Basics of Mechanical Ventilators

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    Biomedical Engineer Today

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    Overview of topics1. Settings

    2. Modes

    3. Advantages and disadvantages between modes4. Guidelines in the initiation of mechanical ventilation

    5. Common trouble shooting examples withmechanical ventilation

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    Settings1. Trigger mode and sensitivity

    2. Respiratory rate

    3. Tidal Volume4. Positive end-expiratory pressure (PEEP)

    5. Flow rate

    6. Inspiratory time

    7. Fraction of inspired oxygen

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    Tidal Volume The tidal volume is the amount of air delivered with

    each breath. The appropriate initial tidal volumedepends on numerous factors, most notably thedisease for which the patient requires mechanicalventilation.

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    Positive End-Expiratory Pressure

    (PEEP)Applied PEEP is generally added to mitigate end-

    expiratory alveolar collapse. A typical initial appliedPEEP is 5 cmH2O. However, up to 20 cmH2O may beused in patients undergoing low tidal volumeventilation for acute respiratory distress syndrome(ARDS)

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    Flow Rate The peak flow rate is the maximum flow delivered by

    the ventilator during inspiration. Peak flow rates of 60L per minute may be sufficient, although higher ratesare frequently necessary. An insufficient peak flow rateis characterized by dyspnea, spuriously low peakinspiratory pressures, and scalloping of the inspiratorypressure tracing

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    Inspiratory Time: Expiratory Time

    Relationship (I:E Ratio) During spontaneous breathing, the normal I:E ratio is

    1:2, indicating that for normal patients the exhalationtime is about twice as long as inhalation time.

    If exhalation time is too short breath stacking occursresulting in an increase in end-expiratory pressure alsocalled auto-PEEP.

    Depending on the disease process, such as in ARDS,the I:E ratio can be changed to improve ventilation

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    Modes of Ventilation: The BasicsAssist-Control Ventilation Volume Control

    Assist-Control Ventilation Pressure Control

    Pressure Support Ventilation Synchronized Intermittent Mandatory Ventilation

    Volume Control

    Synchronized Intermittent Mandatory Ventilation

    Pressure Control

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    Assist Control VentilationA set tidal volume (if set to volume control) or a set

    pressure and time (if set to pressure control) isdelivered at a minimum rate

    Additional ventilator breaths are given if triggered bythe patient

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    Pressure Support Ventilation The patient controls the respiratory rate and exerts a

    major influence on the duration of inspiration,inspiratory flow rate and tidal volume

    The model provides pressure support to overcome theincreased work of breathing imposed by the diseaseprocess, the endotracheal tube, the inspiratory valvesand other mechanical aspects of ventilatory support.

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    Synchronized Intermittent

    Mandatory Ventilation Breaths are given are given at a set minimal rate, however if

    the patient chooses to breath over the set rate no additionalsupport is given

    One advantage of SIMV is that it allows patients to assumea portion of their ventilatory drive

    SIMV is usually associated with greater work of breathingthan AC ventilation and therefore is less frequently used asthe initial ventilator mode

    Like AC, SIMV can deliver set tidal volumes (volumecontrol) or a set pressure and time (pressure control)

    Negative inspiratory pressure generated by spontaneousbreathing leads to increased venous return, whichtheoretically may help cardiac output and function

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    Advantages of Each ModeMode Advantages

    Assist Control Ventilation (AC) Reduced work of breathing comparedto spontaneous breathing

    AC Volume Ventilation Guarantees delivery of set tidal volume

    AC Pressure Control Ventilation Allows limitation of peak inspiratorypressures

    Pressure Support Ventilation (PSV) Patient comfort, improved patientventilator interaction

    Synchronized Intermittent MandatoryVentilation (SIMV)

    Less interference with normalcardiovascular function

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    Disadvantages of Each ModeMode Disadvantages

    Assist Control Ventilation (AC) Potential adverse hemodynamic effects,may lead to inappropriatehyperventilation

    AC Volume Ventilation May lead to excessive inspiratorypressures

    AC Pressure Control Ventilation Potential hyper- or hypoventilationwith lung resistance/compliancechanges

    Pressure Support Ventilation (PSV) Apnea alarm is only back-up, variablepatient tolerance

    Synchronized Intermittent MandatoryVentilation (SIMV)

    Increased work of breathing comparedto AC

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    Guidelines in the Initiation of

    Mechanical Ventilation Primary goals of mechanical ventilation are adequate

    oxygenation/ventilation, reduced work of breathing,synchrony of vent and patient, and avoidance of highpeak pressures

    Set initial FIO2 on the high side, you can always titratedown

    Initial tidal volumes should be 8-10ml/kg, dependingon patients body habitus. If patient is in ARDSconsider tidal volumes between 5-8ml/kg withincrease in PEEP

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    Guidelines in the Initiation of

    Mechanical Ventilation Use PEEP in diffuse lung injury and ARDS to support

    oxygenation and reduce FIO2

    Avoid choosing ventilator settings that limit expiratorytime and cause or worsen auto PEEP

    When facing poor oxygenation, inadequateventilation, or high peak pressures due to intolerance

    of ventilator settings consider sedation, analgesia orneuromuscular blockage

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    Trouble Shooting the Vent Common problems

    High peak pressures

    Patient with COPD Ventilator synchrony

    ARDS

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    Trouble Shooting the Vent If peak pressures are increasing:

    Check plateau pressures by allowing for an inspiratorypause (this gives you the pressure in the lung itself

    without the addition of resistance)

    If peak pressures are high and plateau pressures are lowthen you have an obstruction

    If both peak pressures and plateau pressures are highthen you have a lung compliance issue

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    Trouble Shooting the Vent If you have a patient with history of COPD/asthma

    with worsening oxygen saturation and increasinghypercapnia differential includes: Given the nature of the disease process, patients have difficultly

    with expiration (blowing off all the tidal volume)

    Must be concern with breath stacking or auto- PEEP

    Management options include:

    Decrease respiratory rate Decrease tidal volume

    Adjust flow rate for quickerinspiratory rate

    Increase sedation

    Adjust I:E ratio

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    Trouble Shooting the Vent Increase in patient agitation and dis-synchrony on the

    ventilator:

    Could be secondary to overall discomfort

    Increase sedation

    Could be secondary to feelings of air hunger

    Options include increasing tidal volume, increasing flow rate,adjusting I:E ratio, increasing sedation

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    Trouble shooting the vent If you are concern for acute respiratory distress

    syndrome (ARDS)

    Correlate clinically with HPI and radiologic findings ofdiffuse patchy infiltrate on CXR

    Obtain a PaO2/FiO2 ratio (if < 200 likely ARDS)

    Begin ARDSnet protocol:

    Low tidal volumes

    Increase PEEP rather than FiO2

    Consider increasing sedation to promote synchrony withventilator