulin-sensitizing actions in the rat Journal of

Ethnopharmacology 94 251ndash259

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mayo Clin Proc 55434-438

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

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genotypes under stress of different concentrations of sucrose and sorbito

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

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JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

411

Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

composition of the fixed and volatile oils of Nigella Sativa L Zeitschrift for

Naturforschung 629-631

Nield and Pearson Burtis CA and Ashwood A (1963) In Text Book of

Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

reperfusion injury Br J Surg 91(2) 184-190

Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

Noguchi N Damiani E Greci L and Niki E (1999) Action of quinolinic

and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

Seeds Food Chem 106 760-766

Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

OConnell OF Ryan L and OBrien NM (2007) Xanthophyll

carotenoids are more bioaccessible from fruits than dark green vegetables

Nutrition Research 27(5) 258minus264

Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

fruits mixtures used in the treatment of diabtes AfrJBiotechnol 7(6) 701-

705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

Portois L and Chardigny JM (2006) Alteration of adipocyte metabolism

in omega3 fatty acid-depleted rats Horm Metab Res 38 789-798

Ohkawa H Ohishi N and Yagi K (1979) Anal Biochem 95 351-358

Okada Y Shibata S Ikekawa T Javellana AMJ and Kamo O (1987)

Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

chlorogenic acid in the leaves and inflorescences of Prunus serotina Ehrh

Acta Chromatographica 19 253-269

Orolowski M and Meister (1963) γ-glutamyl-p-nitroanilide a new

convenient substrate for determination and study of L-and D-glutamyl trans

peptidase activities Biochemica Biophysica Acta 73 679-681

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biological systems In Uritany I Garcia VV Mendoza EM (Ed)

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

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Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

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1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

Reitman S Frankel S (1957) Amer JClin Path 2856

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

Brain Res 900 128-136

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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the hamster The Journal of Clinical Investigation 81 300ndash309

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

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Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

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Page 5: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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Burits M and Bucar F (2000) Antioxidant activity of Nigella sativa

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Cakir A Ahmet Yildirim MA Duru M E HArmandar M and Kazaz

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Cave M Deaciuc I Mendez C Song Z Joshi-Barve S and Barve S

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Ceriello A (2003) New insights on oxidative stress and diabetic

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Chatterjee TK (2000) Medicinal plants with hepatoprotective properties in

Herbal Options 3rd

Edition (Books amp Allied (P) Ltd Calcutta) 135

Chaudary SA Tayyab M and Ditta A (1996) Serum Lipid Profile in

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Cult 70 (3-4) 142-5

Cheikh Rouhou S Besbes S Hentati B Blecker C Deroanne C and

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Cheikh Rouhou S Hentati B Besbes S Blecker C Deroanne C and

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Choudhury J and Sanyal AJ (2004) Insulin resistance and the

pathogenesis of non-alcoholic fatty liver disease Clin Liver Dis 8575ndash94

Cioffi G Dal Piaz F De Caprariis P Sanego R Marzocco S Autore

G and De Tommasi N (2006) Antiproliferative triterpene saponins from

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Clarke SD (2001) Nonalcoholic steatosis and steatohepatitis I Molecular

mechanism for polyunsaturated fatty acid regulation of gene transcription

Am J Physiol Gastrointest Liver Physiol 281 G865ndash869

Comalada MD CAmuesco S Sierra I Ballester J Xaus J Galvez and

Zarzuelo (2005) In vivo quercitin anti-inflammatory effect involves release

of quercitin which inhibits inflammation through down-regulation of the Nf-

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Corbett JW Harwood H J (2007) Jr Rec Pat Cardiovasc Drug Discov

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Cotgreave I Moldeus P and Orrenius S (1988) Host biochemical

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Craig WJ (1970) Health-promoting properties of common herbs Am J

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Cronan JE Jr and Waldrop GL (2002) Multi-subunit acetyl-CoA

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Crook MA (2006) Clinical chemistry and metabolic medicine 7th

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Hodder Arnold London 426

Cross CE Halliwell B Borish ET Pryor WA Ames BN Saul RL

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Cross CE Reznick AZ Packer L Davis PZ SuzukiYJ and

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Cui W Chen SL and Hu KQ (2010) Quantification and mechanisms of

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Czakoacute L Szabolcs A Vajda A Csaacuteti S Venglovecz V and

Rakonczay Z (2007) Hyperlipidaemia induced by a cholesterol-rich diet

aggravates necrotizing pancreatitis in rats European Journal of

Pharmacology 572 74ndash81

Daba MH and Abdel-Rahman MS (1998) Hepatoprotective activity of

thymoquinone in isolated rat hepatocytes Toxicology Letters 95 23ndash29

Dandona P Aljada A Chaudhuri A Mohanty P and Rajesh G (2004)

Metab Syndr RelatDisord 2 2e8

Daniel RS Mathew BC Devi KS and Augusti KT (1998) Antioxidant

effect of two flavonoids from the bark of Ficus bengalensis Linn in

hyperlipidemic rats Indian Journal of Experimental Biology 36 902ndash906

Das S Vasisht S Das SN and Srivastava LM (2000) Correlation

between total antioxidant status and lipid peroxidation in

hypercholesterolaemia Current Science 78 486ndash487

Das U (2002) A radical approach to cancer Med Sci Monit 8 RA79ndash92

Day CP James O (1998) Steatohepatitis a tale of two hits

Gastroenterology 114 842-5

De Jong N Plat J and Mensink RP (2003) Metabolic effects of plant

sterols and stanol J Nutr Biochem 14 362-369

Deladino L Anbinder PS Navarro AS and Martino MN (2008)

Encapsulation of natural antioxidants extracted from Ilex paraguariensis

Carbohydrate Polymers 71 126ndash134

Delaquis P Stanich K and Toivonen P (2005) Effect of pH on the

inhibition of Listeria spp by vanillin and vanillic acid Journal of Food

Protein 68 1472-1476

Delazar A Reid RG and Sarker SD (2004) GC-MS analysis of the

Essential oil from the Oleoresin of Pistacia atlantica var Mutica Chemistry

of Natural compounds 40(1) 4-27

Denechaud PD Dentin R Girard J and Postic C (2008) Role of

ChREBP in hepatic steatosis and insulin resistance FEBS Lett 58268ndash73

Deng J Wangyuan Cheng and Guangzhong Yang (2011) A novel

antioxidant activity index (AAU) for natural products using the DPPH assay

Food Chemistry 125 1430ndash1435

Dentin R Girard J and Postic C (2005) Carbohydrate responsive element

binding protein (ChREBP) and sterol regulatory element binding protein-1c

(SREBP-1c) two key regulators of glucose metabolism and lipid synthesis in

liver Biochime 8781ndash6

Devasagayam TPA Kamat JP and Sreejayan N (2001) Antioxidant

action of curcumin In micronutrients and health Molecular Biological

Mechanisms (eds Nesartnam K And Packer L) AOCS Press Champaign

IL USA 42-59

Di Carlo G Mascolo N and Izzo AA (1999) Flavonoids old and new

aspects of a class of natural therapeutic drugs Life Sci 65 337-53

Di Majo D Giammanco M La Guardia M Tripoli E Giammanco S

and Finotti E (2005) Flavonones in citrus fruit Structure-antioxidant

activity relationships Food Research International 38 1161-1166

Didion SP and Faraci FM (2005) Ceramide-induced impairment of

endothelial function is prevented by CuZn superoxide dismutase

overexpression Arterioscler Thromb Vasc Biol 25 90ndash95

Diehl AM (2003) Non-alcoholic steatohepatitis pathogenesis In Arroyo

V Forns X Garcia-Pagan JC et al eds Progress in the Treatment of Liver

Diseases Barcelona Medicina STM Editores 227-32

Dini I Tenore GC and Dini A (2009) Saponins in Ipomoea batatas

tubers isolation characterization quantification and antioxidant properties

Food Chemistry 113 411ndash419

Dinnis TCP Maderia VM and Almeida LM (1994) Action of phenolic

derivaties (acetaminophen salicylate and 5-aminosalicylate) as inhibitors of

membrane lipid peroxidation and as peroxyl radical scavengers Arch

Biochem Biophys 315 161-169

Diraison F and Beylot M (1998) Role of human liver lipogenesis and

reesterification in triglycerides secretion and in FFA reesterification Am J

Physiol 274 E321ndashE327

Domenicali M Vendemiale G Serviddio G Grattagliano I Pertosa

AM Nardo B Principe A Viola A Trevisani F Altomare E

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ischemia-reperfusion is modulated by nutritional status Dig Liver Dis 37

689ndash697

Donnelly KL Smith CI Schwarzenberg SJ Jessurun J Boldt MD

and Parks EJ (2005) Sources of fatty acids stored in liver and secreted via

lipoproteins in patients with nonalcoholic fatty liver disease Journal of

Clinical Investigations 115(5) 1343ndash1351

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fatty liver disease World J Gastroenterol 13 4539ndash4550

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Prevalence costs and patterns of use New Engl J Med 32 246-252

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radical scavenging properties of lignans Organic and Bimolecular

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Ekstedt M Franzeacuten LE Mathiesen UL Thorelius L Holmqvist M

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NAFLD and elevated liver enzymes Hepatology 44 865ndash873

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NADPH supported oxidase activity and lipid peroxidation dependent on

ethanol-inducible cytochrome P-450 (P-450 IIE1) Biochem Pharmacol 38

1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

protects against induced hepatotoxicity and improves serum lipid profile in

rats Arzneimittelforschung 50 832ndash836

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Emery MG Fisher JM and Chien JY (2003) CYP2E1 activity before

and after weight loss in morbidly obese subjects with nonalcoholic fatty

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

expression of hepatic CYP2E1 and CYP4A in obese diabetic obob mice

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biochemistry of 4-hydroxynonenal malonaldehyde and related aldehydes

Free Radical Biology amp Medicine 11 (1) 81ndash128

Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fan JG Zhu J and Li XJ (2005) Fatty liver and the metabolic syndrome

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

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Ferannini E Natalie A and Bell P (1997)Insulin resistance and

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during plant stress Proceedings of the Royal Society of Edinburgh 102B

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inducers of lipid peroxidation in tissue slices Free Radical Biology and

Medicine 3 119-123

Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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body fat Physiol Behav 94 164ndash8

Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

liver chemistry tests Gasteroenteerology 123 1367-1384

Grill V and Bjoumlrklund A (2009) Impact of metabolic abnormalities for

beta cell function clinical significance and underlying mechanisms Mol

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improvement for nutritional and health benefits Curr Opin Biotechnol 13

508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

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antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

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Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

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activities of peel pulp and seed fractions of common fruits as determined by

FRAP assay Nutrition Research 23 1719ndash1726

Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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superoxide in inflammation and immune regulation Journal of Physiology

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action of medicinal herbs from Ghana Thonningia sanguine on

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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and hepatoprotective effects of silibinin in a rat model of nonalcoholic

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Halliwell B (1993) The role of oxygen radicals in human disease with

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Halliwell B (1994) Free radicals antioxidants and human disease

curiosity cause or consequence Lancet 344 721ndash724

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Halliwell B (2000) Why and how should we measure oxidative DNA

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Halliwell B (2001) Role of free radicals in the neurodegenerative diseases

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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Halliwell B (2006) Reactive species and antioxidants Redox biology is a

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antioxidants in biological systems Free Radical Biol Med 18 125ndash126

Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

characterization of antioxidant Food Chem Toxicol 33 601-617

Halliwell B Gutteridge JM and Cross CE (1992) Free radicals

antioxidants and human disease where are we now J Lab Clin Med 119

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

method a simple test tube assay for determination of rate constants for

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Handa SS Sharma A and Charaborti KK (1986) Natural products and

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

Harada N Oda Z Hara Y Fujinami K Okawa M Ohbuchi K

Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harbrone JBC (1973) Phytochemical methods Chapman and Hall

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

JG Magee WP Dalvie DK Soliman VF Martin WH Mularski CJ

and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

treatment of metabolic syndrome Curr Opin Investig Drugs 5 283ndash289

Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

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some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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Hedge JE and Hofreiter BT (1962) Detremination of reducing sugars

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388-389

Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

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and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

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Houstis N Rosen ED Lander ES (2006) Reactive oxygen species have

a causal role in multiple forms of insulin resistance Nature 440944ndash8

httpclinicaltrialsgovct2showNCT00065676intrfrac1422quercetin

22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

Koumlnigsrainer I Koumlnigsrainer A Schick F Fritsche A Haumlring HU

and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

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Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

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Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

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King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

al The role of oxidative stress in non-alcoholic steatohepatitis Clin Chim

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Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Medicinal Chemistry 24(2) 395minus405

Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

and Dosso M (2004) Traditional medicine in North Cocircte-DlsquoIvoire

Screening of 50 medicinal plants for antibacterial activity Journal of

Ethnopharmacology 93 43ndash49

Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

feeding results in higher serum alanine aminotransferase and increased

insulin resistance compared with a standard murine high-fat diet Am J

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Korchak HM (1962) Regulation of hepatic lipogenesis Tufts Folia Med

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

of chemical composition and antifungal and antioxidant activities of the

essential oils from three Turkish Artemisia species Journal of Agricultural

and Food Chemistry 53 1408ndash1416

Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

in patients with nonalcoholic steatohepatitis Journal of Clinical

Gastroenterology 37 177ndash182

Kotani K Peroni OD Minokoshi Y Boss O and Kahn BB (2004)

GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

Koteish A and Diehl AM (2002) Animal models of steatohepatitis Best

Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not

ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

Kowdley KV (2000) Ursodeoxycholic acid therapy in hepatobiliary

disease Am J Med 108 481ndash486

Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

resistance in high-fat-fed rats Diabetes 40 1397 ndash 1403

Kresge N Simoni RD and Hill RL (2006) Forty years of superoxide

dismutase research the work of irwin fridovich [J] J Biol Chem 281(22)

17-19

Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

(2007) Antihyperglycemic and antilipidperoxidative effects of Ficus

racemosa (Linn) bark extracts in alloxan induced diabetic rats J Med Sci

7 330-338

Kroumltz F Sohn HY and Gloe T (2002) Oxidase-dependent platelet

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924

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

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6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

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Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

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McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

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Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

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Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

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(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

rich tomato juice and lycopene supplements The FASEB Journal 12(4)

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

oxygen and nitrogen species and glutathione key players in the legume-

Rhizobium symbiosis Journal of Experimental Botany 57 (8) 1769-76

Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

Sci 5 445-459

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

Ethanopharmacology 91 99-104

Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

Reitman S Frankel S (1957) Amer JClin Path 2856

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

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polyunsaturated fatty acids J Hepatol 49 262ndash273

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Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

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Ethanopharmacol 112 514-524

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Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

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pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

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varieties cumin black cumin and bitter cumin on antioxidant systems Eur

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Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

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activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

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Trivedi CP Shinde S and Sharma RC (1969) Preliminary

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(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

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organs of rats exposed to lead Indian J Pharm 33 185-191

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JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

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human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

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Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

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Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

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Daniel RS Mathew BC Devi KS and Augusti KT (1998) Antioxidant

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Day CP James O (1998) Steatohepatitis a tale of two hits

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Denechaud PD Dentin R Girard J and Postic C (2008) Role of

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Deng J Wangyuan Cheng and Guangzhong Yang (2011) A novel

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Food Chemistry 125 1430ndash1435

Dentin R Girard J and Postic C (2005) Carbohydrate responsive element

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Devasagayam TPA Kamat JP and Sreejayan N (2001) Antioxidant

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Di Majo D Giammanco M La Guardia M Tripoli E Giammanco S

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reesterification in triglycerides secretion and in FFA reesterification Am J

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Domenicali M Vendemiale G Serviddio G Grattagliano I Pertosa

AM Nardo B Principe A Viola A Trevisani F Altomare E

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689ndash697

Donnelly KL Smith CI Schwarzenberg SJ Jessurun J Boldt MD

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Eisenberg M Kessler RC Foster C Norlock FE Calkins DR and

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Ekstedt M Franzeacuten LE Mathiesen UL Thorelius L Holmqvist M

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

expression of hepatic CYP2E1 and CYP4A in obese diabetic obob mice

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Free Radical Biology amp Medicine 11 (1) 81ndash128

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Fan JG Zhu J and Li XJ (2005) Fatty liver and the metabolic syndrome

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

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Flora SJ (2007) Role of free radicals and antioxidants in health and disease

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Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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body fat Physiol Behav 94 164ndash8

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and oxidative stress in rats Eur J Clin Invest 38 523-530

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

liver chemistry tests Gasteroenteerology 123 1367-1384

Grill V and Bjoumlrklund A (2009) Impact of metabolic abnormalities for

beta cell function clinical significance and underlying mechanisms Mol

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improvement for nutritional and health benefits Curr Opin Biotechnol 13

508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

Guumllccedilin I Mshvildadze VA Gepdiremen A and Elias R (2006) The

antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

Research 20 130ndash134

Gulcin Buyukokuroglu ME Oktay M and Kufrevioglu O (2003)

Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

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activities of peel pulp and seed fractions of common fruits as determined by

FRAP assay Nutrition Research 23 1719ndash1726

Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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superoxide in inflammation and immune regulation Journal of Physiology

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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curiosity cause or consequence Lancet 344 721ndash724

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Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

method a simple test tube assay for determination of rate constants for

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

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Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

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and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

treatment of metabolic syndrome Curr Opin Investig Drugs 5 283ndash289

Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

Hassan II Askar AA Gehan A EL-Shourbagy A (2004) Influence of

some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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hypobromite-mediated radical formation and its role in cell lysis Arch

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388-389

Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

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Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

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and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

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a causal role in multiple forms of insulin resistance Nature 440944ndash8

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Commun 106 37-43

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

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nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

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Kantartzis K Peter A Machicao F Machann J Wagner S

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Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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Khan MS Nema N Kharya MD and Khanam S (2009)

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

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Kotani K Peroni OD Minokoshi Y Boss O and Kahn BB (2004)

GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

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Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

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ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

Kowdley KV (2000) Ursodeoxycholic acid therapy in hepatobiliary

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Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

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Kresge N Simoni RD and Hill RL (2006) Forty years of superoxide

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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7 330-338

Kroumltz F Sohn HY and Gloe T (2002) Oxidase-dependent platelet

superoxide anion release incrj5eases platelet recruitment Blood 100 917-

924

Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

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Kumar G Sharmila Banu G Kannan V and Rajasekarapandian M

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damage in rats Indian J Exp Biol 43 351-355

Kumar V Rani A Dixit A K Pratap D and Bhatnagar D (2010) A

comparative assessment of total phenolic content ferric reducing-anti-

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Kumpulainen JT and Salonen JT (1999) Natural Antioxidants and

Anticarcinogens in Nutrition Health and Disease the Royal Society of

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Kuo YH and Li YC (2000) Four new compounds ficusal

ficusesquilignan A B and ficusolide diacetate from the heartwood of Ficus

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Kuriakose GC and Kurup GM (2008) Antioxidant activity of Aulosira

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59

Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

Desmodium gangeticum (L) root protects rat heart against ischemic

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Labhal A Settaf A Bennani N Cherrah Y Slaoui A and Hassar M

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Labhal A Settaf A Zalagh F Cherrah Y Hassar M and Slaoui A

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of the head of bacteriophage T4 Nature 227 680-685

Lagiou P Samoli E and Lagiou A (2004) Intake of specific flavonoid

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Lai LS Chan ST and Chao WW (2001) Studies on the antioxidative

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963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

and Newmana B (2008) Ficus spp (fig) Ethnobotany and potential as

anticancer and anti-inflammatory agents Journal of Ethnopharmacology

119 195ndash213

Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

Gioia S Marzio L Di Ilio C and Cuccurullo F (1992) Effects of high-

fat cholesterol-enriched diet on the antioxidant defence mechanisms in the

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Latha M and Pari L (2004) Effect of an aqueous extract of Scoparia dulcis

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steatohepatitis Hepatology 39(5) 1277-1285

Laurin J Lindor KD Crippin JS Gossard A Gores GJ Ludwig J

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treatment of non-alcohol-induced steatohepatitis a pilot study Hepatology

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

lipid-lowering and insulin-sensitizing actions in the rat Journal of

Ethnopharmacology 94 251ndash259

Leclercq I Field J Erriquez A Farrell GC (2007) Robertson G

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CYP4A in leptin-deficient obob mice Biochim Biophys Res Commun 268

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

of animal models Acta Gastroenterol Belg 7025ndash31

Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Lee KW Everts H Kappert HJ Yeom KH and Beynen AC (2003)

Dietary carvacrol lowers body weight gain but improves feed conversion in

female broiler chickens Journal of Applied Poultry Research 12 394ndash399

Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

extracts for antioxidant activity Life Sci 73 167-179

Leeuenberg C and Ji LL (1995) Glutathione depletion in rested and

exercised mice Biochemical consequence and adaption Arch Biochem

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

type 2 diabetes Advanced Drug Delivery Reviews 54 1199ndash1212

Leung KK and Leung PS (2008) Effects of hyperglycemia on

angiotensin receptor type 1 expression and insulin secretion in an INS-1E

pancreatic beta-cell line JOP 9 290ndash299

Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

Lichtenthaler R and Marx F (2005) Total oxidant scavenging capacities of

common European fruit and vegetable juices Journal of Agricultural and

Food Chemistry 53(1) 103minus110

Lieber CS (1997) Cytochrome P-4502E1 its physiological and

pathological role Physiol Rev 77 517ndash 44

Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

coactivation of SREBP Cell 120261ndash73

Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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SM (1994) Ursodeoxycholic acid in the treatment of primary biliary

cirrhosis Gastroenterology 106 1284ndash1290

Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

Angulo P (2004) Ursodeoxycholic for treatment of non-alcoholic steatohepatitis

results of a randomized trial Hepatology 39 770-8

Liochev SI and Fridovich I (1994) The role of O2 in the production of

HO in vitro and in vivo Free Radical Biology and Medicine 16 29ndash36

Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

transplant patients Nutr Rev 60 368-371

Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

biomarkers of inflammation and endothelial dysfunction J Nutr 135 562ndash

566

Louchami K Zhang Y Oguzhan B Delporte C Portois L and

Carpentier YA (2006) Rapid changes in liver lipid composition and

pancreatic islet K+ handling and secretory behaviour provoked by the

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Lowry OH Rosebrough NJ Farr AI and Randall RJ (1951) Protein

determination with the folinlsquos phenol reagent JBiolChem 193 265-275

Luck H (1974) In Methods in enzymatic analysisBer Acad N Y 885

Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

steatohepatitis Mayo clinic experiences with a hitherto unnamed disease

Mayo Clin Proc 55434-438

Lugasi A Dworschak E Blazovics A and Kery A (1998) Antioxidant

and free radical scavenging properties of squeezed juice from black radish

(Raphanus sativus I Varniger) root Phytother Res 12 502-506

Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

AA and Khalifa AA (2002) Inhibition of methylnitrosourea (MNU)

induced oxidative stress and carcinogenesis by orally administered bee honey

and Nigella grains in Sprague Dawely rats Journal of Experimental and

Clinical Cancer Research 21 (3) 341ndash346

Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

scavenging potential of Saussarea costua Acta Pharm 55 297-304

Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

cambogia extract on ethanol induced peroxidative damage in rats Indian J

Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

sativa oil against the liver damage induced by Shistosoma mansoni infection

in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

Malik EP Singh MB (1980) Plant Enzymology and Hittoenzymology

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

GK (2007) Phytochemical Studies of Strychnos potatorum LF A

Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

A Enrich C Fernandez-Checa JC and Garcia-Ruiz C (2006)

Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

Formosana J Sci Food Agric 88

Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

(2008) Molecular basis and mechanisms of progression of non-alcoholic

steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

Labaudiniere RF (1999) J Med Chem 42 3251e3264

Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

Rev 21 585e618

Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

Brief Scientific Literature Review Research Diets Inc 3000-2-09

Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

Mayes AP (1993) Structure and function of the lipid soluble vitamins In

Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

glutathione transferase activities in the human artery vein and heart J Mol

Cell Cardiol 22 935-938

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Michalak A (2006) Phenolic compounds and their antioxidant activity in

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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steatohepatitis Hepatology 37 909ndash16

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Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

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steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

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Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

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Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

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Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Rahman NN Khan M and Hasan R (1994) Bioactive components from

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Rajesh MG and Latha MS (2004) Preliminary evaluation of the

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

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Reddy AR Chiatanya KV and vivekanandan M (2004) Draught

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

Reid AE (2001) Nonalcoholic steatohepatitis Gasteroenterology 121

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Reitman S Frankel S (1957) Amer JClin Path 2856

Rennberg H (1987) Aspects of glutathione function and metabolism in

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York Plenum Press 279-292

Rice EW (1970) Triglycerides in serum In Roderick P MacDc aid CH

(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

Rice-Evans CA Miller NJ and Paganga G (1996) Structurendashantioxidant

activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Richter C (1987) Biophysical consequences of lipid peroxidation in

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Antioxidant properties of polyphenol-containing extract from soybean

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Nonalcoholic steatohepatitis association of insulin resistance and

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Wang X and Quinn P (1999) Vitamin E and its function in membranes

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Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

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PMID 15046985

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modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

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Physiology 128 379ndash391

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Preparation and Pharmacological evaluation of plant material England John

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Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

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reducing antioxidant power assay Food Chem 97 705-711

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World Health Organisation (2006) Obesity and overweight Fact sheet 311

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Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

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rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

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dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

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Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

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mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

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plasma of rats deficient in choline Biochem Cell Biol 68 552-558

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alcoholic fatty liver in mice Hepatology 42 568ndash577

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spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Med 20 693-702

Page 7: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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Cakir A Ahmet Yildirim MA Duru M E HArmandar M and Kazaz

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Cave M Deaciuc I Mendez C Song Z Joshi-Barve S and Barve S

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Cheikh Rouhou S Besbes S Hentati B Blecker C Deroanne C and

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Cheikh Rouhou S Hentati B Besbes S Blecker C Deroanne C and

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Chiang MY Chang JY Kuo CC Chang CY and Kuo YH (2005)

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Choudhury J and Sanyal AJ (2004) Insulin resistance and the

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Cioffi G Dal Piaz F De Caprariis P Sanego R Marzocco S Autore

G and De Tommasi N (2006) Antiproliferative triterpene saponins from

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Am J Physiol Gastrointest Liver Physiol 281 G865ndash869

Comalada MD CAmuesco S Sierra I Ballester J Xaus J Galvez and

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Daba MH and Abdel-Rahman MS (1998) Hepatoprotective activity of

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Dandona P Aljada A Chaudhuri A Mohanty P and Rajesh G (2004)

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Daniel RS Mathew BC Devi KS and Augusti KT (1998) Antioxidant

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Das S Vasisht S Das SN and Srivastava LM (2000) Correlation

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Das U (2002) A radical approach to cancer Med Sci Monit 8 RA79ndash92

Day CP James O (1998) Steatohepatitis a tale of two hits

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De Jong N Plat J and Mensink RP (2003) Metabolic effects of plant

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Deladino L Anbinder PS Navarro AS and Martino MN (2008)

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Delazar A Reid RG and Sarker SD (2004) GC-MS analysis of the

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of Natural compounds 40(1) 4-27

Denechaud PD Dentin R Girard J and Postic C (2008) Role of

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Deng J Wangyuan Cheng and Guangzhong Yang (2011) A novel

antioxidant activity index (AAU) for natural products using the DPPH assay

Food Chemistry 125 1430ndash1435

Dentin R Girard J and Postic C (2005) Carbohydrate responsive element

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(SREBP-1c) two key regulators of glucose metabolism and lipid synthesis in

liver Biochime 8781ndash6

Devasagayam TPA Kamat JP and Sreejayan N (2001) Antioxidant

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Di Carlo G Mascolo N and Izzo AA (1999) Flavonoids old and new

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Di Majo D Giammanco M La Guardia M Tripoli E Giammanco S

and Finotti E (2005) Flavonones in citrus fruit Structure-antioxidant

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Diehl AM (2003) Non-alcoholic steatohepatitis pathogenesis In Arroyo

