-BemlieseTM · 2019. 10. 29. · ‘BemlieseTM’ is a 100% cupro nonwoven sheet with a variety of...
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‘Bemliese TM ’ is a 100% cupro nonwoven sheet with a variety of functions, such as high absorption, high adhesion and high transparency. Bemlise TM is incorporated in a wide range of products, including medical, for over 40 years. Offers excellent performance beyond excellent absorbent capacity ‘CMC-Bemliese TM ’ ‘CMC-Bemliese TM ’, A Carboxymethyl Cellulose Nonwoven fabric ‘Bemliese TM ’ The world’s only cellulosic continuous filament nonwoven sheet Customizable ‘CMC-Bemliese TM ’ DRY WET High Wet Strength Type Powerful ‘Mix & Match’ platform for the Next-Gen wound care products Property Products High Solubility CA40A High Wet Strength BA40C, BB40C, BC40C Customization is available if you need. For example… 1. Lamination (ex. 2, 3, 5 layer) 2. Combination with foam
Transcript of -BemlieseTM · 2019. 10. 29. · ‘BemlieseTM’ is a 100% cupro nonwoven sheet with a variety of...
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‘BemlieseTM’ is a 100% cupro nonwoven sheet with a variety of functions, such as high absorption, high adhesion and high transparency. BemliseTM is incorporated in a wide range of products, including medical, for over 40 years.
Offers excellent performance beyond excellent absorbent capacity
‘CMC-BemlieseTM’
‘CMC-BemlieseTM’, A Carboxymethyl Cellulose Nonwoven fabric
‘BemlieseTM’
The world’s only cellulosic continuous filament nonwoven sheet
Customizable ‘CMC-BemlieseTM’
DRY
WET
High Wet Strength Type
Powerful ‘Mix & Match’ platform for the Next-Gen wound care products
Property Products
High Solubility CA40A
High Wet Strength BA40C, BB40C, BC40C
Customization is available if you need. For example…1. Lamination (ex. 2, 3, 5 layer)2. Combination with foam
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✓ High absorbency : Improved exudate retention ✓ Anti-shrink properties, avoiding maceration ✓ High transparency ✓ Hemostasis properties✓ Softness and good conformability to wound shape✓ High purity : Less allergy and contamination✓ Less dead space between dressings and wound bed
Potential Contribution for Wound Care Products:
High absorbency
Key characteristics of ‘CMC-BemlieseTM (Ⅰ)’
※Test was conducted based on British Pharmacopoeia 1993 Addendum 1995 - Alginate Wound Dressings and EN-13726-1
‘CMC-BemlieseTM” is thin and excellent absorbency
CA40A : H-Solubitlity 100g/m2 DS 0.4BA40C : H-Strength 100g/m2 DS 0.4BB40C : H-Strength 80g/m2 DS 0.4BC40C : H-Strength 50g/m2 DS 0.4Aquacel : Convatec 100g/m2
※DS: Degrees of substitution
0
0.1
0.2
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0.4
0.5
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5
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CA40A BA40C BB40C BC40C Aquacel
Thickness / mm
Absorption / g/100cm2
Absorption
Thickness
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Key characteristics of ‘CMC-BemlieseTM (Ⅱ)’
Ultra-low fibers release
CMC-BemlieseTM sample type: CMC-Na, 100g/m2 , DS 0.4
(after shaking in ethanol)
Anti-shrink and Transparency
CA40A BA40C Aquacel Kaltostat
(after absorbing artificial exudate)
Absorb better, protect better and monitor better
・ Control = Without material・ CMC nonwoven sheet with different DS values（①,②,③）・ Chitosan nonwoven sheet
Control ① ② ③ Chitosan
CMC-BL
Bleeding time of rat tail treated with different hemostatic materials
‘CMC BemlieseTM’ exhibits hemostasis performance equal toor higher than other hemostatic materials
Hemostasis performance
Ohta, S., Nishiyama, T., Sakoda, M., Machioka, K., Fuke, M., Ichimura, S., Inagaki, F., Shimizu, A., Hasegawa, K., Kokubo, N., Kaneko, M., Yatomi, Y., and Ito, T.: “Development of Carboxymethyl Cellulose Non-Woven Sheets as a Novel Hemostatic Agent” Journal of Bioscience and Bioengineering, 2014, in press DOI:10.1016/j.jbiosc.2014.10.026
Continuous-filament BemlieseTM significantly reduces lint compared to many materials out of short fibers.No residue at wound bed when removing dressing
White sheet : Dry conditionRed line : Wet condition
http://dx.doi.org/10.1016/j.jbiosc.2014.10.026
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■Product concepts and potential applications
‘CMC BemlieseTM’ has been demonstrated to a number of leading clinicians.Based on their feedback, we have collated a number of product ideas:
1)Different absorption capabilities- We can provide a range of products that can deliver the optimum balance
between absorption capacity and conformability/comfort for specific wound types
2)Availability to laminate with other materials, enhancing clinical benefits
e.g. laminate with unmodified ‘BemlieseTM’ or films
3)Availability of easy stitching
e.g. pre-shaped products such as masks or glove type dressings
1)Exudating wounds – Bridging Hydrofiber® and super absorbents- Thinner than current combination products and higher absorbency than
current hydrofibers.
2)Cavity wounds- Shallow cavity wounds or deep wounds with small openings would be good
application targets due to thinness and flexibility of CMC-BemlieseTM,with less danger of overfilling
- CMC-BemlieseTM can be cut or shaped easily so that it could be used as NPWT filler
3)Post surgical wounds incl. prevention of surgical site infections- Hemostasis property of CMC-BemlieseTM helps for first 24 hours.- High transparency of CMC-BemliseTM helps wound monitoring
after 24 hours.
■Customization of ‘CMC-BemlieseTM’ during and/or after production
Product ideas of ‘CMC-BemlieseTM’
F58D019
Contact information:Ken Muraoka (Mr.)ASAHI KASEI CORPORATIONBiomaterial Business Development Dept.E-Mail : [email protected] Tel : +81-(0)3-6699-3806
