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Organized by

Malaysian Society of Infectious Diseases & Chemotherapy (MSIDC)

Tropical Infectious Diseases Research & Education Centre (TIDREC) WHO Collaborating Centre (WHOCC) for Arbovirus Reference & Research

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Aesculap Academy

Supported by

Ministry of Health Malaysia (MOH)

ASIA DENGUE CONFERENCE Dengue : New Challenges, New Strategies

23 - 24 April 2016 I JW Marriot Kuala Lumpur, Malaysia

Dr Ashok Zachariah Philip President Malaysian Medical Association 4th Floor, Bangunan MMA 124 Jalan Pahang, 53000 Kuala Lumpur Wilayah Persekutuan

Dear Dr Ashok

ASIA DENGUE CONFERENCE

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23- 24 April 2016, JW Marriot Kuala Lumpur. Malaysia

4 February 2016

On behalf of the Organizing Committee, we would like to seek the support of the Malaysian Medical Association (MMA) for the Asia Dengue Conference, which is co-organised by the

• Malaysian Society of Infectious Diseases & Chemotherapy (MSIDC)• Tropical Infectious Diseases Research & Education Centre (TIDREC)• Aesculap Academy, and• WHO Collaborating Centre (WHOCC) for Arbovirus Reference & Research

This conference is also supported by the Ministry of Health Malaysia and is targeted to all medical doctors, other medical professionals, researchers and academics involved in the management and research of dengue.

Drawing expertise from more than twenty international and local speakers, the scientific committee has put together a comprehensive programme which features seven (7) plenary sessions and eleven (11) concurrent symposia.

We would be grateful if the MMA could support this conference by allowing us to publish this event in the MMA's website, as well as to forward the announcement to all members of the association.

We enclose a copy of the first announcement for your reference and consideration.

Thank you for your support and we look forward to a favourable reply from you.

Yours sincerely

Om� £1hira, """"' Head of Department & Senior Consultant Physician for Infectious Diseases Hospital Raja Perempuan Zainab II, MOH Organizing Chairperson, Asia Dengue Conference

""""2:.,, "'" , .... Head of Tropical Infectious Diseases Research and Education Centre & WHO Collaborating Centre for Arbovirus Reference & Research (Dengue/ Severe Dengue), University Malaya Organizing Co-Chairperson, Asia Dengue Conference

Secretariat Aesculap Academy Malaysia

Crown Penthouse, Plaza IBM, 8 First Avenue, Persiaran Bandar Utama, 47800 Petaling Jaya, Selangor, Malaysia Tel: ++603-78414200 I Fax: ++603-7729 6715 I Email: aes_academy@bbraun.com

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DENGUE CONFERENCE

Dengue : New Challenges, New Strategies

23 - 24 April 2016 I JW Marriot Kuala Lumpur, Malaysia

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WliO ColtaboraUng Centre (WHOCC) for Arbovlrus Rafer1mce & Research

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ACADEMY

Introduction Dengue has emerged as a worldwide problem since the 1950s. About half of the world's population is at risk of this mosquito-borne disease. Dengue is found in tropical and sub-tropical climates areas, with cases reported in more than 150 countries. Dengue patients show non-specific febrile syndrome in

early stage which may delay early diagnosis. Although not all dengue Infections result in illness, some dengue patients may progress to life-threatening haemorrhagic fever and dengue shock syndrome. Today, we are facing huge challenges in managing dengue associated complications which can lead to hospitalizations· and/or deaths.

In view of these challenges and with the support from the Ministry of Health Malaysia, the Malaysian Society of Infectious Diseases & Chemotherapy (MSIDC), Tropical Infectious Diseases Research &

Education Centre (TIDREC), Aesculap Academy and WHO Collaborating Centre (WHDCC) for Arbovirus Reference & Research have taken the initiative to provide a platform to address various pertinent issues on the challenges, diagnosis, treatment and best practices in managing this growing menace in the region.