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Dinnis TCP Maderia VM and Almeida LM (1994) Action of phenolic

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reesterification in triglycerides secretion and in FFA reesterification Am J

Physiol 274 E321ndashE327

Domenicali M Vendemiale G Serviddio G Grattagliano I Pertosa

AM Nardo B Principe A Viola A Trevisani F Altomare E

Bernardi M and Caraceni P (2005) Oxidative injury in rat liver exposed to

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689ndash697

Donnelly KL Smith CI Schwarzenberg SJ Jessurun J Boldt MD

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Doreswamy R and Sharma D (1995) Plant drugs for liver disorders

management Indian Drugs 32 139

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Doumas BT Watson WA (1971) Clin Chem Acta 31 87

Drager BJ (2002) Analysis of tropane and related alkaloids

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Duh PD Tu YY and Yen GC (1999) Antioxidant activity of aqueous

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Dunn WL (1974) Hand book of histopathological and histochemical

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Duvnjak M Lerotic I Barsic N Tomasic V Virovic Jukic L and

Velagic V (2007) Pathogenesis and management issues for non-alcoholic

fatty liver disease World J Gastroenterol 13 4539ndash4550

Eaton DL and Bammler TK (1999) Concise review of Glutathione-S-

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Eisenberg M Kessler RC Foster C Norlock FE Calkins DR and

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radical scavenging properties of lignans Organic and Bimolecular

Chemistry 21 3336ndash3347

Ekstedt M Franzeacuten LE Mathiesen UL Thorelius L Holmqvist M

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Ellmam GC (1959) Tissue sulfhydryl groups Archives of Biochemistry

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Emery MG Fisher JM and Chien JY (2003) CYP2E1 activity before

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

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Esterbauer H Schaur RJ and Zollner H (1991) Chemistry and

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Free Radical Biology amp Medicine 11 (1) 81ndash128

Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fan JG Zhu J and Li XJ (2005) Fatty liver and the metabolic syndrome

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

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Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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Ferannini E Natalie A and Bell P (1997)Insulin resistance and

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Flora SJ (2007) Role of free radicals and antioxidants in health and disease

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Foyer CH and Halliwell B (1976) The presence of glutathione activation

during plant stress Proceedings of the Royal Society of Edinburgh 102B

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Fraga C Leibovitz B and Tappel A (1987a) Halogenated compounds as

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Medicine 3 119-123

Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

15 381

Gaetani G Ferraris A and Rolfo M (1996) Predominant role of catalase

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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products typically consumed in Italy Italian Journal of Food Science 21(3)

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

Evaluation of hepatoprotective effect of Amalkadi Ghrita against CCl4

induced hepatic damage in rats J Ethanopharmacology 90 229-232

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Goris AH and Westerterp KR (2008) Physical activity fat intake and

body fat Physiol Behav 94 164ndash8

Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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and oxidative stress in rats Eur J Clin Invest 38 523-530

Gray (2008) Anatomy The Anatomical basis of clinical practice Chap 68

Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

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Grill V and Bjoumlrklund A (2009) Impact of metabolic abnormalities for

beta cell function clinical significance and underlying mechanisms Mol

Cell Endocrinol 297 86ndash92

Grusak MA (2002) Phytochemicals in plants genomics-assisted plant

improvement for nutritional and health benefits Curr Opin Biotechnol 13

508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

Guumllccedilin I Mshvildadze VA Gepdiremen A and Elias R (2006) The

antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

Research 20 130ndash134

Gulcin Buyukokuroglu ME Oktay M and Kufrevioglu O (2003)

Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

Pallsiana (Lamb) Holmboe J Ethanopharm 86 51-58

Guo C Yang J Wei J Li Y Xu J and Jiang Y (2003) Antioxidant

activities of peel pulp and seed fractions of common fruits as determined by

FRAP assay Nutrition Research 23 1719ndash1726

Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

Guzik TJ Korbut R and Adamek-Guzik T (2003) Nitric oxide and

superoxide in inflammation and immune regulation Journal of Physiology

and Pharmacology 54 (4) 469-487

Gyamfi MA Yonamine M and Aniya Y (1999) Free-radical scavenging

action of medicinal herbs from Ghana Thonningia sanguine on

experimentally induced liver injuries General Pharmacol 32 661-667

Habig WH Pabst MJ and Jacob WB (1974) Glutathione-S-transferase

the first enzymatic step in mercapturic acid formation JBiolChem 249

7130-7139

Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

Haddad Y Vallerand D Brault A and Haddad PS (2009) Antioxidant

and hepatoprotective effects of silibinin in a rat model of nonalcoholic

steatohepatitis eCAM doi101093ecamnep 164

Halliwell B (1977) Generation of hydrogen peroxide superoxide and

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peroxidase Biochem J 163 441-448

Halliwell B (1991) Reactive oxygen species in living systems source

biochemistry and role in human disease American Journal of Medicine

91(suppl 3C) 14Sndash22S

Halliwell B (1993) The role of oxygen radicals in human disease with

particular reference to the vascular system Haemostasis 23 Suppl 1 118-

126

Halliwell B (1994) Free radicals antioxidants and human disease

curiosity cause or consequence Lancet 344 721ndash724

Halliwell B (1996) Antioxidants in human health and disease Annual

Review of Nutrition 16 33-50

Halliwell B (1999) Antioxidant defence mechanisms from the beginning

to the end (of the beginning) Free Radical Research 31 261-272

Halliwell B (2000) Why and how should we measure oxidative DNA

damage in nutritional studies How far have we come Am J Clin Nutr 72

1082-1087

Halliwell B (2001) Role of free radicals in the neurodegenerative diseases

therapeutic implications for antioxidant treatment Drugs Aging 18 685-

716

Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

damage a biomarker Free Radic Biol Med 32 968-974

Halliwell B (2006) Reactive species and antioxidants Redox biology is a

fundamental theme of aerobic life Plant Physiol 141 312-322

Halliwell B and Gutteridge JM (1995) The definition and measurement of

antioxidants in biological systems Free Radical Biol Med 18 125ndash126

Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

characterization of antioxidant Food Chem Toxicol 33 601-617

Halliwell B Gutteridge JM and Cross CE (1992) Free radicals

antioxidants and human disease where are we now J Lab Clin Med 119

598-620

Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

method a simple test tube assay for determination of rate constants for

reactions of hydroxyl radicals Analytical Biochemistry 165 215ndash219

Hamed and Manal A (2011) Beneficial effect of Ficus religiosa Linn on

high-fat-diet-induced hypercholesterolemia in rats Food Chemistry 129

162ndash170

Handa SS Sharma A and Charaborti KK (1986) Natural products and

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Amazon Journal of Ethnopharmacology 98 251ndash257

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treatment of metabolic syndrome Curr Opin Investig Drugs 5 283ndash289

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some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

Animal Science 45 663ndash670

Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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changes in microheological properties of the red cell membrane 76 1015-

1022

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Methods in Carbohydrate chemistry ML Academic Press New York 1

388-389

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Linn root extract against CCl4 and paracetamol induced hepatic oxidative

stress Indian Journal of Experimental Biology 47 660-667

Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

in rats African Journal of Biochemistry 2(6) 141-144

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I Smid E J Gorris L G and Von Wright A (1998) J Agric Food

Chem46 3590

Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

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Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

selectivity Cancer Chemother Pharmacol 53 209ndash19

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and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

metabolism J Cell Physiol 210 7ndash15

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106 1219-1228

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erythrocyte superoxide dismutase with hydrogen peroxide

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in vivo British Medical Bulletin 49 494ndash505

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determination of free fatty acids in plasma J Lipid Res 22 377-381

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Lipidol 10 143ndash50

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Nigella sativa and derived thymoquinone inhibit eicosanoid generation in

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a causal role in multiple forms of insulin resistance Nature 440944ndash8

httpclinicaltrialsgovct2showNCT00065676intrfrac1422quercetin

22amprankfrac145 (accessed 170609)

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extract suppresses both reactive oxygen species and nitric oxide and prevents

lipid oxidation in vitro Phytomedicine 12 588ndash597

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capacity assays Journal of Agricultural and Food Chemistry 53(6)

1841minus1856

Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

MJ and Weinrauch Y (2008) Reactive nitrogen species contribute to

innate host defense against Camoylobacter jjuni Infection and Immunity

76(3) 986-93

Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

Food Chem 114 466ndash471

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15 755-766

Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

Hepatoprotective activity of ethanolic and aqueous extract of Amorphallus

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WB (ed) Enzymatic Basis of Detoxification Academic press New York

63-94

James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

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results in rodent models of atherosclerosis are not interchangeable the

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stability of ethanolic extracts of Holy basil and Galangal Food Chem 92

193ndash202

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and spinal cord injury suggestions for pharmacological and nutritional

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Kiyoshi Mizuguchi (2009) Suppression of hepatic fat accumulation by

highly purified eicosapentaenoic acid prevents the progression of D-

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proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

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properties of tocopherols and tocotrienols Lipids 31 671-701

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Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

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Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

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Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

Malik EP Singh MB (1980) Plant Enzymology and Hittoenzymology

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

GK (2007) Phytochemical Studies of Strychnos potatorum LF A

Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

A Enrich C Fernandez-Checa JC and Garcia-Ruiz C (2006)

Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

(2008) Molecular basis and mechanisms of progression of non-alcoholic

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

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morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

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genotypes under stress of different concentrations of sucrose and sorbito

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patients Nutr Rev 58 278-281

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biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

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and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

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radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

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syndrome) and obesity in Asian Indians Evidence and implications

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Rahman NN Khan M and Hasan R (1994) Bioactive components from

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Richter C (1987) Biophysical consequences of lipid peroxidation in

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

(5) G1135ndashG1139

Roe J H and Keuther C A (1943) The determination of ascorbic acid in

whole blood and urine through 2 4-dinitro phenyl hydrazine derivative of

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Rohrdanz E Schmuck G Ohler S and Kahl R (2001) The influence of

oxidative stress on catalase and MnSOD gene transcription in astrocytes

Brain Res 900 128-136

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dcrease in lipid peroxidation after vitamin E dietary supplementation in

guinea pigs Free Radic Biol Med 21 907-15

Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

MG (2010) Int J Obes (Lond) 34 190ndash194

Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

fermented with Saccharomyces cerevisiae Eur J Lipid Sci Technol 106

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with signs and symptoms of liver disease In clinical practice of

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

Roy S Sehgal R Pahdy BM and Kumar VL (2005) Antioxidant and

protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

(2008) Micellarisation of carotenoids from raw and cooked vegetables

Plant Foods for Human Nutrition 63(3) 127minus133

Sadasivam S Manickam A (1997) Biochemical methods Second edition

Newage international Pvt Ltd

Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

(2004) Up regulation of osteopontin expression is involved in the

development of non-alcoholic steatohepatitis in a dietary murine model Am

J Physiol Gastrointest Liver Physiol 287 G264-G273

Sahreen S Rashid Khan M and Ali Khan R (2010) Evaluation of

antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

RK (2002) Antiulcerogenic activity of methanolic extract of Emblica

Officinalis Journal of Ethanopharmacology 82 1-9

Sallie R Tredgr JM and William (1999) Drugs and the liver Biopharm

Drug Dispos 12 251-259

Salom S M Gray J A Alford A R Mulesky M Fettig C J and

Woods S A (1996) J Entomol Sci 31 453

Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

AJ and Shulman GI (2004) Mechanism of hepatic insulin resistance in

non-alcoholic fatty liver disease J Biol Chem 279 32345-32353

Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

Sarabu R and Tilley J (2005) Annu Rep Med Chem 40 167e181

Elsevier Academic Press

Sasaki YF Kawaguchi S KamayaA OhshitaM Kabasawa K and

Iwama K (2002) The comet assay with 8 mouse organs Results with 39

currently used food additives Mutation ResearchGenetic Toxicology and

Environmental Mutagenesis 519 103ndash109

Satheesh AM and Pari L (2004) Antioxidant effect of Boerhavia diffusa

L in tissues of alloxan induced diabetic rats Indian J Exp Biol 42 989-

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Satyavati GV (1982) Some traditional medical systems and practise of

global importance Indian J Med Res 76 1

Sauberlich HE (1999) Laboratory tests for the assessment of nutritional

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Ed CRC press Boca RatonFL

Scandalios JG (1987) The antioxidant enzyme genes CAT and SOD of

maize regulation functional significance and molecular biology

Isoenzymes Curr Top Biol Med Res 14 19-44

Schaalan M El-Abhar HS Barakat M and El-Denshary ES (2008)

Westernized-likediet-fed rats effect on glucose homeostasis lipid profile

and adipocyte hormones and their modulation by rosiglitazone and

glimepiride J Diabetes Complications 23199ndash208

Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

resistance Proc Nutr Soc 66 33ndash41

Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

Lab Clin Med 118 7-16

Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

Physiol Pharamacol 39 177

Sen CK (2003) The general case for redox control of wound repair

Wound Repair and Regeneration 11 431-438

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Cakir A Ahmet Yildirim MA Duru M E HArmandar M and Kazaz

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Ceriello A (2003) New insights on oxidative stress and diabetic

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Ceylan-Isik AF Fliethman RM Wold LE and Ren J (2008) Herbal

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Charlton M Sreekumar R Rasmussen D Lindor K and Nair KS

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Chatterjee TK (2000) Medicinal plants with hepatoprotective properties in

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Chaudary SA Tayyab M and Ditta A (1996) Serum Lipid Profile in

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Cheikh Rouhou S Besbes S Hentati B Blecker C Deroanne C and

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Cheikh Rouhou S Hentati B Besbes S Blecker C Deroanne C and

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Food Chemistry 125 1430ndash1435

Dentin R Girard J and Postic C (2005) Carbohydrate responsive element

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Di Majo D Giammanco M La Guardia M Tripoli E Giammanco S

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

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Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

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in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

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Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

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508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

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antioxidant activity of a triterpenoid glycoside isolated from the berries of

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disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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superoxide in inflammation and immune regulation Journal of Physiology

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

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Handa SS Sharma A and Charaborti KK (1986) Natural products and

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

JG Magee WP Dalvie DK Soliman VF Martin WH Mularski CJ

and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

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Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

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some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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Hedge JE and Hofreiter BT (1962) Detremination of reducing sugars

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388-389

Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

in rats African Journal of Biochemistry 2(6) 141-144

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Chem46 3590

Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

selectivity Cancer Chemother Pharmacol 53 209ndash19

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a causal role in multiple forms of insulin resistance Nature 440944ndash8

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

MJ and Weinrauch Y (2008) Reactive nitrogen species contribute to

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

Jayasooriya A P Sakono M and Yukizaki C (2000) Effects of

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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193ndash202

Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

diet Biochimica et Biophysica Acta 1791 281ndash288

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spectrophotometric assay of superoxide dismutase Indian J

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

(2000) Radio-protective properties of Asparagus racemosus in vitro in rat

liver mitochondria JEthanopharmacol 71 425-435

Kamboj VP (2000) Herbal medicine Curr Med 78 35-39

Kantartzis K Peter A Machicao F Machann J Wagner S

Koumlnigsrainer I Koumlnigsrainer A Schick F Fritsche A Haumlring HU

and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

59ndash75) London UK Taylor and Francis Press

Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

rats Phytotherapy Research 13(2) 95-101

Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

55 2824ndash8

Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

Experimental 35 655-657

Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

K (2005) Potential of sourdough for healthier cereal products Trends Food

Science and Technology 16 104ndash112

Katz D Mazor D Dvilansky A and Meyerstein N (1996) Effect of

radiation on red cell membrane and intracellular oxidative defense systems

Free Radical Research 24 199ndash204

Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

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teerpenoid diversity in the constitutive and induced defence of coniters

against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

Ipomoea mauritiana 1 22-30

Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

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scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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system Ann Clin Lab Sci 30 145-158

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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supplementation retards early progression of arteriosclerosis in heart

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Michalak A (2006) Phenolic compounds and their antioxidant activity in

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

formulation in galactosamine induced hepatopathy in rats Indian J Physiol

Pharmacol 44 82-86

Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

Mucuna pruriens Linn And formation containing Mpruriens by HPTLC

method Chem Pharma Bull 56(3) 357

Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

International Journal of Biotechnology amp Biochemistry 303-323

Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

Moncada A Palmaer RMJ and Higgs EA (1991) Nitric oxide

physiology pathophysiology and pharmacology Pharmacol Rev 43 109-

1421

Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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Morris GM Goodsell DS Halliday RS Huey R Hart WE Belew

RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

algorithm and an empirical binding free energy function J Comput Chem

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Morrissey JP and Osbourn AE (1999) Fungal resistance to plant

antibiotics as a mechanism of pathogenesis Microbiological and Molecular

Biological Reviews 63 708-724

Moss DW and Butterorth PJ (1974) Enzymology and Medicine London

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Mozaffari FS Ghorbani M Babai A and Farzami Sepehr M (2000)

The effect of water stress on the seed oil of Nigella sativa L J Essent Oil

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Mursu J Voutilainen S Nurmi T Tuomainen TP Kurl S and Salonen

JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

Nadakarni KM (1976) Corcus sativus Nigella sativa In Nadkarni KM

(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

411

Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Lipids 99 11-19

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carotenoids are more bioaccessible from fruits than dark green vegetables

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acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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convenient substrate for determination and study of L-and D-glutamyl trans

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(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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diabetes Science 306457ndash61

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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(2009b) The beneficial effects of morroniside on the inflammatory response

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289e298

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

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with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

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Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Daniel RS Mathew BC Devi KS and Augusti KT (1998) Antioxidant

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Donnelly KL Smith CI Schwarzenberg SJ Jessurun J Boldt MD

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Eisenberg M Kessler RC Foster C Norlock FE Calkins DR and

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Ekstedt M Franzeacuten LE Mathiesen UL Thorelius L Holmqvist M

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Ellmam GC (1959) Tissue sulfhydryl groups Archives of Biochemistry

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

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Esterbauer H Schaur RJ and Zollner H (1991) Chemistry and

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Free Radical Biology amp Medicine 11 (1) 81ndash128

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Fan JG Zhu J and Li XJ (2005) Fatty liver and the metabolic syndrome

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

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Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

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Ferannini E Natalie A and Bell P (1997)Insulin resistance and

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during plant stress Proceedings of the Royal Society of Edinburgh 102B

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inducers of lipid peroxidation in tissue slices Free Radical Biology and

Medicine 3 119-123

Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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body fat Physiol Behav 94 164ndash8

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

liver chemistry tests Gasteroenteerology 123 1367-1384

Grill V and Bjoumlrklund A (2009) Impact of metabolic abnormalities for

beta cell function clinical significance and underlying mechanisms Mol

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improvement for nutritional and health benefits Curr Opin Biotechnol 13

508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

Guumllccedilin I Mshvildadze VA Gepdiremen A and Elias R (2006) The

antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

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Gulcin Buyukokuroglu ME Oktay M and Kufrevioglu O (2003)

Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

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activities of peel pulp and seed fractions of common fruits as determined by

FRAP assay Nutrition Research 23 1719ndash1726

Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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superoxide in inflammation and immune regulation Journal of Physiology

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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Halliwell B (1993) The role of oxygen radicals in human disease with

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Halliwell B (1994) Free radicals antioxidants and human disease

curiosity cause or consequence Lancet 344 721ndash724

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Halliwell B (2001) Role of free radicals in the neurodegenerative diseases

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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Halliwell B (2006) Reactive species and antioxidants Redox biology is a

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Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

characterization of antioxidant Food Chem Toxicol 33 601-617

Halliwell B Gutteridge JM and Cross CE (1992) Free radicals

antioxidants and human disease where are we now J Lab Clin Med 119

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

method a simple test tube assay for determination of rate constants for

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plants as lives protecting drugs Fitoterpia 57 307-45

Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

Harada N Oda Z Hara Y Fujinami K Okawa M Ohbuchi K

Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harbrone JBC (1973) Phytochemical methods Chapman and Hall

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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mRNA in fulminant hepatic failure Lancet 344 27ndash29

Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

JG Magee WP Dalvie DK Soliman VF Martin WH Mularski CJ

and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

treatment of metabolic syndrome Curr Opin Investig Drugs 5 283ndash289

Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

Hassan II Askar AA Gehan A EL-Shourbagy A (2004) Influence of

some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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Hedge JE and Hofreiter BT (1962) Detremination of reducing sugars

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388-389

Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

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Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

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Hillwell B (1994) Free radicals antioxidants and human disease Curiosity

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and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

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in vivo British Medical Bulletin 49 494ndash505

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a causal role in multiple forms of insulin resistance Nature 440944ndash8

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22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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Kakkar P Das B and Vishwanathan P N (1984) A modified

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

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Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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Khan MS Nema N Kharya MD and Khanam S (2009)

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

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Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

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Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

and Dosso M (2004) Traditional medicine in North Cocircte-DlsquoIvoire

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Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

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Korchak HM (1962) Regulation of hepatic lipogenesis Tufts Folia Med

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

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and Food Chemistry 53 1408ndash1416

Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

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Gastroenterology 37 177ndash182

Kotani K Peroni OD Minokoshi Y Boss O and Kahn BB (2004)

GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

Koteish A and Diehl AM (2002) Animal models of steatohepatitis Best

Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not

ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

Kowdley KV (2000) Ursodeoxycholic acid therapy in hepatobiliary

disease Am J Med 108 481ndash486

Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

resistance in high-fat-fed rats Diabetes 40 1397 ndash 1403

Kresge N Simoni RD and Hill RL (2006) Forty years of superoxide

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17-19

Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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7 330-338

Kroumltz F Sohn HY and Gloe T (2002) Oxidase-dependent platelet

superoxide anion release incrj5eases platelet recruitment Blood 100 917-

924

Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

mice inhibits neither the CDP-choline pathway for phosphatidylcholine

synthesis in hepatocytes nor apolipoprotein B secretion J Biol Chem 279

23916-23924

Kumar G Sharmila Banu G Kannan V and Rajasekarapandian M

(2005) Antihepatotoxic effect of β-carotene on paracetamol induced hepatic

damage in rats Indian J Exp Biol 43 351-355

Kumar V Rani A Dixit A K Pratap D and Bhatnagar D (2010) A

comparative assessment of total phenolic content ferric reducing-anti-

oxidative power free radical-scavenging activity vitamin C and isoflavones

content in soybean with varying seed coat colour Food Research

International 43 323minus328

Kumpulainen JT and Salonen JT (1999) Natural Antioxidants and

Anticarcinogens in Nutrition Health and Disease the Royal Society of

Chemistry UK 178-187

Kuo YH and Li YC (2000) Four new compounds ficusal

ficusesquilignan A B and ficusolide diacetate from the heartwood of Ficus

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Kuriakose GC and Kurup GM (2008) Antioxidant activity of Aulosira

fertilisima on CCl4 induced hepatotoxicity in rats Indian J Exp Bio 46 52-

59

Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

Desmodium gangeticum (L) root protects rat heart against ischemic

reperfusion injury induced oxidative stress Indian J Exp Biol 47 129ndash35

Labhal A Settaf A Bennani N Cherrah Y Slaoui A and Hassar M

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le rat des sables Caduceacutee 27 26ndash28

Labhal A Settaf A Zalagh F Cherrah Y Hassar M and Slaoui A

(1999) Proprieacuteteacutes anti-diabeacutetiques des graines de Nigella sativa chez le

Meriones shawi obegravese et diabeacutetique Espeacuterance Meacutedicale 47 72ndash74

Laemmli U K (1970) Cleavage of structural proteins during the assembly

of the head of bacteriophage T4 Nature 227 680-685

Lagiou P Samoli E and Lagiou A (2004) Intake of specific flavonoid

classes and coronary heart disease-a case-control study in Greece Eur J

Clin Nutr 58 (12) 1643ndash1648

Lai LS Chan ST and Chao WW (2001) Studies on the antioxidative

activities of mesona procumbers Hemsleaf gum J Agric Food Chem 19

963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

and Newmana B (2008) Ficus spp (fig) Ethnobotany and potential as

anticancer and anti-inflammatory agents Journal of Ethnopharmacology

119 195ndash213

Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

Gioia S Marzio L Di Ilio C and Cuccurullo F (1992) Effects of high-

fat cholesterol-enriched diet on the antioxidant defence mechanisms in the

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Larson RA (1988) The antioxidants of higher plants Phytochemistry 27

969-78

Latha M and Pari L (2004) Effect of an aqueous extract of Scoparia dulcis

on blood glucose plasma insulin and some polyol pathway enzymes in

experimental rat diabetes Brazilian J Med Biol Res 37 577-586

Laurent A Nicco C and Tran Van Nhieu J (2004) Pivotal role of

superoxide anion and beneficial effect of antioxidant molecules in murine

steatohepatitis Hepatology 39(5) 1277-1285

Laurin J Lindor KD Crippin JS Gossard A Gores GJ Ludwig J

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treatment of non-alcohol-induced steatohepatitis a pilot study Hepatology

23 1464ndash1467

Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

lipid-lowering and insulin-sensitizing actions in the rat Journal of

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Leclercq I Field J Erriquez A Farrell GC (2007) Robertson G

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CYP4A in leptin-deficient obob mice Biochim Biophys Res Commun 268

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

of animal models Acta Gastroenterol Belg 7025ndash31

Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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1896

Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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hepatic stellate cells by TGF alpha and collagen type I is mediated by

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Lee KW Everts H Kappert HJ Yeom KH and Beynen AC (2003)

Dietary carvacrol lowers body weight gain but improves feed conversion in

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extracts for antioxidant activity Life Sci 73 167-179

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

type 2 diabetes Advanced Drug Delivery Reviews 54 1199ndash1212

Leung KK and Leung PS (2008) Effects of hyperglycemia on

angiotensin receptor type 1 expression and insulin secretion in an INS-1E

pancreatic beta-cell line JOP 9 290ndash299

Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Food Chemistry 53(1) 103minus110

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pathological role Physiol Rev 77 517ndash 44

Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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Liochev SI and Fridovich I (1994) The role of O2 in the production of

HO in vitro and in vivo Free Radical Biology and Medicine 16 29ndash36

Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

transplant patients Nutr Rev 60 368-371

Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

Carpentier YA (2006) Rapid changes in liver lipid composition and

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determination with the folinlsquos phenol reagent JBiolChem 193 265-275

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Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

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Mayo Clin Proc 55434-438

Lugasi A Dworschak E Blazovics A and Kery A (1998) Antioxidant

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

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Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

sativa oil against the liver damage induced by Shistosoma mansoni infection

in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

Formosana J Sci Food Agric 88

Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

(2008) Molecular basis and mechanisms of progression of non-alcoholic

steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

Labaudiniere RF (1999) J Med Chem 42 3251e3264

Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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risk factor study Br J Nutr 100 (4) 890ndash895

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

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Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

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Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

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Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

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Molecular Biology 49 249-279

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Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

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Rheediinosides A and B two antiproliferative and antioxidant triterpene

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(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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convenient substrate for determination and study of L-and D-glutamyl trans

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Postharvest Biochemistry of Plant Food-Materials in Tropics Japan

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

Sci 5 445-459

Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

Ethanopharmacology 91 99-104

Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

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Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

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Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

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PMID 15046985

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Preparation and Pharmacological evaluation of plant material England John

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Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

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World Health Organisation (2006) Obesity and overweight Fact sheet 311

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Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

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Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

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Dentin R Girard J and Postic C (2005) Carbohydrate responsive element

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Di Majo D Giammanco M La Guardia M Tripoli E Giammanco S

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Diehl AM (2003) Non-alcoholic steatohepatitis pathogenesis In Arroyo

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Donnelly KL Smith CI Schwarzenberg SJ Jessurun J Boldt MD

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Eisenberg M Kessler RC Foster C Norlock FE Calkins DR and

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Ekstedt M Franzeacuten LE Mathiesen UL Thorelius L Holmqvist M

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1313ndash9

El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Emery MG Fisher JM and Chien JY (2003) CYP2E1 activity before

