Apparatus for the treatment of blood in particular for hemodialysis and hemofiltration
1
ii New Patents state of 40 to 250 angstroms, and the mass trans- fer coefficient for beta2-microglobulin of at least 2* 1 O-5 cm/set. The hollow fiber membrane pre- ferably contains polyethylene glycol and has the albumin sieving coefficient not larger than 0.10. The hollow fiber membrane is especially useful for hemofiltration therapy such as hemodialysis. 4919817 APPARATUS FOR THE TREATMENT OF BLOOD IN PARTICULAR FOR HEMODIALYSIS AND HEMOFILTRATION BLOOD CELL WASHING SYSTEMS AND METHODS Wilfried Schal, Bad Homburg, Federal Republic Of Germany assigned to Fresenius AG Donald W Schoendorfer, Lee H Williamson as- signed to Baxter International Inc A system and method for cleaning contaminants from shed blood to enable reinfusion of a cell concentrate in the patient employs successive rotary membrane filtering stages in which Taylor vortices are generated. Shed blood led into the first rotary membrane stage is filtered to a hematocrit in the range of 50-60 with some of the waste matter being removed. The intermediate cell concentrate is passed to the second filter stage where further waste matter is initially extracted. At any intermediate region, however, a major amount of wash solution is fed into the concentrate and effectively mixed by the Taylor vortices. In the remaining length of the second filter stage waste matter is entrained in wash solution and both waste and wash solution are filtered out to provide a cell concentrate from which the great majority of contaminants have been removed. 4923438 BLOOD RECOVERY SYSTEM AND METHOD Alfred V Vasconcellos, Preston J Keeler assigned to Pfizer Hospital Products Group Inc An intraoperative blood recovery system and method for salvaging operative blood while simultaneously delivering previously collected blood to a reinfusion system. A blood collection and transfer reservoir, having multiple compart- ments which can be separated by vacuum or pre- ssure barriers, is designed to maintain a continuous suction for blood inflow while blood previously collected can be simultaneously transported through the reservoir to achieve an uninterrupted flow of blood into and delivery of blood out of the reservoir. 4923598 The apparatus for hemodialysis and hemofiltra- tion comprises an extracorporeal blood circuit comprising a dialyzer and/or filter arrangement. For determining the fluid withdrawal per unit time and the total amount of fluid withdrawn flow sensors in conjunction with an evaluating unit are inserted into the blood circuit upstream and downstream of the dialyzer or filter arrange- ment. The flow measurement is by the ultrasonic Doppler principle and for obtaining high ac- curacy the sensors comprise measuring inserts belonging to the blood tubing system and having special means for defined coupling-in and coupling-out and precise conduction of the ul- trasonic waves. Apart from the measurement, means are provided for regulating the net fluid withdrawal. 4933844 MEASUREMENT OF BLOOD LIPOPROTEIN CONSTITUENTS BY ANALYSIS OF DATA ACQUIRED FROM AN NMR SPECTROMETER James D Otvos A method and apparatus for analyzing blood plasma to determine the concentration of its lipoprotein constituents, VLDL, LDL, HDL and proteins includes obtaining the NMR chem- ical shift spectrum of a sample. Stored reference NMR spectra of the lipoprotein constituents are added together to form a lineshape that best fits the measured blood plasma NMR spectrum, and from this, the concentration of each lipoprotein constituent in the blood plasma is determined.
Transcript of Apparatus for the treatment of blood in particular for hemodialysis and hemofiltration
ii New Patents
state of 40 to 250 angstroms, and the mass trans- fer coefficient for beta2-microglobulin of at least 2* 1 O-5 cm/set. The hollow fiber membrane pre- ferably contains polyethylene glycol and has the albumin sieving coefficient not larger than 0.10. The hollow fiber membrane is especially useful for hemofiltration therapy such as hemodialysis.
4919817
APPARATUS FOR THE TREATMENT OF BLOOD IN
PARTICULAR FOR HEMODIALYSIS AND
HEMOFILTRATION
BLOOD CELL WASHING SYSTEMS AND METHODS
Wilfried Schal, Bad Homburg, Federal Republic Of Germany assigned to Fresenius AG
Donald W Schoendorfer, Lee H Williamson as- signed to Baxter International Inc
A system and method for cleaning contaminants from shed blood to enable reinfusion of a cell concentrate in the patient employs successive rotary membrane filtering stages in which Taylor vortices are generated. Shed blood led into the first rotary membrane stage is filtered to a hematocrit in the range of 50-60 with some of the waste matter being removed. The intermediate cell concentrate is passed to the second filter stage where further waste matter is initially extracted. At any intermediate region, however, a major amount of wash solution is fed into the concentrate and effectively mixed by the Taylor vortices. In the remaining length of the second filter stage waste matter is entrained in wash solution and both waste and wash solution are filtered out to provide a cell concentrate from which the great majority of contaminants have been removed.
4923438
BLOOD RECOVERY SYSTEM AND METHOD
Alfred V Vasconcellos, Preston J Keeler assigned to Pfizer Hospital Products Group Inc
An intraoperative blood recovery system and method for salvaging operative blood while simultaneously delivering previously collected blood to a reinfusion system. A blood collection and transfer reservoir, having multiple compart- ments which can be separated by vacuum or pre- ssure barriers, is designed to maintain a continuous suction for blood inflow while blood previously collected can be simultaneously transported through the reservoir to achieve an
uninterrupted flow of blood into and delivery of blood out of the reservoir.
4923598
The apparatus for hemodialysis and hemofiltra- tion comprises an extracorporeal blood circuit comprising a dialyzer and/or filter arrangement. For determining the fluid withdrawal per unit time and the total amount of fluid withdrawn flow sensors in conjunction with an evaluating unit are inserted into the blood circuit upstream and downstream of the dialyzer or filter arrange- ment. The flow measurement is by the ultrasonic Doppler principle and for obtaining high ac- curacy the sensors comprise measuring inserts belonging to the blood tubing system and having special means for defined coupling-in and coupling-out and precise conduction of the ul- trasonic waves. Apart from the measurement, means are provided for regulating the net fluid withdrawal.
4933844
MEASUREMENT OF BLOOD LIPOPROTEIN CONSTITUENTS
BY ANALYSIS OF DATA ACQUIRED FROM AN NMR
SPECTROMETER
James D Otvos
A method and apparatus for analyzing blood plasma to determine the concentration of its lipoprotein constituents, VLDL, LDL, HDL and proteins includes obtaining the NMR chem- ical shift spectrum of a sample. Stored reference NMR spectra of the lipoprotein constituents are added together to form a lineshape that best fits the measured blood plasma NMR spectrum, and from this, the concentration of each lipoprotein constituent in the blood plasma is determined.
