Basic Bio Statistics Module2
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Transcript of Basic Bio Statistics Module2
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ACCE
Biostatistics Training Course
Spring 2005
O. Dale Williams, MPH, PhD
Professor of Medicine and Biostatistics
University of Alabama at Birmingham
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Questions
Why are you taking this course?
What do you hope to get out of the course?
Are you concerned about the level of
mathematics that will be required?
Have you taken any statistics courses
previously?
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Course Purpose
To provide non-biostatisticians with the ability to
understand and utilize basic biostatistical conceptsand tools and to facilitate their capacity to seek and
utilize biostatistical expertise as may be required
when conducting their own research or reviewingthat done by others. This course is required for all
MPH degree program students as a component of
the web-based integrated core curriculum.
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Course Objective
Student successfully completing this course should:
Understand and be able to use the basic conceptsof biostatistics;
Understand and be able to use the basic tools ofbiostatistics;
Be able to work effectively with a professionalbiostatistician on problems requiring moreadvanced concepts and tools;
Be able to read, understand and judge theappropriateness of the use of biostatisticalconcepts and tools in the basic public health
literature.
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Course Topics
Types of data, tables and graphs, frequencydistribution
Measures of central tendency and dispersion
Population versus sample, sampling distributions,
normal distribution Point estimates, confidence intervals
Hypothesis testing concepts
z-tests, t-tests Sample size determination
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Course Topics (Contd.)
Tests for proportions and variances
Analysis of variance--one-way, randomized
blocks, factorial designs
Regression and correlation
Contingency tables, chi-square tests
Multiple linear regression
Relative risk, odds ratios, logistic regression
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In order to provide a more concrete picture of what
the course will cover, we will take a brief look at a
relatively recent article in theAmerican Journal of
Public Health. To understand this article, you will
need to understand the basic concepts and many of
the basic tools of biostatistics. We will review this
article now and then come back and review it again
at the end of the course.
What We Will Cover
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Article for Review
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The game plan is for you to be able to understand,interpret and utilize appropriately the information
in articles such as this. Further, you should be able
to question whether something was properly done.
The Game Plan
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The basic strategy we will follow is to first focus on
the types of data, then examine tables and graphs and
frequency distributions. This is critical background
for understanding samples and populations, estimates
of population parameters and the fundamental
elements of hypothesis testing. We will then address
z-tests, t-tests and many of the other biostatistical
tools routinely appearing inAJPH. In fact, much of
the material will be presented in the context of
relatively recentAJPHarticles.
The Strategy