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BECODISC-
Stacked Disc Cartridges
Begerow Product LineMarkets Served Chemical, Pharmaceutical, Industrial
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Filtration
Technology
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Your Benefi t
BECODISCstacked disc cartridges
The individual cells of the BECODISC stacked disc cartridges are made up using BECO depth filter sheets.
In addition to simple hand-ling and shorter setup times, the innovative technology of stacked disc cartridges in an enclosed system offers the following benefits:
Filtrate
The principle of depth filtration BECODISC flow diagram in enclosed filter housing
Outlet Inlet
Adaption to a widevariety of filtration tasks• Wide range of types • Different sealing and plastic
materials • Different filter areas • 9-cell modules with larger
cell distance and cell spacer rail ensure very highmechanical stability when handling large quantities of solids
• Depending on the product to be filtered and the given process parameters, it may be expedient to use BECODISC stacked disc cartridges with polyamide plastic components.A wide range of gaskettypes (silicone, EPDM, Viton, FEP-coated silicone)are available for selection
Protection againstbypass effects• Precise sealing of the filter
cells through polypropylene or polyamide edge molding
• Constant final pressing • Stable unit, even during
sterilization, throughthree-part stainless steelsegmented sleeve
• Double O-ring adapter available
Performance:• Optimum flow path within
the cell throughinternal drainage plate
• Consistent/constant celldistance ensures fullutilization of the wholefilter surface
Our basic aim is to ensure high-qualitycustomer products by providing optimal depth filter media, thereby contributing to the economic efficiency and safety of the process.
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The Right BECODISC Stacked Disc Cartridge for all Filtration Tasks
BECODISC BP range
Depth filter with lowendotoxin content for phar-maceutical applications
The BP range of BECODISC stacked disc cartridges was also specially developed for pharmaceutical and bio-technology applications. The innovative production process for the depth filter sheetguarantees an endotoxin con-tent of less than 0.125 EU/ml. Quantitative analysis of endotoxins takes place at an independent laboratory and is based on a LAL test (Limulus Amebocyte Lysate), which is
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B01P
B02P
B04P
B08P
B20P
B40P
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Conditions: Δ p = 100 kPa, Medium: Water at 20 °C
BECODISC BP range
BECODISC B00P
Stacked disc cartridges with support sheets for cake filtration in thepharmaceutical industry
BECODISC B00P wasspecially developed to meet the strict requirements of the pharmaceutical industryregarding separation of resource substances and for cake filtration. A special pro-duction process for the depth filter sheet guarantees that the endotoxin content is less than 0.125 EU/ml. A filter sheet validation guide is available.
Main applications:Pharmaceutical,fine/specialty chemistry, biotechnology
BECODISC B30C
Filters containing activated carbon
The BECODISC B30C filter sheets have a high activated carbon content and therefore a high adsorption capacity. These adsorptivecharacteris-tics enable decolorization of solutions, for example. The BECODISC B30C is also very suitable for lipid removal or dechlorination.
Further details can be foundin the Technical Information1 A 2.5.5.11Main applications:Pharmaceutical,biotechnology, chemistry,fine/specialty chemistry, cosmetics
used as standard to test the depth filter sheets from the BECO PR range.
Our long-standing experience in the production of stacked disc cartridges in conjunction with the special technologyof the manufacturingprocess guarantees anefficient depth filter medium with demonstrably consistent product quality. A validation guide for depth filter sheets is avai lable providing support for the design, execution and documen tation of a validation. The application of BECODISC BP stacked disc cartridges ensures that the high quality expectations for themanu facturing of pharma-ceutical and biotech products are met.
Further details can be foundin the Technical Information1 A 2.5.5.9Main applications:Pharmaceutical, fine/specialty chemistry, biotechnology
In compliance with
pharmaceutical processes In compliance with
pharmaceutical processes
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The Right BECODISC Stacked Disc Cartridge for all Filtration Tasks
BECODISC BS range
Depth filter for standard applications
Standard BECODISC stacked disc cartridges are used in the chemical and cosmetics industry. This stacked disc cartridge range is also used successfully in certainsections of the pharma-ceutical and biotechnology industry (e.g. process water). Numerous grades covering a wide retention range enable precise adaptation to the respective task within the required separation range.