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

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Esterbauer H Schaur RJ and Zollner H (1991) Chemistry and

biochemistry of 4-hydroxynonenal malonaldehyde and related aldehydes

Free Radical Biology amp Medicine 11 (1) 81ndash128

Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

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in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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Flora SJ (2007) Role of free radicals and antioxidants in health and disease

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Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

15 381

Gaetani G Ferraris A and Rolfo M (1996) Predominant role of catalase

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Ganapathy S (2004) Emerging strategy in the study of natural products

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Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Gray (2008) Anatomy The Anatomical basis of clinical practice Chap 68

Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

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508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

Guumllccedilin I Mshvildadze VA Gepdiremen A and Elias R (2006) The

antioxidant activity of a triterpenoid glycoside isolated from the berries of

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Gupta R and Misra A (2007) Type 2 diabetes in India regional

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Gurumoorthy V Hindu Jan-23rd 2011

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action of medicinal herbs from Ghana Thonningia sanguine on

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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Halliwell B (1993) The role of oxygen radicals in human disease with

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Halliwell B (1994) Free radicals antioxidants and human disease

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Halliwell B (1996) Antioxidants in human health and disease Annual

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

characterization of antioxidant Food Chem Toxicol 33 601-617

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antioxidants and human disease where are we now J Lab Clin Med 119

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

method a simple test tube assay for determination of rate constants for

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Hamed and Manal A (2011) Beneficial effect of Ficus religiosa Linn on

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Handa SS Sharma A and Charaborti KK (1986) Natural products and

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

Harada N Oda Z Hara Y Fujinami K Okawa M Ohbuchi K

Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harbrone JBC (1973) Phytochemical methods Chapman and Hall

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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mRNA in fulminant hepatic failure Lancet 344 27ndash29

Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

JG Magee WP Dalvie DK Soliman VF Martin WH Mularski CJ

and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

treatment of metabolic syndrome Curr Opin Investig Drugs 5 283ndash289

Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

Hassan II Askar AA Gehan A EL-Shourbagy A (2004) Influence of

some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

Hausner EA Schlingmann KL Chen HW Gillies PJ Kieras CJ

Ross PE and Van Pelt CS (1995) Hepatic and adrenal changes in rabbits

associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

Animal Science 45 663ndash670

Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

Haynes P Liangpunsakul S and Chalasani N (2004) Nonalcoholic fatty

liver disease in individuals with severe obesity Clin Liver dis 8 535-547

Hebbel RP Leung A and Mohandas N (1990) Oxidation-induced

changes in microheological properties of the red cell membrane 76 1015-

1022

Hedge JE and Hofreiter BT (1962) Detremination of reducing sugars

Methods in Carbohydrate chemistry ML Academic Press New York 1

388-389

Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

Linn root extract against CCl4 and paracetamol induced hepatic oxidative

stress Indian Journal of Experimental Biology 47 660-667

Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

in rats African Journal of Biochemistry 2(6) 141-144

Helader L M Alakomi H-L Latva-Kala K Mattila- Sandholm T Pol

I Smid E J Gorris L G and Von Wright A (1998) J Agric Food

Chem46 3590

Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

selectivity Cancer Chemother Pharmacol 53 209ndash19

Hillwell B (1994) Free radicals antioxidants and human disease Curiosity

cause or constipation Lancet 344 721-724

Hirabara SM Silveira LR Abdulkader F Carvalho CR Procopio J

and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

metabolism J Cell Physiol 210 7ndash15

Ho Y Magnenat J Gargano M and Cao J (1998) Env Health Perspect

106 1219-1228

Hodgson EK and Fridovich I (1975) The interaction of bovine

erythrocyte superoxide dismutase with hydrogen peroxide

chemiluminescence and peroxidation Biochemistry 14 5299ndash5303

Holley AE and Cheeseman KH (1993) Measuring free radical reactions

in vivo British Medical Bulletin 49 494ndash505

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determination of free fatty acids in plasma J Lipid Res 22 377-381

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proteins activators of cholesterol and fatty acid biosynthesis Curr Opin

Lipidol 10 143ndash50

Houghton P J Zarka R Heras B and Hoult JRS (1995) Fixed oil of

Nigella sativa and derived thymoquinone inhibit eicosanoid generation in

leukocytes and membrane lipid peroxidation Planta Med 61 33-36

Houstis N Rosen ED Lander ES (2006) Reactive oxygen species have

a causal role in multiple forms of insulin resistance Nature 440944ndash8

httpclinicaltrialsgovct2showNCT00065676intrfrac1422quercetin

22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

extract suppresses both reactive oxygen species and nitric oxide and prevents

lipid oxidation in vitro Phytomedicine 12 588ndash597

Huang D Ou B and Prior RL (2005) The chemistry behind antioxidant

capacity assays Journal of Agricultural and Food Chemistry 53(6)

1841minus1856

Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

scientific review Journal of American Medical Association 287 360ndash372

Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

MJ and Weinrauch Y (2008) Reactive nitrogen species contribute to

innate host defense against Camoylobacter jjuni Infection and Immunity

76(3) 986-93

Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

Food Chem 114 466ndash471

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15 755-766

Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

Hepatoprotective activity of ethanolic and aqueous extract of Amorphallus

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6(4) 423-428

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WB (ed) Enzymatic Basis of Detoxification Academic press New York

63-94

James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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Momordica charantia powder on serum glucose levels and various lipid

parameters in rats fed with cholesterol-free and cholesterolenriched diets

Journal of Ethnopharmacology 72(1-2)331-336

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cancers of the alimentary tract Mutation Research 551(1ndash2) 9minus28

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

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Alonso-Villaverde C Aragones G Claria J and Camps J (2007) The

results in rodent models of atherosclerosis are not interchangeable the

influence of diet and strain Atherosclerosis 195 e85ndashe92

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stability of ethanolic extracts of Holy basil and Galangal Food Chem 92

193ndash202

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and spinal cord injury suggestions for pharmacological and nutritional

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Kiyoshi Mizuguchi (2009) Suppression of hepatic fat accumulation by

highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

diet Biochimica et Biophysica Acta 1791 281ndash288

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proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

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properties of tocopherols and tocotrienols Lipids 31 671-701

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Kantartzis K Peter A Machicao F Machann J Wagner S

Koumlnigsrainer I Koumlnigsrainer A Schick F Fritsche A Haumlring HU

and Stefan N (2009) Diabetes 58 2616ndash2623

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In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

59ndash75) London UK Taylor and Francis Press

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Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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55 2824ndash8

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Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Free Radical Research 24 199ndash204

Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

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and profound elevation of serum alanine aminotransferase in healthy

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Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

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(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

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Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

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963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

A Enrich C Fernandez-Checa JC and Garcia-Ruiz C (2006)

Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

Formosana J Sci Food Agric 88

Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

Labaudiniere RF (1999) J Med Chem 42 3251e3264

Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

Rev 21 585e618

Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

Brief Scientific Literature Review Research Diets Inc 3000-2-09

Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

Mayes AP (1993) Structure and function of the lipid soluble vitamins In

Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

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Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

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syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

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syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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Pharmaceutical Bulletin 36 1264ndash1269

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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glucose amine Japanese Journal of Nutrition 44307-315

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antioxidant vitamins and trace elements supplemented diets on activities of

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

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abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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decolorisation assay Free Radical Biol Med 26 1231-1237

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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(5) G1135ndashG1139

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

fermented with Saccharomyces cerevisiae Eur J Lipid Sci Technol 106

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

Roy S Sehgal R Pahdy BM and Kumar VL (2005) Antioxidant and

protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

(2008) Micellarisation of carotenoids from raw and cooked vegetables

Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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development of non-alcoholic steatohepatitis in a dietary murine model Am

J Physiol Gastrointest Liver Physiol 287 G264-G273

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Drug Dispos 12 251-259

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

AJ and Shulman GI (2004) Mechanism of hepatic insulin resistance in

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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Sasaki YF Kawaguchi S KamayaA OhshitaM Kabasawa K and

Iwama K (2002) The comet assay with 8 mouse organs Results with 39

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Satheesh AM and Pari L (2004) Antioxidant effect of Boerhavia diffusa

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Satyavati GV (1982) Some traditional medical systems and practise of

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Sauberlich HE (1999) Laboratory tests for the assessment of nutritional

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Ed CRC press Boca RatonFL

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Westernized-likediet-fed rats effect on glucose homeostasis lipid profile

and adipocyte hormones and their modulation by rosiglitazone and

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Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

resistance Proc Nutr Soc 66 33ndash41

Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Seth and Bhawana Sharma (2004) Medicinal plants in India Commentary

Indian J Med Res 120 9-11

Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

muscle) Therapie 46 351ndash354

Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

antioxidant studies of Ficus Racemosa Linnroot 13 (4) 70-74

Sharma P and Dubey RSH (2005) Drought induces stress and enhances

the activities of antioxidant enzymes in growing rice seedlings Plant Growth

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Shenoy KA Somayaji SN and Bairy KL (2001) Hepatoprotective

effects of Ginkgo biloba against CCl4 induced hepatic injury in rats Ind J

Pharamacol 33 260-266

Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

Y and Yoshimura K (2002) ―Regulation and function of ascorbate

peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

Shimada K Fujikawa K Yahara K and Nakamura T (1992)

Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

SREBP family FEBS J 276616ndash621

Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

Sies H (1997) Oxidative stress oxidants and antioxidants Exp Physiol

82 291-295

Sies H and Cadenas E (1985) Oxidative stress damage to intact cells and

organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

hydroxynonenal by JNKc-Jun overactivation Am J Physiol Gastrointest

Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

(2010) Antioxidant Properties of Ficus Species ndash A Review International

Journal of PharmTech Research CODEN (USA) IJPRIF ISSN 0974-

4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

Sivarajan VV and Balachandran I (1994) Ayurvedic Drugs and their

Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

Smid E J De Witte Y and Gorris L G M (1995) Postharvest Biol

Technol 6 303

Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

266

Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

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Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Donnelly KL Smith CI Schwarzenberg SJ Jessurun J Boldt MD

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Eaton DL and Bammler TK (1999) Concise review of Glutathione-S-

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Eisenberg M Kessler RC Foster C Norlock FE Calkins DR and

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radical scavenging properties of lignans Organic and Bimolecular

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Ekstedt M Franzeacuten LE Mathiesen UL Thorelius L Holmqvist M

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El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Ellmam GC (1959) Tissue sulfhydryl groups Archives of Biochemistry

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Emery MG Fisher JM and Chien JY (2003) CYP2E1 activity before

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

expression of hepatic CYP2E1 and CYP4A in obese diabetic obob mice

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Esterbauer H Schaur RJ and Zollner H (1991) Chemistry and

biochemistry of 4-hydroxynonenal malonaldehyde and related aldehydes

Free Radical Biology amp Medicine 11 (1) 81ndash128

Evans P and Halliwell B (1999) Free radicals and hearing Cause

consequence and criteria Ann N Y Acad Sci 884 19-40

Fan JG Zhu J and Li XJ (2005) Fatty liver and the metabolic syndrome

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

lysosomal pathway Hepatology 40 185ndash194

Ferannini E Natalie A and Bell P (1997)Insulin resistance and

hypersecretion in obesity J Clin Invest 100 1166

Flora SJ (2007) Role of free radicals and antioxidants in health and disease

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Foyer CH and Halliwell B (1976) The presence of glutathione activation

during plant stress Proceedings of the Royal Society of Edinburgh 102B

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inducers of lipid peroxidation in tissue slices Free Radical Biology and

Medicine 3 119-123

Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Giovanelli G and Pagliarini E (2009) Antioxidant composition of tomato

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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body fat Physiol Behav 94 164ndash8

Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

liver chemistry tests Gasteroenteerology 123 1367-1384

Grill V and Bjoumlrklund A (2009) Impact of metabolic abnormalities for

beta cell function clinical significance and underlying mechanisms Mol

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improvement for nutritional and health benefits Curr Opin Biotechnol 13

508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

Guumllccedilin I Mshvildadze VA Gepdiremen A and Elias R (2006) The

antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

Research 20 130ndash134

Gulcin Buyukokuroglu ME Oktay M and Kufrevioglu O (2003)

Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

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activities of peel pulp and seed fractions of common fruits as determined by

FRAP assay Nutrition Research 23 1719ndash1726

Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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superoxide in inflammation and immune regulation Journal of Physiology

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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and hepatoprotective effects of silibinin in a rat model of nonalcoholic

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Halliwell B (1993) The role of oxygen radicals in human disease with

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Halliwell B (1994) Free radicals antioxidants and human disease

curiosity cause or consequence Lancet 344 721ndash724

Halliwell B (1996) Antioxidants in human health and disease Annual

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Halliwell B (2000) Why and how should we measure oxidative DNA

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Halliwell B (2001) Role of free radicals in the neurodegenerative diseases

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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Halliwell B (2006) Reactive species and antioxidants Redox biology is a

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Halliwell B and Gutteridge JM (1995) The definition and measurement of

antioxidants in biological systems Free Radical Biol Med 18 125ndash126

Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

characterization of antioxidant Food Chem Toxicol 33 601-617

Halliwell B Gutteridge JM and Cross CE (1992) Free radicals

antioxidants and human disease where are we now J Lab Clin Med 119

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

method a simple test tube assay for determination of rate constants for

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Handa SS Sharma A and Charaborti KK (1986) Natural products and

plants as lives protecting drugs Fitoterpia 57 307-45

Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

Harada N Oda Z Hara Y Fujinami K Okawa M Ohbuchi K

Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harbrone JBC (1973) Phytochemical methods Chapman and Hall

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

JG Magee WP Dalvie DK Soliman VF Martin WH Mularski CJ

and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

treatment of metabolic syndrome Curr Opin Investig Drugs 5 283ndash289

Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

Hassan II Askar AA Gehan A EL-Shourbagy A (2004) Influence of

some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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Hedge JE and Hofreiter BT (1962) Detremination of reducing sugars

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Helader L M Alakomi H-L Latva-Kala K Mattila- Sandholm T Pol

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

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Hillwell B (1994) Free radicals antioxidants and human disease Curiosity

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Hirabara SM Silveira LR Abdulkader F Carvalho CR Procopio J

and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

metabolism J Cell Physiol 210 7ndash15

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106 1219-1228

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erythrocyte superoxide dismutase with hydrogen peroxide

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in vivo British Medical Bulletin 49 494ndash505

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Houghton P J Zarka R Heras B and Hoult JRS (1995) Fixed oil of

Nigella sativa and derived thymoquinone inhibit eicosanoid generation in

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Houstis N Rosen ED Lander ES (2006) Reactive oxygen species have

a causal role in multiple forms of insulin resistance Nature 440944ndash8

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22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

Food Chem 114 466ndash471

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

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Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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Khan MS Nema N Kharya MD and Khanam S (2009)

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

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Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

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King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

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Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

and Dosso M (2004) Traditional medicine in North Cocircte-DlsquoIvoire

Screening of 50 medicinal plants for antibacterial activity Journal of

Ethnopharmacology 93 43ndash49

Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

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insulin resistance compared with a standard murine high-fat diet Am J

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Korchak HM (1962) Regulation of hepatic lipogenesis Tufts Folia Med

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

of chemical composition and antifungal and antioxidant activities of the

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and Food Chemistry 53 1408ndash1416

Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

in patients with nonalcoholic steatohepatitis Journal of Clinical

Gastroenterology 37 177ndash182

Kotani K Peroni OD Minokoshi Y Boss O and Kahn BB (2004)

GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

Koteish A and Diehl AM (2002) Animal models of steatohepatitis Best

Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not

ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

Kowdley KV (2000) Ursodeoxycholic acid therapy in hepatobiliary

disease Am J Med 108 481ndash486

Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

resistance in high-fat-fed rats Diabetes 40 1397 ndash 1403

Kresge N Simoni RD and Hill RL (2006) Forty years of superoxide

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17-19

Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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7 330-338

Kroumltz F Sohn HY and Gloe T (2002) Oxidase-dependent platelet

superoxide anion release incrj5eases platelet recruitment Blood 100 917-

924

Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

mice inhibits neither the CDP-choline pathway for phosphatidylcholine

synthesis in hepatocytes nor apolipoprotein B secretion J Biol Chem 279

23916-23924

Kumar G Sharmila Banu G Kannan V and Rajasekarapandian M

(2005) Antihepatotoxic effect of β-carotene on paracetamol induced hepatic

damage in rats Indian J Exp Biol 43 351-355

Kumar V Rani A Dixit A K Pratap D and Bhatnagar D (2010) A

comparative assessment of total phenolic content ferric reducing-anti-

oxidative power free radical-scavenging activity vitamin C and isoflavones

content in soybean with varying seed coat colour Food Research

International 43 323minus328

Kumpulainen JT and Salonen JT (1999) Natural Antioxidants and

Anticarcinogens in Nutrition Health and Disease the Royal Society of

Chemistry UK 178-187

Kuo YH and Li YC (2000) Four new compounds ficusal

ficusesquilignan A B and ficusolide diacetate from the heartwood of Ficus

microcarpa Chemical and Pharmaceutical Bulletin 48 1862ndash1865

Kuriakose GC and Kurup GM (2008) Antioxidant activity of Aulosira

fertilisima on CCl4 induced hepatotoxicity in rats Indian J Exp Bio 46 52-

59

Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

Desmodium gangeticum (L) root protects rat heart against ischemic

reperfusion injury induced oxidative stress Indian J Exp Biol 47 129ndash35

Labhal A Settaf A Bennani N Cherrah Y Slaoui A and Hassar M

(1997) Action anti-obeacutesiteacute et hypocholesteacuteroleacutemiante de Nigella sativa chez

le rat des sables Caduceacutee 27 26ndash28

Labhal A Settaf A Zalagh F Cherrah Y Hassar M and Slaoui A

(1999) Proprieacuteteacutes anti-diabeacutetiques des graines de Nigella sativa chez le

Meriones shawi obegravese et diabeacutetique Espeacuterance Meacutedicale 47 72ndash74

Laemmli U K (1970) Cleavage of structural proteins during the assembly

of the head of bacteriophage T4 Nature 227 680-685

Lagiou P Samoli E and Lagiou A (2004) Intake of specific flavonoid

classes and coronary heart disease-a case-control study in Greece Eur J

Clin Nutr 58 (12) 1643ndash1648

Lai LS Chan ST and Chao WW (2001) Studies on the antioxidative

activities of mesona procumbers Hemsleaf gum J Agric Food Chem 19

963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

and Newmana B (2008) Ficus spp (fig) Ethnobotany and potential as

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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extracts for antioxidant activity Life Sci 73 167-179

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

type 2 diabetes Advanced Drug Delivery Reviews 54 1199ndash1212

Leung KK and Leung PS (2008) Effects of hyperglycemia on

angiotensin receptor type 1 expression and insulin secretion in an INS-1E

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Food Chemistry 53(1) 103minus110

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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results of a randomized trial Hepatology 39 770-8

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HO in vitro and in vivo Free Radical Biology and Medicine 16 29ndash36

Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

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Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

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Mayo Clin Proc 55434-438

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

Labaudiniere RF (1999) J Med Chem 42 3251e3264

Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

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genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

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Musso G Gambino R and Cassader M (2009) Recent insights into

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

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Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

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Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

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Rheediinosides A and B two antiproliferative and antioxidant triterpene

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Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

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(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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convenient substrate for determination and study of L-and D-glutamyl trans

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

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Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

Ethanopharmacology 91 99-104

Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

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Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Plant Foods for Human Nutrition 63(3) 127minus133

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Gastroenterology 123 1705ndash1725

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

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Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

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Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

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Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

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Am J Gastroenterol 99 1497ndash1502

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Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

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Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

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Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

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PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

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modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

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Preparation and Pharmacological evaluation of plant material England John

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Wink M (1999) Functions of plant secondary metabolites and their

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El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

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(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

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Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

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Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

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Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Liver 40th

di Elsevier 1858

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Gurumoorthy V Hindu Jan-23rd 2011

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Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

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Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

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Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

MJ and Weinrauch Y (2008) Reactive nitrogen species contribute to

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

Alonso-Villaverde C Aragones G Claria J and Camps J (2007) The

results in rodent models of atherosclerosis are not interchangeable the

influence of diet and strain Atherosclerosis 195 e85ndashe92

Juntachote T and Berghofer E (2005) Antioxidative properties and

stability of ethanolic extracts of Holy basil and Galangal Food Chem 92

193ndash202

Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

and spinal cord injury suggestions for pharmacological and nutritional

management strategies J Spinal Cord Med 21 309-334

Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

Kiyoshi Mizuguchi (2009) Suppression of hepatic fat accumulation by

highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

diet Biochimica et Biophysica Acta 1791 281ndash288

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spectrophotometric assay of superoxide dismutase Indian J

BiochemBiophys 21 130- 132

Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

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properties of tocopherols and tocotrienols Lipids 31 671-701

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(2000) Radio-protective properties of Asparagus racemosus in vitro in rat

liver mitochondria JEthanopharmacol 71 425-435

Kamboj VP (2000) Herbal medicine Curr Med 78 35-39

Kantartzis K Peter A Machicao F Machann J Wagner S

Koumlnigsrainer I Koumlnigsrainer A Schick F Fritsche A Haumlring HU

and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

59ndash75) London UK Taylor and Francis Press

Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

rats Phytotherapy Research 13(2) 95-101

Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

55 2824ndash8

Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

Experimental 35 655-657

Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

K (2005) Potential of sourdough for healthier cereal products Trends Food

Science and Technology 16 104ndash112

Katz D Mazor D Dvilansky A and Meyerstein N (1996) Effect of

radiation on red cell membrane and intracellular oxidative defense systems

Free Radical Research 24 199ndash204

Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

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teerpenoid diversity in the constitutive and induced defence of coniters

against insects and pathogens New Phytol 170 657-675

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

Ipomoea mauritiana 1 22-30

Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

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(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

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scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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system Ann Clin Lab Sci 30 145-158

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

Brief Scientific Literature Review Research Diets Inc 3000-2-09

Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

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Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Michalak A (2006) Phenolic compounds and their antioxidant activity in

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

formulation in galactosamine induced hepatopathy in rats Indian J Physiol

Pharmacol 44 82-86

Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

Mucuna pruriens Linn And formation containing Mpruriens by HPTLC

method Chem Pharma Bull 56(3) 357

Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

International Journal of Biotechnology amp Biochemistry 303-323

Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

Moncada A Palmaer RMJ and Higgs EA (1991) Nitric oxide

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1421

Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

Moron MS Bepierre JE and Vik BM (1979) Levels of glutathione

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Morris GM Goodsell DS Halliday RS Huey R Hart WE Belew

RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

algorithm and an empirical binding free energy function J Comput Chem

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Morrissey JP and Osbourn AE (1999) Fungal resistance to plant

antibiotics as a mechanism of pathogenesis Microbiological and Molecular

Biological Reviews 63 708-724

Moss DW and Butterorth PJ (1974) Enzymology and Medicine London

Pitman Medical 139

Mozaffari FS Ghorbani M Babai A and Farzami Sepehr M (2000)

The effect of water stress on the seed oil of Nigella sativa L J Essent Oil

Res 12 36-38

Mursu J Voutilainen S Nurmi T Tuomainen TP Kurl S and Salonen

JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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convenient substrate for determination and study of L-and D-glutamyl trans

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(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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tissue growth factor expression a potential mechanism involved in

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

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Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

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peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

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Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

actions of LDOPA and dopamine in vitro implications for Parkinsons

disease Free Radical Research 24 95-105

Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

Exp Geront 36 1425-1457

Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

218

Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

Chemical Society Washington DC 223

Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

liver diseases Digestive and liver Disease 39 (4) 293-304

Stief TW (2003) The physiology and pharmacology of singlet oxygen

Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

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El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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Emery MG Fisher JM and Chien JY (2003) CYP2E1 activity before

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Enriquez A Leclercq I Farrell GC and Robertson G (1999) Altered

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Evans P and Halliwell B (1999) Free radicals and hearing Cause

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Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

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Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

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Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

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in the calculation of electrostatic solvation energies for protein structures

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PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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Fraga C Leibovitz B and Tappel A (1987a) Halogenated compounds as

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Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

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Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

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Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

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Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Gray (2008) Anatomy The Anatomical basis of clinical practice Chap 68

Liver 40th

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Green RM and Flamm S (2002) AGA Technical review of evaluation of

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508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

Guumllccedilin I Mshvildadze VA Gepdiremen A and Elias R (2006) The

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Gulcin Buyukokuroglu ME Oktay M and Kufrevioglu O (2003)

Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

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Guo C Yang J Wei J Li Y Xu J and Jiang Y (2003) Antioxidant

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Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

Guzik TJ Korbut R and Adamek-Guzik T (2003) Nitric oxide and

superoxide in inflammation and immune regulation Journal of Physiology

and Pharmacology 54 (4) 469-487

Gyamfi MA Yonamine M and Aniya Y (1999) Free-radical scavenging

action of medicinal herbs from Ghana Thonningia sanguine on

experimentally induced liver injuries General Pharmacol 32 661-667

Habig WH Pabst MJ and Jacob WB (1974) Glutathione-S-transferase

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7130-7139

Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

Haddad Y Vallerand D Brault A and Haddad PS (2009) Antioxidant

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Halliwell B (1977) Generation of hydrogen peroxide superoxide and

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Halliwell B (1991) Reactive oxygen species in living systems source

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91(suppl 3C) 14Sndash22S

Halliwell B (1993) The role of oxygen radicals in human disease with

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curiosity cause or consequence Lancet 344 721ndash724

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Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

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some medicinal plants on performances physiological and meat quality traits

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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changes in microheological properties of the red cell membrane 76 1015-

1022

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Methods in Carbohydrate chemistry ML Academic Press New York 1

388-389

Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

Linn root extract against CCl4 and paracetamol induced hepatic oxidative

stress Indian Journal of Experimental Biology 47 660-667

Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

in rats African Journal of Biochemistry 2(6) 141-144

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Chem46 3590

Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

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Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

selectivity Cancer Chemother Pharmacol 53 209ndash19

Hillwell B (1994) Free radicals antioxidants and human disease Curiosity

cause or constipation Lancet 344 721-724

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and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

metabolism J Cell Physiol 210 7ndash15

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106 1219-1228

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erythrocyte superoxide dismutase with hydrogen peroxide

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in vivo British Medical Bulletin 49 494ndash505

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determination of free fatty acids in plasma J Lipid Res 22 377-381

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Nigella sativa and derived thymoquinone inhibit eicosanoid generation in

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a causal role in multiple forms of insulin resistance Nature 440944ndash8

httpclinicaltrialsgovct2showNCT00065676intrfrac1422quercetin

22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

extract suppresses both reactive oxygen species and nitric oxide and prevents

lipid oxidation in vitro Phytomedicine 12 588ndash597

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capacity assays Journal of Agricultural and Food Chemistry 53(6)

1841minus1856

Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

scientific review Journal of American Medical Association 287 360ndash372

Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

MJ and Weinrauch Y (2008) Reactive nitrogen species contribute to

innate host defense against Camoylobacter jjuni Infection and Immunity

76(3) 986-93

Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

Food Chem 114 466ndash471

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15 755-766

Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

Hepatoprotective activity of ethanolic and aqueous extract of Amorphallus

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WB (ed) Enzymatic Basis of Detoxification Academic press New York

63-94

James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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parameters in rats fed with cholesterol-free and cholesterolenriched diets

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cancers of the alimentary tract Mutation Research 551(1ndash2) 9minus28

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

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results in rodent models of atherosclerosis are not interchangeable the

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stability of ethanolic extracts of Holy basil and Galangal Food Chem 92

193ndash202

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and spinal cord injury suggestions for pharmacological and nutritional

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Kiyoshi Mizuguchi (2009) Suppression of hepatic fat accumulation by

highly purified eicosapentaenoic acid prevents the progression of D-

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diet Biochimica et Biophysica Acta 1791 281ndash288

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proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

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properties of tocopherols and tocotrienols Lipids 31 671-701

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Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Biochem pharmacol 32 1141-1148

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Chromatographic estimation of maturity based phytochemical profiling of

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Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

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Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

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963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

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Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

sativa oil against the liver damage induced by Shistosoma mansoni infection

in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

Malik EP Singh MB (1980) Plant Enzymology and Hittoenzymology

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

GK (2007) Phytochemical Studies of Strychnos potatorum LF A

Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

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morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

