Appendix E Page 1 29 - University of Toronto T-Space · 2013. 11. 7. · Bsx Klhdc8a Barx2 Dsp Cry1...
29
Appendix E Page 1 of 29 PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12 (953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets) 0610040J01Rik 0610012H03Rik 4930524B15Rik 0710005M24Rik 0610038D11Rik H2‐T3,H2‐Tw3 1300013J15Rik 1200009O22Rik 2310014L17Rik 9330182L06Rik 1100001H23Rik 1110021L09Rik 0610008C08Rik 1700011H14Rik 1300007F04Rik 2410004A20Rik Ace 1110018M03Rik 1110034A24Rik 1110017D15Rik 1700016K19Rik 1700001O22Rik 6530418L21Rik Arhgap29 1300014I06Rik 1500002O20Rik 1110020C03Rik 1700023E05Rik 1700019N12Rik 9030224M15Rik Axin2 1600015H20Rik 1700012A16Rik 1190002H23Rik 2010109I03Rik 1810031K17Rik 9030418K01Rik BC038286 1700008P20Rik 2010001M09Rik 1200002N14Rik 4930583H14Rik 2310010M24Rik 9130213B05Rik Cav2 1700024D23Rik 2010317E24Rik 1700003M02Rik 4931408C20Rik 2600011E07Rik A2bp1 Cdh3 2010001J22Rik 2300002D11Rik 1700025G04Rik 4933434E20Rik 2810003C17Rik AI427515 Cdkn2a 2310005P05Rik 2310047D13Rik 1700045I19Rik 7530404M11Rik 2810022L02Rik AW049604 Ddit4l 2310045A20Rik 2310076L09Rik 2010002N04Rik 9130211I03Rik 2810030E01Rik Aard Dmgdh 2510009E07Rik 2410018C20Rik 2210010L05Rik AA467197 4631416L12Rik Abhd9 E130319B15Rik 2600010E01Rik 2900046G09Rik 2410016O06Rik Aadat 4833424O15Rik Acan Egr1 2610206B13Rik 4733401H18Rik 2610018G03Rik Abca5 4921515J06Rik Accn2 Eml1 2810046M22Rik 4931440F15Rik 2610109H07Rik Agbl2 4931408A02Rik Accn4 Fgfbp3 2810432L12Rik 4933426M11Rik 2610204M08Rik Amfr 6030419C18Rik Acot5 Foxj2 2900006F19Rik 5430433E21Rik 2610528K11Rik Ankra2 6230409E13Rik Acvrl1 Hivep3 2900093B09Rik 5430433G21Rik 2810439F02Rik Ankrd15 6330406I15Rik Amigo1 Icam5 3110004L20Rik 6230427J02Rik 2810457I06Rik Ap2b1 6330500D04Rik Amn Kcnab3 3732412D22Rik 8430415E04Rik 2900041A09Rik Arhgap10 6330503C03Rik Ank1 Lrrc4 4631426J05Rik 8430419L09Rik 3110045G13Rik Arhgap19 6330514A18Rik Apba1 Lrrc8c 4632411J06Rik 9430020K01Rik 4632417D23Rik Arsj 6330527O06Rik Apcdd1 Mal2 4732435N03Rik 9630050M13Rik 4831426I19Rik Atp7b 6332401O19Rik Apln Marveld3 4833446K15Rik A230065H16Rik 4921504I05Rik B3galtl 9030425E11Rik Aqp3 Nkx3‐1 4921507P07Rik AI118078 4921510H08Rik BC017647 9030611O19Rik Areg P2rx5 4922505E12Rik AI464131 4922503N01Rik BC022651 A830053O21Rik Arhgap20 Pgk1 4930506M07Rik AK220484 4931429I11Rik BC039093 A830059I20Rik Arhgap26 Plcb1 4930511J11Rik Abhd5 5031414D18Rik BC057371 A930038C07Rik Arl4c Prkcq 4930589M24Rik Abhd8 5430407P10Rik BC057552 AB041550 Arntl Pxdn 4931406I20Rik Acad11 5730469M10Rik Baiap2l1 AI593442 Arpm1 Rora 4933404M02Rik Acot1 5730593N15Rik Bcl6b AI595406 Atp11a Sep‐08 4933416C03Rik Acot6 6330403A02Rik Brpf1 AI851790 Atp1b2 Sesn1 4933417E01Rik Adad1 6330442E10Rik Cacng2 AU042651 Atp2a3 Slc9a5 4933428M03Rik Adam11 6330512M04Rik Car8 Summary of Venn Diagram in Figure S3
Transcript of Appendix E Page 1 29 - University of Toronto T-Space · 2013. 11. 7. · Bsx Klhdc8a Barx2 Dsp Cry1...
