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APPENDICES酸化チタン(ナノ粒子、アナターゼ型)の...
Transcript of APPENDICES酸化チタン(ナノ粒子、アナターゼ型)の...
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酸化チタン(ナノ粒子、アナターゼ型)の ラットを用いた吸入によるがん原性試験報告書
試験番号:0883
APPENDICES
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(Study No. 0883)
APPENDICES APPENDIX 1-1 IDENTITY OF TITANIUM DIOXIDE APPENDIX 1-2 STABILITY OF TITANIUM DIOXIDE APPENDIX 2 AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS APPENDIX 3 ENVIRONMENTAL CONDITIONS OF INHALATION CHAMBER (CARCINOGENICITY STUDY GROUPS) APPENDIX 4 ENVIRONMENTAL CONDITIONS OF INHALATION CHAMBER (SATELLITE GROUPS) APPENDIX 5 METHODS, UNITS AND DECIMAL PLACE FOR HEMATOLOGY
AND BIOCHEMISTRY APPENDIX 6 METHODS, UNITS AND DECIMAL PLACE FOR CYTOLOGY
AND BIOCHEMISTRY OF BALF APPENDIX 7-1 CLINICAL OBSERVATION(INDIVIDUAL) : MALE APPENDIX 7-2 CLINICAL OBSERVATION(INDIVIDUAL) : FEMALE APPENDIX 8-1 BODY WEIGHT CHANGES(INDIVIDUAL) : MALE APPENDIX 8-2 BODY WEIGHT CHANGES(INDIVIDUAL) : FEMALE APPENDIX 9-1 FOOD CONSUMPTION CHANGES(INDIVIDUAL) : MALE APPENDIX 9-2 FOOD CONSUMPTION CHANGES(INDIVIDUAL) : FEMALE APPENDIX 10-1 URINARYSIS(INDIVIDUAL) : MALE APPENDIX 10-2 URINARYSIS(INDIVIDUAL) : FEMALE
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APPENDIXS (CONTINUED) APPENDIX 11-1 HEMATOLOGY(INDIVIDUAL) : MALE APPENDIX 11-2 HEMATOLOGY(INDIVIDUAL) : FEMALE APPENDIX 12-1 BIOCHEMISTRY(INDIVIDUAL) : MALE APPENDIX 12-2 BIOCHEMISTRY(INDIVIDUAL) : FEMALE APPENDIX 13-1 GROSS FINDINGS(INDIVIDUAL) : MALE APPENDIX 13-2 GROSS FINDINGS(INDIVIDUAL) : FEMALE APPENDIX 14-1 ORGAN WEIGHT, ABSOLUTE(INDIVIDUAL) : MALE APPENDIX 14-2 ORGAN WEIGHT, ABSOLUTE(INDIVIDUAL) : FEMALE APPENDIX 15-1 ORGAN WEIGHT, RELATIVE(INDIVIDUAL) : MALE APPENDIX 15-2 ORGAN WEIGHT, RELATIVE(INDIVIDUAL) : FEMALE APPENDIX 16-1 HISTOPATHOLOGICAL FINDINGS(INDIVIDUAL) : MALE APPENDIX 16-2 HISTOPATHOLOGICAL FINDINGS(INDIVIDUAL) : FEMALE APPENDIX 17-1 CAUSE OF DEATH(INDIVIDUAL): MALE APPENDIX 17-2 CAUSE OF DEATH(INDIVIDUAL): FEMALE
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APPENDIX 1-1
IDENTITY OF TITANIUM DIOXIDE
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(Study No. 0883)
IDENTITY OF TITANIUM DIOXIDE Test Substance : Titanium dioxide (TAYCA CORPORATION) Lot No. : 6545 1. Atomic Absorption Spectrophotometer Instrument : Z-5010 Atomic Absorption Spectrophotometer (Hitachi, Ltd.) Atomization : Graphite atomizer
Atomization temperature : 2700℃ Absorbance : 364.3 nm Injection volume : 20 μL
Titanium content (%)
Theoretical titanium value 60.0* Titanium content in the titanium oxide 60.4
*Theoretical titanium value was calculated by titanium element(48) and oxide element(16).
Result: The titanium content in the titanium oxide was consistent with theoretical value.