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investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

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anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

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patients Nutr Rev 58 278-281

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biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

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and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

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radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

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Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

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Rao KS (2009) Free radical induced oxidative damage to DNA relation to

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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decolorisation assay Free Radical Biol Med 26 1231-1237

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Richter C (1987) Biophysical consequences of lipid peroxidation in

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Robak J Gryglewski RJ (1988) Flavonoids are scavengers of superoxide

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species as the mechanism of drug action Polish J of Pharmacol 47 89-98

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organization of biomolecules American Mineralogist 91 1715ndash1729

Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

Vaziri ND (2006) Oxidative stress and dysregulation of NAD(P)H oxidase

and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

(5) G1135ndashG1139

Roe J H and Keuther C A (1943) The determination of ascorbic acid in

whole blood and urine through 2 4-dinitro phenyl hydrazine derivative of

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Rohrdanz E Schmuck G Ohler S and Kahl R (2001) The influence of

oxidative stress on catalase and MnSOD gene transcription in astrocytes

Brain Res 900 128-136

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dcrease in lipid peroxidation after vitamin E dietary supplementation in

guinea pigs Free Radic Biol Med 21 907-15

Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

fermented with Saccharomyces cerevisiae Eur J Lipid Sci Technol 106

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with signs and symptoms of liver disease In clinical practice of

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

Roy S Sehgal R Pahdy BM and Kumar VL (2005) Antioxidant and

protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

(2008) Micellarisation of carotenoids from raw and cooked vegetables

Plant Foods for Human Nutrition 63(3) 127minus133

Sadasivam S Manickam A (1997) Biochemical methods Second edition

Newage international Pvt Ltd

Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

(2004) Up regulation of osteopontin expression is involved in the

development of non-alcoholic steatohepatitis in a dietary murine model Am

J Physiol Gastrointest Liver Physiol 287 G264-G273

Sahreen S Rashid Khan M and Ali Khan R (2010) Evaluation of

antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

RK (2002) Antiulcerogenic activity of methanolic extract of Emblica

Officinalis Journal of Ethanopharmacology 82 1-9

Sallie R Tredgr JM and William (1999) Drugs and the liver Biopharm

Drug Dispos 12 251-259

Salom S M Gray J A Alford A R Mulesky M Fettig C J and

Woods S A (1996) J Entomol Sci 31 453

Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

AJ and Shulman GI (2004) Mechanism of hepatic insulin resistance in

non-alcoholic fatty liver disease J Biol Chem 279 32345-32353

Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

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Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

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Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

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alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

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Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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El-Dakhakhny M Mady NI and Halim M (2000) Nigella sativa L oil

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livers disease Hepatology 38 428ndash 35

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expression of hepatic CYP2E1 and CYP4A in obese diabetic obob mice

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Esterbauer H Schaur RJ and Zollner H (1991) Chemistry and

biochemistry of 4-hydroxynonenal malonaldehyde and related aldehydes

Free Radical Biology amp Medicine 11 (1) 81ndash128

Evans P and Halliwell B (1999) Free radicals and hearing Cause

consequence and criteria Ann N Y Acad Sci 884 19-40

Fan JG Zhu J and Li XJ (2005) Fatty liver and the metabolic syndrome

among Shanghai adults J Gastroenterol Hepatol 20 1825-32

Fang YZ Yang S and Wu G (2002) Free radicals antioxidants and

nutrition Nutrition 18 872-879

Fardet A Llorach R Martin JF Besson C Lyan B Pujos-Guillot E

and Scalbert A (2008) Aliquid chromatographyndashquadrupole time-of-flight

(LCndashQTOF)-based metabolomic approach reveals new metabolic effects of

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Farrel GC Larter CZ (2006) Nonalcoholic fatty liver disease from

steatosis to cirrhosis Hepatology 43S99ndash112

Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

(2004) Performance comparison of generalized born and Poisson methods

in the calculation of electrostatic solvation energies for protein structures

Journal of Computational Chemistry 25 (2) 265ndash84 doi101002jcc10378

PMID 14648625

Feldstein AEWerneburg NW Canbay A Guicciardi ME Bronk

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promote hepatic lipotoxicity by stimulating TNF-alpha expression via a

lysosomal pathway Hepatology 40 185ndash194

Ferannini E Natalie A and Bell P (1997)Insulin resistance and

hypersecretion in obesity J Clin Invest 100 1166

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Foyer CH and Halliwell B (1976) The presence of glutathione activation

during plant stress Proceedings of the Royal Society of Edinburgh 102B

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inducers of lipid peroxidation in tissue slices Free Radical Biology and

Medicine 3 119-123

Francis G Kerem Z Makkar HPS and Becker K (2002) The

biological action of saponins in animal systems a review British Journal of

Nutrition 88 587ndash605

Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

vivo evidence from animal studies J Nutr 133 3275Sndash84S

Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

(2004) The ins and outs of mitochondrial dysfunction in NASH Diabetes amp

Metabolism 30 121ndash138

Fruhwirth GO Loidl A and Hermetter A (2007) Oxidized

phospholipids From molecular properties to disease Biochem Biophys

Acta 1772 718-736

Fryer MJ (1992) The antioxidant effects of thyla Vit E Plant cell Environ

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Ganapathy S (2004) Emerging strategy in the study of natural products

Indian Journal of

Germano MP Sanogo R Costa C Fulco R Ando DV Torrel EA

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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body fat Physiol Behav 94 164ndash8

Grattagliano I Caraceni P Calamita G Ferri D Gargano I Palasciano

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Liver 40th

di Elsevier 1858

Green RM and Flamm S (2002) AGA Technical review of evaluation of

liver chemistry tests Gasteroenteerology 123 1367-1384

Grill V and Bjoumlrklund A (2009) Impact of metabolic abnormalities for

beta cell function clinical significance and underlying mechanisms Mol

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improvement for nutritional and health benefits Curr Opin Biotechnol 13

508ndash511

Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

Antioxidant activity of saponins isolated from ivy a-hederin hederasaponin-

C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

Guumllccedilin I Mshvildadze VA Gepdiremen A and Elias R (2006) The

antioxidant activity of a triterpenoid glycoside isolated from the berries of

Hedera colchica 3-O-(b-D-glucopyranosyl)-hederagenin Phytotherapy

Research 20 130ndash134

Gulcin Buyukokuroglu ME Oktay M and Kufrevioglu O (2003)

Antioxidant and analgesic activities of turpentine of Pinus nigra Arn Subsp

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activities of peel pulp and seed fractions of common fruits as determined by

FRAP assay Nutrition Research 23 1719ndash1726

Gupta R and Misra A (2007) Type 2 diabetes in India regional

disparities Br J Diab Vasc Dis 7(1)12ndash6

Gurumoorthy V Hindu Jan-23rd 2011

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superoxide in inflammation and immune regulation Journal of Physiology

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

Two new biologically active triterpenoidal saponins acylated with salicylic

acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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91(suppl 3C) 14Sndash22S

Halliwell B (1993) The role of oxygen radicals in human disease with

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Halliwell B (1994) Free radicals antioxidants and human disease

curiosity cause or consequence Lancet 344 721ndash724

Halliwell B (1996) Antioxidants in human health and disease Annual

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Halliwell B (2001) Role of free radicals in the neurodegenerative diseases

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Halliwell B (2002) Effect of diet on cancer development is oxidative DNA

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Halliwell B (2006) Reactive species and antioxidants Redox biology is a

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antioxidants in biological systems Free Radical Biol Med 18 125ndash126

Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and

Medicine Oxford Oxford University Press 347ndash352

Halliwell B Aeschbach R Loliger J and Aruoma OI (1995) The

characterization of antioxidant Food Chem Toxicol 33 601-617

Halliwell B Gutteridge JM and Cross CE (1992) Free radicals

antioxidants and human disease where are we now J Lab Clin Med 119

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Halliwell B Gutteridge MC and Aruoma OI (1987) The deoxyribose

method a simple test tube assay for determination of rate constants for

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plants as lives protecting drugs Fitoterpia 57 307-45

Hansson A Zelada JC and Noriega HP (2005) Revaluations of risks

with the use of Ficus insipid latex as a traditional anthelmintic remedy in the

Amazon Journal of Ethnopharmacology 98 251ndash257

Harada N Oda Z Hara Y Fujinami K Okawa M Ohbuchi K

Yonemoto M Ikeda Y Ohwaki K Aragane K Tamai Y Kusunoki

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Harbrone JBC (1973) Phytochemical methods Chapman and Hall

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Harrison P Degen SJ Williams R and Farzaneh F (1994) Hepatic

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mRNA in fulminant hepatic failure Lancet 344 27ndash29

Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

Makowski MR Hargrove DM Martin KA Tracey WR Chapman

JG Magee WP Dalvie DK Soliman VF Martin WH Mularski CJ

and Eisenbeis SA (2003) J Biol Chem 278 37099

Harwood H J Jr (2004) Acetyl-CoA carboxylase inhibition for the

treatment of metabolic syndrome Curr Opin Investig Drugs 5 283ndash289

Harwood HJ Jr Exp Opin Cardiovasc Renal (2005) 9 267

Hassan II Askar AA Gehan A EL-Shourbagy A (2004) Influence of

some medicinal plants on performances physiological and meat quality traits

of broiler chicks Egypt Poult Sci 24 247ndash266

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associated with hyperlipidemia caused by a semi-synthetic diet Laboratory

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Hawkins CL Brown BE and Davies MJ (2001) Hypochlorite- and

hypobromite-mediated radical formation and its role in cell lysis Arch

Biochem Biophys 395 137-145

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Hedge JE and Hofreiter BT (1962) Detremination of reducing sugars

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heibatollah S Reza NM Izadpanah G and Sohailla S (2008)

Hepatoprotective effect of Cichorium intybus on CCl4 induced liver damage

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Helader L M Alakomi H-L Latva-Kala K Mattila- Sandholm T Pol

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

Conjugates of ursodeoxycholate protect against cytotoxicity of more

hydrophobic bile salts Hepatology 14 920ndash926

Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty

liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

Intrinsic oxidative stress in cancer cells a biochemical basis for therapeutic

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Hillwell B (1994) Free radicals antioxidants and human disease Curiosity

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Hirabara SM Silveira LR Abdulkader F Carvalho CR Procopio J

and Curi R (2007) Time-dependent effects of fatty acids on skeletal muscle

metabolism J Cell Physiol 210 7ndash15

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106 1219-1228

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erythrocyte superoxide dismutase with hydrogen peroxide

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in vivo British Medical Bulletin 49 494ndash505

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Nigella sativa and derived thymoquinone inhibit eicosanoid generation in

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Houstis N Rosen ED Lander ES (2006) Reactive oxygen species have

a causal role in multiple forms of insulin resistance Nature 440944ndash8

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22amprankfrac145 (accessed 170609)

Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

Food Chem 114 466ndash471

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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highly purified eicosapentaenoic acid prevents the progression of D-

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Kakkar P Das B and Vishwanathan P N (1984) A modified

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

nonalcoholic fatty liver disease World J Gastroenterol 1422ndash8

Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

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Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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Khan MS Nema N Kharya MD and Khanam S (2009)

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

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Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

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King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Medicinal Chemistry 24(2) 395minus405

Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

and Dosso M (2004) Traditional medicine in North Cocircte-DlsquoIvoire

Screening of 50 medicinal plants for antibacterial activity Journal of

Ethnopharmacology 93 43ndash49

Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

feeding results in higher serum alanine aminotransferase and increased

insulin resistance compared with a standard murine high-fat diet Am J

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Korchak HM (1962) Regulation of hepatic lipogenesis Tufts Folia Med

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

of chemical composition and antifungal and antioxidant activities of the

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and Food Chemistry 53 1408ndash1416

Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

in patients with nonalcoholic steatohepatitis Journal of Clinical

Gastroenterology 37 177ndash182

Kotani K Peroni OD Minokoshi Y Boss O and Kahn BB (2004)

GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

Koteish A and Diehl AM (2002) Animal models of steatohepatitis Best

Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not

ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

Kowdley KV (2000) Ursodeoxycholic acid therapy in hepatobiliary

disease Am J Med 108 481ndash486

Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

resistance in high-fat-fed rats Diabetes 40 1397 ndash 1403

Kresge N Simoni RD and Hill RL (2006) Forty years of superoxide

dismutase research the work of irwin fridovich [J] J Biol Chem 281(22)

17-19

Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

(2007) Antihyperglycemic and antilipidperoxidative effects of Ficus

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7 330-338

Kroumltz F Sohn HY and Gloe T (2002) Oxidase-dependent platelet

superoxide anion release incrj5eases platelet recruitment Blood 100 917-

924

Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

mice inhibits neither the CDP-choline pathway for phosphatidylcholine

synthesis in hepatocytes nor apolipoprotein B secretion J Biol Chem 279

23916-23924

Kumar G Sharmila Banu G Kannan V and Rajasekarapandian M

(2005) Antihepatotoxic effect of β-carotene on paracetamol induced hepatic

damage in rats Indian J Exp Biol 43 351-355

Kumar V Rani A Dixit A K Pratap D and Bhatnagar D (2010) A

comparative assessment of total phenolic content ferric reducing-anti-

oxidative power free radical-scavenging activity vitamin C and isoflavones

content in soybean with varying seed coat colour Food Research

International 43 323minus328

Kumpulainen JT and Salonen JT (1999) Natural Antioxidants and

Anticarcinogens in Nutrition Health and Disease the Royal Society of

Chemistry UK 178-187

Kuo YH and Li YC (2000) Four new compounds ficusal

ficusesquilignan A B and ficusolide diacetate from the heartwood of Ficus

microcarpa Chemical and Pharmaceutical Bulletin 48 1862ndash1865

Kuriakose GC and Kurup GM (2008) Antioxidant activity of Aulosira

fertilisima on CCl4 induced hepatotoxicity in rats Indian J Exp Bio 46 52-

59

Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

Desmodium gangeticum (L) root protects rat heart against ischemic

reperfusion injury induced oxidative stress Indian J Exp Biol 47 129ndash35

Labhal A Settaf A Bennani N Cherrah Y Slaoui A and Hassar M

(1997) Action anti-obeacutesiteacute et hypocholesteacuteroleacutemiante de Nigella sativa chez

le rat des sables Caduceacutee 27 26ndash28

Labhal A Settaf A Zalagh F Cherrah Y Hassar M and Slaoui A

(1999) Proprieacuteteacutes anti-diabeacutetiques des graines de Nigella sativa chez le

Meriones shawi obegravese et diabeacutetique Espeacuterance Meacutedicale 47 72ndash74

Laemmli U K (1970) Cleavage of structural proteins during the assembly

of the head of bacteriophage T4 Nature 227 680-685

Lagiou P Samoli E and Lagiou A (2004) Intake of specific flavonoid

classes and coronary heart disease-a case-control study in Greece Eur J

Clin Nutr 58 (12) 1643ndash1648

Lai LS Chan ST and Chao WW (2001) Studies on the antioxidative

activities of mesona procumbers Hemsleaf gum J Agric Food Chem 19

963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

and Newmana B (2008) Ficus spp (fig) Ethnobotany and potential as

anticancer and anti-inflammatory agents Journal of Ethnopharmacology

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Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

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steatohepatitis Hepatology 39(5) 1277-1285

Laurin J Lindor KD Crippin JS Gossard A Gores GJ Ludwig J

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23 1464ndash1467

Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

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Ethnopharmacology 94 251ndash259

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CYP4A in leptin-deficient obob mice Biochim Biophys Res Commun 268

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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extracts for antioxidant activity Life Sci 73 167-179

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

type 2 diabetes Advanced Drug Delivery Reviews 54 1199ndash1212

Leung KK and Leung PS (2008) Effects of hyperglycemia on

angiotensin receptor type 1 expression and insulin secretion in an INS-1E

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Food Chemistry 53(1) 103minus110

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pathological role Physiol Rev 77 517ndash 44

Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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results of a randomized trial Hepatology 39 770-8

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HO in vitro and in vivo Free Radical Biology and Medicine 16 29ndash36

Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

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Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

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Mayo Clin Proc 55434-438

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

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Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

Labaudiniere RF (1999) J Med Chem 42 3251e3264

Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

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Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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risk factor study Br J Nutr 100 (4) 890ndash895

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

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Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

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Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Molecular Biology 49 249-279

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Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

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Rheediinosides A and B two antiproliferative and antioxidant triterpene

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acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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convenient substrate for determination and study of L-and D-glutamyl trans

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

Sci 5 445-459

Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

Ethanopharmacology 91 99-104

Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

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Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Gastroenterology 123 1705ndash1725

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

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Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

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Van den Berg R Haenen GRMM Van den Berg H and Bast A

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Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

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Am J Gastroenterol 99 1497ndash1502

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Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

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Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

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Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

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PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

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modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

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Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

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Preparation and Pharmacological evaluation of plant material England John

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Wink M (1999) Functions of plant secondary metabolites and their

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Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

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Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

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Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

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Feig M Onufriev A Lee MS Im W Case DA and Brooks CL

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Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in

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Fromenty B Robin MA Igoudjil A Mansouri A and Pessayre D

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Girish S Achliya Sudhir Wadodkar G Avinash and Dorle K (2004)

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di Elsevier 1858

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Guumllccedilin I Mshvildadze V Gepdiremen A and Elias R (2004)

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C hederacolchiside-E and hederacolchiside-F Planta Medica 70 561ndash563

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Gurumoorthy V Hindu Jan-23rd 2011

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Haddad M Miyamoto T Laurens V and Lacaille-Dubois MA (2003)

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acid from Albizia adianthifolia Journal of Natural Products 66 372ndash377

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Harvey AL (2008) Drug Discov Today 13 894e901

Harwood H J Jr Petras SF Shelly LD Zaccaro LM Perry DA

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

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and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

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Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

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Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

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Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

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Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

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Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

oxidative damage response in Wistar rats Life Sciences 77 1194ndash1210

Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

al The role of oxidative stress in non-alcoholic steatohepatitis Clin Chim

Acta (2011) doi101016jcca201104013

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antioxidant activity of silymarin Journal of Enzyme Inhibition and

Medicinal Chemistry 24(2) 395minus405

Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Screening of 50 medicinal plants for antibacterial activity Journal of

Ethnopharmacology 93 43ndash49

Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

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GLUT4 glucose transporter deficiency increases hepatic lipid production and

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ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

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Anticarcinogens in Nutrition Health and Disease the Royal Society of

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963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

and Newmana B (2008) Ficus spp (fig) Ethnobotany and potential as

anticancer and anti-inflammatory agents Journal of Ethnopharmacology

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

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Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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angiotensin receptor type 1 expression and insulin secretion in an INS-1E

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Food Chemistry 53(1) 103minus110

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

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Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mayo Clin Proc 55434-438

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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genotypes under stress of different concentrations of sucrose and sorbito

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

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metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

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Progress in Lipid Research 48 1e26

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relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

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preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

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Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

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Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

composition of the fixed and volatile oils of Nigella Sativa L Zeitschrift for

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Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

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Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

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and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

Seeds Food Chem 106 760-766

Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

OConnell OF Ryan L and OBrien NM (2007) Xanthophyll

carotenoids are more bioaccessible from fruits than dark green vegetables

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Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

fruits mixtures used in the treatment of diabtes AfrJBiotechnol 7(6) 701-

705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

Portois L and Chardigny JM (2006) Alteration of adipocyte metabolism

in omega3 fatty acid-depleted rats Horm Metab Res 38 789-798

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Okada Y Shibata S Ikekawa T Javellana AMJ and Kamo O (1987)

Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

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Acta Chromatographica 19 253-269

Orolowski M and Meister (1963) γ-glutamyl-p-nitroanilide a new

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Postharvest Biochemistry of Plant Food-Materials in Tropics Japan

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

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85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

Reitman S Frankel S (1957) Amer JClin Path 2856

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

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polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

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liver disease Hepatol Res 38(11) 1122ndash9

Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

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and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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Jollow DJ and McMillan DC (2001) Oxidative stress glucose-6-

phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

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Kakkar P Das B and Vishwanathan P N (1984) A modified

spectrophotometric assay of superoxide dismutase Indian J

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

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Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kantartzis K Peter A Machicao F Machann J Wagner S

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Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

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Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

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Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

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teerpenoid diversity in the constitutive and induced defence of coniters

against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

Ipomoea mauritiana 1 22-30

Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

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scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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system Ann Clin Lab Sci 30 145-158

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Rev Biochem 58 195ndash221

Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Acta (2011) doi101016jcca201104013

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Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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lipid-lowering and insulin-sensitizing actions in the rat Journal of

Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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supplementation retards early progression of arteriosclerosis in heart

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Michael Metz (2005) Liver function tests IMVS News letter 57

Michalak A (2006) Phenolic compounds and their antioxidant activity in

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

formulation in galactosamine induced hepatopathy in rats Indian J Physiol

Pharmacol 44 82-86

Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

Mucuna pruriens Linn And formation containing Mpruriens by HPTLC

method Chem Pharma Bull 56(3) 357

Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

International Journal of Biotechnology amp Biochemistry 303-323

Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

Moncada A Palmaer RMJ and Higgs EA (1991) Nitric oxide

physiology pathophysiology and pharmacology Pharmacol Rev 43 109-

1421

Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

Moron MS Bepierre JE and Vik BM (1979) Levels of glutathione

glutathione reductase and glutathione-S-transferase activities in rat lung and

liver Biochem Biophys Acta 582 3170-3185

Morris GM Goodsell DS Halliday RS Huey R Hart WE Belew

RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

algorithm and an empirical binding free energy function J Comput Chem

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Morrissey JP and Osbourn AE (1999) Fungal resistance to plant

antibiotics as a mechanism of pathogenesis Microbiological and Molecular

Biological Reviews 63 708-724

Moss DW and Butterorth PJ (1974) Enzymology and Medicine London

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Mozaffari FS Ghorbani M Babai A and Farzami Sepehr M (2000)

The effect of water stress on the seed oil of Nigella sativa L J Essent Oil

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Mursu J Voutilainen S Nurmi T Tuomainen TP Kurl S and Salonen

JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

Nadakarni KM (1976) Corcus sativus Nigella sativa In Nadkarni KM

(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

411

Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

composition of the fixed and volatile oils of Nigella Sativa L Zeitschrift for

Naturforschung 629-631

Nield and Pearson Burtis CA and Ashwood A (1963) In Text Book of

Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

reperfusion injury Br J Surg 91(2) 184-190

Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

Noguchi N Damiani E Greci L and Niki E (1999) Action of quinolinic

and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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antioxidant vitamins and trace elements supplemented diets on activities of

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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the hamster The Journal of Clinical Investigation 81 300ndash309

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

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Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

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and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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193ndash202

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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highly purified eicosapentaenoic acid prevents the progression of D-

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

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Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

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Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kamboj VP (2000) Herbal medicine Curr Med 78 35-39

Kantartzis K Peter A Machicao F Machann J Wagner S

Koumlnigsrainer I Koumlnigsrainer A Schick F Fritsche A Haumlring HU

and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

59ndash75) London UK Taylor and Francis Press

Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

rats Phytotherapy Research 13(2) 95-101

Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

55 2824ndash8

Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

Experimental 35 655-657

Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

K (2005) Potential of sourdough for healthier cereal products Trends Food

Science and Technology 16 104ndash112

Katz D Mazor D Dvilansky A and Meyerstein N (1996) Effect of

radiation on red cell membrane and intracellular oxidative defense systems

Free Radical Research 24 199ndash204

Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

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teerpenoid diversity in the constitutive and induced defence of coniters

against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

Ipomoea mauritiana 1 22-30

Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

oxidative damage response in Wistar rats Life Sciences 77 1194ndash1210

Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

clinical enzymology (Ed Van D) London Nostrond Company Limited

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dehydrogenase In Practical Clinical Enzymology (Ed Van D) London

Nostrond Company Limited 83

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scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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system Ann Clin Lab Sci 30 145-158

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Acta (2011) doi101016jcca201104013

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Medicinal Chemistry 24(2) 395minus405

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Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

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963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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anticancer and anti-inflammatory agents Journal of Ethnopharmacology

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Laurin J Lindor KD Crippin JS Gossard A Gores GJ Ludwig J

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

lipid-lowering and insulin-sensitizing actions in the rat Journal of

Ethnopharmacology 94 251ndash259

Leclercq I Field J Erriquez A Farrell GC (2007) Robertson G

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Lee KW Everts H Kappert HJ Yeom KH and Beynen AC (2003)

Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Leung KK and Leung PS (2008) Effects of hyperglycemia on

angiotensin receptor type 1 expression and insulin secretion in an INS-1E

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Food Chemistry 53(1) 103minus110

Lieber CS (1997) Cytochrome P-4502E1 its physiological and

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

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Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Luck H (1974) In Methods in enzymatic analysisBer Acad N Y 885

Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

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Mayo Clin Proc 55434-438

Lugasi A Dworschak E Blazovics A and Kery A (1998) Antioxidant

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

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Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

sativa oil against the liver damage induced by Shistosoma mansoni infection

in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

Formosana J Sci Food Agric 88

Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

Rev 21 585e618

Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

Brief Scientific Literature Review Research Diets Inc 3000-2-09

Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

Mayes AP (1993) Structure and function of the lipid soluble vitamins In

Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

glutathione transferase activities in the human artery vein and heart J Mol

Cell Cardiol 22 935-938

Michael Metz (2005) Liver function tests IMVS News letter 57

Michalak A (2006) Phenolic compounds and their antioxidant activity in

plants growing under heavy metal stress Polish J Environ Studies 15(4)

523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

formulation in galactosamine induced hepatopathy in rats Indian J Physiol

Pharmacol 44 82-86

Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

Mucuna pruriens Linn And formation containing Mpruriens by HPTLC

method Chem Pharma Bull 56(3) 357

Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

International Journal of Biotechnology amp Biochemistry 303-323

Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

Moncada A Palmaer RMJ and Higgs EA (1991) Nitric oxide

physiology pathophysiology and pharmacology Pharmacol Rev 43 109-

1421

Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

Moron MS Bepierre JE and Vik BM (1979) Levels of glutathione

glutathione reductase and glutathione-S-transferase activities in rat lung and

liver Biochem Biophys Acta 582 3170-3185

Morris GM Goodsell DS Halliday RS Huey R Hart WE Belew

RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

algorithm and an empirical binding free energy function J Comput Chem

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Morrissey JP and Osbourn AE (1999) Fungal resistance to plant

antibiotics as a mechanism of pathogenesis Microbiological and Molecular

Biological Reviews 63 708-724

Moss DW and Butterorth PJ (1974) Enzymology and Medicine London

Pitman Medical 139

Mozaffari FS Ghorbani M Babai A and Farzami Sepehr M (2000)

The effect of water stress on the seed oil of Nigella sativa L J Essent Oil

Res 12 36-38

Mursu J Voutilainen S Nurmi T Tuomainen TP Kurl S and Salonen

JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

Nadakarni KM (1976) Corcus sativus Nigella sativa In Nadkarni KM

(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

411

Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Lipids 99 11-19

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

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carotenoids are more bioaccessible from fruits than dark green vegetables

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acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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705

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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convenient substrate for determination and study of L-and D-glutamyl trans

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Postharvest Biochemistry of Plant Food-Materials in Tropics Japan

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

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actions of LDOPA and dopamine in vitro implications for Parkinsons

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Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

Exp Geront 36 1425-1457

Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Stief TW (2003) The physiology and pharmacology of singlet oxygen

Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

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Lea amp Febiger

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

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Hileman EO Liu J Albitar M Keating MJ and Huang P (2004)

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

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Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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Commun 106 37-43

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193ndash202

Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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highly purified eicosapentaenoic acid prevents the progression of D-

galactosamine-induced hepatitis in mice fed with a high-fathigh-sucrose

diet Biochimica et Biophysica Acta 1791 281ndash288

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

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Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

properties of tocopherols and tocotrienols Lipids 31 671-701

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Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