-
Appendix E Page 1 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
0610040J01Rik 0610012H03Rik 4930524B15Rik 0710005M24Rik 0610038D11Rik H2‐T3,H2‐Tw3 1300013J15Rik1200009O22Rik 2310014L17Rik 9330182L06Rik 1100001H23Rik 1110021L09Rik 0610008C08Rik 1700011H14Rik1300007F04Rik 2410004A20Rik Ace 1110018M03Rik 1110034A24Rik 1110017D15Rik 1700016K19Rik1700001O22Rik 6530418L21Rik Arhgap29 1300014I06Rik 1500002O20Rik 1110020C03Rik 1700023E05Rik1700019N12Rik 9030224M15Rik Axin2 1600015H20Rik 1700012A16Rik 1190002H23Rik 2010109I03Rik1810031K17Rik 9030418K01Rik BC038286 1700008P20Rik 2010001M09Rik 1200002N14Rik 4930583H14Rik2310010M24Rik 9130213B05Rik Cav2 1700024D23Rik 2010317E24Rik 1700003M02Rik 4931408C20Rik2600011E07Rik A2bp1 Cdh3 2010001J22Rik 2300002D11Rik 1700025G04Rik 4933434E20Rik2810003C17Rik AI427515 Cdkn2a 2310005P05Rik 2310047D13Rik 1700045I19Rik 7530404M11Rik2810022L02Rik AW049604 Ddit4l 2310045A20Rik 2310076L09Rik 2010002N04Rik 9130211I03Rik2810030E01Rik Aard Dmgdh 2510009E07Rik 2410018C20Rik 2210010L05Rik AA4671974631416L12Rik Abhd9 E130319B15Rik 2600010E01Rik 2900046G09Rik 2410016O06Rik Aadat4833424O15Rik Acan Egr1 2610206B13Rik 4733401H18Rik 2610018G03Rik Abca54921515J06Rik Accn2 Eml1 2810046M22Rik 4931440F15Rik 2610109H07Rik Agbl24931408A02Rik Accn4 Fgfbp3 2810432L12Rik 4933426M11Rik 2610204M08Rik Amfr6030419C18Rik Acot5 Foxj2 2900006F19Rik 5430433E21Rik 2610528K11Rik Ankra26230409E13Rik Acvrl1 Hivep3 2900093B09Rik 5430433G21Rik 2810439F02Rik Ankrd156330406I15Rik Amigo1 Icam5 3110004L20Rik 6230427J02Rik 2810457I06Rik Ap2b16330500D04Rik Amn Kcnab3 3732412D22Rik 8430415E04Rik 2900041A09Rik Arhgap106330503C03Rik Ank1 Lrrc4 4631426J05Rik 8430419L09Rik 3110045G13Rik Arhgap196330514A18Rik Apba1 Lrrc8c 4632411J06Rik 9430020K01Rik 4632417D23Rik Arsj6330527O06Rik Apcdd1 Mal2 4732435N03Rik 9630050M13Rik 4831426I19Rik Atp7b6332401O19Rik Apln Marveld3 4833446K15Rik A230065H16Rik 4921504I05Rik B3galtl9030425E11Rik Aqp3 Nkx3‐1 4921507P07Rik AI118078 4921510H08Rik BC0176479030611O19Rik Areg P2rx5 4922505E12Rik AI464131 4922503N01Rik BC022651A830053O21Rik Arhgap20 Pgk1 4930506M07Rik AK220484 4931429I11Rik BC039093A830059I20Rik Arhgap26 Plcb1 4930511J11Rik Abhd5 5031414D18Rik BC057371A930038C07Rik Arl4c Prkcq 4930589M24Rik Abhd8 5430407P10Rik BC057552
AB041550 Arntl Pxdn 4931406I20Rik Acad11 5730469M10Rik Baiap2l1AI593442 Arpm1 Rora 4933404M02Rik Acot1 5730593N15Rik Bcl6bAI595406 Atp11a Sep‐08 4933416C03Rik Acot6 6330403A02Rik Brpf1AI851790 Atp1b2 Sesn1 4933417E01Rik Adad1 6330442E10Rik Cacng2AU042651 Atp2a3 Slc9a5 4933428M03Rik Adam11 6330512M04Rik Car8
Summary of Venn Diagram in Figure S3
-
Appendix E Page 2 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
AW125753 B3galt5 Tbc1d9 4933429E10Rik Aff1 9130019P16Rik Cd244AW544981 BC022623 Tdrd1 5730410E15Rik Agpat9 9530066K23Rik Chrdl1AW548124 Barhl1 Tgfb1 5730557B15Rik Ahnak A830041P22Rik Cldn1Abcb4 Bcl2l11 Tgfbr1 5830467P10Rik Ak3l1 A930008G19Rik Cngb3Abhd7 Bcr Trpm6 6030405A18Rik Akap13 A930034L06Rik CopgAbtb2 Bik Usp25 6330505N24Rik Ankrd27 AA407270 Cox4i1Ache Brsk2 Vegfc 6430502M16Rik Ankrd34a AI836003 Cox8cAcot3 Btn1a1 6430517E21Rik Ankrd34b AW822216 Cplx2
