Basic Bio Statistics Module2

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    ACCE

    Biostatistics Training Course

    Spring 2005

    O. Dale Williams, MPH, PhD

    Professor of Medicine and Biostatistics

    University of Alabama at Birmingham

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    Questions

    Why are you taking this course?

    What do you hope to get out of the course?

    Are you concerned about the level of

    mathematics that will be required?

    Have you taken any statistics courses

    previously?

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    Course Purpose

    To provide non-biostatisticians with the ability to

    understand and utilize basic biostatistical conceptsand tools and to facilitate their capacity to seek and

    utilize biostatistical expertise as may be required

    when conducting their own research or reviewingthat done by others. This course is required for all

    MPH degree program students as a component of

    the web-based integrated core curriculum.

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    Course Objective

    Student successfully completing this course should:

    Understand and be able to use the basic conceptsof biostatistics;

    Understand and be able to use the basic tools ofbiostatistics;

    Be able to work effectively with a professionalbiostatistician on problems requiring moreadvanced concepts and tools;

    Be able to read, understand and judge theappropriateness of the use of biostatisticalconcepts and tools in the basic public health

    literature.

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    Course Topics

    Types of data, tables and graphs, frequencydistribution

    Measures of central tendency and dispersion

    Population versus sample, sampling distributions,

    normal distribution Point estimates, confidence intervals

    Hypothesis testing concepts

    z-tests, t-tests Sample size determination

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    Course Topics (Contd.)

    Tests for proportions and variances

    Analysis of variance--one-way, randomized

    blocks, factorial designs

    Regression and correlation

    Contingency tables, chi-square tests

    Multiple linear regression

    Relative risk, odds ratios, logistic regression

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    In order to provide a more concrete picture of what

    the course will cover, we will take a brief look at a

    relatively recent article in theAmerican Journal of

    Public Health. To understand this article, you will

    need to understand the basic concepts and many of

    the basic tools of biostatistics. We will review this

    article now and then come back and review it again

    at the end of the course.

    What We Will Cover

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    Article for Review

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    The game plan is for you to be able to understand,interpret and utilize appropriately the information

    in articles such as this. Further, you should be able

    to question whether something was properly done.

    The Game Plan

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    The basic strategy we will follow is to first focus on

    the types of data, then examine tables and graphs and

    frequency distributions. This is critical background

    for understanding samples and populations, estimates

    of population parameters and the fundamental

    elements of hypothesis testing. We will then address

    z-tests, t-tests and many of the other biostatistical

    tools routinely appearing inAJPH. In fact, much of

    the material will be presented in the context of

    relatively recentAJPHarticles.

    The Strategy