K (2005) Potential of sourdough for healthier cereal products Trends Food

Science and Technology 16 104ndash112

Katz D Mazor D Dvilansky A and Meyerstein N (1996) Effect of

radiation on red cell membrane and intracellular oxidative defense systems

Free Radical Research 24 199ndash204

Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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and profound elevation of serum alanine aminotransferase in healthy

subjects Gut 57 649ndash654

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teerpenoid diversity in the constitutive and induced defence of coniters

against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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cancer chemoprevention J Cell Biochem 26s 1ndash28

Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

Ipomoea mauritiana 1 22-30

Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

oxidative damage response in Wistar rats Life Sciences 77 1194ndash1210

Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

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scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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system Ann Clin Lab Sci 30 145-158

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Cell Cardiol 22 935-938

Michael Metz (2005) Liver function tests IMVS News letter 57

Michalak A (2006) Phenolic compounds and their antioxidant activity in

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

formulation in galactosamine induced hepatopathy in rats Indian J Physiol

Pharmacol 44 82-86

Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

Mucuna pruriens Linn And formation containing Mpruriens by HPTLC

method Chem Pharma Bull 56(3) 357

Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

International Journal of Biotechnology amp Biochemistry 303-323

Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

Moncada A Palmaer RMJ and Higgs EA (1991) Nitric oxide

physiology pathophysiology and pharmacology Pharmacol Rev 43 109-

1421

Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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liver Biochem Biophys Acta 582 3170-3185

Morris GM Goodsell DS Halliday RS Huey R Hart WE Belew

RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

algorithm and an empirical binding free energy function J Comput Chem

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Morrissey JP and Osbourn AE (1999) Fungal resistance to plant

antibiotics as a mechanism of pathogenesis Microbiological and Molecular

Biological Reviews 63 708-724

Moss DW and Butterorth PJ (1974) Enzymology and Medicine London

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Mozaffari FS Ghorbani M Babai A and Farzami Sepehr M (2000)

The effect of water stress on the seed oil of Nigella sativa L J Essent Oil

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Mursu J Voutilainen S Nurmi T Tuomainen TP Kurl S and Salonen

JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

Nadakarni KM (1976) Corcus sativus Nigella sativa In Nadkarni KM

(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

411

Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

composition of the fixed and volatile oils of Nigella Sativa L Zeitschrift for

Naturforschung 629-631

Nield and Pearson Burtis CA and Ashwood A (1963) In Text Book of

Clinical Chemistry Chap27 Oxford Press New York 1280-1282

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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diabetes Science 306457ndash61

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

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Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Antioxidant properties of polyphenol-containing extract from soybean

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Nonalcoholic steatohepatitis association of insulin resistance and

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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the hamster The Journal of Clinical Investigation 81 300ndash309

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

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Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

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Hedge K Joshi AB (2009) Hepatoprotective effect of Carissa carandus

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Heuman DM Pandak WM Hylemon PB and Vlahzevic ZR (1991)

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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Jakoby WB and Habig WH (1998) Glutathione transferases In Jakoby

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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193ndash202

Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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Kajikawa S Tsuyoshi Harada Akiko Kawashima Kazunori Imada and

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

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Kamal-Eldin A and Appelqvist LA (1996) The chemistry and antioxidant

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Kamat JP Boloor KK Devasagayam TPA and Venkatachalam SR

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Kamboj VP (2000) Herbal medicine Curr Med 78 35-39

Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

Kappus H (1991) Lipid peroxidation-mechanism and biological relevance

In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

59ndash75) London UK Taylor and Francis Press

Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Free Radical Research 24 199ndash204

Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

Nystrom FH (2008) Fast-food-based hyper-alimentation can induce rapid

and profound elevation of serum alanine aminotransferase in healthy

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Keeling CI and Bohlmann J (2006) Genes enzymes and chemicals of

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against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

Technol Int 9 383

Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

LA Maolone WF Hawk ET and Sigman CC (1996) New agents for

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Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

oxidative damage response in Wistar rats Life Sciences 77 1194ndash1210

Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

Ursodeoxycholic acid and atorvastin in the treatment of non-alcoholic

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system Ann Clin Lab Sci 30 145-158

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Acta (2011) doi101016jcca201104013

Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

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GLUT4 glucose transporter deficiency increases hepatic lipid production and

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

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genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

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Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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Morris GM Goodsell DS Halliday RS Huey R Hart WE Belew

RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

algorithm and an empirical binding free energy function J Comput Chem

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JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

411

Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

Hall of India Private Ltd New-Delhi 2nd

edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

SA (2004) Inhibition of prostate cancer cell colony formation by the

flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

composition of the fixed and volatile oils of Nigella Sativa L Zeitschrift for

Naturforschung 629-631

Nield and Pearson Burtis CA and Ashwood A (1963) In Text Book of

Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

reperfusion injury Br J Surg 91(2) 184-190

Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

Noguchi N Damiani E Greci L and Niki E (1999) Action of quinolinic

and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

Seeds Food Chem 106 760-766

Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

OConnell OF Ryan L and OBrien NM (2007) Xanthophyll

carotenoids are more bioaccessible from fruits than dark green vegetables

Nutrition Research 27(5) 258minus264

Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

fruits mixtures used in the treatment of diabtes AfrJBiotechnol 7(6) 701-

705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

Portois L and Chardigny JM (2006) Alteration of adipocyte metabolism

in omega3 fatty acid-depleted rats Horm Metab Res 38 789-798

Ohkawa H Ohishi N and Yagi K (1979) Anal Biochem 95 351-358

Okada Y Shibata S Ikekawa T Javellana AMJ and Kamo O (1987)

Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

chlorogenic acid in the leaves and inflorescences of Prunus serotina Ehrh

Acta Chromatographica 19 253-269

Orolowski M and Meister (1963) γ-glutamyl-p-nitroanilide a new

convenient substrate for determination and study of L-and D-glutamyl trans

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Postharvest Biochemistry of Plant Food-Materials in Tropics Japan

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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the hamster The Journal of Clinical Investigation 81 300ndash309

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Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

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Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Higuchi N Kato M and Shundo Y (2008) LiverXreceptor in cooperation

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Hu C and Kitts DD (2005) Dendelion (Taraxacum officinale) flower

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

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and expression of antioxidant genes in hypercholesterolemic rats Free

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Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Jendrassik L and Grof P (1938) Biochem 2297 81

Johnson IT (2004) New approaches to the role of diet in the prevention of

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Jollow DJ and McMillan DC (2001) Oxidative stress glucose-6-

phosphat dehydrogenase and the red cell Adv Exp Med Biol 500 595-605

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streptozotocin diabetes on some urea cycle enzyme Biochem BiophysRes

Commun 106 37-43

Joven J Rull A Ferreacute N Escolagrave-Gil JC Marsillach J Coll B

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Juntachote T and Berghofer E (2005) Antioxidative properties and

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Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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Khan MS Nema N Kharya MD and Khanam S (2009)

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

racemosa extract against chemically induced renal carcinogenesis and

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

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King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Acta (2011) doi101016jcca201104013

Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

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Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

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Korchak HM (1962) Regulation of hepatic lipogenesis Tufts Folia Med

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

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and Food Chemistry 53 1408ndash1416

Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

in patients with nonalcoholic steatohepatitis Journal of Clinical

Gastroenterology 37 177ndash182

Kotani K Peroni OD Minokoshi Y Boss O and Kahn BB (2004)

GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

Koteish A and Diehl AM (2002) Animal models of steatohepatitis Best

Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not

ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

Kowdley KV (2000) Ursodeoxycholic acid therapy in hepatobiliary

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Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

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Kresge N Simoni RD and Hill RL (2006) Forty years of superoxide

dismutase research the work of irwin fridovich [J] J Biol Chem 281(22)

17-19

Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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7 330-338

Kroumltz F Sohn HY and Gloe T (2002) Oxidase-dependent platelet

superoxide anion release incrj5eases platelet recruitment Blood 100 917-

924

Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

mice inhibits neither the CDP-choline pathway for phosphatidylcholine

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23916-23924

Kumar G Sharmila Banu G Kannan V and Rajasekarapandian M

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Kumar V Rani A Dixit A K Pratap D and Bhatnagar D (2010) A

comparative assessment of total phenolic content ferric reducing-anti-

oxidative power free radical-scavenging activity vitamin C and isoflavones

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International 43 323minus328

Kumpulainen JT and Salonen JT (1999) Natural Antioxidants and

Anticarcinogens in Nutrition Health and Disease the Royal Society of

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Kuo YH and Li YC (2000) Four new compounds ficusal

ficusesquilignan A B and ficusolide diacetate from the heartwood of Ficus

microcarpa Chemical and Pharmaceutical Bulletin 48 1862ndash1865

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mayo Clin Proc 55434-438

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Clinical Cancer Research 21 (3) 341ndash346

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

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of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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genotypes under stress of different concentrations of sucrose and sorbito

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

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Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

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Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

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Rheediinosides A and B two antiproliferative and antioxidant triterpene

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Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

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(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

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Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

rich tomato juice and lycopene supplements The FASEB Journal 12(4)

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Rhizobium symbiosis Journal of Experimental Botany 57 (8) 1769-76

Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

Sci 5 445-459

Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

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85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

Ethanopharmacology 91 99-104

Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

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Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Plant Foods for Human Nutrition 63(3) 127minus133

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ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

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Coll Nutr 24 376e384

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

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J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Targher G Bertolini L Padovani R Poli F Scala L Zenari L

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The natural history of nonalcoholic fatty liver a follow-up study

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Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

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Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

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hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

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Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

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induced changes in body mass and hypothalamic gene expression in wild-

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Trivedi CP Shinde S and Sharma RC (1969) Preliminary

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Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

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Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

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Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

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Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

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Van den Berg R Haenen GRMM Van den Berg H and Bast A

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Understanding the human disease The International Journal of Biochemistry

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Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

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protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

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Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

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F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

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liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

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antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

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Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

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effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

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Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

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Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

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Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

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Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

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Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

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Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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ferulic acid a comparative study with other natural oxidation inhibitors

Food Chem 114 466ndash471

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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Jakoby WB and Habig WH (1998) Glutathione transferases In Jakoby

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

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Johnson IT (2004) New approaches to the role of diet in the prevention of

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Commun 106 37-43

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Kantartzis K Peter A Machicao F Machann J Wagner S

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

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Kuo YH and Li YC (2000) Four new compounds ficusal

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Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

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963-968

Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

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Laurin J Lindor KD Crippin JS Gossard A Gores GJ Ludwig J

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

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Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

transplant patients Nutr Rev 60 368-371

Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

biomarkers of inflammation and endothelial dysfunction J Nutr 135 562ndash

566

Louchami K Zhang Y Oguzhan B Delporte C Portois L and

Carpentier YA (2006) Rapid changes in liver lipid composition and

pancreatic islet K+ handling and secretory behaviour provoked by the

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Med 18 1047-1055

Lowry OH Rosebrough NJ Farr AI and Randall RJ (1951) Protein

determination with the folinlsquos phenol reagent JBiolChem 193 265-275

Luck H (1974) In Methods in enzymatic analysisBer Acad N Y 885

Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

steatohepatitis Mayo clinic experiences with a hitherto unnamed disease

Mayo Clin Proc 55434-438

Lugasi A Dworschak E Blazovics A and Kery A (1998) Antioxidant

and free radical scavenging properties of squeezed juice from black radish

(Raphanus sativus I Varniger) root Phytother Res 12 502-506

Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

AA and Khalifa AA (2002) Inhibition of methylnitrosourea (MNU)

induced oxidative stress and carcinogenesis by orally administered bee honey

and Nigella grains in Sprague Dawely rats Journal of Experimental and

Clinical Cancer Research 21 (3) 341ndash346

Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

scavenging potential of Saussarea costua Acta Pharm 55 297-304

Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

cambogia extract on ethanol induced peroxidative damage in rats Indian J

Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

sativa oil against the liver damage induced by Shistosoma mansoni infection

in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

Malik EP Singh MB (1980) Plant Enzymology and Hittoenzymology

1st Edn Kalyani Publishers New Delhi 286

Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

GK (2007) Phytochemical Studies of Strychnos potatorum LF A

Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

A Enrich C Fernandez-Checa JC and Garcia-Ruiz C (2006)

Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

Formosana J Sci Food Agric 88

Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

(2008) Molecular basis and mechanisms of progression of non-alcoholic

steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

Labaudiniere RF (1999) J Med Chem 42 3251e3264

Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

Brief Scientific Literature Review Research Diets Inc 3000-2-09

Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

glutathione transferase activities in the human artery vein and heart J Mol

Cell Cardiol 22 935-938

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Michalak A (2006) Phenolic compounds and their antioxidant activity in

plants growing under heavy metal stress Polish J Environ Studies 15(4)

523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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steatohepatitis Hepatology 37 909ndash16

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Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

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Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

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Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

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Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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Reddy AR Chiatanya KV and vivekanandan M (2004) Draught

induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

Reid AE (2001) Nonalcoholic steatohepatitis Gasteroenterology 121

710-723

Reitman S Frankel S (1957) Amer JClin Path 2856

Rennberg H (1987) Aspects of glutathione function and metabolism in

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York Plenum Press 279-292

Rice EW (1970) Triglycerides in serum In Roderick P MacDc aid CH

(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

Rice-Evans CA Miller NJ and Paganga G (1996) Structurendashantioxidant

activity relationships of flavonoids and phenolic acids J Free Radic Biol

Med 20 933ndash956

Richter C (1987) Biophysical consequences of lipid peroxidation in

membranes Chem Phys Lipids 44(2-4) 175-189

Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

Rizvi MMA Irshad M Hassadi GE and Younis SB (2009) Bio

efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

and Pharmacology 3(6) 287-292

Robak J Gryglewski RJ (1988) Flavonoids are scavengers of superoxide

anions Biochemical Pharmacology 37 837ndash841

Robak J Maran and Kiewicz R (1995) Scavenging of reactive oxygen

species as the mechanism of drug action Polish J of Pharmacol 47 89-98

Robert M (2006) Mineral surfaces and the prebiotic selection and

organization of biomolecules American Mineralogist 91 1715ndash1729

Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

Vaziri ND (2006) Oxidative stress and dysregulation of NAD(P)H oxidase

and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

(5) G1135ndashG1139

Roe J H and Keuther C A (1943) The determination of ascorbic acid in

whole blood and urine through 2 4-dinitro phenyl hydrazine derivative of

dehydro ascorbic acid J Biol Chem 147 399- 407

Rohrdanz E Schmuck G Ohler S and Kahl R (2001) The influence of

oxidative stress on catalase and MnSOD gene transcription in astrocytes

Brain Res 900 128-136

Rojas C Cadenas S Lopez-Torres M Perez-Campo R and Barja G

(1996) Increase in heart glutathione redox and total antioxidant capacity and

dcrease in lipid peroxidation after vitamin E dietary supplementation in

guinea pigs Free Radic Biol Med 21 907-15

Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

MG (2010) Int J Obes (Lond) 34 190ndash194

Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

fermented with Saccharomyces cerevisiae Eur J Lipid Sci Technol 106

424ndash431

Rosen HR and Keefe EB (1998) Laboratory evaluation of the patient

with signs and symptoms of liver disease In clinical practice of

gastroenterology (Brandt LJEd) Churchil Livingstone Philadelphia 812-

820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

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Huang D Ou B and Prior RL (2005) The chemistry behind antioxidant

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1841minus1856

Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes

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Iovin Nicole M Seema Pursnani Voldman A Wasserman G Blaser

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Ismail M Ghanya Al-Naqeep Kim Wei Chan (2010) Nigella sativa

thymoquinone-rich fraction greatly improves plasma antioxidant capacity

and expression of antioxidant genes in hypercholesterolemic rats Free

Radical Biology amp Medicine 48 664ndash672

Itagaki S Kurokawa T Nakata C Saito Y Oikawa S Kobayashi T

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Jain S Dixit Malviya N and Ambawata V (2009) Antioxidant and

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James O and Day C (1999) Non-alcoholic steatohepatitis another disease

of affluence Lancet 353 (9165) 1634ndash1636

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Commun 106 37-43

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Juntachote T and Berghofer E (2005) Antioxidative properties and

stability of ethanolic extracts of Holy basil and Galangal Food Chem 92

193ndash202

Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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Kiyoshi Mizuguchi (2009) Suppression of hepatic fat accumulation by

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diet Biochimica et Biophysica Acta 1791 281ndash288

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

proliferators-activated receptors in the pathogenesis and treatment of

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Kamboj VP (2000) Herbal medicine Curr Med 78 35-39

Kantartzis K Peter A Machicao F Machann J Wagner S

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and Stefan N (2009) Diabetes 58 2616ndash2623

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In O I Aruoma amp B Halliwell (Eds) Free radicals and food additives (pp

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Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

Swrtia chirata on paracetamol and galactosamine induced hepatotoxicity in

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

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Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Kaufmann (1999) National products of high pharmacological potency

Biochem pharmacol 32 1141-1148

Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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Khan MS Nema N Kharya MD and Khanam S (2009)

Chromatographic estimation of maturity based phytochemical profiling of

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

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Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

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Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

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Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

A Enrich C Fernandez-Checa JC and Garcia-Ruiz C (2006)

Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

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Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

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Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

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McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Mervat MM and Taie HAA (2009) Antioxidant activities total

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

glutathione transferase activities in the human artery vein and heart J Mol

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plants growing under heavy metal stress Polish J Environ Studies 15(4)

523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

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syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

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syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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glucose amine Japanese Journal of Nutrition 44307-315

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Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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action Diabetologia 47170ndash84

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Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

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abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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decolorisation assay Free Radical Biol Med 26 1231-1237

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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(5) G1135ndashG1139

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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development of non-alcoholic steatohepatitis in a dietary murine model Am

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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Sasaki YF Kawaguchi S KamayaA OhshitaM Kabasawa K and

Iwama K (2002) The comet assay with 8 mouse organs Results with 39

currently used food additives Mutation ResearchGenetic Toxicology and

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Satyavati GV (1982) Some traditional medical systems and practise of

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Sauberlich HE (1999) Laboratory tests for the assessment of nutritional

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Ed CRC press Boca RatonFL

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Westernized-likediet-fed rats effect on glucose homeostasis lipid profile

and adipocyte hormones and their modulation by rosiglitazone and

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Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Seth and Bhawana Sharma (2004) Medicinal plants in India Commentary

Indian J Med Res 120 9-11

Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

muscle) Therapie 46 351ndash354

Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

antioxidant studies of Ficus Racemosa Linnroot 13 (4) 70-74

Sharma P and Dubey RSH (2005) Drought induces stress and enhances

the activities of antioxidant enzymes in growing rice seedlings Plant Growth

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Shenoy KA Somayaji SN and Bairy KL (2001) Hepatoprotective

effects of Ginkgo biloba against CCl4 induced hepatic injury in rats Ind J

Pharamacol 33 260-266

Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

Y and Yoshimura K (2002) ―Regulation and function of ascorbate

peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

Shimada K Fujikawa K Yahara K and Nakamura T (1992)

Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

SREBP family FEBS J 276616ndash621

Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

Sies H (1997) Oxidative stress oxidants and antioxidants Exp Physiol

82 291-295

Sies H and Cadenas E (1985) Oxidative stress damage to intact cells and

organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

hydroxynonenal by JNKc-Jun overactivation Am J Physiol Gastrointest

Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

(2010) Antioxidant Properties of Ficus Species ndash A Review International

Journal of PharmTech Research CODEN (USA) IJPRIF ISSN 0974-

4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

Sivarajan VV and Balachandran I (1994) Ayurvedic Drugs and their

Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

Smid E J De Witte Y and Gorris L G M (1995) Postharvest Biol

Technol 6 303

Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

266

Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

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Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

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Juurlink BH and Paterson PG (1998) Review of oxidative stress in brain

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Kallwitz ER McLachlan A and Cotler SJ (2008) Role of peroxisome

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Kantartzis K Peter A Machicao F Machann J Wagner S

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Karan M Vasisht K and Handa SS (1999) Antihepatotoxic activity of

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Karu N Reifen R and Kerem Z (2007) Weight gain reduction in mice

fed Panax ginseng saponin a pancreatic lipase inhibitor J Agric Food Chem

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Kataria M and Singh LN (1997) Hepatoprotective effect of Liv-52 and

Kumaryasava on CCl4 induced hepatic damage in rats Indian Journal of

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Katz D Mazor D Dvilansky A and Meyerstein N (1996) Effect of

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Kaufmann (1999) National products of high pharmacological potency

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Kechagias S Ernersson A Dahlqvist O Lundberg P Lindstrom T and

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Keeling CI and Bohlmann J (2006) Genes enzymes and chemicals of

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against insects and pathogens New Phytol 170 657-675

Kefalas P Kallithraka S Parejo I and Makris DP (2003) Food Sci

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Kelloff GJ Boone CW Crowell JA Steele VE Lubet RA Doody

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Khan MS Nema N Kharya MD and Khanam S (2009)

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

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Kim YS Bahn KN Hah CK Gang HI and Ha YL (2008)

Inhibition of 712-dimethylbenz[a]anthracene induced mouse skin

carcinogenesis by Artemisia capillaries J Food Sci 73 T16ndash20

Kim YY Kang HJ Ko SK and Chung SH (2002) Sopungsungiwon

(SP) prevents the onset of hyperglycemia and hyperlipidemia in Zucker

diabetic fatty rats Archives Pharmacal Research 25 923ndash931

King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kinnunen PK (1991) On the principles of functional ordering in biological

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Kitchen DB Decornez H Furr JR and Bajorath J (2004) Docking and

scoring in virtual screening for drug discovery methods and applications

Nature reviews Drug discovery 3(11) 935ndash49 doi101038nrd1549

PMID 15520816

Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

Ursodeoxycholic acid and atorvastin in the treatment of non-alcoholic

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Klichko VI Radyuk SN and Orr WC (2004) Profiling catalase gene

expression in Drosophilla melanogastr during development and aging

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Knight JA (2000) Review Free radicals antioxidants and the immune

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Knowles JR (1989) The mechanism of biotin-dependent enzymes Ann

Rev Biochem 58 195ndash221

Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

al The role of oxidative stress in non-alcoholic steatohepatitis Clin Chim

Acta (2011) doi101016jcca201104013

Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

antioxidant activity of silymarin Journal of Enzyme Inhibition and

Medicinal Chemistry 24(2) 395minus405

Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

and Dosso M (2004) Traditional medicine in North Cocircte-DlsquoIvoire

Screening of 50 medicinal plants for antibacterial activity Journal of

Ethnopharmacology 93 43ndash49

Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

feeding results in higher serum alanine aminotransferase and increased

insulin resistance compared with a standard murine high-fat diet Am J

Physiol Gastrointest Liver Physiol 297 G378ndashG384

Korchak HM (1962) Regulation of hepatic lipogenesis Tufts Folia Med

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Kordali S Cakir A Mavi A Kilic H and Yildirim A (2005) Screening

of chemical composition and antifungal and antioxidant activities of the

essential oils from three Turkish Artemisia species Journal of Agricultural

and Food Chemistry 53 1408ndash1416

Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

in patients with nonalcoholic steatohepatitis Journal of Clinical

Gastroenterology 37 177ndash182

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GLUT4 glucose transporter deficiency increases hepatic lipid production and

peripheral lipid utilization J Clin Invest 114 1666ndash1675

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Kotronen A Seppanen-Laakso T and Westerbacka J (2009) Hepatic

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ceramide concentrations are increased in the nonalcoholic human fatty liver

Diabetes 58(1) 203ndash8

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17-19

Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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924

Kulinski A Vance DE and Vance JE (2004) A choline-deficient diet in

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comparative assessment of total phenolic content ferric reducing-anti-

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Anticarcinogens in Nutrition Health and Disease the Royal Society of

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

and Newmana B (2008) Ficus spp (fig) Ethnobotany and potential as

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23 1464ndash1467

Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

lipid-lowering and insulin-sensitizing actions in the rat Journal of

Ethnopharmacology 94 251ndash259

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

extracts for antioxidant activity Life Sci 73 167-179

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Leung KK and Leung PS (2008) Effects of hyperglycemia on

angiotensin receptor type 1 expression and insulin secretion in an INS-1E

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Food Chemistry 53(1) 103minus110

Lieber CS (1997) Cytochrome P-4502E1 its physiological and

pathological role Physiol Rev 77 517ndash 44

Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

transplant patients Nutr Rev 60 368-371

Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

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Mayo Clin Proc 55434-438

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

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genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

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relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

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preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

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Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

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edn 59-61

Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

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Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

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Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

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Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

Noguchi N Damiani E Greci L and Niki E (1999) Action of quinolinic

and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

Seeds Food Chem 106 760-766

Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

OConnell OF Ryan L and OBrien NM (2007) Xanthophyll

carotenoids are more bioaccessible from fruits than dark green vegetables

Nutrition Research 27(5) 258minus264

Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

fruits mixtures used in the treatment of diabtes AfrJBiotechnol 7(6) 701-

705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

Portois L and Chardigny JM (2006) Alteration of adipocyte metabolism

in omega3 fatty acid-depleted rats Horm Metab Res 38 789-798

Ohkawa H Ohishi N and Yagi K (1979) Anal Biochem 95 351-358

Okada Y Shibata S Ikekawa T Javellana AMJ and Kamo O (1987)

Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

chlorogenic acid in the leaves and inflorescences of Prunus serotina Ehrh

Acta Chromatographica 19 253-269

Orolowski M and Meister (1963) γ-glutamyl-p-nitroanilide a new

convenient substrate for determination and study of L-and D-glutamyl trans

peptidase activities Biochemica Biophysica Acta 73 679-681

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Postharvest Biochemistry of Plant Food-Materials in Tropics Japan

Scientific Society Press Tokyo 241-251

Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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A544minusA

Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

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and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Med Hypotheses 60 567-572

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

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pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

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human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

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Rev Mol Cell Biol 9 162ndash176

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

Page 24: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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Katina K Arendt E Liukkonen KH Autio K Flander L and Poutanen

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Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

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Kraegen EW Clark PW Jenkins AB Daley EA Chisholm DJ and

Storlien LH (1991) Development of muscle insulin resistance after liver insulin

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Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

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Latha M and Pari L (2004) Effect of an aqueous extract of Scoparia dulcis

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

and Haddad P (2004) The petroleum ether extract of Nigella sativa exerts

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Ethnopharmacology 94 251ndash259

Leclercq I Field J Erriquez A Farrell GC (2007) Robertson G

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

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Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

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527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

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Malik EP Singh MB (1980) Plant Enzymology and Hittoenzymology

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

(2008) Molecular basis and mechanisms of progression of non-alcoholic

steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

Brief Scientific Literature Review Research Diets Inc 3000-2-09

Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

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morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

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investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

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anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

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patients Nutr Rev 58 278-281

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biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

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and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

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radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

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syndrome) and obesity in Asian Indians Evidence and implications

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Reitman S Frankel S (1957) Amer JClin Path 2856

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Richter C (1987) Biophysical consequences of lipid peroxidation in

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Robak J Gryglewski RJ (1988) Flavonoids are scavengers of superoxide

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organization of biomolecules American Mineralogist 91 1715ndash1729

Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

Vaziri ND (2006) Oxidative stress and dysregulation of NAD(P)H oxidase

and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

(5) G1135ndashG1139

Roe J H and Keuther C A (1943) The determination of ascorbic acid in

whole blood and urine through 2 4-dinitro phenyl hydrazine derivative of

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Rohrdanz E Schmuck G Ohler S and Kahl R (2001) The influence of

oxidative stress on catalase and MnSOD gene transcription in astrocytes

Brain Res 900 128-136

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(1996) Increase in heart glutathione redox and total antioxidant capacity and

dcrease in lipid peroxidation after vitamin E dietary supplementation in

guinea pigs Free Radic Biol Med 21 907-15

Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

MG (2010) Int J Obes (Lond) 34 190ndash194

Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

fermented with Saccharomyces cerevisiae Eur J Lipid Sci Technol 106

424ndash431

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with signs and symptoms of liver disease In clinical practice of

