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omega-3 fatty acids linkedto maintaining overallgood health*

The positive benefits of fish consumptioncontinues to be validated by researchers andscientists worldwide. While fish serves as agreat source of high quality protein, thereare also numerous positive health supporting

benefits. Fish is a tremendous source of healthy fats commonly known as Omega-3 Fatty Acids. Studies conducted over thelast decade continue to demonstrate theimportance of consuming adequate amountsof Omega-3 Fats. It is clear, these goodfats are a major contributor to sustainingoverall good health. Most importantly, thesefats are a key factor in supporting optimalcardiovascular health. They also helpmaintain the proper function of ourbrain, joints, skin, and each and every cellthroughout our body.*

healthier cardiovascularfunction

The relationship between cardiovascularhealth and Omega-3 Fatty Acidshas been researched extensively. DHA

(Docosahexaenoic Acid) and EPA(Eicosapentaenoic Acid), both powerfulOmega-3 Acids from fish oil, are also foundin high levels in heart tissue. (1) Studiesreveal a correlation between these high levelsof DHA/EPA in heart tissue and healthiercardiovascular function.

high levels of dha and ePasuPPort cardiovascularhealth*

High levels of DHA/EPA in heart tissuemirrors the concentration found in redblood cells. Those with the highest levelsof DHA/EPA in the blood tend to havehealthier cardiovascular function than thosewith lower levels. One such study followed94 healthy men, without any evidence of prior cardiovascular disease, for a period of up to 17 years. Baseline measurements of the fatty acid composition of the blood weretaken at the beginning of the trial. The trial

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analysis revealed that the men with thehighest levels of Omega-3 Fatty Acids intheir blood were the least likely to suffercardiovascular problems later in life. (2)

The Benefits of fish consumption/Omega-3 intake is confirmed in another trial thatstudied women between the ages of 34 and59. This study followed 79,839 healthywomen for up to 14 years to determinethe relative risk of cardiovascular eventscompared to their dietary intake of Omega-3 Fatty Acids. The authors showed thatwomen who consumed fish at least 2 to 4times per week had a 48% lower risk of cardiovascular problems than those who

ate no fish , whereas those eating fish onceweekly had a 22% lower risk. (3)Commenting on the reasons for these results,the authors mention that Omega-3 FattyAcids affect the production of the cascadeof inflammatory prostaglandins andleukotrienes, thereby favoring theproduction of less inflammatorymediators. This may allowfor maintenance of thepliability and elasticity of arteries, promotingnormal blood flow throughout thecirculatory system. Enhancing the healthof arteries naturally promotes healthycirculation, allowing for a healthy heart andcardiovascular system. Additional researchhas confirmed that Omega-3 Oils can

directly benefit the heart by promoting themaintenance of a normal, healthy heartrhythm. (4) A healthy heart rhythm isessential for smooth, uninterrupted bloodflow and provides the basic foundation foroptimal cardiac function.

omega-3 fish oils areessential for Brain health*

Aside from being heart healthy, researchshows Omega-3 Fish Oils are also essentialfor brain health. DHA is by far the mostpredominant fatty acid in brain tissue,accounting for upwards of 40% of the totalweight of the human brain. (5) Therefore,it should come as no surprise that Omega-3 Fatty Acids play a major role in braindevelopment, cognition, mood regulationand transmission of nerve signals. A 4 yearstudy of men and women between the agesof 63-74 measured blood cell levels of fattyacids. At the end of the 4-year period, themen and women who had higher levelsof Omega-3 Fats as a component of theirblood cell membranes were best able tomaintain normal cognitive function overthis length of time.(6) Other studies havefound similar results. A

study conducted in TheNetherlands looked atthe link between fishfatty acid intake andcognitive function. Thispopulation basedstudy of over 1,600