Further details can be foundin the Technical Information1 A 2.5.5.8Main applications: Chemistry, cos me tics, pharmaceutical, biotechnology
BECODISC BT range
Depth filters for filtration of highly viscous liquids
The BECODISC stacked disc cartridges of the BT range are optimized for the filtration of liquids with high particle contents and highly viscous liquids. The BT range ofstacked disc cartridges is therefore mainly used in the chemical and cosmetics industry.
Further details can be foundin the Technical Information1 A 2.5.5.12Main applications: Chemistry, cosmetics, pharmaceutical, biotechnology
BECODISC B00E
Stacked disc cartridge with support sheetsfor cake filtration
The BECODISC stacked disc cartridges with support sheets B00E are particularly suitable for separation of resource substances and for cake filtration in industrial applications.
Main applications:Chemistry, cosmetics
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B15T
B20T
B25T
B30T
B27T
B40T
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30 46 60 155
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B01S
B02S
B03S
B04S
B05S
B06S
B08S
B10S
B15S
B20S
B25S
B30S
B40S
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69 84 115 185 225 270 42
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Conditions: Δ p = 100 kPa, Medium: Water at 20 °C
Without mineral components
Conditions: Δ p = 100 kPa, Medium: Water at 20 °C
BECODISC BT range BECODISC BS range
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Overview of BECODISC Stacked Disc Cartridges
From coarse filtration to microbe removal, several product ranges for various applications, production technologies and filtration tasks are available.
Our filtration specialistsrecommend carrying outpreliminary tests and will be happy to provide advice.
For laboratory or pilot plant trials our applica tion enginee-ring division provides support
for complex tasks and for se-lecting the right filter medium with the aim of achieving the optimum filtrate quality and filtration performance.
The selection of theappropriate depth filter type and filtration tech nique(cake filtration or clarification) depends on the composition of the liquid to be filtered, the application and the process parameters
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B00E
80.0 40.0 30.0 15.0 10.0 5.0 4.5 4.0 2.5 0.6 0.1
Nominal retention ratein µm
Stacked disc
cartridges with
support sheets
Stacked disc
cartridges containing
activated carbon
BECODISC stacked disc cartridges
B00E
Microbe reductionand microbe removal
Coarse, clarification, fine filtration
B00P
B30C
BS range
BP range
BT range
In compliance with
pharmaceutical processes
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Areas of Application
In the chemical industry an important task is the removal of residues and contamina-tion from raw, intermediate or finished products. Varnishes, paints, silicone products, synthetic resins, softeners, pesticides, abrasives, waxes and industrial oils offer awide range of applications.In these manufacturing processes the stacked disc cartridge often has to offer above-average chemical resistance against aggressive solvents or strong acids and caustic solutions at deman-ding temperatures, as well as high dirt holding capacity.
In fine and specialtychemistry a frequent task is the removal of un desired contamination and wasteproducts from previousprocess steps or the separa-tion of valuable metalliccatalysts, activated carbon powder or filter aids. An application example from antibiotics production is the
face and hair tonics, skin and bath oils.
In the production oftherapeutic proteins from blood plasma (e.g. albumin, immunoglobulin, clottingfactors) the main function of the depth filter medium is the economical and reliable separation of precipitates. In addition, the production process involves numerous clarification and fine filtration steps aimed at removingcontaminants such as endotoxins and protecting downstream systems from premature blocking.
In fermentativeproduction pro cesses,filtration in downstream processing is a very important process step. The depth filter has the task of reliablyremoving cells and cellfragments from fermenter broth. Typical application examples include produc - tion processes for
adsorptive separation ofdecolorization via sheetscontaining activated carbon.
High dirt holding capacityand microbe reduction withsimultaneous preservation of active ingredients plays an important role in the pro-duction of active ingredients of plant origin, which are used in the cosmetics and perfume sector and in theproduction of naturalremedies and aromas.
In the cosmetics industryan important task is theremoval of particulatecontamination and sub-stances that can lead to undesired hazing andprecipitation in the finished product. This is ensured through the applica tion of stacked disc cartridges in the processing of essential oils, alcohol-based perfumes, fragrances and aroma sub-stances, resins and terpenes, creams, shampoos and lotions,
industrial enzymes, which are used in the food anddetergent industries, for example, or for specialenzymes used in diagnostics, or for active biopharma -ceutical ingredients.
