Application of DNA self-assemblyinoue/assets/img/archive-pdf/190707...Application of DNA...
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Application of DNA self-assembly
“from origami to computer”
2019/07/13 Akira Hirose
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Contents
1. Introduction
- What is DNA nanotechnology?
- DNA origami
2. Previous Studies on DNA Computers and
Winfree’s Enzyme-Free Nucleic Acid Logic Circuits
Seelig, G.; Soloveichik, D.; Zhang, D. Y.; Winfree, E. Science
2006, 314, 1585.
3. Diverse and robust molecular algorithms using
reprogrammable DNA self-assembly (main topic)
Woods, D.; Doty, D.; Myhrvold, C.; Hui, J.; Zhou, F.; Yin, P.;
Winfree, E. Nature 2019, 567, 366.
![Page 3: Application of DNA self-assemblyinoue/assets/img/archive-pdf/190707...Application of DNA self-assembly “from origami to computer” 2019/07/13 Akira Hirose Contents 1. Introduction](https://reader034.fdocuments.in/reader034/viewer/2022042220/5ec666ab2a5b1b797e2aa000/html5/thumbnails/3.jpg)
Contents
1. Introduction
- What is DNA nanotechnology?
- DNA origami
2. Previous Studies on DNA Computers and
Winfree’s Enzyme-Free Nucleic Acid Logic Circuits
Seelig, G.; Soloveichik, D.; Zhang, D. Y.; Winfree, E. Science
2006, 314, 1585.
3. Diverse and robust molecular algorithms using
reprogrammable DNA self-assembly (main topic)
Woods, D.; Doty, D.; Myhrvold, C.; Hui, J.; Zhou, F.; Yin, P.;
Winfree, E. Nature 2019, 567, 366.
![Page 4: Application of DNA self-assemblyinoue/assets/img/archive-pdf/190707...Application of DNA self-assembly “from origami to computer” 2019/07/13 Akira Hirose Contents 1. Introduction](https://reader034.fdocuments.in/reader034/viewer/2022042220/5ec666ab2a5b1b797e2aa000/html5/thumbnails/4.jpg)
1-1. What is DNA Nanotechnology? (1)
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1-2. What is DNA Nanotechnology? (2)
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1-3. What is DNA Nanotechnology? (3)
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1-4. DNA Nanostructure (1) – Junction –
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1-5. DNA Nanostructure (2) – DNA Origami –
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Contents
1. Introduction
- What is DNA nanotechnology?
- DNA origami
2. Previous Studies on DNA Computers and
Winfree’s Enzyme-Free Nucleic Acid Logic Circuits
Seelig, G.; Soloveichik, D.; Zhang, D. Y.; Winfree, E.
Science 2006, 314, 1585.
3. Diverse and robust molecular algorithms using
reprogrammable DNA self-assembly (main topic)
Woods, D.; Doty, D.; Myhrvold, C.; Hui, J.; Zhou, F.; Yin, P.;
Winfree, E. Nature 2019, 567, 366.
![Page 10: Application of DNA self-assemblyinoue/assets/img/archive-pdf/190707...Application of DNA self-assembly “from origami to computer” 2019/07/13 Akira Hirose Contents 1. Introduction](https://reader034.fdocuments.in/reader034/viewer/2022042220/5ec666ab2a5b1b797e2aa000/html5/thumbnails/10.jpg)
2-1. Dawn of DNA-based Computing
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2-2. Development of DNA-based Computing
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2-3. Prof. Erik Winfree
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2-4. Enzyme-Free DNA Logic Circuits (1)
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2-5. Enzyme-Free DNA Logic Circuits (2)
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Contents
1. Introduction
- What is DNA nanotechnology?
- DNA origami
2. Previous Studies on DNA Computers and
Winfree’s Enzyme-Free Nucleic Acid Logic Circuits
Seelig, G.; Soloveichik, D.; Zhang, D. Y.; Winfree, E.
Science 2006, 314, 1585.
3. Diverse and robust molecular algorithms using
reprogrammable DNA self-assembly (main topic)
Woods, D.; Doty, D.; Myhrvold, C.; Hui, J.; Zhou, F.; Yin, P.;
Winfree, E. Nature 2019, 567, 366.
![Page 16: Application of DNA self-assemblyinoue/assets/img/archive-pdf/190707...Application of DNA self-assembly “from origami to computer” 2019/07/13 Akira Hirose Contents 1. Introduction](https://reader034.fdocuments.in/reader034/viewer/2022042220/5ec666ab2a5b1b797e2aa000/html5/thumbnails/16.jpg)
3-1. “Algorithmic” Self-Assembly
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3-2. Previous Work: DNA Sierpinski Triangles (1)
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3-3. Previous Work: DNA Sierpinski Triangles (2)
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3-4. “Reprogrammable” and Single-Stranded Tile
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3-5. Approaches toward Reducing Errors
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3-6. Conception of Algorithm Design
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3-7. Design of Circuits and Logic Gates
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3-8. Design of Each Single-Stranded Tile
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3-9. Experimental Protocol
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3-10. Final Analysis by Atomic Force Microscope
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3-11. Randomized Algorithm Using Self-Assembly
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3-12. Realized Algorithms by 6-bit IBC Tile Set
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Summary
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Appendix
29
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Determination of Reaction Temperature