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subjects found that individuals with higherfish and fish oil intake were on average

better able to maintain healthy memoryfunction and normal cognition. (7)

omega-3 fish oil and Positivemood

Another area where research on fish

oil is being conducted is that of moodregulation and learning ability. Studies showthat Omega-3 Fish Oils may have a profoundeffect on promoting normal mood and affect .One study examining the population of different countries reveled a correlationbetween consumption of fish and enhancedmood within the population. (8) A clinicaltrial conducted at Harvard Universityconfirmed the ability of fish oil supplementsto enhance mood versus no effect seen in theplacebo group. (9) These effects were seenwith high doses of fish oil. Consumptionof fish and supplementation with fish oil inpromoting optimal cognitive function iscertainly well indicated. Omega-3 fatty acidsplay vastly important roles in maintainingexcellent neural health.

Protect your Bones andjoints*

Omega-3 Fatty Acids play a large role inmaintaining the health of yet another criticalpart of the body, our bones and joints.Studies have shown that Omega-3 Oils mayhave a beneficial effect on maintaining the

structure and function of joint cartilage. Arecent laboratory study conducted on humanand animal cartilage showed that when thecartilage tissue was supplied with Omega-3 Oils a noticeable protective effect wasseen. Degradation of the human and animalcartilage in this lab experiment wasnoticeably slowed by the administration of omega-3 oils. (10) Given the research inthis area, it is widely believed that omega-3oils have a positive impact on maintaininghealthy joint function.*

New research alsolinks Omega-3 oils tosustaining the healthand structure of ourbones.* Studies showthat the makeup of fats, consumed in ourdiets, has an impacton the strength of our

bones.

Om -3 F sh O Pow f S ppo s:

Heart/CardiOvaSCular HealtH*

Brain HealtH*

MeMOry and COnCentratiOn*

HealtHy triglyCeride levelS*

HealtHier Wrinkle Free Skin*

Cellular HealtH*

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omega-3 fish oils suPPortcellular health*

Omega-3 Oils derived from fish have thepotential to improve overall health throughtheir interactions with cells throughoutthe body.* Cell membranes are composedof phospholipids, or fats, that can haveeffects on membrane fluidity and cell-to-cellcommunication. Immune function, toxinremoval and energy production all occurat the cellular level. The composition of phospholipid membranes is a directreflection of the types of fats we eat. Somecomponents of these membranes includecholesterol and various other fats, includingomega-3 and omega-6 oils. A highaccumulation of certain fats can bog downthe vital processes of cellular communicationand processing of toxins. Omega-3 fats are

preferentially incorporated into the cellmembranes because they can increase theefficiency and fluidity of the cells, therebyallowing them to perform their various tasks.A deficiency of omega-3 oils in the dietcauses the operation of these cells to bogdown. A number of studies have shownthat supplemental omega-3 oils becomeincorporated into various cellularmembranes by displacing other less

desirable fats and cholesterol molecules.(11) By affecting these important functions,supplementation of omega-3 oils can supportcellular health and communication.*

maintain and enhance skinhealth*

Omega-3 oils also help maintain andenhance the health of our skin.* Theincorporation of these fats into the epidermiscan result in improved look and feel of skin tissue. (12) In vitro research on variouslines of skin cells shows that exposure toEPA and DHA confers possible protectionagainst some forms of ultraviolet radiation,maintaining the skins healthy resistanceagainst potentially harmful UV damage. (13)Some trials have also shown that Omega-3 Fatty Acid supplementation is able topreserve the normal proliferation rate of skin cells (14), which makes it useful inmaintaining supple, healthy and vibrant skin.