In the production ofpharmaceutical precursor, intermediate and fin ished products, depth filtration is required for pro tecting downstreammembrane filters, ultrafilters, chromatography columns and cross-flow-equipment.
Application example BECODISC stacked disc cartridges
Aftershave B08S – B40S
Activated carbon removal B25S
Alcoholic herbal extracts B08S – B02S
Alkyd resins B30S – B27T
Amino acids B10S – B25S
Antibiotics B30C
Aromas B10S – B40S
Active earth separation B15T – B27T
Dialysis concentrates B20P – B40P
Eau de Cologne B06S – B10S
Enzyme solutions B08P – B40P
B00P
Ethylene glycol B15S – B25S
Fermenter broth B01P – B40P
Photographic emulsions B06S – B20S
B00E
Face lotions B04S – B15S
Hair lotions B04S – B15S
Resin melts B25T – B27S
Hormones B02P – B20P
Human plasma products B04P, B01P, B02P
B00P
Vaccines B01P – B08P
Infusion solutions B01P – B40P
Application example BECODISC stacked disc cartridges
Insulation oils B20T – B27T
Camomile press juice B01S – B25S
Carbon catalyser B00E
Clear varnishes B20S – B27T
Cosmetic oils B10S – B15S
Boiled linseed oils B20T – B27T
Nail vanish B20T – B27T
Oil varnishes B15S – B25S
Organic solvents B08S – B40S
Plant extracts B01S – B20S
Plasma expanders B01P – B08P
Process water B01P – B40P
Ointment base B20S – B40S
B15T – B27T
Sera B01P – B40P
Silicone oils B40S – B10S
Syrup B15T – B30T
Industrial oils B15T – B20S
Tensides B10S – B27T
Vaseline B15S – B25S
Vitamin suspensions B01S – B02S
Active ingredients B08P – B40P
Cell culture media B01P – B40P
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Suitable Solutions for a Large Number of Applications
Please note that the filter type classification is only intended for guidance. The choice and suitability for the respective application must be determined through pre-trials.
Companies from a wide range of industries rely on depth filter media from Begerow Product Line
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Enclosed Filtration System BECO INTEGRA DISC
Depth filter media are used in the following different filtra-tion systems: in enclosed plate and frame filters, stacked disc cartridge housings, single sheet filters, laboratory filters, and in a range of classic plate and frame filters. These filtra-tion systems are developed by Begerow Product Line Process Technology.
Enclosed filtration systems
As an enclosed system, the pro duct line BECO INTEGRA is the alternative to classic filtration systems, wherever the protection of operating personnel and product is a priority.
BECO INTEGRA DISC
Concept and configuration BECO INTEGRA DISC areen closed filter housingsconsisting of a bottom part with three legs and a detach-able housing dome. The bottom part with inlet and outlet socket contains the centering and mounting unit for holding the stacked disc
Types:
Pharmaceutical design Stacked disc cartridge housing BECO INTEGRA DISC P meet the requirements of pharma-ceutical processes and have the following features:• TC connections according to ISO• CIP/SIP capability• Diaphragm valves and manometer• FDA-compliant gaskets
industrial design BECO INTEGRA DISC I are used for a wide rage offiltration tasks in the chemi cal industry. The industrial version was specially designed with a raised border at the bottom part for: • Clean production conditions• Difficult to handle products• Safe handling of aggressive media
cartridge with a flat adapter or double O-ring adapter. The connection between the flat bottom part and the housing dome is realized through a quick closure devise in V-ring design or through clamp screws.
Modules and types The complete system con-sisting of BECODISC stacked disc cartridges and BECOINTEGRA DISC housings should be indi vidually con-figured for every application.Stacked disc cartridge housings are available ina variety of sizes, designsand types.
BECO INTEGRA DISC 12" und 16"
Stacked disc cartridge housing for holding 1 – 4 stacked disc cartridges with filter areas from 0.59 m2 (6.35 ft2) up to a maximum of 14,8 m2 (159.31 ft2).
BECO INTEGRA DISC 16"/...
Multi-column stacked disc car tridge housing for holding up to six columns, each with four stacked disc cartridges with filter areas from 11.1 m2 (119.5 ft2) up to a maximum 88.8 m2 (955.84 ft2). The stacked disc car tridge hous ing type is determined by the respective application.