2. Conclusion: The test substance was identified as titanium dioxide by atomic absorption spectrophotometers.
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APPENDIX 1-2
STABILITY OF TITANIUM DIOXIDE
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(Study No. 0883)
STABILITY OF TITANIUM DIOXIDE Test Substance : Titanium dioxide (TAYCA CORPORATION) Lot No. : 6545 1. Atomic Absorption Spectrophotometer Instrument : Z-5010 Atomic Absorption Spectrophotometer (Hitachi, Ltd.) Atomization : Graphite atomizer
Atomization temperature : 2700℃ Absorbance : 364.3 nm Injection volume : 20 μL
Date Analyzed Titanium content (%) 2017.02.01 60.4 2019.02.18 59.8
Result: The content of titanium in the test substance before and after use of the test substance was measured with an atomic absorption photometer. As a result, the content of titanium in the test substance before use almost agreed with the content of titanium in the test substance after use.
2. Conclusion: The test substance was stable for the period that the test substance had been used for the study.
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APPENDIX 2
AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS
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(Study No. 0883)
AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS 1-WEEK ON ADMINISTRATION
0 18 0.003 0.36 100.00 0.003 0.37 100.00 0.004 0.46 100.001 10 0.008 0.96 99.64 0.006 0.74 99.63 0.009 1.03 99.542 5.6 0.016 1.92 98.68 0.012 1.48 98.89 0.015 1.72 98.513 3.2 0.057 6.84 96.76 0.072 8.89 97.41 0.063 7.23 96.794 1.8 0.215 25.81 89.92 0.203 25.06 88.52 0.267 30.65 89.555 1.0 0.323 38.78 64.11 0.338 41.73 63.46 0.347 39.84 58.906 0.56 0.160 19.21 25.33 0.135 16.67 21.73 0.135 15.50 19.067 0.32 0.043 5.16 6.12 0.030 3.70 5.06 0.024 2.76 3.568 0.18 0.008 0.96 0.96 0.011 1.36 1.36 0.007 0.80 0.809 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 1000.810- -Total
Weight (mg)
Stage No. (μm)
0.5 mg/m3
Flow︓30ℓ/min Time︓64min
CumulativeRate (%)
Mass Fraction(%)
0.833
2 mg/m3
Flow︓30ℓ/min Time︓16min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%)
0.871 -
8 mg/m3
Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%)
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AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS(CONTINUED) 14-WEEK ON ADMINISTRATION
0 18 0.004 0.52 100.00 0.005 0.61 100.00 0.005 0.60 100.001 10 0.010 1.29 99.48 0.010 1.21 99.39 0.008 0.96 99.402 5.6 0.012 1.55 98.19 0.019 2.30 98.18 0.013 1.56 98.443 3.2 0.069 8.91 96.64 0.070 8.47 95.88 0.067 8.05 96.884 1.8 0.192 24.81 87.73 0.225 27.24 87.41 0.248 29.81 88.825 1.0 0.314 40.57 62.92 0.289 34.99 60.17 0.315 37.86 59.016 0.56 0.138 17.83 22.35 0.162 19.61 25.18 0.143 17.19 21.157 0.32 0.027 3.49 4.52 0.034 4.12 5.57 0.028 3.37 3.978 0.18 0.008 1.03 1.03 0.012 1.45 1.45 0.005 0.60 0.609 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 100 -Total 0.774 - 0.826 - 0.832
CumulativeRate (%)
Stage No. (μm)
0.5 mg/m3 2 mg/m3 8 mg/m3
Flow︓30ℓ/min Time︓64min Flow︓30ℓ/min Time︓16min Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)
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AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS(CONTINUED) 27-WEEK ON ADMINISTRATION
0 18 0.003 0.39 100.00 0.005 0.63 100.00 0.004 0.47 100.001 10 0.009 1.18 99.61 0.008 1.01 99.37 0.008 0.94 99.532 5.6 0.014 1.83 98.43 0.018 2.28 98.35 0.015 1.76 98.593 3.2 0.059 7.72 96.60 0.063 7.98 96.07 0.062 7.26 96.844 1.8 0.214 28.01 88.87 0.214 27.12 88.09 0.244 28.57 89.585 1.0 0.291 38.09 60.86 0.285 36.12 60.96 0.305 35.71 61.016 0.56 0.128 16.75 22.77 0.147 18.63 24.84 0.166 19.44 25.297 0.32 0.035 4.58 6.02 0.040 5.07 6.21 0.040 4.68 5.858 0.18 0.011 1.44 1.44 0.009 1.14 1.14 0.010 1.17 1.179 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 100 -Total 0.764 - 0.789 - 0.854
CumulativeRate (%)
Stage No. (μm)
0.5 mg/m3 2 mg/m3 8 mg/m3
Flow︓30ℓ/min Time︓64min Flow︓30ℓ/min Time︓16min Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)
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AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS(CONTINUED) 40-WEEK ON ADMINISTRATION
0 18 0.004 0.48 100.00 0.003 0.39 100.00 0.003 0.39 100.001 10 0.010 1.20 99.52 0.008 1.03 99.61 0.008 1.03 99.612 5.6 0.025 3.00 98.32 0.017 2.19 98.59 0.017 2.20 98.583 3.2 0.062 7.45 95.31 0.048 6.17 96.40 0.052 6.72 96.384 1.8 0.216 25.96 87.86 0.234 30.08 90.23 0.213 27.52 89.665 1.0 0.312 37.50 61.90 0.297 38.17 60.15 0.310 40.05 62.146 0.56 0.165 19.83 24.40 0.139 17.87 21.98 0.139 17.96 22.097 0.32 0.034 4.09 4.57 0.028 3.60 4.11 0.028 3.62 4.138 0.18 0.004 0.48 0.48 0.004 0.51 0.51 0.004 0.52 0.529 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 100 -Total 0.832 - 0.778 - 0.774