Drawing expertise from more than twenty international, ASEAN and local speakers, the scientific committee has put together a comprehensive programme which features seven (7) plenary sessions and eleven (11) concurrent symposia, covering topics such as:

Clinical Predictors of Severe Dengue Dengue Vaccination : Current landscape in Asia Innovative strategies & tools for dengue surveillance & control Dengue detection tools Viral Tropism and pathogenesis Updates on Pathophysiology of Dengue Infection Challenges and Strategies to Decrease Dengue Morbidity & Mortality Sharing of Experience from various countries in ASEAN on Monitoring In Severe Dengue, Advances in Lab Diagnosis for Dengue, Fluid Management in Dengue, Best Practices in Vector Control, Dengue in Special Groups, and many more.

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About the Conference

Date 23 - 24 April 2016 Venue : JW Marriot Kuala Lumpur, Malaysia

Organizing Committee Patron Advisor Chairperson Co-Chairperson Scientific Committee Members

Secretariat Aesculap Academy Malaysia

YBhg Datuk Dr Noor Hisham Abdullah YBhg Datuk Dr Jeyaindran Tan Sri Sinnadurai YBhg Dato' Dr Mahiran Mustafa Professor Dr Sazaly Abu Bakar YBhg Datuk Dr Christopher Lee Professor Dr Zamberi Sekawi Dr Rose Nani Mudin Dr Suresh Kumar Chidambaram Dr Sharifah Faridah Syed Omar Dr Anilawati Mat Jelani Dr Zainanda Zainal Dr Tahir bin Aris Dr Teoh Boon Teong Dr Ravindran Thayan Associate Professor Datin Dr Noor Zetti Zainol Rashid Dr Nor Azilah bt Abu Bakar@ Mansor Dr Siti Zubaidah binti Ahmad Subki Dr Khoo Jing Jing Pn Juraina Abd Jamil

Crown Penthouse, Plaza IBM, 8 First Avenue, Persiaran Bandar Utama 47800 Petaling Jaya, Selangor, Malaysia Tel: +603-7841 4200 Fax: +603-77296715 Email: aes_academy@bbraun.com Website: www.tidrec.com

Target Audience

All medical doctors, other healthcare professionals and researchers involved in the management and research of dengue.

Continuous Professional Development (CPD) Accreditation Continuous Professional Development (CPD) points will be awarded by the Ministry of Health Malaysia and the Malaysian Medical Association to all participants who have attended the full duration of the programme.

Pre-Conference Workshop on Dengue Molecular Detection

Date Venue

21 - 22 April 2016 Surveillance Laboratory, TIDREC Department of Medical Microbiology, University Malaya

In this two-day pre-conference workshop, participants will be exposed to the molecular techniques employed for the detection of dengue viruses from clinical or research materials. This workshop is targeted to academics, researchers, laboratory personnel and students interested in the laboratory detection, diagnosis and surveillance of dengue.

The workshop incorp.orates lectures, hands-on practical sessions and discussions on up-to-date techniques of the conventional and most recently developed technologies for detecting and serotyping of dengue viruses, including quantitative RT-PCR and the Recombinant Polymerase Amplification (RPA).

This workshop is limited to 20 places only. Due to limited places, registration is on a first-come-first-served basis. Confirmation of registration is upon receipt of the registration form (Attachment 1) and proof of payment. Early registration is highly recommended in order to avoid disappointment.

For more information and details on the tentative program, please visit www.tidrec.com.

'!\ Confirmed Overseas Faculty

Singapore Professor Dr Leo Yee Sin Dr Ng Lee Ching Professor Annelies Wilder- Smith

Thailand Associate Professor Pattamaporn Kittayapong Professor Dr Kovit Pattanapanyasat Professor Dr Usa Thisyakorn Associate Professor Dr Nattachai Srisawat

Taiwan Professor Yee-Shin Lin Associate Professor Guey-Chuen Perng Dr Ruby Tsai Jih-Jin

Indonesia

Vietnam

Philippines

Dr Herman Kosasih

Dr Nguyen Minh Tuan Dr Sophie Yacoub

Dr Rabindra Abeyasinghe

Confirmed Local Faculty

Datuk Dr Lokman Hakim Sulaiman

Dr Faridah Amin

Dato' Dr Mahiran Mustafa

Dr Chow Ting Soo

Dr Kan Foong Kee

Dr Ravindran Thayan

Dr Nazni Wasi Ahmad

Professor Dr Lucy Lum Chai See

Professor Dr Sazaly Abu Bakar

Dr Rose Nani Mudin

Dr Shanti Ratnam

Dr Faisal Salikin

DrTeoh Boon Teong

Dr Sharifah Faridah Syed Omar

Associate Professor Dr Wong Li Ping

Associate Professor Hoh Boon-Peng

Registration

For registration, please submit completed Registration Form (Attachment 1) to the Secretariat at aes_academy@bbraun.com

