Artificial Intelligence As A Service

Detecting good and bad bacteria in

skincare, healthcare and water

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Former Operations Director

at Campbell Bewley Group

before becoming Chief of

Operations at Alltracel

Pharmaceuticals Member of

the Institute of Chartered

Accountants

Camillus GloverChief Finance Officer

Appointed Aug 2018

CEO of Cellulac.

Founder and CEO of

Alltracel Pharmaceuticals

and Managing Partner at

Farmabrand PE, Fellow of

the Ryan Academy of

Entrepreneurs

Gerard BrandonChief Executive Officer

Appointed Aug 2018

Extensive experience as

advisor to AIM Companies.

Former director Zeus Capital

and a Non-Executive Director

of a number of Listed

Companies across a Range of

Sectors

Ross AndrewsNon-Executive Chairman

Appointed Mar 2017

Experienced operational management team increasing

sales, margins and corporate initiatives

Founder of Rinocloud. 30-

year Senior Executive in high

growth enterprise software

(SaaS) systems for Financial

and Government Services,

Global Biotech and Domestic

Energy & Water Utilities

Fionan MurrayChief Operations Officer

Appointed May 2019

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Corporate Profile

Market AIM

Ticker SKIN

Share Price (Avg 3mth) 1.66p

Market Cap (Avg 3mth) £17.8m

NOMAD SPARK Advisory Partners

Broker Turner Pope Investments

Director Shareholding

Fionan Murray 8.19%

Gerard Brandon 4.68%

Camillus Glover 3.96%

Ross Andrews 0.21%

Disclosable Shareholders

Helium Rising Stars Fund 7.37%

Cellulac plc 3.56%

Integumen is a vertically integrated physical and cloud-based

company focused on commercialising AI test services for good

and bad bacteria in skincare, healthcare and water.

Labskin is a test platform that scientifically proves the impact of

skincare product claims for healthcare, life sciences, clinical

research, pharmaceutical and cosmetics industries.

Rinodrive is a data aggregation, refining and AI analysis open-

source eco-system designed to provide third-party service

providers the ability to offer clients valuable insights to support

clinical, operational and financial decisions in healthcare services,

third-level education, government departments and the financial

sector.

ecowaterOS, or, Ecological Water Operating System, is a

Greentech data management eco-system that monitors and

analyses water for contamination using artificial intelligence,

providing stakeholders, from water utilities to consumers, alerts to

contamination of water supplies in real-time.

Overview

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• 2019 revenue increases 366% to £1m (unaudited)

• 2020 guidance - organic growth - of 300% to £4m

• Gross Margins 78%

• Dec 2019: £1.38m Placing at 1.5p

• May 2019: Acquisition of Rinocloud for £3m with

£2.5m placing, subscription and elimination of £2.2m

debt to leave a stronger balance sheet.

• Oct 2019: Multi-year service agreements Top 10

global cosmetic and skin care client base

• Feb 2020: Partnership with Acumen Software for

cross selling wastewater utility clients on 4

continents and launch of EcoWaterOS

Highlights

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1,045

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1000

1500

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2500

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3500

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Year End 2018 October End 2019 Year End 2019 Year End 2020

Sales To Dec 2020

Business Model Transformation & Results

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Trend from start of 2018 to present

Moved from selling kits to services

Current Average Service Order Values

Top 20 Global Skincare companies

A* £87,000

B* £99,000

C* £42,500

D* £45,000

L’Occitane £33,000

F* £27,000

* Subject to NDA

Artificial Intelligence As A Service

AI - INTERNET OF THINGS (WATER MONITORING)

AI DATA ANALYTICS (PUBLIC & PRIVATE SECTOR)

SKINCARE, HEALTHCARE, PERSONAL CARE PRODUCT TESTS

AI DISEASED HUMAN LABORATORY SKIN MODEL SERVICES

R&D CONSORTIUM PROJECTS (SOCIETAL SKIN DISEASES)

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➢ Labskin + AI - ethical-animal-free 3D skin that

mimics human skin

➢ Disruptive - reduce the cost and time of

skincare tests & product development

➢ Cloning healthy and diseased human skin -

creates lab-grown eczema and psoriasis using

AI data analytics to support new product

development

➢ Virtual microbiology AI laboratory - test

services for skincare, healthcare, personal

care, wound care manufacturing companies

➢ 12 years development - designed to host

microbiota (bacteria, fungi and viruses) creates

living diseased skin models that mimic real

human skin

Labskin

o Controlled, more ethical testing

o Faster testing than on human subject

o Labskin tests cannot be done on humans

o Less trials need to be done on humans

o Generates more accurate data

o Treatment can be monitored by

• Swabbing the surface of patients skin

• Evaluate the effect on skin microbiome

• Adjust remedies accordingly

How does AI save substantial time and costs?