CumulativeRate (%)
Stage No. (μm)
0.5 mg/m3 2 mg/m3 8 mg/m3
Flow︓30ℓ/min Time︓64min Flow︓30ℓ/min Time︓16min Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)
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(Study No. 0883)
AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS(CONTINUED) 53-WEEK ON ADMINISTRATION
0 18 0.004 0.50 100.00 0.004 0.56 100.00 0.002 0.22 100.001 10 0.009 1.13 99.50 0.009 1.25 99.44 0.005 0.55 99.782 5.6 0.019 2.37 98.37 0.016 2.23 98.19 0.012 1.31 99.233 3.2 0.058 7.25 96.00 0.055 7.65 95.97 0.069 7.54 97.924 1.8 0.237 29.63 88.75 0.209 29.07 88.32 0.244 26.67 90.385 1.0 0.303 37.88 59.12 0.283 39.36 59.25 0.362 39.56 63.726 0.56 0.144 18.00 21.25 0.112 15.58 19.89 0.175 19.13 24.157 0.32 0.021 2.63 3.25 0.025 3.48 4.31 0.042 4.59 5.038 0.18 0.005 0.62 0.62 0.006 0.83 0.83 0.004 0.44 0.449 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 100 -Total 0.800 - 0.719 - 0.915
CumulativeRate (%)
Stage No. (μm)
0.5 mg/m3 2 mg/m3 8 mg/m3
Flow︓30ℓ/min Time︓64min Flow︓30ℓ/min Time︓16min Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)
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(Study No. 0883)
AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS(CONTINUED) 66-WEEK ON ADMINISTRATION
0 18 0.004 0.49 100.00 0.003 0.39 100.00 0.005 0.70 100.001 10 0.009 1.11 99.51 0.007 0.92 99.61 0.008 1.12 99.302 5.6 0.017 2.10 98.40 0.015 1.97 98.69 0.014 1.96 98.183 3.2 0.055 6.78 96.30 0.062 8.13 96.72 0.050 6.99 96.224 1.8 0.237 29.22 89.52 0.186 24.38 88.60 0.190 26.57 89.235 1.0 0.297 36.62 60.30 0.313 41.02 64.22 0.290 40.56 62.666 0.56 0.150 18.50 23.67 0.135 17.69 23.20 0.124 17.34 22.107 0.32 0.033 4.07 5.18 0.036 4.72 5.50 0.029 4.06 4.768 0.18 0.009 1.11 1.11 0.006 0.79 0.79 0.005 0.70 0.709 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 100 -Total 0.811 - 0.763 - 0.715
CumulativeRate (%)
Stage No. (μm)
0.5 mg/m3 2 mg/m3 8 mg/m3
Flow︓30ℓ/min Time︓64min Flow︓30ℓ/min Time︓16min Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)
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AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS(CONTINUED) 79-WEEK ON ADMINISTRATION
0 18 0.002 0.25 100.00 0.003 0.39 100.00 0.003 0.34 100.001 10 0.008 0.99 99.75 0.006 0.78 99.61 0.005 0.57 99.662 5.6 0.013 1.61 98.76 0.014 1.81 98.83 0.016 1.82 99.093 3.2 0.077 9.54 97.15 0.052 6.74 97.02 0.088 10.03 97.264 1.8 0.239 29.62 87.61 0.221 28.63 90.28 0.218 24.86 87.235 1.0 0.306 37.92 57.99 0.291 37.69 61.66 0.326 37.17 62.376 0.56 0.125 15.49 20.07 0.142 18.39 23.96 0.181 20.64 25.207 0.32 0.032 3.97 4.58 0.033 4.27 5.57 0.034 3.88 4.568 0.18 0.005 0.62 0.62 0.010 1.30 1.30 0.006 0.68 0.689 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 100 -Total 0.807 - 0.772 - 0.877
CumulativeRate (%)
Stage No. (μm)
0.5 mg/m3 2 mg/m3 8 mg/m3
Flow︓30ℓ/min Time︓64min Flow︓30ℓ/min Time︓16min Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)
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(Study No. 0883)
AEROSOL PARTICLE SIZE DISTRIBUTION ANALYSIS(CONTINUED) 92-WEEK ON ADMINISTRATION
0 18 0.002 0.24 100.00 0.003 0.39 100.00 0.003 0.42 100.001 10 0.009 1.09 99.76 0.007 0.92 99.61 0.006 0.83 99.582 5.6 0.016 1.94 98.67 0.015 1.97 98.69 0.012 1.66 98.753 3.2 0.084 10.18 96.73 0.051 6.69 96.72 0.062 8.60 97.094 1.8 0.231 28.00 86.55 0.211 27.69 90.03 0.198 27.46 88.495 1.0 0.299 36.24 58.55 0.278 36.48 62.34 0.284 39.39 61.036 0.56 0.140 16.97 22.30 0.152 19.95 25.85 0.129 17.89 21.647 0.32 0.033 4.00 5.33 0.034 4.46 5.91 0.022 3.05 3.748 0.18 0.011 1.33 1.33 0.011 1.44 1.44 0.005 0.69 0.699 0.10 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
10 0.056 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0011 0.032 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0012 0.018 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.0013 0.010 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
Final ~0.005 0.000 0.00 0.00 0.000 0.00 0.00 0.000 0.00 0.00
100 100 100 -Total 0.825 - 0.762 - 0.721
CumulativeRate (%)
Stage No. (μm)
0.5 mg/m3 2 mg/m3 8 mg/m3
Flow︓30ℓ/min Time︓64min Flow︓30ℓ/min Time︓16min Flow︓30ℓ/min Time︓4min
Weight (mg) Mass Fraction(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)Cumulative
Rate (%) Weight (mg)Mass Fraction
(%)
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APPENDIX 3
ENVIRONMENTAL CONDITION OF INHALATION CHAMBER
(CARCINOGENICITY STUDY GROUPS)
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(Study No.0883)
ENVIRONMENTAL CONDITIONS OF INHALATION CHAMBER