Registration Fees

Local I Malaysian Delegate

Pre�Conference Workshop (only) 21-22April 2016

Workshop on Dengue RM954 Molecular Detection (without accommodation)

Conference (only) 23 - 24 Aprll 2016

Before 11 March 2016 RMS SO

(without accommodation)

After 11 March 2016/Walk-in RM650

(without accommodation)

Method of Payment Payment of registration fees can be made via:

Telegraphic Transfer Online IE-Payment (kindly contact the Secretariat for details) Cheque I Money Order I Bank Draft (drawn from a Malaysian bank)

All payments are to be made payable to: Account Name B. Braun Medical Supplies Sdn BhdAccount No 0004333000

Sank Deutsche Bank (M) Shd

Overseas Delegate

USD400 (without accommodation)

USDSOO (with 3 nights accommodation)

USD850 (with 3 nights accommodation)

Swift Code

8, Jalan Sultan Ismail, 50250 Kuala Lumpur, Wilayah Persekutuan

DEUTMYKL

Registration Fees Entitlements

Admission to scientific programme (accordingly)

Meals as stated in programme Certificate of Attendance 3 nights accommodation (for Overseas delegate registered for the Conference only)

Hotel Accommodation Where registration fees do not cover accommodation, delegates are advised to make their own accommodation arrangements at their preferred hotel suggested below:

The Westin Kuala Lumpur 199, Jalan Bu kit Bintang, 55100 Kuala Lumpur Contact No: ++603 2731 8333 Distance from JW Marriott KL: 1 minute

Hotel Pullman Kuala Lumpur City Centre No 4, Jalan Conlay, 50450 Kuala Lumpur Contact No: ++603 2170 8660 Distance from JW Marriot KL: 3 - 4 minutes

Grand Millennium Kuala Lumpur 160, Jalan Bukit Bintang, 55100 Kuala Lumpur Contact No: ++603 2117 4888 Distance from JW Marriott Kl: 4 minutes

Izumi Hotel No 85, Jalan Berangan (Off Jalan Bukit Bintang) 50200 Kuala Lumpur

Contact No:++603 2145 8833 Distance from JW Marriott KL: 7 minutes

Cancellation I Replacement Clause

Dorsett Regency Kuala Lumpur 172, Jalan lmbi, 55100 Kuala Lumpur Contact No: ++603 2716 1000 Distance from JW Marriott KL: 1 minute

Novotel Kuala Lumpur City Centre 2, Jalan Kia Peng, 50450 Kuala Lumpur Contact No: ++603 21470888 Distance from JW Marriott KL: 7 minutes

The Royale Bintang Kuala Lumpur 17-21,Jalan Bukit Bintang, 55100 Kuala LumpurContact No: ++603 2143 9898Distance from JW Marriott KL: 8 - 13 minutes

The Federal Kuala Lumpur Hotel 35, Jalan Bukit Bintang, 55100 Kuala Lumpur Contact No: ++603 2148 9166 Distance from JW Marriott KL: 9 -11 minutes

Any cancellation or replacement must be conveyed to the Secretariat in writing ten (1 O) days prior to the Conference. Otherwise, an administrative fee of 20% of the registration fee will be charged for

cancellation and any replacement will be processed as a new chargeable registration.

Liability The Organizers shall not be held liable for personal accidents or losses or damage to private property of registered participants of the Conference.

Disclaimer

Whilst every attempt will be made to ensure all features of the programme mentioned in this announcement will take place as scheduled, the Organizing Committee reserves the right to make

last minute changes should the need arise.

Call for Abstract

The Scientific Committee welcomes the submission of abstracts for poster presentations in the Clinical, Public Health and Diagnostics categories.