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the benefits of fish oilomega-3 research sPotlight june 2007, vol 1

summaryThe benefits of DHA and EPA-rich fish

oil are numerous. Science continues to affirmthat these Omega-3 Fatty Acids have thepotential to positively influence many organsand tissues. By properly supplementing ahealthy diet with Omega-3 Oils from fish,one can support the optimal functioning of the heart, brain, bones, joints, skin and justabout every cell in the body.*

References 1) Harris, WS, et al. Omega-3 fatty acids in cardiac

biopsies from heart transplantation patients: correlationwith erythrocytes and response to supplementation.Circulation, Vol. 110, September 21, 2004, pp. 1645-49

2) Albert, CM, et al. Blood levels of long-chain n-3 fattyacids and the risk of sudden death. N Engl J Med 2002;346:1113-8.

3) Iso, H, et al. Intake of fish and omega-3 fatty acids and riskof stroke in women. JAMA 2001;285:304-312.

4) Lemaitre, RN, et al. n-3 polyunsaturated fatty acids, fatalischemic heart disease, and nonfatal myocardial infarctionin older adults: the Cardiovascular Health Study. American

Journal of Clinical Nutrition, Vol. 77, February 2003, pp.319-25

5) Singh M. Essential fatty acids, DHA and human brain.Indian J Pediatr. 2005 Mar;72(3):239-42.

6) Heude B, Ducimetiere P, Berr C. Cognitive decline and fattyacid composition of erythrocyte membranesThe EVAStudy. Am J Clin Nutr. 2003 Apr;77(4):803-8.

7) Kalmijn S, et al. Dietary intake of fatty acids and fish inrelation to cognitive performance at middle age. Neurology.2004 Jan 27;62(2):275-80.

8) Hibbeln, Joseph R. Fish consumption and majordepression. The Lancet, Vol. 351, April 18, 1998, p. 1213(correspondence)

9) Kaufman, Marc (1999), Fish oil may aid against manicdepression, The Washington Post, 27 Apr, Healthsection.

10) Curtis CL, et al. Effects of n-3 fatty acids on cartilagemetabolism. Proc Nutr Soc. 2002 Aug;61(3):381-9.

11) Hashimoto, M, et al. Effects of eicosapentaenoic acid anddocosahexaenoic acid on plasma membranefluidity of aortic endothelial cells. Lipids. 1999; 34(12):1297-1304.

12) Ziboh VA, et al. Metabolism of polyunsaturated fatty acidsby skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am JClin Nutr. 2000 Jan;71(1 Suppl):361S-6S.

13) Storey A, et al. Eicosapentaenoic acid anddocosahexaenoic acid reduce UVB- and TNF-alpha-inducedIL-8 secretion in keratinocytes and UVB-induced IL-8 infibroblasts. J Invest Dermatol. 2005 Jan;124(1):248-55.

14) Mayser P, et al. Omega-3 fatty acid-based lipidinfusion in patients with chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, multicenter trial. J Am Acad Dermatol. 1998Apr;38(4):539-47

tOP 10 FiSH Oil BeneFitS

1. Fish oils comprehensively support healthyheart and cardiovascular function*

2. Fish oils enhance the structure andfunction of cellular membranes*

3. EPA and DHA promote healthy braindevelopment*

4. EPA and DHA support healthy cognitivefunction and enable efficient cell-to-cellfunction*

5. Fish oils support healthy circulation*6. EPA and DHA may enhance healthy

vision by promoting normal retinalfunction*

7. EPA and DHA enhance free radicalscavenging in tissues and organs*

8. Omega-3 fatty acids enhance the functionof complex signaling pathways in thehuman body*

9. Omega-3 fatty acids enhance the cellularuptake of vital nutrients*

10. EPA and DHA promote vibrant andyouthful skin*

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any

6Purity Products

the benefits of fish oilomega-3 research sPotlight june 2007, vol 1

The research is in and it is clear thatsupplementing your diet with Omega-3 Fish Oilsis crucial in maintaining overall good health.*Numerous studies conclude that Omega-3 FishOils can have a positive impact on the optimal

heart*

brain*

bones*

joints*

skin*

cells*

200 t m d P w, ny 11803O l : 1-800-281-7781

C s om C : 1-888-769-7873