Temperature Humidity Ventilation Rate Air Change(℃) (%) (L/min) (time/h)
Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean
Control 22.8 ± 0.0 57.2 ± 0.6 1673.4 ± 2.4 10.00.5 mg/m3 22.9 ± 0.0 56.5 ± 1.0 1667.3 ± 3.5 10.02 mg/m3 22.7 ± 0.0 57.8 ± 1.1 1670.6 ± 3.5 10.08 mg/m3 22.8 ± 0.0 56.5 ± 0.8 1668.3 ± 3.6 10.0
Group Name
(CARCINOGENICITY STUDY GROUPS)
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APPENDIX 4
ENVIRONMENTAL CONDITION OF INHALATION CHAMBER
(SATELLITE GROUPS)
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(Study No.0883)
ENVIRONMENTAL CONDITIONS OF INHALATION CHAMBER
1~52 WEEKS (EXPOSURE PERIOD)
Temperature Humidity Ventilation Rate Air Change(℃) (%) (L/min) (time/h)
Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean
Control 22.8 ± 0.0 57.6± 0.5 1673.6± 2.0 10.00.5 mg/m3 22.8 ± 0.0 57.2 ± 0.7 1668.0 ± 2.7 10.02 mg/m3 22.7 ± 0.0 58.5 ± 0.7 1670.2 ± 2.5 10.08 mg/m3 22.9± 0.0 56.6 ±1.0 1666.8± 2.7 10.0
Temperature Humidity Ventilation Rate Air Change(℃) (%) (L/min) (time/h)
Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean
53~78 WEEKS 22.6 ± 0.1 57.2± 1.6 1668.4 ± 3.9 10.0
79~104 WEEKS 22.6 ± 0.1 57.3± 0.6 1664.9 ± 5.1 10.0
(SATELLITE GROUPS)
Group Name
53~104 WEEKS (RECOVERY PERIOD)
RECOVERYPERIOD
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APPENDIX 5
METHODS, UNITS AND DECIMAL PLACE
FOR HEMATOLOGY AND BIOCHEMISTRY
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(Study No. 0883)
METHODS, UNITS AND DECIMAL PLACE FOR HEMATOLOGY AND BIOCHEMISTRY
Item Method Unit Decimal place
Hematology Red blood cell (RBC) Hydrodynamically focussed DC detection
method 1) ×106/μL 2
Hemoglobin(Hgb) SLS-Hemoglobin method 1) g/dL 1 Hematocrit(Hct) Hydrodynamically focussed DC detection
method 1) % 1
Mean corpuscular volume(MCV) Calculated as Hct/RBC×10 1) fL 1 Mean corpuscular hemoglobin(MCH) Calculated as Hgb/RBC×10 1) pg 1 Mean corpuscular hemoglobin concentration (MCHC)
Calculated as Hgb/Hct×100 1) g/dL 1
Platelet Hydrodynamically focussed DC detection method 1)
×103/μL 0
Reticulocyte Flow cytometry method using semiconductor laser 1)
% 1
White blood cell(WBC) Flow cytometry method using semiconductor laser 1)
×103/μL 2
Differential WBC Flow cytometry method using semiconductor laser 1)
% 1
Biochemistry Total protein(TP) Biuret method 2) g/dL 1 Albumin (Alb) BCG method 2) g/dL 1 A/G ratio Calculated as Alb/(TP-Alb) 2) - 1 T-bilirubin BOD method 2) mg/dL 2 Glucose GlcK・G-6-PDH method 2) mg/dL 0 T-cholesterol CE・COD・POD method 2) mg/dL 0 Triglyceride MGLP・GK・GPO・POD method 2) mg/dL 0 Phospholipid PLD・ChOD・POD method 2) mg/dL 0 Aspartate aminotransferase (AST) JSCC method 2) U/L 0 Alanine aminotransferase (ALT) JSCC method 2) U/L 0 Lactate dehydrogenase (LDH) JSCC method 2) U/L 0 Alkaline phosphatase (ALP) JSCC method 2) U/L 0 γ-Glutamyl transpeptidase (γ-GTP) JSCC method 2) U/L 1 Creatine kinase (CK) JSCC method 2) U/L 0 Urea nitrogen Urease・GLDH method 2) mg/dL 1 Creatinine Creatinase・SOD・POD method 2) mg/dL 2 Sodium Ion selective electrode method 2) mEq/L 0 Potassium Ion selective electrode method 2) mEq/L 1 Chloride Ion selective electrode method 2) mEq/L 0 Calcium OCPC method 2) mg/dL 1 Inorganic phosphorus PNP・XOD・POD method 2) mg/dL 1
1) Automated Hematology Analyzer (XN-2000V:Sysmex Corporation) 2) Automatic analyzer (Hitachi 7080:Hitachi High-Tech Corporation)
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APPENDIX 6
METHODS, UNITS AND DECIMAL PLACE
FOR HEMATOLOGY AND BIOCHEMISTRY OF BALF
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(Study No. 0883)
METHODS, UNITS AND DECIMAL PLACE FOR CYTOLOGY AND BIOCHEMISTRY OF BALF
Method Unit Decimal
place Cytology Total cell count Flow Cytometry method 1) ×103/μL 2 Differential Visual Observation method 1)
(May-Grunwald-Giemsa stain) % 1
Biochemistry Phospholipid PLD-ChoD-POD method 2) mg/dL 0 Alkaline phosphatase (ALP) JSCC method 2) U/L 0 γ-Glutamyl transpeptidase (γ-GTP) JSCC method 2) U/L 1
1) Automated Hematology Analyzer (XN-2000V:Sysmex Corporation) 2) Automatic analyzer (Hitachi 7080:Hitachi High-Tech Corporation)
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APPENDIX 7-1
CLINICAL OBSERVATION(INDIVIDUAL) : MALE
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 1- 7- 1 2- 7- 1 3- 7- 1 4- 7- 1 5- 7- 1 6- 7- 1 7- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 2
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 8- 7- 1 9- 7- 1 10- 7- 1 11- 7- 1 12- 7- 1 13- 7- 1 14- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 3
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 15- 7- 1 16- 7- 1 17- 7- 1 18- 7- 1 19- 7- 1 20- 7- 1 21- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 4
