Arbovirus Flash Cards

8/10/2019 Arbovirus Flash Cards

1/11

Term 1

Encephalitis

Symptoms and signs indicating

involvement of brain parenchyma

Definition 1

Seizures, alteration of consciousness,

visual disturbances, paralysis of

extremities

Term 2

For aseptic meningitis the mild disease

is the norm.

If someone does have issue who will it

be and why?

Definition 2

Children - deafness, psychomotor

difficulties, learning disabilities

Because brain not fully myelinated

Term 3

arboviruses productively infect an

unusually

Definition 3

wide range of animal reservoirs


2/11

Term 4

what is the role played by human with

arboviruses

Definition 4

dead end host ( NOT always... mostly

though)

Viremia is weak or not sustained in

humans and does not allow for

efficient infection of new vectors

(amplification)

Term 5

What are big tests for arbovirus

detection?

Definition 5

IgM antibody capture ELISA (MAC-

ELISA) CAREFUL: crossreact ( he said

to KNOW limitations of the test) can

also

test for virus specific antibody using

CSF or serum to make test more

accurate. ( look for 4x increase)

Monitoring arboviruses in area (Vector

control districts, public health office)

Term 6

is culture of arbovirus typical?

Definition 6

NOOO


3/11

Term 7

The arboviral encephalitides are

_________ with reservoirs and means

of dispersal in animals other thanhumans

Definition 7

zoonoses

Term 8

In arboviruses the arthropod is a true

______ vector.

The infected vector often shows no

obvious signs of disease

Definition 8

biological

Term 9

Arbovirus transmission to humans

requires____________that will feed

avidly on both animal reservoir hosts

and humans.

Definition 9

bridge vectors


4/11

Term 10

what is the Sylvatic cycle?

what is the Urban cylce?

Definition 10

sylvatic cycle-humans are tangential

hosts accidentally entering a natural

zoonotic transmission cycle

Urban cycle -- Situation of large human

population coexisting with large vector

populations such as mosquitoes. ( in

this cycle the virus DOES replicate in

us!!! )

Term 11

Humans do exhibit sufficient viremia to

sustain true urban cycles for what

three arboviruses?

Definition 11

St. Louis encephalitis, Yellow Fever

and Dengue

Term 12

Is complete eradication plausible for

arbovirus? what is the best

prevention? ( 3 ways)

Definition 12

Because arboviruses have hosts and

cycles that do not normally involve

humans, complete eradication is

simply not feasible.

The best means of control is to

interrupt the fundamental chain of

transmission:

1. Eradication/control of arthropod

vectors2. Avoidance of exposure

3. Immunization of nonhuman

amplifying hosts (Horses/pigs)


5/11

Term 13

Double stranded RNA genome of 12

segments

Definition 13

Coltivirus structure

Term 14

Single stranded (+) RNA

Enveloped

Hemagglutinin is present in envelope

Cytoplasmic replication

Definition 14

Togaviruses structure ( includes

Genus Alphavirus and Genus

Flavivirus )

Term 15

Genome is 3 circular segments of

single stranded (-) sense RNA

Enveloped

Spherical shape

Definition 15

Bunyaviruses structure


6/11

Term 16

EEE has __________ reservoirs with

mosquito vectors

Definition 16

bird and horse

Term 17

Primarily virus transmission will be

concentrated in permanent swamps

and at the edges of such swamps

Definition 17

EEE

Term 18

Most ______ cases are in infants and

children under 10 years age

Definition 18

WEE


7/11

Term 19

To carry infection to humans,

other mosquito vectors must

act as bridge vectors

Definition 19

EEE

Term 20

Clinically overt encephalitis in children

under 15 and adults over 55 mostly

Definition 20

EEE

Term 21

Most years WEE is a sporadic endemic

infection, but disease outbreaks do

occur in which cases will

Definition 21

number in the hundreds


8/11

Term 22

This usual mosquito vector is adapted

to flooded grounds and irrigated

pastures

Definition 22

WEE

Term 23

Bird reservoir with mosquito vector

Sparrows are a principal amplifying

host, but vectors will vary with

geographic location

Definition 23

St louis

Term 24

Infants and adults over age 40 at

highest risk

Attack rates and severity of illness

increase with age

Definition 24

st. louis


9/11

Term 25

_________is unusual in that about

20% of total infections result in

clinically apparent illness.

Febrile illness of sudden onset lasting

3-6 days

Definition 25

WNV

Term 26

This one hits School-aged children

6 months-16 years, boys especially

Definition 26

California encephalitis virus

Term 27

Small mammal reservoir (chipmunks

and squirrels) with mosquito vector

Definition 27

California encephalitis virus


10/11

Term 28

California encephalitis virus is

endemic to

Definition 28

Midwest

Term 29

______ is a Reovirus in the genus

Coltivirus

Definition 29

CTF

Term 30

what is the vector and reservoir for

CTF?

Definition 30

The vector is the wood tick, reservoirs

are ground squirrels and chipmunks

(Said we had to know!! esp: tick)


11/11

Term 31

Patients infected with ______ should

not donate blood for at least 6 months

Definition 31

CTF

Virus nonlethally infects erythroid

precursor cells and can persist for

months in erythrocytes

Term 32

which disease has a Saddle backed

fever pattern:

2-3 days of fever, afebrile interval of

several days, followed by 2-3 days of

fever

Definition 32

CTF

Term 33

Which arbovirus has the greatest risk

of infection in the evening and in areas

of low socioeconomic status

Definition 33

St louis

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