Begerow Product Line offers a wide range of components and devices, including com-plex fi l tration systems.
Using these resources, the engineer ing specialists from process technology develop opti mized solu tions for each customer. They offer com-petent and practical support from the preparation of the requirements profile and its imple men tation in practice, from delivery documentation to customer staff training.
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We are committed to provid-ing consistently high product quality, in order to meet the quality requirements of our customers. As part of the manufacturing process, the depth filter medium helps to ensure safe, reproducible, and economical results for our customers.
We meet this responsibility by ensuring that our products comply with national and interna tional quality standards such as the German LFGB1), the FDA2) guide lines, the hygiene guidelines according to HACCP3). We have been complying with the require-ments of DIN EN ISO 9001 and updated versions since 1993. Moreover, we make ourselves available for regular audits through external, independent institutes and customers.
• The depth filter sheets of BECODISC stacked disc cartridges are certified for hot filtration applications, based on LFGB (German Food, Consumer Goods and Feed Code) according to recommendation XXXVI/I of the Plastics Commission of BfR4) (Federal Institute for Risk Assessment).
• The silicone seals of BECODISC stacked disc cartridges comply with BfR recommendation XV for silicone.
• The plastic components of BECODISC stacked disc cartridges (polypropylene) comply with Directive 2002/72/EC and amend-ments relating to materials and objects made of plastic (excluding gaskets).
BECODISC stacked disccartridges meet the require-ments of Commission
Regulation (EC) No 2023/2006 on good manu facturing practice for materials and articles in-tended to be exposed to food.
All materials used inBECODISC stacked disc car-tridges meet the requirements of FDA, as specified in the Code of Federal Regulation. Specifically:• the depth filter sheets meet
the requirements according to 21 CFR § 177.2260.
• plastic components (polypropylene) meet the requirements according to 21 CFR § 177.1520;
• the sealing materials meet the requirements according to 21 CFR § 177.2600.
The procedures fordevelopment, production, and testing of our products are based on more than 80-year-old experience with depth filter media. Staff at all levels of our company contribute to ensuring and continuously im provingthe quality of our products and services.
BECO depth filters are listed with the FDA under thefollowing master file number:
BECO depth filter sheets:• Drug Master File DMF 9926
BECODISC stacked disc cartridges:• Drug Master File DMF 15690
BECODISC stacked disc car- tridges meet the requirements of EC Regulation (EC) No 1935/2004:
Quality
1) German Food, Commodity and Feed Act2) Food and Drug Administration, USA3) Hazard Analysis of Critical Control Points4) Federal Institute of Risk Assessment
BECODISC BP range
Type Utilizeddepth fi ltersheets
Nominalretention- rate μm
Thickness
mm (in)
Ashcontent
%
Burstingstrengthwet kPa (psi)
Water throughput at Δ p = 100 kPa l m-2 min-1
Endotoxin- content1)
EU/ml
B01P PR Steril S 100 0.1 3.9 (0.15) 58.0 > 50 (> 7.3) 30 < 0.125
B02P PR Steril S 80 0.2 3.9 (0.15) 50.0 > 80 (> 11.6) 46 < 0.125
B04P PR Steril 40 0.4 3.9 (0.15) 49.0 > 50 (> 7.3) 61 < 0.125
B08P PR 12 0.8 3.9 (0.15) 50.0 > 130 (> 18.9) 175 < 0.125
B20P PR 5 2.0 3.9 (0.15) 50.0 > 60 (> 8.7) 330 < 0.125
B40P PR 1 4.0 3.9 (0.15) 48.0 > 45 (> 6.5) 2381 < 0.125
BECODISC B00P
Type Utilizeddepth fi ltersheets
Thickness
mm (in)
Ashcontent
%
Burstingstrengthwet kPa (psi)
Waterthroughput at Δ p = 100 kPa l m-2 min-1
Endotoxin- content1)
EU/ml
B00P2) PR ENDURA 3.4 (0.13) < 1.0 > 700 (< 101.5) 4290 < 0.125
BECODISC B30C
Type Utilizeddepth fi ltersheets
Thickness
mm (in)
Ashcontent
%
Burstingstrengthwet kPa (psi)
Waterthroughput at Δ p = 100 kPa l m-2 min-1
B30C ACF 07 3.8 (0.15) 15.0 > 40 (> 5.8) 1415
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Technical Data
These data are typical values for the depth filter sheet used and only serve as guidance for the selection of stackeddisc cartridges.