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 22- 7- 1 23- 7- 1 24- 7- 1 25- 7- 1 26- 7- 1 27- 7- 1 28- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 5
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 29- 7- 1 30- 7- 1 31- 7- 1 32- 7- 1 33- 7- 1 34- 7- 1 35- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 6
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 36- 7- 1 37- 7- 1 38- 7- 1 39- 7- 1 40- 7- 1 41- 7- 1 42- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 7
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 43- 7- 1 44- 7- 1 45- 7- 1 46- 7- 1 47- 7- 1 48- 7- 1 49- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 8
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 50- 7- 1 51- 7- 1 52- 7- 1 53- 7- 1 54- 7- 1 55- 7- 1 56- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 9
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 57- 7- 1 58- 7- 1 59- 7- 1 60- 7- 1 61- 7- 1 62- 7- 1 63- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 MORIBUND( 57-7) ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 10
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 64- 7- 1 65- 7- 1 66- 7- 1 67- 7- 1 68- 7- 1 69- 7- 1 70- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 NON REMARKABLE NON REMARKABLE NON REMARKABLE PARALYTIC GAIT t PARALYTIC GAIT t DEAD( 69-3) ALREADY DEAD
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 11
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 71- 7- 1 72- 7- 1 73- 7- 1 74- 7- 1 75- 7- 1 76- 7- 1 77- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 12
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 78- 7- 1 79- 7- 1 80- 7- 1 81- 7- 1 82- 7- 1 83- 7- 1 84- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE ANEMIA
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1018 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 13
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 85- 7- 1 86- 7- 1 87- 7- 1 88- 7- 1 89- 7- 1 89- 7- 2 90- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1003 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1005 MORIBUND( 85-5) ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1009 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NORMAL NON REMARKABLE
1017 NON REMARKABLE NON REMARKABLE INTERNAL MASS INTERNAL MASS INTERNAL MASS NORMAL INTERNAL MASS
ANEMIA ANEMIA ANEMIA
1018 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 14
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 91- 7- 1 92- 7- 1 93- 7- 1 94- 7- 1 95- 7- 1 96- 7- 1 97- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1004 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1006 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NON REMARKABLE NON REMARKABLE NON REMARKABLE EXTERNAL MASS EXTERNAL MASS EXTERNAL MASS EXTERNAL MASS
M.ABDOMEN 5a M.ABDOMEN 5a M.ABDOMEN 7b M.ABDOMEN 7b
1008 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 NON REMARKABLE MORIBUND( 92-7) ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1010 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE EXTERNAL MASS EXTERNAL MASS EXTERNAL MASS
M.HINDLIMB 5d M.HINDLIMB 5d M.HINDLIMB 5d
1012 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE ANEMIA NON REMARKABLE
1017 INTERNAL MASS INTERNAL MASS INTERNAL MASS MORIBUND( 94-3) ALREADY DEAD ALREADY DEAD ALREADY DEAD
ANEMIA ANEMIA ANEMIA
1018 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 15
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 97- 7- 2 98- 7- 1 99- 7- 1 100- 7- 1 101- 7- 1 102- 7- 1 103- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1002 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1003 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1004 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1005 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1006 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1007 NORMAL EXTERNAL MASS EXTERNAL MASS DEAD(100-4) ALREADY DEAD ALREADY DEAD ALREADY DEAD
M.ABDOMEN 7b M.ABDOMEN 8b
1008 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1009 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1010 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1011 NORMAL EXTERNAL MASS EXTERNAL MASS EXTERNAL MASS EXTERNAL MASS EXTERNAL MASS EXTERNAL MASS
M.HINDLIMB 5d M.HINDLIMB 5d M.HINDLIMB 5d M.HINDLIMB 5d M.HINDLIMB 5d M.HINDLIMB 5d
1012 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1013 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1014 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1015 NORMAL NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1016 NORMAL NON REMARKABLE NON REMARKABLE ANEMIA ANEMIA ANEMIA MORIBUND(103-1)