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

Roy S Sehgal R Pahdy BM and Kumar VL (2005) Antioxidant and

protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

(2008) Micellarisation of carotenoids from raw and cooked vegetables

Plant Foods for Human Nutrition 63(3) 127minus133

Sadasivam S Manickam A (1997) Biochemical methods Second edition

Newage international Pvt Ltd

Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

(2004) Up regulation of osteopontin expression is involved in the

development of non-alcoholic steatohepatitis in a dietary murine model Am

J Physiol Gastrointest Liver Physiol 287 G264-G273

Sahreen S Rashid Khan M and Ali Khan R (2010) Evaluation of

antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

RK (2002) Antiulcerogenic activity of methanolic extract of Emblica

Officinalis Journal of Ethanopharmacology 82 1-9

Sallie R Tredgr JM and William (1999) Drugs and the liver Biopharm

Drug Dispos 12 251-259

Salom S M Gray J A Alford A R Mulesky M Fettig C J and

Woods S A (1996) J Entomol Sci 31 453

Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

AJ and Shulman GI (2004) Mechanism of hepatic insulin resistance in

non-alcoholic fatty liver disease J Biol Chem 279 32345-32353

Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

Sarabu R and Tilley J (2005) Annu Rep Med Chem 40 167e181

Elsevier Academic Press

Sasaki YF Kawaguchi S KamayaA OhshitaM Kabasawa K and

Iwama K (2002) The comet assay with 8 mouse organs Results with 39

currently used food additives Mutation ResearchGenetic Toxicology and

Environmental Mutagenesis 519 103ndash109

Satheesh AM and Pari L (2004) Antioxidant effect of Boerhavia diffusa

L in tissues of alloxan induced diabetic rats Indian J Exp Biol 42 989-

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Satyavati GV (1982) Some traditional medical systems and practise of

global importance Indian J Med Res 76 1

Sauberlich HE (1999) Laboratory tests for the assessment of nutritional

status 2nd

Ed CRC press Boca RatonFL

Scandalios JG (1987) The antioxidant enzyme genes CAT and SOD of

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Khan N and Sultana ST (2005) Chemomodulatory effect of Ficus

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King J (1965a) The hydrolases-acid and alkaline phosphatise In Practical

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King J (1965b) The dehydrogenase or oxidoreductase-Lactate

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Kiyici M Gulten M Gurel S Nak SG Dolar E and Savci G (2003)

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Koek GH et al Clinica Chimica Acta xxx (2011) xxxndashxxx Koek GH et

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Koumlksal E Guumllccedilin İ Ozturk Sarıkaya S B and Bursal E (2009) In vitro

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Kondo K Hirano R Matsumoto A Igarashi O and Itakura H (1996)

Inhibition of LDL oxidation by cocoa Lancet 348 1514

Koneacute WM Atindehou KK Terreaux C Hostettmann K Traoreacute D

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Screening of 50 medicinal plants for antibacterial activity Journal of

Ethnopharmacology 93 43ndash49

Koppe SW Elias M Moseley RH and Green RM (2009) Trans fat

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Koruk M Savascedil MC Yilmaz O Tayscedil iS Karakok M Guumlndolsquogdu C

and Yilmaz A (2003) Serum lipids lipoproteins and apolipoproteins levels

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GLUT4 glucose transporter deficiency increases hepatic lipid production and

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Le K Chiu F and Ng K (2007) Identification and quantification of

antioxidants in Fructus lycii Food Chemistry 105 353ndash363

Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Ethnopharmacology 94 251ndash259

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Dietary carvacrol lowers body weight gain but improves feed conversion in

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Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

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Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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supplementation retards early progression of arteriosclerosis in heart

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

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metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

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Progress in Lipid Research 48 1e26

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relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

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preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

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Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

Human Biology Talwar GP Srivastava LM and Moudgil K D Prentice-

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Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

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flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

model of non-alcoholic steatohepatitis J Clin Biochem Nutr 44 239ndash46

Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

Nutrition 79(3) 350ndash351

Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

composition of the fixed and volatile oils of Nigella Sativa L Zeitschrift for

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Clinical Chemistry Chap27 Oxford Press New York 1280-1282

Ninomiya M Shimada M and Harada N (2004) The hydroxyl radical

scavenger MCI-186 protects the liver from experimental cold ischaemia-

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Noctor G and Foyer CH (1998) Ascorbate and Glutathione Keeping

active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

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and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

Seeds Food Chem 106 760-766

Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

OConnell OF Ryan L and OBrien NM (2007) Xanthophyll

carotenoids are more bioaccessible from fruits than dark green vegetables

Nutrition Research 27(5) 258minus264

Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

Portois L and Chardigny JM (2006) Alteration of adipocyte metabolism

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Okada Y Shibata S Ikekawa T Javellana AMJ and Kamo O (1987)

Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

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Acta Chromatographica 19 253-269

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

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Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

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85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

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Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Med Hypotheses 60 567-572

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

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Toxicology 48 704ndash709

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Am J Gastroenterol 99 1497ndash1502

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Page 26: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

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Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

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Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

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Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

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Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

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Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

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Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

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Mayes AP (1993) Structure and function of the lipid soluble vitamins In

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

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syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

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syndrome) and obesity in Asian Indians Evidence and implications

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

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diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Rahman NN Khan M and Hasan R (1994) Bioactive components from

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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decolorisation assay Free Radical Biol Med 26 1231-1237

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Reitman S Frankel S (1957) Amer JClin Path 2856

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

Rice-Evans CA Miller NJ and Paganga G (1996) Structurendashantioxidant

activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Richter C (1987) Biophysical consequences of lipid peroxidation in

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

(5) G1135ndashG1139

Roe J H and Keuther C A (1943) The determination of ascorbic acid in

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Rohrdanz E Schmuck G Ohler S and Kahl R (2001) The influence of

oxidative stress on catalase and MnSOD gene transcription in astrocytes

Brain Res 900 128-136

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dcrease in lipid peroxidation after vitamin E dietary supplementation in

guinea pigs Free Radic Biol Med 21 907-15

Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

fermented with Saccharomyces cerevisiae Eur J Lipid Sci Technol 106

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

Roy S Sehgal R Pahdy BM and Kumar VL (2005) Antioxidant and

protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

(2008) Micellarisation of carotenoids from raw and cooked vegetables

Plant Foods for Human Nutrition 63(3) 127minus133

Sadasivam S Manickam A (1997) Biochemical methods Second edition

Newage international Pvt Ltd

Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

(2004) Up regulation of osteopontin expression is involved in the

development of non-alcoholic steatohepatitis in a dietary murine model Am

J Physiol Gastrointest Liver Physiol 287 G264-G273

Sahreen S Rashid Khan M and Ali Khan R (2010) Evaluation of

antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

RK (2002) Antiulcerogenic activity of methanolic extract of Emblica

Officinalis Journal of Ethanopharmacology 82 1-9

Sallie R Tredgr JM and William (1999) Drugs and the liver Biopharm

Drug Dispos 12 251-259

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Woods S A (1996) J Entomol Sci 31 453

Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

AJ and Shulman GI (2004) Mechanism of hepatic insulin resistance in

non-alcoholic fatty liver disease J Biol Chem 279 32345-32353

Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

Sarabu R and Tilley J (2005) Annu Rep Med Chem 40 167e181

Elsevier Academic Press

Sasaki YF Kawaguchi S KamayaA OhshitaM Kabasawa K and

Iwama K (2002) The comet assay with 8 mouse organs Results with 39

currently used food additives Mutation ResearchGenetic Toxicology and

Environmental Mutagenesis 519 103ndash109

Satheesh AM and Pari L (2004) Antioxidant effect of Boerhavia diffusa

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Satyavati GV (1982) Some traditional medical systems and practise of

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Sauberlich HE (1999) Laboratory tests for the assessment of nutritional

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Ed CRC press Boca RatonFL

Scandalios JG (1987) The antioxidant enzyme genes CAT and SOD of

maize regulation functional significance and molecular biology

Isoenzymes Curr Top Biol Med Res 14 19-44

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Westernized-likediet-fed rats effect on glucose homeostasis lipid profile

and adipocyte hormones and their modulation by rosiglitazone and

glimepiride J Diabetes Complications 23199ndash208

Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

resistance Proc Nutr Soc 66 33ndash41

Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Seth and Bhawana Sharma (2004) Medicinal plants in India Commentary

Indian J Med Res 120 9-11

Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

muscle) Therapie 46 351ndash354

Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

antioxidant studies of Ficus Racemosa Linnroot 13 (4) 70-74

Sharma P and Dubey RSH (2005) Drought induces stress and enhances

the activities of antioxidant enzymes in growing rice seedlings Plant Growth

hybrid mean were Regul 46 209-221

Shenoy KA Somayaji SN and Bairy KL (2001) Hepatoprotective

effects of Ginkgo biloba against CCl4 induced hepatic injury in rats Ind J

Pharamacol 33 260-266

Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

Y and Yoshimura K (2002) ―Regulation and function of ascorbate

peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

Shimada K Fujikawa K Yahara K and Nakamura T (1992)

Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

SREBP family FEBS J 276616ndash621

Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

Sies H (1997) Oxidative stress oxidants and antioxidants Exp Physiol

82 291-295

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organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Krishnamoorthy V Divianathan S Subramanian B and Shanmugam M

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Kurian GA and Paddikkala J (2009) Administration of aqueous extract of

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Lansky EP Helena M Paavilainena Alison D Pawlus B Robert A

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Lapenna D Del Boccio G Porreca E Pennelli A Mezzetti A De

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Latha M and Pari L (2004) Effect of an aqueous extract of Scoparia dulcis

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Le K Chiu F and Ng K (2007) Identification and quantification of

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Leclercq I Field J Erriquez A Farrell GC (2007) Robertson G

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

Polyunsaturated fat in the methionine-choline-deficient diet influences

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Lee JK N and Min DB (2004) Reactive Oxygen Species Aging and

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33

Lee KS Buck M Houglum K and Chojkier M (1995) Activation of

hepatic stellate cells by TGF alpha and collagen type I is mediated by

oxidative stress through c-myb expression J Clin Invest 96 2461ndash2468

Lee KW Everts H Kappert HJ Yeom KH and Beynen AC (2003)

Dietary carvacrol lowers body weight gain but improves feed conversion in

female broiler chickens Journal of Applied Poultry Research 12 394ndash399

Lee SE Hwang HJ and HA JS (2003) Screening of medicinal plant

extracts for antioxidant activity Life Sci 73 167-179

Leeuenberg C and Ji LL (1995) Glutathione depletion in rested and

exercised mice Biochemical consequence and adaption Arch Biochem

Niophys 316 941-949

Lenhard JM (2007) Gottschalk WK (2002) Preclinical developmentsin

type 2 diabetes Advanced Drug Delivery Reviews 54 1199ndash1212

Leung KK and Leung PS (2008) Effects of hyperglycemia on

angiotensin receptor type 1 expression and insulin secretion in an INS-1E

pancreatic beta-cell line JOP 9 290ndash299

Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect

on hyperlipidemic mice Phytotherapy Research 22 159ndash164

Lichtenthaler R and Marx F (2005) Total oxidant scavenging capacities of

common European fruit and vegetable juices Journal of Agricultural and

Food Chemistry 53(1) 103minus110

Lieber CS (1997) Cytochrome P-4502E1 its physiological and

pathological role Physiol Rev 77 517ndash 44

Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β

coactivation of SREBP Cell 120261ndash73

Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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cirrhosis Gastroenterology 106 1284ndash1290

Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

Angulo P (2004) Ursodeoxycholic for treatment of non-alcoholic steatohepatitis

results of a randomized trial Hepatology 39 770-8

Liochev SI and Fridovich I (1994) The role of O2 in the production of

HO in vitro and in vivo Free Radical Biology and Medicine 16 29ndash36

Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

supplementation retards early progression of arteriosclerosis in heart

transplant patients Nutr Rev 60 368-371

Lizardi-Cervera J and Aquilar-Zapata D (2009) Nonalcoholic fatty liver

disease and its association with cardiovascular disease 8 S40ndashS43

Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

biomarkers of inflammation and endothelial dysfunction J Nutr 135 562ndash

566

Louchami K Zhang Y Oguzhan B Delporte C Portois L and

Carpentier YA (2006) Rapid changes in liver lipid composition and

pancreatic islet K+ handling and secretory behaviour provoked by the

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Lowry OH Rosebrough NJ Farr AI and Randall RJ (1951) Protein

determination with the folinlsquos phenol reagent JBiolChem 193 265-275

Luck H (1974) In Methods in enzymatic analysisBer Acad N Y 885

Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

steatohepatitis Mayo clinic experiences with a hitherto unnamed disease

Mayo Clin Proc 55434-438

Lugasi A Dworschak E Blazovics A and Kery A (1998) Antioxidant

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(Raphanus sativus I Varniger) root Phytother Res 12 502-506

Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

AA and Khalifa AA (2002) Inhibition of methylnitrosourea (MNU)

induced oxidative stress and carcinogenesis by orally administered bee honey

and Nigella grains in Sprague Dawely rats Journal of Experimental and

Clinical Cancer Research 21 (3) 341ndash346

Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

scavenging potential of Saussarea costua Acta Pharm 55 297-304

Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

cambogia extract on ethanol induced peroxidative damage in rats Indian J

Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

sativa oil against the liver damage induced by Shistosoma mansoni infection

in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

Malik EP Singh MB (1980) Plant Enzymology and Hittoenzymology

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

GK (2007) Phytochemical Studies of Strychnos potatorum LF A

Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

Formosana J Sci Food Agric 88

Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

(2008) Molecular basis and mechanisms of progression of non-alcoholic

steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

Labaudiniere RF (1999) J Med Chem 42 3251e3264

Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

obesity Obes Res 3 187Sndash194S

Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

severity Gastroenterology 116 1413e1419

Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

Rev 21 585e618

Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

Brief Scientific Literature Review Research Diets Inc 3000-2-09

Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

Mayes AP (1993) Structure and function of the lipid soluble vitamins In

Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

Biochemistry Chap 53 Prentice-Hall International Inc 23rd

edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

Atherosclerosis 145 421ndash422

McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

investigation of fruits of Ficus glomerata Roxb Indian J Chem 17B 87ndash88

Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

glutathione transferase activities in the human artery vein and heart J Mol

Cell Cardiol 22 935-938

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523-530

Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

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Indian Phenotype J Assoc Physic Ind 54 685-6

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risk factor study Br J Nutr 100 (4) 890ndash895

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

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Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

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Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

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steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

and Function 19 125ndash132

Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

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Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

Pirola L Johnston AM Van Obberghen E (2004) Modulation of insulin

action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

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Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

Prasamthi Muralidhara K and Rajini PS (2005) Fenvalerate-induced

oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

Pryor WA (1993) Measurement of oxidative stress status in humans

Cancer Epidemiol Biomarkers Prev 2 289-292

Puppo A (1992) Effect of flavonoids on hydroxyl radical formation by

Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

Rachna A and Abdelhaq R (2003) Redistribution of glucose-6-phosphate

dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

Rahman NN Khan M and Hasan R (1994) Bioactive components from

Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

Rajesh MG and Latha MS (2004) Preliminary evaluation of the

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

Ramadan MF (2007) Nutritional value functional properties and

nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

Recknagel RO Glende EA JR Waller RL and Loery K (1982) Lipid

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Reddy AR Chiatanya KV and vivekanandan M (2004) Draught

induced response of photosynthesis and antioxidant metabolism in higher

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

Reid AE (2001) Nonalcoholic steatohepatitis Gasteroenterology 121

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Reitman S Frankel S (1957) Amer JClin Path 2856

Rennberg H (1987) Aspects of glutathione function and metabolism in

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York Plenum Press 279-292

Rice EW (1970) Triglycerides in serum In Roderick P MacDc aid CH

(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Nonalcoholic steatohepatitis association of insulin resistance and

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Wang X and Quinn P (1999) Vitamin E and its function in membranes

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Lipidol 19 92ndash4

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PMID 15046985

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Preparation and Pharmacological evaluation of plant material England John

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Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

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reducing antioxidant power assay Food Chem 97 705-711

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World Health Organisation (2006) Obesity and overweight Fact sheet 311

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Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

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mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

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dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

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Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

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You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

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Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

Page 28: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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Le PM Benhaddou-Andaloussi A Elimadi A Settaf A Cherrah Y

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Leclercq IA (2007) Pathogenesis of steatohepatitis insights from the study

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Lee GS Yan JS Ng RK Kakar S and Maher JJ (2007)

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Li H Wang QJ Zhu DN and Yang Y (2008) Reinioside C a

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on hyperlipidemic mice Phytotherapy Research 22 159ndash164

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Food Chemistry 53(1) 103minus110

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

Ponomarenko A and DeCarli LM (2004) Model of nonalcoholic

steatohepatitis The American Journal of Clinical Nutrition 79(3) 502ndash509

Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Dickson ER Baldus WP Jorgensen RA Ludwig J

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

Angulo P (2004) Ursodeoxycholic for treatment of non-alcoholic steatohepatitis

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HO in vitro and in vivo Free Radical Biology and Medicine 16 29ndash36

Lippincott Williams and Wilkins Instructorlsquos Resource Parthlsquos

Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

accumulation in lives of rats fed a cholesterol-supplemented diet Lipids 30

527ndash531

Liu F and Ng TB (2000) Antioxidative and free radical scavenging

activities of selected medicinal herbs Life Sciences 66 725ndash735

Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

activity of mushroom polysaccharide extracts Life Science 60 763-771

Liu L and Meydani M (2002) Combined vitamin C and E

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

identify unknown compounds in herbal extracts 1-4

Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

sativa oil against the liver damage induced by Shistosoma mansoni infection

in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Medicinal Plant 4(4) 510-518

Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

acids on insulin sensitivity and secretion Diabetes Obesity and Metabolism

6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

(2000) J Natl Cancer Inst 92 154

Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

A Enrich C Fernandez-Checa JC and Garcia-Ruiz C (2006)

Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

activity of the ethanolic extract from the bark of Chamaecyparis obtuse var

Formosana J Sci Food Agric 88

Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

Atheroscler Rep 6 73-78

Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

595-603

Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

mice fed an atherogenic diet Hepatology 46 1392ndash1403

Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

Nonalcoholic fatty liver disease a spectrum of clinical and pathological

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

morbid obesity Hepatology 3 226ndash231

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

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McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

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vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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genotypes under stress of different concentrations of sucrose and sorbito

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

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biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

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metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

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risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

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Progress in Lipid Research 48 1e26

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steatohepatitis Hepatology 37 909ndash16

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Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

Ogino T (2009) Beneficial effects of fermented green tea extract in a rat

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Nanji AA (2004b) Another animal model for nonalcoholic steatohepatitis

how close to the human condition The American Journal of Clinical

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Nanji AA (2004a) Animal models of nonalcoholic fatty liver disease and

steatohepatitis Clinics in Liver Disease 8 (3) 559ndash574 (ix)

Neuhouser ML (2004) Flavonoids and cancer risk evidence from human

population studies Nutr Cancer 50 1-7

Neuschwander-Tetri BA and Caldwell SH (2003) Nonalcoholic

steatohepatitis summary of an AASLD single topic conference Hepatology

371202ndash19

Newman DJ Cragg GM and Snader KM (2000) The influence of

natural products upon drug discovery Nat Prod Rep 17 175-285

Nickavar B Mojab F Javidnia K and Amoli M AR (2003) Chemical

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Clinical Chemistry Chap27 Oxford Press New York 1280-1282

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active oxygen under control Annual Review of Plant Physiology and Plant

Molecular Biology 49 249-279

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and indolinonic aminoxyls as radical-scavenging antioxidants Chem Phys

Lipids 99 11-19

Nsimba R Kikuzaki H and Konishi Y (2008) Antioxidant activity of

various extracts and fractions of Chenopodium quinoa and Amaranthus spp

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Nzowa LK Barboni L Teponno RB Ricciutelli M Lupidi G Luana

Quassinti L Massimo Bramucci M and Tapondjou LA (2010)

Rheediinosides A and B two antiproliferative and antioxidant triterpene

saponins from Entada rheedii Phytochemistry 71 254ndash261

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carotenoids are more bioaccessible from fruits than dark green vegetables

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Ogbonnia OS Nkemehule EF and Anyika NE (2009) Evaluation of

acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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705

Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Okada Y Shibata S Ikekawa T Javellana AMJ and Kamo O (1987)

Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

Olszewska M (2007) Quantitative HPLC analysis of flavonoids and

chlorogenic acid in the leaves and inflorescences of Prunus serotina Ehrh

Acta Chromatographica 19 253-269

Orolowski M and Meister (1963) γ-glutamyl-p-nitroanilide a new

convenient substrate for determination and study of L-and D-glutamyl trans

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Postharvest Biochemistry of Plant Food-Materials in Tropics Japan

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

Oyaizu M (1986) Studies on product of browning reaction prepared from

glucose amine Japanese Journal of Nutrition 44307-315

Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

33 439ndash447

Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

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(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Med Hypotheses 60 567-572

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

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Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

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Toxicology 48 704ndash709

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Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

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Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

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Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

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Lieber CS Leo MA Mak KM Xu Y Cao Q Ren C

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Lin J Yang R Tarr PT Wu PH Handschin C and Li S (2005)

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Lindor KD Kodley KV Heathcote EJ Harrison ME Jorgensen R and

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Pathophysiology Concepts of Altered Health States Seventh edition 2008

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Avila V L and A and Yefchak G (2009) Use of GC-QTOF MS to

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Ludwig J Viggiano TR McGill DB and Ott BJ (1980) Non-alcoholic

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

inflammation and atherogenesis Endocrinology 144 2195ndash2200

Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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in mice Journal of Ethnopharmacology 79 1ndash11

Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

ursodeoxycholic acid Nippon Shokakibyo Gakkai Zasshi 72 690ndash702

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

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Manian R Anusuya N Siddhuraju P and Manian S (2008) The

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solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

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Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

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Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

disease predisposing factors and the role of nutrition Journal of Nutritional

Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

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edition 588-

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Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

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vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

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Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

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Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

Mucuna pruriens Linn And formation containing Mpruriens by HPTLC

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

India 52468ndash474

Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

Indian Phenotype J Assoc Physic Ind 54 685-6

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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RK and Olson AJ (1998) Automated docking using a Lamarkian genetic

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Moss DW and Butterorth PJ (1974) Enzymology and Medicine London

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Mursu J Voutilainen S Nurmi T Tuomainen TP Kurl S and Salonen

JT (2008) Flavonoid intake and the risk of ischaemic stroke and CVD

mortality in middle aged Finnishmen The Kuopio Ischaemic heart disease

risk factor study Br J Nutr 100 (4) 890ndash895

Musso G Gambino R and Cassader M (2009) Recent insights into

hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Progress in Lipid Research 48 1e26

Musso G Gambino R and De Michieli F (2003) Dietary habits and their

relations to insulin resistance and postprandial lipemia in nonalcoholic

steatohepatitis Hepatology 37 909ndash16

Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

subacute toxicity studies with Kalpaamruthaa a modified indigenous

preparation on rats J Health Sci 53(4) 351-358

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(Ed) Indian Materia Medica Popular Prakashan Bombay India pp 386ndash

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Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

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Nair HK Rao KV Aalinkeel R Mahajan S Chawda R and Schwartz

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flavonoid quercetin correlates with modulation of specific regulatory genes

Clin Diagn Lab Immunol 11 63-69

Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Lipids 99 11-19

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carotenoids are more bioaccessible from fruits than dark green vegetables

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acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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convenient substrate for determination and study of L-and D-glutamyl trans

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(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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diabetes Science 306457ndash61

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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(2009b) The beneficial effects of morroniside on the inflammatory response

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289e298

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

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with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

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Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Hepatology 22 1714ndash1719

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activation of AMP-dependent protein kinase Food and Chemical

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

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Pathophysiology Concepts of Altered Health States Seventh edition 2008

Liu C H Hung M T and Huang P C (1995) Source of triacylglycerol

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Liu F and Ng TB (2000) Antioxidative and free radical scavenging

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Liu F Ooi VEC and Chang S T (1997) Free radical scavenging

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Lopez-Garcia E Schulze MB Meigs JB Manson JE Rifai N and

Stampfer MJ (2005) l Consumption of trans fatty acids is related to plasma

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Louchami K Zhang Y Oguzhan B Delporte C Portois L and

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Lyon CJ Law RE and Hsueh WA (2003) Minireview adiposity

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Mabrouk GM Moselhy SS Zohny SF Ali EM Helal TE Amin

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Madan MP Raghavan G Singh AK and Palpu P (2005) Free radical

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Mahendran P and Devi CSS (2001) The modulating effect of Garicinia

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Pharmacology 33 87-91

Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

Dissolution of cholesterol gallstones by long-term administration of

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Mallikharjuna PB Rajanna LN Seetharam YN and Sharanabasappa

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

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6 402ndash413

Manian R Anusuya N Siddhuraju P and Manian S (2008) The

antioxidant activity and free radical scavenging potential of two different

solvent extracts of Camellia sinensis (L) O Kuntz Ficus bengalensis L and

Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

R Natale S Vanni E Villanova N Melchionda N and Rizzetto M

(2003) Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome

Hepatology 37 917ndash 923

Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Mitochondrial free cholesterol loading sensitizes to TNF and Fas-meidated

steatohepatitis Cell Metabolism 4 185ndash198

Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

activity and phenolic content of phenolic rich fractions obtained from black

cumin (Nigella sativa) seedcake Food Chemistry 116 306ndash312

Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

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Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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steatohepatitis Trends Mol Med 14 72ndash81

Mason JS Morize I Menard PR Cheney DL Hulme C and

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

Tokunaga K (1995) Pathophysiology and pathogenesis of visceral fat

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

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Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

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Mayes AP (1993) Structure and function of the lipid soluble vitamins In

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

ascorbate Ann Rev Nutr 5 323-340

McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

5896minus5904

Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

(2008) Med Chem Res 17 462ndash473

Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

(4) 505ndash524 doi101002jcc540130412

Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Cell Cardiol 22 935-938

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Michalak A (2006) Phenolic compounds and their antioxidant activity in

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

formulation in galactosamine induced hepatopathy in rats Indian J Physiol

Pharmacol 44 82-86

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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development of non-alcoholic steatohepatitis in a dietary murine model Am

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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and adipocyte hormones and their modulation by rosiglitazone and

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Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

muscle) Therapie 46 351ndash354

Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Sharma P and Dubey RSH (2005) Drought induces stress and enhances

the activities of antioxidant enzymes in growing rice seedlings Plant Growth

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effects of Ginkgo biloba against CCl4 induced hepatic injury in rats Ind J

Pharamacol 33 260-266

Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

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peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

SREBP family FEBS J 276616ndash621

Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

Sies H (1997) Oxidative stress oxidants and antioxidants Exp Physiol

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organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

hydroxynonenal by JNKc-Jun overactivation Am J Physiol Gastrointest

Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

(2010) Antioxidant Properties of Ficus Species ndash A Review International

Journal of PharmTech Research CODEN (USA) IJPRIF ISSN 0974-

4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

Sivarajan VV and Balachandran I (1994) Ayurvedic Drugs and their

Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

Smid E J De Witte Y and Gorris L G M (1995) Postharvest Biol

Technol 6 303

Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

Spady DK and Dietschy JM (1988) Interaction of dietary cholesterol and

triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

actions of LDOPA and dopamine in vitro implications for Parkinsons

disease Free Radical Research 24 95-105

Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

Exp Geront 36 1425-1457

Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

218

Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Nutrition 7 407-422

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Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

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lupeol linoleate on lipemicndashoxidative stress in experimental

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

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Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

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Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

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Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

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Manian R Anusuya N Siddhuraju P and Manian S (2008) The

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Ficus racemosa L Food Chemistry 107 1000ndash1007

Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

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Maron DJ (2004) Flavonoids for reduction of atherosclerotic risk Curr

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Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

Yokoyama M Honda M Zen Y Nakanuma Y Miyamoto K and

Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

Joshi-Barve Shirish Barve Craig McClain (2007) Nonalcoholic fatty liver

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Biochemistry 18 184ndash 195

Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

Charaf UK (1983) Hepatic free fatty acids in alcoholic liver disease and

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Mayes AP (1993) Structure and function of the lipid soluble vitamins In

