ATRAS Work Package 2 Published Evidence. AT Definition An AT is a mechanical or electrical device...
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Transcript of ATRAS Work Package 2 Published Evidence. AT Definition An AT is a mechanical or electrical device...
ATRAS
Work Package 2
Published Evidence
AT Definition
An AT is a mechanical or electrical
device used in a functional task
orientated training process which will
have a systemic or rehabilitative
effect on the person.
WP Progress
• Searched databases• Initial Screening Audited• Developed Website Forms• Allocated Papers• Inter-Library Loans• Share point import data
Access Excel• Spreadsheets for ‘Agreeing Score’
Databases searched
AMED,CINAHL, Cochrane Library
including DARECSA Illumina, EMBASE,MEDLINEPsycInfo,Web of Science,
PeDRo COMPENDEXINSPEC
RECAL Legacy
CIRRIE, REHABDATA
National Research Register (clinical trials),
Reports from professional bodies (RCP Guidelines, CSP),
Papers for scoring
763Screening checked by
2nd reviewer
2424Titles found
464Accepted
95 Review papers
299Rejected
1361Failed
selection criteria
369 Research papers
Initial Screening
Study DesignsLevel Type of Study Number of
Studies
1Case studies or single system study design 95
2
Quasi-controlled studies (same sample repeated measure design) 112
3Quasi-controlled studies (independent sample design)
33
4
Randomised controlled study design (not powered or powered below 80% and 0.05 significance level)
78
RCTs & Quasi-Controlled studies
Technology Level 4 Level 3
BF 3 5CIT 23 3ES 25 9R 11 5
TMS 5 0Trig EMG 6 5
VR 1 1
CPM 1 0CS 2 3
Splint+Btx 1 1
ATs, Joints & Design
BF CIT CS ES ES tr R TMS VR Splint& Btx
0
5
10
15
20
25
UL-4UL-3Sh-4Sh-3E-4E-3W/H-4W/H-3
Review Paper Assessment
Review Paper Assessment
• CRD Guidance
• PeDRo
• DARE
• PRISMA
Review Paper
Assessment
1. Is the purpose of the review clearly defined? 2. Type of review paper 3. Peer reviewed 4. Were search terms reported? 5. Were search terms comprehensive? 6. Was the search strategy reported? 7. Was the search strategy satisfactory? 8 . Were relevant databases searched? 9. No papers excluded on basis of language? 10. Unlimited search timeframe? 11. How many reviewers independently reviewed each paper? 12. How was the validity of studies assessed? 13. Name lowest quality of studies retained for data extraction? 14. Was raw data extracted from papers and/or the research team?15. Was a meta-analysis carried out?16. Were study details synthesised and summarised?
RPA Results
95 Review papers
1 Duplicate
2 Non-English
15 Experimemtal not Review papers
77 Review papersScored
Scored with Van tulder24 Metanalysis
Meta-analysisWoodford HJ; Price CIM
EMG biofeedback for the recovery of motor function after stroke Nov2005
Pomeroy VM; King LM; Baily-Hallam A; Langhorne P
Electrostimulation for promoting recovery of movement or functional ability after stroke (Review) Jan 2004
Mehrholz J; PlatzT; Kugler J; Pohl M
Electromechanical and robot-assisted arm training forimproving arm function and activities of daily living afterstroke (Review) Oct 2007
Price, CIMElectrical stimulation for preventing and treating post-stroke shoulder pain: a systematic Cochrane review Dec1999
Brosseau, L - The Ottawa Panel
Ottawa Panel evidence-based clinical practice guidelines for post-stroke rehabilitation Dec2004
Ada, LStrengthening interventions increase strength and improve activity after stroke: a systematic review Jan 2005
77 Review papersScored
Score Number
12 6
11 5
10 3
9 4
8 3
7 5
≤6 51
van Tulder Scoring
van Tulder Scoring
• Reviewer Name *• Reviewer Order *• Author Name *• Title of article *• Year *• Ref Works ID *
1. Were the eligibility criteria specified?
2. Was a method of randomization performed?
3. Was treatment allocation concealed?
4. Were prognostic indicators similar for groups at baseline?
5.Were the index & control interventions explicitly described?
6. Was the care provider blinded to the intervention?
7.Were co-interventions avoided or comparable?
8. Was the compliance reported in all groups?
9. Was the patient blinded to the intervention?
10.Was the outcome assessor blinded to the intervention?
11.Were the outcome measures relevant?
12.Were adverse effects described?
13.Was the withdrawal/drop-out rate described?
14.Was a short-term follow-up measurement performed?
15.Was a long-term follow-up measurement performed?
16.Was timing comparable for outcome assessment in both groups?
17.Was the sample size for each group described?
18.Did the analysis include an intention-to-treat analysis?
19.Was the variability given for primary outcome measures?
Reviewer's Remarks *
Van Tulder Update
369 +15 papers require 384 agreed scores
41 + 33 = 74 Agreed Scores
542 completed forms
45 same score with out discussion
154 single reviews
Tasks
• Complete van Tulder Screening
• Screen and review updates
• Prepare data extraction form
• WP2 –Data extraction familiarization meeting (wb May 17th at Keele)
Data Extraction
Treatment related• Impairment or Activity
– Odds Ratio (OR)– Effect Size
• Adverse events (OR)• Complexity
– Duration (set up / treatment)
– Frequency– Expertise
Stroke related• Time• Severity• L:R
Tasks 2
• Audit van Tulder Process
• Check Cochrane database and clinical trials register
• Complete data extraction –July/August
• Prepare Report / Matrix for Sept meeting
Join us in May
Thanks For Reviewing