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1 Human

Volunteer

2 Cloned

Volunteers

Microbiome Psoriasis Model

• Dataset initial formatting as required

• Dataset shuffled

• Data split of 80% for training – 20% validation

• Full feature set identified (217 features)

• Hyperparameter tuning using GridSearchCV

• Best parameter analysis:

{'criterion': 'entropy', 'max_depth': 28, 'max_features': 'log2'}

Opportunity Improvement Opportunity Switch Opportunity Stack

Better than current petri dish

protocols. A lot of effort. Learning to

use Labskin by themselves. A tough

sale

Converting clients from Animal

testing to Labskin Quality

Standards using

“Done For You” services

Running parallel testing programs

with Labskin Training. Combined

with their own testing kits and

consumables

e.g. 33 x £1,500 = £49,500 e.g. 10 x £25,000 = £250,000 e.g. 10 x £46,000 = £460,000

Moved from £1,500 test-kit sales to c£46,000 AI data analytic services

H1 2018 H2 2018 2019

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Clinical ResearchEnhance Margins

Double the Test Results

Half the Test Volunteers

Half the CRO Project Managers

Faster Reliable Consistent Results

e.g. 20 x £200,000 = £4,000,000

Disruptive Business Model in 2019 - 2020

EU Regulation 2017/745 – Medical Device Directive - Rule 21

2020Current Rolling Out

50 Human Volunteers = 100 Cloned Test Subjects

AI Transforms Clinical Research OpEx

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Labskin Physical Operations –

Scaling to meet demand

New Laboratory Space gives us twice the service delivery capacity.

Further intended expansion into the available lab space in the same

corridor:

● Additional Tissue Culture Labs for Labskin production

● Additional Microbiology Labs for Microbiome testing

● Dedicated Analytical Service Laboratory, including next generation

sequencing equipment.

● Dedicated immunohistochemistry and Media preparation Labs to

support production and services.

● Additional office space available for Shared Services Centre

To meet the rapid demand from clients we can provide an estimated

10+ times 2019 turnover capacity in 6-12 months

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More diseased skin models

Young skin models

3 Cell model for South East Asia skin type

UV damaged skin models

Generate more data with Gene Sequencing

Continue training AI models – more skin diseases

Global Water Crisis sector use – e.Coli bacteria in water, mastitis in milk, malaria in blood

Product/Solution – Roadmap

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RAWTest Monitoring

Classification of E.coli in our rivers and lakes using Artificial Intelligence

10,000+ water samples taken and used as training data.

Suite of AI Models

Logistic Regression, Random Forest, Extra Trees Alg., Artificial Neural

Networks (Multi Layer Perceptron) , Support Vector Machines (SVM)

Data visualisation in real time

Complex to understand datasets for science translated in real time to an easy

to understand format for science teams

Scalable web applications & web services

Custom web applications built to handle data pipelines and data interaction through

dashboards

Latest Machine Learning Technology

Scikit-Learn, Amazon Sagemaker, Python, Flask, Numpy, Scibio Library

(Remote Autonomous Water Test)

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Data Visualisation in Real-Time3.37 seconds – 99.3% Accurate

Normally takes from 24-72 hours

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How clean is your drinking water?

How clean is your

drinking water?

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Investment Case For Any Business Case - Integumen

o How big and what is the market being addressed?

o Skincare market $183 billion expanding at 4.5% CAGR to 2025

o Global water treatment market $23.8 billion in 2016 and CAGR 7.1% by 2025

o How unique and how big is the moat around the technology?

o Skincare Labskin + Microbiome + AI unique combination ring-fenced by 12 years of data collection

o Water contamination detected in 3.37 seconds, 99% accuracy – Normally takes 24 to 72 hours

o Is the timing right?

o This is the Selfie Society and how your skin looks is more important to some people than life itself

o Population explosion, climate change, carbon footprint reduction, water crisis is the new normal

o Is it the right execution team?

o Management team has created, built and exited multiple, multi-national businesses across 6 continents