Murray KR Graner KD Mayes AP and Rodwell WV Harperlsquos

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edition 588-

590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

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McCullough AJ (2004) The clinical features diagnosis and natural history

of non-alcoholic fatty liver disease Clinics in Liver Disease 8 521ndash533

McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

Assessing potential bioavallability of raspberry anthocyanins using an in

vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

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Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

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with grid-based energy evaluation Journal of Computational Chemistry 13

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Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Mervat MM and Taie HAA (2009) Antioxidant activities total

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Australian Journal of Basic and Applied Sciences 3(4) 3609-3616

Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

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Michael Metz (2005) Liver function tests IMVS News letter 57

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

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of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

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syndrome in south Asians continuing escalation amp possible solutions Indian

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Nutrition 20482ndash491

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mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

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antioxidant vitamins and trace elements supplemented diets on activities of

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Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

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Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

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oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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action Diabetologia 47170ndash84

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Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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(5) G1135ndashG1139

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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development of non-alcoholic steatohepatitis in a dietary murine model Am

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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Iwama K (2002) The comet assay with 8 mouse organs Results with 39

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Satyavati GV (1982) Some traditional medical systems and practise of

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Ed CRC press Boca RatonFL

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Westernized-likediet-fed rats effect on glucose homeostasis lipid profile

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Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

resistance Proc Nutr Soc 66 33ndash41

Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Indian J Med Res 120 9-11

Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

muscle) Therapie 46 351ndash354

Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

antioxidant studies of Ficus Racemosa Linnroot 13 (4) 70-74

Sharma P and Dubey RSH (2005) Drought induces stress and enhances

the activities of antioxidant enzymes in growing rice seedlings Plant Growth

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effects of Ginkgo biloba against CCl4 induced hepatic injury in rats Ind J

Pharamacol 33 260-266

Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

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peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

Shimada K Fujikawa K Yahara K and Nakamura T (1992)

Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

SREBP family FEBS J 276616ndash621

Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

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82 291-295

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organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

hydroxynonenal by JNKc-Jun overactivation Am J Physiol Gastrointest

Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

(2010) Antioxidant Properties of Ficus Species ndash A Review International

Journal of PharmTech Research CODEN (USA) IJPRIF ISSN 0974-

4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

Sivarajan VV and Balachandran I (1994) Ayurvedic Drugs and their

Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

Smid E J De Witte Y and Gorris L G M (1995) Postharvest Biol

Technol 6 303

Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

266

Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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lupeol linoleate on lipemicndashoxidative stress in experimental

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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activation of AMP-dependent protein kinase Food and Chemical

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piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

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Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

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mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

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Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

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Arch Biochem Biophys 378 259-268

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mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

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alcoholic fatty liver in mice Hepatology 42 568ndash577

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

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Mahmoud MR El-Abhar HS and Saleh S (2002) The effect of Nigella

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Makino I Shinozaki K Yoshino K and Nakagawa S (1975)

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Manco M Calvani M and Mingrone G (2004) Effects of dietary fatty

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Manian R Anusuya N Siddhuraju P and Manian S (2008) The

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Marchand LL Murphy SP Hankin JH Wilkens LR Kolonel LN

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Marchesini G Bugianesi E Forlani G Cerrelli F Lenzi M Manini

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Mari M Caballero F Colell A Morales A Caballeria J Fernandez

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Marimuthu P Wu CL Chang HT and Chang ST (2008) Antioxidant

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Mariod AA Ibrahim RM Ismail M and Ismail N (2009) Antioxidant

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Marra F Gastaldelli A Svegliati Baroni G Tell G and Tiribelli C

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Mates JM Perez-Gomez C and Decastro IN (1999) Clin Chem 32

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Matsuzawa N Takamura T Kurita S Misu H Ota T Ando H

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Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in

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Matsuzawa Y Shimomura I Nakamura T Keno Y Kotani K and

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Matteoni C Younossi Z Gramlich T Boparai N and Liu Y (1999)

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Matthaei S StumvollM Kellerer M and Haring (2000) Endocr H-U

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Matthew Ricci (2008) NAFLD (Non-Alcoholic Fatty Liver Disease) A

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Matthew Cave Ion Deaciuc Christian Mendez Zhenyuan Song Swati

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Mavrelis PG Ammon HV Gleysteen JJ Komorowski RA and

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590

Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro

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McCay PB (1985) Vitamin E Interactions with free radicals and

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McCullough AJ (2004) The clinical features diagnosis and natural history

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McDougall GJ Dobson P Smith P Blake A and Stewart D (2005)

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vitro digestion system Journal of Agricultural and Food Chemistry 53(15)

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Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

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Meng EC Shoichet BK and Kuntz ID (2004) Automated docking

with grid-based energy evaluation Journal of Computational Chemistry 13

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Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Mervat MM and Taie HAA (2009) Antioxidant activities total

anthocyanins phenolics and flavonoids contents of some sweet potato

genotypes under stress of different concentrations of sucrose and sorbito

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Meydani M (2000) Vitamin E and prevention of heart disease in high-risk

patients Nutr Rev 58 278-281

Meyer SA and Kulkarni AP (2001) Hepatotoxicity in Introduction to

biochemical toxicology 3rd

Edition edited by E Hodgson and R C Smart (A

John Wiley amp Sons Inc New York) 487

Mezzetti A Di Ilio C Calafiore AM Aceto A Marzio L Frederici G

and Cuccurullo F (1990) Glutathione peroxidase glutathione reductase and

glutathione transferase activities in the human artery vein and heart J Mol

Cell Cardiol 22 935-938

Michael Metz (2005) Liver function tests IMVS News letter 57

Michalak A (2006) Phenolic compounds and their antioxidant activity in

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Milagro FI Campioacuten J and Martiacutenez JA (2006) Weight gain induced

by high-fat feeding involves increased liver oxidative stress Obesity (Silver

Spring) 14 1118ndash1123

Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

radical scavenging activity of some medicinal and aromatic plant extracts

Food Chemistry 85 231ndash237

Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

of the Lycium barbarum polysaccharides administration on blood lipid

metabolism and oxidative stress of mice fed high-fat diet in vivo Food

Chemistry 113 872ndash877

Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

Metabolic syndrome in children current issues and South Asian perspective

Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

Nutrition 20482ndash491

Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

Udupa UV and Sarma DNK (2000) Effect of HD-03-a herbal

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Pharmacol 44 82-86

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

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ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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development of non-alcoholic steatohepatitis in a dietary murine model Am

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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and adipocyte hormones and their modulation by rosiglitazone and

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Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

muscle) Therapie 46 351ndash354

Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Sharma P and Dubey RSH (2005) Drought induces stress and enhances

the activities of antioxidant enzymes in growing rice seedlings Plant Growth

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effects of Ginkgo biloba against CCl4 induced hepatic injury in rats Ind J

Pharamacol 33 260-266

Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

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peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

SREBP family FEBS J 276616ndash621

Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

Sies H (1997) Oxidative stress oxidants and antioxidants Exp Physiol

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organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

hydroxynonenal by JNKc-Jun overactivation Am J Physiol Gastrointest

Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

(2010) Antioxidant Properties of Ficus Species ndash A Review International

Journal of PharmTech Research CODEN (USA) IJPRIF ISSN 0974-

4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

Sivarajan VV and Balachandran I (1994) Ayurvedic Drugs and their

Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

Smid E J De Witte Y and Gorris L G M (1995) Postharvest Biol

Technol 6 303

Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

Spady DK and Dietschy JM (1988) Interaction of dietary cholesterol and

triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

actions of LDOPA and dopamine in vitro implications for Parkinsons

disease Free Radical Research 24 95-105

Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

Exp Geront 36 1425-1457

Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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lupeol linoleate on lipemicndashoxidative stress in experimental

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

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Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

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Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

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alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

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Mazur A Bayle D Lab C Rock E and Rayssiguier Y (1999)

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Mehta B K Sharma U Pandit V Agrawal S Joshi N and Gupta M

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Merchant JR Bakshi VM and Engineer AB (1979) Chemical

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Edition edited by E Hodgson and R C Smart (A

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Miliauskas G Venskutonis PR and Van Beek TA (2004) Screening of

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Ming M Guanhua L Zhanhai Y Guang C and Xuan Z (2009) Effect

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Misra A Khurana L Vikram NK Goel A and Wasir JS (2007)

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Nutrition 23(11ndash12)895ndash910

Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

syndrome in south Asians continuing escalation amp possible solutions Indian

J Med Res 125(3)345ndash54

Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

syndrome) and obesity in Asian Indians Evidence and implications

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Mithra SK Seshadri SJ Venkataranganna MV Gopumadhavan S

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Modi KP Patel NM and Goyal R K (2008) Estimation of L-topaf from

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Mohamed and Azza M (2008) The ameliorative actions of Agaricus blazei

mushroom against rat liver oxidative damage and fibrosis induced by CCL4

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

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Mohan V and Deepa R (2006) Adipocytokines and The expanding Asian

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Moon YJ Wang X Morris and ME (2006) Toxicol In Vitro 20 187

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Mythilypriya R Shanthi P and Sachdanandam P (2007) Oral acute and

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Naganna B (1989) Plasma proteins In Textbook of Biochemistry and

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Nakamoto K Takayama F Mankura M Hidaka Y Egashira T and

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steatohepatitis summary of an AASLD single topic conference Hepatology

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Lipids 99 11-19

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carotenoids are more bioaccessible from fruits than dark green vegetables

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acute and subchronic toxicity of Stachytarpheta angustifola (Mill) Vahl

(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

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Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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705

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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convenient substrate for determination and study of L-and D-glutamyl trans

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

(2005) Flavonoidndashmembrane interaction a protective role of flavonoids at

the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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compounds isolated from olive oil European Journal of Cancer 36 1235ndash

1247

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glucose amine Japanese Journal of Nutrition 44307-315

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diabetes Science 306457ndash61

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

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Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

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289e298

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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methionine choline-deficient diet J Lipid Res 491068ndash76

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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820

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Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

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and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

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Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

Exp Geront 36 1425-1457

Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

liver diseases Digestive and liver Disease 39 (4) 293-304

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Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Edition edited by E Hodgson and R C Smart (A

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Misra A Misra R Wijesuriya M and Banerjee D (2007) The metabolic

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Misra A Vikram NK (2004) Insulin resistance syndrome (metabolic

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Mohan V (2004) Why are Indians more prone to diabetes J Assoc Phys

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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Oyaizu M (1986) Studies on product of browning reaction prepared from

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Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

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Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

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Biotin in metabolism and its relationship tohuman disease Arch Med Res

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Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

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44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

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85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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(eds) Standard methods of clinical chemistry 6th

ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

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Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Med Hypotheses 60 567-572

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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ginseng prevents the onset of high-fat diet induced hyperglycemia and

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

Page 35: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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antioxidant vitamins and trace elements supplemented diets on activities of

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

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and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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Antioxidant properties of polyphenol-containing extract from soybean

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Wang X and Quinn P (1999) Vitamin E and its function in membranes

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PMID 15046985

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modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

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Preparation and Pharmacological evaluation of plant material England John

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Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

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World Health Organisation (2006) Obesity and overweight Fact sheet 311

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Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

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rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

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dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

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Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 36: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

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(Fam Verbanaceae) extrct in animals Afr J Biotecnol 8(9) 1793-1799

Ogbonnia S Adekunle AA Bosa MK and Enwuru VN (2008)

Evaluation of acute and subacute toxicity of Alstnia congensis Engler

(Apocynaceae) bark and Xylopia aethiopica (Dunal)A Rich (Annonaceae)

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Entada saponin-III a saponin isolated from the bark of Entada phaseoloides

Phytochemistry 26 2789ndash2796

Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

saponins (ES) II and IV from the bark of Entada phaseoloides Chemical and

Pharmaceutical Bulletin 36 1264ndash1269

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

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Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

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Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

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Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

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action Diabetologia 47170ndash84

Pitchersky E and Gang DR (2000) Genetics and biochemistry of

secondary metabolites in plants An evolutionary perspective Trends Plant

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Pompella A Visvikis A and Paolicchi A (2003) The changing faces of

glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

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Pryor WA (1993) Measurement of oxidative stress status in humans

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85ndash88

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Rahman NN Khan M and Hasan R (1994) Bioactive components from

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Rajesh MG and Latha MS (2004) Preliminary evaluation of the

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

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nutraceutical applications of black cumin (Nigella sativa L) an overview

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Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

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abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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710-723

Reitman S Frankel S (1957) Amer JClin Path 2856

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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(5) G1135ndashG1139

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

Roy S Sehgal R Pahdy BM and Kumar VL (2005) Antioxidant and

protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

(2008) Micellarisation of carotenoids from raw and cooked vegetables

Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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development of non-alcoholic steatohepatitis in a dietary murine model Am

J Physiol Gastrointest Liver Physiol 287 G264-G273

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antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

RK (2002) Antiulcerogenic activity of methanolic extract of Emblica

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Sallie R Tredgr JM and William (1999) Drugs and the liver Biopharm

Drug Dispos 12 251-259

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Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

AJ and Shulman GI (2004) Mechanism of hepatic insulin resistance in

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

Sarabu R and Tilley J (2005) Annu Rep Med Chem 40 167e181

Elsevier Academic Press

Sasaki YF Kawaguchi S KamayaA OhshitaM Kabasawa K and

Iwama K (2002) The comet assay with 8 mouse organs Results with 39

currently used food additives Mutation ResearchGenetic Toxicology and

Environmental Mutagenesis 519 103ndash109

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Sauberlich HE (1999) Laboratory tests for the assessment of nutritional

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Ed CRC press Boca RatonFL

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and adipocyte hormones and their modulation by rosiglitazone and

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Scherer R and Godoy HT (2009) Antioxidant activity index (AAI) by the

22- diphenyl-1-picrylhydrazyl method Food Chemistry 112 654ndash658

Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

resistance Proc Nutr Soc 66 33ndash41

Scott MD Lubin BH Zuo L and Kuypers FA (1991) Erythrocyte

defence against hydrogen peroxide Preeminent importance of catalase J

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Seth and Bhawana Sharma (2004) Medicinal plants in India Commentary

Indian J Med Res 120 9-11

Sgro C and Escousse A (1991) Side effects of fibrates (except liver and

muscle) Therapie 46 351ndash354

Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

antioxidant studies of Ficus Racemosa Linnroot 13 (4) 70-74

Sharma P and Dubey RSH (2005) Drought induces stress and enhances

the activities of antioxidant enzymes in growing rice seedlings Plant Growth

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Shenoy KA Somayaji SN and Bairy KL (2001) Hepatoprotective

effects of Ginkgo biloba against CCl4 induced hepatic injury in rats Ind J

Pharamacol 33 260-266

Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

Y and Yoshimura K (2002) ―Regulation and function of ascorbate

peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

Shimada K Fujikawa K Yahara K and Nakamura T (1992)

Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

SREBP family FEBS J 276616ndash621

Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

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82 291-295

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organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

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Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

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Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

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alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

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Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Oguzhan B Sancho V Acitores A Villanueva-Penacarrillo ML

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Okada Y Shibata S Javellana AMJ and Kamo O (1988) Entada

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Oteiza PI Erlejman AG Verstraeten SV Keen CL and Fraga CG

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the membrane surface Clin Dev Immunol 12 (1) 19ndash25

Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

Bartsh H (2000) The antioxidantanticancer potential of phenolic

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Oyaizu M (1986) Studies on product of browning reaction prepared from

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Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN and Ozdelen E

(2004) Endoplasmic reticulum stress links obesity insulin action and type 2

diabetes Science 306457ndash61

Ozturk-Urek R Bozkaya LA and Tarhan L (2001) The effects of some

antioxidant vitamins and trace elements supplemented diets on activities of

SOD CAT GSH-Px and LPO levels in chicken tissues Cell Biochemistry

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Pacheco-Alvarez D Solorzano-Vargas RS and Leon-Del-Rio A (2002)

Biotin in metabolism and its relationship tohuman disease Arch Med Res

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Pacher P Beckman JS and Liaudet L (1997) (Nitric oxide and

peroxynitrite in health and disease Physiol Rev 87 (1) 315ndash424

Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

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Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

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1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

Ramadan MF and Moumlrsel JT (2004) Oxidative stability of black cumin

(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

Rao KS (2009) Free radical induced oxidative damage to DNA relation to

brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

Changes in peroxidases activity Plant Cell Physiol 26 987- 994

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

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fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Med Hypotheses 60 567-572

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

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Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

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Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

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Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

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Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

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Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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gastroenterology (Brandt LJEd) Churchil Livingstone Philadelphia 812-

820

Rosenberg HR (1992) Chemistry and Physiology of the citamins Inter

Science Publishers Inc New York 452-453

Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

rat nonalcoholic fatty liver disease model Atherosclerosis 206 119ndash126

Roy S Sehgal R Pahdy BM and Kumar VL (2005) Antioxidant and

protective effect of Calotropis procera against alloxan-induced diabetics in

rats J Ethanopharmacol 102 470-473

Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

(2008) Micellarisation of carotenoids from raw and cooked vegetables

Plant Foods for Human Nutrition 63(3) 127minus133

Sadasivam S Manickam A (1997) Biochemical methods Second edition

Newage international Pvt Ltd

Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

(2004) Up regulation of osteopontin expression is involved in the

development of non-alcoholic steatohepatitis in a dietary murine model Am

J Physiol Gastrointest Liver Physiol 287 G264-G273

Sahreen S Rashid Khan M and Ali Khan R (2010) Evaluation of

antioxidant activities of various solvent extracts of Carissa opaca fruits

Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

RK (2002) Antiulcerogenic activity of methanolic extract of Emblica

Officinalis Journal of Ethanopharmacology 82 1-9

Sallie R Tredgr JM and William (1999) Drugs and the liver Biopharm

Drug Dispos 12 251-259

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Woods S A (1996) J Entomol Sci 31 453

Samuel VT Liu ZX Qu X Elder BD Bilz S Befroy D Romanelli

AJ and Shulman GI (2004) Mechanism of hepatic insulin resistance in

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

mitochondrial abnormalities Gastroenterology 120 (5) 1183ndash1192

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Satheesh AM and Pari L (2004) Antioxidant effect of Boerhavia diffusa

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Satyavati GV (1982) Some traditional medical systems and practise of

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Sauberlich HE (1999) Laboratory tests for the assessment of nutritional

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Ed CRC press Boca RatonFL

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

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Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Owen R W Giacosa A Hull W E Haubner R Spiegelhalder B and

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Oyaizu M (1986) Studies on product of browning reaction prepared from

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Pacher P Beckman JS and Liaudet L (2007) Nitric oxide and

peroxynitrite In health and disease Physiological Reviews 87(1) 315ndash424

Paetau I Khachik F Brown ED Beecher GR Kramer TR and

Chittams J (1998a) Bioavailability of tomato carotenoids from lycopene-

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A544minusA

Pan HZ Zhang H Chang D Li H and Sui H (2008) The change of

oxidative stress products in diabetes mellitus and diabetic retinopathy Br J

Ophthalmol 92 548ndash51

Paradis V Perlemuter G Bonvoust F Dargere D Parfait B and

Vidaud M (2001) High glucose and hyperinsulinemia stimulate connective

tissue growth factor expression a potential mechanism involved in

progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34738ndash

44

Paranjpe P (2001) Indian Medicinal Plants Forgotten Healers A Guide to

Ayurvedic Herbal Medicine Chaukhamba Sanskrit Pratisthan Delhi p316

Park CH Yamabe N Noh JS Kang KS Tanaka T Yokozawa T

(2009b) The beneficial effects of morroniside on the inflammatory response

and lipid metabolism in the liver of dbdb mice Biol Pharm Bull 32 1734ndash

1740

Parrotta JA (2006) Healing Plants of Peninsular India CABI Publishing

523ndash524

Patchett AA and Nargund RP (2000) Annu Rep Med Chem 35

289e298

Pauly Nicolas Pucciariello C Mandon K Innocenti G Jamet A

Baudouin E Herouart D Frendo P and Puppo A (2006) Reactive

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Peach and Tracey MV (1955) In modern methods of plant analyse 4

373-374

Perez C Canal JR and Torres MD (2003) Experimental diabetes treated

with Ficus carica extract effect on oxidative stress parameters Acta

Diabetologica 40 3ndash8

Perez-Amador MC Ocotero VM Castaneda JMG and Esquinca

ARG (2007) Alkaloids in Solanum torvum Sw (Solanaceae) International

Journal of Experimental Botany 76 39-45

Perry G Cash AD Srinivas R and Smith MA (2002) Metals and

oxidative homeostasis in Alzheimerlsquos disease Drug Development and

Research 56 293ndash299

Pietta PG (2000) Flavonoids and antioxidants J Nat Prod 63 1035-

1042

Pignatelli P Pulcinelli FM and Lenti L (1998) Hydrogen Peroxide Is

Involved in Collagen-Induced Platelet Activation Blood 91 (2) 484-490

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action Diabetologia 47170ndash84

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secondary metabolites in plants An evolutionary perspective Trends Plant

Sci 5 445-459

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glutathione a cellular protagonist [J] Biochem Pharmacl 66(8) 1499-1503

Prasad K (2010) Effects of vitamin E on serum enzymes and electrolytes in

hypercholesterolemia Molecular Cellular Biochemistry 335 67ndash74

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oxidative damage in rat tissues and its attenuation by dietary sesame oil

Food Chem Toxicol 43 299ndash306

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Cancer Epidemiol Biomarkers Prev 2 289-292

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Fenton-type reactions influence of the iron chelator Phytochemistry 31

85ndash88

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dehydrogenase in response to cerebral ischemia in rat brain Indian J Clin

Biochem 18 64-70

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Ficus glomerata Pure and Applied Chemistry 66 2287ndash2290

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antihepatotoxic activity of Kamilari a polyherbal formulation J

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Rajkapoor B Anandan R and Jayakar B (2002) Anti-ulcer effect of

Nigella sativa Linn against gastric ulcers in rats Curr Sci 82 177ndash179

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nutraceutical applications of black cumin (Nigella sativa L) an overview

International Journal of Food Science and Technology 42 1208ndash1218

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(Nigella sativa L) coriander (Coriandrum sativum L) and niger (Guizotia

abyssinica Cass) crude seed oils upon stripping Eur J Lipid Sci Technol

106 35ndash43

Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

Research 41 77ndash83

Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

(2002) Glucose lowering efficacy of Ficus racemosa barks extract in normal

and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

Gastroprotective effect of standardized extract of Ficus glomerata fruit on

experimental gastric ulcers in rats Journal of Ethnopharmacology 115

323ndash326

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brain aging and neurological disorders Indian J Biochem Biophys 46 9ndash15

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Free Radical Biol Med 26 1231ndash1237

Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

Evans C (1999) Antioxidant activity applying in an improved radical cation

decolorisation assay Free Radical Biol Med 26 1231-1237

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peroxidation ndashBiochemistry measurement and signified in liver cell injury in

toxicology in the liver edited by G L Plea and W R Hewilt (Raven press

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induced response of photosynthesis and antioxidant metabolism in higher

plants J Plant Physiol 161(11) 1189-1202

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and benzyl adenine and dark- treated graving rice (Oryza sativa) leaves II

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710-723

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ed New York Academic

press 6 215-222

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activity relationships of flavonoids and phenolic acids J Free Radic Biol

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

RM (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic

methionine choline-deficient diet J Lipid Res 491068ndash76

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efficacies of Cassia fistula An Indian labrum African Journal of Pharmacy

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

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oxidative stress on catalase and MnSOD gene transcription in astrocytes

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Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Antioxidant properties of polyphenol-containing extract from soybean

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820

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Rosselli MS Adriana L Burgue˜nob Julieta Carabelli Mariano Schumanb

Carlos J Pirolab and Silvia Sookoiana (2009) Losartan reduces liver

expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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protective effect of Calotropis procera against alloxan-induced diabetics in

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Ryan L OConnell O OSullivan L Aherne SA and OBrien NM

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Plant Foods for Human Nutrition 63(3) 127minus133

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Sagi Y and Youdim MBH (2008) The neuroprotective effect of

ladostigil against hydrogen peroxide-mediated cytotoxicity Chem-Biol

Interact 175 318ndash26

Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2001) Nonalcoholic fatty liver disease a medical consequence

of globalisation Indian JGastroenterol 20 215-216

Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Schrauwen P (2007) High-fat diet muscular lipotoxicity and insulin

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Antioxidative properties of xanthan on the autoxidation of soybean oil in

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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failure Exp Gerontol 39 825-830

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Phytochemical and antioxidant characterization of Hypericum perforatum

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Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

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Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

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Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Med Hypotheses 60 567-572

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

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pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

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Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

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human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Sahai A Malladi P Melin-Aldana H Green RM and Whitington PF

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Food Chemistry 122 1205ndash1211

Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Sen CK (1995) Oxygen toxicity and antioxidants state of the art Int J

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Sen CK (2003) The general case for redox control of wound repair

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Sharma SK and Gupta VK (2008) PHCOG MAGRearch article In vitro

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Sharma P and Dubey RSH (2005) Drought induces stress and enhances

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Shigeoka S Ishikawa T Tamoi M Miyagawa Y Takeda T Yabuta

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peroxidise isoenzymes J Exp Bot 53(372) 1305-1319

Shimada K Fujikawa K Yahara K and Nakamura T (1992)

Antioxidative properties of xanthan on the autoxidation of soybean oil in

cyclodextrin emulsion J Agric Food Chem 40 945ndash948

Shimano H (2009) SREBPs physiology and pathophysiology of the

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

AC (2004) Influence of age and vitamin E on post-ischemic acute renal

failure Exp Gerontol 39 825-830

Shoelson SE Lee J and Goldfine AB (2006) Inflammation and insulin

resistance J Clin Invest 116 1793ndash1801

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

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Gastroenterol Hepatol 42(4) 485-492

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organs Philos Trans R Soc Lond B Biol Sci 311 617-631

Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

hydroxynonenal by JNKc-Jun overactivation Am J Physiol Gastrointest

Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

Sivarajan VV and Balachandran I (1994) Ayurvedic Drugs and their

Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

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Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

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fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

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curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

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Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

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lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

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J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

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Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

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piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

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and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

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Rao KS (2009) Free radical induced oxidative damage to DNA relation to

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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Richter C (1987) Biophysical consequences of lipid peroxidation in

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Rinella ME Elias MS Smolak RR Fu T Borensztajn J and Green

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Robert M (2006) Mineral surfaces and the prebiotic selection and

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Roberts CK Barnard RJ Sindhu RK Jurczak M Ehdaie A and

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

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Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

and steatohepatitis II Cytochrome P-450 enzymes and oxidative stress

American Journal of Physiology Gastrointestinal and Liver Physiology 281

(5) G1135ndashG1139

Roe J H and Keuther C A (1943) The determination of ascorbic acid in

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Rohrdanz E Schmuck G Ohler S and Kahl R (2001) The influence of

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guinea pigs Free Radic Biol Med 21 907-15

Romeo S Sentinelli F Dash S Yeo GS Savage DB Leonetti F

Capoccia D Incani M Maglio C Iacovino M OlsquoRahilly S and Baroni

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Romero AM Mirtha MD Sturia MA and Judis MA (2004)

Antioxidant properties of polyphenol-containing extract from soybean

fermented with Saccharomyces cerevisiae Eur J Lipid Sci Technol 106

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Rosen HR and Keefe EB (1998) Laboratory evaluation of the patient

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Gastroenterology 123 1705ndash1725

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Nonalcoholic steatohepatitis association of insulin resistance and

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Rev Mol Cell Biol 9 162ndash176

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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spontaneous lipid peroxidation following glutathione depletion Plant Med

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Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

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Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

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alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

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Randhawa MA and Al-Ghamdi MS (2002) A review of the

pharmacotherapeutic effects of Nigella sativa Pakistan Journal of Medical

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Rao BR Murugresan T Sinha S Saha BP Pal M and Mandal SC

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and alloxan diabetic rats Phytotherapy Research 16 590ndash592

Rao CV Arti R Verma M Vijayakumar S Rastogi (2008)

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Re R Pellegrini N Proteggente A Pannala A Yang M and Rice-