Adamts1 C130038G02Rik 6430550H21Rik Apold1 Aatk Cpxm2Adamts17 C130060K24Rik 6430706D22Rik Arhgap24 Abca1 Crisp4Adamts19 Cadm1 6720416L17Rik Arhgap9 Abca3 Cyp2c55Adamts2 Camk2n1 7420416P09Rik Arhgdig Abcc3 Cyp2j13Adamts7 Cap2 9130008F23Rik Arhgef7 Abcc8 Cyp2r1Adamts8 Casp8 9430077A04Rik Arid3c Abhd14b Cyp4x1Adcy1 Cbln2 9630019K15Rik Arrb1 Abhd3 D10Bwg1379eAdcy3 Ccdc3 9630031F12Rik Ass1 Acot12 Dbndd1Adcy5 Cd248 9930013L23Rik Atad2b Acss1 Ddx39Adcy7 Cd34 A030009H04Rik Atp2b1 Adamts16 Dock11
Adcyap1r1 Cdh7 A130092J06Rik Aven Adcy2 Drd2Adm Cftr A230097K15Rik B230120H23Rik Adcy9 Dtx4
Adora2a Cidea A230106N23Rik B230396O12Rik Adcyap1 E330009J07RikAdra1a Cited4 A330008L17Rik B3gnt5 Adrb2 Edg1Adra2a Clip4 A330019N05Rik B4galnt4 Adrb3 Edn1Adra2b Cnnm4 A430107O13Rik B4galt4 Afap1l1 Ehd3Adra2c Col23a1 A530088I07Rik B630019K06Rik Agtpbp1 Epb4.9Adrb1 Col24a1 A630077B13Rik B830045N13Rik Agtr1a Etv2Aebp1 Col8a2 A830073O21Rik Bahcc1 Aldh1l2 Eya1Aff2 Col9a3 A930001M12Rik Baiap2 Aldh5a1 Fbln5
Aldh1a2 Creg1 A930017N06Rik Batf3 Als2cl Fgf18Alx3 Crim1 A930021C24Rik Bhlhb2 Amph Fndc3bAlx4 Cuedc1 AA407452 Blvrb Ankrd9 Foxa3
Amigo2 Cxcl5 AB041803 Bmpr2 Anks6 Foxp4Ank Cygb AF529169 Bpil3 Apoa5 Gdpd1
-
Appendix E Page 3 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Ankrd43 D430039N05Rik AI314180 Brunol6 Arhgef17 Gkap1Ankrd56 Dact1 AI427122 C76566 Arl6 Gprin3Ankrd58 Dcdc2a AI646023 C79267 Armcx3 Grem2Apba2 Ddah1 AW146242 Cacna1a Asah3l GusbApbb1ip Des Abcb9 Cacna1s Asahl HhatAqp5 Dusp15 Abcg4 Camk2n2 Atxn1 Hist1h2aaAr Dusp9 Abhd6 Caskin1 B3galnt1 Hist1h2baArg2 E130203B14Rik Accn1 Ccin BC011209 Hmha1
Arhgap6 EG240055 Adam12 Ccno BC049816 Hnrpa2b1Arsb Edn3 Adam33 Cd109 BC052328 Hnrph1Arsi Eid1 Adamts15 Cdk10 BC072620 Igf2bp2Arx Elovl7 Adamts18 Cdk8 BC089491 Igfbp7Ascl1 Fmnl1 Adamts20 Cebpb Bcat1 Itga4Ascl2 Fndc5 Adamts3 Centa2 Bmp2k Itgb2Atoh1 Foxp2 Adamts5 Cgrrf1 Bmp8a Kcna4Atoh7 Freq Adarb1 Chd5 Bmyc Klf5Atp10a Frmpd1 Adarb2 Chd7 Btbd14a Klrd1Atp12a Fxyd7 Adcy8 Chrm1 C130074G19Rik LipaAtp2b3 Galr2 Adora1 Chsy3 C330005M16Rik Lrrtm3Avp Gchfr Adora2b Cideb C530024P05Rik Ltbp1
Avpr1a Gipc3 Adra1b Cldn10 C77370 Map2k1ip1B230399E16Rik Gli3 Adra1d Clec2l Cacna1b Map3k8
B2m Gng12 Afap1 Clgn Cadm3 Map4k4B3gat2 Gpc1 Aff3 Cnnm3 Capn2 Mcl1B4galnt1 Gpr135 Ak5 Cnrip1 Car12 Me3
B930011P16Rik Gpr158 Alcam Cntln Cartpt Megf10BC004044 Gpr26 Aldh1a3 Coro6 Cbs Mfsd1BC021891 Gpr84 Alk Cpm Cbx2 Mll3BC030476 Gprc5c Alox12 Csnk2a1 Ccdc96 MmdBC030500 Grip1 Alox15 Ctage5 Ccna1 Mmp7BC038822 Habp4 Alox5 Cxcl1 Cd200 Morc4BC052055 Heyl Ankrd38 Cybrd1 Cdc14a Mpp5BC061194 Hoxd4 Ankrd44 Cyp26c1 Cds1 Mppe1
-
Appendix E Page 4 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Bace2 Hpcal1 Antxr1 D12Ertd551e Cdx1 MpzBach2 Hrasls Antxr2 D18Ertd653e Celsr3 Mtus1Bai1 Hrasls5 App D330027H18Rik Chga Myh11Bai2 Hrh1 Astn2 D8Ertd82e Chl1 Nfxl1Barhl2 Hrh3 Atf3 Dab2 Chpt1 Nhlrc1Barx1 Hs3st6 Atoh8 Dapk1 Chrna3 NmiBcan Hsf5 Atp2b2 Dcbld1 Chrna4 Olfr1341Bcl11a Hspa4l Atp6v1c2 Dclk1 Clec14a Osgin2Bcl2 Htr4 Atp8b1 Dclk3 Cmtm8 Pcsk1Bcorl1 Hunk Auts2 Ddef2 Cnfn Pdap1Bdnf Id2 Aytl1 Ddn Cnot6l Pef1Bhlhb3 Igf1r B230342M21Rik Defb25 Col9a2 Plcg2Bhlhb4 Insl3 B430119L13Rik Dennd2d Coro2b Plod2Bhlhb5 Kcnh1 B4galnt2 Depdc2 Cpd Plxdc2Bin1 Kcnj11 BC004853 Dgkk Cpe Pon2Bmi1 Kcnk1 BC029169 Dlk2 Cpn1 Ppm1eBmp2 Kcnk3 BC030477 Dlx6 Cpne5 Ppp3ccBmp3 Kcns1 BC043934 Dnajc22 Cpz Prom2Bmp4 Kcns2 BC062109 Dnmt3a Crim2 Rbm5Bmp6 Kif12 BC063749 Dok7 Crispld2 RelBmp8b Kit Bahd1 Donson Crtac1 Resp18Bmper Klhdc1 Bapx1 Dopey2 Crtc3 Rock2Bsx Klhdc8a Barx2 Dsp Cry1 Rpl22l1