IRREGULAR BREATHING
1017 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
1018 ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD ALREADY DEAD
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 16
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 103- 7- 2 104- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1001 NORMAL NON REMARKABLE
1002 NORMAL NON REMARKABLE
1003 ALREADY DEAD ALREADY DEAD
1004 NORMAL NON REMARKABLE
1005 ALREADY DEAD ALREADY DEAD
1006 NORMAL NON REMARKABLE
1007 ALREADY DEAD ALREADY DEAD
1008 NORMAL EXTERNAL MASS
M.ABDOMEN 4b
1009 ALREADY DEAD ALREADY DEAD
1010 NORMAL NON REMARKABLE
1011 NORMAL EXTERNAL MASS
M.HINDLIMB 6d
1012 NORMAL NON REMARKABLE
1013 NORMAL NON REMARKABLE
1014 NORMAL NON REMARKABLE
1015 NORMAL NON REMARKABLE
1016 ALREADY DEAD ALREADY DEAD
1017 ALREADY DEAD ALREADY DEAD
1018 ALREADY DEAD ALREADY DEAD
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 17
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 1- 7- 1 2- 7- 1 3- 7- 1 4- 7- 1 5- 7- 1 6- 7- 1 7- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1019 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1020 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1021 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1022 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1023 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1024 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1025 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1026 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1027 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1028 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1029 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1030 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1031 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1032 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1033 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1034 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 18
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 8- 7- 1 9- 7- 1 10- 7- 1 11- 7- 1 12- 7- 1 13- 7- 1 14- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1019 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1020 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1021 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1022 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1023 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1024 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1025 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1026 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1027 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1028 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1029 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1030 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1031 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1032 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1033 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1034 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 19
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 15- 7- 1 16- 7- 1 17- 7- 1 18- 7- 1 19- 7- 1 20- 7- 1 21- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1019 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1020 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1021 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1022 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1023 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1024 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1025 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1026 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1027 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1028 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1029 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1030 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1031 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1032 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1033 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1034 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 20