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and antioxidant enzymes in diet-induced metabolic syndrome Metabolism

55 928ndash934

Robertson G Leclercq I and Farrell GC (2001) Nonalcoholic steatosis

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expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

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Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

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piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

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Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

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Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

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oxidative stress Biol Res Biol 33(2) 55ndash64

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Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

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Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

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Verma S and Singh SP (2008) Current and future status of herbal

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Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

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Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

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Wang X and Quinn P (1999) Vitamin E and its function in membranes

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Sairam K Rao ChV Babu MD Kumar V Agarwal VK and Goel

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Sanyal AJ (2002) GA technical review on nonalcoholic fatty liver disease

Gastroenterology 123 1705ndash1725

Sanyal AJ Campbell-Sargent C Mirshahi F Rizzo WB Contos MJ

Sterling RK Luketic VA Shiffman ML and Clore JN (2001)

Nonalcoholic steatohepatitis association of insulin resistance and

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

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Ethanopharmacol 112 514-524

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Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

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Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Teli MR James OF Burt AD Bennett MK and Day CP (1995)

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Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

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varieties cumin black cumin and bitter cumin on antioxidant systems Eur

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Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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patients with cirrhosis and after liver transplantation Hepato-

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

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activation of AMP-dependent protein kinase Food and Chemical

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Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

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Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

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Trivedi CP Shinde S and Sharma RC (1969) Preliminary

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(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

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644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

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starvation its mechanism via tissue mobilization of cholesterol

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

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pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

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Taylor and Francis (2000) Toxicology of the Human Environment - the

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Teli MR James OF Burt AD Bennett MK and Day CP (1995)

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Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

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in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

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varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

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activation of AMP-dependent protein kinase Food and Chemical

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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Targher G Bertolini L Padovani R Poli F Scala L Zenari L

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Teli MR James OF Burt AD Bennett MK and Day CP (1995)

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Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

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Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

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activation of AMP-dependent protein kinase Food and Chemical

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Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

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hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

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mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

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Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

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Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

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Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

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Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

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Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

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J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

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mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

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Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

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Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

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triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

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Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

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Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

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high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

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Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

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Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

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Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

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L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

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Med 20 693-702

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Shimizu MH Araujo M Borges SM De Tolassa EM and Seguro

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Singanan V Singana M and Begum H (2007) The hepatoprotective

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Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

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Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

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Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

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Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

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Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

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Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

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Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

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Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

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Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

218

Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

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Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

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Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

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Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

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Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

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Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

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Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 48: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Shukla R Gupta S Gambhir JK Prabhu KM and Murthy PS (2004)

Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in

hypercholesterolaemic rabbits Journal of Ethnopharmacology 92 47ndash51

Sido B Hack V and Hochlehner A (1998) Impairment of intestinal

glutathione synthesis in patients with inflammatory bowel disease [J] Int J

Gastroenterol Hepatol 42(4) 485-492

Sies H (1997) Oxidative stress oxidants and antioxidants Exp Physiol

82 291-295

Sies H and Cadenas E (1985) Oxidative stress damage to intact cells and

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Silva BA Ferreres F Malva JO and Dias ACP (2005)

Phytochemical and antioxidant characterization of Hypericum perforatum

alcoholic extracts Food Chemistry 90 157ndash167

Singanan V Singana M and Begum H (2007) The hepatoprotective

effect of Bael leaves in alcohol induced liver injury in albino rats

International J Science and Technology 2(2) 83-92

Singh M Govindarajan R Nath V Singh RAK and Mehrotra S

(2006) Antimicrobial wound healing and antioxidant activity of

Plagiochasma appendiculatum Lehm et Lind Journal of

Ethanopharamacology 107 67-72

Singh R Wang Y Schattenberg JM Xiang Y and Czaja MJ (2009)

Chronic oxidative stress sensitizes hepatocytes to death from 4-

hydroxynonenal by JNKc-Jun overactivation Am J Physiol Gastrointest

Liver Physiol 297 G907-G917

Singh SP Nayak S and Swain M (2004) Prevalence of non-alcoholic

fatty liver disease in coastal eastern India a preliminary ultrasonographic

survey Trop Gastroentrol 25 76-9

Sirisha N Sreenivasulu M Sangeeta K and Madhusudhana Chetty C

(2010) Antioxidant Properties of Ficus Species ndash A Review International

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4304 Vol2 No4 pp 2174-2182 Oct-Dec 2010

Sivarajan VV and Balachandran I (1994) Ayurvedic Drugs and their

Plant Source Oxford and IBH Publishing Co Pvt Ltd New Delhi India

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Technol 6 303

Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

266

Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

Spady DK and Dietschy JM (1988) Interaction of dietary cholesterol and

triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

actions of LDOPA and dopamine in vitro implications for Parkinsons

disease Free Radical Research 24 95-105

Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

Exp Geront 36 1425-1457

Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

218

Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

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Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

liver diseases Digestive and liver Disease 39 (4) 293-304

Stief TW (2003) The physiology and pharmacology of singlet oxygen

Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

(1985) Dietary supplementation with Vitamin E in hyperlipoproteinemias

effects on plasma lipid peroxides antioxidant activity prostacyclin

generation and platelet aggregability Thrombosis and Haemostasis 54 425ndash

430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 49: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Smirnoff N (2001) ―L-ascorbic acid biosynthesis Vitam Horm 61 241-

266

Smirnoff N Cumbes QJ (1989) Hydroxyl radical scavenging activity of

compatible solutes Phytochemistry 281057-1060

Solga S Alkhuraishe AR and Clark JM (2004) Dietary composition

and non-alcoholic fatty liver disease Dig Dis Sci 491578ndash83

Son IS Kim JH Sohn HY Son KH Kim JS and Kwon CS

(2007) Antioxidative and hypolipidaemic effects of diosgenin a steroidal

saponin of yam (Dioscorea spp) on high-cholesterol fed rats Bioscience

Biotechnology and Biochemistry 71 3063ndash3071

Song BJ Moon KH and Olsson NU (2008) Prevention of alcoholic

fatty liver and mitochondrial dysfunction in the rat by long-chain

polyunsaturated fatty acids J Hepatol 49 262ndash273

Song Y Manson JE Buring JE Sesso HD and Liu S (2005) J Am

Coll Nutr 24 376e384

Sookoian S Castanlsquoo GO Burguenlsquoo AL Gianotti TF Risselli MS

and Pirola CJ (2009) J Lipid Res 52 2111ndash2116

Spady DK and Dietschy JM (1988) Interaction of dietary cholesterol and

triglycerides in the regulation of hepatic low density lipoprotein transport in

the hamster The Journal of Clinical Investigation 81 300ndash309

Spencer JP Jenner A Butler J Aruoma OI Dexter DT Jenner P

and Halliwell B (1996) Evaluation of the pro-oxidant and antioxidant

actions of LDOPA and dopamine in vitro implications for Parkinsons

disease Free Radical Research 24 95-105

Spiteller G (2001) Lipid peroxidation in aging and age-dependent diseases

Exp Geront 36 1425-1457

Spolarics Z and Meyenhofer M (2000) Augmented resistance to oxidative

stress in fatty rat livers induced by a short-term sucrose-rich diet Biochim

Biophys Acta 1487 190-200

Sreejayan N and Rao MNA (1997) Nitric oxide scavenging by

curcuminoids Journal of Pharmacy and Pharmacology 49 105ndash107

Srivastava V (2008) Bioinformation 3 180 [PMID 19238244]

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

218

Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

Chemical Society Washington DC 223

Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

liver diseases Digestive and liver Disease 39 (4) 293-304

Stief TW (2003) The physiology and pharmacology of singlet oxygen

Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

(1985) Dietary supplementation with Vitamin E in hyperlipoproteinemias

effects on plasma lipid peroxides antioxidant activity prostacyclin

generation and platelet aggregability Thrombosis and Haemostasis 54 425ndash

430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 50: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Stadlbauer V Fickert P Lackner C Schmerlaib J Krisper P Trauner

M and Stauber RE (2005) Hepatotoxicity of NONI juice Report of two

cases World J Gastroenterol 11 4758ndash4760

Stadtman ER and Levine RL (2003) Free radical-mediated oxidation of

free amino acids and amino acid residues in proteins Amino Acids 25 207-

218

Stanner SA Hughes J Kelly CN and Buttriss JA (2004) Review of

the epidemiological evidence for the antioxidant hypotheses Public Health

Nutrition 7 407-422

Steiner RP (1986) Folk Medicine ndash The Art and the Science American

Chemical Society Washington DC 223

Stickel F and Schuppan D (2007) Herbal medicine in the treatment of

liver diseases Digestive and liver Disease 39 (4) 293-304

Stief TW (2003) The physiology and pharmacology of singlet oxygen

Med Hypotheses 60 567-572

Stiehl A Walker S Stiehl L Rudolph G Hofmann WJ and

Theilmann L (1994) Effect of ursodeoxycholic acid on liver and bile duct

disease in primary sclerosing cholangitis A 3-year pilot study with a

placebo-controlled study period J Hepatol 20 57ndash64

Sudhahar V Kumar SA and Varalakshmi P (2006) Role of lupeol and

lupeol linoleate on lipemicndashoxidative stress in experimental

hypercholesterolemia Life Science 78 1329ndash1335

Sun Q Ma J Campos H Hankinson SE Manson JE and Stampfer

MJ (2007) A prospective study of trans fatty acids in erythrocytes and risk

of coronary heart disease Circulation 115 1858ndash1865

Sun WY Wei W Wu L Gui SY and Wang H (2007) Effects and

mechanisms of extract from Paeonia lactiflora and Astragalus

membranaceus on liver fibrosis induced by CCl4 in rats J

Ethanopharmacol 112 514-524

Suntress ZA and Sheck PN (1995) Prevention of lung injury by

tocopherol lipsome J Drug target 3 201

Suresh PS Kumar A Kumar R and Singh VP (2008) An in silico

[correction of insilico] approach to bioremediation laccase as a case study

J Mol Graph Model 26 (5) 845ndash9 doi101016jjmgm200705005

PMID 17606396

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

(1985) Dietary supplementation with Vitamin E in hyperlipoproteinemias

effects on plasma lipid peroxides antioxidant activity prostacyclin

generation and platelet aggregability Thrombosis and Haemostasis 54 425ndash

430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 51: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Swanr JC and Connor WE (1975) Hypercholesterolemia of total

starvation its mechanism via tissue mobilization of cholesterol

AmJPhysiol 229 365-369

Szczeklik A Gryglewski RJ Domagala B Dworski R and Basista M

(1985) Dietary supplementation with Vitamin E in hyperlipoproteinemias

effects on plasma lipid peroxides antioxidant activity prostacyclin

generation and platelet aggregability Thrombosis and Haemostasis 54 425ndash

430

Szeto YT Tomlinson B and Benzie IF (2002) Total antioxidant and

ascorbic acid content of fresh fruits and vegetables Implications for dietary

planning and Food preservation British J Nutr 87 55-59

Taher A Ismaeel H and Cappellini MD (2006) Thalassemia intermedia

revisited Blood Cells Mol Dis 37 12-20

Tapondjou AL Miyamoto T Mirjolet JF Guilbaud N and Lacaille-

Dubois MA (2005) Pursaethosides AndashE triterpene saponins from Entada

pursaetha Journal of Natural Products 68 1185ndash1190

Targher G Bertolini L Padovani R Poli F Scala L Zenari L

Zoppini G and Falezza G (2006) Non-alcoholic fatty liver disease is

associated with carotid artery wall thickness in diet-controlled type 2 diabetic

patients J Endocrinol Invest 29 55ndash60

Taylor and Francis (2000) Toxicology of the Human Environment - the

critical role of free radicals London

Teli MR James OF Burt AD Bennett MK and Day CP (1995)

The natural history of nonalcoholic fatty liver a follow-up study

Hepatology 22 1714ndash1719

Tetri LH Basaranoglu M Brunt EM Yerian LM and Neuschwander-

Tetri BA (2008) Severe NAFLD with hepatic necroinflammatory changes

in mice fed trans fats and a high-fructose corn syrup equivalent Am J

Physiol Gastrointest Liver Physiol 295 G987ndashG995

Thippeswamy NB and Naidu AK (2005) Antioxidant potency of cumin

varieties cumin black cumin and bitter cumin on antioxidant systems Eur

Food Res Technol 220 472ndash476

Tietge UJ Boker KH Bahr MJ Weinberg S Pichlmayr R Schmidt

HH and Manns MP (1998) Lipid parameters predicting liver function in

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 52: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

patients with cirrhosis and after liver transplantation Hepato-

gastroenterology 45(24) 2255-2260

Tietz NW (1970) Fund of Clin Chem P 447

Tilak Khanal Jae Ho Choi Yong Pil Hwang Young Chul Chung Hye

Gwang Jeong (2009) Protective effects of saponins from the root of

Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the

activation of AMP-dependent protein kinase Food and Chemical

Toxicology 47 2749ndash2754

Ting LP (1982) Plant physiology Addison Wesley Services in Life

Sciences New York USA

Tiwari O P and Tripathi Y B (2007) Antioxidant properties of different

fractions of Vitex negundo Linn Food Chemistry 100 1170ndash1176

Toledo FGS Sniderman AD and Kelley DE (2006) Influence of

hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in

type 2 diabetes Diabetes Care 29 1845ndash50

Tomomichi Chonan Hiroaki Tanaka Daisuke Yamamoto Miyoko Yashiro

Takahiro Oi Daisuke Wakasugi Ayumi Ohoka-Sugita Fusayo Io Hiroko

Koretsune Akira Hiratate (2010) Design and synthesis of disubstituted (4-

piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase

inhibitors Bioorganic amp Medicinal Chemistry Letters 20 3965ndash3968

Townsend KL Lorenzi MM and Widmaier EP (2008) High-fat diet-

induced changes in body mass and hypothalamic gene expression in wild-

type and leptindeficient mice Endocrine 33 176ndash188

Trenam CW Blake DR and Morris CJ (1992) Skin inflammation

reactive Oxygen Species and the role of iron Journal of Investigation

Dermatology 99 675-682

Trinder P (1969) Ann Clin Biochem 6 24

Trivedi CP Shinde S and Sharma RC (1969) Preliminary

phytochemical and pharmacological studies on Ficus racemosa extract

(Gular) Indian J Med Res 57 (6) 1070ndash1074

Tuck KL and Hayball PJ (2002) Major phenolic compounds in olive oil

metabolism and health effects Journal of Nutritional Biochemistry 13 636ndash

644

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 53: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Tundis R Bonesi M Deguin B Loizzo MR Menichini F Conforti F

and Menichini F (2009) Cytotoxic activity and inhibitory effect on nitric

oxide production of triterpene saponins from the roots of Physospermum

verticillatum (Waldst and Kit) (Apiaceae) Bioorganic and Medicinal

Chemistry 17 4542ndash4547

Uchida K (2003) 4-Hydroxy-2-nonenal a product and mediator of

oxidative stress Prog Lipid Res 42 318-343

Upadhyay RK Pandey MB Jha RN and Pandey VB (2001)

Eclalbatin triterpine saponins from Eclipta alba J Asian Nat Prod Res 3

213-217

Upasani CD and Balaraman R (2001) Effect of vitamin e vitamin C and

spirulina on the levels of membrane bound enzymes and lipids in some

organs of rats exposed to lead Indian J Pharm 33 185-191

Urmila Thatte (2004) Challenges in clinical research on Herbs Indian

JNat Prod 19 (1) 35-36

Urquiaga I and Leighton F (2000) Plant polyphenol antioxidants and

oxidative stress Biol Res Biol 33(2) 55ndash64

Ur-Rahman A Sohail M Ahmed S Iqbal Choudhary M and Ur-

Rahman H (1985) Heterocycles 23 953ndash955

Valko M Leibfritz D Moncol J Cronin MT Mazur M and Telser J

(2007) Free radicals and antioxidants in normal physiological functions and

human disease International Journal of Biochemistry and Cell Biology 39

44ndash84

Valko M Rhodes CJ Moncol J Izakovic M and Mazur M (2006)

Free radicals metals and antioxidants in oxidative stress-induced cancer

Chem-Biol Interact 10 1ndash40

Van den Berg R Haenen GRMM Van den Berg H and Bast A

(1999) Applicability of an improved Trolox equivalent antioxidant capacity

(TEAC) assay for evaluation of antioxidant capacity measurements of

mixtures Food Chem 66 511-517

Varela-Rey M Embade N Ariz U Lu SC Mato JM and Martinez-

Chantar ML (2009) Non-alcoholic steatohepatitis and animal models

Understanding the human disease The International Journal of Biochemistry

and Cell Biology 41 969ndash976

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 54: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Venkat Ratnam D Ankolaa D Bhardwaja V Sahanaa DK and Ravi

Kumar MNV (2007) Role of antioxidants in prophylaxis and therapy a

pharmaceutical perspective Journal of Controlled Release 113(3) 189-207

Venukumar MR and Latha MS (2004) Effect of Coscinium fenestratum

on hepatotoxicity in rats Indian J of Exp Bio 42 792-97

Verma A Vijayakumar M Chandana V Rao Chandra S and Mathela

(2010) In vitro and In vivo antioxidant properties and DNA damage

protective activity of green fruit of Ficus glomerata Food and Chemical

Toxicology 48 704ndash709

Verma S and Singh SP (2008) Current and future status of herbal

medicines Vet World 1 347ndash50

Vetelainen R van Vliet A and vcan Gulik TM (2007) Essential

pathogenic and metabolic differences in steatosis induced by choline or

methionine-choline deficient diets in a rat model J Gastroenterol Hepatol

221526-1533

Vichnvetskaia KD and Roy DN (2001) Oxidative stress and

antioxidative defence with an emphasis on plants antioxidants Environ Rev

7 31-35

Videla LA Rodrigo R Orellana M Fernandez V Tapia G Quintildeones

L Varela N Contreras J Lazarte R Csendes A Rojas J Maluenda

F Burdiles P Diaz JC Smok G Thielemann L and Poniachik J

(2004) Oxidative stress-related parameters in the liver of non-alcoholic fatty

liver disease patients Clin Sci (Lond) 106 261-268

Villanova N Moscatiello S and Ramillis S (2005) Endothelial

dysfunction and cardiovascular risk profile in nonalcoholic steatohepatitis

Am J Gastroenterol 99 1497ndash1502

Vinson JA Zubik L Bose P Samman N Proch J (2005) Dried fruits

excellent invitro and in vivo antioxidants Journal of the American College of

Nutrition 24 44ndash50

Viuda-Martos M Navajas Y R Zapata E S Fernandez-Lopez J and

Perez-Alvarez J A (2010) Antioxidant activity of essential oils of five

spice plants widely used in a Mediterranean diet Flavour and Fragrance

Journal 25 13minus19

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 55: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Vural H Aksoy N and Ozbilge H (2004) Alterations of oxidative

antioxidative status in human cutaneous lishmaniasis Cell Biochem Funct

22 153-156

Wakil SJ Stoops JK and Joshi VC (1983) Fatty acid synthesis and its

regulation Ann Rev Biochem 52 537ndash579

Wang J Li J Zou Y Chenga W Lu C Zhang L Gea J Huanga C

Jin Y Xiong-wen Lv Cheng-mu Hu and Li-ping Liu (2009) Preventive

effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats

fed with high fat diet Journal of Ethnopharmacology 121 54ndash60

Wang K Zhang Y and Yang C (2005) Antioxidant phenolic compounds

from rhizomes of Polygonum paleaceum Journal of Ethnopharmacology

96 483ndash487

Wang LF and Zhang HY (2003) A theoretical investigation on DPPH

radical-scavenging mechanism of Edaravone Bioorg Med Chem Lett 13

3789ndash3792

Wang X and Quinn P (1999) Vitamin E and its function in membranes

Prog Lipid Res 38(4) 309-336

Wang Y Beydoun MA Liang L Caballero B and Kumanyika SK

(2008) Will all Americans become overweight or obese Estimating the

progression and cost of the US obesity epidemic Obesity (Silver Spring) 16

2323ndash2330

Wasan KM Najafi S Wong J and Kwong M (2001) Assessing plasma

lipid levels body weight and hepatic and renal toxicity following chronic oral

administration of a water soluble phytostanol compound FM-vp4 to gerbils

J Pharm Sci (wwwualberta ca-csps) 4 228-234

Watts GF and Gan SK (2008) Nutrition and metabolism non-alcoholic

fatty liver diseasemdashpathogenesis cardiovascular risk and therapy Curr Opin

Lipidol 19 92ndash4

Wei BQ Weaver LH Ferrari AM Matthews BW and Shoichet BK

(2004) Testing a flexible-receptor docking algorithm in a model binding

site J Mol Biol 337 (5) 1161ndash82 doi101016jjmb200402015

PMID 15046985

Weltman MD Farell GC and Hall P (1998) Hepatic cytochrome P450

2E1 is increased in patients with non-alcoholic steatohepatitis Hepatology

27 128-133

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 56: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Weltman MD Farrell GC and Liddle C (1996) Increased hepatocyte

CYP2E1 expression in a rat nutritional model of hepatic steatosis with

inflammation Gastroenterology 111 1645-1653

Westerbacka J Lammi K and Hakkinen AM (2005) Dietary fat content

modifies liver fat in overweight non-diabetic subjects J Clin Endocrinol

Metab 90 2804ndash9

Wickens AP (2001) Aging and the free radical theory Respiration

Physiology 128 379ndash391

Williamson G Rhodes MJC and Parr AJ (1999) Disease prevention

and plant dietary substances In Brown DE Walton NJ (Eds) Chemicals

from plants Perspectives on plant secondary products London Imperial

College Press 251-276

Willianson EM Okpako DT and Evans EJ (1996) Selection

Preparation and Pharmacological evaluation of plant material England John

Wiley PI

Wink M (1999) Functions of plant secondary metabolites and their

xploitation in Biotechnology CRC Press 3-9

Wiseman H and Halliwell B (1996) Damage to DNA by reactive oxygen

and nitrogen species role in inflammatory disease and progression to cancer

Biochem J 313 (Pt 1) 17-29

Wiwianitkit V (2001) High serum alkaline phosphatise level a study in

181 Thai adult hospitalized patients BMC family practice 2 2

Wolf PL (1999) Biochemical diagnosis of liver disease Indian J Clin

Biochem 14 59

Wong CC Li HB Cheng KW and Chen FA (2006) Systematic

survey of antioxidant activity of 30 Chinese medicinal plants using the ferric

reducing antioxidant power assay Food Chem 97 705-711

World Health Health Organisation (2004) WHO guidelines on good

agricultural and collection practices (GACP) for medicinal plants Geneva

World Health Health Organisation 1-133

World Health Organisation (2006) Obesity and overweight Fact sheet 311

Available from httpwwwwhointmediacentrefactsheetsfs311

enprinthtml

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 57: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Wouters K van Gorp PJ Bieghs V Gijbels MJ Duimel H

Luumltjohann D Kerksiek A van Kruchten R Maeda N Staels B van

Bilsen M Shiri-Sverdlov R and Hofker MH (2008) Dietary cholesterol

rather than liver steatosis leads to hepatic inflammation in hyperlipidemic

mouse models of nonalcoholic steatohepatitis Hepatology 48 474ndash486

Wymann MP and Schneiter R (2008) Lipid signalling in disease Nat

Rev Mol Cell Biol 9 162ndash176

Yamaguchi F Saito M Ariga T Yoshimura Y and Nakazawa H

(2000) Free radical scavenging activity of garcinol from Garcinia indica

fruit rind J Agri Food Chem 48 2320ndash2325

Yamaguchi K Yang L McCall S Huang J Yu XX Pandey SK

Bhanot S Monia BP Li YX and Diehl AM (2007) Inhibiting

triglyceride synthesis improves hepatic steatosis but exacerbates liver

damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology 45 1366ndash1374

Yang H Roberts LJ Jian Shi M Chun Zhou Li Ballard BR

Richardson A and Zhong Mao Guo Z (2004) Retardation of

atherosclerosis by overexpression of catalase or both CuZn-superoxide

dismutase and catalase in mice lacking apolipoprotein E Circ Res 95

1075ndash1081

Yang JS Lee SJ Park HW and Cha YS (2006) Effect of genistein

with carnitine administration on lipid parameters and obesity in C57Bl6J

mice fed a high-fat diet Journal of Medicinal Food 9 459ndash467

Yang RL Li W Shi YH and Le GW (2008) Lipoic acid prevents

high-fat dietndashinduced dyslipidaemia and oxidative stress A microarray

analysis Nutrition 24 582ndash588

Yang S Zhu H Li Y Lin H Gabrielson K Trush MA and Diehl

AM (2000) Mitochondrial adaptations to obesity-related oxidant stress

Arch Biochem Biophys 378 259-268

Yannerelli GG Gallego SM and Tamaro ML (2006) Effect of UV-B

radiation on the activity and isoforms of enzymes with peroxidise activity in

sunflower cotyledons Environ Exp Bot 56 174-181

Yao D Shi W Gou Y Zhou X Yee Aw T Zhou Y and Liu Z

(2005) Fatty acid-mediated intracellular iron translocation a synergistic

mechanism of oxidative injury Free Radic Biol Med 39(10) 1385ndash1398

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 58: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Yao ZM and Vance DE (1990) Reduction in VLDL but not HDL in

plasma of rats deficient in choline Biochem Cell Biol 68 552-558

Yen GC and Chen HY (1995) Antioxidant activity of various tea

extracts in relation to their antimutagenicity J Agr Food Chem 43 27-32

You M Considine RV Leone TC Kelly DP and Crabb DW (2005)

Role of adiponectin in the protective action of dietary saturated fat against

alcoholic fatty liver in mice Hepatology 42 568ndash577

Younes M (1981) Inhibitory action of some flavonoids on enhanced

spontaneous lipid peroxidation following glutathione depletion Plant Med

43 240-245

Yu L Haley S Perret J Harris M Wilson J and Qian M (2002) Free

radical scavenging properties of wheat extracts J Agri Food Chem 50

1619ndash1624

Yun SN Moon SJ Ko SK Im BO and Chung SH (2004) Wild

ginseng prevents the onset of high-fat diet induced hyperglycemia and

obesity in ICR mice Arch Pham Res 27 790ndash6

Zak B (1954) Cholesterol Methodologies A review Clin Chem 23 1201

Zhai S Dai R Friedman FK and Vestal RE (1998) Drug Metab

Dispos 26 989

Zhang HM Chen SW Zhang LS and Feng XF (2008) The effects of

soy isoflavone on insulin sensitivity and adipocytokines in insulin resistant

rats administered with high-fat diet Nat Prod Res 22 1637ndash1649

Zhang Z Apse K Pang J and Stanton RC (2000) High glucose inhibits

glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells J

Biol Chem 275 40042-40047

Zhao B (2009) Natural antioxidants protect neurons in Alzheimerlsquos disease

and Parkinsonlsquos disease Neurochem Res 34 630ndash8

Zheng S Hoos L Cook J Tetzloff G Harry DJ and Van Heek M

(2008) Ezetimibe improves high fat and cholesterol diet-induced non-

alcoholic fatty liver disease Vascular Health and Risk Management 4 235ndash

241

Zhu X Zhang W Pang X Wang J Zhao J and Qu W (2011)

Hypolipidaemic effect of n-butanol extract from Asparagus officinalis L in

mice fed a high-fat diet Phytotherapy Research 31 doi101002ptr3380

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702

Page 59: BIBLIOGRAPHY - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/17409/11/12... · 2015-12-04 · BIBLIOGRAPHY Aarsland, A. and Wolfe, R.R. (1998). Hepatic secretion of VLDL fatty

Zimmerman H J and Seeff L B (1970) Enzymes in hepatic disease In E

L Goodly (Ed) Diagnostic Enzymology (pp 1ndash38) Philadelphia USA

Lea amp Febiger

Zimmet P Shaw J and Alberti KG (2003) Preventing Type 2 Diabetes

and the Dysmetabolic Syndrome in the Real World a Realistic View Diabet

Med 20 693-702