Btbd11 Kndc1 Bcl11b Dusp5 Cryaa Rshl1Bves Krt18 Bcor Dusp7 Crygn Sall2
C030014K22Rik Lamc3 Bhmt2 Dux Cspg4 SctrC130090K23Rik Larp2 Bicc1 Dync1i1 Cthrc1 Scube2
C1ql1 Lemd1 Bmp1 E2f6 Ctsh Sertad3C1ql2 Lgi3 Bmp7 EG545758 Cyp27a1 Skap1C1ql3 Lor Bnc1 EG664805 Cyp46a1 Slc25a24C1ql4 Lpgat1 Boc Edem1 Cyp7b1 Slc27a3C1qtnf4 Lsamp Bok Efna1 Cys1 Slc7a11
C530028O21Rik Ltb Boll Eid2 Cyyr1 Smad3
-
Appendix E Page 5 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Cables1 Ltb4r2 Brunol4 Eif5 D030011O10Rik Smpdl3aCabp7 Ltbp3 Btbd4 Eif5a2 D330045A20Rik Smyd2Cachd1 Man2a1 C030003D03Rik Elfn1 D4st1 SnnCacna1i Matk C030014M07Rik Eml3 D5Ertd593e Sort1Cacna2d1 Mcam C130076O07Rik Enox1 D5Wsu178e Spc25Cacna2d2 Mctp1 C230094A16Rik Epb4.1l1 D930040M24Rik Sprr1bCacnb2 Mfap3l C78409 Epb4.1l3 D9Ertd280e Stat1Caln1 Mgll Cacna1d Eps15 Daam2 Stx3
Camk2d Mlf1 Cacna1e Erbb2 Dach2 Tbrg1Camk4 Mocos Cacna1g Ereg Dapk2 Tcam1Camkk1 Mpped1 Cacna1h Espn Dbx2 Tcba1Car10 Msi1 Cacna2d3 Etv3 Dcamkl1 Tcf3Car4 N28178 Cacnb3 Fads3 Dcamkl3 Tgfb1i1Car7 Nab2 Cacnb4 Far2 Ddx4 Tgif1Casp7 Nefh Cacng4 Fbln7 Dis3l Thbs1Casz1 Neurod1 Cadm2 Fbxo39 Dlgap4 Thyn1Cav1 Nope Cadps Fgf11 Dll3 Timp2Cbln1 Nrarp Cadps2 Fgfr4 Dnahc11 Tmem180Cbln4 P42pop Calb1 Fkbp1a Dnm3 Tmem35Cbr3 P4ha2 Calca Flt4 Dnmt3b TnrCbx4 Pacsin1 Calcr Fndc4 Doc2a Tram2Cbx8 Palm2 Camk1d Foxo1 Dock1 Trim7Cck Panx2 Camk2b Frat1 Dock4 Trpa1Cckbr Papolb Car11 Frmd6 Dpys Trpm7Ccr10 Paqr4 Car2 Fscn1 Dtx3l TsnaxCcr9 Pcdha1 Card10 Fsd1l E130112L23Rik Ube2l3Cd14 Pcdha10 Cart1 Fxyd1 EG215714 Ubtd2Cd24a Pcdha3 Casr Fzd9 EG331392 Ugt1a1Cd70 Pcdha4 Ccbe1 Galnt10 EG432939 Usp44Cd83 Pcdha5 Ccdc109b Gas2l1 EG633640 Utp18
Cdc42ep1 Pcdha9 Ccdc44 Gas2l2 Ece2 UvragCdh13 Pcdhga10 Ccdc85a Gcgr Ednra Vsnl1Cdh20 Pcdhga8 Ccnd1 Gckr Eef1a2 Xylt1
-
Appendix E Page 6 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Cdh4 Pcdhga9 Ccnd2 Gjd2 Efcbp1 Zbtb4Cdk5r2 Pcdhgb2 Ccnu Gjd3 Egfl6 Zfp192Cdkn1c Pcdhgb4 Cd302 Glcci1 Egln3Cdkn2c Pde1b Cd44 Glt8d4 Eif2c4Cdx2 Pde4a Cdc14b Gm1564 Eif4g3Cebpa Peg12 Cdc42ep3 Gm347 Elmod1Cebpd Perp Cdgap Gm50 Eltd1Cecr6 Pfn3 Cdh11 Gm705 Emid1Centg1 Plcxd3 Cdh2 Gm71 Emp2Ch25h Plscr4 Cdh22 Gm88 Eno2Chrd Plxna2 Cdh6 Gnaq Epha10Chrdl2 Ppapdc1a Cdh8 Gnat1 Epha3Chrna5 Prkar2a Cdkl1 Gng10 Epha8Chst11 Ptgdr Cdkn2b Gng11 Ephb2Chst2 Ptpn14 Cdx4 Golga4 Ero1lbChst3 Ptprz1 Celsr2 Gpr182 Ets1Chst7 Pygo1 Chat,Slc18a3 Gpr56 EvlChsy1 Rap1gap Chd3 Grrp1 F3Cilp2 Rapgef4 Chrm3 Grwd1 Fabp5Cited1 Rasgef1c Chst8 Gse1 Fads6Clcf1 Rasl11a Chx10 Gsn Fbln2Cldn23 Rgs11 Clstn2 Gsx1 Fbxl10Cldn3 Rgs8 Cnksr2 Gsx2 Fez1Cldn5 Rhoj Cobll1 H1f0 Ffar3Clic6 Rin3 Col12a1 H2‐Bl Fgf14Clstn1 Rnf128 Col13a1 H2‐D1 Fgfr1Cnih3 Ror1 Col19a1 H2‐K1 Fgfrl1Cnnm1 Rreb1 Col2a1 H2‐Q1 Fgl2Cnr1 Rspo4 Col4a1 H2‐Q10 Fmn2Cntn4 Rtn4r Col4a4 H2‐Q2 Foxred2Cntnap1 Rufy4 Corin H2‐Q6 Fstl1Coch Scn1b Cpeb1 H2‐Q7 Fut7
Col14a1 Scn8a Cpne8 H2‐Q8 Fxyd5
-