1) The endotoxin content at the depth filter sheet should be determined after rinsing with 50 l/m2/13.2 gal/m2 WFI2) Without mineral components
BECODISC BT range
Type Utilizeddepth fi ltersheets
Nominalretention- rate μm
Thickness
mm (in)
Ashcontent
%
Burstingstrengthwet kPa (psi)
Water throughput at Δ p = 100 kPa l m-2 min-1
B15T CP07S 15.0 3.6 (0.14) 35.0 > 110 (> 16.0) 4290 B20T CP03S 20.0 3.7 (0.15) 35.0 > 90 (> 13.1) 7140 B25T CP02S 25.0 3.3 (0.13) 17.0 > 90 (> 13.1) 9520 B30T CP01S 30.0 4.6 (0.18) 16.0 > 100 (> 14.5) 12500 B27T2) CP2KS 27.0 2.9 (0.11) < 1.0 > 150 (> 21.8) 9760 B40T2) CP1KS 40.0 4.3 (0.17) < 1.0 > 150 (> 21.8) 22620
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BECODISC B00E
Type Utilizeddepth fi ltersheets
Thickness
mm (in]
Ashcontent
%
Burstingstrengthwet kPa (psi)
Water throughput at Δ p = 100 kPa l m-2 min-1
B00E2) ENDURA 3.4 (0.13) < 1.0 > 700 (> 101.5) 4290
These data are typical values for the depth filter sheet used and only serve as guidance for the selection of stacked disc cartridges.
BECODISC BS range
Type Utilizeddepth fi ltersheets
Nominalretention- rate μm
Thickness
mm (in)
Ashcontent
%
Burstingstrengthwet kPa (psi)
Water throughput at Δ p = 100 kPa l m-2 min-1
B01S Steril S 100 0.1 3.9 (0.15) 58.0 > 50 (> 7.3) 30 B02S Steril S 80 0.2 3.9 (0.15) 50.0 > 80 (> 11.6) 46 B03S Steril 60 0.3 3.9 (0.15) 50.0 > 50 (> 7.3) 60 B04S Steril 40 0.4 3.9 (0.15) 49.0 > 50 (> 7.3) 69 B05S SD 30 0.5 3.9 (0.15) 50.0 > 50 (> 7.3) 84 B06S KDS 15 0.6 3.9 (0.15) 50.0 > 50 (> 7.3) 115 B08S KDS 12 0.8 3.9 (0.15) 50.0 > 50 (> 7.3) 155 B10S KD 10 1.0 3.9 (0.15) 50.0 > 50 (> 7.3) 185 B15S KD 7 1.5 3.9 (0.15) 50.0 > 50 (> 7.3) 225 B20S KD 5 2.0 3.9 (0.15) 50.0 > 50 (> 7.3) 270 B25S KD 3 2.5 3.9 (0.15) 50.0 > 40 (> 5.8) 425 B30S K 2 3.0 3.9 (0.15) 46.0 > 50 (> 7.3) 1550 B40S K 1 4.0 3.9 (0.15) 42.0 > 60 (> 8.7) 1900
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BECODISC 12" (Ø 295 mm/11.6 in)
Number of cells 16 14 9 1) 9 9 5
Overall height of flat adapter mm (in) 276 (10.9) 276 (10.9) 276 (10.9) 276 (10.9) 195 (7.7) 101.2 (4.4)
Overall height double O-ring adapter mm (in) 329 (13.0) 329 (13.0) 329 (13.0) 329 (13.0) 248 (10.0) 155 (6.1)
Filter surface area m2 (ft2)) 1.9 (20.5) 1.65 (17.8) 1.1 (11.8) 1.1 (11.8) 1.1 (11.8) 0.59 (6.4)
Protective fleece (polyester) 2) without without with without without without
Cell spacer rail without without with with without without
Approx. valuestacked disccartridge weight (dry) kg (lb)
Approx. valuestacked disccartridge weight (dry) kg (lb) 3)
4.2 12.5(9.3) (27.6)
3.5 10.3(7.7) (22.7)
2.2 6.5(4.9) (14.3)
2.2 6.5(4.9) (14.3)
2.0 6.3(4.4) (13.9)
1.1 3.5(2.4) (7.7)
Precoat volume l (gal) 4) 3.6 (0.9) 8.0 (2.1) 8.0 (2.1)
BECODISC 16" (Ø 402 mm/15.8 in)
Number of cells 16 14 91) 9 5
Overall height of flat adapter mm (in) 276 (10.9) 276 (10.9) 276 (10.9) 195 (7.7) 101.2 (4.0)
Overall height double O-ring adapter mm (in) 329 (13.0) 329 (13.0) 329 (13.0) 248 ( 10.0) 155 (6.1)
Filter surface area m2 (ft2)) 3.7 (39.8) 3.2 (34.4) 2.1 (22.6) 2.1 (22.6) 1.15 (12.4)
Protective fleece (polyester) 2) without without with without without
Cell spacer rail without without with without without