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 22- 7- 1 23- 7- 1 24- 7- 1 25- 7- 1 26- 7- 1 27- 7- 1 28- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1019 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1020 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1021 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1022 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1023 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1024 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1025 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1026 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1027 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1028 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1029 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1030 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1031 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1032 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1033 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1034 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 21
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 29- 7- 1 30- 7- 1 31- 7- 1 32- 7- 1 33- 7- 1 34- 7- 1 35- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1019 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1020 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1021 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1022 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1023 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1024 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1025 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1026 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1027 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1028 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1029 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1030 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1031 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1032 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1033 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1034 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 22
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 36- 7- 1 37- 7- 1 38- 7- 1 39- 7- 1 40- 7- 1 41- 7- 1 42- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1019 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1020 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1021 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1022 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1023 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1024 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1025 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1026 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1027 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1028 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1029 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1030 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1031 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1032 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1033 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1034 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
_____________________________________________________________________________________________________________________________________________________________________________________________________
(HAN230) BAIS6
-
STUDY NO. : 0883 CLINICAL OBSERVATION (TIME-RELATED)
ANIMAL : RAT F344/DuCrlCrlj[F344/DuCrj] ALL ANIMALS
REPORT TYPE : C 104SEX : MALE Group Name Control PAGE : 23
_____________________________________________________________________________________________________________________________________________________________________________________________________
Animal Administration Week-day____________________________________________________________________________________________________________________________________________________________________
ID-NO. 43- 7- 1 44- 7- 1 45- 7- 1 46- 7- 1 47- 7- 1 48- 7- 1 49- 7- 1
_____________________________________________________________________________________________________________________________________________________________________________________________________
1019 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1020 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1021 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1022 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1023 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1024 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1025 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1026 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1027 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1028 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1029 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1030 NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE NON REMARKABLE
1031 N