Deadline for Submission 3 March 2016

Notice of abstract acceptance will be sent to all short listed authors by 11 March 2016.

Abstract format

Abstract should be submitted in Microsoft word format

Can be written in either British English or American English, but the language usage must be consistent throughout the abstract

Must not exceed 250 words

Font: Times New Roman, size 12, line spacing 1.5

Must fit in one page (in case of exceeding one page, smaller font size is acceptable)

The title should be bold

Author's name should be written as Last Name, First Name Initials (e.g. Smith, J)

Underline the presenting author's name

Use superscripted numbers (Smith, Jl) to distinguish authors with different affiliations

No references should be cited

No keywords

Abstract submission

Abstracts can be submitted on line to aes_academy@bbraun.com together with a completed Abstract Submission Form (Attachment 2).

Each registered participant is allowed to submit one or more abstracts

Program at a glance

Day 1 · 23 April 2016 (Saturday)

8.00am Plenary 1 : Dengue as a global health threat in Western Pacific Region

8.4Sam Plenary 2 :Two decades of dengue in Malaysia

9.30am Welcome Message & Opening Ceremony

10.30am Tea/ Coffee Break & Poster Viewing

11.30am Symposium 1 : Severe Symposium 2 : Symposium 3: Innovations in Dengue Management Dengue Prevention Dengue Diagncisis & SurveillancE

1.00pm Lunch Symposium

1.4Spm Plenary 3: Clinical predictors of severe dengue

2.30pm Plenary 4: Dengue vaccination: Current landscape in Asia

3.1Spm Tea/ Coffee Break & Poster Viewing

4.1Spm Symposium 4 : Fluid Symposium 5: Best Symposium 6: Dengue Management in Dengue Practices in Vector Control Epidemiology & Diagnosis

S.4Spm End ofDay 1

Day 2 • 24 April 2016 (Sunday)

8.00am Plenary 5: Innovative strategies & tools for dengue surveillance & control

8.4Sam Plenary 6: Early megakaryocytic lineage cells are essential in dengue viral tropism and pathogenesis

9.30am Plenary 7: Microvascular function in dengue

10.lSam Tea/ Coffee Break & Poster Viewing

11.lSam Symposium 7: Symposium 8: Primary Care Symposium 9 : Dengue Dengue in Special Groups Providers As Gate Keepers Pathogenesis

12.4Spm Lunch

2.30pm Symposium 10: Symposium 11 : Strategies to Dengue Complications Decrease Dengue Morbidity

&Mortality

4.00pm Tea I Coffee & End of Conference

Asia Dengue Conference (Tentative Program)

Day 1 : 23 April 2016 (Saturday)

8.00am

8.4Sam

9.30am

Chairperson : Datuk Dr Christopher lee

Plenary 1: Dengue as a global health threat in Western Pacific Region

Dr Rabindra Abeysinghe (WHO Regional Office for the Western Pacific)

Plenary 2: Two decades of dengue in Malaysfa

Oatuk Dr Lokman Hakim Sulaiman (Ministry of Health, Malaysia)

Welcome Message from Organising Chairperson (10mins)

Opening Ceremony by VIP {20mlns)

Bleeding and dengue

11.30am Dr Sharlfah Farldah Syed Omar (University Malaya Medlcal Centre,

Malaysia)

12.00pm

12.30pm

The role of non invasive equipments in monitoring & management

Dr Shanti Ratnam (Hospital Sungai Bulah, Malaysia)

Acidosis & hyperlactatemla in severe dengue

Dr Nattachal Srisawat {Chulalongkorn University, Thailand)

1.00pm Lunch Symposium

1.45pm

2.30pm

4.15pm

4.45pm

S.15pm

Chairperson : Dato' Dr Hussain Imam bin HJ Mohammad Ismail

Plenary 3: Clinical predictors of severe dengue

Prof Dr Leo Yee Sin (Tan Tock Seng Hospital, Singapore)

Plenary 4: Dengue vaccination: Current landscape In Asia

Prof Usa Thlsyakorn (Asean Dengue Vaccination Advocacy, Thailand)

Who needs only oral fluid?