Appendix E Page 7 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Col15a1 Scnn1b Creb3l1 Hcn1 GabrdCol25a1 Scrt1 Creg2 Hcn2 Gabrg3Col27a1 Sdc3 Crhbp Hectd2 GabrqCol4a2 Sema3c Crym Heg1 GalCol4a3 Sema7a Csf1 Hes6 Galnt6Col5a1 Sep‐05 Csmd1 Hhex Galnt7Colec12 Serf1 Cttnbp2 Hhipl1 Galr3Commd3 Sfrp1 Cx3cl1 Hip1r Garnl4Comp Shank3 Cyp24a1 Hivep1 Gch1Cpeb2 Slc12a5 Cyp27b1 Hlx Gfod1Cpne2 Slc22a17 Cyp4v3 Hmcn2 Gfra3Cpne7 Slc36a4 D11Bwg0517e Hmgb3 GhrCrabp1 Slc7a10 D1Ertd622e Hnf1b Gjb6Crhr1 Slco2a1 D230005D02Rik Hspa1b Gli2Crlf1 Sox8 D3Bwg0562e Htr1d Glp1rCryba2 Speg D430041D05Rik Il10rb GlrbCtdspl Spock2 D530005L17Rik Il13 Gm691Ctnnd2 Ssbp2 D630044L22Rik Il17ra Gm784Cxcl12 St3gal5 D830007B15Rik Inha Gpr139Cxcl14 Stat5a D930049A15Rik,Zmiz1 Inhba Gprin1Cxcl16 Susd4 Dach1 Iqsec2 Grid2ipCxcr4 Syt7 Dbc1 Isg15 Grik4Cxxc4 Tacr1 Degs2 Isoc1 Grm1Cyp1b1 Tacr3 Dfna5h Itga9 Gtf2a1lfCyp26a1 Tap1 Dgat2 Itgb4 Gucy1a3Cyr61 Tbx3 Dgki Jak2 Gypc
D230039L06Rik Tdrkh Disc1 Jdp2 H2afy2D330017J20Rik Tgfbi Dmbx1 Jund Has2D930020B18Rik Tmem117 Dmn Kcna7 Hba‐x
Dab1 Tmem158 Doc2b Kcng4 Hey2Dbndd2 Tmem171 Dock3 Kcnj12 HhipDbx1 Tmem59l Dok5 Kcnn2 Hormad1Dhh Tnfaip8 Dok6 Kdelr3 Hpse
-
Appendix E Page 8 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Dhrs3 Trim62 Dpf3 Kif26a Htr5aDio3 Tshr Dpp10 Kif3a Ibrdc2Dkk1 Tshz2 Dpp4 Kiss1 Id1Dkk2 Ttc7 Dpysl5 Klf4 Igf2bp3Dlgap2 Tuba8 Dscam Klhdc2 Igsf21Dlk1 Vgf Dscr6 Klhl15 Ikzf4Dll1 Vipr2 Dtx1 Krt8 Il11Dll4 Wdr40b Duox2 Krt83 Il12rb2Dlx1 Wdr40c Duoxa1 L3mbtl4 Il7Dlx2 Wdr54 Dusp14 Larp6 Inpp4aDlx3 Wnt9a E130306M17Rik Lgals3 InsrrDlx4 Zadh2 E130309F12Rik Limch1 Iqsec3Dlx5 Zdhhc2 E130310K16Rik Loxl3 IslrDmrt1 Zfp354b E330016A19Rik Lpar3 Itga1Dmrt2 Zfp579 EG277333 Lrg1 Itga2Dmrt3 Zfp697 EG328479 Lrrc10 Itga8Dmrta1 Zfp804a EG434280 Lrrc26 Jag1Dmrta2 Zic5 EG545861 Lrrfip1 Kcnab1Dnaja4 Ebf3 Lrrk2 Kcnab2Dnajb3 Edaradd Lyl1 Kcnb1Dock8 Edg2 Malt1 Kcng1Dok1 Edg3 Mamld1 Kcnh5Dpp6 Edg7 Map6d1 Kcnj2Dpysl4 Edg8 Mapk14 Kcnj5Drd1a Ednrb Mapk15 Kcnk6Drd4 Eef2k Mar‐11 Kif21aDrd5 Efcbp2 Marcks Klhl22
Dscaml1 Efna5 Mbnl1 Klhl32Duoxa2 Efnb2 Mchr1 Klhl34Dusp2 Egfl9 Mdfic Krba1Dusp26 Egflam Mesp2 Krt4Dusp4 Eif4e3 Mgat4b Krt7Dysf Elovl4 Micall1 Lass6
-
Appendix E Page 9 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Dzip1l Emid2 Mmp14 Lhx3E030018N11Rik Emilin2 Mmp24 Lims2
EG622408 Endod1 Mnx1 Loxl2EG639653 Enpp1 Mt2 Lrig1
Ebf1 Entpd2 Mtmr10 Lrrc4bEbf2 Epha4 Muc5b Lrtm2Ebf4 Epha5 Mxi1 LycatEcel1 Epha6 Myl3 Magee1Edil3 Ephb1 Nap1l5 MallEfhd1 Epor Nav2 Man1c1Efna3 Esr2 Ncam2 Mapk12Efnb1 Esrrb Ngf Mapk8ip2Egfr Esrrg Ninj1 Mast1Egr2 Extl1 Nkx2‐1 Mesdc1Egr3 Eya4 Nkx2‐6 Mib1Egr4 Faah Nkx3‐2 Mid1
Emilin3 Fbn1 Notch2 MlphEmx1 Fbn2 Notum Mmd2Emx2 Fbp1 Npb Mod1En1 Fbxl7 Nrcam MrasEn2 Fbxo32 Nrxn2 Mtap7d2
Eomes Fgf10 Nsun7 Mtnr1bEpas1 Fgf12 Nt5c1a MycEpha7 Fgf13 Nt5m MylipEsam1 Fgf15 OTTMUSG00000008561 Myo5aEsx1 Fgfr2 OTTMUSG00000009974 MyocdEtnk2 Fhl2 OTTMUSG00000015750 Nav1Evx1 Fibcd1 OTTMUSG00000019524 NfascEvx2 Fli1 Olfm1 NhsFarp1 Flt1 Otud7a NmbrFat4 Flt3 Oxct2a NmuFev Foxo6 Oxct2b NovFezf2 Frem2 Pard6g Nrxn1
-
Appendix E Page 10 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Fgf16 Frmd4b Pax4 Nuak2Fgf2 Frzb Pbx4 OTTMUSG00000000934Fgf20 G630014P10Rik Pcdha2 Olfml2bFgf3 Gab1 Pcdhb17 Olfr95Fgf5 Gabbr2 Pcdhb19 Osbpl5Fgf8 Gabra1 Pcdhb20 Pak6Fgf9 Gabra2 Pcdhb21 Paqr8Fgfr3 Gabra4 Pcdhb3 Parp9Fhod3 Gabra5 Pcdhb5 Pcdhb22Fjx1 Galnt14 Pcdhgb8 Pcdhga4Flnc Galnt3 Pcsk2 Pcdhga7Flrt2 Galntl4 Pdia2 Pde11aFosl1 Galr1 Pds5b Pde8bFosl2 Gas6 Pdzd3 Pdia5Foxa1 Gata3 Pex6 Pdlim2Foxa2 Gata4 Pgls Peg10Foxb1 Gatm Phf13 Pfkfb3Foxb2 Gbx1 Phlda1 PgfFoxc1 Gda Phldb3 Pgm5Foxc2 Gem Phlppl Phactr1Foxd1 Gfra1 Phpt1 Phf19Foxd2 Gja3 Pim1 Phldb2Foxd3 Gjc1 Pitpnm1 PhyhipFoxd4 Glis3 Plcl1 Pik3cdFoxe1 Gm628 Plk2 Pip5k2aFoxe3 Gm672 Plk3 PkiaFoxf1a Gm879 Pmaip1 Plec1Foxf2 Gm960 Pnma2 Plekhg6Foxg1 Gnai1 Pnmal2 Plxna1Foxi2 Golph4 Ppapdc2 PnckFoxl1 Gpc3 Pparg PnmtFoxl2 Gpr126 Ppfia2 Pnpla3Foxq1 Gpr149 Ppp1r16b Podxl2