Approx. valuestacked disccartridge weight (dry) kg (lb)
Approx. valuestacked disccartridge weight (dry) kg (lb) 3)
9.1 22.8(20.1) (50.3)
7.9 19.9(17.4) (43.9)
5.5 12.7(12.1) (28.0)
5.3 12.5(11.7) (27.6)
3.1 6.9(6.8) (15.2)
Precoat volume l (gal) 4) 7.0 (1.8) 15.4 (4.1)
Confi guration
1) Special stacked disc cartridge version with cell spacer rails providing increased mechanical stability for holding filter cakes2) BECODISC B30C and C30C: design with protective fleece3) Measured with water at 20 °C/68 °F4) Calculated values (BECO depth filter sheet with 4 mm/0.16 in thickness)
Structure of Article Numbers
1) Full details for the mineral-free BECODISC stacked disc cartridges with BECOPAD and BECOPAD P depth filter sheets can be found in the corresponding brochures.
B 02 S 1 2 S F
Stacked disc cartridge types:
B = injection molded parts polypropylene
C = injection molded parts polyamide
Nominal retention rate:
here 0.2 μm
00 for support sheets
12, 17, 22, 27, 35, 45, 55 at BECOPAD (P)1)
Product range for depth filter sheets:
P = pharmaceutical range (PR range)
C = activated carbon stacked disc cartridge
S = standard range
T = CPS range
1 = BECOPAD P range1)
3 = BECOPAD range1)
Product range and version for support sheets:
P = PR ENDURA
E = ENDURA
only in combination with retention rate 00
Overall height of flat adapter/
double O-ring adapter (mm/in):
6 = 16 filter cells [276 mm (10.9 in)/329 mm (13.0 in)]
4 = 14 filter cells (276 mm (10.9 in)/329 mm (13.0 in)]
3 = 9 filter cells with fleece, with cell spacer rail
(276 mm (10.9 in)/329 mm (13.0 in)]
7 = filter cells without fleece, with cell spacer rail
(276 mm (10.9 in)/329 mm (13.0 in)]
9 = filter cells without fleece, without cell spacer rail
(195 mm (7.7 in)/248 mm (10.0 in)]
5 = 5 filter cells (101.2 mm/155 mm)
Size:
2 = 12", 295 mm/11.6 in ø
4 = 16", 402 mm/15.8 in ø
Sealant:
S = silicone
E = EPDM
V = fluoroelastomer/Viton
F = silicone/FEP coated
Adapter:
F = flat adapter
S = double O-ring-adapter
15
EN 1 A 2.5.6.1
03-2012
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© 2012 Eaton Corporation. All rights reserved. All trademarks and registered trademarks are the property of their respective owners. Printed in Germany.
For more information, please e-mailus at fi [email protected]
Visit us online at eaton.com/fi ltrationfor a complete list of Eaton’s fi ltrationproducts
All information and recommendations appearing in this brochure concerning the use ofproducts described herein are based on tests believed to be reliable. However, it is the user’sresponsibility to determine the suitability for his own use of such products. Since the actualuse by others is beyond our control, no guarantee, expressed or implied, is made by Eaton asto the effects of such use or the results to be obtained. Eaton assumes no liability arising out ofthe use by others of such products. Nor is the information herein to be construed as absolutelycomplete, since additional information may be necessary or desirable when particular orexceptional conditions or circumstances exist or because of applicable laws or governmentregulations.
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