Dr Chow Ting Soo (Hospital Pulau Pinang, Malaysia)

Fluid management In severe dengue

Dr Nattachai Srisawat (Chulalongkorn University, Thailand)

Controversies in Collo!d vs Crystalloid use for resuscitation in DSS

To be confirmed

S 45pm End of Day 1

Symposium 2 : Dengue Prevention

Chairperson: Dato' Dr HJ Ahmad Razin bin Dato HJ Ahmad Mahlr

Dengue prevention in school chlldren

A/Prof Pattamaporn Klttayapong (Mah idol University, Thailand)

Strategies for sensitive & early diagnosis of dengue

Prof Sazaly Abu Bakar (TIDREC, Malaysia)

Factors influencing dengue prevention practices Dengue RPA: A rapid dengue virus detection method

A/Prof Dr Wong LI-Ping (University Malaya Medical Centre, Malaysia, Malaysia) Dr Teoh Boon Teong {TIDREC, Malaysia)

Integrated management in dengue

Dr Rose Nani binti Mudln (Ministry of Health, Malaysia)

Chairperson : Dr Chong Chee Kheong

Overcoming the challenges- Best practices from Malaysia

Dr Nazni Wasi Ahmad {Institute for Medical Research, Malaysia)

Dengue outbreak during 2014-2015 In Taiwan

Dr Ruby Tsai Jlh-Jin (Kaohsiung Medical University Hospital, Taiwan)

Overcoming the challenges- Best practices from Singapore

Dr Ng Lee Ching (National Environment Agency, Singapore)

Advances In molecular detection of dengue

Dr Ravindran Thayan (Institute for Medical Research, Malaysia)

Evolution of dengue viruses in recurring dengue outbreaks

Prof Sazaly Abu Bakar (TIDREC, Malaysia)

Molecular insights Into dengue epidemics

Dr Ool Eng Eong (Duke-NUS Medical School, Singapore)

Genotype and serotype dengue surveillance

Dr Faridah binti Amin (National Public Health Laboratory, Malaysia)

8.00am

8.4Sam

9.30am

11.lSam

11.45am

12.lSpm

2.30pm

3.00pm

3.30pm

Plenary 5 : Innovative strategies & tools for dengue surveillance & control Prof Annelles Wilder-Smith (Nanyang Technology University, Singapore}

Plenary 6: Early megakaryocytic lineage cells are essential in dengue viral tropism and pathogenesis A/Prof Guey-Chuen Perng (National Cheng Kung University, Taiwan)

Plenary 7 : Microvascular function in dengue

Or Sophie Yacoub (Oxford University Clinical Research Unit, Vietnam)

Dengue in pregnancy

To be confirmed

Severe dengue in paediatric

Prof Or Lucy Lum Chai See (University Malaya Medical Centre,

Malaysia)

Dengue in elderly Dr Monica Chang (Singapore)

Haemophagocytic syndrome In severe dengue

Dr Kan Foong Kee (Hospital Sultanah Amlnah, Malaysia)

Dengue myocarditis

Or Sophie Yacoub (Oxford University Clinical Research Unit,

Vietnam)

Dengue Hepatitis/Encephalitis

To be confirmed

To be confirmed

Or Herman Kokaslh (Indonesia Research Partnership on Infectious Diseases,

Indonesia)

Point of care testings for dengue at primary health centre - ABC guide in clinical interpretation

Dato' Dr Mahlran Mustafa (Hospital Raja Perempuan Zalnab II, Malaysia)

Triaging in dengue Or Faisal Sallkln (Hospital Kuala Lumpur, Malaysia)

Dr Mario Baquilod (National Center For Disease Prevention and Control, \

Developing admission criteria for dengue Prof Leo Yee Sin (Co'!lmunicable Disease Centre, Singapore)

Decreasing case fatality rate - Vietnam experience Or Nguyen Minh Juan (Children's Hospital 1, Vl�tnam)

Host predictors in dengue infection

A/Prof Boon-Peng Hoh (UCSI UnlVersity, Malaysia)

Innate immune mechanisms in dengue virus infection

Prof Dr Kovit Pattanapanyasat (Mahldol University, Thailand)

Dengue virus NSl antigen: A vaccine candidate?

Prof Yee-Shin Lin (National Cheng Kung University, Taiwan)