-
Appendix E Page 11 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Fras1 Gpr176 Ppp1r3d PogkFrmd3 Gpr37 Ppp1r9b Ppargc1bFst Gpr64 Ppp3ca PplFstl4 Gprc5b Prdm12 Pqlc1Fut4 Gramd1b Prdx5 Prkag3Fzd1 Grb10 Prm1 Prkar2bFzd10 Grb14 Prm2 PrlrFzd2 Grhl2 Prm3 Prmt8Fzd4 Gria2 Prpf4b Prrt1Fzd6 Gria3 Prph Psmb8Fzd8 Grik1 Prr18 Pstpip2Gab2 Grik2 Prtg Ptchd2Gabrb1 Grin2a Psmb9 PtgfrGad1 Grin2b Ptger1 PtgirGad2 Grin2c Ptpn9 Ptgs1
Gadd45g Grm3 Ptpra Ptgs2Galnt12 Grm4 Rab2a Ptpn18Galnt13 Grm8 Rab3b PtprrGalntl1 Gsh1 Raet1a PtprsGas1 Gsh2 Rai1 PvalbGata2 Gucy1b3 Ralyl QpctGata5 Gucy2e Ramp1 Qscn6Gata6 Gulp1 Ramp2 Rab11fip4Gbx2 Hcrtr1 Rap2b Rab15Gdf10 Hcrtr2 Rassf10 Rab32Gdf6 Hdgfrp3 Raver2 Rab36Gdf7 Hecw1 Rbm35b Rab38Gdnf Hecw2 Rcor1 Rac3Gdpd5 Hey1 Rdh10 Rapgef3Gfi1 Hlf Rhob RarbGfra2 Hlx1 Rimbp3 Rasd1Gfra4 Hlxb9 Rims2 Rasl12Ghsr Hmga2 Ripply2 Rfxap
-
Appendix E Page 12 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Gjb2 Hmgn3 Ripply3 RgnefGldn Hnt Rnf103 Rgs7Glis1 Homer2 Rnf130 Rhbg
Glt25d2 Hoxa3 Rnf39 RhcgGm1337 Hpcal4 Rnf8 Rhobtb3Gm1568 Hpgd Rom1 Rims1Gm1673 Hrh2 Rpl7 Ripk3Gm266 Hs3st3b1 Rps6ka4 Rnd1Gm996 Hs6st2 Rragd Rnf144Gna14 Hspb2 Rrs1 Robo1Gnal Htr1f Rtkn Rtn1Gnas Htr5b Runx1t1 Rtn4rl2Gng4 Htr6 Rusc2 Rusc1Gp1bb Htr7 Rxra Scnn1gGp5 Htra4 S1pr1 SctGpc5 Ica1l Sccpdh Serinc2Gpc6 Igfbp5 Scmh1 Sfrp4Gpm6b Igfbpl1 Scn3b SgcbGpr101 Ikzf3 Sdk1 Sgip1Gpr12 Il10ra Sep‐15 Sh2b2Gpr120 Il28ra Sh3pxd2b Sh3bp5Gpr124 Il6ra Sh3rf3 Sh3gl2Gpr150 Irak3 Shank2 Slc13a5Gpr156 Irs1 Shisa2 Slc17a6Gpr177 Irs4 Shisa3 Slc18a2Gpr27 Isl1 Shmt2 Slc22a21Gpr45 Itgb8 Six5 Slc25a31Gpr50 Itpr2 Slc10a4 Slc30a4Gpr6 Jam3 Slc17a7 Slc35e4Gpr83 Jazf1 Slc18a3 Slc38a3Gpr88 Jph1 Slc1a1 Slc40a1Grem1 Jundm2 Slc25a4 Slitrk2Grid1 Kcna5 Slc35f2 Smpd3
-
Appendix E Page 13 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Grid2 Kcnc4 Slc35f3 Snx26Grik3 Kcne3 Slc6a1 Sorbs3Grm7 Kcng3 Slc9a3r1 Sorcs1Grp Kcnj4 Sned1 Sorcs2Gsc Kcnj6 Snx24 Sox13
H2‐Ab1 Kcnk12 Socs1 Spink2Hand1 Kcnk2 Socs7 Spnb4Hand2 Kcnk9 Sost Spsb1Hapln4 Kcnma1 Sprn SrrpHas3 Kcnmb4 Spry1 St6gal1Hcn4 Kcnq1 Srf St8sia1Helt Kcnq2 Srrd StacHes2 Kcnq3 Stambpl1 Stard13Hes5 Kcnq4 Stard10 Steap3Hes7 Kcnq5 Stbd1 Stk32bHic1 Kcns3 Stx17 Stk39
Hivep2 Kctd1 Susd5 Stra6Hmx1 Kctd8 Sync Stx4aHmx2 Kdr Syne2 Sycp2Hmx3 Kif1a Synpo Syt13Hoxa1 Klhl1 Tfrc Taf9bHoxa10 Klhl14 Tgif2 Tanc2Hoxa11 L3mbtl3 Thrb Tcerg1lHoxa13 LOC545291 Tiam2 Tekt2Hoxa2 LOC547127 Tifa Tekt4Hoxa4 LOC625638 Tiparp Tex11Hoxa5 Lamb1‐1 Tle2 Tfpi2Hoxa6 Lats2 Tmem102 Thbs4Hoxa7 Leprel1 Tmem151a Timp3Hoxa9 Lgi2 Tmem20 Tll2Hoxb1 Lgr5 Tmem215 Tmcc2Hoxb13 Lgr6 Tmod1 Tmco6Hoxb2 Lhx6 Tnfrsf13c Tmed8
-
