Approche thérapeutique en oncologie: Le point de vue de l ... · Guy Jerusalem CHU Liège / ULg...
Transcript of Approche thérapeutique en oncologie: Le point de vue de l ... · Guy Jerusalem CHU Liège / ULg...
Guy Jerusalem CHU Liège / ULg
Approche thérapeutique en oncologie: Le point de vue de l’oncologue
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Background
Presented By Al-Baimani et al. WCLC 2015 Abstr 1398
Most patients are trial ineligible
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Practice changing trials: Eligibility in organ failure
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
What is a reasonable approach?
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Mortality in advanced non-cancer illnesses
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Non-cancer illnesses with prognosis < 6 months
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Cancer and dialysis
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
So you decide to go ahead with therapy
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Which drug to pick?
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Is there a right to try ?
Presented By Paul Wheatley-Price at 2016 ASCO Annual Meeting
Discussion and conclusions
Presented By William Tse at 2015 ASCO Annual Meeting
Presented By Lindsay Peterson at 2015 ASCO Annual Meeting
Older Adult Population on the Rise
Presented By William Tse at 2015 ASCO Annual Meeting
Renal Function Declines with Age
Presented By Lindsay Peterson at 2015 ASCO Annual Meeting
Renal Function Declines with Age
Slide 3
Presented By Lindsay Peterson at 2015 ASCO Annual Meeting
Presented By Heidi Klepin at 2015 ASCO Annual Meeting
There is little evidence to guide management decisions
Most older adults are taking multiple medications
Presented By Heidi Klepin at 2015 ASCO Annual Meeting
Most older adults are taking multiple medications
Polypharmacy increases the risk of drug interactions
Presented By Heidi Klepin at 2015 ASCO Annual Meeting
Polypharmacy increases the risk of drug interactions
Association between renal function and chemotherapy toxicity in older adults with cancer
Presented By Lindsay Peterson at 2015 ASCO Annual Meeting
Study Design- Outcomes
Presented By Heidi Klepin at 2015 ASCO Annual Meeting
Study Design - Outcomes
Serum Creatinine and Chemotherapy Toxicity
Presented By Lindsay Peterson at 2015 ASCO Annual Meeting
Serum Creatinine and Chemotherapy Toxicity
Renal Function and Chemotherapy Toxicity (Cockcroft-Gault, Actual Body Weight)
Presented By Lindsay Peterson at 2015 ASCO Annual Meeting
Renal Function and Chemotherapy Toxicity (Cockcroft-Gault, Actual Body Weight)
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Merci pour votre attention!