You want a flexible and multi-usable GC or GCMS

system with increased application range and

detection limits!?

Who doesn’t

4th generation of the world’s most powerful inlet for Gas Chromatography

OPTIC Multimode Inlet changes your GC or GCMS into a flexible and multi-

usable system with increased application range and detection limits

One Inlet, More Analytical Options

OPTIC Inlet is much more than any other Inlet

Compatible with most GC’s

Your GCMS would be able to handle:

Cold and Hot Split/Splitless injections Pyrolysis (liquid and solid samples)

Large Volume Injections In-liner derivatisation LC-GC coupling possibility Headspace CryoFocusing on the column Thermal Desorbtion On-Column injections Automatic liner exchange

Direct heating technologyLow thermal mass

Septum or Merlin Seal

Septum purge lineCarrier line

Split line

High power

O-ring

Liner I.D. = 3.4mmOven wall

Cooling by Air, CO2, LN2

computer modeled temp. profile Max temp.: 600˚CMax ramp : 60˚C/sec

Thermocouple

Solvent Monitor

patented

Benefits of OPTIC Inlet

Real Septum Purge flow

Different septa ca be used: Plug typeDisk typeMerlin Microseal ™

Metal column ferrule can be used

Benefits of OPTIC Inlet

Low thermal mass >:High temperatures (up to 600°C)Fast ramp rates (up to 60°C/sec)Fast cool down time

Relatively large liner diameter (3.4 mm i.d.) >:150µl At-Once LVIDirect Thermal Desorbtion (DTD)Difficult Matrix Introduction (DMI)In-Liner derivatisationSolid and Liquid sample Pyrolysis

Best temperature profile >: good transfer of high molecular components

Temperature profiles

No Cold SpotGood for high molecular components

No discrimination

No evaporate from the syringe needle

More control over the true injected volume

Less thermal degradation (Less problems with thermally labile compounds degrade due to the thermal stress upon injection)

Better reproducibility with SPME

Very good reproducibility, also using CombiPAL

Benefits of cold injections

Cold injection versus hot injection

Hot injection

Cold injection

Performance Hot versus Cold injection

Autosampler: AOC 20i, GC-MS: QP 2010, Injector: OPTIC 3, Injection volume: 1 µl, Alkane mix: 0.5 µg/ml

Constant 320

Constant 250

Programmed 50 -> 320

Inlet temp.

Benefits of Large Volume Injection

Sample vol 1000ml 10ml 10ml

Elution vol. 2000µl 2000µl 200µl

Mass in 1µl 5pg 0.05pg 0.5pg

Injection vol. 1µl 100µl 100µl

Mass injected 5pg 5pg 50pg

Less sample and solvent is needed and

finally more is arrived at the detector.

Less sample and solvent is needed and

finally more is arrived at the detector.

LVI; Why so good with OPTIC ?

(s)10 20 30 40 50

30 oC

15

0

-15

Temp.In the liner

C5

C6

EtOAcMeOH

Good evaporate cooling effect because inlet body has a very low thermal mass

LVI Solvent Vent Monitor Function in OPTIC

Sensor Output

Time

Inject Vent valve closes

Sensor in split lineSensor in split line (standard available)(standard available)

Difficult Matrix Introduction (DMI) Raw sample or dirty extract is put into micro vial and placed directly into liner

In-injector thermal desorption or pyrolysis of liquid or solid samples

What is Difficult Matrix Introduction (DMI)?

d)

OPTIC Injector

e) Carrier In

Split Flow

Column Flow

Transport liner with sample into OPTIC inlet

Seal and purge the inlet. Apply selective exclusion principle for the analysis:

First temperature increased to just below BP of solvent

Solvent is vented through split line

Temperature and pressure ramped up to achieve selective transfer Dispose microvial after analysis, clean and re-use liner

DMI step by step:DMI step by step:

What is Difficult Matrix Introduction (DMI)?

Pyrolysis Liquid

T (°C)

t (min)

injection solventelimination

pyrolysis600

40

0 1 5

Liquid injection: simple to automate pyrolysis

Sample inlet

Vapour outlet - Temperature program to 600°C- Fast ramp rate (60°C/sec)

Pyrolysis Solid

- Sample in micro vial- Fast ramp rate (60°C/sec)- Temperature program to 600°C- Multi-Shot Pyrolysis possible- Evolved Gas Analysis (EGA) possible

On-Column solution

No press fit

No liner

No modification to OPTIC Inlet

Easy installation Real On-Column New type Merlin Microseal

can be used

CryoTrap Option

Different ramp rates for same component.

60°C/sec

30°C/sec

10°C/sec

Cryogenic cold trapping is frequently used for narrowing the chromatographic band and improving the detection limit.

OPTIC-4 Cryotrap is the fastest heating trap > resulting in sharp peaks

ATAS GL – Thermal Desoption Solution (TDS)

Main points:Main points:- Direct heatingDirect heating- Trapping on the column (one desorption from liner to column)Trapping on the column (one desorption from liner to column)- No dead volume No dead volume - Real septum purgeReal septum purge- Real Splitless transfer from sample to columnReal Splitless transfer from sample to column

LINERS

Fritted liner, frit on 15 mm

liner for split injections (single necked)

Empty liner for splitless injections

Baffled splitless liner

Fritted liner on 20 mm with single taper

“A” type packed liner for large volume injections

“8270” sintered liner for large volume injections

Sintered glass liner with taper

LINEX DMI Liner

DMI Liner Insert (micro vial)

OPTIC Injection Modes

Combined TD / Pyrolysis Injection port reactor Micro Headspace / Micro vial SPME-GC SPE-GC TCT-GC GPC-GC LC-GC Comprehensive LC x GC Automatically changing liners

Hot split injection Hot splitless injection Cold split injection Cold splitless injection On-column injection Large Volume Injection Gas enrichment Direct thermal desorption Pyrolysis (in liner) Headspace

www.glsciences.eu

For more information