Appendix E Page 14 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Hoxb3 Lhx8 Tnfsf13b Tmem108Hoxb4 Lipg Tnp2 Tmem151Hoxb5 Lmo1 Tob1 Tmem179Hoxb6 Lmx1b Tpm2 Tmem26Hoxb7 Lox Tppp Tmem41aHoxb8 Loxl1 Tram1l1 Tmem45bHoxb9 Lrat Trib1 Tmem9bHoxc10 Lrig3 Trim58 Tmod2Hoxc11 Lrp1b Trim65 Tox3Hoxc12 Lrp2 Trp53i13 TrfHoxc13 Lrp4 Tsc22d2 Trim14Hoxc4 Lrrc33 Ttc39a Trim36Hoxc5 Lrrc3b Ttc39c Trim44Hoxc6 Lrrc62 Tubb3 Trim50Hoxc8 Lrrc7 Tusc1 Trim9Hoxc9 Lrrk1 Ube2m Trp53i11Hoxd1 Lta Ube2q2 Trpv4Hoxd10 Ltbp2 Ubtd1 Tspan11Hoxd11 Lypd1 Uhrf1bp1 Tspan17Hoxd12 Lyzl4 Uhrf2 Tspan18Hoxd13 Mal Unc13b Tssk3Hoxd3 Mamdc1 Unc5a Ttc22Hoxd8 Man1a Uncx Ttc9bHoxd9 Mansc1 V1rb3 Ucp1Hr Mapk11 Vstm2a Ugcgl2Hrk Mar‐03 Vstm2b Ugt8a
Hs3st2 Matn4 Vstm2l Vav1Hs3st3a1 Mdfi Vsx2 Whsc2Hs3st5 Mdga1 Wac Wif1Hs6st3 Mds1 Whdc1 Wipf1Hsd17b1 Megf9 Whsc1 Wnk4Hsf4 Meis1 Wscd1 Xkr4Hspa2 Mfsd2 Wscd2 Xkr7
-
Appendix E Page 15 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Htr1a Mfsd4 Ybx2 Zeb2Htr1b Mical2 Zar1 Zfp248Htr2c Mkx Zc3hav1l Zfp423Htra1 Mllt3 Zdhhc22 Zfp575Id3 Mmp16 Zeb1 Zfp9Id4 Mmp25 Zfhx3 Zim1Ier5 Mmp28 Zfp281 Zpbp2Igf2 Mmp9 Zfp296
Igfbp3 Mogat1 Zfp318Igfbp4 Mos Zfp36l1Igfbp6 Mrg1 Zfp593Ihh Myb Zfp612Ikzf1 Mycl1 Zfp623Il15ra Nab1 Zfp641Il1rapl2 Ncald Zfp664Il1rl2 Ncam1 Zfp703Il20ra Ndrg1 Zfp827Ina Nebl Zfyve21
Inhbb Nell2 Zkscan16Insm1 Nexn Zmiz1Insm2 Nfatc1 Zswim5Irf2 Nfatc2Irf4 NfibIrf5 Nfil3Irf8 NfixIrx1 NgefIrx2 NgfbIrx3 NinIrx4 Nkd2Irx5 Nlgn1Irx6 Nmnat2Isl2 Nol4Islr2 Npal2
-
Appendix E Page 16 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Itga11 Npas1Itga7 NpntItgb3 Npr1Itpka Npr3Itpkb NptxrJph3 Npy5rJph4 Nr2e1Jun Nr5a1
Kazald1 Nrg3Kbtbd5 Nrip3Kcna1 Nsg1Kcna2 Ntf3Kcna3 Ntn1Kcna6 Ntng1Kcnc1 Ntrk3Kcnc2 Nxf2Kcnd2 Nxph2Kcnd3 OTTMUSG00000006683Kcne1l OafKcnf1 OclnKcnh3 Olfm2Kcnj3 Oprd1Kcnj8 Osbp2Kcnk13 OsmrKcnk15 Ovol1Kcnk4 Ovol2Kcnt1 OxtrKcnv1 P2ry2Kctd12 Pag1Khdrbs2 Parp12Kirrel3 Parp8Kitl Pax3Kl Pax5
-
Appendix E Page 17 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Klhl23 Pax6Klrg2 Pax7
Kremen2 Pax8Ky Pbx3Lad1 Pcdh1Lancl3 Pcdh18Lbh Pcdha11Lbx1 Pcdhac1Lbx2 Pcdhga12
Lbxcor1 Pcdhgb1Lef1 Pcdhgc3Lepr Pcolce2Lfng Pcsk9Lhfp Pde4dipLhfpl2 PdgfbLhfpl3 Pdzrn3Lhx1 Per2Lhx2 Pftk1Lhx5 Phldb1Lhx9 Pik3ap1Lin7a Pitpnm3Lmo2 Pitx3Lmx1a Pknox2Lonrf3 Pkp1Lphn3 PlauLpl Pld5Lrfn2 PllpLrfn5 Plxna4Lrp8 Plxnc1Lrrn1 Plxnd1Lrrn2 PodnLrrtm1 PodxlLtb4r1 Ppara
-
Appendix E Page 18 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Ltbr Ppp1r14cLtk Ppp1r3b
Luzp2 Ppp2r2bLy6h Prdm14Lyn Prdm16
Lysmd2 Prickle1Mab21l1 Prima1Mab21l2 Prkag2Maf PrkcmMafa Prkg1Mafb Prkg2
Map3k5 Prok2Mapt Prokr2
Mboat1 Prom1Mbp Prox1Mc4r Prph1Megf11 Prrx1Meox2 PtgisMesp1 PthlhMetrnl Pthr1Mfhas1 Pthr2Mixl1 Ptpn5Mlxipl PtprjMmp15 PtprmMmp17 PtprtMn1 PtpruMoxd1 PtrfMrc2 Pwwp2Msc Rab20Msx1 Rab27bMsx2 Rab31Msx3 Rab8bMtap6 Rasef
-
Appendix E Page 19 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Mycs Rasgrf2Myo16 Rasgrp1Myo5b Rassf2Myod1 Rassf5Myrip Rbm35aNags Rbm43Nat8l Rcsd1Nbl1 RelnNdn RergNefl RetNefm Rftn1Negr1 Rgl1Nell1 Rgl3Nes RgmbNeto1 Rgs10
Neurod2 Rgs17Neurog1 Rgs2Neurog2 Rgs20Neurog3 Rgs7bpNfe2l3 Ripk4Nfia Rnf152Ngb Ror2Nhlh2 RorbNkd1 Rspo2Nkx1‐2 Rspo3Nkx2‐2 Runx1Nkx2‐3 Ryr2Nkx2‐4 Sall3Nkx2‐5 Satb1Nkx2‐9 Satb2Nkx6‐1 Scara3Nkx6‐2 ScinNlrp6 Scn5a
-
Appendix E Page 20 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Nog Scube1Npas2 Sdk2Npas3 Sema3fNphs2 Sema6aNppc Serpine2Npr2 Sertad4Nptx1 Sez6lNptx2 Sgpp1Npy Sh3md4Npy2r Sh3px3Nr2f1 Shc3Nr2f2 Shc4Nr4a2 Siah2Nr4a3 Sidt1Nrgn Six3Nrk Slc16a11Nrn1 Slc16a12Nrp1 Slc16a14Nrp2 Slc16a2Nt5e Slc22a3Ntn2l Slc22a4Ntn4 Slc24a2Ntrk2 Slc25a21Ntsr1 Slc26a4Ntsr2 Slc27a2Nxph1 Slc2a13Nxph4 Slc41a2Odz4 Slc6a17Olfr94 Slc6a3Olig1 Slc7a14Olig2 Slc7a4Olig3 Slc7a8
