BCC4: Plunkett on Thoracic Aortic Dissection

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Brian Plunkett Advanced Trainee in Cardiothoracic Surgery Dept Cardiothoracic Surgery, RNSH Aortic Dissection Bedside Critical Care, Cairns, 2013

description

Budding cardiothoracic intensivists will enjoy this talk by Brian Plunkett on thoracic aortic dissection given at Bedside Critical Care Conference 4. For the audio access and similar talks, head over to intensivecarenetwork.com

Transcript of BCC4: Plunkett on Thoracic Aortic Dissection

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Brian PlunkettAdvanced Trainee in Cardiothoracic Surgery

Dept Cardiothoracic Surgery, RNSH

Aortic Dissection

Bedside Critical Care, Cairns, 2013

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Pathogenesis

Entry tears: Asc Ao 60%, Arch 10%, Descending 30%

Intimal tear, propagates in medial layer antegrade (90%)

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Pathogenesis: Risk Factors

A: age, atherosclerosis, aneurysm B: bicuspid aortic valve (fibrillin def.)

blood pressure (hypertension)

C: connective tissue disorder Marfan’s, Ehlers-Danlos, Lewy Deitz

D: degenerative cystic medial degeneration

E: trauma, iatrogenic, surgery, pregnancy

2-3 / 100,000 age 60-70 M:F >2:1

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Pathogenesis

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Pathogenesis

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Pathogenesis

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Pathogenesis: Acute Aortic Syndrome

Penetrating atherosclerotic ulcer & acute intramural haematoma

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Classification

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Presentation Pain – ‘ripping’, ‘tearing’

- may radiate to back Symptoms of organ malperfusion

- MI, stroke, mesenteric ischaemia Dyspnoea

-AR, tamponade, haemothorax Hypo or hypertension, BP differential AR murmur Absent distal pulses

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Diagnosis

60% 95%

98%99%

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Management - MedicalMedical & drug history, clinical exam: document neurology and pulses

Normalise the blood pressure (care with AR)Defer intubation until theatre if possible

Opioids, invasive monitoringPray they haven’t given aspirin, clopidogrel, clexane

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Type A Essentially all patients considered (age, met’s) Resect primary tear, stabilize aortic wall End organ protection, correct malperfusion Prevent life threatening rupture, tamponade, AR,

coronary dissection

Type B Reserved for ‘complicated’ cases

Rupture or impending rupture (pain, eff.) Threatened or evident malperfusion Sometimes controversial

Surgery

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Surgery

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Surgery

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Approaches to the Ascending Aorta

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Cerebral perfusion strategies

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Approaches to the Aortic Root

Bentall’s

David & Yacoub

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De-branching and replacing ascending aorta

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De-branching and stenting the arch

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Stenting Type B dissections

10% 30 day medical mortality, 25% with surgery, paraplegia 15%+

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Key points

Goals

• early diagnosis, initiate therapy before confirmation

• atypical NSTEMI – think AoD before anticoagulation

• early path to definitive therapy

• the right operation for the right patient

Pitfalls

• misdiagnosis: MI, stroke, ischaemic limb embolism

• delayed care

• failure to control, or adequately control HR & BP

- includes postoperatively!

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