Onecut1 Slc8a3
-
Appendix E Page 21 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Onecut2 Slco3a1Onecut3 Slit1Opcml Slmo1Osbpl6 Smad6Osr1 Smarcd3Osr2 Snap91Otop1 SncaOtp SnphOtx1 Sntb1Otx2 Sntg1Oxt SobpP2ry1 Sox6Pappa Spock1Paqr9 Spsb4Pard3b Srd5a2Parva SrmsPax1 Sstr5Pax2 St3gal1Pax9 St3gal6
Pcdh10 St6galnac5Pcdh11x St8sia2Pcdh17 St8sia4Pcdh7 St8sia6Pcdh8 Stac2Pcdha12 Stc2Pcdhac2 Stk32cPcdhga11 Stxbp5Pcdhgb5 Stxbp6Pcdhgb6 Susd3Pcdhgb7 Svep1Pcdhgc4 Sycp1Pde10a Sypl2Pde3a Syt10
-
Appendix E Page 22 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Pde3b Syt12Pde5a T2bpPde8a Tbc1d4Pdgfra Tbx18Pdx1 Tbx20Peli2 Tbx21Penk1 Tbx22Pfdn4 Tcf2Pgr Tcfap2a
Phlda2 Tcfap2ePhox2a Tdrd6Phox2b TenrPigz Tex12Pitx1 TgfaPitx2 Tgfb2Pkdrej Tgfbr2Pkib Tgfbr3Plagl1 Thy1Plcl2 Titf1
Plekhg3 Tll1Plekhh2 Tmem132dPlekhh3 Tmem163Plekho1 Tmem166Pmp22 Tmem16kPopdc3 Tmem46Pou3f1 Tmem56Pou3f2 Tmem63aPou3f3 Tmprss2Pou3f4 Tmtc1Pou4f1 Tnfaip8l3Pou4f2 Tnfrsf19Pou4f3 Tnfrsf1aPpm1h Tnfrsf8
-
Appendix E Page 23 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Ppm1l Tnfsf11Ppp1r1b Tnfsf9Ppp2r2c ToxPrdm13 Tpm1Prdm6 Traf5Prdm8 TrhdePrkcb1 Trib2Prkcdbp Trp73Prkce Trpc1Prkch Trpc4Prlhr Trpc5Prr15 Tsc22d3Prr16 Tshz1Prrx2 Tspan12Prrxl1 Tspan2Prss12 Tspan5Prss23 Tspan7Ptf1a Tulp1Ptger2 Unc5bPtger3 Unc5dPtger4 Uncx4.1Ptprb UstPtpre Vash2Ptpro VcanPtx3 Vstm2Punc Wbscr17Pvrl1 Wnk2Rab6b Wnt2Rai2 Wnt2b
Rasgrf1 Wnt3aRasl10a Wnt7aRax Wnt7b
Rbm24 Wnt9b
-
Appendix E Page 24 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Rbp4 Xtrp3s1Rbpjl Zbtb16Reep1 Zc3hav1Rem1 Zfp422Rfx4 Zfp469Rgag4 Zfp521Rgma Zfp533Rgs6 Zfp536
Rgs9bp Zfp608Rhbdl3 Zfyve28Rhobtb1 Zhx1Rnf150 Zic4Rprm Zmat4RprmlRradRspo1Rtn4rl1Rxfp3Rxrg
Samd14Samd4Scarf2Scn4bScube3Sdc1
Sema3dSema5aSema5bSema6dSep‐03Sez6
Sfmbt2Sfrp2
-
Appendix E Page 25 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Sfrp5Sgk3Sgpp2SheShhShox2
Shroom1Sim1Sim2SirpaSix1Six2Six6
Slc16a9Slc1a2Slc1a6Slc24a4Slc30a10Slc30a2Slc30a3Slc32a1Slc34a2Slc35d3Slc35f1Slc39a8Slc43a1Slc44a5Slc4a4Slc5a1Slc5a8Slc6a11Slc6a2Slc6a4
-
Appendix E Page 26 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Slc6a5Slc7a2Slc9a2Slc9a3Slit2Slit3Slitrk3Slitrk4Slitrk5Smad9Smarca2SmoSmoc2SncaipSncbSnx22Sorcs3Sox1Sox11Sox17Sox18Sox21Sox3Sox30Sox4Sox7Sox9Sp5Sp8Sp9Sphk1Spnb3Spock3
-
Appendix E Page 27 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Spon1Sstr1Sstr4St6gal2St8sia3St8sia5Syn2Syt16Syt2Syt6T
Tac1Tacstd2Tada1lTal1
Tbc1d1Tbr1Tbx1Tbx15Tbx2Tbx4Tbx5Tcf21
Tcfap2bTcfap2cTcfap2dTescThbdThpoThsd7bTigd5Tlx1Tlx2
-
Appendix E Page 28 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Tlx3Tm6sf1Tmcc3Tmeff2
Tmem132eTmem16eTmem178Tmem181Tmem28Tmem30bTmem54Tnfaip2Tnfrsf11aTnfrsf21TnxbTpbgTrim47Trpc6Tshz3Tub
Twist1Twist2Ube2j1UcnUnc5cVash1Vav3Vax1Vax2Vgll2VimVipr1Vldlr
-
Appendix E Page 29 of 29
PCL2 + EZH2 + SUZ12 PCL2 + EZH2 PCL2 + SUZ12 EZH2 + SUZ12 PCL2 EZH2 SUZ12(953 unique targets) (249 unique targets) (40 unique targets) (772 unique targets) (483 unique targets) (469 unique targets) (167 unique targets)
Summary of Venn Diagram in Figure S3
Vsx1Vwa2Vwc2Wdr8Wnt1Wnt10aWnt10bWnt11Wnt16Wnt3Wnt4Wnt5aWnt6Wt1
Zbtb7cZcchc16Zdhhc14Zfhx4Zfp36l3Zfp467Zfp503Zfp711Zfpm1Zfpm2Zhx2Zic1Zic2
Zmynd15Znrf4
